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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for nfixa+nfixb

Z-value: 0.47

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Transcription factors associated with nfixa+nfixb

Gene Symbol Gene ID Gene Info
nfixa
ENSDARG00000043226 nuclear factor I/Xa
nfixb
ENSDARG00000061836 nuclear factor I/Xb

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nfixadr11_v1_chr1_+_51896147_518961470.136.2e-01Click!
nfixbdr11_v1_chr3_+_14768364_147683640.087.4e-01Click!

Activity profile of nfixa+nfixb motif

Sorted Z-values of nfixa+nfixb motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_5207152 1.96 ENSDART00000172751
si:ch73-223f5.2
si:ch73-223f5.2
chr25_-_16581233 1.80 ENSDART00000155312
smc1b
structural maintenance of chromosomes 1B
chr2_-_24488652 1.48 ENSDART00000052067
insl3
insulin-like 3 (Leydig cell)
chr8_-_52715911 1.41 ENSDART00000168241
tubb2b
tubulin, beta 2b
chr13_+_50375800 1.40 ENSDART00000099537
cox5b2
cytochrome c oxidase subunit Vb 2
chr2_-_14798295 1.23 ENSDART00000143430
ENSDART00000145869
si:ch73-366i20.1
si:ch73-366i20.1
chr4_-_8030583 1.21 ENSDART00000113628
si:ch211-240l19.8
si:ch211-240l19.8
chr7_-_25049377 1.15 ENSDART00000077191
arl2
ADP-ribosylation factor-like 2
chr14_+_6954579 1.09 ENSDART00000060998
nme5
NME/NM23 family member 5
chr2_-_24898226 1.07 ENSDART00000134936
si:dkey-149i17.9
si:dkey-149i17.9
chr17_-_39786222 0.99 ENSDART00000154515
pimr62
Pim proto-oncogene, serine/threonine kinase, related 62
chr4_+_17279966 0.98 ENSDART00000067005
ENSDART00000137487
bcat1
branched chain amino-acid transaminase 1, cytosolic
chr12_+_26471712 0.89 ENSDART00000162115
ndel1a
nudE neurodevelopment protein 1-like 1a
chr13_+_30804367 0.84 ENSDART00000053946
cxcl12a
chemokine (C-X-C motif) ligand 12a (stromal cell-derived factor 1)
chr5_-_51148298 0.80 ENSDART00000042420
ccdc180
coiled-coil domain containing 180
chr4_+_72235562 0.80 ENSDART00000168547
si:cabz01071912.2
si:cabz01071912.2
chr19_-_25464291 0.76 ENSDART00000112915
umad1
UBAP1-MVB12-associated (UMA) domain containing 1
chr6_-_49078263 0.69 ENSDART00000032982
slc5a8l
solute carrier family 5 (iodide transporter), member 8-like
chr5_+_20693724 0.68 ENSDART00000141368
si:ch211-240b21.2
si:ch211-240b21.2
chr8_+_46536893 0.68 ENSDART00000124023
pimr187
Pim proto-oncogene, serine/threonine kinase, related 187
chr17_+_14784275 0.67 ENSDART00000005355
rtraf
RNA transcription, translation and transport factor
chr22_+_18530395 0.67 ENSDART00000105415
ENSDART00000183958
si:ch211-212d10.1
si:ch211-212d10.1
chr16_+_7697878 0.67 ENSDART00000104176
ENSDART00000172977
ccr11.1
chemokine (C-C motif) receptor 11.1
chr6_-_9952103 0.65 ENSDART00000065475
zp2l2
zona pellucida glycoprotein 2, like 2
chr4_-_8040436 0.65 ENSDART00000113033
si:ch211-240l19.6
si:ch211-240l19.6
chr18_-_21177674 0.64 ENSDART00000060175
si:dkey-12e7.4
si:dkey-12e7.4
chr22_-_35330532 0.64 ENSDART00000172654
FO818743.1

chr15_+_36966369 0.63 ENSDART00000163622
kirrel3l
kirre like nephrin family adhesion molecule 3, like
chr17_+_33719415 0.62 ENSDART00000132294
fut8a
fucosyltransferase 8a (alpha (1,6) fucosyltransferase)
chr18_+_3037998 0.61 ENSDART00000185844
ENSDART00000162657
rps3
ribosomal protein S3
chr5_+_37087583 0.60 ENSDART00000049900
tagln2
transgelin 2
chr22_-_15602593 0.60 ENSDART00000036075
tpm4a
tropomyosin 4a
chr2_-_42375275 0.58 ENSDART00000026339
gtpbp4
GTP binding protein 4
chr8_+_27555314 0.57 ENSDART00000135568
ENSDART00000016696
rhocb
ras homolog family member Cb
chr13_+_15682803 0.57 ENSDART00000188063
CR931980.1

chr17_+_21817859 0.57 ENSDART00000143832
ENSDART00000141462
ikzf5
IKAROS family zinc finger 5
chr20_+_26880668 0.54 ENSDART00000077769
serpinb1
serpin peptidase inhibitor, clade B (ovalbumin), member 1
chr16_-_13595027 0.50 ENSDART00000060004
ntd5
ntl-dependent gene 5
chr11_-_17964525 0.50 ENSDART00000018948
cishb
cytokine inducible SH2-containing protein b
chr11_-_8262105 0.50 ENSDART00000173225
si:cabz01021066.1
si:cabz01021066.1
chr5_-_26181863 0.50 ENSDART00000098500
ccdc125
coiled-coil domain containing 125
chr22_+_34663328 0.49 ENSDART00000183912
si:ch73-304f21.1
si:ch73-304f21.1
chr3_-_2592350 0.49 ENSDART00000192325
si:dkey-217f16.5
si:dkey-217f16.5
chr14_+_39255437 0.49 ENSDART00000147443
diaph2
diaphanous-related formin 2
chr21_+_19858627 0.48 ENSDART00000147010
fybb
FYN binding protein b
chr2_-_41861040 0.47 ENSDART00000045763
keap1a
kelch-like ECH-associated protein 1a
chr19_-_7225060 0.46 ENSDART00000133179
ENSDART00000151138
ENSDART00000104799
ENSDART00000128331
col11a2
collagen, type XI, alpha 2
chr16_+_42482270 0.45 ENSDART00000184225
herpud2
HERPUD family member 2
chr15_-_39948635 0.45 ENSDART00000114836
msh5
mutS homolog 5
chr17_+_35431724 0.45 ENSDART00000190293
BX571665.1

chr11_-_22372072 0.45 ENSDART00000065996
tmem183a
transmembrane protein 183A
chr3_-_24980067 0.45 ENSDART00000048871
desi1a
desumoylating isopeptidase 1a
chr7_-_59054322 0.44 ENSDART00000165390
chmp5b
charged multivesicular body protein 5b
chr7_+_59649399 0.44 ENSDART00000123520
ENSDART00000040771
rpl34
ribosomal protein L34
chr22_-_15602760 0.43 ENSDART00000009054
tpm4a
tropomyosin 4a
chr1_-_22851481 0.43 ENSDART00000054386
qdprb1
quinoid dihydropteridine reductase b1
chr20_-_47188966 0.43 ENSDART00000152965
si:dkeyp-104f11.9
si:dkeyp-104f11.9
chr3_-_55139127 0.43 ENSDART00000115324
hbae1.3
hemoglobin, alpha embryonic 1.3
chr19_-_7144548 0.42 ENSDART00000147177
ENSDART00000134850
psmb8a
psmb13a
proteasome subunit beta 8A
proteasome subunit beta 13a
chr22_-_37611681 0.41 ENSDART00000028085
ttc14
tetratricopeptide repeat domain 14
chr3_-_8765165 0.40 ENSDART00000191131
CABZ01058333.1

chr25_-_30429607 0.39 ENSDART00000162429
ENSDART00000176535
si:ch211-93f2.1
si:ch211-93f2.1
chr18_-_48558420 0.39 ENSDART00000058987
kcnj1a.1
potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 1
chr5_-_30984271 0.39 ENSDART00000051392
spns3
spinster homolog 3 (Drosophila)
chr6_+_40661703 0.39 ENSDART00000142492
eno1b
enolase 1b, (alpha)
chr5_+_57641554 0.38 ENSDART00000171309
ENSDART00000157992
ENSDART00000164742
cryabb
crystallin, alpha B, b
chr5_-_10239079 0.38 ENSDART00000132739
si:ch73-42k18.1
si:ch73-42k18.1
chr6_+_32834760 0.38 ENSDART00000121562
cyldl
cylindromatosis (turban tumor syndrome), like
chr20_+_539852 0.38 ENSDART00000185994
dse
dermatan sulfate epimerase
chr16_+_23961276 0.37 ENSDART00000192754
apoeb
apolipoprotein Eb
chr14_+_11457500 0.37 ENSDART00000169202
si:ch211-153b23.5
si:ch211-153b23.5
chr2_+_38161318 0.37 ENSDART00000044264
mmp14b
matrix metallopeptidase 14b (membrane-inserted)
chr8_+_30671060 0.36 ENSDART00000193749
adora2aa
adenosine A2a receptor a
chr4_+_61171310 0.36 ENSDART00000141738
si:dkey-9p20.18
si:dkey-9p20.18
chr18_+_44649804 0.36 ENSDART00000059063
ehd2b
EH-domain containing 2b
chr24_-_20369760 0.34 ENSDART00000185585
dlec1
deleted in lung and esophageal cancer 1
chr21_-_36619599 0.34 ENSDART00000065208
nop16
NOP16 nucleolar protein homolog (yeast)
chr12_+_26632448 0.33 ENSDART00000185762
arhgap12b
Rho GTPase activating protein 12b
chr11_-_3865472 0.33 ENSDART00000161426
gata2a
GATA binding protein 2a
chr17_-_25563847 0.33 ENSDART00000040032
rtn4ip1
reticulon 4 interacting protein 1
chr16_+_23960933 0.32 ENSDART00000146077
apoeb
apolipoprotein Eb
chr24_+_26432541 0.32 ENSDART00000105784
ENSDART00000122554
cldn11b
claudin 11b
chr17_+_16873417 0.32 ENSDART00000146276
dio2
iodothyronine deiodinase 2
chr23_+_6544453 0.32 ENSDART00000005373
spo11
SPO11 meiotic protein covalently bound to DSB
chr2_-_45510223 0.31 ENSDART00000113058
gpsm2
G protein signaling modulator 2
chr22_-_11729350 0.31 ENSDART00000105813
krt222
keratin 222
chr14_+_18785727 0.31 ENSDART00000184452
si:ch211-111e20.1
si:ch211-111e20.1
chr23_-_3674443 0.30 ENSDART00000134830
ENSDART00000057422
pacsin1a
protein kinase C and casein kinase substrate in neurons 1a
chr3_-_39198113 0.30 ENSDART00000102690
RETSAT
zgc:154169
chr7_-_26457208 0.29 ENSDART00000173519
zgc:172079
zgc:172079
chr8_-_6877390 0.29 ENSDART00000170883
ENSDART00000005321
neflb
neurofilament, light polypeptide b
chr13_-_33683889 0.28 ENSDART00000136820
ENSDART00000065435
cst3
cystatin C (amyloid angiopathy and cerebral hemorrhage)
chr14_+_28438947 0.28 ENSDART00000006489
acsl4a
acyl-CoA synthetase long chain family member 4a
chr25_-_18002937 0.28 ENSDART00000149696
cep290
centrosomal protein 290
chr4_-_38033800 0.27 ENSDART00000159662
si:dkeyp-82b4.4
si:dkeyp-82b4.4
chr7_+_25049545 0.26 ENSDART00000173896
ENSDART00000173566
si:dkey-23i12.7
ppp2r5b
si:dkey-23i12.7
protein phosphatase 2, regulatory subunit B', beta
chr10_+_5025696 0.26 ENSDART00000031165
enoph1
enolase-phosphatase 1
chr18_-_17529763 0.26 ENSDART00000191308
bbs2
Bardet-Biedl syndrome 2
chr9_-_2572790 0.25 ENSDART00000135076
ENSDART00000016710
scrn3
secernin 3
chr8_-_20138054 0.25 ENSDART00000133141
ENSDART00000147634
ENSDART00000029939
rfx2
regulatory factor X, 2 (influences HLA class II expression)
chr21_+_27448856 0.25 ENSDART00000100784
cfbl
complement factor b-like
chr17_-_8886735 0.25 ENSDART00000121997
nkl.3
NK-lysin tandem duplicate 3
chr4_-_12388535 0.25 ENSDART00000017180
rergla
RERG/RAS-like a
chr24_-_38574631 0.24 ENSDART00000154539
slc17a7b
solute carrier family 17 (vesicular glutamate transporter), member 7b
chr9_+_13999620 0.24 ENSDART00000143229
cd28l
cd28-like molecule
chr15_-_28082310 0.24 ENSDART00000152620
dhrs13a.3
dehydrogenase/reductase (SDR family) member 13a, duplicate 3
chr14_+_11458044 0.23 ENSDART00000186425
si:ch211-153b23.5
si:ch211-153b23.5
chr7_+_35238234 0.23 ENSDART00000178732
tppp3
tubulin polymerization-promoting protein family member 3
chr21_-_25555355 0.23 ENSDART00000144228
si:dkey-17e16.9
si:dkey-17e16.9
chr8_+_48858132 0.22 ENSDART00000124737
ENSDART00000079644
tp73
tumor protein p73
chr25_-_30394746 0.22 ENSDART00000185346
si:ch211-93f2.1
si:ch211-93f2.1
chr14_-_21064199 0.22 ENSDART00000172099
si:dkey-74k8.3
si:dkey-74k8.3
chr1_+_22851261 0.22 ENSDART00000193925
gtf2e2
general transcription factor IIE, polypeptide 2, beta
chr7_+_57108823 0.22 ENSDART00000184943
ENSDART00000055956
enosf1
enolase superfamily member 1
chr18_-_48983690 0.22 ENSDART00000182359
FO681288.3

chr9_-_22963897 0.21 ENSDART00000133676
si:dkey-91i10.2
si:dkey-91i10.2
chr25_+_27923846 0.21 ENSDART00000047007
slc13a1
solute carrier family 13 member 1
chr22_+_19553390 0.21 ENSDART00000061739
hsd11b1la
hydroxysteroid (11-beta) dehydrogenase 1-like a
chr14_+_25465346 0.21 ENSDART00000173436
si:dkey-280e21.3
si:dkey-280e21.3
chr4_+_70556298 0.21 ENSDART00000170985
si:dkey-11d20.1
si:dkey-11d20.1
chr20_+_32497260 0.21 ENSDART00000145175
ENSDART00000132921
si:ch73-257c13.2
si:ch73-257c13.2
chr20_+_38525567 0.21 ENSDART00000147787
znf512
zinc finger protein 512
chr19_-_24163845 0.20 ENSDART00000133277
prf1.2
perforin 1.2
chr12_-_6880694 0.20 ENSDART00000171846
pcdh15b
protocadherin-related 15b
chr3_-_26921475 0.20 ENSDART00000130281
ciita
class II, major histocompatibility complex, transactivator
chr13_-_20381485 0.20 ENSDART00000131351
si:ch211-270n8.1
si:ch211-270n8.1
chr9_+_51147764 0.20 ENSDART00000188480
ifih1
interferon induced with helicase C domain 1
chr16_-_28876479 0.19 ENSDART00000047862
si:dkey-239n17.4
si:dkey-239n17.4
chr18_+_17660158 0.19 ENSDART00000186279
cpne2
copine II
chr19_+_30387999 0.19 ENSDART00000145396
tspan13b
tetraspanin 13b
chr10_+_39263827 0.19 ENSDART00000172509
foxred1
FAD-dependent oxidoreductase domain containing 1
chr11_-_1933793 0.19 ENSDART00000186850
faim2b
Fas apoptotic inhibitory molecule 2b
chr6_-_35052145 0.19 ENSDART00000073970
ENSDART00000185790
uap1
UDP-N-acetylglucosamine pyrophosphorylase 1
chr1_-_51684941 0.19 ENSDART00000113853
prokr1a
prokineticin receptor 1a
chr6_-_24301324 0.18 ENSDART00000171401
BX927081.1

chr19_-_12404590 0.18 ENSDART00000103703
ftr56
finTRIM family, member 56
chr15_-_18361475 0.18 ENSDART00000155866
zbtb16b
zinc finger and BTB domain containing 16b
chr16_-_22713152 0.17 ENSDART00000140953
ENSDART00000143836
si:ch211-105c13.3
si:ch211-105c13.3
chr16_+_46430627 0.17 ENSDART00000127681
rpz6
rapunzel 6
chr9_+_54237100 0.17 ENSDART00000148928
rbm27
RNA binding motif protein 27
chr1_-_46862190 0.17 ENSDART00000145167
agpat3
1-acylglycerol-3-phosphate O-acyltransferase 3
chr13_+_17672527 0.17 ENSDART00000148269
ENSDART00000137776
comtd1
catechol-O-methyltransferase domain containing 1
chr22_+_5478353 0.17 ENSDART00000160596
tppp
tubulin polymerization promoting protein
chr21_-_4032650 0.17 ENSDART00000151648
ntng2b
netrin g2b
chr21_-_2958422 0.16 ENSDART00000174091
zgc:194215
zgc:194215
chr6_-_8580857 0.16 ENSDART00000138858
ENSDART00000041142
myh11a
myosin, heavy chain 11a, smooth muscle
chr17_-_48743076 0.15 ENSDART00000173117
kcnk17
potassium channel, subfamily K, member 17
chr24_-_28381404 0.15 ENSDART00000148406
prkag2a
protein kinase, AMP-activated, gamma 2 non-catalytic subunit a
chr19_-_29832876 0.14 ENSDART00000005119
eif3i
eukaryotic translation initiation factor 3, subunit I
chr2_-_14793343 0.14 ENSDART00000132264
si:ch73-366i20.1
si:ch73-366i20.1
chr3_+_54744069 0.14 ENSDART00000134958
ENSDART00000114443
si:ch211-74m13.3
si:ch211-74m13.3
chr1_-_54706039 0.14 ENSDART00000083633
exosc1
exosome component 1
chr17_-_14451405 0.14 ENSDART00000146786
jkamp
jnk1/mapk8 associated membrane protein
chr16_-_49846359 0.14 ENSDART00000184246
znf385d
zinc finger protein 385D
chr2_-_58193381 0.14 ENSDART00000159040
pnp5b
purine nucleoside phosphorylase 5b
chr19_+_30990815 0.14 ENSDART00000134645
sync
syncoilin, intermediate filament protein
chr5_-_57641257 0.13 ENSDART00000149282
hspb2
heat shock protein, alpha-crystallin-related, b2
chr23_+_13721826 0.13 ENSDART00000142494
zbtb46
zinc finger and BTB domain containing 46
chr1_-_58900851 0.13 ENSDART00000183085
ENSDART00000188855
ENSDART00000182567
CABZ01084501.3
Danio rerio microfibril-associated glycoprotein 4-like (LOC100334800), transcript variant 2, mRNA.
chr11_+_44579865 0.13 ENSDART00000173425
nid1b
nidogen 1b
chr22_+_5176255 0.13 ENSDART00000092647
cers1
ceramide synthase 1
chr8_+_52642869 0.12 ENSDART00000163617
ENSDART00000189997
si:dkey-90l8.3
si:dkey-90l8.3
chr9_+_6587364 0.12 ENSDART00000122279
fhl2a
four and a half LIM domains 2a
chr16_-_29458806 0.12 ENSDART00000047931
lingo4b
leucine rich repeat and Ig domain containing 4b
chr9_-_39968820 0.12 ENSDART00000100311
IKZF2
si:zfos-1425h8.1
chr3_-_32603191 0.12 ENSDART00000150997
si:ch73-248e21.7
si:ch73-248e21.7
chr5_+_45918680 0.12 ENSDART00000036242
ankdd1b
ankyrin repeat and death domain containing 1B
chr18_+_17660402 0.12 ENSDART00000143475
cpne2
copine II
chr15_-_40246396 0.11 ENSDART00000063777
kcnj13
potassium inwardly-rectifying channel, subfamily J, member 13
chr22_-_28653074 0.11 ENSDART00000154717
col8a1b
collagen, type VIII, alpha 1b
chr7_-_21928826 0.11 ENSDART00000088043
si:dkey-85k7.11
si:dkey-85k7.11
chr6_+_39905021 0.11 ENSDART00000064904
endou
endonuclease, polyU-specific
chr8_+_28469054 0.11 ENSDART00000062716
slc52a3
solute carrier family 52 (riboflavin transporter), member 3
chr1_-_9644630 0.11 ENSDART00000123725
ENSDART00000161164
ugt5b3
UDP glucuronosyltransferase 5 family, polypeptide B3
chr8_+_31016180 0.11 ENSDART00000130870
ENSDART00000143604
odf2b
outer dense fiber of sperm tails 2b
chr12_-_37941733 0.11 ENSDART00000130167
CABZ01046949.1

chr22_+_18816662 0.11 ENSDART00000132476
cbarpb
calcium channel, voltage-dependent, beta subunit associated regulatory protein b
chr22_-_13544244 0.10 ENSDART00000110136
cntnap5b
contactin associated protein-like 5b
chr22_+_12477996 0.10 ENSDART00000177704
CR847870.3

chr23_+_44741500 0.10 ENSDART00000166421
atp1b2a
ATPase Na+/K+ transporting subunit beta 2a
chr11_-_13151841 0.10 ENSDART00000161983
elovl1b
ELOVL fatty acid elongase 1b
chr25_-_19068557 0.10 ENSDART00000184780
cacna2d4b
calcium channel, voltage-dependent, alpha 2/delta subunit 4b
chr2_-_37889111 0.10 ENSDART00000168939
ENSDART00000098529
mbl2
mannose binding lectin 2
chr19_+_10603405 0.10 ENSDART00000151135
si:dkey-211g8.8
si:dkey-211g8.8
chr22_+_5176693 0.10 ENSDART00000160927
cers1
ceramide synthase 1
chr19_-_24443867 0.10 ENSDART00000163763
ENSDART00000043133
thbs3b
thrombospondin 3b
chr6_-_21873266 0.10 ENSDART00000151658
ENSDART00000151152
ENSDART00000151179
si:dkey-19e4.5
si:dkey-19e4.5
chr20_-_29229843 0.10 ENSDART00000101418
ENSDART00000184637
chrm5b
cholinergic receptor, muscarinic 5b
chr10_-_26738209 0.10 ENSDART00000188590
fgf13b
fibroblast growth factor 13b
chr19_+_4463389 0.09 ENSDART00000168805
kcnk9
potassium channel, subfamily K, member 9
chr16_+_48682309 0.09 ENSDART00000183957
tap1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr13_+_18545819 0.09 ENSDART00000101859
ENSDART00000110197
ENSDART00000136064
zgc:154058
zgc:154058
chr19_+_10831362 0.09 ENSDART00000053325
tomm40l
translocase of outer mitochondrial membrane 40 homolog, like
chr4_+_29206813 0.09 ENSDART00000131893
si:dkey-23a23.1
si:dkey-23a23.1
chr10_-_36231741 0.09 ENSDART00000170641
or109-4
odorant receptor, family D, subfamily 109, member 4
chr15_-_29387446 0.09 ENSDART00000145976
ENSDART00000035096
serpinh1b
serpin peptidase inhibitor, clade H (heat shock protein 47), member 1b
chr21_-_18993110 0.09 ENSDART00000144086
si:ch211-222n4.6
si:ch211-222n4.6
chr3_+_52467879 0.09 ENSDART00000156039
adgre5a
adhesion G protein-coupled receptor E5a
chr22_+_11857356 0.09 ENSDART00000179540
mras
muscle RAS oncogene homolog
chr21_+_15866522 0.08 ENSDART00000110728
gcnt4b
glucosaminyl (N-acetyl) transferase 4, core 2, b

Network of associatons between targets according to the STRING database.

First level regulatory network of nfixa+nfixb

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:1902175 regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902175) negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902176)
0.3 0.8 GO:2000471 regulation of hematopoietic stem cell migration(GO:2000471)
0.2 1.0 GO:0009098 leucine biosynthetic process(GO:0009098)
0.2 0.7 GO:0034382 chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830) intermediate-density lipoprotein particle clearance(GO:0071831)
0.2 1.1 GO:0031116 positive regulation of microtubule polymerization(GO:0031116)
0.1 0.9 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.1 0.3 GO:1902895 pri-miRNA transcription from RNA polymerase II promoter(GO:0061614) regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902893) positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895)
0.1 1.4 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 0.6 GO:0071908 determination of intestine left/right asymmetry(GO:0071908)
0.1 0.4 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.1 0.3 GO:0019284 L-methionine biosynthetic process from S-adenosylmethionine(GO:0019284)
0.1 0.6 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.1 0.4 GO:0030205 dermatan sulfate metabolic process(GO:0030205)
0.1 0.7 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.4 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.0 0.5 GO:0071379 cellular response to prostaglandin stimulus(GO:0071379)
0.0 0.3 GO:1900744 regulation of p38MAPK cascade(GO:1900744)
0.0 0.3 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.0 0.3 GO:0042403 thyroid hormone metabolic process(GO:0042403)
0.0 0.3 GO:0000706 meiotic DNA double-strand break processing(GO:0000706)
0.0 0.2 GO:0010332 response to gamma radiation(GO:0010332) cellular response to gamma radiation(GO:0071480)
0.0 0.4 GO:0051877 pigment granule aggregation in cell center(GO:0051877)
0.0 0.5 GO:0000710 meiotic mismatch repair(GO:0000710)
0.0 0.4 GO:0001958 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 0.6 GO:0036065 fucosylation(GO:0036065)
0.0 0.5 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 1.0 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 0.2 GO:0032608 interferon-beta production(GO:0032608) regulation of interferon-beta production(GO:0032648) positive regulation of interferon-beta production(GO:0032728)
0.0 0.6 GO:2001235 positive regulation of apoptotic signaling pathway(GO:2001235)
0.0 0.2 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.0 0.6 GO:0007520 myoblast fusion(GO:0007520) pronephric duct development(GO:0039022)
0.0 0.2 GO:0032481 positive regulation of type I interferon production(GO:0032481)
0.0 0.1 GO:0019884 antigen processing and presentation of exogenous peptide antigen(GO:0002478) antigen processing and presentation of exogenous antigen(GO:0019884) antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.0 0.6 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.2 GO:0030859 polarized epithelial cell differentiation(GO:0030859)
0.0 0.4 GO:0015671 oxygen transport(GO:0015671)
0.0 0.4 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.0 1.4 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.0 0.1 GO:0032218 riboflavin transport(GO:0032218)
0.0 2.8 GO:0070646 protein modification by small protein removal(GO:0070646)
0.0 0.2 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.0 GO:0007509 mesoderm migration involved in gastrulation(GO:0007509)
0.0 0.6 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.1 GO:0099612 protein localization to juxtaparanode region of axon(GO:0071205) protein localization to axon(GO:0099612)
0.0 0.1 GO:1903170 negative regulation of calcium ion-dependent exocytosis(GO:0045955) negative regulation of calcium ion transmembrane transporter activity(GO:1901020) negative regulation of voltage-gated calcium channel activity(GO:1901386) negative regulation of calcium ion transmembrane transport(GO:1903170) negative regulation of regulated secretory pathway(GO:1903306)
0.0 0.2 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.7 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.0 0.3 GO:0097320 membrane tubulation(GO:0097320)
0.0 0.2 GO:0042574 retinal metabolic process(GO:0042574)
0.0 0.4 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.5 GO:0040001 establishment of mitotic spindle localization(GO:0040001)
0.0 0.3 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.0 0.2 GO:0046785 microtubule polymerization(GO:0046785)
0.0 0.1 GO:0035176 social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.0 0.1 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 0.5 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 0.1 GO:0070836 membrane raft assembly(GO:0001765) plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) caveola assembly(GO:0070836)
0.0 0.0 GO:0010882 regulation of cardiac muscle contraction by calcium ion signaling(GO:0010882)
0.0 0.1 GO:0019372 lipoxygenase pathway(GO:0019372) linoleic acid metabolic process(GO:0043651) hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.1 1.1 GO:0030893 meiotic cohesin complex(GO:0030893)
0.1 0.5 GO:0016234 inclusion body(GO:0016234)
0.1 0.3 GO:0005883 neurofilament(GO:0005883)
0.0 0.4 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.2 GO:0005673 transcription factor TFIIE complex(GO:0005673)
0.0 0.3 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.1 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.4 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.3 GO:0034464 BBSome(GO:0034464)
0.0 0.3 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.4 GO:0005771 multivesicular body(GO:0005771)
0.0 0.1 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.0 0.4 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.2 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.2 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.1 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.6 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.1 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.6 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.1 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0004084 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.2 0.7 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.2 0.8 GO:0015355 secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.1 0.4 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.1 1.4 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 0.4 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.1 0.3 GO:0070004 cysteine-type exopeptidase activity(GO:0070004)
0.0 0.1 GO:0005252 open rectifier potassium channel activity(GO:0005252)
0.0 0.4 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.8 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.2 GO:0003977 UDP-N-acetylglucosamine diphosphorylase activity(GO:0003977)
0.0 0.6 GO:0008417 fucosyltransferase activity(GO:0008417)
0.0 0.4 GO:0031720 haptoglobin binding(GO:0031720)
0.0 0.3 GO:0016889 endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
0.0 0.7 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.4 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.3 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.0 0.5 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 0.1 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 1.4 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.2 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.4 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.4 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.1 GO:0032217 riboflavin transporter activity(GO:0032217)
0.0 0.1 GO:0046977 peptide antigen-transporting ATPase activity(GO:0015433) peptide-transporting ATPase activity(GO:0015440) TAP binding(GO:0046977)
0.0 0.1 GO:0033765 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) enone reductase activity(GO:0035671) cholestenone 5-alpha-reductase activity(GO:0047751)
0.0 2.0 GO:0101005 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.7 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.2 GO:0005326 neurotransmitter transporter activity(GO:0005326)
0.0 0.1 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 0.4 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.1 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.0 0.5 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.2 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.0 GO:0008397 sterol 12-alpha-hydroxylase activity(GO:0008397)
0.0 0.3 GO:0019211 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.0 0.1 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.2 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 0.1 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.2 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 1.5 GO:0005179 hormone activity(GO:0005179)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.1 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.4 NABA COLLAGENS Genes encoding collagen proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 1.8 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.1 1.0 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.2 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.3 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.3 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 1.5 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.3 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.3 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.8 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.2 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.2 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.1 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.1 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis