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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for nkx6.1

Z-value: 0.77

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Transcription factors associated with nkx6.1

Gene Symbol Gene ID Gene Info
nkx6.1
ENSDARG00000022569 NK6 homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nkx6.1dr11_v1_chr21_+_19070921_190709210.719.1e-04Click!

Activity profile of nkx6.1 motif

Sorted Z-values of nkx6.1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr17_+_21295132 3.42 ENSDART00000103845
eno4
enolase family member 4
chr5_+_6954162 2.72 ENSDART00000086666
stpg2
sperm-tail PG-rich repeat containing 2
chr15_+_34988148 2.43 ENSDART00000076269
ccdc105
coiled-coil domain containing 105
chr17_+_15433518 1.91 ENSDART00000026180
fabp7a
fatty acid binding protein 7, brain, a
chr23_-_23401305 1.80 ENSDART00000078936
her9
hairy-related 9
chr6_-_40352215 1.75 ENSDART00000103992
ttll3
tubulin tyrosine ligase-like family, member 3
chr15_-_20933574 1.72 ENSDART00000152648
ENSDART00000152448
ENSDART00000152244
usp2a
ubiquitin specific peptidase 2a
chr17_+_15433671 1.69 ENSDART00000149568
fabp7a
fatty acid binding protein 7, brain, a
chr15_-_4528326 1.68 ENSDART00000158122
ENSDART00000155619
ENSDART00000128602
tfdp2
transcription factor Dp-2
chr16_-_31974482 1.65 ENSDART00000189073
styk1
serine/threonine/tyrosine kinase 1
chr24_+_17269849 1.59 ENSDART00000017605
spag6
sperm associated antigen 6
chr3_+_17537352 1.59 ENSDART00000104549
hcrt
hypocretin (orexin) neuropeptide precursor
chr25_-_16581233 1.59 ENSDART00000155312
smc1b
structural maintenance of chromosomes 1B
chr19_-_3931917 1.56 ENSDART00000162532
map7d1b
MAP7 domain containing 1b
chr12_-_35830625 1.55 ENSDART00000180028
CU459056.1

chr4_+_72723304 1.49 ENSDART00000186791
ENSDART00000158902
ENSDART00000191925
rab3ip
RAB3A interacting protein (rabin3)
chr20_-_31075972 1.49 ENSDART00000122927
si:ch211-198b3.4
si:ch211-198b3.4
chr11_-_37997419 1.47 ENSDART00000102870
slc41a1
solute carrier family 41 (magnesium transporter), member 1
chr22_-_547748 1.45 ENSDART00000037455
ENSDART00000140101
ccnd3
cyclin D3
chr20_-_52631998 1.45 ENSDART00000145283
ENSDART00000139072
si:ch211-221n20.1
si:ch211-221n20.1
chr10_+_22381802 1.42 ENSDART00000112484
nlgn2b
neuroligin 2b
chr7_-_28148310 1.42 ENSDART00000044208
lmo1
LIM domain only 1
chr11_+_25257022 1.34 ENSDART00000156052
tp53inp2
tumor protein p53 inducible nuclear protein 2
chr3_+_28953274 1.33 ENSDART00000133528
ENSDART00000103602
lgals2a
lectin, galactoside-binding, soluble, 2a
chr19_+_32166702 1.33 ENSDART00000021798
fabp11a
fatty acid binding protein 11a
chr16_-_42056137 1.32 ENSDART00000102798
zp3d.2
zona pellucida glycoprotein 3d tandem duplicate 2
chr1_-_44933094 1.30 ENSDART00000147527
si:dkey-9i23.14
si:dkey-9i23.14
chr9_-_1702648 1.30 ENSDART00000102934
hnrnpa3
heterogeneous nuclear ribonucleoprotein A3
chr24_+_40860320 1.27 ENSDART00000161351
gorasp1b
golgi reassembly stacking protein 1b
chr8_+_49117518 1.26 ENSDART00000079631
rad21l1
RAD21 cohesin complex component like 1
chr1_+_55239160 1.25 ENSDART00000152318
si:ch211-286b5.2
si:ch211-286b5.2
chr23_+_39695827 1.24 ENSDART00000113893
ENSDART00000186679
tmco4
transmembrane and coiled-coil domains 4
chr16_+_25126935 1.22 ENSDART00000058945
zgc:92590
zgc:92590
chr1_+_52662203 1.20 ENSDART00000141530
osbp
oxysterol binding protein
chr3_+_13929860 1.17 ENSDART00000164179
syce2
synaptonemal complex central element protein 2
chr11_+_33818179 1.16 ENSDART00000109418
spoplb
speckle-type POZ protein-like b
chr1_+_52929185 1.15 ENSDART00000147683
inpp4b
inositol polyphosphate-4-phosphatase type II B
chr15_-_20024205 1.12 ENSDART00000161379
auts2b
autism susceptibility candidate 2b
chr22_+_18187857 1.11 ENSDART00000166300
mef2b
myocyte enhancer factor 2b
chr23_+_6795709 1.07 ENSDART00000149136
si:ch211-117c9.5
si:ch211-117c9.5
chr13_+_31402067 1.07 ENSDART00000019202
tdrd9
tudor domain containing 9
chr3_-_40202607 1.07 ENSDART00000074757
znf598
zinc finger protein 598
chr1_+_50538839 1.06 ENSDART00000020412
pkd2
polycystic kidney disease 2
chr13_+_22295905 1.06 ENSDART00000180133
ENSDART00000181125
usp54a
ubiquitin specific peptidase 54a
chr10_+_39084354 1.05 ENSDART00000158245
si:ch73-1a9.3
si:ch73-1a9.3
chr19_+_31904836 1.05 ENSDART00000162297
ENSDART00000088340
ENSDART00000151280
ENSDART00000151218
tpd52
tumor protein D52
chr18_+_19456648 1.04 ENSDART00000079695
zwilch
zwilch kinetochore protein
chr10_-_26512993 1.03 ENSDART00000188549
ENSDART00000193316
si:dkey-5g14.1
si:dkey-5g14.1
chr23_+_31245395 1.03 ENSDART00000053588
irak1bp1
interleukin-1 receptor-associated kinase 1 binding protein 1
chr24_+_17270129 1.02 ENSDART00000186729
spag6
sperm associated antigen 6
chr7_-_20103384 1.02 ENSDART00000052902
acap1
ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
chr10_+_6884627 1.02 ENSDART00000125262
ENSDART00000121729
ENSDART00000105384
ddx4
DEAD (Asp-Glu-Ala-Asp) box polypeptide 4
chr18_+_3037998 1.01 ENSDART00000185844
ENSDART00000162657
rps3
ribosomal protein S3
chr16_+_46111849 0.99 ENSDART00000172232
sv2a
synaptic vesicle glycoprotein 2A
chr20_-_14925281 0.99 ENSDART00000152641
dnm3a
dynamin 3a
chr14_-_2933185 0.99 ENSDART00000161677
ENSDART00000162446
ENSDART00000109378
si:dkey-201i24.6
si:dkey-201i24.6
chr18_-_19456269 0.96 ENSDART00000060363
rpl4
ribosomal protein L4
chr22_+_18188045 0.96 ENSDART00000140106
mef2b
myocyte enhancer factor 2b
chr15_-_15983183 0.96 ENSDART00000154841
synrg
synergin, gamma
chr6_-_7720332 0.95 ENSDART00000135945
rpsa
ribosomal protein SA
chr9_-_20372977 0.95 ENSDART00000113418
igsf3
immunoglobulin superfamily, member 3
chr16_-_42894628 0.94 ENSDART00000045600
hfe2
hemochromatosis type 2
chr17_+_6625717 0.91 ENSDART00000190753
ENSDART00000181298
BX005321.1

chr8_-_17167819 0.90 ENSDART00000135042
ENSDART00000143920
mrps36
mitochondrial ribosomal protein S36
chr7_-_28147838 0.90 ENSDART00000158921
lmo1
LIM domain only 1
chr21_+_45502621 0.90 ENSDART00000166719
si:dkey-223p19.2
si:dkey-223p19.2
chr17_-_29119362 0.90 ENSDART00000104204
foxg1a
forkhead box G1a
chr6_+_3280939 0.89 ENSDART00000151359
kdm4aa
lysine (K)-specific demethylase 4A, genome duplicate a
chr24_-_26399623 0.89 ENSDART00000112317
zgc:194621
zgc:194621
chr14_+_14662116 0.88 ENSDART00000161693
cetn2
centrin, EF-hand protein, 2
chr12_+_20352400 0.87 ENSDART00000066383
hbae5
hemoglobin, alpha embryonic 5
chr22_+_35068046 0.87 ENSDART00000161660
ENSDART00000169573
si:ch73-173h19.3
si:ch73-173h19.3
chr24_+_12989727 0.85 ENSDART00000126842
ENSDART00000129309
flj11011l
hypothetical protein FLJ11011-like (H. sapiens)
chr20_-_14924858 0.85 ENSDART00000047039
dnm3a
dynamin 3a
chr1_-_49434798 0.84 ENSDART00000150842
ENSDART00000150789
ATP5MD
si:dkeyp-80c12.10
chr7_+_14291323 0.84 ENSDART00000053521
rhcga
Rh family, C glycoprotein a
chr20_+_27691307 0.84 ENSDART00000153299
si:dkey-1h6.8
si:dkey-1h6.8
chr23_+_23020709 0.84 ENSDART00000146463
samd11
sterile alpha motif domain containing 11
chr14_+_45471642 0.84 ENSDART00000126979
ENSDART00000172952
ENSDART00000173284
ubxn1
UBX domain protein 1
chr16_+_42481447 0.84 ENSDART00000037401
herpud2
HERPUD family member 2
chr4_+_20177526 0.83 ENSDART00000017947
ENSDART00000135451
ccdc146
coiled-coil domain containing 146
chr11_+_26604224 0.83 ENSDART00000030453
ENSDART00000168895
ENSDART00000159505
dynlrb1
dynein, light chain, roadblock-type 1
chr11_-_41853874 0.83 ENSDART00000002556
mrto4
MRT4 homolog, ribosome maturation factor
chr11_-_438294 0.83 ENSDART00000040812
nuf2
NUF2, NDC80 kinetochore complex component, homolog
chr15_+_41027466 0.82 ENSDART00000075940
mtnr1ba
melatonin receptor type 1Ba
chr16_+_42482270 0.82 ENSDART00000184225
herpud2
HERPUD family member 2
chr1_-_44704261 0.82 ENSDART00000133210
si:dkey-28b4.8
si:dkey-28b4.8
chr22_-_13042992 0.81 ENSDART00000028787
ahr1b
aryl hydrocarbon receptor 1b
chr8_+_21384288 0.81 ENSDART00000079263
fhad1
forkhead-associated (FHA) phosphopeptide binding domain 1
chr4_-_779796 0.81 ENSDART00000128743
tmem214
transmembrane protein 214
chr5_-_34185115 0.80 ENSDART00000192771
fibcd1
fibrinogen C domain containing 1
chr9_-_21382190 0.79 ENSDART00000110943
ENSDART00000188129
ENSDART00000193876
ift88
intraflagellar transport 88 homolog
chr1_-_44701313 0.79 ENSDART00000193926
si:dkey-28b4.8
si:dkey-28b4.8
chr16_-_28878080 0.79 ENSDART00000149501
si:dkey-239n17.4
si:dkey-239n17.4
chr8_+_26522013 0.79 ENSDART00000046863
sema3bl
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3bl
chr7_+_38510197 0.78 ENSDART00000173468
ENSDART00000100479
slc7a9
solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
chr20_-_52338782 0.78 ENSDART00000109735
ENSDART00000132941
si:ch1073-287p18.1
si:ch1073-287p18.1
chr3_+_18555899 0.77 ENSDART00000163036
ENSDART00000158791
cbx4
chromobox homolog 4 (Pc class homolog, Drosophila)
chr10_-_24371312 0.77 ENSDART00000149362
pitpnab
phosphatidylinositol transfer protein, alpha b
chr6_+_41191482 0.77 ENSDART00000000877
opn1mw3
opsin 1 (cone pigments), medium-wave-sensitive, 3
chr20_+_4060839 0.76 ENSDART00000178565
TRIM67
tripartite motif containing 67
chr24_+_9412450 0.75 ENSDART00000132724
si:ch211-285f17.1
si:ch211-285f17.1
chr21_+_30355767 0.75 ENSDART00000189948
CR749164.1

chr10_+_2899108 0.75 ENSDART00000147031
erap1a
endoplasmic reticulum aminopeptidase 1a
chr9_-_30576522 0.74 ENSDART00000101085
morc3a
MORC family CW-type zinc finger 3a
chr18_-_48550426 0.74 ENSDART00000145189
kcnj1a.1
potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 1
chr2_-_51644044 0.73 ENSDART00000157899
dad1
defender against cell death 1
chr1_-_46244523 0.72 ENSDART00000143908
si:ch211-138g9.3
si:ch211-138g9.3
chr13_+_25449681 0.72 ENSDART00000101328
atoh7
atonal bHLH transcription factor 7
chr19_+_19786117 0.72 ENSDART00000167757
ENSDART00000163546
hoxa1a
homeobox A1a
chr16_+_33902006 0.72 ENSDART00000161807
ENSDART00000159474
gnl2
guanine nucleotide binding protein-like 2 (nucleolar)
chr8_+_41037541 0.72 ENSDART00000129344
gpat2
glycerol-3-phosphate acyltransferase 2, mitochondrial
chr17_+_31611854 0.72 ENSDART00000011706
adprhl2
ADP-ribosylhydrolase like 2
chrM_+_9735 0.71 ENSDART00000093613
mt-co3
cytochrome c oxidase III, mitochondrial
chr3_+_62161184 0.71 ENSDART00000090370
ENSDART00000192665
noxo1a
NADPH oxidase organizer 1a
chr21_-_22827548 0.71 ENSDART00000079161
angptl5
angiopoietin-like 5
chr23_+_37955041 0.71 ENSDART00000087148
cbln4
cerebellin 4 precursor
chr23_+_40460333 0.71 ENSDART00000184658
soga3b
SOGA family member 3b
chr6_+_9204099 0.70 ENSDART00000150167
ENSDART00000115394
tbx19
T-box 19
chr18_+_26422124 0.70 ENSDART00000060245
ctsh
cathepsin H
chr19_-_5103141 0.69 ENSDART00000150952
tpi1a
triosephosphate isomerase 1a
chr8_+_7144066 0.69 ENSDART00000146306
slc6a6a
solute carrier family 6 (neurotransmitter transporter), member 6a
chr2_-_23004286 0.69 ENSDART00000134664
ENSDART00000110373
ENSDART00000185833
ENSDART00000187235
znf414
mllt1b
zinc finger protein 414
MLLT1, super elongation complex subunit b
chr20_+_2134816 0.68 ENSDART00000039249
l3mbtl3
l(3)mbt-like 3 (Drosophila)
chr22_+_38037530 0.68 ENSDART00000012212
commd2
COMM domain containing 2
chr23_+_21638258 0.68 ENSDART00000104188
igsf21b
immunoglobin superfamily, member 21b
chr6_-_37469775 0.67 ENSDART00000156546
plcxd1
phosphatidylinositol-specific phospholipase C, X domain containing 1
chr12_-_10409961 0.67 ENSDART00000149521
ENSDART00000052001
eef2k
eukaryotic elongation factor 2 kinase
chr18_-_48755037 0.67 ENSDART00000109673
tirap
toll-interleukin 1 receptor (TIR) domain containing adaptor protein
chr19_-_5103313 0.66 ENSDART00000037007
tpi1a
triosephosphate isomerase 1a
chr10_+_6884123 0.66 ENSDART00000149095
ENSDART00000148772
ENSDART00000149334
ddx4
DEAD (Asp-Glu-Ala-Asp) box polypeptide 4
chr20_+_33294428 0.65 ENSDART00000024104
mycn
MYCN proto-oncogene, bHLH transcription factor
chr2_+_54641644 0.65 ENSDART00000027313
ndufv2
NADH dehydrogenase (ubiquinone) flavoprotein 2
chr13_+_21768447 0.65 ENSDART00000100941
chchd1
coiled-coil-helix-coiled-coil-helix domain containing 1
chr20_-_9095105 0.64 ENSDART00000140792
oma1
OMA1 zinc metallopeptidase
chr9_-_9415000 0.64 ENSDART00000146210
si:ch211-214p13.9
si:ch211-214p13.9
chr4_-_2545310 0.64 ENSDART00000150619
ENSDART00000140760
e2f7
E2F transcription factor 7
chr25_+_19739665 0.63 ENSDART00000067353
zgc:101783
zgc:101783
chr19_-_31402429 0.63 ENSDART00000137292
tmem106bb
transmembrane protein 106Bb
chr1_-_19502322 0.63 ENSDART00000181888
ENSDART00000044030
kitb
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog b
chr7_+_25059845 0.62 ENSDART00000077215
ppp2r5b
protein phosphatase 2, regulatory subunit B', beta
chr11_-_45138857 0.62 ENSDART00000166501
cant1b
calcium activated nucleotidase 1b
chr3_-_13461361 0.62 ENSDART00000080807
fbxw9
F-box and WD repeat domain containing 9
chr16_+_23961276 0.62 ENSDART00000192754
apoeb
apolipoprotein Eb
chr12_+_35046704 0.61 ENSDART00000105523
ENSDART00000149946
timm23a
translocase of inner mitochondrial membrane 23 homolog a (yeast)
chr9_-_12424791 0.61 ENSDART00000135447
ENSDART00000088199
zgc:162707
zgc:162707
chr25_-_3470910 0.61 ENSDART00000029067
ENSDART00000186737
hbp1
HMG-box transcription factor 1
chr2_-_55298075 0.61 ENSDART00000186404
ENSDART00000149062
rab8a
RAB8A, member RAS oncogene family
chr2_-_10338759 0.61 ENSDART00000150166
ENSDART00000149584
gng12a
guanine nucleotide binding protein (G protein), gamma 12a
chr2_+_20793982 0.61 ENSDART00000014785
prg4a
proteoglycan 4a
chr22_-_18387059 0.61 ENSDART00000007769
tssk6
testis-specific serine kinase 6
chr13_-_45475289 0.60 ENSDART00000043345
rsrp1
arginine/serine-rich protein 1
chr2_+_38147761 0.60 ENSDART00000135307
sall2
spalt-like transcription factor 2
chr4_-_22472653 0.60 ENSDART00000066903
ENSDART00000130072
ENSDART00000123369
kmt2e
lysine (K)-specific methyltransferase 2E
chr23_+_20110086 0.60 ENSDART00000054664
tnnc1b
troponin C type 1b (slow)
chr1_-_5455498 0.59 ENSDART00000040368
ENSDART00000114035
mnx2b
motor neuron and pancreas homeobox 2b
chr1_-_31171242 0.59 ENSDART00000190294
kcnq5b
potassium voltage-gated channel, KQT-like subfamily, member 5b
chr12_-_19007834 0.59 ENSDART00000153248
chadlb
chondroadherin-like b
chr3_+_57038033 0.59 ENSDART00000162930
bahcc1a
BAH domain and coiled-coil containing 1a
chr19_-_44065581 0.59 ENSDART00000006338
mterf3
mitochondrial transcription termination factor 3
chr12_+_35654749 0.59 ENSDART00000169889
ENSDART00000167873
baiap2b
BAI1-associated protein 2b
chr7_+_20471315 0.58 ENSDART00000173714
si:dkey-19b23.13
si:dkey-19b23.13
chr5_+_19343880 0.58 ENSDART00000148130
acacb
acetyl-CoA carboxylase beta
chr10_+_29698467 0.58 ENSDART00000163402
dlg2
discs, large homolog 2 (Drosophila)
chr21_+_18925318 0.57 ENSDART00000136182
si:ch211-222n4.2
si:ch211-222n4.2
chr9_-_3671911 0.57 ENSDART00000102900
sp5a
Sp5 transcription factor a
chr13_+_27232848 0.56 ENSDART00000138043
rin2
Ras and Rab interactor 2
chr5_+_63668735 0.56 ENSDART00000134261
ENSDART00000097330
dnm1b
dynamin 1b
chr13_+_4225173 0.56 ENSDART00000058242
ENSDART00000143456
mea1
male-enhanced antigen 1
chr19_+_12444943 0.56 ENSDART00000135706
ldlrad4a
low density lipoprotein receptor class A domain containing 4a
chr15_-_23376541 0.56 ENSDART00000078570
c1qtnf5
C1q and TNF related 5
chr11_-_2478374 0.56 ENSDART00000173205
si:ch73-267c23.10
si:ch73-267c23.10
chr21_-_40676224 0.55 ENSDART00000162623
arxb
aristaless related homeobox b
chr1_+_12767318 0.55 ENSDART00000162652
pcdh10a
protocadherin 10a
chr21_+_28445052 0.55 ENSDART00000077871
pygma
phosphorylase, glycogen, muscle A
chr15_-_46821568 0.55 ENSDART00000148525
chrd
chordin
chr8_-_45760087 0.55 ENSDART00000025620
ppiaa
peptidylprolyl isomerase Aa (cyclophilin A)
chr10_+_36026576 0.54 ENSDART00000193786
hmgb1a
high mobility group box 1a
chr22_-_13851297 0.54 ENSDART00000080306
s100b
S100 calcium binding protein, beta (neural)
chr22_-_834106 0.54 ENSDART00000105873
cry4
cryptochrome circadian clock 4
chr2_-_30668580 0.54 ENSDART00000087270
ctnnd2b
catenin (cadherin-associated protein), delta 2b
chr9_+_40874194 0.53 ENSDART00000141548
hibch
3-hydroxyisobutyryl-CoA hydrolase
chr7_-_25895189 0.52 ENSDART00000173599
ENSDART00000079235
ENSDART00000173786
ENSDART00000173602
ENSDART00000079245
ENSDART00000187568
ENSDART00000173505
cd99l2
CD99 molecule-like 2
chr3_-_31618037 0.52 ENSDART00000183547
moto
minamoto
chr9_+_14291932 0.51 ENSDART00000183119
BX511082.1

chr8_-_34762163 0.51 ENSDART00000114080
setd1bb
SET domain containing 1B, b
chr1_-_26063188 0.51 ENSDART00000168640
pdcd4a
programmed cell death 4a
chr3_-_39696066 0.51 ENSDART00000015393
b9d1
B9 protein domain 1
chr24_+_12945803 0.51 ENSDART00000005105
psme1
proteasome activator subunit 1
chr3_-_13146631 0.50 ENSDART00000172460
prkar1b
protein kinase, cAMP-dependent, regulatory, type I, beta
chr11_+_35050253 0.50 ENSDART00000124800
fam212aa
family with sequence similarity 212, member Aa
chr17_-_24916889 0.50 ENSDART00000156157
si:ch211-195o20.7
si:ch211-195o20.7
chr15_-_5742531 0.50 ENSDART00000045985
phkg1a
phosphorylase kinase, gamma 1a (muscle)
chr22_-_15578402 0.50 ENSDART00000062986
hsh2d
hematopoietic SH2 domain containing
chr23_+_20689255 0.50 ENSDART00000182420
usp21
ubiquitin specific peptidase 21
chr20_+_18551657 0.50 ENSDART00000147001
si:dkeyp-72h1.1
si:dkeyp-72h1.1
chr3_+_46635527 0.50 ENSDART00000153971
si:dkey-248g21.1
si:dkey-248g21.1
chr19_-_25427255 0.50 ENSDART00000036854
glcci1a
glucocorticoid induced 1a
chr14_-_17563773 0.49 ENSDART00000082667
fgfrl1a
fibroblast growth factor receptor like 1a
chr1_+_22174251 0.49 ENSDART00000137429
dnah6
dynein, axonemal, heavy chain 6

Network of associatons between targets according to the STRING database.

First level regulatory network of nkx6.1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.4 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.4 1.6 GO:0042755 eating behavior(GO:0042755)
0.4 1.1 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.4 1.1 GO:0071498 cellular response to fluid shear stress(GO:0071498)
0.3 1.4 GO:0019242 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.3 0.8 GO:0060785 regulation of apoptosis involved in tissue homeostasis(GO:0060785)
0.2 1.6 GO:0007141 male meiosis I(GO:0007141)
0.2 0.6 GO:0034382 chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830) intermediate-density lipoprotein particle clearance(GO:0071831)
0.2 0.5 GO:0052575 carbohydrate localization(GO:0052575) carbohydrate storage(GO:0052576)
0.2 0.7 GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448)
0.2 0.5 GO:0016045 detection of biotic stimulus(GO:0009595) detection of bacterium(GO:0016045) detection of other organism(GO:0098543) detection of external biotic stimulus(GO:0098581)
0.2 0.6 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
0.1 0.6 GO:0061668 mitochondrial ribosome assembly(GO:0061668)
0.1 1.3 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.1 0.6 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.1 0.6 GO:0018008 N-terminal protein myristoylation(GO:0006499) N-terminal peptidyl-glycine N-myristoylation(GO:0018008) protein myristoylation(GO:0018377)
0.1 2.4 GO:0007130 synaptonemal complex assembly(GO:0007130) synaptonemal complex organization(GO:0070193)
0.1 1.5 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.1 1.4 GO:0097105 presynaptic membrane organization(GO:0097090) postsynaptic membrane assembly(GO:0097104) presynaptic membrane assembly(GO:0097105)
0.1 0.6 GO:0032875 regulation of DNA endoreduplication(GO:0032875) positive regulation of DNA endoreduplication(GO:0032877) DNA endoreduplication(GO:0042023)
0.1 2.4 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.1 1.0 GO:0043584 nose development(GO:0043584)
0.1 0.4 GO:0006145 purine nucleobase catabolic process(GO:0006145)
0.1 0.4 GO:0045601 regulation of endothelial cell differentiation(GO:0045601)
0.1 2.2 GO:0031397 negative regulation of protein ubiquitination(GO:0031397)
0.1 1.0 GO:0072395 signal transduction involved in cell cycle checkpoint(GO:0072395)
0.1 0.3 GO:0003249 cell proliferation involved in heart valve morphogenesis(GO:0003249) regulation of cell proliferation involved in heart valve morphogenesis(GO:0003250) endocardial cell development(GO:0060958) cell proliferation involved in heart valve development(GO:2000793)
0.1 0.6 GO:0010990 SMAD protein complex assembly(GO:0007183) regulation of SMAD protein complex assembly(GO:0010990) negative regulation of SMAD protein complex assembly(GO:0010991)
0.1 0.5 GO:0010159 specification of organ position(GO:0010159)
0.1 0.6 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.1 0.8 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.1 0.3 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.1 0.7 GO:1990511 piRNA biosynthetic process(GO:1990511)
0.1 0.3 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.1 0.4 GO:0099543 trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by nitric oxide(GO:0099548)
0.1 1.3 GO:0090303 positive regulation of wound healing(GO:0090303)
0.1 0.8 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.1 0.4 GO:0003261 cardiac muscle progenitor cell migration to the midline involved in heart field formation(GO:0003261)
0.1 0.5 GO:0006574 valine catabolic process(GO:0006574)
0.1 1.9 GO:0030183 B cell differentiation(GO:0030183)
0.1 0.4 GO:0030308 negative regulation of cell growth(GO:0030308)
0.1 0.3 GO:0021846 cell proliferation in forebrain(GO:0021846)
0.1 1.6 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.1 0.6 GO:0033278 cell proliferation in midbrain(GO:0033278)
0.1 0.5 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.1 0.6 GO:1990845 adaptive thermogenesis(GO:1990845)
0.1 1.7 GO:0008406 gonad development(GO:0008406)
0.1 0.4 GO:0006691 leukotriene metabolic process(GO:0006691) leukotriene biosynthetic process(GO:0019370)
0.1 0.6 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.1 0.7 GO:0019883 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.1 0.2 GO:0046351 sucrose metabolic process(GO:0005985) sucrose biosynthetic process(GO:0005986) disaccharide biosynthetic process(GO:0046351)
0.1 0.2 GO:0070589 cell wall biogenesis(GO:0042546) cell wall macromolecule biosynthetic process(GO:0044038) cellular component macromolecule biosynthetic process(GO:0070589)
0.1 0.3 GO:0097066 response to thyroid hormone(GO:0097066)
0.1 0.2 GO:0021960 anterior commissure morphogenesis(GO:0021960)
0.1 0.3 GO:0098586 cytoplasmic pattern recognition receptor signaling pathway in response to virus(GO:0039528) cellular response to virus(GO:0098586)
0.1 0.1 GO:0030326 embryonic limb morphogenesis(GO:0030326)
0.1 0.7 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 0.4 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.1 0.2 GO:0019557 formate metabolic process(GO:0015942) histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.1 0.2 GO:0021877 forebrain neuron fate commitment(GO:0021877)
0.1 0.4 GO:0046959 nonassociative learning(GO:0046958) habituation(GO:0046959)
0.0 0.6 GO:0061300 cerebellum vasculature development(GO:0061300)
0.0 0.5 GO:1904071 presynaptic active zone assembly(GO:1904071)
0.0 0.2 GO:0071276 cellular response to cadmium ion(GO:0071276)
0.0 0.2 GO:0002159 desmosome assembly(GO:0002159)
0.0 1.0 GO:2001235 positive regulation of apoptotic signaling pathway(GO:2001235)
0.0 1.3 GO:0010508 positive regulation of autophagy(GO:0010508)
0.0 0.2 GO:0099509 regulation of presynaptic cytosolic calcium ion concentration(GO:0099509) regulation of long-term synaptic potentiation(GO:1900271)
0.0 0.4 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.4 GO:0016576 histone dephosphorylation(GO:0016576) negative regulation of signal transduction in absence of ligand(GO:1901099) regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001239) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.0 0.3 GO:0046294 formaldehyde metabolic process(GO:0046292) formaldehyde catabolic process(GO:0046294)
0.0 0.3 GO:0032732 positive regulation of interleukin-1 production(GO:0032732)
0.0 0.2 GO:0051012 microtubule sliding(GO:0051012)
0.0 0.6 GO:0032418 lysosome localization(GO:0032418)
0.0 0.3 GO:1900118 negative regulation of execution phase of apoptosis(GO:1900118) regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.9 GO:0015671 oxygen transport(GO:0015671)
0.0 0.1 GO:0035773 insulin secretion involved in cellular response to glucose stimulus(GO:0035773) regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.0 0.3 GO:0051013 microtubule severing(GO:0051013)
0.0 1.0 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.2 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.5 GO:0021592 fourth ventricle development(GO:0021592)
0.0 1.5 GO:0051904 melanosome transport(GO:0032402) pigment granule transport(GO:0051904)
0.0 0.1 GO:0015824 proline transport(GO:0015824)
0.0 0.3 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.2 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.0 0.2 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.0 1.7 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 0.5 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.6 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.8 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.1 GO:0003245 growth involved in heart morphogenesis(GO:0003241) cardiac chamber ballooning(GO:0003242) cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.0 0.1 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.0 0.6 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.5 GO:0051967 negative regulation of cytosolic calcium ion concentration(GO:0051481) negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.5 GO:0009409 response to cold(GO:0009409)
0.0 0.6 GO:0007622 rhythmic behavior(GO:0007622) circadian behavior(GO:0048512)
0.0 1.9 GO:0035082 axoneme assembly(GO:0035082)
0.0 0.2 GO:1900145 nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145)
0.0 0.5 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.2 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.0 0.1 GO:0001977 renal system process involved in regulation of blood volume(GO:0001977) renal system process involved in regulation of systemic arterial blood pressure(GO:0003071) regulation of glomerular filtration(GO:0003093) regulation of renal system process(GO:0098801)
0.0 0.5 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.9 GO:0007099 centriole replication(GO:0007099)
0.0 0.4 GO:0006285 base-excision repair, AP site formation(GO:0006285)
0.0 0.3 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.0 0.4 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 1.5 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 0.5 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 0.5 GO:0008595 tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.0 0.6 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.6 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.1 GO:1901492 positive regulation of lymphangiogenesis(GO:1901492)
0.0 0.2 GO:0097341 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.0 0.7 GO:0006801 superoxide metabolic process(GO:0006801)
0.0 0.1 GO:0060898 eye field cell fate commitment involved in camera-type eye formation(GO:0060898)
0.0 0.9 GO:0035118 embryonic pectoral fin morphogenesis(GO:0035118)
0.0 0.4 GO:0034198 cellular response to amino acid starvation(GO:0034198)
0.0 0.1 GO:0060292 long term synaptic depression(GO:0060292)
0.0 0.2 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 2.8 GO:0016579 protein deubiquitination(GO:0016579)
0.0 0.3 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.2 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.7 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.9 GO:0033339 pectoral fin development(GO:0033339)
0.0 0.5 GO:2000045 regulation of G1/S transition of mitotic cell cycle(GO:2000045)
0.0 0.2 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.2 GO:0019747 regulation of isoprenoid metabolic process(GO:0019747) regulation of vitamin metabolic process(GO:0030656) regulation of retinoic acid biosynthetic process(GO:1900052)
0.0 1.1 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.3 GO:0060038 cardiac muscle cell proliferation(GO:0060038)
0.0 0.9 GO:0043648 dicarboxylic acid metabolic process(GO:0043648)
0.0 0.3 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.7 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.1 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.0 0.4 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 0.5 GO:0072015 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.0 0.3 GO:2000601 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.5 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.2 GO:1902866 regulation of neural retina development(GO:0061074) regulation of retina development in camera-type eye(GO:1902866)
0.0 0.9 GO:0007173 epidermal growth factor receptor signaling pathway(GO:0007173)
0.0 0.1 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.0 0.1 GO:0014004 microglia differentiation(GO:0014004)
0.0 1.8 GO:0050768 negative regulation of neurogenesis(GO:0050768)
0.0 1.9 GO:0048511 rhythmic process(GO:0048511)
0.0 0.3 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.7 GO:0036269 swimming behavior(GO:0036269)
0.0 0.4 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.0 0.7 GO:1990573 potassium ion import(GO:0010107) potassium ion import across plasma membrane(GO:1990573)
0.0 0.1 GO:0006004 fucose metabolic process(GO:0006004)
0.0 0.6 GO:0048484 enteric nervous system development(GO:0048484)
0.0 0.2 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.0 0.1 GO:0042304 regulation of fatty acid biosynthetic process(GO:0042304)
0.0 0.8 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.3 GO:0032526 response to retinoic acid(GO:0032526)
0.0 0.2 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.2 GO:0060974 cell migration involved in heart formation(GO:0060974)
0.0 0.4 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.2 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.0 0.4 GO:0007586 digestion(GO:0007586)
0.0 0.2 GO:0007634 optokinetic behavior(GO:0007634)
0.0 0.2 GO:0048570 notochord morphogenesis(GO:0048570)
0.0 0.1 GO:0015804 neutral amino acid transport(GO:0015804)
0.0 0.1 GO:0031641 regulation of myelination(GO:0031641)
0.0 0.3 GO:0006829 zinc II ion transport(GO:0006829)
0.0 0.3 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.4 GO:0014003 oligodendrocyte development(GO:0014003)
0.0 0.4 GO:0090307 mitotic spindle assembly(GO:0090307) microtubule cytoskeleton organization involved in mitosis(GO:1902850)
0.0 0.6 GO:0006096 glycolytic process(GO:0006096)
0.0 0.2 GO:0015858 nucleoside transport(GO:0015858) nucleoside transmembrane transport(GO:1901642)
0.0 0.1 GO:0010460 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996) positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321) positive regulation of heart rate(GO:0010460)
0.0 0.2 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 1.6 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.0 0.1 GO:0070208 protein heterotrimerization(GO:0070208)
0.0 0.6 GO:0001764 neuron migration(GO:0001764)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0060077 inhibitory synapse(GO:0060077)
0.4 3.4 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.4 1.5 GO:0070319 Golgi to plasma membrane transport vesicle(GO:0070319)
0.3 0.9 GO:0030062 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.2 2.8 GO:0030893 meiotic cohesin complex(GO:0030893)
0.2 1.2 GO:0000801 central element(GO:0000801)
0.2 0.6 GO:0019815 B cell receptor complex(GO:0019815)
0.2 0.6 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.1 0.4 GO:0005828 kinetochore microtubule(GO:0005828)
0.1 0.8 GO:0031262 Ndc80 complex(GO:0031262)
0.1 0.5 GO:0008537 proteasome activator complex(GO:0008537)
0.1 2.4 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.1 2.8 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 2.7 GO:0043186 P granule(GO:0043186)
0.1 1.2 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 0.9 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.1 0.8 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 1.6 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.1 0.8 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 0.5 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 0.6 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.1 0.7 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 0.4 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.5 GO:0098982 GABA-ergic synapse(GO:0098982)
0.0 0.2 GO:0042583 chromaffin granule(GO:0042583)
0.0 0.4 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 1.4 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.2 GO:0008247 1-alkyl-2-acetylglycerophosphocholine esterase complex(GO:0008247)
0.0 0.5 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.2 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 2.0 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.8 GO:0097546 ciliary base(GO:0097546)
0.0 0.7 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 0.6 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.0 1.3 GO:0016605 PML body(GO:0016605)
0.0 0.8 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.2 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 1.9 GO:0022626 cytosolic ribosome(GO:0022626)
0.0 0.5 GO:0030286 dynein complex(GO:0030286)
0.0 1.3 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.1 GO:0043218 compact myelin(GO:0043218) Schmidt-Lanterman incisure(GO:0043220)
0.0 1.1 GO:0005861 troponin complex(GO:0005861)
0.0 0.3 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 0.5 GO:0032420 stereocilium(GO:0032420)
0.0 0.4 GO:0036038 MKS complex(GO:0036038)
0.0 0.2 GO:0016272 prefoldin complex(GO:0016272)
0.0 1.7 GO:0005930 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 0.2 GO:0097648 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor heterodimeric complex(GO:0038039) G-protein coupled receptor complex(GO:0097648)
0.0 0.3 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.5 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.9 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.3 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.6 GO:0031594 neuromuscular junction(GO:0031594)
0.0 1.0 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 1.2 GO:0005814 centriole(GO:0005814)
0.0 0.3 GO:0031209 SCAR complex(GO:0031209)
0.0 0.3 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.5 GO:0098978 glutamatergic synapse(GO:0098978)
0.0 0.7 GO:0016342 catenin complex(GO:0016342)
0.0 0.2 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.3 GO:0032039 integrator complex(GO:0032039)
0.0 0.2 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.5 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 0.3 GO:0005921 gap junction(GO:0005921)
0.0 0.1 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.5 GO:0031941 filamentous actin(GO:0031941)
0.0 0.1 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.2 GO:0043195 terminal bouton(GO:0043195)
0.0 0.6 GO:0032580 Golgi cisterna membrane(GO:0032580)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0070738 protein-glycine ligase activity(GO:0070735) tubulin-glycine ligase activity(GO:0070738)
0.4 3.4 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.3 1.4 GO:0008929 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
0.3 0.9 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.2 3.6 GO:0005504 fatty acid binding(GO:0005504)
0.2 0.6 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.2 1.1 GO:0008158 hedgehog receptor activity(GO:0008158)
0.2 0.5 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.1 0.6 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.1 0.6 GO:0004379 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379)
0.1 0.8 GO:0008502 melatonin receptor activity(GO:0008502)
0.1 0.5 GO:0044548 S100 protein binding(GO:0044548)
0.1 0.9 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.1 1.3 GO:0016936 galactoside binding(GO:0016936)
0.1 0.4 GO:0004377 GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity(GO:0004377)
0.1 0.4 GO:0047777 (3S)-citramalyl-CoA lyase activity(GO:0047777)
0.1 0.4 GO:0033961 cis-stilbene-oxide hydrolase activity(GO:0033961)
0.1 0.6 GO:0070412 R-SMAD binding(GO:0070412)
0.1 0.8 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.1 0.4 GO:0048407 platelet-derived growth factor-activated receptor activity(GO:0005017) platelet-derived growth factor binding(GO:0048407)
0.1 0.5 GO:0008184 phosphorylase activity(GO:0004645) glycogen phosphorylase activity(GO:0008184)
0.1 0.5 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.1 0.4 GO:0070513 death domain binding(GO:0070513)
0.1 0.7 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1 0.5 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 0.2 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.1 0.2 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.1 0.6 GO:0001130 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.1 0.7 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 0.5 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 0.9 GO:0031720 haptoglobin binding(GO:0031720)
0.1 0.4 GO:0004385 guanylate kinase activity(GO:0004385)
0.1 0.5 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.1 1.1 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.1 0.2 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.1 0.3 GO:0043295 glutathione binding(GO:0043295)
0.1 0.3 GO:0033842 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity(GO:0033842)
0.1 0.5 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.1 0.5 GO:0070698 type I activin receptor binding(GO:0070698)
0.1 0.9 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1 0.2 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.1 1.4 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 1.0 GO:0043236 laminin binding(GO:0043236)
0.1 0.7 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.1 0.2 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.1 0.3 GO:0003977 UDP-N-acetylglucosamine diphosphorylase activity(GO:0003977)
0.0 0.4 GO:0043515 kinetochore binding(GO:0043515)
0.0 2.0 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.4 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 1.0 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.8 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.7 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.3 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.4 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.0 1.2 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.3 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.7 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.6 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.4 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.0 1.3 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.4 GO:0000048 peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.0 0.2 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.0 0.4 GO:0008263 mismatch base pair DNA N-glycosylase activity(GO:0000700) pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263)
0.0 0.2 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.0 0.5 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.8 GO:0019894 kinesin binding(GO:0019894)
0.0 0.2 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.4 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.5 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.8 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.0 0.3 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062) collagen receptor activity(GO:0038064)
0.0 0.4 GO:0052812 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.0 0.1 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.0 0.1 GO:0000035 acyl binding(GO:0000035)
0.0 0.2 GO:0004362 glutathione-disulfide reductase activity(GO:0004362)
0.0 0.2 GO:0005542 folic acid binding(GO:0005542) ammonia-lyase activity(GO:0016841)
0.0 0.2 GO:0045735 nutrient reservoir activity(GO:0045735)
0.0 0.3 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.6 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.5 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.5 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.0 0.2 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.2 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.7 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.2 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 1.3 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.7 GO:0005343 organic acid:sodium symporter activity(GO:0005343)
0.0 2.0 GO:0003724 RNA helicase activity(GO:0003724)
0.0 0.3 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.1 GO:0052905 tRNA (guanine(9)-N(1))-methyltransferase activity(GO:0052905)
0.0 0.6 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 0.7 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.2 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.7 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 2.8 GO:0036459 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.1 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 0.8 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.1 GO:0048030 disaccharide binding(GO:0048030)
0.0 1.3 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.8 GO:0071949 FAD binding(GO:0071949)
0.0 0.2 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.6 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.1 GO:0048763 ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763)
0.0 0.1 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 0.4 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.1 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.4 GO:0009055 electron carrier activity(GO:0009055)
0.0 0.1 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 1.1 GO:0044389 ubiquitin-like protein ligase binding(GO:0044389)
0.0 0.2 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.2 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.0 0.2 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.1 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.1 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.3 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.3 GO:0016289 CoA hydrolase activity(GO:0016289)
0.0 0.6 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.7 GO:0005178 integrin binding(GO:0005178)
0.0 0.3 GO:0022829 wide pore channel activity(GO:0022829)
0.0 0.1 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.2 GO:0072542 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.0 0.1 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 1.0 GO:0045296 cadherin binding(GO:0045296)
0.0 0.3 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.1 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.2 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.2 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.8 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 1.5 GO:0015293 symporter activity(GO:0015293)
0.0 1.0 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.0 0.1 GO:0008503 benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.1 GO:0031769 glucagon receptor binding(GO:0031769)
0.0 0.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.4 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 3.8 PID E2F PATHWAY E2F transcription factor network
0.0 0.5 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 1.0 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.7 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 1.3 PID BMP PATHWAY BMP receptor signaling
0.0 1.0 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.5 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.5 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.2 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.4 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.6 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.6 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.7 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.3 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.4 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.3 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.1 1.1 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.1 0.6 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.1 1.5 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.1 0.7 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.1 0.5 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.6 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.3 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 1.3 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.4 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 2.0 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.6 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 1.0 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.3 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.5 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 1.3 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.8 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.1 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.4 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 0.4 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.7 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.4 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.5 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.2 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.9 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 1.9 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 1.0 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 1.7 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 1.6 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.3 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.9 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.1 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0 0.3 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 1.0 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.7 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.1 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.4 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.5 REACTOME PI3K AKT ACTIVATION Genes involved in PI3K/AKT activation
0.0 0.2 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.2 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.2 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.2 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 1.3 REACTOME MRNA SPLICING Genes involved in mRNA Splicing