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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for nkx2.2b

Z-value: 0.94

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Transcription factors associated with nkx2.2b

Gene Symbol Gene ID Gene Info
nkx2.2b
ENSDARG00000101549 NK2 homeobox 2b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nkx2.2bdr11_v1_chr20_+_48782068_48782068-0.503.4e-02Click!

Activity profile of nkx2.2b motif

Sorted Z-values of nkx2.2b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr13_+_47710434 1.95 ENSDART00000188724
TMEM87B
transmembrane protein 87B
chr4_-_837768 1.93 ENSDART00000185280
ENSDART00000135618
sobpb
sine oculis binding protein homolog (Drosophila) b
chr4_-_20081621 1.74 ENSDART00000024647
dennd6b
DENN/MADD domain containing 6B
chr22_-_17631675 1.73 ENSDART00000132565
hmha1b
histocompatibility (minor) HA-1 b
chr24_-_33308045 1.72 ENSDART00000149711
slc4a2b
solute carrier family 4 (anion exchanger), member 2b
chr10_+_41945890 1.67 ENSDART00000063013
ENSDART00000128313
tmem120b
transmembrane protein 120B
chr11_+_42422371 1.67 ENSDART00000163780
dennd6aa
DENN/MADD domain containing 6Aa
chr17_+_12075805 1.60 ENSDART00000155329
cnsta
consortin, connexin sorting protein a
chr6_-_49547680 1.54 ENSDART00000169678
ppp4r1l
protein phosphatase 4, regulatory subunit 1-like
chr7_-_71585065 1.49 ENSDART00000128678
mettl4
methyltransferase like 4
chr6_-_19341184 1.46 ENSDART00000168236
ENSDART00000167674
mif4gda
MIF4G domain containing a
chr12_+_33320884 1.43 ENSDART00000188988
csnk1db
casein kinase 1, delta b
chr6_+_10338554 1.43 ENSDART00000186936
cobll1a
cordon-bleu WH2 repeat protein-like 1a
chr8_+_52442622 1.42 ENSDART00000012758
zgc:77112
zgc:77112
chr13_-_33317323 1.41 ENSDART00000110295
ENSDART00000144848
ENSDART00000136701
tmem234
transmembrane protein 234
chr13_+_8840772 1.41 ENSDART00000059321
epcam
epithelial cell adhesion molecule
chr10_-_32877348 1.37 ENSDART00000018977
ENSDART00000133421
rabgef1
RAB guanine nucleotide exchange factor (GEF) 1
chr18_-_35407695 1.34 ENSDART00000191845
ENSDART00000141703
snrpa
small nuclear ribonucleoprotein polypeptide A
chr23_+_36730713 1.32 ENSDART00000113179
tspan31
tetraspanin 31
chr11_-_25257595 1.32 ENSDART00000123567
snai1a
snail family zinc finger 1a
chr16_-_8132742 1.29 ENSDART00000104323
snrka
SNF related kinase a
chr4_-_20108833 1.29 ENSDART00000100867
fam3c
family with sequence similarity 3, member C
chr14_+_26759332 1.28 ENSDART00000088484
ahnak
AHNAK nucleoprotein
chr2_-_42552666 1.28 ENSDART00000141399
dip2cb
disco-interacting protein 2 homolog Cb
chr24_-_32522587 1.27 ENSDART00000048968
ENSDART00000143781
EIF1B
zgc:56676
chr2_-_10877228 1.27 ENSDART00000138718
ENSDART00000034246
cdc7
cell division cycle 7 homolog (S. cerevisiae)
chr11_+_37638873 1.26 ENSDART00000186384
ENSDART00000184291
ENSDART00000131782
ENSDART00000140502
sh2d5
SH2 domain containing 5
chr12_-_4301234 1.26 ENSDART00000152377
ENSDART00000152521
ca15b
carbonic anhydrase XVb
chr16_-_4610255 1.25 ENSDART00000081852
ENSDART00000123253
ENSDART00000127554
ENSDART00000029485
arnt
aryl hydrocarbon receptor nuclear translocator
chr13_+_33368140 1.25 ENSDART00000033848
brf1a
BRF1, RNA polymerase III transcription initiation factor a
chr16_+_40340523 1.24 ENSDART00000102571
mettl6
methyltransferase like 6
chr1_-_40341306 1.23 ENSDART00000190649
maml3
mastermind-like transcriptional coactivator 3
chr20_-_32045057 1.21 ENSDART00000152970
ENSDART00000034248
rab32a
RAB32a, member RAS oncogene family
chr6_-_49537646 1.21 ENSDART00000180438
FO704848.1

chr16_-_22585289 1.20 ENSDART00000134239
ENSDART00000193959
ENSDART00000077998
si:dkey-238m4.3
cgna
si:dkey-238m4.3
cingulin a
chr8_-_1698155 1.19 ENSDART00000186159
CABZ01065417.1

chr1_-_43905252 1.19 ENSDART00000135477
ENSDART00000132089
si:dkey-22i16.3
si:dkey-22i16.3
chr7_-_26518086 1.18 ENSDART00000058913
eif4a1a
eukaryotic translation initiation factor 4A1A
chr22_+_883678 1.15 ENSDART00000140588
stk38b
serine/threonine kinase 38b
chr24_-_26518972 1.15 ENSDART00000097792
tnikb
TRAF2 and NCK interacting kinase b
chr6_-_8465656 1.13 ENSDART00000178887
si:dkey-217d24.6
si:dkey-217d24.6
chr20_+_25712276 1.12 ENSDART00000121585
ENSDART00000185772
cep135
centrosomal protein 135
chr14_+_30398546 1.11 ENSDART00000053925
mtmr7a
myotubularin related protein 7a
chr6_+_21227621 1.10 ENSDART00000193583
prkca
protein kinase C, alpha
chr25_-_998096 1.09 ENSDART00000164082
znf609a
zinc finger protein 609a
chr11_+_42422638 1.08 ENSDART00000042599
ENSDART00000181175
dennd6aa
DENN/MADD domain containing 6Aa
chr1_-_55248496 1.08 ENSDART00000098615
nanos3
nanos homolog 3
chr1_+_30723380 1.07 ENSDART00000127943
ENSDART00000062628
ENSDART00000127670
bora
bora, aurora kinase A activator
chr12_-_25150239 1.07 ENSDART00000038415
ENSDART00000135368
rhoq
ras homolog family member Q
chr1_-_354115 1.07 ENSDART00000141590
ENSDART00000098627
pros1
protein S
chr8_+_3431671 1.06 ENSDART00000017850
ctu1
cytosolic thiouridylase subunit 1 homolog (S. pombe)
chr9_-_14273652 1.04 ENSDART00000135458
abcb6b
ATP-binding cassette, sub-family B (MDR/TAP), member 6b
chr10_+_20392083 1.03 ENSDART00000166867
r3hcc1
R3H domain and coiled-coil containing 1
chr4_-_12477224 1.03 ENSDART00000027756
ENSDART00000182706
ENSDART00000127150
arhgef39
Rho guanine nucleotide exchange factor (GEF) 39
chr14_+_22132896 0.99 ENSDART00000138274
ccng1
cyclin G1
chr2_-_21786826 0.98 ENSDART00000016208
chd7
chromodomain helicase DNA binding protein 7
chr15_-_37589600 0.98 ENSDART00000154641
proser3
proline and serine rich 3
chr24_+_41989108 0.97 ENSDART00000169725
zbtb14
zinc finger and BTB domain containing 14
chr4_-_5108844 0.95 ENSDART00000132666
ENSDART00000136096
tmem209
transmembrane protein 209
chr7_-_64770456 0.95 ENSDART00000192618
zdhhc21
zinc finger, DHHC-type containing 21
chr20_+_53368611 0.94 ENSDART00000060432
cdc40
cell division cycle 40 homolog (S. cerevisiae)
chr5_-_57204352 0.94 ENSDART00000171252
ENSDART00000180727
man2a1
mannosidase, alpha, class 2A, member 1
chr20_-_2298970 0.93 ENSDART00000136067
EPB41L2
si:ch73-18b11.1
chr11_+_18873619 0.93 ENSDART00000176141
magi1b
membrane associated guanylate kinase, WW and PDZ domain containing 1b
chr2_-_10943093 0.93 ENSDART00000148999
ssbp3a
single stranded DNA binding protein 3a
chr18_+_26428829 0.92 ENSDART00000190779
ENSDART00000193226
ENSDART00000110746
blm
Bloom syndrome, RecQ helicase-like
chr19_-_5058908 0.92 ENSDART00000130062
chd4a
chromodomain helicase DNA binding protein 4a
chr6_+_1724889 0.92 ENSDART00000157415
acvr2ab
activin A receptor type 2Ab
chr13_+_33368503 0.91 ENSDART00000139650
brf1a
BRF1, RNA polymerase III transcription initiation factor a
chr12_-_1031970 0.91 ENSDART00000105292
polr3e
polymerase (RNA) III (DNA directed) polypeptide E
chr5_+_16117871 0.91 ENSDART00000090657
znrf3
zinc and ring finger 3
chr14_+_22132388 0.91 ENSDART00000109065
ccng1
cyclin G1
chr3_+_39579393 0.91 ENSDART00000055170
cln3
ceroid-lipofuscinosis, neuronal 3
chr13_+_36595618 0.91 ENSDART00000022684
cnih1
cornichon family AMPA receptor auxiliary protein 1
chr18_-_27316599 0.90 ENSDART00000028294
zgc:56106
zgc:56106
chr22_+_28818291 0.90 ENSDART00000136032
tp53bp2b
tumor protein p53 binding protein, 2b
chr1_-_47122058 0.90 ENSDART00000159925
ENSDART00000101143
ENSDART00000176803
mhc1zea
major histocompatibility complex class I ZEA
chr12_-_22400999 0.90 ENSDART00000153194
si:dkey-38p12.3
si:dkey-38p12.3
chr22_-_21676364 0.89 ENSDART00000183668
tle2b
transducin like enhancer of split 2b
chr14_-_26392475 0.88 ENSDART00000170614
b4galt7
xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7 (galactosyltransferase I)
chr22_-_20924564 0.87 ENSDART00000100642
ENSDART00000032770
ell
elongation factor RNA polymerase II
chr20_+_46620374 0.87 ENSDART00000005548
batf
basic leucine zipper transcription factor, ATF-like
chr17_+_19481049 0.86 ENSDART00000024194
kif11
kinesin family member 11
chr13_+_15581270 0.86 ENSDART00000189880
ENSDART00000190067
ENSDART00000041293
mark3a
MAP/microtubule affinity-regulating kinase 3a
chr4_+_16784553 0.85 ENSDART00000134054
si:dkey-13i19.8
si:dkey-13i19.8
chr16_-_31284922 0.85 ENSDART00000142638
mroh1
maestro heat-like repeat family member 1
chr16_+_20056030 0.85 ENSDART00000027020
ankrd28b
ankyrin repeat domain 28b
chr3_+_18807524 0.84 ENSDART00000055757
tnpo2
transportin 2 (importin 3, karyopherin beta 2b)
chr12_-_3705862 0.83 ENSDART00000193864
ENSDART00000185857
CABZ01069040.1

chr2_-_32387441 0.82 ENSDART00000148202
ubtfl
upstream binding transcription factor, like
chr3_-_26806032 0.82 ENSDART00000143710
pigq
phosphatidylinositol glycan anchor biosynthesis, class Q
chr22_+_35131890 0.82 ENSDART00000003303
ENSDART00000130581
rnf13
ring finger protein 13
chr3_-_34136778 0.81 ENSDART00000131951
clpp
caseinolytic mitochondrial matrix peptidase proteolytic subunit
chr4_+_5334202 0.79 ENSDART00000150409
apex1
APEX nuclease (multifunctional DNA repair enzyme) 1
chr23_+_4226341 0.78 ENSDART00000012445
zgc:113278
zgc:113278
chr5_-_33886495 0.78 ENSDART00000159058
dab2ipb
DAB2 interacting protein b
chr17_-_29312506 0.78 ENSDART00000133668
tecpr2
tectonin beta-propeller repeat containing 2
chr4_+_5196469 0.77 ENSDART00000067386
rad51ap1
RAD51 associated protein 1
chr22_+_835728 0.77 ENSDART00000003325
dennd2db
DENN/MADD domain containing 2Db
chr24_+_24726956 0.77 ENSDART00000144574
ENSDART00000066628
mtfr1
mitochondrial fission regulator 1
chr13_-_32726178 0.76 ENSDART00000012232
pdss2
prenyl (decaprenyl) diphosphate synthase, subunit 2
chr24_+_10039165 0.76 ENSDART00000144186
pou6f2
POU class 6 homeobox 2
chr20_-_53963515 0.76 ENSDART00000110252
ppp2r5cb
protein phosphatase 2, regulatory subunit B', gamma b
chr21_+_43178831 0.75 ENSDART00000151512
aff4
AF4/FMR2 family, member 4
chr19_+_24039830 0.75 ENSDART00000100422
rit1
Ras-like without CAAX 1
chr5_+_3927989 0.75 ENSDART00000030125
znhit3
zinc finger, HIT-type containing 3
chr14_+_45608576 0.75 ENSDART00000173248
si:ch211-276i12.11
si:ch211-276i12.11
chr10_-_7702029 0.74 ENSDART00000018017
gmcl1
germ cell-less, spermatogenesis associated 1
chr17_+_6538733 0.73 ENSDART00000193712
slc5a6b
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
chr21_+_19547806 0.73 ENSDART00000159707
ENSDART00000184869
ENSDART00000181321
ENSDART00000058487
ENSDART00000058485
rai14
retinoic acid induced 14
chr19_-_5058515 0.71 ENSDART00000150980
chd4a
chromodomain helicase DNA binding protein 4a
chr24_-_31332087 0.71 ENSDART00000161179
abcd3a
ATP-binding cassette, sub-family D (ALD), member 3a
chr16_+_39242339 0.71 ENSDART00000102510
zgc:77056
zgc:77056
chr8_-_49728590 0.71 ENSDART00000135714
ENSDART00000138810
ENSDART00000098319
gkap1
G kinase anchoring protein 1
chr19_+_30867845 0.70 ENSDART00000047461
mfsd2ab
major facilitator superfamily domain containing 2ab
chr15_+_24746444 0.70 ENSDART00000032306
ywhae1
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 1
chr3_-_26805455 0.70 ENSDART00000180648
pigq
phosphatidylinositol glycan anchor biosynthesis, class Q
chr12_+_19138452 0.69 ENSDART00000141346
ENSDART00000066397
phf5a
PHD finger protein 5A
chr20_+_2739531 0.69 ENSDART00000152269
syncrip
synaptotagmin binding, cytoplasmic RNA interacting protein
chr12_+_33361948 0.68 ENSDART00000124982
fasn
fatty acid synthase
chr17_+_22577472 0.68 ENSDART00000045099
yipf4
Yip1 domain family, member 4
chr2_-_22530969 0.67 ENSDART00000159641
znf644a
zinc finger protein 644a
chr20_-_28698172 0.67 ENSDART00000190635
sipa1l1
signal-induced proliferation-associated 1 like 1
chr11_-_11961706 0.67 ENSDART00000115249
abcc10
ATP-binding cassette, sub-family C (CFTR/MRP), member 10
chr2_-_58183499 0.67 ENSDART00000172281
ENSDART00000186262
si:ch1073-185p12.2
si:ch1073-185p12.2
chr4_+_5333988 0.67 ENSDART00000129398
ENSDART00000163850
ENSDART00000067374
ENSDART00000150780
ENSDART00000150493
ENSDART00000150306
apex1
APEX nuclease (multifunctional DNA repair enzyme) 1
chr16_-_25400257 0.66 ENSDART00000040756
zgc:136493
zgc:136493
chr22_+_11775269 0.66 ENSDART00000140272
krt96
keratin 96
chr2_+_2967255 0.65 ENSDART00000167649
ENSDART00000166449
pik3r3a
phosphoinositide-3-kinase, regulatory subunit 3a (gamma)
chr7_+_37742299 0.65 ENSDART00000143300
brd7
bromodomain containing 7
chr10_+_585719 0.64 ENSDART00000180167
smad4a
SMAD family member 4a
chr19_+_7173613 0.64 ENSDART00000001331
hsd17b8
hydroxysteroid (17-beta) dehydrogenase 8
chr7_+_32901658 0.63 ENSDART00000115420
ano9b
anoctamin 9b
chr3_-_11878490 0.63 ENSDART00000129961
coro7
coronin 7
chr20_+_2739804 0.63 ENSDART00000152655
syncrip
synaptotagmin binding, cytoplasmic RNA interacting protein
chr4_-_16876281 0.63 ENSDART00000016690
ENSDART00000044005
ENSDART00000042874
ENSDART00000125762
ENSDART00000185974
tmpoa
thymopoietin a
chr5_+_5406503 0.62 ENSDART00000124022
mapkap1
mitogen-activated protein kinase associated protein 1
chr16_+_14249546 0.62 ENSDART00000059967
polr3c
polymerase (RNA) III (DNA directed) polypeptide C
chr10_-_6494070 0.61 ENSDART00000171320
dcp2
decapping mRNA 2
chr14_+_23717165 0.61 ENSDART00000006373
ndfip1
Nedd4 family interacting protein 1
chr15_-_20731638 0.61 ENSDART00000170616
tpst1
tyrosylprotein sulfotransferase 1
chr4_+_73051901 0.61 ENSDART00000174219
zgc:152938
zgc:152938
chr11_+_5681762 0.61 ENSDART00000179139
arid3a
AT rich interactive domain 3A (BRIGHT-like)
chr11_+_25157374 0.60 ENSDART00000019450
trpc4apa
transient receptor potential cation channel, subfamily C, member 4 associated protein a
chr15_-_20731297 0.60 ENSDART00000114464
tpst1
tyrosylprotein sulfotransferase 1
chr2_+_51783120 0.59 ENSDART00000177559
crygn1
crystallin, gamma N1
chr5_+_43782267 0.59 ENSDART00000130355
nos2a
nitric oxide synthase 2a, inducible
chr5_+_31965845 0.59 ENSDART00000112968
myo1hb
myosin IHb
chr11_+_3308656 0.58 ENSDART00000082458
sarnp
SAP domain containing ribonucleoprotein
chr7_+_39054478 0.58 ENSDART00000173825
dgkza
diacylglycerol kinase, zeta a
chr5_+_27137473 0.58 ENSDART00000181833
unc5db
unc-5 netrin receptor Db
chr6_+_18544791 0.58 ENSDART00000167463
ENSDART00000169599
atad5b
ATPase family, AAA domain containing 5b
chr2_-_15324837 0.57 ENSDART00000015655
tecrl2b
trans-2,3-enoyl-CoA reductase-like 2b
chr18_-_22735002 0.57 ENSDART00000023721
nudt21
nudix hydrolase 21
chr6_+_55212928 0.57 ENSDART00000083668
manbal
mannosidase beta like
chr14_+_1170968 0.56 ENSDART00000125203
ENSDART00000193575
hopx
HOP homeobox
chr5_+_30596632 0.56 ENSDART00000051414
hinfp
histone H4 transcription factor
chr12_-_28794957 0.56 ENSDART00000020667
osbpl7
oxysterol binding protein-like 7
chr6_-_42377307 0.55 ENSDART00000129302
emc3
ER membrane protein complex subunit 3
chr17_-_33412868 0.55 ENSDART00000187521
BX323819.1

chr6_-_36795111 0.54 ENSDART00000160669
ENSDART00000104256
ENSDART00000187751
ENSDART00000161928
ENSDART00000183264
opa1
optic atrophy 1 (autosomal dominant)
chr14_-_21097574 0.54 ENSDART00000186803
rnf20
ring finger protein 20, E3 ubiquitin protein ligase
chr5_+_30596477 0.52 ENSDART00000124487
hinfp
histone H4 transcription factor
chr13_-_25819825 0.52 ENSDART00000077612
rel
v-rel avian reticuloendotheliosis viral oncogene homolog
chr8_-_48668111 0.51 ENSDART00000047134
clcn6
chloride channel 6
chr5_+_18012154 0.51 ENSDART00000139431
ENSDART00000048859
ascc2
activating signal cointegrator 1 complex subunit 2
chr2_-_37280617 0.51 ENSDART00000190458
nadkb
NAD kinase b
chr14_+_29550323 0.50 ENSDART00000157943
TENM2
si:dkey-34l15.2
chr17_-_31819837 0.50 ENSDART00000160281
abraxas2b
abraxas 2b, BRISC complex subunit
chr19_+_26922780 0.49 ENSDART00000187396
ENSDART00000188978
nelfe
negative elongation factor complex member E
chr13_-_865193 0.49 ENSDART00000187053
AL929536.7

chr20_+_9128256 0.49 ENSDART00000163883
ENSDART00000183072
ENSDART00000187276
bpnt1
bisphosphate nucleotidase 1
chr7_+_30725473 0.49 ENSDART00000085716
mtmr10
myotubularin related protein 10
chr25_+_2645488 0.49 ENSDART00000113032
adck2
aarF domain containing kinase 2
chr23_+_43770149 0.49 ENSDART00000024313
rnf150b
ring finger protein 150b
chr3_+_19685873 0.48 ENSDART00000006490
tlk2
tousled-like kinase 2
chr9_-_14683574 0.48 ENSDART00000144022
pard3bb
par-3 family cell polarity regulator beta b
chr13_-_30996072 0.48 ENSDART00000181661
wdfy4
WDFY family member 4
chr21_+_15603597 0.47 ENSDART00000138626
smarcb1b
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1b
chr5_-_55914268 0.47 ENSDART00000014049
wdr36
WD repeat domain 36
chr14_+_14043793 0.47 ENSDART00000164376
rraga
Ras-related GTP binding A
chr21_+_76739 0.47 ENSDART00000174654
ARSB
arylsulfatase B
chr12_-_10476448 0.46 ENSDART00000106172
rac1a
Rac family small GTPase 1a
chr17_+_50074372 0.45 ENSDART00000113644
vps39
vacuolar protein sorting 39 homolog (S. cerevisiae)
chr12_+_33484458 0.45 ENSDART00000000069
slc9a3r1a
solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1a
chr13_-_22699024 0.45 ENSDART00000016946
glud1a
glutamate dehydrogenase 1a
chr11_+_18873113 0.44 ENSDART00000103969
ENSDART00000103968
magi1b
membrane associated guanylate kinase, WW and PDZ domain containing 1b
chr3_+_19216567 0.43 ENSDART00000134433
il12rb2l
interleukin 12 receptor, beta 2a, like
chr6_+_40951227 0.43 ENSDART00000156660
patz1
POZ (BTB) and AT hook containing zinc finger 1
chr19_+_26923274 0.43 ENSDART00000148439
ENSDART00000148877
nelfe
negative elongation factor complex member E
chr5_+_1965296 0.43 ENSDART00000156224
dhx33
DEAH (Asp-Glu-Ala-His) box polypeptide 33
chr20_-_28884800 0.42 ENSDART00000134564
ENSDART00000132127
ENSDART00000135506
ENSDART00000075515
srsf5b
serine/arginine-rich splicing factor 5b
chr7_+_31132588 0.42 ENSDART00000173702
tjp1a
tight junction protein 1a
chr8_-_51954562 0.41 ENSDART00000132527
ENSDART00000057315
cep78
centrosomal protein 78
chr19_+_42231431 0.41 ENSDART00000102698
jtb
jumping translocation breakpoint
chr12_+_36109507 0.40 ENSDART00000175409
map2k6
mitogen-activated protein kinase kinase 6
chr24_+_35183595 0.40 ENSDART00000075142
pcmtd1
protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1
chr7_+_7511914 0.40 ENSDART00000172848
clcn3
chloride channel 3
chr8_+_13368150 0.39 ENSDART00000114699
slc5a5
solute carrier family 5 (sodium/iodide cotransporter), member 5
chr6_-_31739709 0.39 ENSDART00000087964
cachd1
cache domain containing 1

Network of associatons between targets according to the STRING database.

First level regulatory network of nkx2.2b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0090004 positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.4 1.4 GO:0002320 lymphoid progenitor cell differentiation(GO:0002320)
0.4 1.1 GO:0042730 fibrinolysis(GO:0042730)
0.3 1.1 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.2 1.2 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.2 0.9 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.2 0.9 GO:0032801 receptor catabolic process(GO:0032801)
0.2 1.3 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.2 1.1 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.2 0.7 GO:0015887 biotin transport(GO:0015878) pantothenate transmembrane transport(GO:0015887) coenzyme transport(GO:0051182)
0.2 1.1 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143) protein urmylation(GO:0032447)
0.2 1.7 GO:0045444 fat cell differentiation(GO:0045444)
0.2 1.3 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.2 0.5 GO:2000425 regulation of apoptotic cell clearance(GO:2000425)
0.2 0.9 GO:0006013 mannose metabolic process(GO:0006013)
0.2 1.2 GO:0006478 protein sulfation(GO:0006477) peptidyl-tyrosine sulfation(GO:0006478)
0.1 0.9 GO:0042795 snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.1 0.7 GO:0045056 transcytosis(GO:0045056)
0.1 1.2 GO:0060036 notochord cell vacuolation(GO:0060036)
0.1 0.9 GO:0015809 arginine transport(GO:0015809)
0.1 0.5 GO:0051660 establishment of centrosome localization(GO:0051660)
0.1 0.7 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.1 0.7 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.1 0.6 GO:0090133 establishment or maintenance of cytoskeleton polarity(GO:0030952) mesendoderm migration(GO:0090133) cell migration involved in mesendoderm migration(GO:0090134)
0.1 1.0 GO:1901678 heme transport(GO:0015886) iron coordination entity transport(GO:1901678)
0.1 0.9 GO:1902038 positive regulation of hematopoietic stem cell differentiation(GO:1902038)
0.1 0.6 GO:0031284 regulation of cGMP metabolic process(GO:0030823) positive regulation of cGMP metabolic process(GO:0030825) regulation of cGMP biosynthetic process(GO:0030826) positive regulation of cGMP biosynthetic process(GO:0030828) regulation of guanylate cyclase activity(GO:0031282) positive regulation of guanylate cyclase activity(GO:0031284)
0.1 0.5 GO:0046838 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855) inositol phosphate catabolic process(GO:0071545)
0.1 0.8 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948) reelin-mediated signaling pathway(GO:0038026)
0.1 1.1 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.1 1.0 GO:0009303 rRNA transcription(GO:0009303)
0.1 2.0 GO:0070897 DNA-templated transcriptional preinitiation complex assembly(GO:0070897)
0.1 0.6 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.1 1.4 GO:0010962 regulation of glycogen biosynthetic process(GO:0005979) regulation of glucan biosynthetic process(GO:0010962)
0.1 1.3 GO:0045048 protein insertion into ER membrane(GO:0045048)
0.1 0.9 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.1 0.5 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.1 0.3 GO:0035095 behavioral response to nicotine(GO:0035095)
0.1 1.7 GO:0015701 bicarbonate transport(GO:0015701)
0.1 1.3 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.1 1.3 GO:0008078 mesodermal cell migration(GO:0008078)
0.1 0.5 GO:0006741 NADP biosynthetic process(GO:0006741)
0.1 0.4 GO:0045943 regulation of transcription from RNA polymerase I promoter(GO:0006356) positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.1 0.6 GO:0061588 calcium activated phospholipid scrambling(GO:0061588)
0.1 1.3 GO:0008354 germ cell migration(GO:0008354)
0.1 0.6 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.1 0.3 GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.1 1.5 GO:0080111 DNA demethylation(GO:0080111)
0.1 0.4 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.1 0.4 GO:0043649 dicarboxylic acid catabolic process(GO:0043649)
0.1 0.5 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.1 0.2 GO:0042256 mature ribosome assembly(GO:0042256)
0.1 0.5 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.1 0.6 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.1 0.2 GO:0043968 histone H2A acetylation(GO:0043968)
0.1 0.2 GO:0090386 phagosome maturation involved in apoptotic cell clearance(GO:0090386) phagolysosome assembly involved in apoptotic cell clearance(GO:0090387)
0.1 1.5 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.1 1.5 GO:0006446 regulation of translational initiation(GO:0006446)
0.1 0.7 GO:0043550 regulation of lipid kinase activity(GO:0043550) regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.0 1.4 GO:0048920 posterior lateral line neuromast primordium migration(GO:0048920)
0.0 0.6 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.1 GO:0098838 folic acid transport(GO:0015884) drug transport(GO:0015893) methotrexate transport(GO:0051958) reduced folate transmembrane transport(GO:0098838)
0.0 0.4 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.0 0.9 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.0 0.8 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.0 1.4 GO:0003094 glomerular filtration(GO:0003094)
0.0 0.8 GO:1901663 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 1.9 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.0 1.3 GO:0009636 response to toxic substance(GO:0009636)
0.0 0.2 GO:0042766 nucleosome mobilization(GO:0042766)
0.0 0.4 GO:0032024 positive regulation of insulin secretion(GO:0032024)
0.0 0.2 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.0 1.6 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.8 GO:0006515 misfolded or incompletely synthesized protein catabolic process(GO:0006515)
0.0 1.4 GO:0042752 regulation of circadian rhythm(GO:0042752)
0.0 0.9 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.9 GO:0090307 mitotic spindle assembly(GO:0090307) microtubule cytoskeleton organization involved in mitosis(GO:1902850)
0.0 0.6 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.8 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 0.2 GO:0090243 fibroblast growth factor receptor signaling pathway involved in somitogenesis(GO:0090243)
0.0 0.3 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.5 GO:0010390 histone monoubiquitination(GO:0010390)
0.0 0.8 GO:0000266 mitochondrial fission(GO:0000266)
0.0 0.4 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.3 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0 0.6 GO:0048264 determination of ventral identity(GO:0048264)
0.0 0.7 GO:0048814 regulation of dendrite morphogenesis(GO:0048814)
0.0 0.9 GO:0032924 activin receptor signaling pathway(GO:0032924)
0.0 1.3 GO:0044744 protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744) single-organism nuclear import(GO:1902593)
0.0 0.3 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.9 GO:0030166 proteoglycan biosynthetic process(GO:0030166)
0.0 0.4 GO:1902622 regulation of neutrophil migration(GO:1902622)
0.0 0.5 GO:0038061 NIK/NF-kappaB signaling(GO:0038061)
0.0 0.7 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0 0.6 GO:0031398 positive regulation of protein ubiquitination(GO:0031398)
0.0 1.6 GO:0031101 fin regeneration(GO:0031101)
0.0 0.3 GO:0033135 regulation of peptidyl-serine phosphorylation(GO:0033135) positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.0 0.4 GO:0055078 sodium ion homeostasis(GO:0055078)
0.0 0.6 GO:0030050 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.0 0.9 GO:0090090 negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.0 0.7 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.0 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.0 0.1 GO:0006543 glutamate biosynthetic process(GO:0006537) glutamine catabolic process(GO:0006543)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0043034 costamere(GO:0043034)
0.3 2.0 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.3 1.5 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.2 0.6 GO:0042382 paraspeckles(GO:0042382)
0.1 1.3 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.1 1.0 GO:0035145 exon-exon junction complex(GO:0035145)
0.1 0.9 GO:0032021 NELF complex(GO:0032021)
0.1 0.5 GO:0034448 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 0.8 GO:0032783 ELL-EAF complex(GO:0032783)
0.1 1.3 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 1.6 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 0.6 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.1 1.4 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 0.5 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.1 0.9 GO:0048179 activin receptor complex(GO:0048179)
0.1 0.5 GO:0035060 brahma complex(GO:0035060)
0.1 1.3 GO:0005685 U1 snRNP(GO:0005685)
0.1 1.0 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.1 0.2 GO:0030689 Noc complex(GO:0030689)
0.1 2.3 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.5 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 4.6 GO:0055037 recycling endosome(GO:0055037)
0.0 2.3 GO:1903293 protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.0 1.9 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.6 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 1.1 GO:0043186 P granule(GO:0043186)
0.0 0.7 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.6 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.3 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.0 3.3 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.9 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 0.3 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 2.6 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.3 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.3 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 1.2 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.9 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.2 GO:0000812 Swr1 complex(GO:0000812)
0.0 1.0 GO:0005902 microvillus(GO:0005902)
0.0 0.2 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.9 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 1.2 GO:0030173 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 2.1 GO:0043296 apical junction complex(GO:0043296)
0.0 1.7 GO:0016607 nuclear speck(GO:0016607)
0.0 1.1 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.6 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.2 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202) INO80-type complex(GO:0097346)
0.0 0.3 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.5 GO:0031970 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 0.0 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.7 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 1.0 GO:0016459 myosin complex(GO:0016459)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.6 GO:0071253 connexin binding(GO:0071253)
0.3 1.3 GO:0051059 NF-kappaB binding(GO:0051059)
0.3 2.2 GO:0000995 transcription factor activity, core RNA polymerase III binding(GO:0000995)
0.3 1.5 GO:0008311 double-stranded DNA exodeoxyribonuclease activity(GO:0008309) double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.2 0.7 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.2 1.5 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.2 0.7 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.2 0.5 GO:1901612 cardiolipin binding(GO:1901612)
0.2 1.3 GO:0030619 U1 snRNA binding(GO:0030619)
0.2 1.5 GO:0008494 translation activator activity(GO:0008494)
0.2 1.2 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.1 1.0 GO:0015232 heme transporter activity(GO:0015232)
0.1 0.4 GO:0047690 aspartyltransferase activity(GO:0047690)
0.1 0.6 GO:0050699 WW domain binding(GO:0050699)
0.1 1.5 GO:0009008 DNA-methyltransferase activity(GO:0009008)
0.1 0.9 GO:0009378 four-way junction helicase activity(GO:0009378)
0.1 1.4 GO:2001069 glycogen binding(GO:2001069)
0.1 0.8 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.1 1.4 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.1 0.6 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.1 0.9 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.1 1.7 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.1 0.6 GO:0050072 m7G(5')pppN diphosphatase activity(GO:0050072)
0.1 0.4 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.1 0.9 GO:0035250 UDP-galactosyltransferase activity(GO:0035250)
0.1 1.6 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.1 1.2 GO:0003785 actin monomer binding(GO:0003785)
0.1 0.5 GO:0032977 membrane insertase activity(GO:0032977)
0.1 0.7 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 0.9 GO:0070491 repressing transcription factor binding(GO:0070491)
0.1 0.6 GO:0005042 netrin receptor activity(GO:0005042)
0.1 0.6 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.1 0.9 GO:0017002 activin-activated receptor activity(GO:0017002)
0.1 1.6 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.1 0.6 GO:0035925 AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 0.4 GO:0008118 N-acetyllactosaminide alpha-2,3-sialyltransferase activity(GO:0008118)
0.1 0.9 GO:0002039 p53 binding(GO:0002039)
0.0 0.8 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.0 0.7 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 1.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.8 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.1 GO:0015350 reduced folate carrier activity(GO:0008518) methotrexate transporter activity(GO:0015350)
0.0 0.9 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.8 GO:0072542 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.0 0.2 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 0.6 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.8 GO:0004659 prenyltransferase activity(GO:0004659)
0.0 0.6 GO:0048038 quinone binding(GO:0048038)
0.0 1.1 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 1.9 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.1 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.4 GO:0008061 chitin binding(GO:0008061)
0.0 0.9 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 2.3 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.3 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 1.1 GO:0000049 tRNA binding(GO:0000049)
0.0 0.3 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.5 GO:0008252 nucleotidase activity(GO:0008252)
0.0 0.9 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.6 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.4 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.7 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.9 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 1.5 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.3 GO:0051371 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.0 1.0 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.3 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 1.2 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 2.0 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 0.0 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.6 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.3 GO:0017069 snRNA binding(GO:0017069)
0.0 0.3 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.0 GO:0070051 fibrinogen binding(GO:0070051)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 2.6 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.1 1.4 PID RAS PATHWAY Regulation of Ras family activation
0.1 0.4 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 1.1 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.4 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.9 PID ATM PATHWAY ATM pathway
0.0 1.9 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.7 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.5 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.5 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.3 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.0 1.1 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.9 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.2 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.5 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.7 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.9 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.1 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 1.5 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.1 0.5 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 1.1 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 1.2 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 1.5 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.1 1.5 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1 0.8 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.1 1.3 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.1 0.9 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.1 0.5 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 0.7 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.6 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 1.5 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.9 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.9 REACTOME KINESINS Genes involved in Kinesins
0.0 0.4 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.9 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.0 0.4 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.9 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 1.2 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.0 2.0 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.9 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.3 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.4 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.4 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.0 0.3 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.1 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.4 REACTOME MYOGENESIS Genes involved in Myogenesis