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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for nr4a2a

Z-value: 0.36

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Transcription factors associated with nr4a2a

Gene Symbol Gene ID Gene Info
nr4a2a
ENSDARG00000017007 nuclear receptor subfamily 4, group A, member 2a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nr4a2adr11_v1_chr9_-_5046315_5046315-0.542.0e-02Click!

Activity profile of nr4a2a motif

Sorted Z-values of nr4a2a motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr16_+_53278406 0.99 ENSDART00000010792
ptdss1a
phosphatidylserine synthase 1a
chr19_-_42045372 0.97 ENSDART00000144275
trioa
trio Rho guanine nucleotide exchange factor a
chr18_+_45571378 0.76 ENSDART00000077251
kifc3
kinesin family member C3
chr21_-_7940043 0.75 ENSDART00000099733
ENSDART00000136671
f2rl1.1
coagulation factor II (thrombin) receptor-like 1, tandem duplicate 1
chr2_-_34138400 0.74 ENSDART00000056667
cenpl
centromere protein L
chr7_-_33684632 0.72 ENSDART00000130553
tle3b
transducin-like enhancer of split 3b
chr15_-_37875601 0.69 ENSDART00000122439
si:dkey-238d18.4
si:dkey-238d18.4
chr23_-_22523303 0.64 ENSDART00000079019
spsb1
splA/ryanodine receptor domain and SOCS box containing 1
chr17_+_17764979 0.63 ENSDART00000105013
alkbh1
alkB homolog 1, histone H2A dioxygenase
chr7_+_46020508 0.63 ENSDART00000170294
ccne1
cyclin E1
chr8_+_16758304 0.62 ENSDART00000133514
elovl7a
ELOVL fatty acid elongase 7a
chr19_-_47571456 0.59 ENSDART00000158071
ENSDART00000165841
rrm2
ribonucleotide reductase M2 polypeptide
chr24_-_21934571 0.58 ENSDART00000113092
tagln3b
transgelin 3b
chr11_-_39118882 0.58 ENSDART00000113185
ENSDART00000156526
ap5b1
adaptor-related protein complex 5, beta 1 subunit
chr14_+_30340251 0.57 ENSDART00000148448
mtus1a
microtubule associated tumor suppressor 1a
chr22_-_37834312 0.56 ENSDART00000076128
ppp1r2
protein phosphatase 1, regulatory (inhibitor) subunit 2
chr8_-_22542467 0.55 ENSDART00000182588
ENSDART00000134542
csde1
cold shock domain containing E1, RNA-binding
chr8_+_45338073 0.55 ENSDART00000185024
pabpc1l
poly(A) binding protein, cytoplasmic 1-like
chr20_-_29499363 0.54 ENSDART00000152889
ENSDART00000153252
ENSDART00000170972
ENSDART00000166420
ENSDART00000163079
rrm2
ribonucleotide reductase M2 polypeptide
chr5_-_54481692 0.53 ENSDART00000165719
fbxw5
F-box and WD repeat domain containing 5
chr14_+_35428152 0.53 ENSDART00000172597
sytl4
synaptotagmin-like 4
chr16_+_16266428 0.52 ENSDART00000188433
setd2
SET domain containing 2
chr5_-_10082244 0.50 ENSDART00000036421
chek2
checkpoint kinase 2
chr11_-_44999858 0.45 ENSDART00000167759
ENSDART00000126845
ldb1b
LIM-domain binding 1b
chr3_+_33745014 0.45 ENSDART00000159966
nacc1a
nucleus accumbens associated 1, BEN and BTB (POZ) domain containing a
chr5_+_33301005 0.44 ENSDART00000006021
usp20
ubiquitin specific peptidase 20
chr12_+_38770654 0.43 ENSDART00000155367
kif19
kinesin family member 19
chr3_+_27770110 0.42 ENSDART00000017962
eci1
enoyl-CoA delta isomerase 1
chr24_+_39277043 0.42 ENSDART00000165458
MPRIP
si:ch73-103b11.2
chr18_+_3634652 0.42 ENSDART00000159913
lrch3
leucine-rich repeats and calponin homology (CH) domain containing 3
chr10_+_22918338 0.41 ENSDART00000167874
ENSDART00000171298
zgc:103508
zgc:103508
chr21_+_37513488 0.41 ENSDART00000185394
amot
angiomotin
chr22_+_29113796 0.41 ENSDART00000150264
pla2g6
phospholipase A2, group VI (cytosolic, calcium-independent)
chr18_+_6641542 0.41 ENSDART00000160379
c2cd5
C2 calcium-dependent domain containing 5
chr12_-_34827477 0.41 ENSDART00000153026
NDUFAF8
si:dkey-21c1.6
chr20_+_6535438 0.40 ENSDART00000145763
si:ch211-191a24.4
si:ch211-191a24.4
chr7_-_26601307 0.40 ENSDART00000188934
plscr3b
phospholipid scramblase 3b
chr3_+_42923275 0.40 ENSDART00000168228
tmem184a
transmembrane protein 184a
chr22_-_14247276 0.40 ENSDART00000033332
si:ch211-246m6.5
si:ch211-246m6.5
chr15_-_28618502 0.39 ENSDART00000086902
slc6a4a
solute carrier family 6 (neurotransmitter transporter), member 4a
chr11_-_44194132 0.39 ENSDART00000182954
ENSDART00000111271
CABZ01080074.1

chr16_-_27149202 0.39 ENSDART00000179726
tmem245
transmembrane protein 245
chr6_-_33685325 0.38 ENSDART00000181883
mast2
microtubule associated serine/threonine kinase 2
chr17_-_15189397 0.37 ENSDART00000133710
ENSDART00000110507
wdhd1
WD repeat and HMG-box DNA binding protein 1
chr2_+_2168547 0.36 ENSDART00000029347
higd1a
HIG1 hypoxia inducible domain family, member 1A
chr1_-_39859626 0.36 ENSDART00000053763
dctd
dCMP deaminase
chr18_-_2222128 0.36 ENSDART00000171402
pigb
phosphatidylinositol glycan anchor biosynthesis, class B
chr7_-_33683891 0.35 ENSDART00000175980
ENSDART00000191148
ENSDART00000173569
tle3b
transducin-like enhancer of split 3b
chr2_+_2967255 0.35 ENSDART00000167649
ENSDART00000166449
pik3r3a
phosphoinositide-3-kinase, regulatory subunit 3a (gamma)
chr24_+_39518774 0.35 ENSDART00000132939
dcun1d3
defective in cullin neddylation 1 domain containing 3
chr24_+_37370064 0.35 ENSDART00000185870
si:ch211-183d21.3
si:ch211-183d21.3
chr21_-_43428040 0.35 ENSDART00000148325
stk26
serine/threonine protein kinase 26
chr4_-_20235904 0.34 ENSDART00000146621
ENSDART00000193655
stk38l
serine/threonine kinase 38 like
chr16_-_25680666 0.34 ENSDART00000132693
ENSDART00000140539
ENSDART00000015302
tomm40
translocase of outer mitochondrial membrane 40 homolog (yeast)
chr7_+_66634167 0.34 ENSDART00000027616
eif4g2a
eukaryotic translation initiation factor 4, gamma 2a
chr17_-_25303486 0.33 ENSDART00000162235
ppie
peptidylprolyl isomerase E (cyclophilin E)
chr16_+_50755133 0.33 ENSDART00000029283
IGLON5
zgc:110372
chr12_-_25097520 0.33 ENSDART00000158036
cript
cysteine-rich PDZ-binding protein
chr12_+_46634736 0.32 ENSDART00000008009
trim16
tripartite motif containing 16
chr5_-_25668787 0.32 ENSDART00000098446
tmc1
transmembrane channel-like 1
chr11_+_31380495 0.32 ENSDART00000185073
sipa1l2
signal-induced proliferation-associated 1 like 2
chr23_+_2714949 0.31 ENSDART00000105284
ncoa6
nuclear receptor coactivator 6
chr10_-_33251876 0.31 ENSDART00000184565
bcl7ba
BCL tumor suppressor 7Ba
chr6_+_32393057 0.31 ENSDART00000190765
dock7
dedicator of cytokinesis 7
chr15_+_25439106 0.31 ENSDART00000156252
aifm4
apoptosis-inducing factor, mitochondrion-associated, 4
chr12_-_31726748 0.31 ENSDART00000153174
srsf2a
serine/arginine-rich splicing factor 2a
chr6_-_1587291 0.30 ENSDART00000067592
ENSDART00000178877
zgc:123305
zgc:123305
chr8_+_9715010 0.30 ENSDART00000139414
gripap1
GRIP1 associated protein 1
chr13_+_7241170 0.30 ENSDART00000109434
aifm2
apoptosis-inducing factor, mitochondrion-associated, 2
chr13_-_25581303 0.29 ENSDART00000087533
csgalnact2
chondroitin sulfate N-acetylgalactosaminyltransferase 2
chr5_-_14509137 0.28 ENSDART00000180742
si:ch211-244o22.2
si:ch211-244o22.2
chr2_-_10564019 0.28 ENSDART00000132167
ccdc18
coiled-coil domain containing 18
chr1_-_46924801 0.27 ENSDART00000142560
pdxkb
pyridoxal (pyridoxine, vitamin B6) kinase b
chr3_+_36646054 0.26 ENSDART00000170013
ENSDART00000159948
gspt1l
G1 to S phase transition 1, like
chr5_+_62611400 0.26 ENSDART00000132054
abr
active BCR-related
chr3_-_40254634 0.26 ENSDART00000154562
top3a
DNA topoisomerase III alpha
chr2_+_34767171 0.26 ENSDART00000145451
astn1
astrotactin 1
chr25_+_20272145 0.26 ENSDART00000109605
si:dkey-219c3.2
si:dkey-219c3.2
chr2_-_22660232 0.26 ENSDART00000174742
thap4
THAP domain containing 4
chr15_+_29728377 0.25 ENSDART00000099958
zgc:153372
zgc:153372
chr5_+_63288599 0.25 ENSDART00000140065
si:ch73-37h15.2
si:ch73-37h15.2
chr1_-_48933 0.25 ENSDART00000171162
ildr1a
immunoglobulin-like domain containing receptor 1a
chr24_-_6024466 0.25 ENSDART00000040865
pdss1
prenyl (decaprenyl) diphosphate synthase, subunit 1
chr19_+_13410903 0.25 ENSDART00000165033
ENSDART00000168672
srsf4
serine/arginine-rich splicing factor 4
chr1_-_23110740 0.25 ENSDART00000171848
ENSDART00000086797
ENSDART00000189344
ENSDART00000190858
adgrl3.1
adhesion G protein-coupled receptor L3.1
chr12_+_21525496 0.24 ENSDART00000152974
ca10a
carbonic anhydrase Xa
chr4_+_9536860 0.24 ENSDART00000130083
lsm8
LSM8 homolog, U6 small nuclear RNA associated
chr2_+_37836821 0.24 ENSDART00000143203
parp2
poly (ADP-ribose) polymerase 2
chr16_-_27138478 0.23 ENSDART00000147438
tmem245
transmembrane protein 245
chr9_-_14683574 0.23 ENSDART00000144022
pard3bb
par-3 family cell polarity regulator beta b
chr25_+_22017182 0.23 ENSDART00000156517
si:dkey-217l24.1
si:dkey-217l24.1
chr23_+_25172682 0.23 ENSDART00000191197
ENSDART00000183497
si:dkey-151g10.3
si:dkey-151g10.3
chr20_+_36806398 0.23 ENSDART00000153317
abracl
ABRA C-terminal like
chr5_+_36896933 0.23 ENSDART00000151984
srsf7a
serine/arginine-rich splicing factor 7a
chr2_+_30787128 0.23 ENSDART00000189233
atp6v1h
ATPase H+ transporting V1 subunit H
chr3_+_46764022 0.23 ENSDART00000023814
prkcsh
protein kinase C substrate 80K-H
chr3_+_31680592 0.23 ENSDART00000172456
mylk5
myosin, light chain kinase 5
chr22_+_17399124 0.23 ENSDART00000145769
rabgap1l
RAB GTPase activating protein 1-like
chr6_+_22068589 0.22 ENSDART00000151205
aldh1l1
aldehyde dehydrogenase 1 family, member L1
chr19_-_3724605 0.22 ENSDART00000123757
smim13
small integral membrane protein 13
chr3_+_50201240 0.22 ENSDART00000156347
epn3a
epsin 3a
chr19_-_7043355 0.21 ENSDART00000104845
tapbp.1
TAP binding protein (tapasin), tandem duplicate 1
chr17_+_12730025 0.21 ENSDART00000064513
il17a/f2
interleukin 17a/f2
chr22_+_2830703 0.21 ENSDART00000145463
ENSDART00000144785
si:dkey-20i20.8
si:dkey-20i20.8
chr5_-_28016805 0.20 ENSDART00000078642
vps37b
vacuolar protein sorting 37 homolog B (S. cerevisiae)
chr23_+_22597624 0.20 ENSDART00000054337
gpr157
G protein-coupled receptor 157
chr22_-_3182965 0.20 ENSDART00000158009
lonp1
lon peptidase 1, mitochondrial
chr22_-_14262115 0.20 ENSDART00000168264
si:ch211-246m6.5
si:ch211-246m6.5
chr23_+_5631381 0.20 ENSDART00000149143
pkp1a
plakophilin 1a
chr15_-_2857961 0.19 ENSDART00000033263
ankrd49
ankyrin repeat domain 49
chr4_-_14470071 0.19 ENSDART00000143773
plxnb2a
plexin b2a
chr16_-_21047872 0.19 ENSDART00000131582
cbx3b
chromobox homolog 3b
chr8_+_10823069 0.19 ENSDART00000081341
mapk13
mitogen-activated protein kinase 13
chr7_+_1467863 0.18 ENSDART00000173433
emc4
ER membrane protein complex subunit 4
chr6_-_11523987 0.18 ENSDART00000189363
gulp1b
GULP, engulfment adaptor PTB domain containing 1b
chr15_+_19324697 0.18 ENSDART00000022015
vps26b
VPS26 retromer complex component B
chr23_-_31693309 0.18 ENSDART00000146327
sgk1
serum/glucocorticoid regulated kinase 1
chr7_-_19638319 0.17 ENSDART00000163686
si:ch211-212k18.4
si:ch211-212k18.4
chr20_+_25879826 0.17 ENSDART00000018519
zgc:153896
zgc:153896
chr19_-_6631900 0.17 ENSDART00000144571
pvrl2l
poliovirus receptor-related 2 like
chr18_-_42333428 0.16 ENSDART00000034225
cntn5
contactin 5
chr13_+_31172833 0.16 ENSDART00000176378
CR931802.3

chr2_-_14387335 0.16 ENSDART00000189332
ENSDART00000164786
ENSDART00000188572
sgip1b
SH3-domain GRB2-like (endophilin) interacting protein 1b
chr5_+_37729207 0.16 ENSDART00000184378
cdc42ep2
CDC42 effector protein (Rho GTPase binding) 2
chr23_+_25172976 0.15 ENSDART00000140789
si:dkey-151g10.3
si:dkey-151g10.3
chr15_+_29727799 0.15 ENSDART00000182006
zgc:153372
zgc:153372
chr20_-_51656512 0.15 ENSDART00000129965
LO018154.1

chr12_+_25223843 0.15 ENSDART00000077180
ENSDART00000127454
ENSDART00000122665
mta3
metastasis associated 1 family, member 3
chr11_+_5880562 0.15 ENSDART00000129663
ENSDART00000130768
ENSDART00000160909
dazap1
DAZ associated protein 1
chr9_+_17423941 0.15 ENSDART00000112884
ENSDART00000155233
kbtbd7
kelch repeat and BTB (POZ) domain containing 7
chr1_+_39859782 0.14 ENSDART00000149984
irf2a
interferon regulatory factor 2a
chr10_+_29199172 0.13 ENSDART00000148828
picalma
phosphatidylinositol binding clathrin assembly protein a
chr3_-_42016693 0.13 ENSDART00000184741
ttyh3a
tweety family member 3a
chr19_-_30404096 0.13 ENSDART00000103475
agr2
anterior gradient 2
chr7_-_33351485 0.13 ENSDART00000146420
anp32a
acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
chr22_+_11153590 0.12 ENSDART00000188207
bcor
BCL6 corepressor
chr8_-_17184482 0.12 ENSDART00000025803
pola2
polymerase (DNA directed), alpha 2
chr21_-_1635268 0.12 ENSDART00000151258
zgc:152948
zgc:152948
chr17_+_31739418 0.12 ENSDART00000155073
ENSDART00000156180
arhgap5
Rho GTPase activating protein 5
chr7_-_72423666 0.12 ENSDART00000191214
rph3ab
rabphilin 3A homolog (mouse), b
chr5_+_24156170 0.12 ENSDART00000136570
slc25a15b
solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15b
chr17_-_27200025 0.12 ENSDART00000192699
asap3
ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
chr25_-_19661198 0.12 ENSDART00000149641
atp2b1b
ATPase plasma membrane Ca2+ transporting 1b
chr7_+_34296789 0.11 ENSDART00000052471
ENSDART00000173798
ENSDART00000173778
bbox1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr1_-_28861226 0.11 ENSDART00000075502
timmdc1
translocase of inner mitochondrial membrane domain containing 1
chr19_+_28187480 0.11 ENSDART00000183825
irx4b
iroquois homeobox 4b
chr17_+_1514711 0.11 ENSDART00000165641
akt1
v-akt murine thymoma viral oncogene homolog 1
chr12_+_30368145 0.11 ENSDART00000153454
ccdc186
si:ch211-225b10.4
chr22_+_20141528 0.10 ENSDART00000187770
eef2a.1
eukaryotic translation elongation factor 2a, tandem duplicate 1
chr22_-_10055744 0.10 ENSDART00000143686
si:ch211-222k6.2
si:ch211-222k6.2
chr7_+_58736889 0.10 ENSDART00000175932
plag1
pleiomorphic adenoma gene 1
chr5_-_41831646 0.10 ENSDART00000134326
si:dkey-65b12.6
si:dkey-65b12.6
chr5_-_55395964 0.10 ENSDART00000145791
prune2
prune homolog 2 (Drosophila)
chr17_-_51224159 0.10 ENSDART00000185749
psen1
presenilin 1
chr12_-_28983584 0.09 ENSDART00000112374
zgc:171713
zgc:171713
chr9_-_44718628 0.09 ENSDART00000059261
dusp19a
dual specificity phosphatase 19a
chr5_+_23201370 0.09 ENSDART00000138123
tpcn1
two pore segment channel 1
chr2_+_52065884 0.09 ENSDART00000146418
shda
Src homology 2 domain containing transforming protein D, a
chr5_+_22677786 0.09 ENSDART00000142112
vma21
VMA21 vacuolar H+-ATPase homolog (S. cerevisiae)
chr11_+_28218141 0.09 ENSDART00000043756
ephb2b
eph receptor B2b
chr14_+_7898372 0.09 ENSDART00000159593
ube2d2
ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast)
chr3_-_18189283 0.08 ENSDART00000049240
tob1a
transducer of ERBB2, 1a
chr19_+_11855330 0.08 ENSDART00000145380
adck5
aarF domain containing kinase 5
chr11_-_28911172 0.08 ENSDART00000168493
igsf21a
immunoglobin superfamily, member 21a
chr4_+_5318901 0.08 ENSDART00000067378
si:ch211-214j24.10
si:ch211-214j24.10
chr7_-_7810348 0.08 ENSDART00000171984
cxcl19
chemokine (C-X-C motif) ligand 19
chr16_-_560574 0.08 ENSDART00000148452
irx2a
iroquois homeobox 2a
chr6_+_7533601 0.07 ENSDART00000057823
pa2g4a
proliferation-associated 2G4, a
chr14_+_36246726 0.07 ENSDART00000105602
elovl6
ELOVL fatty acid elongase 6
chr20_+_49081967 0.07 ENSDART00000112689
crnkl1
crooked neck pre-mRNA splicing factor 1
chr1_-_33556428 0.07 ENSDART00000187346
creb1a
cAMP responsive element binding protein 1a
chr11_-_24510995 0.07 ENSDART00000163489
plekhg5a
pleckstrin homology domain containing, family G (with RhoGef domain) member 5a
chr8_+_22478090 0.07 ENSDART00000170263
si:ch211-261n11.7
si:ch211-261n11.7
chr25_+_6266009 0.07 ENSDART00000148995
slc25a44a
solute carrier family 25, member 44 a
chr5_-_1827575 0.06 ENSDART00000171193
mcc
mutated in colorectal cancers
chr2_-_53592532 0.06 ENSDART00000184066
ccl25a
chemokine (C-C motif) ligand 25a
chr3_+_20012891 0.06 ENSDART00000078974
tmub2
transmembrane and ubiquitin-like domain containing 2
chr7_+_56889879 0.06 ENSDART00000039810
myo9aa
myosin IXAa
chr7_+_22586800 0.06 ENSDART00000035325
chrnb1l
cholinergic receptor, nicotinic, beta 1 (muscle) like
chr5_-_41838354 0.06 ENSDART00000146793
si:dkey-65b12.6
si:dkey-65b12.6
chr8_+_25893071 0.06 ENSDART00000078161
tmem115
transmembrane protein 115
chr3_+_49397115 0.05 ENSDART00000176042
tecra
trans-2,3-enoyl-CoA reductase a
chr1_+_19943803 0.05 ENSDART00000164661
apbb2b
amyloid beta (A4) precursor protein-binding, family B, member 2b
chr19_-_30403922 0.05 ENSDART00000181841
agr2
anterior gradient 2
chr19_-_19599372 0.05 ENSDART00000160002
ENSDART00000171664
tax1bp1a
Tax1 (human T-cell leukemia virus type I) binding protein 1a
chr22_+_15633013 0.05 ENSDART00000188095
ENSDART00000048763
CABZ01090041.1

chr23_-_19953089 0.05 ENSDART00000153828
atp2b3b
ATPase plasma membrane Ca2+ transporting 3b
chr8_+_15251448 0.05 ENSDART00000063717
zgc:171480
zgc:171480
chr18_-_48492951 0.05 ENSDART00000146346
kcnj1a.6
potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 6
chr4_-_27398385 0.05 ENSDART00000142117
ENSDART00000150553
ENSDART00000182746
fam19a5a
family with sequence similarity 19 (chemokine (C-C motif)-like), member A5a
chr18_-_34061477 0.05 ENSDART00000135965
plch1
phospholipase C, eta 1
chr12_-_44122412 0.05 ENSDART00000169094
si:ch73-329n5.3
si:ch73-329n5.3
chr2_+_11028923 0.05 ENSDART00000076725
acot11a
acyl-CoA thioesterase 11a
chr3_+_3454610 0.05 ENSDART00000024900
zgc:165453
zgc:165453
chr16_-_41787421 0.05 ENSDART00000147210
si:dkey-199f5.8
si:dkey-199f5.8
chr7_-_16205471 0.05 ENSDART00000173584
btr05
bloodthirsty-related gene family, member 5
chr14_-_27121854 0.04 ENSDART00000173119
pcdh11
protocadherin 11
chr15_-_25365319 0.04 ENSDART00000152651
cluha
clustered mitochondria (cluA/CLU1) homolog a
chr12_+_34827808 0.04 ENSDART00000105533
tepsin
TEPSIN, adaptor related protein complex 4 accessory protein
chr1_-_21287724 0.04 ENSDART00000193900
npy1r
neuropeptide Y receptor Y1

Network of associatons between targets according to the STRING database.

First level regulatory network of nr4a2a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.1 0.4 GO:0018872 arsonoacetate metabolic process(GO:0018872)
0.1 0.6 GO:0035513 oxidative RNA demethylation(GO:0035513)
0.1 1.0 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.1 0.4 GO:0006837 serotonin transport(GO:0006837) serotonin uptake(GO:0051610)
0.1 0.7 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.1 0.5 GO:0097198 histone H3-K36 trimethylation(GO:0097198)
0.1 0.4 GO:0010828 positive regulation of glucose transport(GO:0010828)
0.1 0.4 GO:0032655 interleukin-12 production(GO:0032615) regulation of interleukin-12 production(GO:0032655)
0.1 0.3 GO:0099563 modification of synaptic structure(GO:0099563)
0.1 0.2 GO:0009256 10-formyltetrahydrofolate metabolic process(GO:0009256) 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
0.1 0.4 GO:0097250 mitochondrial respiratory chain supercomplex assembly(GO:0097250)
0.1 0.2 GO:0051660 establishment of centrosome localization(GO:0051660)
0.1 0.3 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.1 0.4 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.0 0.1 GO:1990575 mitochondrial ornithine transport(GO:0000066) mitochondrial L-ornithine transmembrane transport(GO:1990575)
0.0 0.3 GO:0060005 reflex(GO:0060004) vestibular reflex(GO:0060005)
0.0 0.2 GO:0048069 eye pigmentation(GO:0048069)
0.0 0.7 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.1 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.2 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.0 0.4 GO:0043550 regulation of lipid kinase activity(GO:0043550) regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.0 0.2 GO:0045050 protein insertion into ER membrane by stop-transfer membrane-anchor sequence(GO:0045050)
0.0 0.1 GO:0051563 smooth endoplasmic reticulum calcium ion homeostasis(GO:0051563)
0.0 0.6 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 0.4 GO:0045116 protein neddylation(GO:0045116)
0.0 0.3 GO:0035306 positive regulation of dephosphorylation(GO:0035306) positive regulation of protein dephosphorylation(GO:0035307)
0.0 0.5 GO:0010824 regulation of centrosome duplication(GO:0010824)
0.0 0.1 GO:0072679 thymocyte migration(GO:0072679)
0.0 0.2 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 0.2 GO:0019883 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 0.2 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.0 0.3 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.2 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.0 0.3 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.5 GO:0044773 mitotic DNA damage checkpoint(GO:0044773)
0.0 0.4 GO:0051928 positive regulation of calcium ion transport(GO:0051928)
0.0 0.2 GO:0031272 pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.3 GO:0006265 DNA topological change(GO:0006265)
0.0 0.4 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.3 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.1 GO:0098529 neuromuscular junction development, skeletal muscle fiber(GO:0098529)
0.0 0.2 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.0 0.0 GO:0009211 pyrimidine deoxyribonucleoside triphosphate metabolic process(GO:0009211)
0.0 0.6 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.0 1.1 GO:0090090 negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.0 0.4 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.2 GO:1901663 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.3 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.7 GO:0009062 fatty acid catabolic process(GO:0009062)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0097134 cyclin E1-CDK2 complex(GO:0097134)
0.1 0.4 GO:0016589 NURF complex(GO:0016589)
0.1 0.2 GO:0017177 glucosidase II complex(GO:0017177)
0.1 0.3 GO:0018444 translation release factor complex(GO:0018444)
0.1 0.3 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.0 0.2 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.0 0.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.2 GO:0005688 U6 snRNP(GO:0005688)
0.0 0.1 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.2 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.6 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.5 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.2 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.2 GO:0030904 retromer complex(GO:0030904)
0.0 0.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.6 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 0.0 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) anchored component of the cytoplasmic side of the plasma membrane(GO:0098753)
0.0 0.3 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.4 GO:0032421 stereocilium bundle(GO:0032421)
0.0 0.2 GO:0030057 desmosome(GO:0030057)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.2 0.6 GO:0035516 oxidative DNA demethylase activity(GO:0035516)
0.1 0.4 GO:0030791 arsenite methyltransferase activity(GO:0030791) methylarsonite methyltransferase activity(GO:0030792)
0.1 0.4 GO:0005335 serotonin:sodium symporter activity(GO:0005335) serotonin transmembrane transporter activity(GO:0015222)
0.1 0.7 GO:0015057 thrombin receptor activity(GO:0015057)
0.1 0.2 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.1 0.4 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.1 0.4 GO:0030274 LIM domain binding(GO:0030274)
0.1 0.4 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.0 0.7 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.4 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.7 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.5 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.3 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0 1.2 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.3 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.3 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.0 0.2 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.3 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.7 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.5 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.2 GO:0032977 membrane insertase activity(GO:0032977)
0.0 0.3 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.2 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.0 0.4 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.5 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.1 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.2 GO:0019870 chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.0 0.1 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.6 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.1 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.4 GO:1990939 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) ATP-dependent microtubule motor activity(GO:1990939)
0.0 0.3 GO:0016251 obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.0 0.2 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.1 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.1 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 0.2 GO:0030552 cAMP binding(GO:0030552)
0.0 0.4 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.8 PID ATM PATHWAY ATM pathway
0.0 0.2 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.8 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 1.1 PID E2F PATHWAY E2F transcription factor network
0.0 0.5 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.5 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.4 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 1.3 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.4 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.2 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.2 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.4 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.2 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.3 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.3 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.1 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.2 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.1 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.1 REACTOME SIGNALING BY NOTCH4 Genes involved in Signaling by NOTCH4