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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for nr2e3

Z-value: 1.36

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Transcription factors associated with nr2e3

Gene Symbol Gene ID Gene Info
nr2e3
ENSDARG00000045904 nuclear receptor subfamily 2, group E, member 3
nr2e3
ENSDARG00000113178 nuclear receptor subfamily 2, group E, member 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nr2e3dr11_v1_chr25_+_22274642_22274642-0.904.1e-07Click!

Activity profile of nr2e3 motif

Sorted Z-values of nr2e3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_27550768 3.94 ENSDART00000142313
si:dkeyp-46h3.8
si:dkeyp-46h3.8
chr21_-_30293224 3.60 ENSDART00000101051
slbp2
stem-loop binding protein 2
chr11_-_3494964 3.29 ENSDART00000162369
acap3b
ArfGAP with coiled-coil, ankyrin repeat and PH domains 3b
chr12_+_30789611 3.24 ENSDART00000181501
aldh18a1
aldehyde dehydrogenase 18 family, member A1
chr19_-_27564980 3.23 ENSDART00000171967
si:dkeyp-46h3.8
si:dkeyp-46h3.8
chr23_+_2740741 3.20 ENSDART00000134938
zgc:114123
zgc:114123
chr17_-_2596125 3.13 ENSDART00000175740
zp3.2
zona pellucida glycoprotein 3, tandem duplicate 2
chr24_-_10014512 3.01 ENSDART00000124341
ENSDART00000191630
zgc:171474
zgc:171474
chr13_-_6252498 2.82 ENSDART00000115157
tuba4l
tubulin, alpha 4 like
chr25_+_22319940 2.77 ENSDART00000154065
ENSDART00000153492
ENSDART00000024866
ENSDART00000154376
cyp11a1
cytochrome P450, family 11, subfamily A, polypeptide 1
chr10_+_3145707 2.76 ENSDART00000160046
hic2
hypermethylated in cancer 2
chr15_+_38299385 2.76 ENSDART00000142403
si:dkey-24p1.6
si:dkey-24p1.6
chr19_-_27564458 2.71 ENSDART00000123155
si:dkeyp-46h3.6
si:dkeyp-46h3.6
chr17_-_2578026 2.69 ENSDART00000065821
zp3.2
zona pellucida glycoprotein 3, tandem duplicate 2
chr20_+_33987465 2.69 ENSDART00000061751
zp3a.2
zona pellucida glycoprotein 3a, tandem duplicate 2
chr20_-_29498178 2.67 ENSDART00000152986
ENSDART00000027851
ENSDART00000152954
rrm2
ribonucleotide reductase M2 polypeptide
chr22_-_17652914 2.59 ENSDART00000138483
si:ch73-243b8.4
si:ch73-243b8.4
chr15_+_38299563 2.53 ENSDART00000099375
si:dkey-24p1.6
si:dkey-24p1.6
chr9_-_34269066 2.49 ENSDART00000059955
ildr1b
immunoglobulin-like domain containing receptor 1b
chr9_-_8314028 2.47 ENSDART00000102739
si:ch211-145c1.1
si:ch211-145c1.1
chr5_+_57924611 2.45 ENSDART00000050949
btg4
B-cell translocation gene 4
chr23_+_27756984 2.44 ENSDART00000137103
kmt2d
lysine (K)-specific methyltransferase 2D
chr20_-_44576949 2.33 ENSDART00000148639
ubxn2a
UBX domain protein 2A
chr9_+_33216945 2.33 ENSDART00000134029
si:ch211-125e6.12
si:ch211-125e6.12
chr12_+_13344896 2.29 ENSDART00000089017
rnasen
ribonuclease type III, nuclear
chr22_-_17652112 2.25 ENSDART00000189205
hmha1b
histocompatibility (minor) HA-1 b
chr21_-_21178410 2.24 ENSDART00000185277
ENSDART00000141341
ENSDART00000145872
ENSDART00000079678
ftsj1
FtsJ RNA methyltransferase homolog 1
chr23_-_22523303 2.23 ENSDART00000079019
spsb1
splA/ryanodine receptor domain and SOCS box containing 1
chr3_-_47235997 2.19 ENSDART00000047071
tmed1a
transmembrane p24 trafficking protein 1a
chr21_+_4116437 2.18 ENSDART00000167791
ENSDART00000123759
rapgef1b
Rap guanine nucleotide exchange factor (GEF) 1b
chr20_+_33991801 2.16 ENSDART00000061744
zp3a.1
zona pellucida glycoprotein 3a, tandem duplicate 1
chr24_-_5691956 2.12 ENSDART00000189112
dia1b
deleted in autism 1b
chr4_-_77114795 2.10 ENSDART00000144849
CU467646.2

chr14_+_30328567 2.10 ENSDART00000105889
mtus1a
microtubule associated tumor suppressor 1a
chr14_+_21722235 2.10 ENSDART00000183667
stx3a
syntaxin 3A
chr3_+_51563695 2.09 ENSDART00000008607
ttyh2l
tweety homolog 2, like
chr4_-_1757460 2.08 ENSDART00000144074
tm7sf3
transmembrane 7 superfamily member 3
chr19_-_47570672 2.07 ENSDART00000112155
rrm2
ribonucleotide reductase M2 polypeptide
chr19_+_42231431 1.92 ENSDART00000102698
jtb
jumping translocation breakpoint
chr17_+_5931530 1.91 ENSDART00000168326
ENSDART00000189790
znf513b
zinc finger protein 513b
chr12_-_25887864 1.90 ENSDART00000152983
si:dkey-193p11.2
si:dkey-193p11.2
chr14_+_22129096 1.90 ENSDART00000132514
ccng1
cyclin G1
chr21_-_37027252 1.89 ENSDART00000076483
zgc:77151
zgc:77151
chr5_+_25733774 1.88 ENSDART00000137088
ENSDART00000098467
abhd17b
abhydrolase domain containing 17B
chr6_+_32338334 1.88 ENSDART00000065149
dock7
dedicator of cytokinesis 7
chr10_+_15255012 1.88 ENSDART00000023766
vldlr
very low density lipoprotein receptor
chr5_+_37747128 1.87 ENSDART00000148795
dpf2
D4, zinc and double PHD fingers family 2
chr10_+_15255198 1.86 ENSDART00000139047
ENSDART00000172107
ENSDART00000183413
ENSDART00000185314
vldlr
very low density lipoprotein receptor
chr10_+_3153973 1.86 ENSDART00000183223
hic2
hypermethylated in cancer 2
chr5_-_20135679 1.86 ENSDART00000079402
usp30
ubiquitin specific peptidase 30
chr21_+_15723069 1.85 ENSDART00000149126
ENSDART00000130628
p2rx4a
purinergic receptor P2X, ligand-gated ion channel, 4a
chr13_-_24717365 1.84 ENSDART00000137934
ENSDART00000003922
erlin1
ER lipid raft associated 1
chr24_+_15020402 1.83 ENSDART00000148102
dok6
docking protein 6
chr1_+_59314675 1.80 ENSDART00000161872
ENSDART00000160658
ENSDART00000169792
ENSDART00000160735
parn
poly(A)-specific ribonuclease (deadenylation nuclease)
chr5_-_56964547 1.78 ENSDART00000074400
tia1
TIA1 cytotoxic granule-associated RNA binding protein
chr19_+_4968947 1.76 ENSDART00000003634
ENSDART00000134808
stard3
StAR-related lipid transfer (START) domain containing 3
chr10_+_16911951 1.74 ENSDART00000164933
UNC13B (1 of many)
unc-13 homolog B
chr1_+_2431956 1.73 ENSDART00000183832
farp1
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr8_+_26396552 1.72 ENSDART00000087151
amt
aminomethyltransferase
chr7_-_18554603 1.71 ENSDART00000108938
msantd1
Myb/SANT-like DNA-binding domain containing 1
chr24_-_21090447 1.69 ENSDART00000136507
ENSDART00000140786
ENSDART00000184841
qtrt2
queuine tRNA-ribosyltransferase accessory subunit 2
chr18_+_50880096 1.69 ENSDART00000169782
si:ch1073-450f2.1
si:ch1073-450f2.1
chr8_-_25771474 1.68 ENSDART00000193883
suv39h1b
suppressor of variegation 3-9 homolog 1b
chr3_-_27647845 1.67 ENSDART00000151625
si:ch211-157c3.4
si:ch211-157c3.4
chr15_+_781717 1.65 ENSDART00000154903
znf970
zinc finger protein 970
chr8_+_11471350 1.64 ENSDART00000092355
ENSDART00000136184
tjp2b
tight junction protein 2b (zona occludens 2)
chr2_-_1622641 1.64 ENSDART00000082143
prkacbb
protein kinase, cAMP-dependent, catalytic, beta b
chr16_-_41488023 1.63 ENSDART00000169312
cmtm6
CKLF-like MARVEL transmembrane domain containing 6
chr12_-_13905307 1.62 ENSDART00000152400
dbf4b
DBF4 zinc finger B
chr8_-_1838315 1.61 ENSDART00000114476
ENSDART00000140077
pi4kab
phosphatidylinositol 4-kinase, catalytic, alpha b
chr9_+_8364553 1.60 ENSDART00000190713
si:dkey-90l23.2
si:dkey-90l23.2
chr14_+_41318412 1.58 ENSDART00000064614
xkrx
XK, Kell blood group complex subunit-related, X-linked
chr11_-_15850794 1.58 ENSDART00000185946
rap1ab
RAP1A, member of RAS oncogene family b
chr6_-_1432200 1.56 ENSDART00000182901
LO018148.1

chr6_+_10333920 1.55 ENSDART00000151667
ENSDART00000151477
cobll1a
cordon-bleu WH2 repeat protein-like 1a
chr20_-_31252809 1.54 ENSDART00000137236
hpcal1
hippocalcin-like 1
chr21_+_43172506 1.51 ENSDART00000121725
zcchc10
zinc finger, CCHC domain containing 10
chr15_-_5901514 1.49 ENSDART00000155252
si:ch73-281n10.2
si:ch73-281n10.2
chr7_+_27603211 1.49 ENSDART00000148782
cyp2r1
cytochrome P450, family 2, subfamily R, polypeptide 1
chr9_-_21098413 1.49 ENSDART00000018570
wars2
tryptophanyl tRNA synthetase 2, mitochondrial
chr3_-_60589292 1.47 ENSDART00000157822
jmjd6
jumonji domain containing 6
chr5_-_15494164 1.46 ENSDART00000140668
ENSDART00000188076
ENSDART00000085943
taok3a
TAO kinase 3a
chr16_-_8132742 1.46 ENSDART00000104323
snrka
SNF related kinase a
chr4_-_7876005 1.46 ENSDART00000109252
nudt5
nudix (nucleoside diphosphate linked moiety X)-type motif 5
chr11_+_31380495 1.45 ENSDART00000185073
sipa1l2
signal-induced proliferation-associated 1 like 2
chr2_-_49031303 1.42 ENSDART00000143471
cdc34b
cell division cycle 34 homolog (S. cerevisiae) b
chr20_-_23426339 1.42 ENSDART00000004625
zar1
zygote arrest 1
chr7_+_36467796 1.42 ENSDART00000146202
aktip
akt interacting protein
chr1_+_45925150 1.41 ENSDART00000074689
eif5b
eukaryotic translation initiation factor 5B
chr11_+_43740949 1.38 ENSDART00000189296
CU862021.1

chr17_+_13031497 1.37 ENSDART00000115208
fbxo33
F-box protein 33
chr9_+_22632126 1.37 ENSDART00000139434
etv5a
ets variant 5a
chr21_+_37477001 1.36 ENSDART00000114778
amot
angiomotin
chr2_-_22530969 1.36 ENSDART00000159641
znf644a
zinc finger protein 644a
chr8_-_15129573 1.35 ENSDART00000142358
bcar3
BCAR3, NSP family adaptor protein
chr6_+_12527725 1.35 ENSDART00000149328
stk24b
serine/threonine kinase 24b (STE20 homolog, yeast)
chr21_+_33311622 1.35 ENSDART00000163808
si:ch211-151g22.1
si:ch211-151g22.1
chr19_-_20106486 1.35 ENSDART00000043924
mpp6b
membrane protein, palmitoylated 6b (MAGUK p55 subfamily member 6)
chr19_+_43684376 1.34 ENSDART00000051723
si:ch211-193k19.1
si:ch211-193k19.1
chr20_-_28698172 1.34 ENSDART00000190635
sipa1l1
signal-induced proliferation-associated 1 like 1
chr19_+_41479990 1.32 ENSDART00000087187
ago2
argonaute RISC catalytic component 2
chr14_-_21618005 1.32 ENSDART00000043162
reep2
receptor accessory protein 2
chr9_+_33340311 1.32 ENSDART00000140064
ddx3a
DEAD (Asp-Glu-Ala-Asp) box helicase 3a
chr9_-_49964810 1.32 ENSDART00000167098
scn1a
sodium channel, voltage-gated, type I, alpha
chr3_-_3439150 1.30 ENSDART00000021286
A2ML1 (1 of many)
si:dkey-46g23.5
chr3_-_30488063 1.30 ENSDART00000055393
ENSDART00000151367
med25
mediator complex subunit 25
chr8_+_13364950 1.29 ENSDART00000159760
slc5a5
solute carrier family 5 (sodium/iodide cotransporter), member 5
chr21_+_19319804 1.29 ENSDART00000063621
abraxas2a
abraxas 2a, BRISC complex subunit
chr7_+_71955486 1.29 ENSDART00000189349
CABZ01071171.1
Danio rerio low density lipoprotein receptor-related protein 4 (lrp4), mRNA.
chr14_+_5835134 1.29 ENSDART00000054867
aup1
ancient ubiquitous protein 1
chr16_+_25068576 1.28 ENSDART00000125838
im:7147486
im:7147486
chr5_+_60518611 1.28 ENSDART00000130565
ENSDART00000186310
tmem132e
transmembrane protein 132E
chr9_+_43799829 1.28 ENSDART00000186240
ube2e3
ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast)
chr9_-_30247961 1.27 ENSDART00000131519
si:dkey-100n23.3
si:dkey-100n23.3
chr13_-_6279684 1.26 ENSDART00000092105
agpat5
1-acylglycerol-3-phosphate O-acyltransferase 5 (lysophosphatidic acid acyltransferase, epsilon)
chr24_-_18809433 1.26 ENSDART00000152009
arfgef1
ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
chr25_+_33033633 1.26 ENSDART00000192336
tln2b
talin 2b
chr16_-_8120203 1.25 ENSDART00000193430
snrka
SNF related kinase a
chr17_+_49637257 1.24 ENSDART00000075281
ENSDART00000065917
ENSDART00000123641
zgc:113372
zgc:113372
chr23_+_27789795 1.24 ENSDART00000141458
kmt2d
lysine (K)-specific methyltransferase 2D
chr17_-_10498347 1.23 ENSDART00000171324
mipol1
mirror-image polydactyly 1
chr12_+_33320884 1.23 ENSDART00000188988
csnk1db
casein kinase 1, delta b
chr20_+_32523576 1.23 ENSDART00000147319
scml4
Scm polycomb group protein like 4
chr19_-_23914743 1.22 ENSDART00000139856
chtopa
chromatin target of PRMT1a
chr19_-_47832853 1.19 ENSDART00000170988
ago4
argonaute RISC catalytic component 4
chr6_+_36821621 1.19 ENSDART00000104157
tmem45a
transmembrane protein 45a
chr15_-_28587147 1.18 ENSDART00000156049
ssh2a
slingshot protein phosphatase 2a
chr2_-_45135591 1.18 ENSDART00000014691
ENSDART00000123916
eif4e2
eukaryotic translation initiation factor 4E family member 2
chr4_+_25607743 1.16 ENSDART00000028297
acot14
acyl-CoA thioesterase 14
chr2_+_1939391 1.16 ENSDART00000163310
exosc4
exosome component 4
chr3_+_23047977 1.15 ENSDART00000155792
b4galnt2.2
beta-1,4-N-acetyl-galactosaminyl transferase 2, tandem duplicate 2
chr8_-_50888806 1.15 ENSDART00000053750
acsl2
acyl-CoA synthetase long chain family member 2
chr6_+_19948043 1.14 ENSDART00000182636
pik3r5
phosphoinositide-3-kinase, regulatory subunit 5
chr15_-_33304133 1.14 ENSDART00000186092
nbeab
neurobeachin b
chr10_+_10313024 1.13 ENSDART00000142895
ENSDART00000129952
urm1
ubiquitin related modifier 1
chr5_+_28260158 1.12 ENSDART00000181434
ncaph
non-SMC condensin I complex, subunit H
chr7_+_20917966 1.11 ENSDART00000129161
wrap53
WD repeat containing, antisense to TP53
chr25_-_7670616 1.10 ENSDART00000131583
ENSDART00000142794
bet1l
Bet1 golgi vesicular membrane trafficking protein-like
chr6_-_3982783 1.10 ENSDART00000171944
slc25a12
solute carrier family 25 (aspartate/glutamate carrier), member 12
chr7_-_21905851 1.09 ENSDART00000111066
ENSDART00000020288
epoa
erythropoietin a
chr13_-_36525982 1.09 ENSDART00000114744
pacs2
phosphofurin acidic cluster sorting protein 2
chr16_-_17316440 1.08 ENSDART00000147615
zyx
zyxin
chr3_-_27868183 1.08 ENSDART00000185812
abat
4-aminobutyrate aminotransferase
chr2_+_31942390 1.08 ENSDART00000138684
ENSDART00000146758
ENSDART00000137921
otulinb
OTU deubiquitinase with linear linkage specificity b
chr6_-_40778294 1.08 ENSDART00000019845
arpc4
actin related protein 2/3 complex, subunit 4
chr5_-_32336613 1.08 ENSDART00000139732
dab2
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr7_-_40959667 1.07 ENSDART00000084070
rbm33a
RNA binding motif protein 33a
chr5_-_22052852 1.07 ENSDART00000002938
mtmr8
myotubularin related protein 8
chr23_-_31645760 1.06 ENSDART00000035031
sgk1
serum/glucocorticoid regulated kinase 1
chr14_-_46617228 1.06 ENSDART00000161010
ENSDART00000171054
prom1a
prominin 1a
chr6_-_29051773 1.04 ENSDART00000190508
ENSDART00000180191
ENSDART00000111682
evi5b
ecotropic viral integration site 5b
chr25_-_7918526 1.04 ENSDART00000104686
ENSDART00000156761
ambra1b
autophagy/beclin-1 regulator 1b
chr12_+_13905286 1.04 ENSDART00000147186
fkbp10b
FK506 binding protein 10b
chr4_-_73411863 1.04 ENSDART00000171434
zgc:162958
zgc:162958
chr13_+_37656278 1.03 ENSDART00000193251
phf3
PHD finger protein 3
chr22_-_6562618 1.03 ENSDART00000106100
zgc:171490
zgc:171490
chr9_+_29430432 1.03 ENSDART00000125632
uggt2
UDP-glucose glycoprotein glucosyltransferase 2
chr15_+_24795473 1.03 ENSDART00000139689
ENSDART00000141033
ENSDART00000100746
ENSDART00000135677
gosr1
golgi SNAP receptor complex member 1
chr6_-_40657653 1.02 ENSDART00000154359
ppil1
peptidylprolyl isomerase (cyclophilin)-like 1
chr15_-_31177324 1.02 ENSDART00000008854
wsb1
WD repeat and SOCS box containing 1
chr23_-_27505825 1.01 ENSDART00000137229
ENSDART00000013797
asb8
ankyrin repeat and SOCS box containing 8
chr9_+_6079528 1.01 ENSDART00000142167
st6gal2a
ST6 beta-galactosamide alpha-2,6-sialyltranferase 2a
chr13_-_4134141 1.01 ENSDART00000132354
tjap1
tight junction associated protein 1 (peripheral)
chr6_+_40922572 1.01 ENSDART00000133599
ENSDART00000002728
ENSDART00000145153
eif4enif1
eukaryotic translation initiation factor 4E nuclear import factor 1
chr9_-_12659140 1.01 ENSDART00000058565
pttg1ipb
PTTG1 interacting protein b
chr10_+_585719 1.01 ENSDART00000180167
smad4a
SMAD family member 4a
chr13_-_25750910 1.01 ENSDART00000111567
sgpl1
sphingosine-1-phosphate lyase 1
chr1_+_1712140 1.00 ENSDART00000081047
atp1a1a.1
ATPase Na+/K+ transporting subunit alpha 1a, tandem duplicate 1
chr17_-_51262430 1.00 ENSDART00000163222
trappc12
trafficking protein particle complex 12
chr19_+_8612839 1.00 ENSDART00000144925
snx27a
sorting nexin family member 27a
chr15_-_14083028 0.99 ENSDART00000147796
ENSDART00000043492
ENSDART00000133080
trappc6bl
trafficking protein particle complex 6b-like
chr6_-_10037207 0.98 ENSDART00000179701
nudt15
nudix (nucleoside diphosphate linked moiety X)-type motif 15
chr2_+_49805892 0.98 ENSDART00000056248
wdr48b
WD repeat domain 48b
chr5_-_54481692 0.98 ENSDART00000165719
fbxw5
F-box and WD repeat domain containing 5
chr8_+_16676894 0.98 ENSDART00000076586
si:ch211-198n5.11
si:ch211-198n5.11
chr16_-_10223741 0.98 ENSDART00000188099
si:rp71-15i12.1
si:rp71-15i12.1
chr7_-_30280934 0.97 ENSDART00000126741
serf2
small EDRK-rich factor 2
chr2_+_24080694 0.97 ENSDART00000024058
kcnh2a
potassium voltage-gated channel, subfamily H (eag-related), member 2a
chr23_+_22785375 0.97 ENSDART00000142085
rerea
arginine-glutamic acid dipeptide (RE) repeats a
chr14_+_45028062 0.97 ENSDART00000184717
ENSDART00000185481
ATP8A1
ATPase phospholipid transporting 8A1
chr4_-_5019113 0.96 ENSDART00000189321
ENSDART00000081990
strip2
striatin interacting protein 2
chr2_-_26596794 0.95 ENSDART00000134685
ENSDART00000056787
zgc:113691
zgc:113691
chr10_-_41397663 0.94 ENSDART00000158038
gpat4
glycerol-3-phosphate acyltransferase 4
chr9_-_34260214 0.93 ENSDART00000012385
me3
malic enzyme 3, NADP(+)-dependent, mitochondrial
chr17_-_2721336 0.92 ENSDART00000109582
ENSDART00000192691
ENSDART00000189381
spata7
spermatogenesis associated 7
chr3_+_35498119 0.91 ENSDART00000178963
tnrc6a
trinucleotide repeat containing 6a
chr18_-_40913294 0.91 ENSDART00000059196
ENSDART00000098878
polr2i
polymerase (RNA) II (DNA directed) polypeptide I
chr24_+_11908833 0.91 ENSDART00000178622
fen1
flap structure-specific endonuclease 1
chr19_+_20787179 0.90 ENSDART00000193204
adnp2b
ADNP homeobox 2b
chr15_-_14194208 0.89 ENSDART00000188237
ENSDART00000183155
ENSDART00000165520
pnkp
polynucleotide kinase 3'-phosphatase
chr16_-_9869056 0.89 ENSDART00000149312
ncalda
neurocalcin delta a
chr15_-_20709289 0.89 ENSDART00000136767
tpst1
tyrosylprotein sulfotransferase 1
chr12_+_33320504 0.89 ENSDART00000021491
csnk1db
casein kinase 1, delta b
chr8_-_8349653 0.89 ENSDART00000025214
tsr2
TSR2, 20S rRNA accumulation, homolog (S. cerevisiae)
chr2_+_55199721 0.88 ENSDART00000016143
zmp:0000000521
zmp:0000000521
chr1_+_45663727 0.88 ENSDART00000038574
ENSDART00000141144
ENSDART00000149565
trappc5
trafficking protein particle complex 5
chr19_+_42328423 0.88 ENSDART00000077059
anp32e
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr19_+_37925616 0.87 ENSDART00000148348
nxph1
neurexophilin 1
chr17_-_6955082 0.87 ENSDART00000109228
zbtb24
zinc finger and BTB domain containing 24
chr7_+_21752168 0.87 ENSDART00000173641
kdm6ba
lysine (K)-specific demethylase 6B, a

Network of associatons between targets according to the STRING database.

First level regulatory network of nr2e3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 1.6 GO:2000301 negative regulation of neurotransmitter secretion(GO:0046929) response to cAMP(GO:0051591) cellular response to cAMP(GO:0071320) negative regulation of synaptic vesicle transport(GO:1902804) negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.6 10.7 GO:0007339 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.6 2.8 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
0.5 2.2 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.5 3.7 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.5 4.3 GO:0003428 growth plate cartilage morphogenesis(GO:0003422) chondrocyte intercalation involved in growth plate cartilage morphogenesis(GO:0003428)
0.4 4.7 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.4 1.7 GO:0019464 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.4 2.1 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.4 3.2 GO:0040038 meiotic cytokinesis(GO:0033206) polar body extrusion after meiotic divisions(GO:0040038)
0.4 3.2 GO:0006561 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.3 1.0 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
0.3 1.7 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.3 1.2 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.3 2.4 GO:0043363 nucleate erythrocyte differentiation(GO:0043363)
0.3 0.5 GO:0090085 regulation of protein deubiquitination(GO:0090085)
0.3 0.5 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.3 0.8 GO:0048917 posterior lateral line ganglion development(GO:0048917)
0.2 1.5 GO:0071305 vitamin D3 metabolic process(GO:0070640) cellular response to vitamin D(GO:0071305)
0.2 1.6 GO:2000105 positive regulation of DNA-dependent DNA replication(GO:2000105)
0.2 0.7 GO:0010039 response to iron ion(GO:0010039)
0.2 1.2 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.2 1.1 GO:0030576 nuclear body organization(GO:0030575) Cajal body organization(GO:0030576)
0.2 1.1 GO:0009450 gamma-aminobutyric acid catabolic process(GO:0009450)
0.2 1.9 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.2 1.0 GO:0048209 regulation of vesicle targeting, to, from or within Golgi(GO:0048209)
0.2 0.6 GO:0035046 pronuclear migration(GO:0035046)
0.2 0.8 GO:0032211 negative regulation of telomere maintenance via telomerase(GO:0032211) negative regulation of telomere maintenance via telomere lengthening(GO:1904357)
0.2 2.5 GO:0098734 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.2 1.2 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.2 1.1 GO:0032447 protein urmylation(GO:0032447)
0.2 1.3 GO:0034389 lipid particle organization(GO:0034389)
0.2 1.1 GO:1990108 protein linear deubiquitination(GO:1990108)
0.2 1.4 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.2 0.8 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.2 0.8 GO:0006011 UDP-glucose metabolic process(GO:0006011)
0.2 0.6 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.2 1.9 GO:0033198 response to ATP(GO:0033198)
0.2 2.1 GO:0035278 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.1 0.6 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.1 1.0 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.1 1.8 GO:0006991 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.1 1.0 GO:0006552 leucine catabolic process(GO:0006552)
0.1 0.7 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.1 2.5 GO:0048922 posterior lateral line neuromast deposition(GO:0048922)
0.1 2.3 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.1 1.4 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.1 1.1 GO:2000725 regulation of cardiocyte differentiation(GO:1905207) regulation of cardiac muscle cell differentiation(GO:2000725)
0.1 0.7 GO:0042766 nucleosome mobilization(GO:0042766)
0.1 0.3 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.1 0.4 GO:0002188 translation reinitiation(GO:0002188)
0.1 0.9 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.1 1.3 GO:0035677 posterior lateral line neuromast hair cell development(GO:0035677)
0.1 1.1 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.1 1.2 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.1 1.0 GO:0046070 dGTP catabolic process(GO:0006203) purine nucleoside triphosphate catabolic process(GO:0009146) purine deoxyribonucleoside triphosphate catabolic process(GO:0009217) dGTP metabolic process(GO:0046070)
0.1 0.9 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.1 0.7 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.1 1.0 GO:0031063 regulation of histone deacetylation(GO:0031063)
0.1 1.3 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.1 1.3 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.1 0.3 GO:0051039 histone displacement(GO:0001207) regulation of transcription involved in meiotic cell cycle(GO:0051037) positive regulation of transcription involved in meiotic cell cycle(GO:0051039)
0.1 0.5 GO:0042117 monocyte activation(GO:0042117)
0.1 0.5 GO:0015074 DNA integration(GO:0015074)
0.1 0.7 GO:1905066 regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066)
0.1 0.9 GO:0006477 protein sulfation(GO:0006477) peptidyl-tyrosine sulfation(GO:0006478)
0.1 1.1 GO:0015813 acidic amino acid transport(GO:0015800) aspartate transport(GO:0015810) L-glutamate transport(GO:0015813) malate-aspartate shuttle(GO:0043490)
0.1 0.6 GO:0030242 pexophagy(GO:0030242)
0.1 2.2 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.1 1.5 GO:0055117 regulation of cardiac muscle contraction(GO:0055117)
0.1 1.8 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.1 0.5 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.1 1.3 GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
0.1 2.0 GO:0000959 mitochondrial RNA metabolic process(GO:0000959)
0.1 1.4 GO:0098927 early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.1 0.6 GO:2000178 negative regulation of neural precursor cell proliferation(GO:2000178)
0.1 1.1 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.1 0.4 GO:0043111 replication fork arrest(GO:0043111)
0.1 0.5 GO:0017062 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.1 1.9 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.1 1.1 GO:0016926 protein desumoylation(GO:0016926)
0.1 0.4 GO:0034553 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.1 0.8 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.1 0.3 GO:0015722 canalicular bile acid transport(GO:0015722) bile acid secretion(GO:0032782)
0.1 0.5 GO:0097101 blood vessel endothelial cell fate specification(GO:0097101)
0.1 1.4 GO:0060021 palate development(GO:0060021)
0.1 2.2 GO:0030488 tRNA methylation(GO:0030488)
0.1 0.3 GO:1902373 negative regulation of RNA catabolic process(GO:1902369) negative regulation of mRNA catabolic process(GO:1902373) regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.1 1.6 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.1 1.0 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.1 0.4 GO:0048795 swim bladder morphogenesis(GO:0048795)
0.1 1.4 GO:0034626 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 1.4 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.1 0.2 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.1 0.4 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.1 0.4 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.1 0.1 GO:0009155 purine deoxyribonucleotide catabolic process(GO:0009155)
0.1 0.2 GO:0070914 UV-damage excision repair(GO:0070914)
0.1 1.3 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.1 0.5 GO:2000479 regulation of cAMP-dependent protein kinase activity(GO:2000479)
0.1 0.4 GO:0021535 cell migration in hindbrain(GO:0021535)
0.1 0.2 GO:1903723 negative regulation of centriole elongation(GO:1903723)
0.1 0.8 GO:0060325 face morphogenesis(GO:0060325)
0.1 0.7 GO:2000142 regulation of transcription initiation from RNA polymerase II promoter(GO:0060260) regulation of DNA-templated transcription, initiation(GO:2000142)
0.1 2.4 GO:0042752 regulation of circadian rhythm(GO:0042752)
0.1 6.7 GO:0090630 activation of GTPase activity(GO:0090630)
0.1 0.2 GO:0006590 thyroid hormone generation(GO:0006590)
0.1 2.5 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.1 0.5 GO:0006108 malate metabolic process(GO:0006108)
0.1 0.8 GO:0061154 endothelial tube morphogenesis(GO:0061154) blood vessel lumenization(GO:0072554)
0.1 3.8 GO:1902652 cholesterol metabolic process(GO:0008203) secondary alcohol metabolic process(GO:1902652)
0.1 0.8 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.6 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.0 5.2 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 1.0 GO:0010824 regulation of centrosome duplication(GO:0010824)
0.0 0.8 GO:0060173 limb development(GO:0060173)
0.0 0.6 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.0 0.5 GO:0001836 release of cytochrome c from mitochondria(GO:0001836)
0.0 0.2 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.6 GO:0010996 response to auditory stimulus(GO:0010996)
0.0 0.4 GO:0007176 regulation of epidermal growth factor-activated receptor activity(GO:0007176)
0.0 0.4 GO:0021634 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083) optic nerve formation(GO:0021634)
0.0 0.7 GO:0072698 protein localization to microtubule cytoskeleton(GO:0072698)
0.0 1.1 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 1.7 GO:0006400 tRNA modification(GO:0006400)
0.0 0.3 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.0 0.5 GO:0035675 neuromast hair cell development(GO:0035675)
0.0 0.9 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 4.7 GO:0006413 translational initiation(GO:0006413)
0.0 0.4 GO:0038203 TORC2 signaling(GO:0038203)
0.0 1.1 GO:0016180 snRNA processing(GO:0016180)
0.0 0.9 GO:0010737 protein kinase A signaling(GO:0010737)
0.0 0.3 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.9 GO:0032474 otolith morphogenesis(GO:0032474)
0.0 0.2 GO:0033029 neutrophil apoptotic process(GO:0001781) regulation of T-helper 1 type immune response(GO:0002825) positive regulation of T-helper 1 type immune response(GO:0002827) negative regulation of type 2 immune response(GO:0002829) inflammatory cell apoptotic process(GO:0006925) regulation of prostaglandin biosynthetic process(GO:0031392) positive regulation of prostaglandin biosynthetic process(GO:0031394) regulation of phospholipase A2 activity(GO:0032429) interleukin-2 production(GO:0032623) regulation of interleukin-2 production(GO:0032663) positive regulation of interleukin-2 production(GO:0032743) myeloid cell apoptotic process(GO:0033028) regulation of neutrophil apoptotic process(GO:0033029) positive regulation of neutrophil apoptotic process(GO:0033031) regulation of myeloid cell apoptotic process(GO:0033032) positive regulation of myeloid cell apoptotic process(GO:0033034) T-helper 1 type immune response(GO:0042088) negative regulation of CD4-positive, alpha-beta T cell differentiation(GO:0043371) positive regulation of CD4-positive, alpha-beta T cell differentiation(GO:0043372) T-helper 1 cell differentiation(GO:0045063) negative regulation of T cell differentiation(GO:0045581) regulation of T-helper cell differentiation(GO:0045622) negative regulation of T-helper cell differentiation(GO:0045623) positive regulation of T-helper cell differentiation(GO:0045624) regulation of T-helper 1 cell differentiation(GO:0045625) positive regulation of T-helper 1 cell differentiation(GO:0045627) regulation of T-helper 2 cell differentiation(GO:0045628) negative regulation of T-helper 2 cell differentiation(GO:0045629) positive regulation of fatty acid biosynthetic process(GO:0045723) positive regulation of alpha-beta T cell differentiation(GO:0046638) negative regulation of alpha-beta T cell differentiation(GO:0046639) neutrophil clearance(GO:0097350) negative regulation of phospholipase A2 activity(GO:1900138) positive regulation of CD4-positive, alpha-beta T cell activation(GO:2000516) regulation of unsaturated fatty acid biosynthetic process(GO:2001279) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.0 1.5 GO:0046466 sphingolipid catabolic process(GO:0030149) membrane lipid catabolic process(GO:0046466)
0.0 0.4 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.9 GO:0043486 histone exchange(GO:0043486)
0.0 0.1 GO:0072512 ferric iron transport(GO:0015682) transferrin transport(GO:0033572) trivalent inorganic cation transport(GO:0072512)
0.0 0.4 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0 0.8 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.0 0.2 GO:0071405 response to methanol(GO:0033986) cellular response to methanol(GO:0071405)
0.0 0.3 GO:0043981 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 0.2 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.1 GO:0061549 sympathetic ganglion development(GO:0061549)
0.0 0.6 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 1.2 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.1 GO:0021985 parturition(GO:0007567) neurohypophysis development(GO:0021985) maternal process involved in parturition(GO:0060137)
0.0 0.1 GO:0016038 absorption of visible light(GO:0016038)
0.0 0.6 GO:0030038 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.0 0.9 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.3 GO:0009648 photoperiodism(GO:0009648)
0.0 0.5 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 2.0 GO:0006637 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.0 0.4 GO:0036065 fucosylation(GO:0036065)
0.0 0.4 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.2 GO:0016119 carotene metabolic process(GO:0016119) carotene catabolic process(GO:0016121) terpene metabolic process(GO:0042214) terpene catabolic process(GO:0046247)
0.0 0.5 GO:0080111 DNA demethylation(GO:0080111)
0.0 0.2 GO:0060753 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0 1.6 GO:0090263 positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.0 0.3 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 2.1 GO:0071559 transforming growth factor beta receptor signaling pathway(GO:0007179) response to transforming growth factor beta(GO:0071559) cellular response to transforming growth factor beta stimulus(GO:0071560)
0.0 0.8 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 1.2 GO:0099515 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.0 0.1 GO:1990089 response to nerve growth factor(GO:1990089) cellular response to nerve growth factor stimulus(GO:1990090)
0.0 1.5 GO:0032147 activation of protein kinase activity(GO:0032147)
0.0 1.1 GO:0016575 histone deacetylation(GO:0016575)
0.0 0.1 GO:0003403 optic vesicle formation(GO:0003403)
0.0 1.7 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.1 GO:0038065 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065)
0.0 1.4 GO:0017148 negative regulation of translation(GO:0017148)
0.0 0.2 GO:1901998 toxin transport(GO:1901998)
0.0 0.5 GO:0030223 neutrophil differentiation(GO:0030223)
0.0 1.2 GO:0034968 histone lysine methylation(GO:0034968)
0.0 2.2 GO:0045930 negative regulation of mitotic cell cycle(GO:0045930)
0.0 0.6 GO:0060037 pharyngeal system development(GO:0060037)
0.0 1.0 GO:0007030 Golgi organization(GO:0007030)
0.0 0.8 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.5 GO:0030301 cholesterol transport(GO:0030301)
0.0 0.5 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.4 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 0.1 GO:0016322 neuron remodeling(GO:0016322)
0.0 1.2 GO:0043406 positive regulation of MAP kinase activity(GO:0043406)
0.0 0.1 GO:1901492 positive regulation of lymphangiogenesis(GO:1901492)
0.0 0.4 GO:0046834 lipid phosphorylation(GO:0046834)
0.0 0.1 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.0 0.1 GO:0039703 viral genome replication(GO:0019079) negative stranded viral RNA replication(GO:0039689) viral RNA genome replication(GO:0039694) RNA replication(GO:0039703) multi-organism metabolic process(GO:0044033) multi-organism biosynthetic process(GO:0044034)
0.0 1.1 GO:0061640 cytoskeleton-dependent cytokinesis(GO:0061640)
0.0 0.2 GO:0021988 olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988)
0.0 0.1 GO:0060017 parathyroid gland development(GO:0060017)
0.0 0.3 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.6 GO:0060389 pathway-restricted SMAD protein phosphorylation(GO:0060389)
0.0 0.2 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.3 GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0006919)
0.0 0.2 GO:0001522 pseudouridine synthesis(GO:0001522)
0.0 0.5 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 0.1 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.3 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.7 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 0.6 GO:0051607 defense response to virus(GO:0051607)
0.0 0.8 GO:0090174 vesicle fusion(GO:0006906) organelle membrane fusion(GO:0090174)
0.0 0.2 GO:0015693 magnesium ion transport(GO:0015693)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 1.0 GO:0005797 Golgi medial cisterna(GO:0005797)
0.4 1.3 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.3 2.5 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.3 0.9 GO:1990072 TRAPPIII protein complex(GO:1990072)
0.3 1.9 GO:0000138 Golgi trans cisterna(GO:0000138)
0.3 3.7 GO:0034361 very-low-density lipoprotein particle(GO:0034361)
0.3 1.3 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.2 1.4 GO:0070695 FHF complex(GO:0070695)
0.2 1.8 GO:0044232 organelle membrane contact site(GO:0044232)
0.2 0.6 GO:0019185 snRNA-activating protein complex(GO:0019185)
0.2 4.0 GO:0044666 MLL3/4 complex(GO:0044666)
0.2 0.8 GO:1990498 mitotic spindle microtubule(GO:1990498)
0.2 1.6 GO:0071797 LUBAC complex(GO:0071797)
0.1 2.0 GO:0030008 TRAPP complex(GO:0030008)
0.1 1.1 GO:0000796 condensin complex(GO:0000796)
0.1 1.1 GO:0071914 prominosome(GO:0071914)
0.1 0.5 GO:0044609 DBIRD complex(GO:0044609)
0.1 1.2 GO:0005688 U6 snRNP(GO:0005688)
0.1 1.2 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.1 2.6 GO:0071565 nBAF complex(GO:0071565)
0.1 1.3 GO:0098827 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.1 1.2 GO:0016580 Sin3 complex(GO:0016580)
0.1 0.6 GO:0000938 GARP complex(GO:0000938)
0.1 1.9 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.1 2.1 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.1 1.6 GO:0005903 brush border(GO:0005903)
0.1 0.6 GO:0045261 proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.1 0.4 GO:0031298 replication fork protection complex(GO:0031298)
0.1 2.2 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.1 0.9 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1 1.1 GO:0097651 phosphatidylinositol 3-kinase complex, class IB(GO:0005944) phosphatidylinositol 3-kinase complex, class I(GO:0097651)
0.1 0.3 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.1 0.7 GO:0000812 Swr1 complex(GO:0000812)
0.1 1.7 GO:0005637 nuclear inner membrane(GO:0005637)
0.1 0.4 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1 0.3 GO:1990513 CLOCK-BMAL transcription complex(GO:1990513)
0.1 1.1 GO:0015030 Cajal body(GO:0015030)
0.1 1.2 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 2.6 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 1.3 GO:0071141 SMAD protein complex(GO:0071141)
0.1 2.1 GO:0005876 spindle microtubule(GO:0005876)
0.1 0.6 GO:0097431 mitotic spindle pole(GO:0097431)
0.1 0.4 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.0 0.7 GO:0097346 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202) INO80-type complex(GO:0097346)
0.0 0.2 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.6 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.6 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.1 GO:0005592 collagen type XI trimer(GO:0005592)
0.0 4.6 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.6 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.7 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.5 GO:1902562 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 0.7 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.4 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 2.1 GO:0031228 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 0.7 GO:0034399 nuclear periphery(GO:0034399)
0.0 0.7 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 4.0 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.1 GO:0061702 inflammasome complex(GO:0061702)
0.0 0.4 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.4 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.8 GO:0005940 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.8 GO:0031941 filamentous actin(GO:0031941)
0.0 0.5 GO:0032039 integrator complex(GO:0032039)
0.0 1.5 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.2 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.5 GO:0071004 U2-type prespliceosome(GO:0071004) prespliceosome(GO:0071010)
0.0 1.5 GO:0032432 actin filament bundle(GO:0032432)
0.0 0.4 GO:0030057 desmosome(GO:0030057)
0.0 0.2 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 3.5 GO:0016604 nuclear body(GO:0016604)
0.0 1.1 GO:0030496 midbody(GO:0030496)
0.0 0.5 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.3 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.0 1.4 GO:0031902 late endosome membrane(GO:0031902)
0.0 0.2 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 1.3 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.4 GO:0031932 TORC2 complex(GO:0031932)
0.0 1.0 GO:0005770 late endosome(GO:0005770)
0.0 0.9 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.2 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.2 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.0 GO:0042709 succinate-CoA ligase complex(GO:0042709)
0.0 0.9 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.3 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.1 GO:0043083 synaptic cleft(GO:0043083)
0.0 2.2 GO:0010008 endosome membrane(GO:0010008)
0.0 0.2 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.0 0.8 GO:0001726 ruffle(GO:0001726)
0.0 3.0 GO:0030659 cytoplasmic vesicle membrane(GO:0030659)
0.0 1.0 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 3.3 GO:0005730 nucleolus(GO:0005730)
0.0 0.3 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.5 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.3 GO:0072686 mitotic spindle(GO:0072686)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 10.7 GO:0035804 structural constituent of egg coat(GO:0035804)
0.9 3.7 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
0.9 2.8 GO:0008386 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.7 4.7 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.6 3.2 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.5 1.5 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.4 1.5 GO:0008117 sphinganine-1-phosphate aldolase activity(GO:0008117)
0.4 1.1 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.3 1.3 GO:0070883 pre-miRNA binding(GO:0070883)
0.3 1.6 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.3 1.0 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.3 0.9 GO:0046403 polynucleotide 3'-phosphatase activity(GO:0046403)
0.3 0.8 GO:0008517 folic acid transporter activity(GO:0008517)
0.3 1.8 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.2 2.1 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.2 0.9 GO:0004471 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.2 0.7 GO:0003994 aconitate hydratase activity(GO:0003994)
0.2 1.6 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.2 1.3 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.2 1.0 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.2 1.2 GO:0017070 U6 snRNA binding(GO:0017070)
0.2 0.6 GO:0001605 adrenomedullin receptor activity(GO:0001605) calcitonin gene-related peptide receptor activity(GO:0001635)
0.2 1.2 GO:0001091 RNA polymerase II basal transcription factor binding(GO:0001091)
0.2 1.7 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.2 1.3 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.2 3.6 GO:0036002 pre-mRNA binding(GO:0036002)
0.2 0.8 GO:0051748 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.2 1.0 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.2 0.5 GO:1901612 cardiolipin binding(GO:1901612)
0.2 1.9 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.2 0.9 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.1 1.2 GO:0035198 miRNA binding(GO:0035198)
0.1 3.4 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1 1.3 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.1 1.1 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.1 1.0 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.1 1.2 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.1 0.9 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.1 0.4 GO:0032184 SUMO polymer binding(GO:0032184)
0.1 2.5 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 0.8 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.1 1.8 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 1.2 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1 0.6 GO:0008311 double-stranded DNA exodeoxyribonuclease activity(GO:0008309) double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.1 0.9 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.1 1.1 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.1 1.5 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.1 0.9 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 0.4 GO:0015105 arsenite transmembrane transporter activity(GO:0015105)
0.1 1.0 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1 2.8 GO:0008483 transaminase activity(GO:0008483)
0.1 1.1 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.1 0.6 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.1 0.5 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.1 4.5 GO:0015485 cholesterol binding(GO:0015485)
0.1 2.0 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.1 4.1 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.1 5.6 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 1.2 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.1 0.5 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427) calcium-dependent protein kinase regulator activity(GO:0010858)
0.1 1.6 GO:0003785 actin monomer binding(GO:0003785)
0.1 0.7 GO:0017091 AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 0.2 GO:0071568 UFM1 transferase activity(GO:0071568)
0.1 0.3 GO:0015126 canalicular bile acid transmembrane transporter activity(GO:0015126) bile acid-exporting ATPase activity(GO:0015432)
0.1 4.3 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 1.1 GO:0031386 protein tag(GO:0031386)
0.1 1.4 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 0.2 GO:0003909 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.1 3.2 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 2.2 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.1 2.2 GO:0019003 GDP binding(GO:0019003)
0.1 0.5 GO:0031628 opioid receptor binding(GO:0031628)
0.1 1.5 GO:0016876 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.1 1.1 GO:0001671 ATPase activator activity(GO:0001671)
0.1 0.6 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 1.7 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 0.2 GO:0070699 beta-1 adrenergic receptor binding(GO:0031697) type II activin receptor binding(GO:0070699)
0.1 0.4 GO:0035173 histone kinase activity(GO:0035173)
0.1 0.7 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.1 0.4 GO:0030274 LIM domain binding(GO:0030274)
0.1 1.6 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.1 13.9 GO:0030246 carbohydrate binding(GO:0030246)
0.1 1.0 GO:0070411 I-SMAD binding(GO:0070411)
0.1 0.7 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.6 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.3 GO:0070888 E-box binding(GO:0070888)
0.0 0.8 GO:0070566 adenylyltransferase activity(GO:0070566)
0.0 0.6 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.6 GO:0070740 protein-glutamic acid ligase activity(GO:0070739) tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.6 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.9 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 3.4 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 1.8 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.1 GO:0005502 11-cis retinal binding(GO:0005502)
0.0 1.6 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.6 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.2 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.6 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 1.2 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.4 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 1.2 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.1 GO:0004998 transferrin receptor activity(GO:0004998)
0.0 0.4 GO:0031995 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
0.0 0.3 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.9 GO:0034062 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.6 GO:0002039 p53 binding(GO:0002039)
0.0 0.3 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.7 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.2 GO:0034632 retinol transporter activity(GO:0034632)
0.0 0.3 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.1 GO:0004990 oxytocin receptor activity(GO:0004990)
0.0 1.2 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.0 0.3 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 1.5 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 1.4 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.2 GO:0003834 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.0 0.1 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 2.1 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.2 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.7 GO:0051018 protein kinase A binding(GO:0051018)
0.0 8.9 GO:0005096 GTPase activator activity(GO:0005096)
0.0 1.5 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0 0.7 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.3 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 1.2 GO:0030898 microfilament motor activity(GO:0000146) actin-dependent ATPase activity(GO:0030898)
0.0 0.1 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.0 0.8 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 1.3 GO:0015370 solute:sodium symporter activity(GO:0015370)
0.0 0.5 GO:0031267 small GTPase binding(GO:0031267)
0.0 0.8 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.5 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.1 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 1.8 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.9 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.0 1.3 GO:0004527 exonuclease activity(GO:0004527)
0.0 0.4 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.1 GO:0030273 melanin-concentrating hormone receptor activity(GO:0030273)
0.0 0.3 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.0 1.5 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 2.2 GO:0042803 protein homodimerization activity(GO:0042803)
0.0 0.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.4 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 0.4 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.0 GO:0004775 succinate-CoA ligase activity(GO:0004774) succinate-CoA ligase (ADP-forming) activity(GO:0004775) succinate-CoA ligase (GDP-forming) activity(GO:0004776)
0.0 0.8 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 0.4 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.5 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 4.1 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.3 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.1 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.3 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 0.1 GO:0030250 cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.0 0.1 GO:0030172 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.0 1.4 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 0.1 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.2 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.5 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor(GO:0016620)
0.0 0.4 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 1.9 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 2.2 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.1 PID REELIN PATHWAY Reelin signaling pathway
0.1 1.5 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.1 1.1 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 1.1 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.1 1.2 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 1.3 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.1 1.9 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.1 1.8 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.1 2.2 PID PI3KCI PATHWAY Class I PI3K signaling events
0.1 0.4 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.5 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.0 1.5 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.8 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.1 PID AURORA B PATHWAY Aurora B signaling
0.0 1.7 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.7 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.4 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.5 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 1.0 PID CDC42 PATHWAY CDC42 signaling events
0.0 1.5 PID E2F PATHWAY E2F transcription factor network
0.0 0.6 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.4 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.0 0.1 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 1.0 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.4 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.4 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.8 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.2 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.3 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.3 3.2 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.3 1.2 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.2 4.7 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.2 1.7 REACTOME EARLY PHASE OF HIV LIFE CYCLE Genes involved in Early Phase of HIV Life Cycle
0.2 1.1 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.2 3.0 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.1 1.3 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.1 1.5 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.1 1.3 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.1 0.9 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.1 1.8 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.1 1.1 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.1 1.2 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1 1.5 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.1 1.4 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 1.0 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 0.8 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 1.1 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 0.8 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.1 1.5 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 1.6 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.5 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.0 2.1 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.4 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 7.6 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.5 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 0.7 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.5 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 1.0 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 0.3 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.2 REACTOME OPSINS Genes involved in Opsins
0.0 0.4 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 0.5 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 1.2 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.7 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.2 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.1 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.4 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.8 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.8 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.2 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.1 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.1 REACTOME NGF SIGNALLING VIA TRKA FROM THE PLASMA MEMBRANE Genes involved in NGF signalling via TRKA from the plasma membrane
0.0 0.7 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.3 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.1 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine