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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for nr4a3

Z-value: 0.39

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Transcription factors associated with nr4a3

Gene Symbol Gene ID Gene Info
nr4a3
ENSDARG00000055854 nuclear receptor subfamily 4, group A, member 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nr4a3dr11_v1_chr16_+_27345383_27345383-0.898.3e-07Click!

Activity profile of nr4a3 motif

Sorted Z-values of nr4a3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_17115256 1.29 ENSDART00000190488
pif1
PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)
chr18_-_40708537 1.19 ENSDART00000077577
si:ch211-132b12.8
si:ch211-132b12.8
chr4_-_77116266 1.02 ENSDART00000174249
CU467646.2

chr4_-_77135076 1.00 ENSDART00000174184
zgc:173770
zgc:173770
chr3_+_31662126 0.97 ENSDART00000113441
mylk5
myosin, light chain kinase 5
chr3_+_27770110 0.95 ENSDART00000017962
eci1
enoyl-CoA delta isomerase 1
chr4_-_77130289 0.92 ENSDART00000174380
CU467646.7

chr4_-_77135340 0.90 ENSDART00000180581
ENSDART00000179901
CU467646.7

chr4_-_77120928 0.84 ENSDART00000174154
CU467646.1

chr12_-_33357655 0.78 ENSDART00000066233
ENSDART00000148165
slc16a3
solute carrier family 16 (monocarboxylate transporter), member 3
chr21_+_18405585 0.74 ENSDART00000139318
si:dkey-1d7.3
si:dkey-1d7.3
chr9_+_500052 0.72 ENSDART00000166707
CU984600.1

chr18_+_27515640 0.71 ENSDART00000181593
tp53i11b
tumor protein p53 inducible protein 11b
chr2_-_58075414 0.69 ENSDART00000161920
nectin4
nectin cell adhesion molecule 4
chr8_-_22542467 0.69 ENSDART00000182588
ENSDART00000134542
csde1
cold shock domain containing E1, RNA-binding
chr4_-_4535189 0.69 ENSDART00000057519
zgc:194209
zgc:194209
chr11_+_45287541 0.69 ENSDART00000165321
ENSDART00000173116
pycr1b
pyrroline-5-carboxylate reductase 1b
chr5_+_37406358 0.67 ENSDART00000162811
klhl13
kelch-like family member 13
chr19_-_42045372 0.67 ENSDART00000144275
trioa
trio Rho guanine nucleotide exchange factor a
chr18_+_45571378 0.67 ENSDART00000077251
kifc3
kinesin family member C3
chr3_-_3448095 0.65 ENSDART00000078886
A2ML1 (1 of many)
si:dkey-46g23.5
chr18_+_39416357 0.64 ENSDART00000183174
ENSDART00000127955
ENSDART00000171303
lysmd2
LysM, putative peptidoglycan-binding, domain containing 2
chr10_+_45031398 0.64 ENSDART00000160536
gnsb
glucosamine (N-acetyl)-6-sulfatase (Sanfilippo disease IIID), b
chr12_+_14084291 0.64 ENSDART00000189734
si:ch211-217a12.1
si:ch211-217a12.1
chr3_+_7771420 0.63 ENSDART00000156809
ENSDART00000156309
hook2
hook microtubule-tethering protein 2
chr3_+_3454610 0.60 ENSDART00000024900
zgc:165453
zgc:165453
chr7_-_51775688 0.59 ENSDART00000149793
bmp15
bone morphogenetic protein 15
chr12_+_46634736 0.57 ENSDART00000008009
trim16
tripartite motif containing 16
chr19_-_79202 0.56 ENSDART00000166009
hnrnpr
heterogeneous nuclear ribonucleoprotein R
chr8_-_21110233 0.53 ENSDART00000127371
ENSDART00000100276
tmco1
transmembrane and coiled-coil domains 1
chr16_-_30655980 0.52 ENSDART00000146508
ldlrad4b
low density lipoprotein receptor class A domain containing 4b
chr20_+_36806398 0.51 ENSDART00000153317
abracl
ABRA C-terminal like
chr3_-_34561624 0.51 ENSDART00000129313
sept9a
septin 9a
chr24_-_26820698 0.51 ENSDART00000147788
fndc3bb
fibronectin type III domain containing 3Bb
chr4_-_858434 0.51 ENSDART00000006961
sobpb
sine oculis binding protein homolog (Drosophila) b
chr2_-_4787566 0.50 ENSDART00000160663
ENSDART00000157808
tnk2b
tyrosine kinase, non-receptor, 2b
chr14_+_30413312 0.49 ENSDART00000186864
cnot7
CCR4-NOT transcription complex, subunit 7
chr12_+_23866368 0.49 ENSDART00000188652
ENSDART00000192478
svila
supervillin a
chr1_-_39859626 0.49 ENSDART00000053763
dctd
dCMP deaminase
chr22_-_14262115 0.49 ENSDART00000168264
si:ch211-246m6.5
si:ch211-246m6.5
chr5_-_32489796 0.48 ENSDART00000168870
gpr107
G protein-coupled receptor 107
chr7_+_61764040 0.48 ENSDART00000056745
acox3
acyl-CoA oxidase 3, pristanoyl
chr10_+_20364009 0.47 ENSDART00000186139
ENSDART00000080395
golga7
golgin A7
chr5_-_13076779 0.44 ENSDART00000192826
ypel1
yippee-like 1
chr4_-_9191220 0.44 ENSDART00000156919
hcfc2
host cell factor C2
chr13_+_7241170 0.43 ENSDART00000109434
aifm2
apoptosis-inducing factor, mitochondrion-associated, 2
chr17_-_8592824 0.42 ENSDART00000127022
CU462878.1

chr6_-_31348999 0.40 ENSDART00000153734
dnajc6
DnaJ (Hsp40) homolog, subfamily C, member 6
chr7_+_41887429 0.40 ENSDART00000115090
gpt2
glutamic pyruvate transaminase (alanine aminotransferase) 2
chr6_+_30533504 0.40 ENSDART00000155842
wwc3
WWC family member 3
chr5_+_29831235 0.40 ENSDART00000109660
f11r.1
F11 receptor, tandem duplicate 1
chr23_-_27050083 0.39 ENSDART00000142324
ENSDART00000133249
ENSDART00000138751
ENSDART00000128718
zgc:66440
zgc:66440
chr25_+_22017182 0.39 ENSDART00000156517
si:dkey-217l24.1
si:dkey-217l24.1
chr15_+_40188076 0.39 ENSDART00000063779
efhd1
EF-hand domain family, member D1
chr20_+_6535438 0.38 ENSDART00000145763
si:ch211-191a24.4
si:ch211-191a24.4
chr2_+_44977889 0.37 ENSDART00000144024
alg3
asparagine-linked glycosylation 3 (alpha-1,3-mannosyltransferase)
chr19_-_24136233 0.36 ENSDART00000143365
thap7
THAP domain containing 7
chr17_-_25303486 0.36 ENSDART00000162235
ppie
peptidylprolyl isomerase E (cyclophilin E)
chr23_+_25172682 0.36 ENSDART00000191197
ENSDART00000183497
si:dkey-151g10.3
si:dkey-151g10.3
chr2_+_30249977 0.36 ENSDART00000109160
ENSDART00000135171
tmem70
transmembrane protein 70
chr16_-_19568795 0.35 ENSDART00000185141
abcb5
ATP-binding cassette, sub-family B (MDR/TAP), member 5
chr12_-_34827477 0.35 ENSDART00000153026
NDUFAF8
si:dkey-21c1.6
chr1_+_24469313 0.35 ENSDART00000176581
fam160a1a
family with sequence similarity 160, member A1a
chr11_-_44999858 0.34 ENSDART00000167759
ENSDART00000126845
ldb1b
LIM-domain binding 1b
chr3_+_23047241 0.34 ENSDART00000103858
b4galnt2.2
beta-1,4-N-acetyl-galactosaminyl transferase 2, tandem duplicate 2
chr3_+_35611625 0.34 ENSDART00000190995
traf7
TNF receptor-associated factor 7
chr10_+_36441124 0.33 ENSDART00000185626
uspl1
ubiquitin specific peptidase like 1
chr25_+_418932 0.33 ENSDART00000059193
prtgb
protogenin homolog b (Gallus gallus)
chr7_-_42206720 0.33 ENSDART00000110907
itfg1
integrin alpha FG-GAP repeat containing 1
chr9_-_44905867 0.33 ENSDART00000138316
ENSDART00000131252
ENSDART00000179383
ENSDART00000159337
zgc:66484
zgc:66484
chr6_-_1587291 0.33 ENSDART00000067592
ENSDART00000178877
zgc:123305
zgc:123305
chr6_+_40952031 0.33 ENSDART00000189219
patz1
POZ (BTB) and AT hook containing zinc finger 1
chr23_-_24247672 0.32 ENSDART00000141552
zbtb17
zinc finger and BTB domain containing 17
chr14_+_30413758 0.32 ENSDART00000092953
cnot7
CCR4-NOT transcription complex, subunit 7
chr15_-_16946124 0.32 ENSDART00000154923
hip1
huntingtin interacting protein 1
chr17_-_27200025 0.31 ENSDART00000192699
asap3
ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
chr20_-_44575103 0.31 ENSDART00000192573
ubxn2a
UBX domain protein 2A
chr5_+_36896933 0.31 ENSDART00000151984
srsf7a
serine/arginine-rich splicing factor 7a
chr4_-_2975461 0.31 ENSDART00000150794
plekha5
pleckstrin homology domain containing, family A member 5
chr6_-_15065376 0.31 ENSDART00000087797
tgfbrap1
transforming growth factor, beta receptor associated protein 1
chr19_-_47997424 0.31 ENSDART00000081675
ctnnb2
catenin, beta 2
chr25_-_9805269 0.31 ENSDART00000192048
lrrc4c
leucine rich repeat containing 4C
chr19_+_20787179 0.30 ENSDART00000193204
adnp2b
ADNP homeobox 2b
chr12_+_45238292 0.30 ENSDART00000057983
mrpl38
mitochondrial ribosomal protein L38
chr21_-_43398457 0.30 ENSDART00000166530
ccni2
cyclin I family, member 2
chr20_+_6535176 0.29 ENSDART00000054652
si:ch211-191a24.4
si:ch211-191a24.4
chr2_-_7246848 0.29 ENSDART00000146434
zgc:153115
zgc:153115
chr16_+_20871021 0.28 ENSDART00000006429
hibadhb
3-hydroxyisobutyrate dehydrogenase b
chr5_-_69923241 0.28 ENSDART00000187389
fktn
fukutin
chr3_-_27868183 0.27 ENSDART00000185812
abat
4-aminobutyrate aminotransferase
chr23_+_39346774 0.26 ENSDART00000190985
src
v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
chr14_-_33265068 0.26 ENSDART00000147038
gdpd2
glycerophosphodiester phosphodiesterase domain containing 2
chr1_-_53625142 0.26 ENSDART00000166852
USP34
ubiquitin specific peptidase 34
chr9_-_21825913 0.25 ENSDART00000101986
mrpl30
mitochondrial ribosomal protein L30
chr1_+_39859782 0.25 ENSDART00000149984
irf2a
interferon regulatory factor 2a
chr5_+_69650148 0.25 ENSDART00000097244
gtf2h3
general transcription factor IIH, polypeptide 3
chr3_-_18189283 0.24 ENSDART00000049240
tob1a
transducer of ERBB2, 1a
chr10_+_24692076 0.24 ENSDART00000181600
tpte
transmembrane phosphatase with tensin homology
chr15_+_47618221 0.24 ENSDART00000168722
paf1
PAF1 homolog, Paf1/RNA polymerase II complex component
chr10_+_8875195 0.24 ENSDART00000141045
itga2.3
integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor), tandem duplicate 3
chr21_+_1119046 0.24 ENSDART00000184678
CABZ01088049.1

chr8_-_52909850 0.24 ENSDART00000161943
nr6a1a
nuclear receptor subfamily 6, group A, member 1a
chr3_-_5829501 0.23 ENSDART00000091017
pkn1b
protein kinase N1b
chr3_-_18373425 0.23 ENSDART00000178522
spag9a
sperm associated antigen 9a
chr10_-_41400049 0.23 ENSDART00000009838
gpat4
glycerol-3-phosphate acyltransferase 4
chr2_-_31700396 0.23 ENSDART00000142366
lrrcc1
leucine rich repeat and coiled-coil centrosomal protein 1
chr5_-_17876709 0.23 ENSDART00000141978
si:dkey-112e17.1
si:dkey-112e17.1
chr9_-_7212973 0.23 ENSDART00000133638
mgat4a
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr5_-_14509137 0.23 ENSDART00000180742
si:ch211-244o22.2
si:ch211-244o22.2
chr3_-_37351225 0.22 ENSDART00000174685
si:ch211-278a6.1
si:ch211-278a6.1
chr2_+_34767171 0.22 ENSDART00000145451
astn1
astrotactin 1
chr17_+_654759 0.22 ENSDART00000193703
CABZ01079748.1

chr13_-_49666615 0.22 ENSDART00000148083
tomm20a
translocase of outer mitochondrial membrane 20
chr6_+_7414215 0.21 ENSDART00000049339
sox21a
SRY (sex determining region Y)-box 21a
chr2_+_26060528 0.21 ENSDART00000058111
grin3ba
glutamate receptor, ionotropic, N-methyl-D-aspartate 3Ba
chr16_-_20870143 0.21 ENSDART00000169541
ENSDART00000040727
tax1bp1b
Tax1 (human T-cell leukemia virus type I) binding protein 1b
chr23_+_39346930 0.21 ENSDART00000102843
src
v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
chr19_-_17972734 0.21 ENSDART00000126298
ints8
integrator complex subunit 8
chr7_+_42206847 0.21 ENSDART00000149250
phkb
phosphorylase kinase, beta
chr11_-_40647190 0.20 ENSDART00000173217
ENSDART00000173276
ENSDART00000147264
fam213b
family with sequence similarity 213, member B
chr9_+_8761099 0.20 ENSDART00000159077
col4a2
collagen, type IV, alpha 2
chr10_-_26202766 0.20 ENSDART00000136393
fhdc3
FH2 domain containing 3
chr22_+_29113796 0.20 ENSDART00000150264
pla2g6
phospholipase A2, group VI (cytosolic, calcium-independent)
chr1_+_24557414 0.20 ENSDART00000076519
dctpp1
dCTP pyrophosphatase 1
chr16_+_52343905 0.20 ENSDART00000131051
ifnlr1
interferon lambda receptor 1
chr8_-_21091961 0.20 ENSDART00000100281
aldh9a1a.2
aldehyde dehydrogenase 9 family, member A1a, tandem duplicate 2
chr2_-_8102169 0.19 ENSDART00000131955
pls1
plastin 1 (I isoform)
chr15_+_32405959 0.19 ENSDART00000177269
si:ch211-162k9.6
si:ch211-162k9.6
chr2_-_41562868 0.19 ENSDART00000084597
d2hgdh
D-2-hydroxyglutarate dehydrogenase
chr22_+_17399124 0.19 ENSDART00000145769
rabgap1l
RAB GTPase activating protein 1-like
chr2_+_50722439 0.18 ENSDART00000188927
fyco1b
FYVE and coiled-coil domain containing 1b
chr7_+_38267136 0.18 ENSDART00000173613
gpatch1
G patch domain containing 1
chr22_-_7050 0.17 ENSDART00000127829
atad3
ATPase family, AAA domain containing 3
chr1_-_51720633 0.17 ENSDART00000045894
rnaseh2a
ribonuclease H2, subunit A
chr7_+_20876303 0.17 ENSDART00000173495
ENSDART00000164172
gigyf1a
GRB10 interacting GYF protein 1a
chr1_-_28861226 0.17 ENSDART00000075502
timmdc1
translocase of inner mitochondrial membrane domain containing 1
chr4_+_77957611 0.16 ENSDART00000156692
arfgap3
ADP-ribosylation factor GTPase activating protein 3
chr23_+_44614056 0.16 ENSDART00000188379
eno3
enolase 3, (beta, muscle)
chr15_-_25365570 0.16 ENSDART00000152754
cluha
clustered mitochondria (cluA/CLU1) homolog a
chr2_+_37110504 0.16 ENSDART00000132794
ENSDART00000042974
slc1a8b
solute carrier family 1 (glutamate transporter), member 8b
chr25_-_35095129 0.15 ENSDART00000099866
ENSDART00000099868
kif15
kinesin family member 15
chr7_+_24520518 0.15 ENSDART00000173604
btr09
bloodthirsty-related gene family, member 9
chr12_+_46791907 0.15 ENSDART00000110304
vcla
vinculin a
chr7_+_22586800 0.14 ENSDART00000035325
chrnb1l
cholinergic receptor, nicotinic, beta 1 (muscle) like
chr24_+_81527 0.14 ENSDART00000192139
reck
reversion-inducing-cysteine-rich protein with kazal motifs
chr1_+_38153944 0.14 ENSDART00000135666
galnt7
UDP-N-acetyl-alpha-D-galactosamine: polypeptide N-acetylgalactosaminyltransferase 7
chr20_+_37794633 0.13 ENSDART00000022060
atf3
activating transcription factor 3
chr2_-_56649883 0.13 ENSDART00000191786
gpx4b
glutathione peroxidase 4b
chr18_+_44769027 0.13 ENSDART00000145190
ilvbl
ilvB (bacterial acetolactate synthase)-like
chr3_-_58455289 0.13 ENSDART00000052179
cdr2a
cerebellar degeneration-related protein 2a
chr23_-_46126444 0.13 ENSDART00000030004
CABZ01071903.1

chr1_-_55196103 0.13 ENSDART00000140153
mri1
methylthioribose-1-phosphate isomerase 1
chr5_+_24156170 0.12 ENSDART00000136570
slc25a15b
solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15b
chr24_+_39034090 0.12 ENSDART00000185763
capn15
calpain 15
chr13_-_30143127 0.12 ENSDART00000146097
tysnd1
trypsin domain containing 1
chr25_+_35663933 0.12 ENSDART00000154979
slc2a13b
solute carrier family 2 (facilitated glucose transporter), member 13b
chr21_-_1640547 0.11 ENSDART00000151041
zgc:152948
zgc:152948
chr17_+_48314724 0.11 ENSDART00000125617
smoc1
SPARC related modular calcium binding 1
chr14_+_20941534 0.11 ENSDART00000185616
zgc:66433
zgc:66433
chr12_+_34827808 0.11 ENSDART00000105533
tepsin
TEPSIN, adaptor related protein complex 4 accessory protein
chr7_+_1442059 0.11 ENSDART00000173391
si:cabz01090193.1
si:cabz01090193.1
chr22_-_31020690 0.11 ENSDART00000130604
ssuh2.4
ssu-2 homolog, tandem duplicate 4
chr7_+_50766094 0.11 ENSDART00000165037
si:ch73-380l10.2
si:ch73-380l10.2
chr5_-_45634675 0.10 ENSDART00000168534
NPFFR2
neuropeptide FF receptor 2a
chr17_+_1514711 0.10 ENSDART00000165641
akt1
v-akt murine thymoma viral oncogene homolog 1
chr13_-_3879254 0.10 ENSDART00000166427
ENSDART00000171033
si:ch211-128m15.3
si:ch211-128m15.3
chr8_-_27849770 0.09 ENSDART00000190196
ENSDART00000181244
cttnbp2nlb
CTTNBP2 N-terminal like b
chr3_+_57825938 0.09 ENSDART00000128815
cenpx
centromere protein X
chr15_+_45994123 0.09 ENSDART00000124704
lrfn1
leucine rich repeat and fibronectin type III domain containing 1
chr8_-_40183197 0.09 ENSDART00000005118
gpx8
glutathione peroxidase 8 (putative)
chr7_+_65398161 0.08 ENSDART00000166109
ENSDART00000157399
usp47
ubiquitin specific peptidase 47
chr20_+_25575391 0.08 ENSDART00000063108
cyp2p8
cytochrome P450, family 2, subfamily P, polypeptide 8
chr9_+_17429170 0.08 ENSDART00000006256
zgc:101559
zgc:101559
chr21_-_15200556 0.08 ENSDART00000141809
sfswap
splicing factor SWAP
chr15_-_16884912 0.08 ENSDART00000062135
zgc:103681
zgc:103681
chr13_-_25719628 0.08 ENSDART00000135383
si:dkey-192p21.6
si:dkey-192p21.6
chr7_+_34296789 0.07 ENSDART00000052471
ENSDART00000173798
ENSDART00000173778
bbox1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr19_+_2631565 0.07 ENSDART00000171487
fam126a
family with sequence similarity 126, member A
chr10_-_36223005 0.07 ENSDART00000159962
or109-6
odorant receptor, family D, subfamily 109, member 6
chr23_-_20154422 0.07 ENSDART00000132025
usp19
ubiquitin specific peptidase 19
chr11_-_7411436 0.07 ENSDART00000167312
adgrl4
adhesion G protein-coupled receptor L4
chr7_-_32021853 0.07 ENSDART00000134521
kif18a
kinesin family member 18A
chr8_+_1170015 0.07 ENSDART00000081457
ENSDART00000164116
ccl27a
chemokine (C-C motif) ligand 27a
chr25_-_31898552 0.07 ENSDART00000156128
si:ch73-330k17.3
si:ch73-330k17.3
chr24_+_25467465 0.07 ENSDART00000189933
smpx
small muscle protein, X-linked
chr8_+_22478090 0.07 ENSDART00000170263
si:ch211-261n11.7
si:ch211-261n11.7
chr13_-_28263856 0.07 ENSDART00000041036
ENSDART00000079806
smap1
small ArfGAP 1
chr3_-_7129057 0.06 ENSDART00000125947
BX005085.1

chr6_-_35439406 0.06 ENSDART00000073784
rgs5a
regulator of G protein signaling 5a
chr22_-_6361178 0.06 ENSDART00000150147
zgc:113298
zgc:113298
chr13_-_214122 0.06 ENSDART00000169273
ppp1r21
protein phosphatase 1, regulatory subunit 21
chr5_+_52167986 0.06 ENSDART00000162256
ENSDART00000073626
slc14a2
solute carrier family 14 (urea transporter), member 2
chr25_-_10622449 0.06 ENSDART00000155375
ppp6r3
protein phosphatase 6, regulatory subunit 3
chr8_+_6954984 0.06 ENSDART00000145610
si:ch211-255g12.6
si:ch211-255g12.6
chr16_+_17252487 0.06 ENSDART00000063572
gtf3c6
general transcription factor IIIC, polypeptide 6, alpha
chr7_+_73649686 0.06 ENSDART00000185589
PCP4L1
si:dkey-46i9.1
chr25_+_7591293 0.06 ENSDART00000130416
FO704779.1

chr18_+_34478959 0.06 ENSDART00000059394
kcnab1a
potassium voltage-gated channel, shaker-related subfamily, beta member 1 a
chr1_-_57172294 0.05 ENSDART00000063774
rac1l
Rac family small GTPase 1, like
chr24_+_35183595 0.05 ENSDART00000075142
pcmtd1
protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1

Network of associatons between targets according to the STRING database.

First level regulatory network of nr4a3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0009162 deoxyribonucleoside monophosphate metabolic process(GO:0009162)
0.2 0.5 GO:0050847 progesterone receptor signaling pathway(GO:0050847)
0.1 0.6 GO:0060283 negative regulation of oocyte development(GO:0060283)
0.1 0.5 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.1 0.4 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.1 0.3 GO:0046689 response to mercury ion(GO:0046689) detoxification of mercury ion(GO:0050787)
0.1 1.3 GO:0000002 mitochondrial genome maintenance(GO:0000002)
0.1 0.3 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1 0.4 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.1 0.5 GO:0032469 endoplasmic reticulum calcium ion homeostasis(GO:0032469)
0.1 0.5 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1 0.8 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.1 0.3 GO:1903405 nuclear body organization(GO:0030575) Cajal body organization(GO:0030576) protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) protein localization to nucleoplasm(GO:1990173)
0.1 0.2 GO:0009211 pyrimidine deoxyribonucleoside triphosphate metabolic process(GO:0009211)
0.1 0.3 GO:0060049 regulation of protein glycosylation(GO:0060049)
0.1 0.2 GO:0048205 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.1 0.3 GO:0009450 gamma-aminobutyric acid catabolic process(GO:0009450)
0.0 0.1 GO:1905048 regulation of metallopeptidase activity(GO:1905048)
0.0 0.1 GO:0019284 L-methionine biosynthetic process from S-adenosylmethionine(GO:0019284)
0.0 0.1 GO:0000066 mitochondrial ornithine transport(GO:0000066) mitochondrial L-ornithine transmembrane transport(GO:1990575)
0.0 0.3 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.2 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.0 0.1 GO:0071470 cellular response to osmotic stress(GO:0071470)
0.0 0.2 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.0 0.1 GO:0006549 isoleucine metabolic process(GO:0006549) isoleucine biosynthetic process(GO:0009097)
0.0 1.1 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.0 0.4 GO:0050892 intestinal absorption(GO:0050892)
0.0 0.5 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.0 0.3 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.0 0.1 GO:0086013 membrane repolarization during cardiac muscle cell action potential(GO:0086013)
0.0 0.4 GO:2000651 positive regulation of sodium ion transport(GO:0010765) positive regulation of potassium ion transport(GO:0043268) positive regulation of potassium ion transmembrane transport(GO:1901381) positive regulation of sodium ion transmembrane transport(GO:1902307) regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288) positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.0 0.2 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.0 0.2 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.2 GO:0035306 positive regulation of dephosphorylation(GO:0035306) positive regulation of protein dephosphorylation(GO:0035307)
0.0 0.3 GO:2000404 regulation of T cell migration(GO:2000404)
0.0 0.2 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 0.2 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 0.5 GO:0051014 actin filament severing(GO:0051014)
0.0 0.2 GO:0061001 regulation of dendritic spine morphogenesis(GO:0061001)
0.0 0.1 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.4 GO:0008637 apoptotic mitochondrial changes(GO:0008637)
0.0 0.1 GO:1901380 negative regulation of potassium ion transmembrane transporter activity(GO:1901017) negative regulation of potassium ion transmembrane transport(GO:1901380) negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.0 0.1 GO:0055129 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.0 0.1 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.3 GO:0009062 fatty acid catabolic process(GO:0009062)
0.0 0.2 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.4 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.2 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 0.0 GO:0071918 urea transmembrane transport(GO:0071918)
0.0 0.3 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.6 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 0.3 GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0006919)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0098890 extrinsic component of postsynaptic membrane(GO:0098890)
0.1 0.8 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.1 0.2 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.1 GO:0005948 acetolactate synthase complex(GO:0005948)
0.0 0.2 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 0.2 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.1 GO:1990909 Wnt signalosome(GO:1990909)
0.0 0.5 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.0 1.3 GO:0005657 replication fork(GO:0005657)
0.0 0.2 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.2 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.3 GO:0015030 Cajal body(GO:0015030)
0.0 0.1 GO:0061673 mitotic spindle astral microtubule(GO:0061673)
0.0 0.2 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.4 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.1 GO:0043034 costamere(GO:0043034)
0.0 0.5 GO:0032156 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.1 GO:0005892 acetylcholine-gated channel complex(GO:0005892)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.1 1.0 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.1 0.5 GO:0070412 R-SMAD binding(GO:0070412)
0.1 0.5 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.1 0.4 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.1 0.6 GO:0070698 type I activin receptor binding(GO:0070698)
0.1 1.0 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 0.3 GO:0032183 SUMO binding(GO:0032183)
0.1 0.3 GO:0046592 polyamine oxidase activity(GO:0046592)
0.1 0.8 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 0.7 GO:0016840 carbon-nitrogen lyase activity(GO:0016840)
0.1 0.8 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.3 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.2 GO:0047105 aminobutyraldehyde dehydrogenase activity(GO:0019145) 4-trimethylammoniobutyraldehyde dehydrogenase activity(GO:0047105)
0.0 0.2 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.1 GO:0003984 acetolactate synthase activity(GO:0003984)
0.0 0.2 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0 0.3 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.6 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.6 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.3 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.2 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0 0.3 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.1 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 0.2 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.4 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.4 GO:0019869 chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.0 0.2 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 1.3 GO:0030170 pyridoxal phosphate binding(GO:0030170)
0.0 0.1 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.5 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.1 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.1 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.9 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.1 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.5 GO:0019239 deaminase activity(GO:0019239)
0.0 0.1 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.2 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.5 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 ST STAT3 PATHWAY STAT3 Pathway
0.0 1.2 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 1.0 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.3 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.7 PID AURORA B PATHWAY Aurora B signaling
0.0 0.7 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 0.5 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 0.8 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.4 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.8 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 0.5 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.5 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.3 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 0.1 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.7 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.4 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.2 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.3 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.2 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.2 REACTOME KINESINS Genes involved in Kinesins