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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for nfil3-4+si:dkey-172o19.2

Z-value: 1.04

Motif logo

Transcription factors associated with nfil3-4+si:dkey-172o19.2

Gene Symbol Gene ID Gene Info
ENSDARG00000071398 si_dkey-172o19.2
ENSDARG00000092346 nuclear factor, interleukin 3 regulated, member 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nfil3-4dr11_v1_chr22_+_20560041_205600410.663.0e-03Click!
si:dkey-172o19.2dr11_v1_chr22_+_20546612_205466120.644.5e-03Click!

Activity profile of nfil3-4+si:dkey-172o19.2 motif

Sorted Z-values of nfil3-4+si:dkey-172o19.2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr9_-_1702648 3.64 ENSDART00000102934
heterogeneous nuclear ribonucleoprotein A3
chr25_-_19584735 3.47 ENSDART00000137930
synaptonemal complex protein 3
chr22_-_15562933 3.39 ENSDART00000141528
ankyrin repeat and MYND domain containing 1
chr25_-_19585010 3.08 ENSDART00000021340
synaptonemal complex protein 3
chr12_-_23128746 3.00 ENSDART00000170018
armadillo repeat containing 4
chr24_-_26310854 2.96 ENSDART00000080113
apolipoprotein Db
chr16_+_34523515 2.92 ENSDART00000041007
stathmin 1b
chr9_-_48736388 2.91 ENSDART00000022074
dehydrogenase/reductase (SDR family) member 9
chr16_+_43139504 2.86 ENSDART00000065643
DBF4 zinc finger
chr5_-_41494831 2.75 ENSDART00000051081
eukaryotic translation elongation factor 2, like 2
chr4_+_3389866 2.61 ENSDART00000153834
synaptophysin-like 1
chr23_+_27352072 2.59 ENSDART00000144762
si:dkey-9p24.5
chr18_+_7456597 2.55 ENSDART00000142270
telomere repeat binding bouquet formation protein 1
chr13_+_502230 2.50 ENSDART00000013007
delta(4)-desaturase, sphingolipid 1
chr23_+_27345826 2.49 ENSDART00000132635
transmembrane (C-terminal) protease, serine 12
chr15_-_20939579 2.49 ENSDART00000152371
ubiquitin specific peptidase 2a
chr12_+_46960579 2.48 ENSDART00000149032
ornithine aminotransferase
chr16_-_29557338 2.41 ENSDART00000058888
HORMA domain containing 1
chr7_-_10560964 2.41 ENSDART00000172761
ENSDART00000170476
5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
chr15_-_4969525 2.40 ENSDART00000157223
lipoyl(octanoyl) transferase 2
chr23_-_23401305 2.35 ENSDART00000078936
hairy-related 9
chr16_-_45069882 2.33 ENSDART00000058384
glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
chr15_+_44053244 2.31 ENSDART00000059550
leucine rich repeat containing 51
chr4_-_72544805 2.30 ENSDART00000110261
zgc:175107
chr22_-_21314821 2.28 ENSDART00000105546
ENSDART00000135388
CDC28 protein kinase regulatory subunit 2
chr20_+_29743904 2.25 ENSDART00000146366
ENSDART00000153154
kinase D-interacting substrate 220b
chr5_-_36949476 2.20 ENSDART00000047269
H3 histone, family 3C
chr3_+_24458204 2.19 ENSDART00000155028
ENSDART00000153551
chromobox homolog 6b
chr10_+_6625785 2.19 ENSDART00000148433
si:ch211-57m13.3
chr12_-_46959990 2.15 ENSDART00000084557
phospholysine phosphohistidine inorganic pyrophosphate phosphatase
chr1_+_57311901 2.14 ENSDART00000149397
mycbp associated protein
chr4_-_12914163 2.13 ENSDART00000140002
ENSDART00000145917
ENSDART00000141355
ENSDART00000067135
methionine sulfoxide reductase B3
chr11_-_44876005 2.12 ENSDART00000192006
opsin 6, group member a
chr19_+_46259619 2.11 ENSDART00000158032
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1a (glutamate binding)
chr5_-_13564961 2.06 ENSDART00000146827
si:ch211-230g14.3
chr7_-_24364536 2.06 ENSDART00000064789
thioredoxin
chr18_+_7456888 2.01 ENSDART00000081468
telomere repeat binding bouquet formation protein 1
chr21_+_22423286 1.99 ENSDART00000133190
calcyphosine-like b
chr10_+_6641514 1.95 ENSDART00000150003
si:ch211-57m13.5
chr20_-_42750271 1.92 ENSDART00000132208
tubulin tyrosine ligase-like family, member 2
chr4_-_13567387 1.92 ENSDART00000132971
ENSDART00000102010
Mdm1 nuclear protein homolog (mouse)
chr6_-_19683406 1.88 ENSDART00000158041
cilia and flagella associated protein 52
chr15_+_4969128 1.88 ENSDART00000062856
ring finger protein 169
chr17_-_20979077 1.87 ENSDART00000006676
phytanoyl-CoA 2-hydroxylase interacting protein-like a
chr5_-_3118346 1.84 ENSDART00000167554
heat shock transcription factor family member 5
chr24_-_26328721 1.81 ENSDART00000125468
apolipoprotein Db
chr5_-_36948586 1.80 ENSDART00000193606
H3 histone, family 3C
chr3_-_31783737 1.80 ENSDART00000090809
potassium voltage-gated channel, subfamily H (eag-related), member 6a
chr6_+_48348415 1.78 ENSDART00000064826
Mov10 RISC complex RNA helicase a
chr22_+_1796057 1.77 ENSDART00000170834
zinc finger protein 1179
chr18_+_402048 1.76 ENSDART00000166345
glucose-6-phosphate isomerase b
chr21_-_22114625 1.74 ENSDART00000177426
ENSDART00000135410
ELMO/CED-12 domain containing 1
chr12_-_23129453 1.74 ENSDART00000077453
armadillo repeat containing 4
chr11_-_38899816 1.74 ENSDART00000141515
Pim proto-oncogene, serine/threonine kinase, related 127
chr20_+_1121458 1.73 ENSDART00000064472
proline-rich nuclear receptor coactivator 1
chr11_-_24681292 1.72 ENSDART00000089601
olfactomedin-like 3b
chr10_+_39091353 1.71 ENSDART00000125986
si:ch73-1a9.4
chr20_-_26551210 1.71 ENSDART00000077715
si:dkey-25e12.3
chr15_-_1031511 1.70 ENSDART00000153569
si:dkey-77f5.4
chr13_+_32446169 1.70 ENSDART00000143325
5'-nucleotidase, cytosolic IB a
chr17_-_43466317 1.69 ENSDART00000155313
heat shock protein 4 like
chr5_-_69523816 1.69 ENSDART00000112692
si:ch211-157p22.10
chr1_+_50538839 1.67 ENSDART00000020412
polycystic kidney disease 2
chr19_-_41069573 1.66 ENSDART00000111982
ENSDART00000193142
sarcoglycan, epsilon
chr18_-_44285539 1.66 ENSDART00000137222
Pim proto-oncogene, serine/threonine kinase, related 179
chr8_-_26918516 1.66 ENSDART00000008742
zinc finger, MYND-type containing 12
chr16_-_13818061 1.66 ENSDART00000132982
ENSDART00000144856
leukocyte receptor cluster (LRC) member 9
chr14_-_33360344 1.66 ENSDART00000181291
Pim proto-oncogene, serine/threonine kinase, related 117
chr5_+_67971627 1.65 ENSDART00000144879
mitochondrial translational initiation factor 3
chr8_-_11546175 1.65 ENSDART00000081909
si:ch211-248e11.2
chr12_+_26471712 1.64 ENSDART00000162115
nudE neurodevelopment protein 1-like 1a
chr17_+_12159529 1.64 ENSDART00000046802
saccharopine dehydrogenase a
chr19_+_44004348 1.61 ENSDART00000109425
naked cuticle homolog 3
chr7_-_59311165 1.61 ENSDART00000171105
meiosis 1 associated protein
chr2_-_2957970 1.60 ENSDART00000162505
si:ch1073-82l19.1
chr4_-_12725513 1.59 ENSDART00000132286
microsomal glutathione S-transferase 1.2
chr11_+_44356707 1.59 ENSDART00000165219
serine/arginine-rich splicing factor 7b
chr15_+_19838458 1.58 ENSDART00000101204
activated leukocyte cell adhesion molecule b
chr10_+_6697369 1.57 ENSDART00000148606
si:ch211-57m13.8
chr20_-_52631998 1.57 ENSDART00000145283
ENSDART00000139072
si:ch211-221n20.1
chr5_+_66353750 1.56 ENSDART00000143410
si:ch211-261c8.5
chr1_-_54158902 1.54 ENSDART00000193267

chr11_+_44356504 1.51 ENSDART00000160678
serine/arginine-rich splicing factor 7b
chr14_+_4151379 1.51 ENSDART00000160431
dehydrogenase/reductase (SDR family) member 13 like 1
chr17_-_5769196 1.47 ENSDART00000113885
si:dkey-100n19.2
chr23_+_24085531 1.47 ENSDART00000139710
tubulin tyrosine ligase-like family, member 10
chr20_-_25533739 1.46 ENSDART00000063064
cytochrome P450, family 2, subfamily AD, polypeptide 6
chr5_-_20185665 1.46 ENSDART00000051612
D-amino-acid oxidase, tandem duplicate 2
chr17_-_8268406 1.45 ENSDART00000149873
ENSDART00000064668
ENSDART00000148403
Abelson helper integration site 1
chr10_-_24371312 1.44 ENSDART00000149362
phosphatidylinositol transfer protein, alpha b
chr11_+_6295370 1.42 ENSDART00000139882
RAN binding protein 3a
chr8_-_49431939 1.42 ENSDART00000011453
ENSDART00000088240
ENSDART00000114173
synaptophysin b
chr5_+_42400777 1.42 ENSDART00000183114

chr4_-_16545085 1.42 ENSDART00000033188
B-cell translocation gene 1, anti-proliferative
chr14_+_33329761 1.42 ENSDART00000161138
sosondowah ankyrin repeat domain family d
chr19_+_43995936 1.41 ENSDART00000130483
naked cuticle homolog 3
chr5_-_15692030 1.40 ENSDART00000099545

chr10_+_6747720 1.40 ENSDART00000148571
si:ch211-57m13.10
chr17_-_48805159 1.39 ENSDART00000103662
kinesin family member 6
chr18_-_16922905 1.38 ENSDART00000187165
WEE1 G2 checkpoint kinase
chr19_+_43978814 1.37 ENSDART00000102314
naked cuticle homolog 3
chr8_-_13046089 1.37 ENSDART00000137784
si:dkey-208b23.5
chr10_+_26667475 1.37 ENSDART00000133281
ENSDART00000147013
si:ch73-52f15.5
chr7_+_8670398 1.37 ENSDART00000164195
si:ch211-1o7.2
chr1_-_35928942 1.37 ENSDART00000033566
SMAD family member 1
chr13_-_50672341 1.36 ENSDART00000190498

chr11_+_30161699 1.34 ENSDART00000190504
cyclin-dependent kinase-like 5
chr11_-_6265574 1.34 ENSDART00000181974
ENSDART00000104405
chemokine (C-C motif) ligand 25b
chr10_+_6664911 1.33 ENSDART00000148377
si:ch211-57m13.6
chr21_+_17956024 1.33 ENSDART00000142468
dynein, axonemal, intermediate chain 1, paralog 2
chr3_-_1204341 1.33 ENSDART00000089646
family with sequence similarity 234, member B
chr16_+_23398369 1.32 ENSDART00000037694
S100 calcium binding protein A10b
chr7_+_49695904 1.31 ENSDART00000183550
ENSDART00000126991
achaete-scute family bHLH transcription factor 1b
chr11_+_24900123 1.30 ENSDART00000044987
ENSDART00000148023
translocase of inner mitochondrial membrane 17 homolog A (yeast)
chr21_-_2955181 1.29 ENSDART00000158991
ENSDART00000174052
zinc finger protein 971
chr25_-_3469576 1.29 ENSDART00000186738
HMG-box transcription factor 1
chr12_+_7491690 1.27 ENSDART00000152564
phytanoyl-CoA 2-hydroxylase interacting protein-like b
chr7_+_26629084 1.27 ENSDART00000101044
ENSDART00000173765
heat shock factor binding protein 1a
chr24_+_5840258 1.26 ENSDART00000087034
transient receptor potential cation channel, subfamily C, member 1
chr7_-_19544330 1.26 ENSDART00000181659
si:ch211-212k18.11
chr23_-_19558556 1.26 ENSDART00000134012
dynein, axonemal, heavy chain 12
chr25_+_13731542 1.25 ENSDART00000161012
coiled-coil domain containing 135
chr22_-_18491813 1.24 ENSDART00000105419
si:ch211-212d10.2
chr12_-_45197038 1.24 ENSDART00000016635
BRCA2 and CDKN1A interacting protein
chr20_-_44496245 1.24 ENSDART00000012229
FK506 binding protein 1b
chr10_+_6681523 1.24 ENSDART00000148884
si:ch211-57m13.7
chr25_+_34845469 1.23 ENSDART00000145416
transmembrane protein 231
chr4_-_1015896 1.22 ENSDART00000170292
family with sequence similarity 180 member A
chr21_+_45366229 1.20 ENSDART00000029946
ubiquitin-conjugating enzyme E2B (RAD6 homolog)
chr17_+_14425219 1.19 ENSDART00000153994
coiled-coil domain containing 175
chr15_-_1022436 1.19 ENSDART00000156003
zinc finger protein 1010
chr15_+_37559570 1.18 ENSDART00000085522
heat shock protein, alpha-crystallin-related, b6
chr5_+_6955900 1.18 ENSDART00000099417

chr25_-_774350 1.17 ENSDART00000166321
ENSDART00000160386
interleukin 1 receptor associated kinase 4
chr8_+_2438638 1.17 ENSDART00000141263
si:ch211-220d9.3
chr22_+_20720808 1.17 ENSDART00000171321
si:dkey-211f22.5
chr1_-_46244523 1.17 ENSDART00000143908
si:ch211-138g9.3
chr16_-_39178979 1.16 ENSDART00000158894
si:dkey-99n20.6
chr19_+_3653976 1.16 ENSDART00000125673
neural precursor cell expressed, developmentally down-regulated 9
chr9_+_38712474 1.16 ENSDART00000182874
KAT8 regulatory NSL complex subunit 1-like
chr20_-_51697437 1.15 ENSDART00000145391
si:ch211-14a11.2
chr1_-_35929143 1.15 ENSDART00000185002
SMAD family member 1
chr7_+_52761841 1.15 ENSDART00000111444
diphosphoinositol pentakisphosphate kinase 1a
chr25_-_16600811 1.15 ENSDART00000011397
carboxypeptidase A2 (pancreatic)
chr18_-_41232297 1.15 ENSDART00000036928
F-box protein 36a
chr14_-_34512859 1.14 ENSDART00000140368
si:ch211-232m8.3
chr22_-_15593824 1.14 ENSDART00000123125
tropomyosin 4a
chr20_-_32007209 1.14 ENSDART00000021575
androglobin
chr20_-_43436896 1.13 ENSDART00000144697
Pim proto-oncogene, serine/threonine kinase, related 109
chr2_+_51645164 1.13 ENSDART00000169600
abhydrolase domain containing 4
chr4_-_17642168 1.12 ENSDART00000007030
kelch-like family, member 42
chr14_-_26400501 1.11 ENSDART00000054189
Pim proto-oncogene, serine/threonine kinase, related 212
chr18_+_26899316 1.10 ENSDART00000050230
tetraspanin 3a
chr5_-_26093945 1.10 ENSDART00000010199
ENSDART00000145096
family with sequence similarity 219, member Ab
chr23_-_19558263 1.10 ENSDART00000084477
ENSDART00000179748
ENSDART00000193127
dynein, axonemal, heavy chain 12
chr22_-_10110959 1.09 ENSDART00000031005
ENSDART00000147580
glutaminase 2b (liver, mitochondrial)
chr16_+_23397785 1.09 ENSDART00000148961
S100 calcium binding protein A10b
chr25_-_8602437 1.09 ENSDART00000171200
Rh family, C glycoprotein b
chr21_+_22845317 1.09 ENSDART00000065555
baculoviral IAP repeat containing 2
chr21_+_28496194 1.08 ENSDART00000138236
cytochrome c oxidase subunit VIIIA (ubiquitous)
chr6_+_49053319 1.08 ENSDART00000124524
synaptonemal complex protein 1
chr25_+_34845115 1.08 ENSDART00000061996
transmembrane protein 231
chr11_-_22372072 1.07 ENSDART00000065996
transmembrane protein 183A
chr3_-_24458281 1.07 ENSDART00000153993
BAI1-associated protein 2-like 2a
chr6_-_37469775 1.07 ENSDART00000156546
phosphatidylinositol-specific phospholipase C, X domain containing 1
chr25_+_35051656 1.06 ENSDART00000133379
histone cluster 2, H3c
chr4_+_2655358 1.06 ENSDART00000007638
B cell receptor associated protein 29
chr17_+_956821 1.06 ENSDART00000082101
protein phosphatase 2, regulatory subunit B', gamma a
chr19_-_33370271 1.05 ENSDART00000132628
naked cuticle homolog 3, like
chr3_-_16250527 1.05 ENSDART00000146699
ENSDART00000141181
branched chain keto acid dehydrogenase E1, beta polypeptide, like
chr17_-_17764801 1.05 ENSDART00000155261
SRA stem-loop interacting RNA binding protein
chr25_-_19443421 1.05 ENSDART00000067362
cocaine- and amphetamine-regulated transcript 2
chr1_+_9994811 1.04 ENSDART00000143719
ENSDART00000110749
si:dkeyp-75b4.10
chr22_+_10606573 1.04 ENSDART00000192638
RAD54 like 2
chr20_-_53981626 1.04 ENSDART00000023550
heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2
chr1_-_59411901 1.04 ENSDART00000167015
si:ch211-188p14.4
chr3_+_48234445 1.03 ENSDART00000161419
tubulin folding cofactor D
chr25_+_34014523 1.03 ENSDART00000182856
annexin A2a
chr20_+_25563105 1.03 ENSDART00000063100
cytochrome P450, family 2, subfamily P, polypeptide 6
chr5_-_26181863 1.03 ENSDART00000098500
coiled-coil domain containing 125
chr12_-_5120339 1.02 ENSDART00000168759
retinol binding protein 4, plasma
chr8_-_41228530 1.02 ENSDART00000165949
ENSDART00000173055
fumarylacetoacetate hydrolase domain containing 2A
chr13_-_10730056 1.01 ENSDART00000126725
protein phosphatase, Mg2+/Mn2+ dependent, 1Ba
chr22_+_35472653 1.01 ENSDART00000076424
ENSDART00000187204
Tctex1 domain containing 2
chr1_-_10071422 1.01 ENSDART00000135522
ENSDART00000033118
fibrinogen alpha chain
chr20_-_40717900 1.00 ENSDART00000181663
connexin 43
chr5_-_26199505 1.00 ENSDART00000132950
RAD17 checkpoint clamp loader component
chr16_+_40576679 1.00 ENSDART00000169412
ENSDART00000193464
cyclin E2
chr25_+_14398650 0.99 ENSDART00000130548
cytokine induced apoptosis inhibitor 1
chr19_-_23895839 0.99 ENSDART00000174834
si:dkey-222b8.4
chr2_+_9061885 0.99 ENSDART00000028906
phosphatidylinositol glycan anchor biosynthesis, class K
chr7_-_12968689 0.99 ENSDART00000173115
ENSDART00000013690
ribosomal protein, large P2, like
chr4_-_14915268 0.98 ENSDART00000067040
si:dkey-180p18.9
chr15_+_44208464 0.98 ENSDART00000126868

chr11_-_41130239 0.97 ENSDART00000173268
DnaJ (Hsp40) homolog, subfamily C, member 11b
chr15_-_40065265 0.97 ENSDART00000063781
ENSDART00000142394
G protein-coupled receptor 55a
chr20_-_1314355 0.97 ENSDART00000152436
protein-L-isoaspartate (D-aspartate) O-methyltransferase
chr17_+_1323699 0.97 ENSDART00000172540
adenylosuccinate synthase like 1
chr1_-_51606552 0.96 ENSDART00000130828
cannabinoid receptor interacting protein 1a
chr20_+_25586099 0.96 ENSDART00000063122
ENSDART00000134047
cytochrome P450, family 2, subfamily P, polypeptide 10

Network of associatons between targets according to the STRING database.

First level regulatory network of nfil3-4+si:dkey-172o19.2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 4.6 GO:0044821 telomere localization(GO:0034397) telomere tethering at nuclear periphery(GO:0034398) meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic telomere clustering(GO:0045141) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome localization to nuclear envelope involved in homologous chromosome segregation(GO:0090220) chromosome attachment to the nuclear envelope(GO:0097240)
0.8 2.4 GO:0060631 regulation of meiosis I(GO:0060631)
0.8 2.4 GO:2000376 oxygen metabolic process(GO:0072592) regulation of oxygen metabolic process(GO:2000374) positive regulation of oxygen metabolic process(GO:2000376)
0.6 1.7 GO:0071498 cellular response to fluid shear stress(GO:0071498)
0.5 2.1 GO:0030091 protein repair(GO:0030091)
0.5 3.6 GO:2000105 positive regulation of DNA-dependent DNA replication(GO:2000105)
0.5 1.4 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.5 1.8 GO:0099625 regulation of membrane repolarization(GO:0060306) regulation of ventricular cardiac muscle cell membrane repolarization(GO:0060307) regulation of cardiac muscle cell membrane repolarization(GO:0099623) ventricular cardiac muscle cell membrane repolarization(GO:0099625)
0.4 1.3 GO:2000471 regulation of hematopoietic stem cell migration(GO:2000471)
0.4 1.7 GO:0046144 alanine metabolic process(GO:0006522) alanine catabolic process(GO:0006524) pyruvate family amino acid metabolic process(GO:0009078) pyruvate family amino acid catabolic process(GO:0009080) D-alanine family amino acid metabolic process(GO:0046144) D-alanine metabolic process(GO:0046436) D-alanine catabolic process(GO:0055130)
0.4 2.5 GO:0006788 heme oxidation(GO:0006788)
0.4 1.1 GO:0051026 meiotic DNA repair synthesis(GO:0000711) chiasma assembly(GO:0051026)
0.3 1.6 GO:0007060 male meiosis chromosome segregation(GO:0007060)
0.3 2.1 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.3 3.9 GO:0042572 retinol metabolic process(GO:0042572)
0.3 0.9 GO:0042364 water-soluble vitamin biosynthetic process(GO:0042364)
0.3 0.6 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500) protein localization to ciliary membrane(GO:1903441)
0.3 2.5 GO:0055129 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.3 1.9 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.3 1.6 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.3 1.1 GO:0060547 negative regulation of necroptotic process(GO:0060546) negative regulation of necrotic cell death(GO:0060547)
0.3 0.8 GO:0045579 positive regulation of B cell differentiation(GO:0045579)
0.3 1.0 GO:0070199 establishment of protein localization to chromosome(GO:0070199) establishment of protein localization to chromatin(GO:0071169)
0.2 1.2 GO:0090527 actin filament reorganization(GO:0090527)
0.2 1.6 GO:0046864 retinol transport(GO:0034633) isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865)
0.2 1.6 GO:0021885 forebrain cell migration(GO:0021885)
0.2 0.9 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.2 0.9 GO:0032790 ribosome disassembly(GO:0032790)
0.2 0.9 GO:0060468 negative regulation of fertilization(GO:0060467) prevention of polyspermy(GO:0060468) cortical granule exocytosis(GO:0060471)
0.2 6.5 GO:0007286 spermatid development(GO:0007286)
0.2 1.1 GO:0097272 ammonia homeostasis(GO:0097272)
0.2 1.1 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.2 1.1 GO:0046677 response to antibiotic(GO:0046677)
0.2 1.0 GO:1902369 negative regulation of RNA catabolic process(GO:1902369)
0.2 1.5 GO:1990845 adaptive thermogenesis(GO:1990845)
0.2 0.6 GO:0015695 organic cation transport(GO:0015695)
0.2 0.6 GO:2000434 regulation of protein neddylation(GO:2000434)
0.2 1.1 GO:0006572 tyrosine catabolic process(GO:0006572)
0.2 1.2 GO:0071941 nitrogen cycle metabolic process(GO:0071941)
0.2 1.0 GO:2000576 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.2 0.7 GO:0070316 G0 to G1 transition(GO:0045023) regulation of G0 to G1 transition(GO:0070316) negative regulation of G0 to G1 transition(GO:0070317)
0.2 0.7 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.2 1.6 GO:0032099 negative regulation of response to food(GO:0032096) negative regulation of appetite(GO:0032099)
0.2 0.5 GO:0071586 CAAX-box protein processing(GO:0071586) CAAX-box protein maturation(GO:0080120)
0.2 1.0 GO:0031116 positive regulation of microtubule polymerization(GO:0031116)
0.2 1.2 GO:0006662 glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904)
0.2 1.2 GO:0006537 glutamate biosynthetic process(GO:0006537) glutamine catabolic process(GO:0006543)
0.1 4.8 GO:0007568 aging(GO:0007568)
0.1 0.7 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.1 1.6 GO:1902108 regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902108)
0.1 1.5 GO:0044458 motile cilium assembly(GO:0044458)
0.1 1.3 GO:0030719 P granule organization(GO:0030719)
0.1 0.5 GO:1904184 regulation of pyruvate dehydrogenase activity(GO:1904182) positive regulation of pyruvate dehydrogenase activity(GO:1904184)
0.1 0.7 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.1 1.5 GO:0034694 response to prostaglandin(GO:0034694)
0.1 1.1 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.1 2.5 GO:0018095 protein polyglutamylation(GO:0018095)
0.1 1.7 GO:2000780 negative regulation of DNA repair(GO:0045738) negative regulation of double-strand break repair(GO:2000780)
0.1 2.9 GO:0045773 positive regulation of axon extension(GO:0045773)
0.1 1.0 GO:0099514 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.1 0.1 GO:0051792 medium-chain fatty acid biosynthetic process(GO:0051792)
0.1 0.8 GO:0015862 uridine transport(GO:0015862) pyrimidine nucleoside transport(GO:0015864)
0.1 0.4 GO:0097435 fibril organization(GO:0097435)
0.1 1.3 GO:0034605 cellular response to heat(GO:0034605)
0.1 1.6 GO:0046085 adenosine metabolic process(GO:0046085)
0.1 0.9 GO:0016139 glycoside metabolic process(GO:0016137) glycoside catabolic process(GO:0016139)
0.1 1.0 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.1 0.4 GO:0071305 cellular response to vitamin D(GO:0071305)
0.1 0.6 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.1 0.8 GO:0000076 DNA replication checkpoint(GO:0000076)
0.1 0.2 GO:0032570 response to progesterone(GO:0032570)
0.1 0.8 GO:0035776 intraciliary transport involved in cilium morphogenesis(GO:0035735) pronephric proximal tubule development(GO:0035776)
0.1 0.7 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.1 0.4 GO:0035777 pronephric distal tubule development(GO:0035777)
0.1 1.7 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 0.5 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.1 0.3 GO:0034088 maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.1 1.0 GO:2000272 negative regulation of receptor activity(GO:2000272)
0.1 0.3 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.1 0.5 GO:0071881 adenylate cyclase-inhibiting adrenergic receptor signaling pathway(GO:0071881)
0.1 0.4 GO:0007412 axon target recognition(GO:0007412)
0.1 0.3 GO:1902175 regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902175) negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902176)
0.1 0.3 GO:0006089 lactate metabolic process(GO:0006089)
0.1 1.6 GO:0030317 sperm motility(GO:0030317)
0.1 0.4 GO:0003418 chondrocyte differentiation involved in endochondral bone morphogenesis(GO:0003413) growth plate cartilage chondrocyte differentiation(GO:0003418)
0.1 0.3 GO:0003156 regulation of organ formation(GO:0003156)
0.1 1.3 GO:0036158 outer dynein arm assembly(GO:0036158)
0.1 0.5 GO:0098535 de novo centriole assembly(GO:0098535)
0.1 0.3 GO:0042256 mature ribosome assembly(GO:0042256)
0.1 0.3 GO:0006004 fucose metabolic process(GO:0006004)
0.1 0.4 GO:0034146 toll-like receptor 5 signaling pathway(GO:0034146)
0.1 2.3 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.1 1.0 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.1 0.3 GO:0010633 negative regulation of epithelial cell migration(GO:0010633)
0.1 0.3 GO:1901890 positive regulation of cell junction assembly(GO:1901890)
0.1 0.8 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.1 0.3 GO:0070857 regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251)
0.1 0.4 GO:0003210 cardiac atrium formation(GO:0003210)
0.1 4.5 GO:0042737 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.1 0.4 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.1 0.6 GO:1990511 piRNA biosynthetic process(GO:1990511)
0.1 0.9 GO:0042989 sequestering of actin monomers(GO:0042989)
0.1 1.1 GO:0006020 inositol metabolic process(GO:0006020)
0.1 0.5 GO:0060420 regulation of heart growth(GO:0060420)
0.1 2.2 GO:0007007 inner mitochondrial membrane organization(GO:0007007)
0.1 0.3 GO:0032207 regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208)
0.1 0.5 GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.1 0.2 GO:0016056 rhodopsin mediated signaling pathway(GO:0016056)
0.1 1.7 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.1 1.0 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.1 0.5 GO:0006574 valine catabolic process(GO:0006574)
0.1 0.3 GO:0070166 enamel mineralization(GO:0070166)
0.1 1.3 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.1 0.7 GO:0010887 negative regulation of cholesterol storage(GO:0010887)
0.1 4.9 GO:0006096 glycolytic process(GO:0006096)
0.1 0.4 GO:0036372 opsin transport(GO:0036372)
0.1 0.4 GO:0042362 fat-soluble vitamin biosynthetic process(GO:0042362)
0.1 1.0 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.1 0.7 GO:0098869 response to superoxide(GO:0000303) response to oxygen radical(GO:0000305) removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.1 1.1 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654) phosphatidic acid metabolic process(GO:0046473)
0.1 0.3 GO:0032289 central nervous system myelin formation(GO:0032289)
0.1 0.3 GO:0006560 proline metabolic process(GO:0006560)
0.1 0.4 GO:0071908 determination of intestine left/right asymmetry(GO:0071908)
0.1 0.7 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.1 0.2 GO:0002522 leukocyte migration involved in immune response(GO:0002522)
0.1 0.4 GO:1900744 regulation of p38MAPK cascade(GO:1900744)
0.1 0.4 GO:0003151 outflow tract morphogenesis(GO:0003151)
0.1 0.7 GO:1902041 regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902041) negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042)
0.1 0.3 GO:0010896 regulation of triglyceride catabolic process(GO:0010896) positive regulation of triglyceride catabolic process(GO:0010898)
0.1 2.2 GO:0044243 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.1 0.3 GO:0090230 regulation of centromere complex assembly(GO:0090230) regulation of kinetochore assembly(GO:0090234)
0.1 1.4 GO:1990798 pancreas regeneration(GO:1990798)
0.1 0.3 GO:0010481 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.1 0.5 GO:0032488 Cdc42 protein signal transduction(GO:0032488)
0.1 0.4 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.1 0.5 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.1 0.2 GO:0019628 urate catabolic process(GO:0019628) urate metabolic process(GO:0046415)
0.1 0.3 GO:0006031 chitin biosynthetic process(GO:0006031) glucosamine-containing compound biosynthetic process(GO:1901073)
0.1 0.2 GO:0014826 regulation of systemic arterial blood pressure by endothelin(GO:0003100) vein smooth muscle contraction(GO:0014826) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.1 3.8 GO:0006414 translational elongation(GO:0006414)
0.1 0.9 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.1 0.4 GO:0070285 pigment cell development(GO:0070285)
0.1 0.6 GO:0006611 protein export from nucleus(GO:0006611)
0.1 0.2 GO:1901295 negative regulation of striated muscle cell differentiation(GO:0051154) negative regulation of cardiac muscle tissue development(GO:0055026) cardiac muscle cell fate commitment(GO:0060923) canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:0061317) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901296) negative regulation of cardiocyte differentiation(GO:1905208) negative regulation of cardiac muscle cell differentiation(GO:2000726)
0.1 1.1 GO:0034453 microtubule anchoring(GO:0034453)
0.1 1.2 GO:0048168 regulation of neuronal synaptic plasticity(GO:0048168)
0.1 20.3 GO:0046777 protein autophosphorylation(GO:0046777)
0.1 0.4 GO:0060221 retinal rod cell differentiation(GO:0060221)
0.1 2.6 GO:0007019 microtubule depolymerization(GO:0007019)
0.1 0.9 GO:0097324 melanocyte migration(GO:0097324)
0.1 0.2 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.1 0.7 GO:0042574 retinal metabolic process(GO:0042574)
0.1 0.4 GO:0000270 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 1.6 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.3 GO:0032728 interferon-beta production(GO:0032608) regulation of interferon-beta production(GO:0032648) positive regulation of interferon-beta production(GO:0032728)
0.0 1.1 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.3 GO:0010799 regulation of peptidyl-threonine phosphorylation(GO:0010799) negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.0 2.4 GO:0006119 oxidative phosphorylation(GO:0006119)
0.0 0.2 GO:0015868 intracellular nucleoside transport(GO:0015859) purine nucleoside transmembrane transport(GO:0015860) purine nucleotide transport(GO:0015865) ATP transport(GO:0015867) purine ribonucleotide transport(GO:0015868) adenine nucleotide transport(GO:0051503) mitochondrial ATP transmembrane transport(GO:1990544)
0.0 0.4 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.0 0.5 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.7 GO:0090382 phagosome maturation(GO:0090382)
0.0 0.4 GO:0006361 transcription initiation from RNA polymerase I promoter(GO:0006361)
0.0 0.2 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 1.2 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 1.2 GO:0016574 histone ubiquitination(GO:0016574)
0.0 0.3 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.0 2.2 GO:0007602 phototransduction(GO:0007602)
0.0 0.2 GO:0035627 ceramide transport(GO:0035627)
0.0 0.3 GO:1902624 positive regulation of neutrophil migration(GO:1902624)
0.0 0.6 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.0 0.5 GO:1990118 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.1 GO:0051876 pigment granule dispersal(GO:0051876)
0.0 3.6 GO:0071560 transforming growth factor beta receptor signaling pathway(GO:0007179) response to transforming growth factor beta(GO:0071559) cellular response to transforming growth factor beta stimulus(GO:0071560)
0.0 0.6 GO:0045807 positive regulation of endocytosis(GO:0045807)
0.0 1.2 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.5 GO:0007035 vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452)
0.0 0.2 GO:0061010 gall bladder development(GO:0061010)
0.0 0.4 GO:0000710 meiotic mismatch repair(GO:0000710)
0.0 0.1 GO:0009191 ribonucleoside diphosphate catabolic process(GO:0009191)
0.0 0.3 GO:0034501 protein localization to kinetochore(GO:0034501) protein localization to chromosome, centromeric region(GO:0071459)
0.0 2.9 GO:0070121 Kupffer's vesicle development(GO:0070121)
0.0 0.3 GO:0016237 lysosomal microautophagy(GO:0016237) piecemeal microautophagy of nucleus(GO:0034727) single-organism membrane invagination(GO:1902534)
0.0 0.6 GO:0044872 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.0 0.7 GO:0060079 excitatory postsynaptic potential(GO:0060079)
0.0 0.5 GO:0046051 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.0 2.3 GO:0003341 cilium movement(GO:0003341)
0.0 0.2 GO:0036268 swimming(GO:0036268)
0.0 0.5 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.6 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.0 0.2 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 0.1 GO:0045046 peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.0 0.2 GO:0035479 angioblast cell migration from lateral mesoderm to midline(GO:0035479)
0.0 0.1 GO:0006953 acute-phase response(GO:0006953)
0.0 0.4 GO:0036388 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.0 0.5 GO:0060997 dendritic spine morphogenesis(GO:0060997) dendritic spine organization(GO:0097061)
0.0 2.1 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.8 GO:0021984 adenohypophysis development(GO:0021984)
0.0 0.4 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0 0.1 GO:0070221 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.0 0.4 GO:0006513 protein monoubiquitination(GO:0006513)
0.0 0.2 GO:0089700 protein kinase D signaling(GO:0089700)
0.0 0.5 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 1.2 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.2 GO:1903170 negative regulation of calcium ion transmembrane transporter activity(GO:1901020) negative regulation of voltage-gated calcium channel activity(GO:1901386) negative regulation of calcium ion transmembrane transport(GO:1903170)
0.0 0.3 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560) protein to membrane docking(GO:0022615)
0.0 0.2 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.2 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.0 0.2 GO:0051454 pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.0 0.2 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0 0.3 GO:0051295 establishment of meiotic spindle localization(GO:0051295)
0.0 0.9 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0 0.2 GO:0006309 apoptotic DNA fragmentation(GO:0006309) cellular component disassembly involved in execution phase of apoptosis(GO:0006921) apoptotic nuclear changes(GO:0030262)
0.0 0.5 GO:0060078 regulation of postsynaptic membrane potential(GO:0060078)
0.0 0.7 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.4 GO:0006801 superoxide metabolic process(GO:0006801)
0.0 0.1 GO:0021693 cerebellar Purkinje cell layer structural organization(GO:0021693) cerebellar cortex structural organization(GO:0021698)
0.0 0.3 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.0 1.1 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 1.0 GO:0016126 sterol biosynthetic process(GO:0016126)
0.0 0.3 GO:0019226 transmission of nerve impulse(GO:0019226)
0.0 0.5 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.1 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.1 GO:0032402 melanosome transport(GO:0032402) pigment granule transport(GO:0051904)
0.0 0.2 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.4 GO:0016203 muscle attachment(GO:0016203)
0.0 1.0 GO:0002455 humoral immune response mediated by circulating immunoglobulin(GO:0002455) complement activation, classical pathway(GO:0006958)
0.0 0.1 GO:0019474 lysine catabolic process(GO:0006554) L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
0.0 0.1 GO:0006086 acetyl-CoA biosynthetic process from pyruvate(GO:0006086)
0.0 0.7 GO:0032482 Rab protein signal transduction(GO:0032482)
0.0 1.1 GO:0003014 renal system process(GO:0003014)
0.0 1.7 GO:0009612 response to mechanical stimulus(GO:0009612)
0.0 0.3 GO:0098508 endothelial to hematopoietic transition(GO:0098508)
0.0 0.3 GO:0051127 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 1.5 GO:0007283 spermatogenesis(GO:0007283)
0.0 0.2 GO:0034427 nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'(GO:0034427)
0.0 0.3 GO:0006805 xenobiotic metabolic process(GO:0006805)
0.0 1.3 GO:0030048 actin filament-based movement(GO:0030048)
0.0 0.1 GO:0005991 trehalose metabolic process(GO:0005991)
0.0 0.8 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.0 0.4 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 2.1 GO:0050768 negative regulation of neurogenesis(GO:0050768)
0.0 0.2 GO:0034340 response to type I interferon(GO:0034340) type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.0 0.2 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.4 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.3 GO:0009086 methionine biosynthetic process(GO:0009086)
0.0 1.7 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.0 0.4 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.4 GO:0051092 positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.0 0.2 GO:0030168 platelet activation(GO:0030168)
0.0 0.2 GO:0010889 regulation of sequestering of triglyceride(GO:0010889) positive regulation of sequestering of triglyceride(GO:0010890) sequestering of triglyceride(GO:0030730)
0.0 1.0 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.0 0.4 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.0 0.2 GO:0022401 desensitization of G-protein coupled receptor protein signaling pathway(GO:0002029) G-protein coupled receptor internalization(GO:0002031) negative adaptation of signaling pathway(GO:0022401) adaptation of signaling pathway(GO:0023058)
0.0 0.5 GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0006919)
0.0 0.2 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.7 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.0 0.3 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.0 0.7 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 0.2 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.2 GO:0019835 cytolysis(GO:0019835)
0.0 0.2 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.0 0.7 GO:0051966 regulation of synaptic transmission, glutamatergic(GO:0051966)
0.0 0.4 GO:0070593 dendrite self-avoidance(GO:0070593)
0.0 1.2 GO:0045666 positive regulation of neuron differentiation(GO:0045666)
0.0 0.2 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.0 0.2 GO:0021754 facial nucleus development(GO:0021754)
0.0 0.1 GO:0042664 negative regulation of endodermal cell fate specification(GO:0042664)
0.0 0.1 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.3 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 0.7 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 0.3 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.0 0.2 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.1 GO:0038203 TORC2 signaling(GO:0038203)
0.0 1.1 GO:0007224 smoothened signaling pathway(GO:0007224)
0.0 0.2 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.2 GO:0010257 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.6 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.3 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.0 0.2 GO:0010043 response to zinc ion(GO:0010043)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 2.9 GO:0032839 dendrite cytoplasm(GO:0032839)
0.3 2.4 GO:0036156 inner dynein arm(GO:0036156)
0.3 1.0 GO:0005577 fibrinogen complex(GO:0005577)
0.3 8.0 GO:0000795 synaptonemal complex(GO:0000795)
0.3 3.9 GO:0070187 telosome(GO:0070187)
0.3 1.0 GO:0098574 cytoplasmic side of lysosomal membrane(GO:0098574)
0.2 1.2 GO:0033503 HULC complex(GO:0033503)
0.2 1.7 GO:0016012 sarcoglycan complex(GO:0016012)
0.2 0.9 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.2 0.8 GO:0030896 checkpoint clamp complex(GO:0030896)
0.2 0.9 GO:0071439 clathrin complex(GO:0071439)
0.2 2.7 GO:0036038 MKS complex(GO:0036038)
0.2 0.5 GO:0043202 vacuolar lumen(GO:0005775) lysosomal lumen(GO:0043202)
0.2 0.5 GO:0098536 deuterosome(GO:0098536)
0.2 1.0 GO:0033181 plasma membrane proton-transporting V-type ATPase complex(GO:0033181)
0.2 2.3 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 0.4 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.1 0.7 GO:0045257 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.1 0.9 GO:0016234 inclusion body(GO:0016234)
0.1 3.3 GO:0044447 axoneme part(GO:0044447)
0.1 2.4 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 1.0 GO:0034464 BBSome(GO:0034464)
0.1 1.3 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.1 0.7 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.1 1.6 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.1 1.2 GO:0061617 MICOS complex(GO:0061617)
0.1 1.6 GO:0044545 NSL complex(GO:0044545)
0.1 0.3 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.1 0.8 GO:0016586 RSC complex(GO:0016586)
0.1 1.2 GO:0097431 mitotic spindle pole(GO:0097431)
0.1 1.9 GO:0045277 respiratory chain complex IV(GO:0045277)
0.1 1.6 GO:0005869 dynactin complex(GO:0005869)
0.1 1.0 GO:0000792 heterochromatin(GO:0000792)
0.1 1.4 GO:0030992 intraciliary transport particle B(GO:0030992)
0.1 0.3 GO:0044611 nuclear pore inner ring(GO:0044611)
0.1 1.6 GO:0097546 ciliary base(GO:0097546)
0.1 0.7 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 1.0 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 0.6 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 2.4 GO:0043186 P granule(GO:0043186)
0.1 0.2 GO:0005953 CAAX-protein geranylgeranyltransferase complex(GO:0005953)
0.1 0.5 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 0.3 GO:0016600 flotillin complex(GO:0016600)
0.1 0.6 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.1 1.1 GO:0043209 myelin sheath(GO:0043209)
0.1 0.2 GO:0034709 methylosome(GO:0034709)
0.1 4.4 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.1 0.2 GO:0005880 nuclear microtubule(GO:0005880)
0.1 0.7 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.1 0.5 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.1 0.8 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 0.6 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.2 GO:0097433 dense body(GO:0097433)
0.0 0.2 GO:0005883 neurofilament(GO:0005883)
0.0 0.2 GO:0055087 Ski complex(GO:0055087)
0.0 1.2 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.4 GO:0070069 cytochrome complex(GO:0070069)
0.0 0.2 GO:0019815 B cell receptor complex(GO:0019815)
0.0 0.5 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.3 GO:0030428 cell septum(GO:0030428)
0.0 0.9 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 2.0 GO:0005811 lipid particle(GO:0005811)
0.0 2.1 GO:0031514 motile cilium(GO:0031514)
0.0 1.1 GO:0035861 site of double-strand break(GO:0035861)
0.0 1.2 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 0.3 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
0.0 0.3 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.4 GO:0002102 podosome(GO:0002102)
0.0 1.9 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.5 GO:0043195 terminal bouton(GO:0043195)
0.0 0.2 GO:0070062 extracellular exosome(GO:0070062)
0.0 0.2 GO:0097648 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor heterodimeric complex(GO:0038039) G-protein coupled receptor complex(GO:0097648)
0.0 0.4 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 2.2 GO:0030427 site of polarized growth(GO:0030427)
0.0 1.3 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.2 GO:0033557 Slx1-Slx4 complex(GO:0033557)
0.0 1.4 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.4 GO:0042555 MCM complex(GO:0042555)
0.0 0.4 GO:0098843 postsynaptic endocytic zone(GO:0098843) postsynaptic endocytic zone membrane(GO:0098844)
0.0 0.5 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.1 GO:0071818 BAT3 complex(GO:0071818)
0.0 0.2 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 1.4 GO:0031902 late endosome membrane(GO:0031902)
0.0 1.9 GO:0005604 basement membrane(GO:0005604)
0.0 0.3 GO:0044306 axon terminus(GO:0043679) neuron projection terminus(GO:0044306)
0.0 0.5 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.3 GO:0031209 SCAR complex(GO:0031209)
0.0 0.9 GO:0030658 transport vesicle membrane(GO:0030658)
0.0 0.2 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.5 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.1 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0 0.8 GO:0005861 troponin complex(GO:0005861)
0.0 0.9 GO:0070469 respiratory chain(GO:0070469)
0.0 0.2 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.6 GO:0005901 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 0.2 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.5 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.0 0.3 GO:0031430 M band(GO:0031430)
0.0 17.4 GO:0005615 extracellular space(GO:0005615)
0.0 0.1 GO:1903561 extracellular organelle(GO:0043230) extracellular vesicle(GO:1903561)
0.0 0.5 GO:0005902 microvillus(GO:0005902)
0.0 0.5 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.1 GO:0032797 SMN complex(GO:0032797)
0.0 6.3 GO:0005576 extracellular region(GO:0005576)
0.0 0.1 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.4 GO:0033819 lipoyl(octanoyl) transferase activity(GO:0033819)
0.6 1.8 GO:0032574 5'-3' RNA helicase activity(GO:0032574)
0.6 2.3 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.5 2.2 GO:0101006 inorganic diphosphatase activity(GO:0004427) protein histidine phosphatase activity(GO:0101006)
0.5 1.9 GO:0048487 beta-tubulin binding(GO:0048487)
0.4 1.7 GO:0003884 D-amino-acid oxidase activity(GO:0003884)
0.4 2.5 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.4 2.9 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.4 2.1 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.3 1.0 GO:0047173 phosphatidylcholine-retinol O-acyltransferase activity(GO:0047173)
0.3 2.3 GO:0043035 chromatin insulator sequence binding(GO:0043035)
0.3 1.1 GO:0033857 inositol heptakisphosphate kinase activity(GO:0000829) diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.3 0.8 GO:0045174 glutathione dehydrogenase (ascorbate) activity(GO:0045174)
0.2 1.7 GO:0000254 C-4 methylsterol oxidase activity(GO:0000254)
0.2 1.6 GO:0034632 retinol transporter activity(GO:0034632)
0.2 1.3 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.2 1.4 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.2 1.6 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.2 0.6 GO:0070735 protein-glycine ligase activity(GO:0070735) tubulin-glycine ligase activity(GO:0070738)
0.2 0.9 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.2 1.4 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors(GO:0016661)
0.2 2.3 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.2 0.5 GO:0033897 ribonuclease T2 activity(GO:0033897)
0.2 1.2 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.2 1.0 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.2 1.5 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.2 2.9 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.1 0.4 GO:0001160 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.1 0.4 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.1 0.4 GO:0005499 vitamin D binding(GO:0005499)
0.1 0.7 GO:0016886 ligase activity, forming phosphoric ester bonds(GO:0016886)
0.1 1.9 GO:0070740 protein-glutamic acid ligase activity(GO:0070739) tubulin-glutamic acid ligase activity(GO:0070740)
0.1 0.5 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.1 0.7 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.1 0.7 GO:0008131 primary amine oxidase activity(GO:0008131)
0.1 1.2 GO:0004359 glutaminase activity(GO:0004359)
0.1 0.5 GO:0005463 UDP-glucuronic acid transmembrane transporter activity(GO:0005461) UDP-N-acetylgalactosamine transmembrane transporter activity(GO:0005463)
0.1 1.9 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.1 1.7 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.1 2.4 GO:0070411 I-SMAD binding(GO:0070411)
0.1 1.3 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1 0.6 GO:0031852 mu-type opioid receptor binding(GO:0031852) dopamine receptor binding(GO:0050780) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.1 3.0 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.1 0.8 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
0.1 1.7 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.1 3.0 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 0.8 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.1 0.7 GO:0016361 activin receptor activity, type I(GO:0016361)
0.1 0.4 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.1 1.3 GO:0045503 dynein light chain binding(GO:0045503)
0.1 3.3 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.1 1.3 GO:0043028 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.1 0.9 GO:0015250 water channel activity(GO:0015250)
0.1 0.8 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 0.8 GO:0016803 ether hydrolase activity(GO:0016803)
0.1 0.2 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.1 0.4 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.1 0.7 GO:0001217 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.1 0.5 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.1 2.6 GO:0008483 transaminase activity(GO:0008483)
0.1 4.6 GO:0043022 ribosome binding(GO:0043022)
0.1 0.4 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.1 0.5 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.1 1.1 GO:0042171 lysophosphatidic acid acyltransferase activity(GO:0042171)
0.1 0.4 GO:0004385 guanylate kinase activity(GO:0004385)
0.1 0.5 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 0.3 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.1 0.5 GO:0004966 galanin receptor activity(GO:0004966)
0.1 0.8 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.1 0.6 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1 0.6 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.1 0.4 GO:1990518 ATP-dependent 3'-5' DNA helicase activity(GO:0043140) single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity(GO:1990518)
0.1 0.6 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 1.0 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 4.5 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.1 0.2 GO:0004662 CAAX-protein geranylgeranyltransferase activity(GO:0004662)
0.1 2.1 GO:0030165 PDZ domain binding(GO:0030165)
0.1 1.9 GO:0016675 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 0.3 GO:0044548 S100 protein binding(GO:0044548)
0.1 0.2 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.1 1.2 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 0.4 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.1 0.6 GO:0004046 aminoacylase activity(GO:0004046)
0.1 1.0 GO:0033691 sialic acid binding(GO:0033691)
0.1 0.2 GO:0042834 peptidoglycan binding(GO:0042834) lipoteichoic acid binding(GO:0070891)
0.1 0.5 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.1 1.3 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 1.2 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.1 0.8 GO:0032051 clathrin light chain binding(GO:0032051)
0.1 0.6 GO:0005158 insulin receptor binding(GO:0005158)
0.1 0.2 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
0.1 0.2 GO:0098808 mRNA cap binding(GO:0098808)
0.1 0.5 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.1 0.7 GO:0051117 ATPase binding(GO:0051117)
0.1 0.7 GO:0055102 phospholipase inhibitor activity(GO:0004859) lipase inhibitor activity(GO:0055102)
0.1 0.6 GO:0015385 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.1 0.5 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.1 1.1 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.2 GO:0098973 structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.0 0.2 GO:0050254 rhodopsin kinase activity(GO:0050254)
0.0 1.4 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 0.6 GO:0015101 organic cation transmembrane transporter activity(GO:0015101)
0.0 0.2 GO:0015217 ATP:ADP antiporter activity(GO:0005471) ADP transmembrane transporter activity(GO:0015217)
0.0 1.3 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 2.2 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.2 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.1 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.0 0.2 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 2.0 GO:0003823 antigen binding(GO:0003823)
0.0 0.2 GO:0035620 ceramide transporter activity(GO:0035620) ceramide 1-phosphate binding(GO:1902387) ceramide 1-phosphate transporter activity(GO:1902388)
0.0 0.3 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.0 0.7 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.3 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 0.4 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.2 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.8 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.3 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 0.5 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 0.3 GO:0004100 chitin synthase activity(GO:0004100)
0.0 0.7 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.4 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.5 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.8 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.3 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.5 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.7 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.0 1.2 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.3 GO:0031628 opioid receptor binding(GO:0031628)
0.0 0.3 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.5 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.8 GO:0016860 intramolecular oxidoreductase activity(GO:0016860)
0.0 1.2 GO:0030145 manganese ion binding(GO:0030145)
0.0 0.3 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.5 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 0.5 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.3 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.4 GO:0031995 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
0.0 0.1 GO:0016672 oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672)
0.0 0.2 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 0.4 GO:0004180 carboxypeptidase activity(GO:0004180)
0.0 0.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.4 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.2 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.4 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.2 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 1.0 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.4 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.1 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.0 0.2 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 1.2 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.1 GO:1990715 mRNA CDS binding(GO:1990715)
0.0 1.2 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.4 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 0.3 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.0 0.8 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 1.7 GO:0003724 RNA helicase activity(GO:0003724)
0.0 0.1 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.4 GO:0031386 protein tag(GO:0031386)
0.0 0.3 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.5 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.1 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.2 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.0 0.3 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.2 GO:0004457 lactate dehydrogenase activity(GO:0004457)
0.0 0.4 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.3 GO:0030507 spectrin binding(GO:0030507)
0.0 0.1 GO:0015927 alpha,alpha-trehalase activity(GO:0004555) trehalase activity(GO:0015927)
0.0 0.1 GO:0008169 C-methyltransferase activity(GO:0008169)
0.0 1.1 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.2 GO:0016889 endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
0.0 3.0 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.7 GO:0019843 rRNA binding(GO:0019843)
0.0 0.5 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.6 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.5 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.1 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.0 0.1 GO:0019202 amino acid kinase activity(GO:0019202)
0.0 0.3 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.6 GO:0044325 ion channel binding(GO:0044325)
0.0 0.7 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.7 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 1.9 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 0.1 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.4 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.2 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.2 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 1.8 GO:0004866 endopeptidase inhibitor activity(GO:0004866)
0.0 1.1 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.3 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.3 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.6 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.8 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.4 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.2 GO:0042910 xenobiotic transporter activity(GO:0042910)
0.0 0.1 GO:0005223 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.3 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.1 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.9 GO:0016763 transferase activity, transferring pentosyl groups(GO:0016763)
0.0 0.1 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0 0.3 GO:0016289 CoA hydrolase activity(GO:0016289)
0.0 0.3 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 2.1 GO:0004252 serine-type endopeptidase activity(GO:0004252)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.5 PID ALK2 PATHWAY ALK2 signaling events
0.1 1.4 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 1.3 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 0.6 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1 1.6 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.1 0.6 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 0.5 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.4 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.5 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.9 PID CD40 PATHWAY CD40/CD40L signaling
0.0 1.3 PID MYC PATHWAY C-MYC pathway
0.0 1.7 PID ATR PATHWAY ATR signaling pathway
0.0 1.6 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.9 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.8 PID ARF6 PATHWAY Arf6 signaling events
0.0 2.0 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.2 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 0.4 PID CONE PATHWAY Visual signal transduction: Cones
0.0 2.9 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.4 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 0.2 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.2 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.2 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.1 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.1 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.2 2.5 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.2 7.7 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.2 2.5 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.2 0.6 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.2 1.2 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.2 3.5 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.2 1.1 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.1 1.7 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.1 1.4 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.1 1.2 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 5.1 REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS Genes involved in Activation of ATR in response to replication stress
0.1 0.2 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.1 0.9 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 0.4 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 1.0 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 0.5 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.1 0.8 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 1.0 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 1.0 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 0.6 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 0.5 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.1 1.3 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.1 0.5 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.4 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.3 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 2.2 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 0.2 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 1.3 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 1.8 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 2.4 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0 0.7 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.6 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0 0.8 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.3 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 3.1 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.3 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.7 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 0.6 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.2 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.5 REACTOME KINESINS Genes involved in Kinesins
0.0 0.5 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.3 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.3 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.2 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.1 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.2 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.1 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.9 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.3 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 0.1 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.3 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.3 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.6 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.2 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 0.1 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.2 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation
0.0 0.4 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4