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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for nr5a1a+nr5a2+nr5a5

Z-value: 1.04

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Transcription factors associated with nr5a1a+nr5a2+nr5a5

Gene Symbol Gene ID Gene Info
nr5a5
ENSDARG00000039116 nuclear receptor subfamily 5, group A, member 5
nr5a2
ENSDARG00000100940 nuclear receptor subfamily 5, group A, member 2
nr5a1a
ENSDARG00000103176 nuclear receptor subfamily 5, group A, member 1a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nr5a1adr11_v1_chr8_-_52871056_528710560.897.7e-07Click!
nr5a2dr11_v1_chr22_-_22719440_227194400.643.9e-03Click!
nr5a5dr11_v1_chr3_-_53465223_534652490.513.0e-02Click!

Activity profile of nr5a1a+nr5a2+nr5a5 motif

Sorted Z-values of nr5a1a+nr5a2+nr5a5 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_24488652 5.31 ENSDART00000052067
insl3
insulin-like 3 (Leydig cell)
chr13_+_50375800 4.45 ENSDART00000099537
cox5b2
cytochrome c oxidase subunit Vb 2
chr21_+_198269 3.73 ENSDART00000193485
ENSDART00000163696
gsdf
gonadal somatic cell derived factor
chr15_-_20916251 3.40 ENSDART00000134053
usp2a
ubiquitin specific peptidase 2a
chr7_-_59256806 2.98 ENSDART00000167955
m1ap
meiosis 1 associated protein
chr16_+_52512025 2.96 ENSDART00000056095
fabp10a
fatty acid binding protein 10a, liver basic
chr8_-_36554675 2.93 ENSDART00000132804
ENSDART00000078746
ccdc157
coiled-coil domain containing 157
chr19_-_12145765 2.85 ENSDART00000032474
pabpc1b
poly A binding protein, cytoplasmic 1 b
chr22_+_7439476 2.78 ENSDART00000021594
ENSDART00000063389
zgc:92041
zgc:92041
chr9_+_21194445 2.61 ENSDART00000061321
hsd3b1
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
chr19_-_12145390 2.56 ENSDART00000143087
pabpc1b
poly A binding protein, cytoplasmic 1 b
chr22_-_2886937 2.41 ENSDART00000063533
aqp12
aquaporin 12
chr21_+_17956856 2.40 ENSDART00000080431
dnai1.2
dynein, axonemal, intermediate chain 1, paralog 2
chr8_-_21372446 2.32 ENSDART00000061481
ENSDART00000079293
ela2l
elastase 2 like
chr16_-_25085327 2.32 ENSDART00000077661
prss1
protease, serine 1
chr23_+_27345826 2.31 ENSDART00000132635
tmprss12
transmembrane (C-terminal) protease, serine 12
chr8_-_48770603 2.19 ENSDART00000159712
pimr184
Pim proto-oncogene, serine/threonine kinase, related 184
chr5_+_20693724 2.18 ENSDART00000141368
si:ch211-240b21.2
si:ch211-240b21.2
chr2_+_17508323 2.17 ENSDART00000169703
pimr199
Pim proto-oncogene, serine/threonine kinase, related 199
chr10_+_25355308 2.17 ENSDART00000100415
map3k7cl
map3k7 C-terminal like
chr14_-_36397768 2.14 ENSDART00000185199
ENSDART00000052562
spata4
spermatogenesis associated 4
chr12_+_45200744 1.97 ENSDART00000098932
wbp2
WW domain binding protein 2
chr6_-_21091948 1.96 ENSDART00000057348
inha
inhibin, alpha
chr22_-_20761759 1.93 ENSDART00000013803
amh
anti-Mullerian hormone
chr18_-_44285539 1.90 ENSDART00000137222
pimr179
Pim proto-oncogene, serine/threonine kinase, related 179
chr3_-_52674089 1.87 ENSDART00000154260
ENSDART00000125455
si:dkey-210j14.4
si:dkey-210j14.4
chr6_+_7250824 1.87 ENSDART00000177226
dzip1
DAZ interacting zinc finger protein 1
chr22_+_7480465 1.80 ENSDART00000034545
CELA1 (1 of many)
zgc:92745
chr22_-_36934040 1.78 ENSDART00000151666
pimr206
Pim proto-oncogene, serine/threonine kinase, related 206
chr7_+_34688527 1.78 ENSDART00000108473
plekhg4
pleckstrin homology domain containing, family G (with RhoGef domain) member 4
chr5_-_42544522 1.76 ENSDART00000157968
BX510949.1

chr8_-_29719393 1.76 ENSDART00000077635
si:ch211-103n10.5
si:ch211-103n10.5
chr18_-_24996634 1.72 ENSDART00000170210
si:ch211-196l7.4
si:ch211-196l7.4
chr11_-_8226088 1.66 ENSDART00000173364
si:cabz01021067.1
si:cabz01021067.1
chr25_+_3326885 1.66 ENSDART00000104866
ldhbb
lactate dehydrogenase Bb
chr3_-_1434135 1.65 ENSDART00000149622
mgp
matrix Gla protein
chr11_-_8271374 1.63 ENSDART00000168253
pimr202
Pim proto-oncogene, serine/threonine kinase, related 202
chr1_+_54911458 1.62 ENSDART00000089603
golga7ba
golgin A7 family, member Ba
chrM_+_9735 1.60 ENSDART00000093613
mt-co3
cytochrome c oxidase III, mitochondrial
chr20_+_54738210 1.60 ENSDART00000151399
pak7
p21 protein (Cdc42/Rac)-activated kinase 7
chr1_+_9994811 1.59 ENSDART00000143719
ENSDART00000110749
si:dkeyp-75b4.10
si:dkeyp-75b4.10
chr10_-_27197044 1.57 ENSDART00000137928
auts2a
autism susceptibility candidate 2a
chr14_+_45732081 1.57 ENSDART00000110103
ccdc88b
coiled-coil domain containing 88B
chr11_+_25472758 1.56 ENSDART00000011178
opn1sw2
opsin 1 (cone pigments), short-wave-sensitive 2
chr13_-_44738574 1.55 ENSDART00000074761
zfand3
zinc finger, AN1-type domain 3
chr25_+_27873836 1.52 ENSDART00000163801
iqub
IQ motif and ubiquitin domain containing
chr11_+_25259058 1.51 ENSDART00000154109
tp53inp2
tumor protein p53 inducible nuclear protein 2
chr3_+_1182315 1.49 ENSDART00000055430
ndufa6
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6
chr10_-_16065185 1.48 ENSDART00000187266
si:dkey-184a18.5
si:dkey-184a18.5
chr7_-_28148310 1.45 ENSDART00000044208
lmo1
LIM domain only 1
chr12_-_30583668 1.38 ENSDART00000153406
casp7
caspase 7, apoptosis-related cysteine peptidase
chr6_-_43922813 1.37 ENSDART00000123341
prok2
prokineticin 2
chr7_-_28549361 1.37 ENSDART00000173918
ENSDART00000054368
ENSDART00000113313
st5
suppression of tumorigenicity 5
chr7_-_24204665 1.35 ENSDART00000167141
gmpr2
guanosine monophosphate reductase 2
chr11_-_8288925 1.33 ENSDART00000168524
pimr202
Pim proto-oncogene, serine/threonine kinase, related 202
chr3_+_26081343 1.33 ENSDART00000134647
atp2a1
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1
chr22_+_7439186 1.33 ENSDART00000190667
zgc:92041
zgc:92041
chr9_+_17348745 1.29 ENSDART00000147488
slain1a
SLAIN motif family, member 1a
chr13_-_2215213 1.26 ENSDART00000129773
mlip
muscular LMNA-interacting protein
chr24_+_22021675 1.24 ENSDART00000081234
ropn1l
rhophilin associated tail protein 1-like
chr7_+_19904136 1.22 ENSDART00000173452
si:ch211-285j22.3
si:ch211-285j22.3
chr6_-_49078263 1.21 ENSDART00000032982
slc5a8l
solute carrier family 5 (iodide transporter), member 8-like
chr25_+_3327071 1.19 ENSDART00000136131
ENSDART00000133243
ldhbb
lactate dehydrogenase Bb
chr4_-_9764767 1.18 ENSDART00000164328
ENSDART00000147699
mical3b
microtubule associated monooxygenase, calponin and LIM domain containing 3b
chr17_-_12385308 1.15 ENSDART00000080927
snap25b
synaptosomal-associated protein, 25b
chr7_-_24204200 1.14 ENSDART00000087298
gmpr2
guanosine monophosphate reductase 2
chr21_+_30355767 1.12 ENSDART00000189948
CR749164.1

chr3_+_39568290 1.08 ENSDART00000020741
aldoaa
aldolase a, fructose-bisphosphate, a
chr7_+_568819 1.07 ENSDART00000173716
nrxn2b
neurexin 2b
chr20_+_218886 1.07 ENSDART00000002661
lama4
laminin, alpha 4
chr25_+_245018 1.07 ENSDART00000155344
zgc:92481
zgc:92481
chr12_-_48477031 1.05 ENSDART00000105176
ndufb8
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8
chr19_+_619200 1.04 ENSDART00000050125
nupl2
nucleoporin like 2
chr8_-_52715911 1.03 ENSDART00000168241
tubb2b
tubulin, beta 2b
chr20_+_35086242 1.03 ENSDART00000114262
cdc42bpab
CDC42 binding protein kinase alpha (DMPK-like) b
chr12_+_24738962 1.01 ENSDART00000105751
fshr
follicle stimulating hormone receptor
chr2_-_20599315 1.01 ENSDART00000114199
si:ch211-267e7.3
si:ch211-267e7.3
chr7_+_20475788 1.01 ENSDART00000171155
si:dkey-19b23.13
si:dkey-19b23.13
chr7_+_20467549 1.01 ENSDART00000173724
si:dkey-33c9.8
si:dkey-33c9.8
chr1_+_52735484 1.00 ENSDART00000182076
CABZ01021532.1

chr22_+_7472420 1.00 ENSDART00000132049
CELA1 (1 of many)
si:dkey-57c15.4
chr15_+_20403903 0.99 ENSDART00000134182
cox7a1
cytochrome c oxidase subunit VIIa polypeptide 1 (muscle)
chr11_-_10770053 0.98 ENSDART00000179213
slc4a10a
solute carrier family 4, sodium bicarbonate transporter, member 10a
chr5_-_32445835 0.97 ENSDART00000170919
ncs1a
neuronal calcium sensor 1a
chr22_-_34551568 0.97 ENSDART00000148147
rnf123
ring finger protein 123
chr12_+_7865470 0.96 ENSDART00000161683
BX548028.1

chr8_+_23213320 0.95 ENSDART00000032996
ENSDART00000137536
ppdpfa
pancreatic progenitor cell differentiation and proliferation factor a
chr13_-_6218248 0.95 ENSDART00000159052
si:zfos-1056e6.1
si:zfos-1056e6.1
chr14_+_35892802 0.95 ENSDART00000135079
zgc:63568
zgc:63568
chr1_+_580642 0.93 ENSDART00000147633
mrpl39
mitochondrial ribosomal protein L39
chr5_-_36328688 0.93 ENSDART00000011399
efnb1
ephrin-B1
chr18_+_14529005 0.92 ENSDART00000186379
kcng4a
potassium voltage-gated channel, subfamily G, member 4a
chr19_+_24488403 0.92 ENSDART00000052421
txnipa
thioredoxin interacting protein a
chr14_-_5678457 0.88 ENSDART00000012116
tlx2
T cell leukemia homeobox 2
chr21_+_3960583 0.88 ENSDART00000149788
setx
senataxin
chr22_+_7462997 0.88 ENSDART00000106082
zgc:112368
zgc:112368
chr21_-_293146 0.85 ENSDART00000157781
plgrkt
plasminogen receptor, C-terminal lysine transmembrane protein
chr15_-_23645810 0.84 ENSDART00000168845
ckmb
creatine kinase, muscle b
chr19_-_30404096 0.84 ENSDART00000103475
agr2
anterior gradient 2
chr13_-_20540790 0.82 ENSDART00000131467
si:ch1073-126c3.2
si:ch1073-126c3.2
chr3_+_13624815 0.82 ENSDART00000161451
pglyrp6
peptidoglycan recognition protein 6
chr22_+_38194151 0.80 ENSDART00000121965
cp
ceruloplasmin
chr2_+_49864219 0.79 ENSDART00000187744
rpl37
ribosomal protein L37
chr23_+_25708787 0.78 ENSDART00000060059
rbms2b
RNA binding motif, single stranded interacting protein 2b
chr11_-_29650930 0.77 ENSDART00000166969
chd5
chromodomain helicase DNA binding protein 5
chr19_-_23871941 0.77 ENSDART00000134551
pimr92
Pim proto-oncogene, serine/threonine kinase, related 92
chr25_+_13791627 0.77 ENSDART00000159278
zgc:92873
zgc:92873
chr6_+_37894914 0.76 ENSDART00000148817
oca2
oculocutaneous albinism II
chr23_+_36083529 0.76 ENSDART00000053295
ENSDART00000130260
hoxc10a
homeobox C10a
chr6_+_25257728 0.75 ENSDART00000162581
kyat3
kynurenine aminotransferase 3
chr7_-_38658411 0.75 ENSDART00000109463
ENSDART00000017155
npsn
nephrosin
chr21_-_26071142 0.73 ENSDART00000004740
rab34b
RAB34, member RAS oncogene family b
chr4_+_11375894 0.72 ENSDART00000190471
ENSDART00000143963
pcloa
piccolo presynaptic cytomatrix protein a
chr22_+_7486867 0.72 ENSDART00000034586
CELA1 (1 of many)
zgc:112302
chr14_-_48260744 0.71 ENSDART00000183955
rxfp1
relaxin/insulin-like family peptide receptor 1
chr3_+_22442445 0.71 ENSDART00000190921
wnk4b
WNK lysine deficient protein kinase 4b
chr18_+_45504362 0.70 ENSDART00000140089
cngb1a
cyclic nucleotide gated channel beta 1a
chr7_+_25913225 0.70 ENSDART00000129924
hmgb3a
high mobility group box 3a
chr16_-_42013858 0.70 ENSDART00000045403
etv2
ets variant 2
chr7_-_25895189 0.68 ENSDART00000173599
ENSDART00000079235
ENSDART00000173786
ENSDART00000173602
ENSDART00000079245
ENSDART00000187568
ENSDART00000173505
cd99l2
CD99 molecule-like 2
chr17_-_43287290 0.68 ENSDART00000156885
EML5
si:dkey-1f12.3
chr19_-_30403922 0.67 ENSDART00000181841
agr2
anterior gradient 2
chr15_+_19544052 0.67 ENSDART00000062560
zgc:77784
zgc:77784
chr15_-_21877726 0.67 ENSDART00000127819
ENSDART00000145646
ENSDART00000100897
ENSDART00000144739
zgc:162608
zgc:162608
chr22_+_15624371 0.66 ENSDART00000124868
lpl
lipoprotein lipase
chr15_-_2657508 0.66 ENSDART00000102086
cldna
claudin a
chr5_-_38155005 0.66 ENSDART00000097770
gucy2d
guanylate cyclase 2D, retinal
chr17_-_6451801 0.66 ENSDART00000064700
fuca2
alpha-L-fucosidase 2
chr21_-_5879897 0.65 ENSDART00000184034
rpl35
ribosomal protein L35
chr11_+_40306579 0.64 ENSDART00000167504
si:dkey-207b20.2
si:dkey-207b20.2
chr8_+_45003659 0.63 ENSDART00000132663
si:ch211-163b2.4
si:ch211-163b2.4
chr10_+_36184751 0.63 ENSDART00000162639
or108-2
odorant receptor, family D, subfamily 108, member 2
chr20_+_10539293 0.63 ENSDART00000182265
serpina1l
serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1, like
chr11_+_705727 0.62 ENSDART00000165366
timp4.2
TIMP metallopeptidase inhibitor 4, tandem duplicate 2
chr1_-_44940830 0.62 ENSDART00000097500
ENSDART00000134464
ENSDART00000137216
tmem176
transmembrane protein 176
chr7_-_26087807 0.62 ENSDART00000052989
ache
acetylcholinesterase
chr8_+_12930216 0.62 ENSDART00000115405
KIF2A
zgc:103670
chr16_+_43347966 0.61 ENSDART00000171308
zmp:0000000930
zmp:0000000930
chr12_+_15622621 0.60 ENSDART00000079784
plcd3b
phospholipase C, delta 3b
chr14_-_31060082 0.60 ENSDART00000111601
ENSDART00000161113
mbnl3
muscleblind-like splicing regulator 3
chr2_-_55298075 0.60 ENSDART00000186404
ENSDART00000149062
rab8a
RAB8A, member RAS oncogene family
chr8_-_17926814 0.60 ENSDART00000147344
lhx8b
LIM homeobox 8b
chr22_+_7742211 0.59 ENSDART00000140896
CELA1 (1 of many)
zgc:92511
chr3_-_7170661 0.59 ENSDART00000190345
BX005085.4

chr11_+_25111846 0.59 ENSDART00000128705
ENSDART00000190058
ndrg3a
ndrg family member 3a
chr24_-_31846366 0.59 ENSDART00000155295
steap2
STEAP family member 2, metalloreductase
chr17_-_44584811 0.58 ENSDART00000165059
ENSDART00000165252
slc35f4
solute carrier family 35, member F4
chr3_-_32859335 0.57 ENSDART00000158916
si:dkey-16l2.20
si:dkey-16l2.20
chr19_+_10831362 0.57 ENSDART00000053325
tomm40l
translocase of outer mitochondrial membrane 40 homolog, like
chr11_-_26180714 0.57 ENSDART00000173597
kaznb
kazrin, periplakin interacting protein b
chr19_-_5103313 0.57 ENSDART00000037007
tpi1a
triosephosphate isomerase 1a
chr9_+_32930622 0.56 ENSDART00000100928
cnga4
cyclic nucleotide gated channel alpha 4
chr19_-_5103141 0.56 ENSDART00000150952
tpi1a
triosephosphate isomerase 1a
chr22_+_31821815 0.56 ENSDART00000159825
dock3
dedicator of cytokinesis 3
chr22_-_36876133 0.56 ENSDART00000147006
kng1
kininogen 1
chr11_+_40208239 0.56 ENSDART00000166171
si:ch211-193i15.1
si:ch211-193i15.1
chr7_+_22293894 0.56 ENSDART00000056790
tmem256
transmembrane protein 256
chr20_+_49119633 0.55 ENSDART00000151435
cd109
CD109 molecule
chr11_-_18604542 0.55 ENSDART00000171183
zmynd8
zinc finger, MYND-type containing 8
chr9_-_1970071 0.54 ENSDART00000080608
hoxd10a
homeobox D10a
chr22_-_17574511 0.54 ENSDART00000181496
pip5k1ca
phosphatidylinositol-4-phosphate 5-kinase, type I, gamma a
chr2_-_50198328 0.54 ENSDART00000074511
ENSDART00000137704
ahrrb
aryl-hydrocarbon receptor repressor b
chr13_+_42124566 0.54 ENSDART00000074707
cdc42ep3
CDC42 effector protein (Rho GTPase binding) 3
chr25_-_13842618 0.52 ENSDART00000160258
mapk8ip1a
mitogen-activated protein kinase 8 interacting protein 1a
chr2_-_58201173 0.52 ENSDART00000166282
pnp5b
purine nucleoside phosphorylase 5b
chr25_+_36316280 0.51 ENSDART00000152735
si:ch211-113a14.11
si:ch211-113a14.11
chr9_+_12934536 0.51 ENSDART00000134484
si:dkey-230p4.1
si:dkey-230p4.1
chr5_-_22027357 0.51 ENSDART00000023306
asb12a
ankyrin repeat and SOCS box-containing 12a
chr11_-_843811 0.51 ENSDART00000173331
atg7
ATG7 autophagy related 7 homolog (S. cerevisiae)
chr21_+_26071874 0.50 ENSDART00000003001
ENSDART00000146573
rpl23a
ribosomal protein L23a
chr5_-_63109232 0.50 ENSDART00000115128
usp2b
ubiquitin specific peptidase 2b
chr11_+_807153 0.50 ENSDART00000173289
vgll4b
vestigial-like family member 4b
chr19_-_23768865 0.49 ENSDART00000147081
pimr87
Pim proto-oncogene, serine/threonine kinase, related 87
chr15_+_23788154 0.49 ENSDART00000181482
ift20
intraflagellar transport 20 homolog (Chlamydomonas)
chr20_+_10545514 0.49 ENSDART00000153667
serpina1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr10_+_42374770 0.48 ENSDART00000020000
COX5B
zgc:86599
chr24_+_26432541 0.48 ENSDART00000105784
ENSDART00000122554
cldn11b
claudin 11b
chr5_+_38276582 0.48 ENSDART00000158532
gnb2
guanine nucleotide binding protein (G protein), beta polypeptide 2
chr6_-_8480815 0.47 ENSDART00000162300
rasal3
RAS protein activator like 3
chr2_-_11468654 0.46 ENSDART00000131229
slc44a5a
solute carrier family 44, member 5a
chr5_+_25072894 0.46 ENSDART00000012268
mrpl41
mitochondrial ribosomal protein L41
chr6_+_8176486 0.46 ENSDART00000193308
nfil3-5
nuclear factor, interleukin 3 regulated, member 5
chr22_+_7497319 0.45 ENSDART00000034564
CELA1 (1 of many)
zgc:92511
chr17_-_8862424 0.45 ENSDART00000064633
nkl.4
NK-lysin tandem duplicate 4
chr7_+_61480296 0.45 ENSDART00000083255
adam19a
ADAM metallopeptidase domain 19a
chr12_-_3940768 0.45 ENSDART00000134292
zgc:92040
zgc:92040
chr23_+_24604481 0.45 ENSDART00000146332
kansl2
KAT8 regulatory NSL complex subunit 2
chr20_-_9760424 0.44 ENSDART00000104936
si:dkey-63j12.4
si:dkey-63j12.4
chr7_-_28696556 0.44 ENSDART00000148822
adgrg1
adhesion G protein-coupled receptor G1
chr14_+_6159356 0.44 ENSDART00000157730
bscl2l
Bernardinelli-Seip congenital lipodystrophy 2, like
chr15_+_1004680 0.44 ENSDART00000157310
si:dkey-77f5.8
si:dkey-77f5.8
chr4_+_77021784 0.44 ENSDART00000135345
ENSDART00000133855
trpm2
transient receptor potential cation channel, subfamily M, member 2
chr10_+_466926 0.44 ENSDART00000145220
arvcfa
ARVCF, delta catenin family member a
chr14_-_40389699 0.43 ENSDART00000181581
ENSDART00000173398
pcdh19
protocadherin 19
chr22_-_26865361 0.43 ENSDART00000182504
hmox2a
heme oxygenase 2a
chr6_+_58832155 0.43 ENSDART00000144842
dctn2
dynactin 2 (p50)
chr23_-_1056808 0.43 ENSDART00000081961
zgc:113423
zgc:113423
chr6_-_1514767 0.42 ENSDART00000067586
chchd6b
coiled-coil-helix-coiled-coil-helix domain containing 6b
chr11_-_25213651 0.42 ENSDART00000097316
ENSDART00000152186
myh7ba
myosin, heavy chain 7B, cardiac muscle, beta a
chr9_-_23891102 0.42 ENSDART00000186799
asb18
ankyrin repeat and SOCS box containing 18

Network of associatons between targets according to the STRING database.

First level regulatory network of nr5a1a+nr5a2+nr5a5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:0032369 negative regulation of lipid transport(GO:0032369)
0.6 3.0 GO:0007060 male meiosis chromosome segregation(GO:0007060)
0.5 6.1 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.3 1.3 GO:0045988 regulation of twitch skeletal muscle contraction(GO:0014724) regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448) negative regulation of striated muscle contraction(GO:0045988) relaxation of skeletal muscle(GO:0090076)
0.3 1.1 GO:0046166 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.3 0.8 GO:0009595 detection of biotic stimulus(GO:0009595) detection of bacterium(GO:0016045) detection of other organism(GO:0098543) detection of external biotic stimulus(GO:0098581)
0.2 0.9 GO:0010755 regulation of plasminogen activation(GO:0010755)
0.2 0.6 GO:0035994 response to muscle stretch(GO:0035994)
0.2 1.2 GO:0048240 sperm capacitation(GO:0048240)
0.2 2.4 GO:0036158 outer dynein arm assembly(GO:0036158)
0.2 1.0 GO:0008584 male gonad development(GO:0008584)
0.2 1.0 GO:0097250 mitochondrial respiratory chain supercomplex assembly(GO:0097250)
0.2 1.9 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.2 1.5 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.2 0.6 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
0.1 0.6 GO:0015677 copper ion import(GO:0015677)
0.1 0.7 GO:0003096 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.1 0.7 GO:0010872 regulation of cholesterol esterification(GO:0010872) positive regulation of cholesterol esterification(GO:0010873)
0.1 0.9 GO:0003404 optic vesicle morphogenesis(GO:0003404)
0.1 0.9 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.1 0.5 GO:2000583 regulation of platelet-derived growth factor receptor signaling pathway(GO:0010640) platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790) regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583)
0.1 0.8 GO:0034389 lipid particle organization(GO:0034389)
0.1 1.4 GO:0030431 sleep(GO:0030431)
0.1 0.7 GO:0006004 fucose metabolic process(GO:0006004)
0.1 0.3 GO:1901295 negative regulation of striated muscle cell differentiation(GO:0051154) negative regulation of cardiac muscle tissue development(GO:0055026) cardiac muscle cell fate commitment(GO:0060923) canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:0061317) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901296) negative regulation of cardiocyte differentiation(GO:1905208) negative regulation of cardiac muscle cell differentiation(GO:2000726)
0.1 0.6 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.1 0.6 GO:0033986 response to methanol(GO:0033986) cellular response to methanol(GO:0071405)
0.1 0.4 GO:0014909 smooth muscle cell migration(GO:0014909)
0.1 2.1 GO:0001556 oocyte maturation(GO:0001556)
0.1 2.5 GO:0021884 forebrain neuron development(GO:0021884)
0.1 1.8 GO:0016584 nucleosome positioning(GO:0016584)
0.1 1.0 GO:0008090 retrograde axonal transport(GO:0008090)
0.1 2.3 GO:0006144 purine nucleobase metabolic process(GO:0006144)
0.1 0.7 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.1 0.4 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.1 0.3 GO:0042364 water-soluble vitamin biosynthetic process(GO:0042364) pyridoxal phosphate metabolic process(GO:0042822) pyridoxal phosphate biosynthetic process(GO:0042823)
0.1 0.5 GO:0071800 podosome assembly(GO:0071800)
0.1 0.8 GO:0042438 melanin biosynthetic process(GO:0042438)
0.1 0.3 GO:0090069 regulation of ribosome biogenesis(GO:0090069)
0.1 1.2 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.1 0.3 GO:1901492 positive regulation of lymphangiogenesis(GO:1901492)
0.1 0.6 GO:0030195 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.1 0.2 GO:0015824 proline transport(GO:0015824)
0.1 5.3 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.1 0.4 GO:0071480 response to gamma radiation(GO:0010332) cellular response to gamma radiation(GO:0071480)
0.1 0.2 GO:0033212 iron assimilation(GO:0033212)
0.1 0.4 GO:0070445 regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.1 0.5 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.1 0.7 GO:1904071 presynaptic active zone assembly(GO:1904071)
0.1 0.4 GO:0006788 heme oxidation(GO:0006788)
0.1 1.3 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 0.8 GO:0006603 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.1 0.7 GO:0045762 activation of adenylate cyclase activity(GO:0007190) positive regulation of cAMP metabolic process(GO:0030816) positive regulation of cAMP biosynthetic process(GO:0030819) positive regulation of adenylate cyclase activity(GO:0045762)
0.1 0.2 GO:0070126 mitochondrial translational termination(GO:0070126)
0.1 0.2 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.1 2.8 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.1 0.8 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.1 0.8 GO:0006825 copper ion transport(GO:0006825)
0.1 0.5 GO:0031272 pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.1 0.9 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.1 0.3 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.1 0.2 GO:0015860 intracellular nucleoside transport(GO:0015859) purine nucleoside transmembrane transport(GO:0015860) purine nucleotide transport(GO:0015865) ATP transport(GO:0015867) purine ribonucleotide transport(GO:0015868) adenine nucleotide transport(GO:0051503) mitochondrial ATP transmembrane transport(GO:1990544)
0.1 1.2 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.1 GO:0006097 glyoxylate cycle(GO:0006097)
0.0 1.2 GO:0010508 positive regulation of autophagy(GO:0010508)
0.0 1.4 GO:0097194 execution phase of apoptosis(GO:0097194)
0.0 1.6 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.2 GO:0006843 mitochondrial citrate transport(GO:0006843)
0.0 0.2 GO:0048795 swim bladder morphogenesis(GO:0048795)
0.0 1.0 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.4 GO:0034381 plasma lipoprotein particle clearance(GO:0034381) long-chain fatty acid import(GO:0044539)
0.0 2.0 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 0.2 GO:0060832 oocyte animal/vegetal axis specification(GO:0060832)
0.0 0.4 GO:0060004 reflex(GO:0060004) vestibular reflex(GO:0060005) vestibular receptor cell differentiation(GO:0060114) vestibular receptor cell development(GO:0060118)
0.0 0.7 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.4 GO:0030719 P granule organization(GO:0030719)
0.0 1.1 GO:0070831 basement membrane assembly(GO:0070831)
0.0 0.4 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.1 GO:0009957 epidermal cell fate specification(GO:0009957)
0.0 1.0 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.0 12.8 GO:0046777 protein autophosphorylation(GO:0046777)
0.0 0.3 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0 0.2 GO:0003151 outflow tract morphogenesis(GO:0003151)
0.0 1.3 GO:0070830 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.0 0.3 GO:0036368 cone photoresponse recovery(GO:0036368)
0.0 0.3 GO:0060612 adipose tissue development(GO:0060612)
0.0 0.7 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 1.6 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 0.6 GO:0051289 protein homotetramerization(GO:0051289)
0.0 0.2 GO:0019430 response to superoxide(GO:0000303) response to oxygen radical(GO:0000305) removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.0 0.4 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.1 GO:0051661 Golgi localization(GO:0051645) maintenance of centrosome location(GO:0051661)
0.0 0.1 GO:0035889 otolith tethering(GO:0035889)
0.0 1.3 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 0.5 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.3 GO:0010765 positive regulation of sodium ion transport(GO:0010765) positive regulation of sodium ion transmembrane transport(GO:1902307) regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288) positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.0 0.4 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.0 1.5 GO:0006694 steroid biosynthetic process(GO:0006694)
0.0 1.0 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 0.6 GO:0015012 heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.0 0.2 GO:0035094 response to nicotine(GO:0035094)
0.0 0.5 GO:0035329 hippo signaling(GO:0035329)
0.0 1.0 GO:0031017 exocrine pancreas development(GO:0031017) exocrine system development(GO:0035272)
0.0 0.3 GO:0007257 activation of JUN kinase activity(GO:0007257) positive regulation of JUN kinase activity(GO:0043507)
0.0 0.2 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.4 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.5 GO:0046328 regulation of JNK cascade(GO:0046328)
0.0 0.1 GO:0001840 neural plate development(GO:0001840)
0.0 1.7 GO:0001503 ossification(GO:0001503)
0.0 0.1 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 0.4 GO:0072015 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.0 0.3 GO:0033555 multicellular organismal response to stress(GO:0033555)
0.0 0.1 GO:0039023 pronephric duct morphogenesis(GO:0039023)
0.0 0.5 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.0 0.7 GO:0006805 xenobiotic metabolic process(GO:0006805)
0.0 0.4 GO:0048854 brain morphogenesis(GO:0048854)
0.0 0.0 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.5 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 1.0 GO:0051260 protein homooligomerization(GO:0051260)
0.0 0.9 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.2 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.2 GO:0046838 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855) inositol phosphate catabolic process(GO:0071545)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:1902560 GMP reductase complex(GO:1902560)
0.3 1.3 GO:0031673 H zone(GO:0031673)
0.2 2.4 GO:0036157 outer dynein arm(GO:0036157)
0.2 1.2 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.1 1.6 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.1 1.3 GO:0042627 chylomicron(GO:0042627)
0.1 1.6 GO:0045277 respiratory chain complex IV(GO:0045277)
0.1 0.3 GO:0008247 1-alkyl-2-acetylglycerophosphocholine esterase complex(GO:0008247)
0.1 0.5 GO:0001891 phagocytic cup(GO:0001891)
0.1 0.7 GO:0098982 GABA-ergic synapse(GO:0098982)
0.1 2.8 GO:0016605 PML body(GO:0016605)
0.1 2.9 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 0.4 GO:0035253 ciliary rootlet(GO:0035253)
0.1 0.6 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 1.1 GO:0005605 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.0 0.3 GO:0071986 Ragulator complex(GO:0071986)
0.0 3.0 GO:0005930 axoneme(GO:0005930)
0.0 0.4 GO:0061617 MICOS complex(GO:0061617)
0.0 0.5 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 1.6 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.4 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.2 GO:0032019 mitochondrial cloud(GO:0032019)
0.0 0.4 GO:0005869 dynactin complex(GO:0005869)
0.0 1.9 GO:0005814 centriole(GO:0005814)
0.0 0.3 GO:0045095 keratin filament(GO:0045095)
0.0 1.3 GO:0031514 motile cilium(GO:0031514)
0.0 0.6 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.3 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 2.1 GO:0000786 nucleosome(GO:0000786)
0.0 0.8 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 2.2 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 1.2 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 1.0 GO:0042641 actomyosin(GO:0042641)
0.0 0.4 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.3 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.2 GO:0005746 mitochondrial respiratory chain(GO:0005746)
0.0 0.2 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.1 GO:0031616 spindle pole centrosome(GO:0031616)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:0003920 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.5 3.0 GO:0032052 bile acid binding(GO:0032052)
0.3 1.4 GO:0015355 secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.3 2.3 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.3 1.3 GO:0005521 lamin binding(GO:0005521)
0.3 0.9 GO:0001160 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.3 2.6 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.3 1.1 GO:0004807 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
0.3 0.8 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.3 7.0 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.2 0.7 GO:0034185 apolipoprotein binding(GO:0034185)
0.2 0.7 GO:0015928 alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928)
0.2 2.4 GO:0045503 dynein light chain binding(GO:0045503)
0.1 1.2 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 0.6 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.1 0.7 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.1 0.6 GO:0008432 JUN kinase binding(GO:0008432)
0.1 0.4 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.1 0.4 GO:0072571 ADP-D-ribose binding(GO:0072570) mono-ADP-D-ribose binding(GO:0072571)
0.1 0.6 GO:0004104 cholinesterase activity(GO:0004104)
0.1 0.5 GO:0001223 transcription coactivator binding(GO:0001223)
0.1 0.5 GO:0019779 Atg12 activating enzyme activity(GO:0019778) Atg8 activating enzyme activity(GO:0019779)
0.1 0.4 GO:0048407 platelet-derived growth factor-activated receptor activity(GO:0005017) platelet-derived growth factor binding(GO:0048407)
0.1 1.3 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.1 0.4 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.1 0.4 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
0.1 1.4 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1 0.2 GO:0000996 core DNA-dependent RNA polymerase binding promoter specificity activity(GO:0000996) mitochondrial RNA polymerase binding promoter specificity activity(GO:0034246)
0.1 1.8 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 1.1 GO:0008266 poly(U) RNA binding(GO:0008266)
0.1 0.3 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.1 0.2 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086)
0.1 0.4 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.1 1.0 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 0.8 GO:0016775 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.1 0.2 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 1.0 GO:0019869 chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.1 0.3 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.1 0.7 GO:0042285 xylosyltransferase activity(GO:0042285)
0.1 0.5 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.1 0.2 GO:2001070 starch binding(GO:2001070)
0.1 0.8 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 7.7 GO:0005179 hormone activity(GO:0005179)
0.1 0.2 GO:0005471 ATP:ADP antiporter activity(GO:0005471)
0.1 0.3 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.0 0.1 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.0 0.6 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.6 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 1.9 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.3 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.9 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 2.0 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.7 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.0 0.6 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.0 0.7 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.7 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 5.9 GO:0008083 growth factor activity(GO:0008083)
0.0 0.2 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.0 1.6 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.3 GO:0043515 kinetochore binding(GO:0043515)
0.0 1.0 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.5 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.0 0.3 GO:0004145 diamine N-acetyltransferase activity(GO:0004145)
0.0 0.2 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.3 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.0 1.2 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.5 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 1.3 GO:0019843 rRNA binding(GO:0019843)
0.0 0.4 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828)
0.0 0.2 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.6 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 1.2 GO:0071949 FAD binding(GO:0071949)
0.0 5.1 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.9 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.2 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.2 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.1 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0 0.2 GO:0004096 catalase activity(GO:0004096)
0.0 0.6 GO:0004629 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 0.3 GO:0031726 CCR1 chemokine receptor binding(GO:0031726) CCR4 chemokine receptor binding(GO:0031729)
0.0 0.6 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.5 GO:0016307 phosphatidylinositol phosphate kinase activity(GO:0016307)
0.0 0.6 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.9 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.0 0.3 GO:0016641 FMN binding(GO:0010181) oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0 1.7 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 1.8 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.3 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.5 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.8 PID ALK2 PATHWAY ALK2 signaling events
0.1 1.4 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 0.2 PID FOXO PATHWAY FoxO family signaling
0.1 0.6 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 1.7 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 1.3 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.5 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 0.7 PID CONE PATHWAY Visual signal transduction: Cones
0.0 7.3 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.9 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.7 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 3.3 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.2 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.4 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.2 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.3 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.9 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.3 2.3 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.3 2.6 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.3 1.0 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.2 2.3 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.2 1.4 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 1.6 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.1 6.5 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.1 0.7 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 1.0 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.8 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.0 0.6 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.3 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.6 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 1.2 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.0 0.6 REACTOME KINESINS Genes involved in Kinesins
0.0 0.5 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.4 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 1.3 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.2 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 1.9 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.3 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 0.2 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.8 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.1 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors