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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for neurod1

Z-value: 0.72

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Transcription factors associated with neurod1

Gene Symbol Gene ID Gene Info
neurod1
ENSDARG00000019566 neuronal differentiation 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
neurod1dr11_v1_chr9_-_44295071_44295071-0.663.1e-03Click!

Activity profile of neurod1 motif

Sorted Z-values of neurod1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr23_-_10177442 2.03 ENSDART00000144280
ENSDART00000129044
krt5
keratin 5
chr1_+_218524 1.93 ENSDART00000109529
tmco3
transmembrane and coiled-coil domains 3
chr17_-_51829310 1.47 ENSDART00000154544
numb
numb homolog (Drosophila)
chr6_+_33076839 1.42 ENSDART00000073755
ENSDART00000122242
pomgnt1
protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-)
chr7_+_55950229 1.42 ENSDART00000082780
ACSF3
acyl-CoA synthetase family member 3
chr2_-_17114852 1.33 ENSDART00000006549
pif1
PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)
chr16_+_29509133 1.28 ENSDART00000112116
ctss2.1
cathepsin S, ortholog2, tandem duplicate 1
chr11_-_2270069 1.24 ENSDART00000189005
znf740a
zinc finger protein 740a
chr1_+_21937201 1.24 ENSDART00000087729
kdm4c
lysine (K)-specific demethylase 4C
chr5_+_25762271 1.23 ENSDART00000181323
tmem2
transmembrane protein 2
chr16_-_51151993 1.22 ENSDART00000156255
ago1
argonaute RISC catalytic component 1
chr9_-_1200187 1.22 ENSDART00000158760
ino80da
INO80 complex subunit Da
chr3_-_30885250 1.21 ENSDART00000109104
kmt5c
lysine methyltransferase 5C
chr5_+_36661058 1.18 ENSDART00000125653
capns1a
calpain, small subunit 1 a
chr2_-_17115256 1.14 ENSDART00000190488
pif1
PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)
chr11_-_25257045 1.12 ENSDART00000130477
snai1a
snail family zinc finger 1a
chr2_-_49031303 1.11 ENSDART00000143471
cdc34b
cell division cycle 34 homolog (S. cerevisiae) b
chr3_-_61494840 1.10 ENSDART00000101957
baiap2l1b
BAI1-associated protein 2-like 1b
chr3_-_29962345 1.10 ENSDART00000136819
bcat2
branched chain amino-acid transaminase 2, mitochondrial
chr11_-_25257595 1.10 ENSDART00000123567
snai1a
snail family zinc finger 1a
chr4_-_20081621 1.08 ENSDART00000024647
dennd6b
DENN/MADD domain containing 6B
chr1_+_12301913 1.07 ENSDART00000165733
gne
glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
chr5_+_37406358 1.06 ENSDART00000162811
klhl13
kelch-like family member 13
chr13_+_22719789 1.04 ENSDART00000057672
nfkb2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr11_-_43226255 1.03 ENSDART00000172929
sptbn1
spectrin, beta, non-erythrocytic 1
chr1_-_34450784 1.03 ENSDART00000140515
lmo7b
LIM domain 7b
chr17_+_12075805 1.02 ENSDART00000155329
cnsta
consortin, connexin sorting protein a
chr15_-_26931541 1.02 ENSDART00000027563
ccdc9
coiled-coil domain containing 9
chr1_-_34450622 1.01 ENSDART00000083736
lmo7b
LIM domain 7b
chr11_-_35171162 1.01 ENSDART00000017393
traip
TRAF-interacting protein
chr3_-_23574622 1.00 ENSDART00000176012
igf2bp1
insulin-like growth factor 2 mRNA binding protein 1
chr18_-_39787040 1.00 ENSDART00000169916
dmxl2
Dmx-like 2
chr1_-_55118745 0.99 ENSDART00000133915
sertad2a
SERTA domain containing 2a
chr20_+_405811 0.99 ENSDART00000149311
gpr63
G protein-coupled receptor 63
chr1_-_9527200 0.98 ENSDART00000110790
si:ch73-12o23.1
si:ch73-12o23.1
chr5_+_3891485 0.96 ENSDART00000129329
ENSDART00000091711
rpain
RPA interacting protein
chr19_+_43669122 0.96 ENSDART00000139151
si:ch211-193k19.1
si:ch211-193k19.1
chr9_+_48123002 0.96 ENSDART00000099794
ENSDART00000169733
klhl23
kelch-like family member 23
chr2_-_37478418 0.95 ENSDART00000146103
dapk3
death-associated protein kinase 3
chr13_-_12667220 0.94 ENSDART00000079594
fam241a
family with sequence similarity 241 member A
chr21_-_18275226 0.94 ENSDART00000126672
ENSDART00000135239
brd3a
bromodomain containing 3a
chr19_-_868187 0.94 ENSDART00000186626
eomesa
eomesodermin homolog a
chr8_+_12118097 0.93 ENSDART00000081819
endog
endonuclease G
chr6_-_26225814 0.91 ENSDART00000089121
hs2st1b
heparan sulfate 2-O-sulfotransferase 1b
chr19_+_43684376 0.91 ENSDART00000051723
si:ch211-193k19.1
si:ch211-193k19.1
chr24_-_34335265 0.91 ENSDART00000128690
agap3
ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
chr5_-_19932621 0.91 ENSDART00000088881
git2a
G protein-coupled receptor kinase interacting ArfGAP 2a
chr2_-_32237916 0.89 ENSDART00000141418
fam49ba
family with sequence similarity 49, member Ba
chr9_+_22634073 0.88 ENSDART00000181822
etv5a
ets variant 5a
chr8_-_18613948 0.87 ENSDART00000089172
cpox
coproporphyrinogen oxidase
chr6_-_4214297 0.85 ENSDART00000191433
trak2
trafficking protein, kinesin binding 2
chr8_-_23776399 0.84 ENSDART00000114800
INAVA
si:ch211-163l21.4
chr14_+_21722235 0.84 ENSDART00000183667
stx3a
syntaxin 3A
chr1_+_12302073 0.83 ENSDART00000164045
gne
glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
chr20_+_29209767 0.83 ENSDART00000141252
katnbl1
katanin p80 subunit B-like 1
chr2_-_43545342 0.81 ENSDART00000179796
CABZ01058721.1

chr10_-_15854743 0.81 ENSDART00000092343
tjp2a
tight junction protein 2a (zona occludens 2)
chr18_+_3634652 0.80 ENSDART00000159913
lrch3
leucine-rich repeats and calponin homology (CH) domain containing 3
chr8_-_49935358 0.79 ENSDART00000159782
ENSDART00000156841
agtpbp1
CU694202.1
ATP/GTP binding protein 1

chr20_+_29209926 0.78 ENSDART00000152949
ENSDART00000153016
katnbl1
katanin p80 subunit B-like 1
chr17_+_1360192 0.78 ENSDART00000184561
siva1
SIVA1, apoptosis-inducing factor
chr9_+_25096500 0.77 ENSDART00000135074
ENSDART00000180436
ENSDART00000108629
lrch1
leucine-rich repeats and calponin homology (CH) domain containing 1
chr6_-_3992942 0.77 ENSDART00000182328
unc50
unc-50 homolog (C. elegans)
chr6_-_39700965 0.77 ENSDART00000156645
espl1
extra spindle pole bodies like 1, separase
chr7_+_34794829 0.76 ENSDART00000009698
ENSDART00000075089
ENSDART00000173456
esrp2
epithelial splicing regulatory protein 2
chr5_+_6670945 0.76 ENSDART00000185686
pxna
paxillin a
chr20_+_29209615 0.76 ENSDART00000062350
katnbl1
katanin p80 subunit B-like 1
chr24_+_19542323 0.74 ENSDART00000140379
ENSDART00000142830
sulf1
sulfatase 1
chr8_-_19451487 0.74 ENSDART00000184037
zgc:92140
zgc:92140
chr16_-_34212912 0.74 ENSDART00000145017
phactr4b
phosphatase and actin regulator 4b
chr22_-_18241390 0.73 ENSDART00000083879
tmem161a
transmembrane protein 161A
chr18_+_45550783 0.71 ENSDART00000138075
kifc3
kinesin family member C3
chr15_-_20745513 0.71 ENSDART00000187438
tpst1
tyrosylprotein sulfotransferase 1
chr7_+_26844261 0.71 ENSDART00000079165
ext2
exostosin glycosyltransferase 2
chr20_-_44576949 0.70 ENSDART00000148639
ubxn2a
UBX domain protein 2A
chr23_-_31647793 0.70 ENSDART00000145621
sgk1
serum/glucocorticoid regulated kinase 1
chr24_+_19518303 0.70 ENSDART00000027022
ENSDART00000056080
sulf1
sulfatase 1
chr23_-_18057270 0.70 ENSDART00000173385
zgc:92287
zgc:92287
chr16_-_20855730 0.69 ENSDART00000188905
tax1bp1b
Tax1 (human T-cell leukemia virus type I) binding protein 1b
chr20_+_20731633 0.69 ENSDART00000191952
ENSDART00000165224
ppp1r13bb
protein phosphatase 1, regulatory subunit 13Bb
chr20_+_14968031 0.68 ENSDART00000151805
ENSDART00000151448
ENSDART00000063874
ENSDART00000190910
vamp4
vesicle-associated membrane protein 4
chr1_-_51710225 0.68 ENSDART00000057601
ENSDART00000152745
snrpb2
small nuclear ribonucleoprotein polypeptide B2
chr9_+_22929675 0.67 ENSDART00000061299
tsn
translin
chr24_+_19518570 0.67 ENSDART00000056081
sulf1
sulfatase 1
chr3_-_54500354 0.67 ENSDART00000124215
trip10a
thyroid hormone receptor interactor 10a
chr8_+_20488322 0.66 ENSDART00000036630
zgc:101100
zgc:101100
chr23_-_18567088 0.66 ENSDART00000192371
sephs2
selenophosphate synthetase 2
chr16_-_47408135 0.66 ENSDART00000150132
sept7b
septin 7b
chr16_+_35905031 0.66 ENSDART00000162411
sh3d21
SH3 domain containing 21
chr2_+_35732652 0.66 ENSDART00000052666
rasal2
RAS protein activator like 2
chr5_+_62611400 0.66 ENSDART00000132054
abr
active BCR-related
chr3_+_33745014 0.65 ENSDART00000159966
nacc1a
nucleus accumbens associated 1, BEN and BTB (POZ) domain containing a
chr2_+_47471647 0.65 ENSDART00000184199
acsl3b
acyl-CoA synthetase long chain family member 3b
chr11_-_44999858 0.65 ENSDART00000167759
ENSDART00000126845
ldb1b
LIM-domain binding 1b
chr19_-_32888758 0.65 ENSDART00000052080
laptm4b
lysosomal protein transmembrane 4 beta
chr19_-_43639331 0.64 ENSDART00000138009
ENSDART00000086138
fam83hb
family with sequence similarity 83, member Hb
chr15_-_28904371 0.63 ENSDART00000155154
eml2
echinoderm microtubule associated protein like 2
chr2_+_37245382 0.63 ENSDART00000004626
sec62
SEC62 homolog, preprotein translocation factor
chr22_-_21897203 0.62 ENSDART00000158501
ENSDART00000105566
ENSDART00000136795
gna11a
guanine nucleotide binding protein (G protein), alpha 11a (Gq class)
chr2_+_47471943 0.61 ENSDART00000141974
acsl3b
acyl-CoA synthetase long chain family member 3b
chr20_+_23498255 0.61 ENSDART00000149922
palld
palladin, cytoskeletal associated protein
chr20_-_53963515 0.61 ENSDART00000110252
ppp2r5cb
protein phosphatase 2, regulatory subunit B', gamma b
chr5_-_13315726 0.61 ENSDART00000143364
sdf2l1
stromal cell-derived factor 2-like 1
chr21_-_43666420 0.60 ENSDART00000139008
ENSDART00000183996
ENSDART00000183395
si:dkey-229d11.3
si:dkey-229d11.5
si:dkey-229d11.3
si:dkey-229d11.5
chr20_+_52529044 0.60 ENSDART00000158230
ENSDART00000002787
pycr3
pyrroline-5-carboxylate reductase 3
chr24_+_14801844 0.59 ENSDART00000141620
pi15a
peptidase inhibitor 15a
chr3_+_34988670 0.59 ENSDART00000011319
smarce1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
chr6_-_37749711 0.59 ENSDART00000078324
nipa1
non imprinted in Prader-Willi/Angelman syndrome 1
chr1_+_6646529 0.59 ENSDART00000144641
ENSDART00000103701
ENSDART00000138919
ube2f
ubiquitin-conjugating enzyme E2F (putative)
chr10_-_14943281 0.59 ENSDART00000143608
smad2
SMAD family member 2
chr20_+_21268795 0.58 ENSDART00000090016
nudt14
nudix (nucleoside diphosphate linked moiety X)-type motif 14
chr16_+_25171832 0.58 ENSDART00000156416
wu:fe05a04
wu:fe05a04
chr20_-_18794789 0.58 ENSDART00000003834
ccm2
cerebral cavernous malformation 2
chr9_+_48123224 0.58 ENSDART00000141610
klhl23
kelch-like family member 23
chr17_+_32360673 0.57 ENSDART00000155519
si:ch211-139d20.3
si:ch211-139d20.3
chr19_-_12212692 0.57 ENSDART00000142077
ENSDART00000151599
ENSDART00000140834
ENSDART00000078781
znf706
zinc finger protein 706
chr23_-_18057851 0.56 ENSDART00000173075
ENSDART00000173230
ENSDART00000173135
ENSDART00000173431
ENSDART00000173068
ENSDART00000172987
zgc:92287
zgc:92287
chr7_-_29356084 0.56 ENSDART00000075757
gtf2a2
general transcription factor IIA, 2
chr25_-_18948816 0.56 ENSDART00000091549
nt5dc3
5'-nucleotidase domain containing 3
chr19_-_46037835 0.56 ENSDART00000163815
nup153
nucleoporin 153
chr1_+_19538299 0.55 ENSDART00000109416
smc2
structural maintenance of chromosomes 2
chr6_-_1187565 0.55 ENSDART00000191756
txnrd3
thioredoxin reductase 3
chr20_-_3319642 0.55 ENSDART00000186743
ENSDART00000123096
marcksa
myristoylated alanine-rich protein kinase C substrate a
chr25_-_12412704 0.55 ENSDART00000168275
det1
DET1, COP1 ubiquitin ligase partner
chr12_+_32292564 0.55 ENSDART00000152945
ANKFN1
si:ch211-277e21.2
chr17_-_19466319 0.55 ENSDART00000170429
dicer1
dicer 1, ribonuclease type III
chr4_-_4592287 0.55 ENSDART00000155287
rassf3
Ras association (RalGDS/AF-6) domain family member 3
chr3_+_32651697 0.54 ENSDART00000055338
thoc6
THO complex 6
chr23_-_19831739 0.54 ENSDART00000125066
haus7
HAUS augmin-like complex, subunit 7
chr22_+_22437561 0.54 ENSDART00000089622
kif14
kinesin family member 14
chr18_+_12147971 0.53 ENSDART00000162067
ENSDART00000168386
fgd4a
FYVE, RhoGEF and PH domain containing 4a
chr2_-_31833347 0.53 ENSDART00000109460
nol7
nucleolar protein 7
chr7_+_6941583 0.53 ENSDART00000160709
ENSDART00000157634
rbm14b
RNA binding motif protein 14b
chr22_-_18544701 0.53 ENSDART00000132156
cirbpb
cold inducible RNA binding protein b
chr16_+_35536075 0.53 ENSDART00000183618
cited4b
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4b
chr5_+_42259002 0.52 ENSDART00000083778
eral1
Era-like 12S mitochondrial rRNA chaperone 1
chr11_-_28911172 0.52 ENSDART00000168493
igsf21a
immunoglobin superfamily, member 21a
chr12_-_33659328 0.52 ENSDART00000153457
tmem94
transmembrane protein 94
chr5_-_35252761 0.52 ENSDART00000051278
tnpo1
transportin 1
chr18_+_15778110 0.51 ENSDART00000014188
ube2na
ubiquitin-conjugating enzyme E2Na
chr9_+_35017702 0.51 ENSDART00000193640
gabpa
GA binding protein transcription factor, alpha subunit
chr11_+_6902946 0.51 ENSDART00000144006
crtc1b
CREB regulated transcription coactivator 1b
chr10_+_6340478 0.50 ENSDART00000163182
ENSDART00000163722
tpm2
tropomyosin 2 (beta)
chr3_+_16663373 0.50 ENSDART00000100961
zgc:55558
zgc:55558
chr18_-_21047007 0.49 ENSDART00000162702
igf1ra
insulin-like growth factor 1a receptor
chr15_+_34963316 0.49 ENSDART00000153840
si:ch73-95l15.5
si:ch73-95l15.5
chr19_-_24136233 0.49 ENSDART00000143365
thap7
THAP domain containing 7
chr21_+_39100289 0.48 ENSDART00000075958
slc13a2
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
chr22_-_18240968 0.48 ENSDART00000027605
tmem161a
transmembrane protein 161A
chr13_-_8785610 0.48 ENSDART00000021083
calm2b
calmodulin 2b, (phosphorylase kinase, delta)
chr12_-_34852342 0.48 ENSDART00000152968
si:dkey-21c1.1
si:dkey-21c1.1
chr6_-_1187749 0.48 ENSDART00000172544
txnrd3
thioredoxin reductase 3
chr23_+_22873415 0.48 ENSDART00000135130
rerea
arginine-glutamic acid dipeptide (RE) repeats a
chr20_-_43741159 0.47 ENSDART00000192621
si:dkeyp-50f7.2
si:dkeyp-50f7.2
chr23_-_16980213 0.47 ENSDART00000046889
dnmt3bb.3
DNA (cytosine-5-)-methyltransferase beta, duplicate b.3
chr12_-_33459579 0.47 ENSDART00000105562
zgc:91940
zgc:91940
chr17_+_28624321 0.47 ENSDART00000122260
heatr5a
HEAT repeat containing 5a
chr23_-_18057553 0.47 ENSDART00000173102
ENSDART00000058742
zgc:92287
zgc:92287
chr24_+_35387517 0.47 ENSDART00000058571
snai2
snail family zinc finger 2
chr5_+_60919378 0.46 ENSDART00000184915
doc2b
double C2-like domains, beta
chr7_-_59210882 0.46 ENSDART00000170330
ENSDART00000158996
nagk
N-acetylglucosamine kinase
chr12_-_22238004 0.46 ENSDART00000038310
ormdl3
ORMDL sphingolipid biosynthesis regulator 3
chr21_-_41065369 0.46 ENSDART00000143749
larsb
leucyl-tRNA synthetase b
chr23_+_25172682 0.46 ENSDART00000191197
ENSDART00000183497
si:dkey-151g10.3
si:dkey-151g10.3
chr2_+_31308587 0.46 ENSDART00000027090
clul1
clusterin-like 1 (retinal)
chr10_-_14920989 0.45 ENSDART00000184617
smad2
SMAD family member 2
chr21_+_11521163 0.45 ENSDART00000139267
zgc:114104
zgc:114104
chr11_+_18873619 0.45 ENSDART00000176141
magi1b
membrane associated guanylate kinase, WW and PDZ domain containing 1b
chr13_-_6250317 0.45 ENSDART00000180416
tuba4l
tubulin, alpha 4 like
chr5_-_40190949 0.45 ENSDART00000175588
wdfy3
WD repeat and FYVE domain containing 3
chr15_+_29472065 0.44 ENSDART00000154343
gdpd5b
glycerophosphodiester phosphodiesterase domain containing 5b
chr9_-_39624173 0.44 ENSDART00000180106
ENSDART00000126766
erbb4b
erb-b2 receptor tyrosine kinase 4b
chr12_+_21525496 0.44 ENSDART00000152974
ca10a
carbonic anhydrase Xa
chr21_+_6212844 0.44 ENSDART00000150301
fnbp1b
formin binding protein 1b
chr24_-_26995164 0.44 ENSDART00000142864
stag1b
stromal antigen 1b
chr5_-_51998708 0.43 ENSDART00000097194
serinc5
serine incorporator 5
chr2_-_32574944 0.43 ENSDART00000056642
tmub1
transmembrane and ubiquitin-like domain containing 1
chr25_-_37258653 0.43 ENSDART00000131076
rfwd3
ring finger and WD repeat domain 3
chr5_+_58455488 0.43 ENSDART00000038602
ENSDART00000127958
slc37a2
solute carrier family 37 (glucose-6-phosphate transporter), member 2
chr5_-_69923241 0.43 ENSDART00000187389
fktn
fukutin
chr13_+_50778187 0.43 ENSDART00000159597
dntt
deoxynucleotidyltransferase, terminal
chr16_-_42066523 0.42 ENSDART00000180538
ENSDART00000058620
zp3d.1
zona pellucida glycoprotein 3d tandem duplicate 1
chr8_-_49207319 0.42 ENSDART00000022870
fam110a
family with sequence similarity 110, member A
chr13_-_6252498 0.42 ENSDART00000115157
tuba4l
tubulin, alpha 4 like
chr18_-_42313798 0.42 ENSDART00000098639
cntn5
contactin 5
chr3_-_21061931 0.42 ENSDART00000036741
fam57ba
family with sequence similarity 57, member Ba
chr15_-_26568278 0.42 ENSDART00000182609
wdr81
WD repeat domain 81
chr7_-_54217547 0.42 ENSDART00000162777
ENSDART00000188268
ENSDART00000165875
csnk1g1
casein kinase 1, gamma 1
chr10_-_4961923 0.42 ENSDART00000050177
ENSDART00000146066
snx30
sorting nexin family member 30
chr23_-_21758253 0.42 ENSDART00000046613
vps13d
vacuolar protein sorting 13 homolog D (S. cerevisiae)
chr11_-_6880725 0.41 ENSDART00000007204
ddx49
DEAD (Asp-Glu-Ala-Asp) box polypeptide 49
chr6_+_30533504 0.41 ENSDART00000155842
wwc3
WWC family member 3
chr7_+_22399669 0.41 ENSDART00000144375
fgf11a
fibroblast growth factor 11a
chr6_-_51771634 0.41 ENSDART00000073847
blcap
bladder cancer associated protein
chr21_+_8427059 0.41 ENSDART00000143151
dennd1a
DENN/MADD domain containing 1A
chr19_-_42588510 0.40 ENSDART00000102583
sytl1
synaptotagmin-like 1
chr5_-_30145939 0.39 ENSDART00000086795
zbtb44
zinc finger and BTB domain containing 44
chr12_+_19281189 0.38 ENSDART00000153428
tnrc6b
trinucleotide repeat containing 6b
chr10_-_6867282 0.38 ENSDART00000144001
ENSDART00000109744
ppip5k2
diphosphoinositol pentakisphosphate kinase 2
chr24_+_32472155 0.38 ENSDART00000098859
neurod6a
neuronal differentiation 6a

Network of associatons between targets according to the STRING database.

First level regulatory network of neurod1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0034770 histone H4-K20 methylation(GO:0034770) histone H4-K20 trimethylation(GO:0034773)
0.3 1.0 GO:0090004 positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.3 1.0 GO:0097401 regulation of cellular pH reduction(GO:0032847) synaptic vesicle lumen acidification(GO:0097401) regulation of synaptic vesicle lumen acidification(GO:1901546)
0.3 0.9 GO:0055109 invagination involved in gastrulation with mouth forming second(GO:0055109) morphogenesis of an epithelial fold(GO:0060571)
0.3 1.1 GO:0009098 leucine biosynthetic process(GO:0009098)
0.3 2.1 GO:0021910 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910) regulation of myotome development(GO:2000290)
0.3 0.8 GO:1990869 response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869) negative regulation of lymphocyte migration(GO:2000402) negative regulation of T cell migration(GO:2000405)
0.2 1.5 GO:0006921 apoptotic DNA fragmentation(GO:0006309) cellular component disassembly involved in execution phase of apoptosis(GO:0006921) apoptotic nuclear changes(GO:0030262)
0.2 2.5 GO:0000002 mitochondrial genome maintenance(GO:0000002)
0.2 1.4 GO:0016266 O-glycan processing(GO:0016266)
0.2 0.8 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.2 1.0 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.2 0.7 GO:0090161 Golgi ribbon formation(GO:0090161)
0.2 0.8 GO:0098881 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.1 0.4 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.1 0.4 GO:0035973 aggrephagy(GO:0035973)
0.1 1.1 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.1 0.5 GO:1900060 regulation of sphingolipid biosynthetic process(GO:0090153) negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060) regulation of membrane lipid metabolic process(GO:1905038) regulation of ceramide biosynthetic process(GO:2000303)
0.1 0.3 GO:0071431 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.1 0.8 GO:0061055 myotome development(GO:0061055)
0.1 2.2 GO:0008078 mesodermal cell migration(GO:0008078)
0.1 0.7 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
0.1 0.7 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.1 0.9 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1 0.3 GO:0060912 cardiac cell fate specification(GO:0060912)
0.1 0.9 GO:0051189 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.1 1.9 GO:0006047 UDP-N-acetylglucosamine metabolic process(GO:0006047)
0.1 0.3 GO:0090266 regulation of spindle checkpoint(GO:0090231) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.1 0.3 GO:0019284 L-methionine biosynthetic process from S-adenosylmethionine(GO:0019284)
0.1 0.6 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.1 0.7 GO:0006478 protein sulfation(GO:0006477) peptidyl-tyrosine sulfation(GO:0006478)
0.1 0.4 GO:1901911 diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.1 0.5 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.1 0.4 GO:0060049 regulation of protein glycosylation(GO:0060049)
0.1 0.9 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.1 0.7 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.1 0.4 GO:0051148 smooth muscle cell differentiation(GO:0051145) negative regulation of muscle cell differentiation(GO:0051148)
0.1 0.4 GO:0042762 regulation of sulfur metabolic process(GO:0042762)
0.1 0.2 GO:0003408 optic cup formation involved in camera-type eye development(GO:0003408) spinal cord association neuron specification(GO:0021519)
0.1 0.4 GO:0036371 protein localization to T-tubule(GO:0036371)
0.1 1.0 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.1 0.6 GO:0003160 endocardium morphogenesis(GO:0003160)
0.1 0.4 GO:0021877 forebrain neuron fate commitment(GO:0021877)
0.1 0.9 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.1 0.4 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.1 0.5 GO:0031063 regulation of histone deacetylation(GO:0031063)
0.1 0.3 GO:1904292 regulation of ERAD pathway(GO:1904292)
0.1 0.9 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782) protoporphyrinogen IX metabolic process(GO:0046501)
0.1 0.4 GO:0006621 protein retention in ER lumen(GO:0006621)
0.1 0.2 GO:0010898 regulation of triglyceride catabolic process(GO:0010896) positive regulation of triglyceride catabolic process(GO:0010898)
0.1 0.8 GO:0048009 insulin-like growth factor receptor signaling pathway(GO:0048009)
0.0 0.4 GO:1901224 positive regulation of NIK/NF-kappaB signaling(GO:1901224)
0.0 0.5 GO:0032024 positive regulation of insulin secretion(GO:0032024)
0.0 0.7 GO:1903286 positive regulation of sodium ion transport(GO:0010765) positive regulation of sodium ion transmembrane transport(GO:1902307) regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288) positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.0 0.4 GO:0046341 CDP-diacylglycerol biosynthetic process(GO:0016024) CDP-diacylglycerol metabolic process(GO:0046341)
0.0 0.9 GO:0002574 thrombocyte differentiation(GO:0002574)
0.0 0.3 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.0 0.6 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0 0.3 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.0 0.7 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.7 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.0 0.2 GO:0044241 lipid digestion(GO:0044241)
0.0 0.5 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.2 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.0 0.6 GO:0045116 protein neddylation(GO:0045116)
0.0 0.4 GO:0006857 oligopeptide transport(GO:0006857)
0.0 1.0 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 1.2 GO:0034112 positive regulation of homotypic cell-cell adhesion(GO:0034112) positive regulation of T cell activation(GO:0050870) positive regulation of leukocyte cell-cell adhesion(GO:1903039)
0.0 0.4 GO:0021694 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.0 0.3 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.0 0.8 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.2 GO:0021680 cerebellar Purkinje cell layer development(GO:0021680)
0.0 0.6 GO:0015693 magnesium ion transport(GO:0015693)
0.0 1.3 GO:0001676 long-chain fatty acid metabolic process(GO:0001676)
0.0 0.2 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.2 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 1.0 GO:0055092 cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
0.0 0.1 GO:0072116 kidney rudiment formation(GO:0072003) pronephros formation(GO:0072116)
0.0 0.6 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.0 0.2 GO:2000479 regulation of cAMP-dependent protein kinase activity(GO:2000479)
0.0 0.4 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.6 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.0 2.0 GO:0044744 protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744) single-organism nuclear import(GO:1902593)
0.0 0.1 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 0.3 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.0 0.2 GO:0035677 posterior lateral line neuromast hair cell development(GO:0035677)
0.0 0.9 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.0 0.6 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.2 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 0.2 GO:0021627 olfactory nerve development(GO:0021553) olfactory nerve morphogenesis(GO:0021627) olfactory nerve formation(GO:0021628)
0.0 0.8 GO:0051307 meiotic chromosome separation(GO:0051307)
0.0 0.5 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.0 0.4 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.4 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.0 0.2 GO:0072506 phosphate ion homeostasis(GO:0055062) trivalent inorganic anion homeostasis(GO:0072506)
0.0 0.4 GO:0007339 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.0 0.2 GO:0031048 chromatin silencing by small RNA(GO:0031048)
0.0 0.1 GO:0042766 nucleosome mobilization(GO:0042766)
0.0 0.1 GO:0048260 positive regulation of receptor-mediated endocytosis(GO:0048260) protein localization to early endosome(GO:1902946)
0.0 0.2 GO:0035108 limb morphogenesis(GO:0035108)
0.0 0.1 GO:0035678 neuromast hair cell morphogenesis(GO:0035678)
0.0 0.4 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 0.2 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.0 1.0 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 1.2 GO:0031047 gene silencing by RNA(GO:0031047)
0.0 0.0 GO:1903792 negative regulation of anion transport(GO:1903792)
0.0 0.2 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.0 0.4 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.0 0.1 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.0 0.3 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208)
0.0 0.1 GO:1901387 positive regulation of voltage-gated calcium channel activity(GO:1901387)
0.0 1.0 GO:0051028 mRNA transport(GO:0051028)
0.0 0.6 GO:0030261 chromosome condensation(GO:0030261)
0.0 0.6 GO:0045104 intermediate filament-based process(GO:0045103) intermediate filament cytoskeleton organization(GO:0045104)
0.0 0.5 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.1 GO:2000178 negative regulation of neural precursor cell proliferation(GO:2000178)
0.0 0.3 GO:0072663 protein targeting to peroxisome(GO:0006625) peroxisomal transport(GO:0043574) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.0 0.2 GO:0098962 regulation of postsynaptic neurotransmitter receptor activity(GO:0098962)
0.0 0.5 GO:0016525 negative regulation of angiogenesis(GO:0016525)
0.0 0.5 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.1 GO:0032917 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.0 0.3 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.3 GO:0048634 regulation of muscle organ development(GO:0048634)
0.0 0.1 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.0 0.2 GO:0014066 regulation of phosphatidylinositol 3-kinase signaling(GO:0014066)
0.0 0.1 GO:0030520 intracellular estrogen receptor signaling pathway(GO:0030520)
0.0 0.6 GO:0009948 anterior/posterior axis specification(GO:0009948)
0.0 0.3 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 0.5 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800)
0.0 0.1 GO:0072393 microtubule anchoring at microtubule organizing center(GO:0072393)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0043291 RAVE complex(GO:0043291)
0.2 2.5 GO:0045095 keratin filament(GO:0045095)
0.2 1.0 GO:0008091 spectrin(GO:0008091)
0.2 0.5 GO:0070578 RISC-loading complex(GO:0070578)
0.1 0.6 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.1 0.4 GO:0031213 RSF complex(GO:0031213)
0.1 0.5 GO:0035339 SPOTS complex(GO:0035339)
0.1 0.3 GO:0034456 CURI complex(GO:0032545) UTP-C complex(GO:0034456)
0.1 1.0 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.1 0.5 GO:0005899 insulin receptor complex(GO:0005899)
0.1 0.6 GO:0019008 molybdopterin synthase complex(GO:0019008)
0.1 0.2 GO:1990745 EARP complex(GO:1990745)
0.1 0.3 GO:0070209 ASTRA complex(GO:0070209)
0.1 0.4 GO:0031262 Ndc80 complex(GO:0031262)
0.1 0.4 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.1 0.4 GO:0000138 Golgi trans cisterna(GO:0000138)
0.1 0.5 GO:0070652 HAUS complex(GO:0070652)
0.1 0.4 GO:0005663 DNA replication factor C complex(GO:0005663)
0.1 2.5 GO:0005657 replication fork(GO:0005657)
0.0 3.3 GO:0030173 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 0.8 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.2 GO:0000243 commitment complex(GO:0000243)
0.0 0.2 GO:0070876 SOSS complex(GO:0070876)
0.0 0.2 GO:0070062 extracellular exosome(GO:0070062)
0.0 0.5 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.8 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.3 GO:0016586 RSC complex(GO:0016586)
0.0 1.2 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.7 GO:0005685 U1 snRNP(GO:0005685)
0.0 1.5 GO:0005811 lipid particle(GO:0005811)
0.0 0.3 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 0.4 GO:0030315 T-tubule(GO:0030315)
0.0 0.2 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 1.0 GO:0016605 PML body(GO:0016605)
0.0 0.3 GO:0000177 nuclear exosome (RNase complex)(GO:0000176) cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.4 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.9 GO:0031970 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 1.5 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.4 GO:0005771 multivesicular body(GO:0005771)
0.0 0.4 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.6 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.9 GO:0072686 mitotic spindle(GO:0072686)
0.0 1.1 GO:0055037 recycling endosome(GO:0055037)
0.0 0.2 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.1 GO:0031010 ISWI-type complex(GO:0031010)
0.0 0.1 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.3 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 1.6 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.9 GO:0032432 actin filament bundle(GO:0032432)
0.0 1.1 GO:0098791 Golgi stack(GO:0005795) Golgi subcompartment(GO:0098791)
0.0 1.1 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 1.4 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.1 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.7 GO:0030139 endocytic vesicle(GO:0030139)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:0008761 UDP-N-acetylglucosamine 2-epimerase activity(GO:0008761) N-acylmannosamine kinase activity(GO:0009384)
0.6 2.2 GO:0051059 NF-kappaB binding(GO:0051059)
0.5 2.5 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.4 1.2 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.3 0.9 GO:0004394 heparan sulfate 2-O-sulfotransferase activity(GO:0004394)
0.3 1.1 GO:0052654 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.3 1.0 GO:0071253 connexin binding(GO:0071253)
0.2 1.0 GO:0004558 alpha-1,4-glucosidase activity(GO:0004558)
0.2 0.5 GO:0071532 ankyrin repeat binding(GO:0071532)
0.2 0.9 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.1 0.6 GO:0030366 molybdopterin synthase activity(GO:0030366)
0.1 0.4 GO:0061513 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.1 0.7 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.1 0.5 GO:0070883 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296) pre-miRNA binding(GO:0070883)
0.1 2.1 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 0.6 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.1 1.0 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.1 0.6 GO:1990756 protein binding, bridging involved in substrate recognition for ubiquitination(GO:1990756)
0.1 0.5 GO:0005009 insulin-activated receptor activity(GO:0005009) insulin receptor substrate binding(GO:0043560)
0.1 0.9 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.1 0.4 GO:0033857 inositol heptakisphosphate kinase activity(GO:0000829) diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.1 0.6 GO:0030274 LIM domain binding(GO:0030274)
0.1 0.4 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.1 1.2 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1 0.7 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.1 0.4 GO:0034431 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.1 0.7 GO:0030619 U1 snRNA binding(GO:0030619)
0.1 1.8 GO:0015299 solute:proton antiporter activity(GO:0015299)
0.1 1.3 GO:0019211 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.1 0.6 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.1 0.6 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.1 0.2 GO:0016436 rRNA (uridine) methyltransferase activity(GO:0016436)
0.1 0.2 GO:0003844 1,4-alpha-glucan branching enzyme activity(GO:0003844)
0.1 1.1 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 1.3 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0 0.3 GO:0097363 protein O-GlcNAc transferase activity(GO:0097363)
0.0 0.7 GO:0019870 chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.0 0.9 GO:0016251 obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.0 0.5 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.8 GO:0002039 p53 binding(GO:0002039)
0.0 0.6 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.4 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.8 GO:0070411 I-SMAD binding(GO:0070411)
0.0 2.2 GO:0061650 ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.0 0.2 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0 0.4 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.4 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.5 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.6 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.8 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.6 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.2 GO:0035252 UDP-xylosyltransferase activity(GO:0035252)
0.0 0.1 GO:0016920 pyroglutamyl-peptidase activity(GO:0016920)
0.0 0.5 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.5 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.3 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.2 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.3 GO:0031995 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
0.0 0.5 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.3 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.4 GO:0032190 acrosin binding(GO:0032190)
0.0 0.7 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.1 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.3 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.5 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.3 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 1.0 GO:0032813 tumor necrosis factor receptor superfamily binding(GO:0032813)
0.0 1.3 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.4 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.4 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 1.7 GO:0045296 cadherin binding(GO:0045296)
0.0 0.4 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.4 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.1 GO:0031843 neuropeptide Y receptor binding(GO:0031841) type 2 neuropeptide Y receptor binding(GO:0031843)
0.0 0.4 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.1 GO:0038064 protein tyrosine kinase collagen receptor activity(GO:0038062) collagen receptor activity(GO:0038064)
0.0 0.1 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.4 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 2.4 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.1 GO:0034452 dynactin binding(GO:0034452)
0.0 0.1 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.5 GO:0019003 GDP binding(GO:0019003)
0.0 0.1 GO:1903924 estradiol binding(GO:1903924)
0.0 0.1 GO:0019808 polyamine binding(GO:0019808) spermidine binding(GO:0019809)
0.0 0.3 GO:0031267 small GTPase binding(GO:0031267)
0.0 0.5 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.0 0.7 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 0.5 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 1.0 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.4 GO:0035014 phosphatidylinositol 3-kinase regulator activity(GO:0035014)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 1.8 PID AURORA B PATHWAY Aurora B signaling
0.0 3.2 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 2.0 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.6 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.6 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 1.0 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.4 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 1.4 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 1.6 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.9 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.6 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.4 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.8 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.7 PID FOXO PATHWAY FoxO family signaling
0.0 0.6 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.4 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.3 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.1 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.4 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.4 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 1.9 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.4 PID ATR PATHWAY ATR signaling pathway
0.0 0.3 ST JNK MAPK PATHWAY JNK MAPK Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 1.0 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 1.5 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.1 0.9 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 1.1 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 0.8 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.1 1.0 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.7 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.9 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.0 0.1 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0 0.5 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.4 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.5 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 1.1 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.3 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.4 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.0 0.1 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.5 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.2 REACTOME PRE NOTCH EXPRESSION AND PROCESSING Genes involved in Pre-NOTCH Expression and Processing
0.0 0.3 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.9 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.7 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.6 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.6 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 0.3 REACTOME KINESINS Genes involved in Kinesins
0.0 0.1 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.1 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex