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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for nrf1

Z-value: 1.88

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Transcription factors associated with nrf1

Gene Symbol Gene ID Gene Info
nrf1
ENSDARG00000000018 nuclear respiratory factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nrf1dr11_v1_chr4_-_15103646_151036960.982.4e-13Click!

Activity profile of nrf1 motif

Sorted Z-values of nrf1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr15_-_45538773 5.75 ENSDART00000113494
MB21D2
Mab-21 domain containing 2
chr15_-_28587147 5.14 ENSDART00000156049
ssh2a
slingshot protein phosphatase 2a
chr25_+_22320738 4.30 ENSDART00000073566
cyp11a1
cytochrome P450, family 11, subfamily A, polypeptide 1
chr25_+_22319940 4.16 ENSDART00000154065
ENSDART00000153492
ENSDART00000024866
ENSDART00000154376
cyp11a1
cytochrome P450, family 11, subfamily A, polypeptide 1
chr3_+_48473346 3.95 ENSDART00000166294
metrnl
meteorin, glial cell differentiation regulator-like
chr20_-_182841 3.94 ENSDART00000064546
si:ch211-241j12.3
si:ch211-241j12.3
chr1_+_51615672 3.92 ENSDART00000165117
zgc:165656
zgc:165656
chr17_+_33415319 3.71 ENSDART00000140805
ENSDART00000025501
ENSDART00000146447
snap23.1
synaptosomal-associated protein 23.1
chr8_+_7875110 3.63 ENSDART00000167423
ENSDART00000160267
ENSDART00000180490
mbd1a
methyl-CpG binding domain protein 1a
chr24_-_42072886 3.58 ENSDART00000171389
CABZ01095370.1

chr3_+_51563695 3.55 ENSDART00000008607
ttyh2l
tweety homolog 2, like
chr12_+_47081783 3.54 ENSDART00000158568
mtr
5-methyltetrahydrofolate-homocysteine methyltransferase
chr15_+_44201056 3.47 ENSDART00000162433
ENSDART00000148336
CU655961.4

chr17_+_33415542 3.42 ENSDART00000183169
snap23.1
synaptosomal-associated protein 23.1
chr7_-_41881177 3.39 ENSDART00000174258
ENSDART00000018972
zgc:92818
zgc:92818
chr19_-_18127808 3.39 ENSDART00000108627
snx10a
sorting nexin 10a
chr23_-_31810222 3.27 ENSDART00000134319
ENSDART00000139076
hbs1l
HBS1-like translational GTPase
chr6_-_9676108 3.12 ENSDART00000169915
nop58
NOP58 ribonucleoprotein homolog (yeast)
chr25_+_8921425 3.08 ENSDART00000128591
accs
1-aminocyclopropane-1-carboxylate synthase homolog (Arabidopsis)(non-functional)
chr11_-_6452444 3.05 ENSDART00000137879
ENSDART00000134957
ENSDART00000004483
larp6b
La ribonucleoprotein domain family, member 6b
chr19_-_18127629 3.05 ENSDART00000187722
snx10a
sorting nexin 10a
chr2_-_47620806 3.00 ENSDART00000038228
ap1s3b
adaptor-related protein complex 1, sigma 3 subunit, b
chr15_-_30984557 2.99 ENSDART00000080328
nf1a
neurofibromin 1a
chr15_-_4415917 2.96 ENSDART00000062874
atp1b3b
ATPase Na+/K+ transporting subunit beta 3b
chr7_+_57088920 2.94 ENSDART00000024076
scamp2l
secretory carrier membrane protein 2, like
chr19_-_47832853 2.89 ENSDART00000170988
ago4
argonaute RISC catalytic component 4
chr17_-_20167206 2.88 ENSDART00000104874
ENSDART00000191995
p4ha1b
prolyl 4-hydroxylase, alpha polypeptide I b
chr11_-_30508843 2.88 ENSDART00000101667
ENSDART00000179930
map4k3a
mitogen-activated protein kinase kinase kinase kinase 3a
chr19_+_28291062 2.87 ENSDART00000163382
lpcat1
lysophosphatidylcholine acyltransferase 1
chr19_-_30800004 2.86 ENSDART00000128560
ENSDART00000045504
ENSDART00000125893
trit1
tRNA isopentenyltransferase 1
chr19_+_28291376 2.79 ENSDART00000139433
ENSDART00000103855
lpcat1
lysophosphatidylcholine acyltransferase 1
chr25_+_7532627 2.79 ENSDART00000187660
ptdss2
phosphatidylserine synthase 2
chr22_-_15704704 2.79 ENSDART00000017838
ENSDART00000130238
safb
scaffold attachment factor B
chr2_-_58075414 2.78 ENSDART00000161920
nectin4
nectin cell adhesion molecule 4
chr7_+_57089354 2.75 ENSDART00000140702
scamp2l
secretory carrier membrane protein 2, like
chr21_-_34032650 2.75 ENSDART00000138575
ENSDART00000047515
rnf145b
ring finger protein 145b
chr15_-_30984804 2.72 ENSDART00000157005
nf1a
neurofibromin 1a
chr25_-_37121335 2.71 ENSDART00000017805
nfat5a
nuclear factor of activated T cells 5a
chr24_+_35911020 2.69 ENSDART00000088480
abcd4
ATP-binding cassette, sub-family D (ALD), member 4
chr4_-_10835620 2.68 ENSDART00000150739
ppfibp1a
PTPRF interacting protein, binding protein 1a (liprin beta 1)
chr7_+_46020508 2.67 ENSDART00000170294
ccne1
cyclin E1
chr13_-_24826607 2.64 ENSDART00000087786
ENSDART00000186951
slka
STE20-like kinase a
chr24_+_35911300 2.62 ENSDART00000129679
abcd4
ATP-binding cassette, sub-family D (ALD), member 4
chr6_-_19341184 2.58 ENSDART00000168236
ENSDART00000167674
mif4gda
MIF4G domain containing a
chr22_+_21549419 2.57 ENSDART00000139411
plpp2b
phospholipid phosphatase 2b
chr5_-_24882357 2.57 ENSDART00000127773
ENSDART00000003998
ENSDART00000143851
ewsr1b
EWS RNA-binding protein 1b
chr15_-_28587490 2.55 ENSDART00000186196
ssh2a
slingshot protein phosphatase 2a
chr6_-_7776612 2.53 ENSDART00000190269
myh9a
myosin, heavy chain 9a, non-muscle
chr25_+_7532811 2.52 ENSDART00000161593
ptdss2
phosphatidylserine synthase 2
chr8_+_144154 2.50 ENSDART00000164099
snx2
sorting nexin 2
chr17_-_33415740 2.50 ENSDART00000135218
ccdc28a
coiled-coil domain containing 28A
chr5_-_69716501 2.50 ENSDART00000158956
mob1a
MOB kinase activator 1A
chr23_-_26227805 2.48 ENSDART00000158082
BX927204.1

chr10_+_3145707 2.47 ENSDART00000160046
hic2
hypermethylated in cancer 2
chr8_-_34427364 2.47 ENSDART00000112854
ENSDART00000161282
ENSDART00000113230
gapvd1
GTPase activating protein and VPS9 domains 1
chr22_+_14117078 2.43 ENSDART00000013575
bzw1a
basic leucine zipper and W2 domains 1a
chr5_-_56964547 2.43 ENSDART00000074400
tia1
TIA1 cytotoxic granule-associated RNA binding protein
chr6_-_37744430 2.40 ENSDART00000150177
ENSDART00000149722
nipa2
non imprinted in Prader-Willi/Angelman syndrome 2 (human)
chr5_-_19932621 2.40 ENSDART00000088881
git2a
G protein-coupled receptor kinase interacting ArfGAP 2a
chr21_-_4849029 2.38 ENSDART00000168930
ENSDART00000151019
notch1a
notch 1a
chr13_+_39277178 2.38 ENSDART00000113259
si:dkey-85a20.4
si:dkey-85a20.4
chr4_+_2482046 2.38 ENSDART00000103371
zdhhc17
zinc finger, DHHC-type containing 17
chr23_+_10805188 2.37 ENSDART00000035693
ppp4r2a
protein phosphatase 4, regulatory subunit 2a
chr11_+_5565082 2.36 ENSDART00000112590
ENSDART00000183207
si:ch73-40i7.5
si:ch73-40i7.5
chr23_-_26228077 2.36 ENSDART00000162423
BX927204.1

chr20_+_38543542 2.35 ENSDART00000145254
gtf3c2
general transcription factor IIIC, polypeptide 2, beta
chr5_-_6745442 2.35 ENSDART00000157402
ENSDART00000128684
ENSDART00000168698
ostf1
osteoclast stimulating factor 1
chr25_+_753364 2.35 ENSDART00000183804
TWF1 (1 of many)
twinfilin actin binding protein 1
chr5_-_24008997 2.34 ENSDART00000066645
eif1axa
eukaryotic translation initiation factor 1A, X-linked, a
chr21_-_14878220 2.34 ENSDART00000131237
ulk1b
unc-51 like autophagy activating kinase 1
chr13_-_48161568 2.30 ENSDART00000109469
ENSDART00000188052
ENSDART00000193446
ENSDART00000189509
ENSDART00000184810
golga4
golgin A4
chr15_+_44184367 2.29 ENSDART00000162918
ENSDART00000110060
zgc:165514
zgc:165514
chr1_-_53407448 2.26 ENSDART00000160033
ENSDART00000172322
elmod2
ELMO/CED-12 domain containing 2
chr6_-_19340889 2.26 ENSDART00000181407
mif4gda
MIF4G domain containing a
chr5_+_47862636 2.22 ENSDART00000139824
rasa1a
RAS p21 protein activator (GTPase activating protein) 1a
chr2_-_7131657 2.21 ENSDART00000175565
ENSDART00000092116
extl2
exostosin-like glycosyltransferase 2
chr21_-_11367271 2.20 ENSDART00000151000
ENSDART00000151465
zgc:162472
zgc:162472
chr21_-_18275226 2.19 ENSDART00000126672
ENSDART00000135239
brd3a
bromodomain containing 3a
chr2_-_57076687 2.17 ENSDART00000161523
slc25a42
solute carrier family 25, member 42
chr14_-_763744 2.13 ENSDART00000165856
trim35-27
tripartite motif containing 35-27
chr14_+_46118834 2.13 ENSDART00000124417
ENSDART00000017785
naa15a
N(alpha)-acetyltransferase 15, NatA auxiliary subunit a
chr12_+_36428052 2.12 ENSDART00000131300
unk
unkempt family zinc finger
chr6_-_9695294 2.11 ENSDART00000162728
nop58
NOP58 ribonucleoprotein homolog (yeast)
chr9_-_32177117 2.09 ENSDART00000078568
sf3b1
splicing factor 3b, subunit 1
chr14_-_24277805 2.07 ENSDART00000054243
dpf2l
D4, zinc and double PHD fingers family 2, like
chr8_+_23861461 2.07 ENSDART00000037109
srpk1a
SRSF protein kinase 1a
chr9_+_25096500 2.06 ENSDART00000135074
ENSDART00000180436
ENSDART00000108629
lrch1
leucine-rich repeats and calponin homology (CH) domain containing 1
chr17_-_868004 2.04 ENSDART00000112803
wdr20a
WD repeat domain 20a
chr2_-_17492486 2.04 ENSDART00000189464
kdm4ab
lysine (K)-specific demethylase 4A, genome duplicate b
chr11_+_5468629 2.04 ENSDART00000013203
cse1l
CSE1 chromosome segregation 1-like (yeast)
chr8_+_13064750 2.03 ENSDART00000039878
sap30bp
SAP30 binding protein
chr18_+_3579829 2.02 ENSDART00000158763
ENSDART00000182850
ENSDART00000162754
ENSDART00000178789
ENSDART00000172656
lrch3
leucine-rich repeats and calponin homology (CH) domain containing 3
chr11_+_2649664 2.01 ENSDART00000166357
si:ch211-160o17.4
si:ch211-160o17.4
chr7_-_32629458 2.00 ENSDART00000001376
arl14ep
ADP-ribosylation factor-like 14 effector protein
chr6_-_7686594 1.99 ENSDART00000091836
ENSDART00000151697
ubn2a
ubinuclein 2a
chr22_+_336256 1.99 ENSDART00000019155
btg2
B-cell translocation gene 2
chr12_-_9468618 1.98 ENSDART00000152737
ENSDART00000091519
pgap3
post-GPI attachment to proteins 3
chr1_+_45925365 1.97 ENSDART00000144245
eif5b
eukaryotic translation initiation factor 5B
chr6_-_12900154 1.97 ENSDART00000080408
ENSDART00000150887
ical1
islet cell autoantigen 1-like
chr19_+_366034 1.95 ENSDART00000093383
vps72
vacuolar protein sorting 72 homolog (S. cerevisiae)
chr4_+_25181572 1.94 ENSDART00000078529
ENSDART00000136643
kin
Kin17 DNA and RNA binding protein
chr5_+_62319217 1.93 ENSDART00000050879
pho
phoenix
chr13_-_33246154 1.93 ENSDART00000130127
rtf1
RTF1 homolog, Paf1/RNA polymerase II complex component
chr3_+_43086548 1.93 ENSDART00000163579
si:dkey-43p13.5
si:dkey-43p13.5
chr1_+_45925150 1.92 ENSDART00000074689
eif5b
eukaryotic translation initiation factor 5B
chr15_+_44250335 1.90 ENSDART00000186162
ENSDART00000193503
ENSDART00000180275
zgc:162962
zgc:162962
chr9_+_37366973 1.90 ENSDART00000016370
dirc2
disrupted in renal carcinoma 2
chr2_+_21356242 1.89 ENSDART00000145670
ENSDART00000146600
ctdsplb
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like b
chr14_-_46198373 1.89 ENSDART00000031640
ENSDART00000132966
zgc:113425
zgc:113425
chr24_+_39129316 1.89 ENSDART00000155346
tbc1d24
TBC1 domain family, member 24
chr11_+_2649891 1.88 ENSDART00000093052
si:ch211-160o17.4
si:ch211-160o17.4
chr21_+_43702016 1.86 ENSDART00000017176
dkc1
dyskeratosis congenita 1, dyskerin
chr15_+_38221038 1.85 ENSDART00000188149
stim1a
stromal interaction molecule 1a
chr5_+_36666715 1.84 ENSDART00000097686
zgc:153990
zgc:153990
chr8_-_45939691 1.83 ENSDART00000040066
ENSDART00000132297
adam9
ADAM metallopeptidase domain 9
chr13_+_9368621 1.83 ENSDART00000109126
alms1
Alstrom syndrome protein 1
chr14_-_26411918 1.83 ENSDART00000020582
tmed9
transmembrane p24 trafficking protein 9
chr18_-_40913294 1.83 ENSDART00000059196
ENSDART00000098878
polr2i
polymerase (RNA) II (DNA directed) polypeptide I
chr6_-_29086473 1.82 ENSDART00000124947
evi5b
ecotropic viral integration site 5b
chr9_+_38588081 1.81 ENSDART00000031127
ENSDART00000131784
snx4
sorting nexin 4
chr1_+_47165842 1.80 ENSDART00000053152
ENSDART00000167051
cbr1
carbonyl reductase 1
chr13_+_49727333 1.80 ENSDART00000168799
ENSDART00000037559
ggps1
geranylgeranyl diphosphate synthase 1
chr13_-_35844961 1.80 ENSDART00000171371
map3k4
mitogen-activated protein kinase kinase kinase 4
chr9_-_34945566 1.79 ENSDART00000131908
ENSDART00000059861
dcun1d2a
DCN1, defective in cullin neddylation 1, domain containing 2a
chr12_-_2800809 1.79 ENSDART00000152682
ENSDART00000083784
ubtd1b
ubiquitin domain containing 1b
chr23_+_12160900 1.78 ENSDART00000136046
ppp1r3da
protein phosphatase 1, regulatory subunit 3Da
chr23_-_29569827 1.77 ENSDART00000078300
ENSDART00000133576
ENSDART00000158349
nmnat1-rbp7a
nmnat1
nmnat1-rbp7a readthrough
nicotinamide nucleotide adenylyltransferase 1
chr7_+_29044888 1.76 ENSDART00000086871
gfod2
glucose-fructose oxidoreductase domain containing 2
chr6_+_149405 1.75 ENSDART00000161154
fdx1l
ferredoxin 1-like
chr6_+_27667359 1.75 ENSDART00000159624
ENSDART00000049177
rab6ba
RAB6B, member RAS oncogene family a
chr8_+_21225064 1.74 ENSDART00000129210
cry1ba
cryptochrome circadian clock 1ba
chr1_+_57347888 1.74 ENSDART00000104222
b3gntl1
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1
chr21_-_3613702 1.72 ENSDART00000139194
dym
dymeclin
chr24_-_25166720 1.72 ENSDART00000141601
phldb2b
pleckstrin homology-like domain, family B, member 2b
chr17_+_28706946 1.70 ENSDART00000126967
strn3
striatin, calmodulin binding protein 3
chr25_-_35296165 1.69 ENSDART00000018107
fancf
Fanconi anemia, complementation group F
chr1_-_50247 1.69 ENSDART00000168428
ildr1a
immunoglobulin-like domain containing receptor 1a
chr1_+_260039 1.68 ENSDART00000092584
ENSDART00000111806
cenpe
centromere protein E
chr3_+_15736811 1.68 ENSDART00000080075
phb
prohibitin
chr3_+_18579806 1.67 ENSDART00000180967
ENSDART00000089765
arhgap17b
Rho GTPase activating protein 17b
chr9_-_25328527 1.67 ENSDART00000060840
med4
mediator complex subunit 4
chr2_+_22363824 1.67 ENSDART00000163172
hs2st1a
heparan sulfate 2-O-sulfotransferase 1a
chr2_+_21356500 1.66 ENSDART00000171397
ctdsplb
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like b
chr14_-_9085349 1.65 ENSDART00000054710
polr1d
polymerase (RNA) I polypeptide D
chr24_-_25166416 1.65 ENSDART00000111552
ENSDART00000169495
phldb2b
pleckstrin homology-like domain, family B, member 2b
chr7_+_56703254 1.65 ENSDART00000184547
ENSDART00000004964
ENSDART00000147259
ENSDART00000134173
nqo1
NAD(P)H dehydrogenase, quinone 1
chr7_+_17096281 1.64 ENSDART00000035558
htatip2
HIV-1 Tat interactive protein 2
chr11_+_45110865 1.64 ENSDART00000158188
mgea5l
meningioma expressed antigen 5 (hyaluronidase) like
chr7_+_66884291 1.62 ENSDART00000187499
sbf2
SET binding factor 2
chr8_-_25034411 1.60 ENSDART00000135973
nfyal
nuclear transcription factor Y, alpha, like
chr11_+_26375979 1.60 ENSDART00000087652
ENSDART00000171748
ENSDART00000103513
ENSDART00000165931
ENSDART00000170043
cpne1
rbm12
copine I
RNA binding motif protein 12
chr21_-_30160411 1.58 ENSDART00000126621
pfdn1
prefoldin subunit 1
chr19_-_432083 1.58 ENSDART00000165371
dus3l
dihydrouridine synthase 3-like (S. cerevisiae)
chr5_+_51226846 1.58 ENSDART00000138210
ubac1
UBA domain containing 1
chr13_+_25364753 1.57 ENSDART00000027428
chuk
conserved helix-loop-helix ubiquitous kinase
chr23_+_45845159 1.57 ENSDART00000023944
lmnl3
lamin L3
chr14_+_21699129 1.57 ENSDART00000073707
stx3a
syntaxin 3A
chr8_-_49935358 1.57 ENSDART00000159782
ENSDART00000156841
agtpbp1
CU694202.1
ATP/GTP binding protein 1

chr16_-_52540056 1.56 ENSDART00000188304
CR293507.1

chr6_-_18228358 1.56 ENSDART00000167937
p4hb
prolyl 4-hydroxylase, beta polypeptide
chr5_+_51227147 1.56 ENSDART00000083340
ubac1
UBA domain containing 1
chr10_+_26990095 1.56 ENSDART00000064111
faub
Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed b
chr13_+_25364324 1.55 ENSDART00000187471
chuk
conserved helix-loop-helix ubiquitous kinase
chr4_-_11024767 1.55 ENSDART00000067261
ENSDART00000167631
tmtc2a
transmembrane and tetratricopeptide repeat containing 2a
chr2_+_25839650 1.55 ENSDART00000134077
ENSDART00000140804
eif5a2
eukaryotic translation initiation factor 5A2
chr3_-_26341959 1.55 ENSDART00000169344
ENSDART00000142878
ENSDART00000087196
zgc:153240
zgc:153240
chr22_-_17677947 1.54 ENSDART00000139911
tjp3
tight junction protein 3
chr11_+_31236001 1.52 ENSDART00000129393
trmt1
tRNA methyltransferase 1
chr5_+_59030096 1.52 ENSDART00000179814
ENSDART00000110182
rabep1
rabaptin, RAB GTPase binding effector protein 1
chr2_-_17492080 1.52 ENSDART00000024302
kdm4ab
lysine (K)-specific demethylase 4A, genome duplicate b
chr21_-_11327830 1.51 ENSDART00000122331
rtkn2b
rhotekin 2b
chr13_-_9367647 1.51 ENSDART00000083362
ENSDART00000144146
si:dkey-33c12.4
si:dkey-33c12.4
chr4_-_5018705 1.51 ENSDART00000154025
strip2
striatin interacting protein 2
chr23_-_27442544 1.51 ENSDART00000019521
dip2ba
disco-interacting protein 2 homolog Ba
chr2_+_30182431 1.50 ENSDART00000004903
rdh10b
retinol dehydrogenase 10b
chr16_-_7793457 1.50 ENSDART00000113483
trim71
tripartite motif containing 71, E3 ubiquitin protein ligase
chr15_+_38221196 1.49 ENSDART00000122134
ENSDART00000190099
stim1a
stromal interaction molecule 1a
chr5_+_30986512 1.48 ENSDART00000005893
ube2g1a
ubiquitin-conjugating enzyme E2G 1a (UBC7 homolog, yeast)
chr12_-_13966184 1.48 ENSDART00000066368
klhl11
kelch-like family member 11
chr20_-_25445237 1.48 ENSDART00000145034
ENSDART00000018049
mrpl19
mitochondrial ribosomal protein L19
chr10_-_3394256 1.47 ENSDART00000158315
ENSDART00000111241
naa25
N(alpha)-acetyltransferase 25, NatB auxiliary subunit
chr23_-_31810391 1.46 ENSDART00000189749
ENSDART00000180850
hbs1l
HBS1-like translational GTPase
chr9_+_711822 1.45 ENSDART00000136627
ybey
ybeY metallopeptidase
chr15_+_24549054 1.44 ENSDART00000155900
phf12b
PHD finger protein 12b
chr4_+_9911043 1.44 ENSDART00000159762
ENSDART00000091599
sbf1
SET binding factor 1
chr17_-_33414781 1.44 ENSDART00000142203
ENSDART00000034638
ccdc28a
coiled-coil domain containing 28A
chr1_+_15258641 1.43 ENSDART00000033018
pi4k2b
phosphatidylinositol 4-kinase type 2 beta
chr25_+_2776865 1.43 ENSDART00000156567
neo1b
neogenin 1b
chr24_-_7957581 1.42 ENSDART00000145815
txndc5
thioredoxin domain containing 5
chr24_+_42004640 1.42 ENSDART00000171380
top1mt
DNA topoisomerase I mitochondrial
chr16_+_54303491 1.41 ENSDART00000043403
ethe1
ethylmalonic encephalopathy 1
chr9_+_34380299 1.40 ENSDART00000131705
lamp1
lysosomal-associated membrane protein 1
chr13_+_6189203 1.40 ENSDART00000109665
ppm1g
protein phosphatase, Mg2+/Mn2+ dependent, 1G
chr9_+_711638 1.39 ENSDART00000191964
ybey
ybeY metallopeptidase
chr13_+_159504 1.38 ENSDART00000057248
ewsr1b
EWS RNA-binding protein 1b
chr1_-_59243542 1.37 ENSDART00000163021
mvb12a
multivesicular body subunit 12A
chr24_-_42090635 1.36 ENSDART00000166413
ssr1
signal sequence receptor, alpha
chr21_+_18405585 1.36 ENSDART00000139318
si:dkey-1d7.3
si:dkey-1d7.3
chr10_+_7703251 1.36 ENSDART00000165134
ggcx
gamma-glutamyl carboxylase
chr7_+_66884570 1.35 ENSDART00000082664
sbf2
SET binding factor 2

Network of associatons between targets according to the STRING database.

First level regulatory network of nrf1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 8.5 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
1.3 6.4 GO:0070986 left/right axis specification(GO:0070986)
1.1 6.8 GO:0060251 regulation of glial cell proliferation(GO:0060251)
0.9 5.3 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.8 2.4 GO:0021531 spinal cord radial glial cell differentiation(GO:0021531)
0.7 2.1 GO:2000405 response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869) negative regulation of lymphocyte migration(GO:2000402) negative regulation of T cell migration(GO:2000405)
0.6 3.1 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.6 1.9 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.6 1.8 GO:0048205 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.5 2.1 GO:2000660 regulation of interleukin-1-mediated signaling pathway(GO:2000659) negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.5 5.3 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.5 3.6 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.5 1.5 GO:0002940 tRNA N2-guanine methylation(GO:0002940)
0.5 2.5 GO:0072104 renal system vasculature morphogenesis(GO:0061438) kidney vasculature morphogenesis(GO:0061439) glomerulus vasculature morphogenesis(GO:0072103) glomerular capillary formation(GO:0072104)
0.5 2.4 GO:0098881 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.5 3.3 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.5 2.4 GO:0060368 regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060368)
0.5 1.4 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.4 2.2 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.4 2.4 GO:0048011 neurotrophin TRK receptor signaling pathway(GO:0048011)
0.4 1.6 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.4 1.8 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.4 1.5 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.3 2.1 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.3 1.0 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
0.3 1.0 GO:0006409 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.3 1.6 GO:0001961 positive regulation of cytokine-mediated signaling pathway(GO:0001961) positive regulation of response to cytokine stimulus(GO:0060760)
0.3 0.9 GO:1904983 transmembrane glycine transport from cytosol to mitochondrion(GO:1904983)
0.3 2.0 GO:0007589 body fluid secretion(GO:0007589)
0.3 0.8 GO:0070417 cellular response to cold(GO:0070417)
0.3 4.4 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.3 0.8 GO:0009193 ribonucleoside diphosphate catabolic process(GO:0009191) pyrimidine ribonucleoside diphosphate metabolic process(GO:0009193) UDP metabolic process(GO:0046048)
0.3 1.8 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.2 3.5 GO:0009086 methionine biosynthetic process(GO:0009086)
0.2 2.1 GO:2000758 positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.2 1.4 GO:0070813 hydrogen sulfide metabolic process(GO:0070813)
0.2 7.0 GO:0031629 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.2 1.4 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.2 0.7 GO:2000055 positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000055)
0.2 1.5 GO:0032185 septin ring organization(GO:0031106) septin cytoskeleton organization(GO:0032185)
0.2 3.9 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.2 1.4 GO:0045901 positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.2 1.2 GO:0090342 regulation of cell aging(GO:0090342)
0.2 0.7 GO:0061015 RNA import into nucleus(GO:0006404) snRNA import into nucleus(GO:0061015)
0.2 1.7 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.2 0.6 GO:1905048 regulation of metallopeptidase activity(GO:1905048)
0.2 4.8 GO:0006446 regulation of translational initiation(GO:0006446)
0.2 0.3 GO:0002468 dendritic cell antigen processing and presentation(GO:0002468)
0.2 0.7 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.2 1.1 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.2 1.5 GO:0030104 water homeostasis(GO:0030104)
0.2 0.8 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.2 0.6 GO:0006272 leading strand elongation(GO:0006272)
0.1 2.4 GO:0015693 magnesium ion transport(GO:0015693)
0.1 2.3 GO:0051443 positive regulation of ubiquitin-protein transferase activity(GO:0051443)
0.1 1.8 GO:0009435 NAD biosynthetic process(GO:0009435)
0.1 3.4 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.1 0.7 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.1 0.4 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.1 1.3 GO:0070977 ossification involved in bone maturation(GO:0043931) bone maturation(GO:0070977)
0.1 0.9 GO:0030194 positive regulation of blood coagulation(GO:0030194) positive regulation of coagulation(GO:0050820) positive regulation of hemostasis(GO:1900048)
0.1 1.9 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.1 0.4 GO:0001207 histone displacement(GO:0001207) regulation of transcription involved in meiotic cell cycle(GO:0051037) positive regulation of transcription involved in meiotic cell cycle(GO:0051039)
0.1 0.5 GO:0021755 eurydendroid cell differentiation(GO:0021755)
0.1 0.8 GO:0006621 protein retention in ER lumen(GO:0006621)
0.1 1.3 GO:0035283 central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.1 1.2 GO:0045444 fat cell differentiation(GO:0045444)
0.1 1.0 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.1 1.5 GO:0042572 retinol metabolic process(GO:0042572)
0.1 0.7 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.1 0.9 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.1 0.9 GO:0071816 tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.1 0.3 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.1 1.0 GO:0043981 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.1 0.6 GO:0006013 mannose metabolic process(GO:0006013)
0.1 2.5 GO:0009408 response to heat(GO:0009408)
0.1 1.1 GO:0034312 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.1 3.2 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.1 1.0 GO:0043490 acidic amino acid transport(GO:0015800) aspartate transport(GO:0015810) L-glutamate transport(GO:0015813) malate-aspartate shuttle(GO:0043490)
0.1 1.5 GO:0055117 regulation of cardiac muscle contraction(GO:0055117)
0.1 0.5 GO:0060544 regulation of necrotic cell death(GO:0010939) regulation of necroptotic process(GO:0060544)
0.1 0.3 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.1 0.6 GO:0070189 kynurenine metabolic process(GO:0070189)
0.1 0.7 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.1 1.9 GO:0070654 sensory epithelium regeneration(GO:0070654) epithelium regeneration(GO:1990399)
0.1 0.4 GO:0006844 acyl carnitine transport(GO:0006844)
0.1 1.3 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.1 2.3 GO:0043249 erythrocyte maturation(GO:0043249)
0.1 2.4 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.1 0.9 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.1 0.7 GO:0033015 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.1 0.4 GO:0046929 negative regulation of neurotransmitter secretion(GO:0046929) response to cAMP(GO:0051591) cellular response to cAMP(GO:0071320) negative regulation of synaptic vesicle transport(GO:1902804) negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.1 0.4 GO:0006266 DNA ligation(GO:0006266) DNA ligation involved in DNA repair(GO:0051103)
0.1 1.8 GO:0005979 regulation of glycogen biosynthetic process(GO:0005979) regulation of glucan biosynthetic process(GO:0010962)
0.1 0.5 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.1 1.9 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.1 2.2 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.1 0.4 GO:1901909 diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.1 0.5 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.1 6.9 GO:0032272 negative regulation of actin filament polymerization(GO:0030837) negative regulation of protein polymerization(GO:0032272)
0.1 0.7 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.1 2.2 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.1 0.5 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.1 1.3 GO:0008354 germ cell migration(GO:0008354)
0.1 1.3 GO:0071436 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.1 0.9 GO:0002574 thrombocyte differentiation(GO:0002574)
0.1 2.1 GO:0030488 tRNA methylation(GO:0030488)
0.1 0.8 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.1 0.6 GO:0051601 exocyst localization(GO:0051601)
0.1 1.2 GO:0019471 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471)
0.1 3.1 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.1 0.9 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.1 2.9 GO:0006400 tRNA modification(GO:0006400)
0.1 0.7 GO:0031111 negative regulation of microtubule depolymerization(GO:0007026) negative regulation of microtubule polymerization or depolymerization(GO:0031111)
0.1 1.2 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.1 4.6 GO:0006413 translational initiation(GO:0006413)
0.1 0.2 GO:0015884 folic acid transport(GO:0015884) drug transport(GO:0015893) methotrexate transport(GO:0051958) reduced folate transmembrane transport(GO:0098838)
0.1 1.7 GO:0036297 interstrand cross-link repair(GO:0036297)
0.1 0.2 GO:0003222 ventricular trabecula myocardium morphogenesis(GO:0003222)
0.1 0.5 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.1 2.5 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.1 0.7 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.1 1.2 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.0 2.3 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.0 1.0 GO:0043507 activation of JUN kinase activity(GO:0007257) positive regulation of JUN kinase activity(GO:0043507)
0.0 1.8 GO:0008299 isoprenoid biosynthetic process(GO:0008299)
0.0 4.2 GO:0008654 phospholipid biosynthetic process(GO:0008654)
0.0 0.6 GO:0042694 muscle cell fate specification(GO:0042694)
0.0 1.3 GO:0032482 Rab protein signal transduction(GO:0032482)
0.0 0.4 GO:0019885 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 0.8 GO:2001235 positive regulation of apoptotic signaling pathway(GO:2001235)
0.0 1.7 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 3.0 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 0.6 GO:0008089 anterograde axonal transport(GO:0008089)
0.0 0.5 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277) intestinal epithelial structure maintenance(GO:0060729)
0.0 1.2 GO:0016180 snRNA processing(GO:0016180)
0.0 1.0 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 1.4 GO:0060037 pharyngeal system development(GO:0060037)
0.0 0.9 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.0 0.7 GO:0048264 determination of ventral identity(GO:0048264)
0.0 0.3 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.2 GO:0034427 nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'(GO:0034427)
0.0 2.8 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 1.1 GO:0031124 mRNA 3'-end processing(GO:0031124)
0.0 1.7 GO:0048484 enteric nervous system development(GO:0048484)
0.0 0.7 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 1.6 GO:0008033 tRNA processing(GO:0008033)
0.0 0.5 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 1.4 GO:0043277 apoptotic cell clearance(GO:0043277)
0.0 0.1 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.0 0.2 GO:1902624 positive regulation of neutrophil migration(GO:1902624)
0.0 1.3 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 0.5 GO:0031398 positive regulation of protein ubiquitination(GO:0031398)
0.0 7.9 GO:0043087 regulation of GTPase activity(GO:0043087)
0.0 0.4 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.4 GO:0035196 production of miRNAs involved in gene silencing by miRNA(GO:0035196)
0.0 1.4 GO:0030336 negative regulation of cell migration(GO:0030336)
0.0 0.2 GO:0006465 signal peptide processing(GO:0006465)
0.0 3.0 GO:0050684 regulation of mRNA processing(GO:0050684)
0.0 2.5 GO:0001756 somitogenesis(GO:0001756)
0.0 1.8 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.0 1.1 GO:0043523 regulation of neuron apoptotic process(GO:0043523)
0.0 1.3 GO:0051607 defense response to virus(GO:0051607)
0.0 1.0 GO:0038127 ERBB signaling pathway(GO:0038127)
0.0 0.5 GO:0048634 regulation of muscle organ development(GO:0048634)
0.0 1.5 GO:0060215 primitive hemopoiesis(GO:0060215)
0.0 0.4 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.0 0.7 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 0.4 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.5 GO:0042476 odontogenesis(GO:0042476)
0.0 2.4 GO:0006821 chloride transport(GO:0006821)
0.0 1.3 GO:0042074 cell migration involved in gastrulation(GO:0042074)
0.0 2.9 GO:0000377 RNA splicing, via transesterification reactions(GO:0000375) RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.0 1.6 GO:0071466 cellular response to xenobiotic stimulus(GO:0071466)
0.0 0.2 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.3 GO:0021986 habenula development(GO:0021986)
0.0 1.0 GO:0033339 pectoral fin development(GO:0033339)
0.0 1.0 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 0.7 GO:0061515 myeloid cell development(GO:0061515)
0.0 0.2 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.0 2.0 GO:0006338 chromatin remodeling(GO:0006338)
0.0 1.3 GO:0008285 negative regulation of cell proliferation(GO:0008285)
0.0 0.3 GO:0001569 patterning of blood vessels(GO:0001569)
0.0 0.7 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 0.5 GO:0030010 establishment of cell polarity(GO:0030010)
0.0 0.6 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.4 GO:0006368 transcription elongation from RNA polymerase II promoter(GO:0006368)
0.0 1.5 GO:0006457 protein folding(GO:0006457)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 5.8 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.8 2.4 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.5 3.1 GO:0008385 IkappaB kinase complex(GO:0008385)
0.5 3.6 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.5 1.9 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.4 2.1 GO:0031415 NatA complex(GO:0031415)
0.4 1.1 GO:0089701 U2AF(GO:0089701)
0.4 2.9 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.3 1.0 GO:0034456 CURI complex(GO:0032545) UTP-C complex(GO:0034456)
0.3 1.3 GO:0046695 SLIK (SAGA-like) complex(GO:0046695)
0.3 1.5 GO:0031414 N-terminal protein acetyltransferase complex(GO:0031414)
0.3 5.8 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.3 1.7 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.3 1.9 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.3 2.2 GO:0090576 transcription factor TFIIIB complex(GO:0000126) RNA polymerase III transcription factor complex(GO:0090576)
0.3 0.8 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.2 2.5 GO:0030904 retromer complex(GO:0030904)
0.2 1.5 GO:0005826 actomyosin contractile ring(GO:0005826)
0.2 1.0 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.2 1.5 GO:0070847 core mediator complex(GO:0070847)
0.2 0.8 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.2 4.3 GO:0071004 U2-type prespliceosome(GO:0071004) prespliceosome(GO:0071010)
0.2 1.6 GO:0016272 prefoldin complex(GO:0016272)
0.2 1.3 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.2 4.0 GO:0071565 nBAF complex(GO:0071565)
0.2 1.0 GO:0071986 Ragulator complex(GO:0071986)
0.2 1.7 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.2 1.7 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1 1.6 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 0.6 GO:0097134 cyclin E1-CDK2 complex(GO:0097134)
0.1 0.6 GO:1990909 Wnt signalosome(GO:1990909)
0.1 2.0 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 0.7 GO:0045273 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.1 1.5 GO:0016580 Sin3 complex(GO:0016580)
0.1 2.3 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.1 0.9 GO:0071818 BAT3 complex(GO:0071818)
0.1 1.3 GO:0090533 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
0.1 6.5 GO:0005811 lipid particle(GO:0005811)
0.1 1.1 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.1 0.7 GO:0005915 cell-cell adherens junction(GO:0005913) zonula adherens(GO:0005915)
0.1 2.4 GO:0045180 basal cortex(GO:0045180)
0.1 1.8 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 3.0 GO:0035861 site of double-strand break(GO:0035861)
0.1 3.9 GO:0016605 PML body(GO:0016605)
0.1 0.9 GO:0070652 HAUS complex(GO:0070652)
0.1 2.4 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.1 1.2 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.1 0.9 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.1 0.8 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024) nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.1 1.5 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 1.4 GO:0000813 ESCRT I complex(GO:0000813)
0.1 3.4 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1 0.7 GO:0036449 microtubule minus-end(GO:0036449)
0.1 0.5 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)
0.1 4.8 GO:0031201 SNARE complex(GO:0031201)
0.1 0.3 GO:0071012 U2-type catalytic step 1 spliceosome(GO:0071006) catalytic step 1 spliceosome(GO:0071012)
0.1 3.5 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 1.0 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.1 2.3 GO:0042734 presynaptic membrane(GO:0042734)
0.1 0.4 GO:0030891 VCB complex(GO:0030891)
0.1 0.2 GO:0055087 Ski complex(GO:0055087)
0.1 1.2 GO:0032039 integrator complex(GO:0032039)
0.1 1.4 GO:0071141 SMAD protein complex(GO:0071141)
0.1 0.8 GO:0030663 COPI-coated vesicle membrane(GO:0030663)
0.1 0.2 GO:0098553 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.1 1.3 GO:0035102 PRC1 complex(GO:0035102)
0.1 3.1 GO:0048786 presynaptic active zone(GO:0048786)
0.0 1.1 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.8 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.8 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.3 GO:0032797 SMN complex(GO:0032797)
0.0 1.1 GO:0005876 spindle microtubule(GO:0005876)
0.0 2.4 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.4 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 1.5 GO:0043204 perikaryon(GO:0043204)
0.0 0.5 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 5.3 GO:0031227 intrinsic component of endoplasmic reticulum membrane(GO:0031227)
0.0 0.4 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 6.8 GO:0010008 endosome membrane(GO:0010008)
0.0 3.6 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.0 1.4 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.2 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.7 GO:0005844 polysome(GO:0005844)
0.0 0.5 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 10.3 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 1.5 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 2.3 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 2.3 GO:0016459 myosin complex(GO:0016459)
0.0 0.2 GO:0035101 FACT complex(GO:0035101)
0.0 0.4 GO:0046930 pore complex(GO:0046930)
0.0 0.4 GO:0000145 exocyst(GO:0000145)
0.0 0.5 GO:0000781 chromosome, telomeric region(GO:0000781)
0.0 0.7 GO:0030173 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 0.2 GO:0005868 cytoplasmic dynein complex(GO:0005868)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.8 8.5 GO:0008386 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
1.1 5.7 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184) 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.8 3.1 GO:0008384 IkappaB kinase activity(GO:0008384)
0.7 2.2 GO:0071077 coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.7 2.1 GO:1990715 mRNA CDS binding(GO:1990715)
0.6 1.7 GO:0004394 heparan sulfate 2-O-sulfotransferase activity(GO:0004394)
0.5 4.8 GO:0008494 translation activator activity(GO:0008494)
0.4 1.3 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.4 3.5 GO:0031419 cobalamin binding(GO:0031419)
0.4 4.4 GO:0035198 miRNA binding(GO:0035198)
0.4 3.6 GO:0008420 CTD phosphatase activity(GO:0008420)
0.4 3.5 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.4 1.5 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.3 1.4 GO:0008488 gamma-glutamyl carboxylase activity(GO:0008488)
0.3 5.1 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.3 1.3 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.3 2.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.3 1.7 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.3 0.8 GO:0046923 ER retention sequence binding(GO:0046923)
0.3 3.6 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.3 3.5 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.3 1.1 GO:0102344 3-hydroxyacyl-CoA dehydratase activity(GO:0018812) 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.3 1.6 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.3 5.2 GO:0030515 snoRNA binding(GO:0030515)
0.2 1.9 GO:0051219 protein phosphorylated amino acid binding(GO:0045309) phosphoprotein binding(GO:0051219)
0.2 4.8 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.2 3.6 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.2 0.7 GO:0000104 succinate dehydrogenase activity(GO:0000104)
0.2 3.1 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.2 1.0 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.2 0.6 GO:0047804 cysteine-S-conjugate beta-lyase activity(GO:0047804)
0.2 1.3 GO:0048019 receptor antagonist activity(GO:0048019)
0.2 1.0 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.2 1.1 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 1.5 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.1 2.1 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 0.4 GO:1901612 cardiolipin binding(GO:1901612)
0.1 0.4 GO:0003909 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.1 0.9 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.1 9.0 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 0.8 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.1 3.3 GO:0005246 calcium channel regulator activity(GO:0005246)
0.1 1.0 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1 1.8 GO:2001069 glycogen binding(GO:2001069)
0.1 2.2 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 0.3 GO:0008119 thiopurine S-methyltransferase activity(GO:0008119)
0.1 2.0 GO:0070566 adenylyltransferase activity(GO:0070566)
0.1 0.9 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 1.1 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.1 0.9 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.1 1.6 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 1.2 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.1 2.4 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 1.9 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 2.6 GO:0034062 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.1 1.3 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 1.5 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1 2.4 GO:0005112 Notch binding(GO:0005112)
0.1 0.5 GO:0050699 WW domain binding(GO:0050699)
0.1 0.4 GO:0015227 acyl carnitine transmembrane transporter activity(GO:0015227)
0.1 2.4 GO:0042577 lipid phosphatase activity(GO:0042577)
0.1 1.8 GO:0097602 cullin family protein binding(GO:0097602)
0.1 1.4 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.1 1.7 GO:0016251 obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.1 6.9 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1 1.0 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.1 0.4 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 2.8 GO:0035064 methylated histone binding(GO:0035064)
0.1 1.1 GO:0043028 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.1 0.4 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.1 1.0 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 0.5 GO:0034057 RNA strand annealing activity(GO:0033592) RNA strand-exchange activity(GO:0034057)
0.1 0.4 GO:0015288 porin activity(GO:0015288)
0.1 1.8 GO:0031267 small GTPase binding(GO:0031267)
0.1 1.6 GO:0051011 microtubule minus-end binding(GO:0051011)
0.1 0.4 GO:0000298 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.1 0.7 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 1.3 GO:0001671 ATPase activator activity(GO:0001671)
0.1 0.3 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.1 1.8 GO:0004659 prenyltransferase activity(GO:0004659)
0.1 0.9 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.1 3.2 GO:0031072 heat shock protein binding(GO:0031072)
0.1 0.6 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 3.0 GO:0003725 double-stranded RNA binding(GO:0003725)
0.1 1.9 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 1.6 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 0.2 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.1 0.3 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.1 2.9 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.1 1.3 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 2.2 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.1 0.2 GO:0015350 reduced folate carrier activity(GO:0008518) methotrexate transporter activity(GO:0015350)
0.1 3.1 GO:0030170 pyridoxal phosphate binding(GO:0030170)
0.1 0.6 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.1 5.8 GO:0019208 phosphatase regulator activity(GO:0019208)
0.0 0.8 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.7 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 4.2 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.8 GO:0045134 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.0 1.2 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.4 GO:0070628 proteasome binding(GO:0070628)
0.0 1.1 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 1.2 GO:0004812 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 0.5 GO:0004046 aminoacylase activity(GO:0004046)
0.0 1.2 GO:0016891 endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891)
0.0 0.3 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 2.0 GO:0016859 peptidyl-prolyl cis-trans isomerase activity(GO:0003755) cis-trans isomerase activity(GO:0016859)
0.0 0.6 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 3.6 GO:0004519 endonuclease activity(GO:0004519)
0.0 1.6 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.4 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.0 7.0 GO:0042393 histone binding(GO:0042393)
0.0 0.9 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 8.9 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.0 0.3 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 1.9 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 1.6 GO:0043022 ribosome binding(GO:0043022)
0.0 0.5 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0 1.0 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 1.3 GO:0004707 MAP kinase activity(GO:0004707)
0.0 2.5 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 12.3 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.7 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.1 GO:0033149 FFAT motif binding(GO:0033149)
0.0 0.5 GO:0005123 death receptor binding(GO:0005123)
0.0 0.2 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.8 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 3.6 GO:0004713 protein tyrosine kinase activity(GO:0004713)
0.0 0.6 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.2 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.2 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.7 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0 0.7 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.2 GO:0022884 protein transmembrane transporter activity(GO:0008320) macromolecule transmembrane transporter activity(GO:0022884)
0.0 0.1 GO:0016972 thiol oxidase activity(GO:0016972)
0.0 7.2 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.2 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.2 GO:0004477 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
0.0 3.1 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.6 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 5.3 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 0.4 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.0 0.2 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.0 0.1 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 2.4 GO:0008134 transcription factor binding(GO:0008134)
0.0 0.1 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 10.7 GO:0008270 zinc ion binding(GO:0008270)
0.0 0.6 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 1.2 GO:0019904 protein domain specific binding(GO:0019904)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.3 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.2 3.1 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.2 5.0 PID BARD1 PATHWAY BARD1 signaling events
0.1 1.2 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 1.8 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.1 0.7 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.1 3.6 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.1 3.6 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.1 0.7 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.1 3.3 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.1 1.2 PID EPHB FWD PATHWAY EPHB forward signaling
0.1 3.2 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 1.0 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 0.8 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 0.5 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.7 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.6 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 1.4 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.5 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.5 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 0.6 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 0.5 PID P75 NTR PATHWAY p75(NTR)-mediated signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 8.5 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.7 5.7 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.5 2.4 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.3 3.1 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.2 0.7 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.2 4.9 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.2 3.3 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.2 1.6 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.2 1.4 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 2.5 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.1 2.5 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 1.2 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.1 1.0 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 0.7 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.1 2.1 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.1 1.7 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.1 3.9 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.1 2.1 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.1 1.8 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 5.2 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.1 3.2 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1 2.1 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.1 1.3 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 1.7 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.1 3.2 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 1.6 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.1 1.3 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.5 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.7 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.6 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 1.0 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.4 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 1.2 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.7 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.5 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 1.3 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 1.4 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.7 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 2.5 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.7 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.4 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.0 1.1 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.7 REACTOME UNFOLDED PROTEIN RESPONSE Genes involved in Unfolded Protein Response
0.0 0.3 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.4 REACTOME GLOBAL GENOMIC NER GG NER Genes involved in Global Genomic NER (GG-NER)
0.0 0.3 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 2.1 REACTOME FATTY ACID TRIACYLGLYCEROL AND KETONE BODY METABOLISM Genes involved in Fatty acid, triacylglycerol, and ketone body metabolism
0.0 0.9 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.3 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.2 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.2 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation