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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for nr2c2

Z-value: 0.67

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Transcription factors associated with nr2c2

Gene Symbol Gene ID Gene Info
nr2c2
ENSDARG00000042477 nuclear receptor subfamily 2, group C, member 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nr2c2dr11_v1_chr8_+_53120278_53120278-0.135.9e-01Click!

Activity profile of nr2c2 motif

Sorted Z-values of nr2c2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_154556 4.68 ENSDART00000193153
zglp1
zinc finger, GATA-like protein 1
chr23_+_2740741 2.65 ENSDART00000134938
zgc:114123
zgc:114123
chr9_+_33216945 2.20 ENSDART00000134029
si:ch211-125e6.12
si:ch211-125e6.12
chr10_-_21362071 2.11 ENSDART00000125167
avd
avidin
chr4_-_858434 2.03 ENSDART00000006961
sobpb
sine oculis binding protein homolog (Drosophila) b
chr22_+_25184459 1.96 ENSDART00000105308
si:ch211-226h8.4
si:ch211-226h8.4
chr18_-_127558 1.72 ENSDART00000149556
trpm7
transient receptor potential cation channel, subfamily M, member 7
chr9_+_22782027 1.68 ENSDART00000090816
rif1
replication timing regulatory factor 1
chr22_+_25289360 1.67 ENSDART00000143782
si:ch211-154a22.8
si:ch211-154a22.8
chr19_-_27564458 1.61 ENSDART00000123155
si:dkeyp-46h3.6
si:dkeyp-46h3.6
chr18_-_158541 1.55 ENSDART00000188914
ENSDART00000191052
trpm7
transient receptor potential cation channel, subfamily M, member 7
chr23_+_30736895 1.52 ENSDART00000042944
asxl1
additional sex combs like transcriptional regulator 1
chr8_-_2529878 1.48 ENSDART00000056767
acaa2
acetyl-CoA acyltransferase 2
chr3_+_27770110 1.47 ENSDART00000017962
eci1
enoyl-CoA delta isomerase 1
chr19_-_27564980 1.46 ENSDART00000171967
si:dkeyp-46h3.8
si:dkeyp-46h3.8
chr10_+_1849874 1.46 ENSDART00000158897
ENSDART00000149956
apc
adenomatous polyposis coli
chr10_-_34916208 1.44 ENSDART00000187371
ccna1
cyclin A1
chr23_+_30730121 1.41 ENSDART00000134141
asxl1
additional sex combs like transcriptional regulator 1
chr10_+_15340768 1.40 ENSDART00000046274
ENSDART00000168909
trappc13
trafficking protein particle complex 13
chr2_-_57076687 1.32 ENSDART00000161523
slc25a42
solute carrier family 25, member 42
chr23_-_10696626 1.31 ENSDART00000177571
foxp1a
forkhead box P1a
chr3_-_34561624 1.30 ENSDART00000129313
sept9a
septin 9a
chr11_-_44999858 1.29 ENSDART00000167759
ENSDART00000126845
ldb1b
LIM-domain binding 1b
chr19_-_3056235 1.25 ENSDART00000137020
bop1
block of proliferation 1
chr18_+_27515640 1.24 ENSDART00000181593
tp53i11b
tumor protein p53 inducible protein 11b
chr5_+_22579975 1.24 ENSDART00000080877
tnfsf10l4
tumor necrosis factor (ligand) superfamily, member 10 like 4
chr3_+_7808459 1.23 ENSDART00000162374
hook2
hook microtubule-tethering protein 2
chr14_+_989733 1.18 ENSDART00000161487
ENSDART00000127317
si:ch73-308l14.2
si:ch73-308l14.2
chr23_-_44819100 1.14 ENSDART00000076373
st8sia7.1
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 7.1
chr21_-_9446747 1.14 ENSDART00000158790
ptpn13
protein tyrosine phosphatase, non-receptor type 13
chr18_+_30441740 1.11 ENSDART00000189074
gse1
Gse1 coiled-coil protein
chr25_-_25575717 1.11 ENSDART00000067138
hic1l
hypermethylated in cancer 1 like
chr19_-_874888 1.11 ENSDART00000007206
eomesa
eomesodermin homolog a
chr21_+_7605803 1.11 ENSDART00000121813
wdr41
WD repeat domain 41
chr17_+_24036791 1.10 ENSDART00000140767
b3gnt2b
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2b
chr21_+_1119046 1.10 ENSDART00000184678
CABZ01088049.1

chr1_+_24387659 1.09 ENSDART00000130356
qdprb2
quinoid dihydropteridine reductase b2
chr20_+_26943072 1.07 ENSDART00000153215
cdca4
cell division cycle associated 4
chr16_-_19568388 1.05 ENSDART00000141616
abcb5
ATP-binding cassette, sub-family B (MDR/TAP), member 5
chr14_+_32918172 1.00 ENSDART00000182867
lnx2b
ligand of numb-protein X 2b
chr7_-_24520866 1.00 ENSDART00000077039
faah2b
fatty acid amide hydrolase 2b
chr14_+_30413312 1.00 ENSDART00000186864
cnot7
CCR4-NOT transcription complex, subunit 7
chr18_+_8917766 0.99 ENSDART00000145226
si:ch211-233h19.2
si:ch211-233h19.2
chr9_+_8380728 0.98 ENSDART00000133501
si:ch1073-75o15.4
si:ch1073-75o15.4
chr8_+_15251448 0.97 ENSDART00000063717
zgc:171480
zgc:171480
chr18_-_12957451 0.95 ENSDART00000140403
srgap1a
SLIT-ROBO Rho GTPase activating protein 1a
chr22_-_24992532 0.92 ENSDART00000102751
si:dkey-179j5.5
si:dkey-179j5.5
chr6_+_40952031 0.92 ENSDART00000189219
patz1
POZ (BTB) and AT hook containing zinc finger 1
chr22_-_11833317 0.92 ENSDART00000125423
ENSDART00000000192
ptpn4b
protein tyrosine phosphatase, non-receptor type 4b
chr9_-_28990649 0.90 ENSDART00000078823
ptpn4a
protein tyrosine phosphatase, non-receptor type 4a
chr7_+_35193832 0.88 ENSDART00000189002
zdhhc1
zinc finger, DHHC-type containing 1
chr8_+_2530065 0.86 ENSDART00000063943
mrpl40
mitochondrial ribosomal protein L40
chr23_-_29394505 0.85 ENSDART00000017728
pgd
phosphogluconate dehydrogenase
chr25_-_25575241 0.84 ENSDART00000150636
hic1l
hypermethylated in cancer 1 like
chr12_-_33568174 0.84 ENSDART00000142329
tdrkh
tudor and KH domain containing
chr24_-_21172122 0.83 ENSDART00000154259
atp6v1ab
ATPase H+ transporting V1 subunit Ab
chr25_+_33256012 0.82 ENSDART00000059800
lactb
lactamase, beta
chr17_+_33418475 0.82 ENSDART00000169145
snap23.1
synaptosomal-associated protein 23.1
chr14_+_32918484 0.82 ENSDART00000105721
lnx2b
ligand of numb-protein X 2b
chr2_-_42558549 0.81 ENSDART00000025997
dip2cb
disco-interacting protein 2 homolog Cb
chr25_+_418932 0.79 ENSDART00000059193
prtgb
protogenin homolog b (Gallus gallus)
chr13_+_7241170 0.79 ENSDART00000109434
aifm2
apoptosis-inducing factor, mitochondrion-associated, 2
chr21_+_38089036 0.78 ENSDART00000147219
klf8
Kruppel-like factor 8
chr9_-_32300783 0.78 ENSDART00000078596
hspd1
heat shock 60 protein 1
chr13_+_30506781 0.77 ENSDART00000110884
zmiz1a
zinc finger, MIZ-type containing 1a
chr10_-_22797959 0.77 ENSDART00000183269
pcolcea
procollagen C-endopeptidase enhancer a
chr17_-_25303486 0.77 ENSDART00000162235
ppie
peptidylprolyl isomerase E (cyclophilin E)
chr24_+_39137001 0.77 ENSDART00000181086
ENSDART00000183724
ENSDART00000193466
tbc1d24
TBC1 domain family, member 24
chr4_-_75172216 0.77 ENSDART00000127522
naa40
N(alpha)-acetyltransferase 40, NatD catalytic subunit, homolog (S. cerevisiae)
chr18_+_1615 0.76 ENSDART00000082450
homer2
homer scaffolding protein 2
chr23_+_2914577 0.76 ENSDART00000184897
DHX35
zgc:158828
chr15_+_34963316 0.75 ENSDART00000153840
si:ch73-95l15.5
si:ch73-95l15.5
chr16_-_25233515 0.75 ENSDART00000058943
zgc:110182
zgc:110182
chr18_-_34549721 0.75 ENSDART00000137101
ENSDART00000021880
ssr3
signal sequence receptor, gamma
chr21_+_15883546 0.73 ENSDART00000186325
fam169ab
family with sequence similarity 169, member Ab
chr18_+_25546227 0.73 ENSDART00000085824
pex11a
peroxisomal biogenesis factor 11 alpha
chr9_-_32300611 0.73 ENSDART00000127938
hspd1
heat shock 60 protein 1
chr16_-_19568795 0.72 ENSDART00000185141
abcb5
ATP-binding cassette, sub-family B (MDR/TAP), member 5
chr19_-_20099394 0.71 ENSDART00000126173
mpp6b
membrane protein, palmitoylated 6b (MAGUK p55 subfamily member 6)
chr9_+_21151138 0.69 ENSDART00000133903
hao2
hydroxyacid oxidase 2 (long chain)
chr8_+_10862353 0.67 ENSDART00000140717
brpf3b
bromodomain and PHD finger containing, 3b
chr20_+_36806398 0.67 ENSDART00000153317
abracl
ABRA C-terminal like
chr1_+_1712140 0.66 ENSDART00000081047
atp1a1a.1
ATPase Na+/K+ transporting subunit alpha 1a, tandem duplicate 1
chr12_+_19138452 0.66 ENSDART00000141346
ENSDART00000066397
phf5a
PHD finger protein 5A
chr1_-_26664840 0.65 ENSDART00000102500
anp32b
acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
chr25_+_22017182 0.65 ENSDART00000156517
si:dkey-217l24.1
si:dkey-217l24.1
chr12_+_48972915 0.65 ENSDART00000170695
lrit1b
leucine-rich repeat, immunoglobulin-like and transmembrane domains 1b
chr24_-_23716097 0.65 ENSDART00000084954
ENSDART00000129028
pign
phosphatidylinositol glycan anchor biosynthesis, class N
chr25_+_25766033 0.65 ENSDART00000103638
ENSDART00000039952
idh3a
isocitrate dehydrogenase 3 (NAD+) alpha
chr10_+_11265387 0.65 ENSDART00000038888
hsdl2
hydroxysteroid dehydrogenase like 2
chr20_-_1635922 0.65 ENSDART00000181502
CR846082.1

chr13_-_36566260 0.64 ENSDART00000030133
synj2bp
synaptojanin 2 binding protein
chr13_-_35808904 0.64 ENSDART00000171667
map3k4
mitogen-activated protein kinase kinase kinase 4
chr20_+_6535438 0.64 ENSDART00000145763
si:ch211-191a24.4
si:ch211-191a24.4
chr13_-_25199260 0.63 ENSDART00000057605
adka
adenosine kinase a
chr7_+_25000060 0.63 ENSDART00000039265
ENSDART00000141814
naa40
N(alpha)-acetyltransferase 40, NatD catalytic subunit, homolog (S. cerevisiae)
chr20_-_51656512 0.63 ENSDART00000129965
LO018154.1

chr13_+_46944607 0.63 ENSDART00000187352
fbxo5
F-box protein 5
chr2_-_22660232 0.62 ENSDART00000174742
thap4
THAP domain containing 4
chr15_+_47618221 0.62 ENSDART00000168722
paf1
PAF1 homolog, Paf1/RNA polymerase II complex component
chr16_-_27138478 0.61 ENSDART00000147438
tmem245
transmembrane protein 245
chr3_-_18805225 0.61 ENSDART00000133471
ENSDART00000131758
msrb1a
methionine sulfoxide reductase B1a
chr13_-_42724645 0.61 ENSDART00000046066
capn1a
calpain 1, (mu/I) large subunit a
chr3_-_36419641 0.61 ENSDART00000173545
cog1
component of oligomeric golgi complex 1
chr6_-_41138854 0.60 ENSDART00000128723
ENSDART00000151055
ENSDART00000132484
slc6a22.1
solute carrier family 6 member 22, tandem duplicate 1
chr2_+_58377395 0.60 ENSDART00000193511
vapal
VAMP (vesicle-associated membrane protein)-associated protein A, like
chr12_+_48681601 0.60 ENSDART00000187831
uros
uroporphyrinogen III synthase
chr8_+_50742975 0.60 ENSDART00000155664
ENSDART00000160612
si:ch73-6l19.2
si:ch73-6l19.2
chr22_-_7050 0.60 ENSDART00000127829
atad3
ATPase family, AAA domain containing 3
chr2_-_22659450 0.59 ENSDART00000115025
thap4
THAP domain containing 4
chr1_+_54737353 0.58 ENSDART00000130675
ENSDART00000162075
pi4k2a
phosphatidylinositol 4-kinase type 2 alpha
chr21_+_31253048 0.57 ENSDART00000178521
ENSDART00000132317
ENSDART00000040190
asl
argininosuccinate lyase
chr18_-_16916840 0.56 ENSDART00000100105
swap70b
switching B cell complex subunit SWAP70b
chr20_+_27093042 0.56 ENSDART00000024595
ubr7
ubiquitin protein ligase E3 component n-recognin 7
chr9_-_25255490 0.55 ENSDART00000141502
htr2aa
5-hydroxytryptamine (serotonin) receptor 2A, genome duplicate a
chr23_+_25172682 0.55 ENSDART00000191197
ENSDART00000183497
si:dkey-151g10.3
si:dkey-151g10.3
chr3_+_31680592 0.54 ENSDART00000172456
mylk5
myosin, light chain kinase 5
chr7_+_48297842 0.54 ENSDART00000052123
slc25a44b
solute carrier family 25, member 44 b
chr18_-_49283058 0.54 ENSDART00000076554
si:zfos-464b6.2
si:zfos-464b6.2
chr5_+_43470544 0.53 ENSDART00000111587
rhobtb2a
Rho-related BTB domain containing 2a
chr15_-_1843831 0.53 ENSDART00000156718
ENSDART00000154175
taf15
TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr10_-_105100 0.53 ENSDART00000145716
ttc3
tetratricopeptide repeat domain 3
chr17_-_49407091 0.52 ENSDART00000021950
mthfd1b
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1b
chr20_-_21994901 0.52 ENSDART00000004984
daam1b
dishevelled associated activator of morphogenesis 1b
chr3_+_40289418 0.52 ENSDART00000017304
cpsf4
cleavage and polyadenylation specific factor 4
chr8_+_36570791 0.52 ENSDART00000145566
ENSDART00000180527
pold2
polymerase (DNA directed), delta 2, regulatory subunit
chr15_-_30857350 0.51 ENSDART00000138988
akap1b
A kinase (PRKA) anchor protein 1b
chr7_+_47243564 0.51 ENSDART00000098942
ENSDART00000162237
znf507
zinc finger protein 507
chr14_+_30413758 0.51 ENSDART00000092953
cnot7
CCR4-NOT transcription complex, subunit 7
chr24_-_7587401 0.50 ENSDART00000093163
galnt11
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11)
chr13_-_33114933 0.50 ENSDART00000140543
ENSDART00000075953
zfyve26
zinc finger, FYVE domain containing 26
chr11_-_27778831 0.50 ENSDART00000023823
cass4
Cas scaffolding protein family member 4
chr12_-_35787801 0.49 ENSDART00000171682
aatkb
apoptosis-associated tyrosine kinase b
chr21_-_1640547 0.49 ENSDART00000151041
zgc:152948
zgc:152948
chr12_-_850457 0.49 ENSDART00000022688
tob1b
transducer of ERBB2, 1b
chr25_-_20049449 0.49 ENSDART00000104315
zgc:136858
zgc:136858
chr7_+_22718251 0.49 ENSDART00000027718
ENSDART00000143341
fxr2
fragile X mental retardation, autosomal homolog 2
chr6_-_28117995 0.49 ENSDART00000147253
si:ch73-194h10.3
si:ch73-194h10.3
chr4_-_16833518 0.48 ENSDART00000179867
ldhba
lactate dehydrogenase Ba
chr18_+_35229115 0.48 ENSDART00000129624
ENSDART00000184596
tbrg1
transforming growth factor beta regulator 1
chr10_-_38456382 0.48 ENSDART00000182129
gdpd5a
glycerophosphodiester phosphodiesterase domain containing 5a
chr8_+_40275830 0.47 ENSDART00000164414
orai1a
ORAI calcium release-activated calcium modulator 1a
chr20_+_6535176 0.47 ENSDART00000054652
si:ch211-191a24.4
si:ch211-191a24.4
chr5_-_23705828 0.47 ENSDART00000189419
gbgt1l1
globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 1
chr25_-_35113891 0.47 ENSDART00000190724
zgc:165555
zgc:165555
chr21_-_21515466 0.46 ENSDART00000147593
nectin3b
nectin cell adhesion molecule 3b
chr5_+_35786141 0.46 ENSDART00000022043
ENSDART00000127383
stard8
StAR-related lipid transfer (START) domain containing 8
chr20_+_47953047 0.46 ENSDART00000079734
hadhaa
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha a
chr10_+_17235370 0.46 ENSDART00000038780
sppl3
signal peptide peptidase 3
chr14_+_1719367 0.45 ENSDART00000157696
trpc7b
transient receptor potential cation channel, subfamily C, member 7b
chr1_-_44581937 0.45 ENSDART00000009858
tmx2b
thioredoxin-related transmembrane protein 2b
chr3_+_50201240 0.45 ENSDART00000156347
epn3a
epsin 3a
chr19_+_26424734 0.44 ENSDART00000187402
npr1a
natriuretic peptide receptor 1a
chr15_-_6946286 0.44 ENSDART00000019330
ech1
enoyl CoA hydratase 1, peroxisomal
chr19_-_24136233 0.44 ENSDART00000143365
thap7
THAP domain containing 7
chr22_-_14262115 0.44 ENSDART00000168264
si:ch211-246m6.5
si:ch211-246m6.5
chr5_-_67267678 0.44 ENSDART00000156795
ENSDART00000125781
ENSDART00000125874
zcchc8
zinc finger, CCHC domain containing 8
chr14_-_6286966 0.44 ENSDART00000168174
elp1
elongator complex protein 1
chr1_-_51720633 0.43 ENSDART00000045894
rnaseh2a
ribonuclease H2, subunit A
chr14_+_22498757 0.43 ENSDART00000021657
smyd5
SMYD family member 5
chr3_+_301479 0.43 ENSDART00000165169
CABZ01075611.1

chr7_+_24520518 0.43 ENSDART00000173604
btr09
bloodthirsty-related gene family, member 9
chr2_+_35880600 0.43 ENSDART00000004277
lamc1
laminin, gamma 1
chr8_+_36570508 0.42 ENSDART00000145868
pold2
polymerase (DNA directed), delta 2, regulatory subunit
chr13_-_24260609 0.42 ENSDART00000138747
urb2
URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
chr3_+_34121156 0.42 ENSDART00000174929
aldh3b1
aldehyde dehydrogenase 3 family, member B1
chr5_-_19444930 0.40 ENSDART00000136259
ENSDART00000188499
kctd10
potassium channel tetramerization domain containing 10
chr25_+_14694876 0.40 ENSDART00000050478
ENSDART00000188093
mpped2
metallophosphoesterase domain containing 2b
chr5_-_30516646 0.40 ENSDART00000014666
arcn1a
archain 1a
chr7_-_40578733 0.40 ENSDART00000173926
ENSDART00000010035
dnajb6b
DnaJ (Hsp40) homolog, subfamily B, member 6b
chr14_-_49992709 0.40 ENSDART00000159988
fam193b
family with sequence similarity 193, member B
chr3_+_12755535 0.39 ENSDART00000161286
cyp2k17
cytochrome P450, family 2, subfamily K, polypeptide17
chr10_+_589501 0.39 ENSDART00000188415
LO018557.1

chr2_+_6067371 0.38 ENSDART00000053868
ENSDART00000145244
aldh9a1b
aldehyde dehydrogenase 9 family, member A1b
chr7_-_36113098 0.38 ENSDART00000064913
fto
fat mass and obesity associated
chr20_-_874807 0.38 ENSDART00000020506
snx14
sorting nexin 14
chr23_+_25172976 0.37 ENSDART00000140789
si:dkey-151g10.3
si:dkey-151g10.3
chr13_-_41546779 0.37 ENSDART00000163331
pcdh15a
protocadherin-related 15a
chr21_+_41743493 0.36 ENSDART00000192669
ppp2r2bb
protein phosphatase 2, regulatory subunit B, beta b
chr3_+_1179601 0.36 ENSDART00000173378
triobpb
TRIO and F-actin binding protein b
chr24_-_11446156 0.35 ENSDART00000143921
ENSDART00000066778
acad11
acyl-CoA dehydrogenase family, member 11
chr3_+_3810919 0.35 ENSDART00000056035
FQ311927.1

chr17_-_27200634 0.34 ENSDART00000185332
asap3
ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
chr1_-_44314 0.34 ENSDART00000160050
tmem39a
transmembrane protein 39A
chr7_+_31374383 0.34 ENSDART00000085505
ctdspl2b
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2b
chr25_-_21085661 0.34 ENSDART00000099355
prr5a
proline rich 5a (renal)
chr13_+_5013572 0.34 ENSDART00000162425
psap
prosaposin
chr2_-_37744951 0.33 ENSDART00000144807
myo9b
myosin IXb
chr12_+_1286642 0.33 ENSDART00000157467
pemt
phosphatidylethanolamine N-methyltransferase
chr17_+_654759 0.33 ENSDART00000193703
CABZ01079748.1

chr11_-_31234584 0.33 ENSDART00000170700
nacc1b
nucleus accumbens associated 1, BEN and BTB (POZ) domain containing b
chr15_-_28793163 0.33 ENSDART00000182294
cd3eap
CD3e molecule, epsilon associated protein
chr20_+_26905158 0.33 ENSDART00000138249
rwdd2b
RWD domain containing 2B
chr25_+_12012 0.32 ENSDART00000170348
cntn1a
contactin 1a
chr3_-_5829501 0.32 ENSDART00000091017
pkn1b
protein kinase N1b
chr11_+_11751006 0.32 ENSDART00000180372
ENSDART00000081018
jupa
junction plakoglobin a
chr17_-_22137199 0.32 ENSDART00000089689
mrps5
mitochondrial ribosomal protein S5
chr2_-_8102169 0.31 ENSDART00000131955
pls1
plastin 1 (I isoform)
chr17_-_17759138 0.31 ENSDART00000157128
ENSDART00000123845
adck1
aarF domain containing kinase 1
chr23_-_46126444 0.30 ENSDART00000030004
CABZ01071903.1

Network of associatons between targets according to the STRING database.

First level regulatory network of nr2c2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.3 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.6 1.8 GO:0046689 response to mercury ion(GO:0046689) detoxification of mercury ion(GO:0050787)
0.4 1.5 GO:0045041 positive regulation of interleukin-6 production(GO:0032755) protein import into mitochondrial intermembrane space(GO:0045041)
0.4 1.1 GO:0055109 invagination involved in gastrulation with mouth forming second(GO:0055109) morphogenesis of an epithelial fold(GO:0060571)
0.4 1.5 GO:0090244 endodermal digestive tract morphogenesis(GO:0061031) Wnt signaling pathway involved in somitogenesis(GO:0090244) negative regulation of canonical Wnt signaling pathway involved in heart development(GO:1905067)
0.3 2.7 GO:0033206 meiotic cytokinesis(GO:0033206) polar body extrusion after meiotic divisions(GO:0040038)
0.2 0.6 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.2 0.3 GO:0003308 negative regulation of Wnt signaling pathway involved in heart development(GO:0003308)
0.2 0.6 GO:0051444 negative regulation of ligase activity(GO:0051352) negative regulation of ubiquitin-protein transferase activity(GO:0051444) negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.1 1.5 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998)
0.1 0.4 GO:0002926 tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridine biosynthesis.(GO:0002926)
0.1 0.6 GO:0006526 arginine biosynthetic process(GO:0006526)
0.1 1.5 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.1 0.4 GO:0042245 RNA repair(GO:0042245)
0.1 1.8 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.1 0.7 GO:0016559 peroxisome fission(GO:0016559)
0.1 1.1 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.1 0.6 GO:0044209 AMP salvage(GO:0044209)
0.1 0.4 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.1 0.3 GO:1905048 regulation of metallopeptidase activity(GO:1905048)
0.1 0.4 GO:0051645 Golgi localization(GO:0051645)
0.1 0.5 GO:0090527 actin filament reorganization(GO:0090527)
0.1 0.5 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.1 1.1 GO:0021684 cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.1 0.3 GO:0019408 dolichol biosynthetic process(GO:0019408)
0.1 0.8 GO:0021628 olfactory nerve development(GO:0021553) olfactory nerve morphogenesis(GO:0021627) olfactory nerve formation(GO:0021628)
0.1 0.7 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.1 0.6 GO:0048714 positive regulation of glial cell differentiation(GO:0045687) positive regulation of oligodendrocyte differentiation(GO:0048714)
0.1 4.5 GO:0048599 oocyte development(GO:0048599)
0.1 0.7 GO:0006102 isocitrate metabolic process(GO:0006102)
0.1 0.4 GO:1903573 negative regulation of response to endoplasmic reticulum stress(GO:1903573)
0.1 1.1 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.1 0.2 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
0.1 0.4 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.1 0.8 GO:0006098 pentose-phosphate shunt(GO:0006098)
0.1 1.2 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.1 0.3 GO:0046551 retinal cone cell fate determination(GO:0042671) eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate determination(GO:0043703) retinal cone cell fate commitment(GO:0046551) photoreceptor cell fate commitment(GO:0046552) camera-type eye photoreceptor cell fate commitment(GO:0060220)
0.1 1.9 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.1 0.2 GO:0070914 UV-damage excision repair(GO:0070914)
0.1 0.9 GO:0006271 DNA strand elongation involved in DNA replication(GO:0006271)
0.1 0.8 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.1 0.3 GO:0051972 regulation of telomerase activity(GO:0051972)
0.1 0.5 GO:0098787 mRNA cleavage involved in mRNA processing(GO:0098787) pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.1 0.4 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.1 0.2 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.1 0.5 GO:0035188 hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.1 1.1 GO:0006491 N-glycan processing(GO:0006491)
0.1 1.8 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.1 0.5 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.7 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.0 0.5 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.4 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.0 0.7 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.4 GO:1901998 toxin transport(GO:1901998)
0.0 0.3 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.0 0.1 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.0 0.4 GO:0045638 negative regulation of myeloid cell differentiation(GO:0045638)
0.0 0.9 GO:0051928 positive regulation of calcium ion transport(GO:0051928)
0.0 0.4 GO:0021680 cerebellar Purkinje cell layer development(GO:0021680)
0.0 0.6 GO:0046501 protoporphyrinogen IX biosynthetic process(GO:0006782) protoporphyrinogen IX metabolic process(GO:0046501)
0.0 0.4 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.4 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.5 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.0 0.2 GO:0016139 glycoside metabolic process(GO:0016137) glycoside catabolic process(GO:0016139)
0.0 0.2 GO:0043589 skin morphogenesis(GO:0043589) mesenchymal cell migration(GO:0090497)
0.0 0.5 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.9 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.5 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.0 0.2 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.3 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.2 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.0 0.8 GO:0008637 apoptotic mitochondrial changes(GO:0008637)
0.0 0.2 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.0 1.4 GO:1904029 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.0 0.6 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 0.6 GO:0007032 endosome organization(GO:0007032)
0.0 0.5 GO:0030259 lipid glycosylation(GO:0030259)
0.0 0.8 GO:0016082 synaptic vesicle priming(GO:0016082)
0.0 0.8 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 1.7 GO:0032200 telomere maintenance(GO:0000723) telomere organization(GO:0032200)
0.0 1.1 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.9 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.8 GO:0007006 mitochondrial membrane organization(GO:0007006)
0.0 0.4 GO:0060038 cardiac muscle cell proliferation(GO:0060038)
0.0 0.1 GO:0099560 synaptic membrane adhesion(GO:0099560)
0.0 0.3 GO:0051639 actin filament network formation(GO:0051639)
0.0 1.2 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 0.6 GO:0051209 release of sequestered calcium ion into cytosol(GO:0051209)
0.0 0.5 GO:0032784 regulation of DNA-templated transcription, elongation(GO:0032784)
0.0 0.3 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.0 0.2 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.0 0.2 GO:0031295 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0 0.5 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.1 GO:1990504 dense core granule exocytosis(GO:1990504)
0.0 0.0 GO:0070589 cell wall biogenesis(GO:0042546) cell wall macromolecule biosynthetic process(GO:0044038) cellular component macromolecule biosynthetic process(GO:0070589)
0.0 0.6 GO:0097120 receptor localization to synapse(GO:0097120)
0.0 0.5 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 1.3 GO:0061640 cytoskeleton-dependent cytokinesis(GO:0061640)
0.0 0.4 GO:0043491 protein kinase B signaling(GO:0043491)
0.0 0.3 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.5 GO:0043652 engulfment of apoptotic cell(GO:0043652)
0.0 0.1 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 1.0 GO:0030336 negative regulation of cell migration(GO:0030336)
0.0 0.1 GO:0098920 endocannabinoid signaling pathway(GO:0071926) retrograde trans-synaptic signaling by lipid(GO:0098920) retrograde trans-synaptic signaling by endocannabinoid(GO:0098921)
0.0 0.4 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
0.0 1.3 GO:0010506 regulation of autophagy(GO:0010506)
0.0 0.2 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.0 0.1 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.1 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 0.5 GO:2001022 positive regulation of response to DNA damage stimulus(GO:2001022)
0.0 0.1 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.8 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.0 0.3 GO:0045879 negative regulation of smoothened signaling pathway(GO:0045879)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)
0.5 1.4 GO:1990072 TRAPPIII protein complex(GO:1990072)
0.4 2.9 GO:0035517 PR-DUB complex(GO:0035517)
0.4 1.2 GO:0070545 PeBoW complex(GO:0070545)
0.2 1.5 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.2 0.9 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.2 0.6 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.1 0.5 GO:0044326 dendritic spine neck(GO:0044326) dendritic filopodium(GO:1902737)
0.1 0.5 GO:0098553 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.1 0.4 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.1 0.3 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.1 0.7 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.1 0.2 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.1 0.3 GO:1990909 Wnt signalosome(GO:1990909)
0.1 0.3 GO:1904423 dehydrodolichyl diphosphate synthase complex(GO:1904423)
0.1 0.3 GO:0042584 chromaffin granule membrane(GO:0042584)
0.1 0.2 GO:0044609 DBIRD complex(GO:0044609)
0.1 2.0 GO:0000781 chromosome, telomeric region(GO:0000781)
0.0 0.8 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.2 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.6 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.2 GO:1990131 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.6 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.4 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.7 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.3 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 1.3 GO:0005940 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.7 GO:0005689 U2 snRNP(GO:0005686) U12-type spliceosomal complex(GO:0005689)
0.0 0.6 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.2 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 1.1 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.5 GO:0032420 stereocilium(GO:0032420)
0.0 0.5 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.1 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.0 0.7 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.1 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.3 GO:0030057 desmosome(GO:0030057)
0.0 0.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.3 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.1 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 0.3 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.4 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.3 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 3.2 GO:0030659 cytoplasmic vesicle membrane(GO:0030659)
0.0 0.5 GO:0030496 midbody(GO:0030496)
0.0 0.7 GO:0032432 actin filament bundle(GO:0032432)
0.0 0.1 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.8 GO:0031201 SNARE complex(GO:0031201)
0.0 1.1 GO:0000786 nucleosome(GO:0000786)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.9 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.5 1.5 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.4 1.3 GO:0080122 coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.4 2.1 GO:0009374 biotin binding(GO:0009374)
0.3 1.4 GO:0043998 H2A histone acetyltransferase activity(GO:0043998)
0.3 1.1 GO:0004155 6,7-dihydropteridine reductase activity(GO:0004155) NADH binding(GO:0070404)
0.2 1.9 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.2 3.3 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.2 1.3 GO:0030274 LIM domain binding(GO:0030274)
0.2 0.7 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.2 0.6 GO:0033745 L-methionine-(R)-S-oxide reductase activity(GO:0033745)
0.2 0.6 GO:0033149 FFAT motif binding(GO:0033149)
0.1 1.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 0.6 GO:0016842 amidine-lyase activity(GO:0016842)
0.1 0.7 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.1 0.4 GO:0043878 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity(GO:0043878)
0.1 0.6 GO:0004001 adenosine kinase activity(GO:0004001)
0.1 1.5 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 0.4 GO:1990931 oxidative DNA demethylase activity(GO:0035516) DNA-N1-methyladenine dioxygenase activity(GO:0043734) RNA N6-methyladenosine dioxygenase activity(GO:1990931)
0.1 1.1 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.1 0.6 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 1.1 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.1 0.2 GO:0004557 alpha-galactosidase activity(GO:0004557)
0.1 0.8 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 0.5 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.1 0.4 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.1 0.3 GO:0045547 dehydrodolichyl diphosphate synthase activity(GO:0045547)
0.1 0.3 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.1 0.5 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.1 0.7 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1 0.3 GO:0017020 myosin phosphatase regulator activity(GO:0017020)
0.1 0.4 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.1 0.2 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.1 0.3 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.1 0.5 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 0.4 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.1 0.8 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.7 GO:0043994 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.0 0.5 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0 0.6 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.3 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0 0.3 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.5 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.9 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 3.6 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 1.5 GO:0051087 chaperone binding(GO:0051087)
0.0 1.3 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.5 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.8 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.8 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.3 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 9.0 GO:0030246 carbohydrate binding(GO:0030246)
0.0 0.7 GO:0010181 FMN binding(GO:0010181)
0.0 1.5 GO:0008013 beta-catenin binding(GO:0008013)
0.0 1.2 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.3 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.0 0.9 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.2 GO:0051920 peroxiredoxin activity(GO:0051920)
0.0 0.5 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.8 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 1.4 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.9 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.1 GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor(GO:0016653)
0.0 0.4 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 1.2 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.0 0.5 GO:0045182 translation regulator activity(GO:0045182)
0.0 0.7 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.0 0.3 GO:0004698 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.0 1.8 GO:0016820 hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances(GO:0016820) ATPase activity, coupled to transmembrane movement of substances(GO:0042626) ATPase activity, coupled to movement of substances(GO:0043492)
0.0 0.1 GO:0016415 octanoyltransferase activity(GO:0016415)
0.0 0.8 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.4 GO:0015036 disulfide oxidoreductase activity(GO:0015036)
0.0 0.0 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.5 GO:0005347 ATP transmembrane transporter activity(GO:0005347)
0.0 2.0 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.0 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.1 1.4 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 1.7 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 1.1 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.4 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.6 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.4 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.8 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.6 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.3 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 0.9 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.2 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.3 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 1.5 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.1 1.5 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 1.4 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 0.9 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.1 1.8 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.3 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.7 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.6 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.7 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.6 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 1.7 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.6 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.3 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.3 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.3 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.1 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.2 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.3 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 0.5 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.2 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.3 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants