Project

PRJNA438478: RNAseq of wild type zebrafish germline

Navigation
Downloads

Results for olig3_olig2+olig4_olig1

Z-value: 1.85

Motif logo

logo of logo of logo of

Transcription factors associated with olig3_olig2+olig4_olig1

Gene Symbol Gene ID Gene Info
olig3
ENSDARG00000074253 oligodendrocyte transcription factor 3
olig2
ENSDARG00000040946 oligodendrocyte lineage transcription factor 2
olig4
ENSDARG00000052610 oligodendrocyte transcription factor 4
olig4
ENSDARG00000116678 oligodendrocyte transcription factor 4
olig1
ENSDARG00000040948 oligodendrocyte transcription factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
olig4dr11_v1_chr13_+_45967179_45967179-0.924.7e-08Click!
olig1dr11_v1_chr9_-_32730487_32730487-0.522.7e-02Click!
olig2dr11_v1_chr9_-_32753535_32753535-0.312.2e-01Click!

Activity profile of olig3_olig2+olig4_olig1 motif

Sorted Z-values of olig3_olig2+olig4_olig1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr7_+_46020508 6.83 ENSDART00000170294
ccne1
cyclin E1
chr1_-_43712120 6.62 ENSDART00000074600
SLC9B2
si:dkey-162b23.4
chr16_-_39267185 6.22 ENSDART00000058550
ENSDART00000133642
gpd1l
glycerol-3-phosphate dehydrogenase 1 like
chr12_-_17863467 6.16 ENSDART00000042006
baiap2l1a
BAI1-associated protein 2-like 1a
chr17_-_15189397 5.57 ENSDART00000133710
ENSDART00000110507
wdhd1
WD repeat and HMG-box DNA binding protein 1
chr19_-_8798178 5.49 ENSDART00000188232
cers2a
ceramide synthase 2a
chr18_-_40708537 5.25 ENSDART00000077577
si:ch211-132b12.8
si:ch211-132b12.8
chr8_+_1009831 5.03 ENSDART00000172414
fabp1b.2
fatty acid binding protein 1b, liver, tandem duplicate 2
chr19_-_12212692 4.49 ENSDART00000142077
ENSDART00000151599
ENSDART00000140834
ENSDART00000078781
znf706
zinc finger protein 706
chr3_+_43374571 4.33 ENSDART00000182497
zfand2a
zinc finger, AN1-type domain 2A
chr20_+_52529044 4.30 ENSDART00000158230
ENSDART00000002787
pycr3
pyrroline-5-carboxylate reductase 3
chr20_-_4031475 4.25 ENSDART00000112053
fam89a
family with sequence similarity 89, member A
chr6_-_7749396 4.08 ENSDART00000105232
myh9a
myosin, heavy chain 9a, non-muscle
chr9_-_6502491 4.07 ENSDART00000102672
nck2a
NCK adaptor protein 2a
chr19_-_23249822 4.02 ENSDART00000140665
grb10a
growth factor receptor-bound protein 10a
chr3_+_43373867 3.88 ENSDART00000159455
ENSDART00000172425
zfand2a
zinc finger, AN1-type domain 2A
chr20_+_33924235 3.86 ENSDART00000146292
ENSDART00000139609
lmx1a
LIM homeobox transcription factor 1, alpha
chr2_-_39036604 3.71 ENSDART00000129963
rbp1
retinol binding protein 1b, cellular
chr20_-_31252809 3.68 ENSDART00000137236
hpcal1
hippocalcin-like 1
chr13_+_11550454 3.62 ENSDART00000034935
ENSDART00000166908
desi2
desumoylating isopeptidase 2
chr17_-_17756344 3.42 ENSDART00000190146
adck1
aarF domain containing kinase 1
chr19_+_38167468 3.41 ENSDART00000160756
phf14
PHD finger protein 14
chr3_+_7763114 3.37 ENSDART00000057434
hook2
hook microtubule-tethering protein 2
chr7_+_9290929 3.33 ENSDART00000128530
snrpa1
small nuclear ribonucleoprotein polypeptide A'
chr17_-_15188440 3.29 ENSDART00000151885
wdhd1
WD repeat and HMG-box DNA binding protein 1
chr7_+_46019780 3.26 ENSDART00000163991
ccne1
cyclin E1
chr5_+_28259655 3.25 ENSDART00000087684
ncaph
non-SMC condensin I complex, subunit H
chr20_-_23876291 3.20 ENSDART00000043316
katna1
katanin p60 (ATPase containing) subunit A 1
chr3_+_43774369 3.19 ENSDART00000157964
zc3h7a
zinc finger CCCH-type containing 7A
chr3_+_19665319 3.19 ENSDART00000007857
ENSDART00000193509
mettl2a
methyltransferase like 2A
chr19_-_27578929 3.18 ENSDART00000177368
si:dkeyp-46h3.3
si:dkeyp-46h3.3
chr16_-_8132742 3.18 ENSDART00000104323
snrka
SNF related kinase a
chr24_+_7741521 3.16 ENSDART00000009687
zgc:56095
zgc:56095
chr2_+_1988036 3.12 ENSDART00000155956
ssx2ipa
synovial sarcoma, X breakpoint 2 interacting protein a
chr14_+_35405518 3.11 ENSDART00000171565
zbtb3
zinc finger and BTB domain containing 3
chr5_-_25576462 2.97 ENSDART00000165147
si:dkey-229d2.4
si:dkey-229d2.4
chr5_-_29512538 2.96 ENSDART00000098364
ehmt1a
euchromatic histone-lysine N-methyltransferase 1a
chr5_-_22602979 2.95 ENSDART00000146287
nono
non-POU domain containing, octamer-binding
chr2_-_42558549 2.91 ENSDART00000025997
dip2cb
disco-interacting protein 2 homolog Cb
chr1_+_40613297 2.88 ENSDART00000040798
ENSDART00000168067
ENSDART00000130490
naa15b
N(alpha)-acetyltransferase 15, NatA auxiliary subunit b
chr9_+_8364553 2.87 ENSDART00000190713
si:dkey-90l23.2
si:dkey-90l23.2
chr20_-_34028967 2.86 ENSDART00000153408
ENSDART00000033817
scyl3
SCY1-like, kinase-like 3
chr24_-_16980337 2.81 ENSDART00000183812
klhl15
kelch-like family member 15
chr10_-_26225548 2.80 ENSDART00000132019
ENSDART00000079194
arfip2b
ADP-ribosylation factor interacting protein 2b
chr5_+_37379825 2.80 ENSDART00000171826
klhl13
kelch-like family member 13
chr22_-_11054244 2.78 ENSDART00000105823
insrb
insulin receptor b
chr2_-_10943093 2.77 ENSDART00000148999
ssbp3a
single stranded DNA binding protein 3a
chr19_+_7173613 2.74 ENSDART00000001331
hsd17b8
hydroxysteroid (17-beta) dehydrogenase 8
chr24_-_41797681 2.71 ENSDART00000169643
arhgap28
Rho GTPase activating protein 28
chr19_+_24324967 2.66 ENSDART00000090081
sema4ab
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4Ab
chr19_+_9113932 2.63 ENSDART00000060442
setdb1a
SET domain, bifurcated 1a
chr9_+_28150275 2.60 ENSDART00000192129
plekhm3
pleckstrin homology domain containing, family M, member 3
chr1_+_16600690 2.57 ENSDART00000162164
mtus1b
microtubule associated tumor suppressor 1b
chr8_+_47219107 2.56 ENSDART00000146018
ENSDART00000075068
mthfr
methylenetetrahydrofolate reductase (NAD(P)H)
chr13_+_22731356 2.56 ENSDART00000133064
nfkb2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr5_-_32505276 2.55 ENSDART00000034705
ENSDART00000187597
ntmt1
N-terminal Xaa-Pro-Lys N-methyltransferase 1
chr14_-_34633960 2.52 ENSDART00000128869
ENSDART00000179977
afap1l1a
actin filament associated protein 1-like 1a
chr18_-_3520358 2.50 ENSDART00000181412
capn5a
calpain 5a
chr13_+_11439486 2.47 ENSDART00000138312
zbtb18
zinc finger and BTB domain containing 18
chr13_+_21676235 2.46 ENSDART00000137804
ENSDART00000134950
ENSDART00000129653
mtg1
mitochondrial ribosome-associated GTPase 1
chr20_-_14781904 2.37 ENSDART00000187200
ENSDART00000179912
ENSDART00000160481
ENSDART00000026969
suco
SUN domain containing ossification factor
chr20_+_28803642 2.35 ENSDART00000188526
fntb
farnesyltransferase, CAAX box, beta
chr15_+_4988189 2.35 ENSDART00000142995
ENSDART00000062852
spcs2
signal peptidase complex subunit 2
chr11_+_25693395 2.34 ENSDART00000110224
mon1bb
MON1 secretory trafficking family member Bb
chr25_-_37338048 2.33 ENSDART00000073439
trim44
tripartite motif containing 44
chr21_+_13387965 2.33 ENSDART00000134347
zgc:113162
zgc:113162
chr3_-_27647845 2.32 ENSDART00000151625
si:ch211-157c3.4
si:ch211-157c3.4
chr10_-_4961923 2.31 ENSDART00000050177
ENSDART00000146066
snx30
sorting nexin family member 30
chr23_-_4019699 2.29 ENSDART00000159780
slc9a8
solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
chr9_-_11676491 2.27 ENSDART00000022358
zc3h15
zinc finger CCCH-type containing 15
chr23_-_18057270 2.26 ENSDART00000173385
zgc:92287
zgc:92287
chr14_+_31618982 2.26 ENSDART00000026195
slc9a6a
solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6a
chr1_-_22652424 2.23 ENSDART00000036797
uchl1
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr7_+_38667066 2.23 ENSDART00000013394
mtch2
mitochondrial carrier homolog 2
chr19_-_7406933 2.22 ENSDART00000151137
oxr1b
oxidation resistance 1b
chr20_+_34390196 2.21 ENSDART00000183596
trmt1l
tRNA methyltransferase 1-like
chr8_-_51507144 2.19 ENSDART00000024882
ENSDART00000135166
fgfr1a
fibroblast growth factor receptor 1a
chr1_+_49415281 2.17 ENSDART00000015007
taf5
TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr13_+_15581270 2.16 ENSDART00000189880
ENSDART00000190067
ENSDART00000041293
mark3a
MAP/microtubule affinity-regulating kinase 3a
chr9_-_25328527 2.13 ENSDART00000060840
med4
mediator complex subunit 4
chr13_+_30421472 2.11 ENSDART00000143569
zmiz1a
zinc finger, MIZ-type containing 1a
chr13_+_22698215 2.09 ENSDART00000137467
si:ch211-134m17.9
si:ch211-134m17.9
chr22_-_14272699 2.07 ENSDART00000190121
si:ch211-246m6.5
si:ch211-246m6.5
chr16_-_17200120 2.07 ENSDART00000147739
gapdh
glyceraldehyde-3-phosphate dehydrogenase
chr24_-_10828560 2.03 ENSDART00000132282
fam49bb
family with sequence similarity 49, member Bb
chr19_+_10661520 2.01 ENSDART00000091813
ENSDART00000165653
ago3b
argonaute RISC catalytic component 3b
chr8_+_36582728 2.00 ENSDART00000049230
pqbp1
polyglutamine binding protein 1
chr19_-_46037835 1.99 ENSDART00000163815
nup153
nucleoporin 153
chr1_+_19649545 1.97 ENSDART00000054575
tmem192
transmembrane protein 192
chr11_-_279328 1.96 ENSDART00000066179
npffl
neuropeptide FF-amide peptide precursor like
chr13_+_9368621 1.96 ENSDART00000109126
alms1
Alstrom syndrome protein 1
chr12_-_9498060 1.94 ENSDART00000160622
si:ch211-207i20.2
si:ch211-207i20.2
chr19_+_32456974 1.93 ENSDART00000088265
atxn1a
ataxin 1a
chr2_-_45154550 1.91 ENSDART00000148595
ENSDART00000150002
capn10
calpain 10
chr10_-_32465462 1.91 ENSDART00000134056
uvrag
UV radiation resistance associated gene
chr16_-_17586883 1.89 ENSDART00000017142
m6pr
mannose-6-phosphate receptor (cation dependent)
chr18_-_40913294 1.89 ENSDART00000059196
ENSDART00000098878
polr2i
polymerase (RNA) II (DNA directed) polypeptide I
chr22_-_8006342 1.89 ENSDART00000162028
sc:d217
sc:d217
chr15_-_28587490 1.87 ENSDART00000186196
ssh2a
slingshot protein phosphatase 2a
chr11_+_5588122 1.87 ENSDART00000113281
zgc:172302
zgc:172302
chr12_-_22355430 1.86 ENSDART00000153296
ENSDART00000056919
ENSDART00000159036
nsfb
N-ethylmaleimide-sensitive factor b
chr4_+_9178913 1.85 ENSDART00000168558
nfyba
nuclear transcription factor Y, beta a
chr24_-_16979728 1.85 ENSDART00000005331
klhl15
kelch-like family member 15
chr20_-_48898560 1.84 ENSDART00000163071
xrn2
5'-3' exoribonuclease 2
chr20_+_28803977 1.79 ENSDART00000153351
ENSDART00000038149
fntb
farnesyltransferase, CAAX box, beta
chr9_+_48123002 1.78 ENSDART00000099794
ENSDART00000169733
klhl23
kelch-like family member 23
chr6_-_42949184 1.76 ENSDART00000147208
edem1
ER degradation enhancer, mannosidase alpha-like 1
chr25_+_3294150 1.76 ENSDART00000030683
tmpob
thymopoietin b
chr13_-_51922290 1.75 ENSDART00000168648
srfb
serum response factor b
chr20_-_1265562 1.74 ENSDART00000189866
lats1
large tumor suppressor kinase 1
chr6_+_21992820 1.73 ENSDART00000147507
thumpd3
THUMP domain containing 3
chr25_+_19870603 1.73 ENSDART00000047251
gramd4b
GRAM domain containing 4b
chr5_-_39805874 1.72 ENSDART00000176202
ENSDART00000191683
rasgef1ba
RasGEF domain family, member 1Ba
chr23_-_31648026 1.71 ENSDART00000133569
sgk1
serum/glucocorticoid regulated kinase 1
chr15_-_28480546 1.71 ENSDART00000057696
ENSDART00000160858
git1
G protein-coupled receptor kinase interacting ArfGAP 1
chr14_+_10981703 1.70 ENSDART00000091169
abcb7
ATP-binding cassette, sub-family B (MDR/TAP), member 7
chr2_-_57110477 1.70 ENSDART00000181132
slc25a42
solute carrier family 25, member 42
chr17_-_8692722 1.69 ENSDART00000148931
ENSDART00000192891
ctbp2a
C-terminal binding protein 2a
chr21_-_2042037 1.68 ENSDART00000171131
ENSDART00000160144
add1
adducin 1 (alpha)
chr1_-_6028876 1.68 ENSDART00000168117
si:ch1073-345a8.1
si:ch1073-345a8.1
chr20_-_9123296 1.66 ENSDART00000188495
mysm1
Myb-like, SWIRM and MPN domains 1
chr17_-_45104750 1.66 ENSDART00000075520
aldh6a1
aldehyde dehydrogenase 6 family, member A1
chr9_-_30264415 1.66 ENSDART00000060150
mid1ip1a
MID1 interacting protein 1a
chr23_+_17522867 1.66 ENSDART00000002714
slc17a9b
solute carrier family 17 (vesicular nucleotide transporter), member 9b
chr16_+_53252951 1.64 ENSDART00000126543
si:ch211-269k10.5
si:ch211-269k10.5
chr3_+_25907266 1.64 ENSDART00000170324
ENSDART00000192633
tom1
target of myb1 membrane trafficking protein
chr2_+_24770435 1.63 ENSDART00000078854
mpv17l2
MPV17 mitochondrial membrane protein-like 2
chr2_+_44972720 1.63 ENSDART00000075146
alg3
asparagine-linked glycosylation 3 (alpha-1,3-mannosyltransferase)
chr3_-_26184018 1.61 ENSDART00000191604
si:ch211-11k18.4
si:ch211-11k18.4
chr17_-_43594864 1.60 ENSDART00000139980
zfyve28
zinc finger, FYVE domain containing 28
chr11_-_24532988 1.60 ENSDART00000067078
plekhg5a
pleckstrin homology domain containing, family G (with RhoGef domain) member 5a
chr15_-_43270889 1.60 ENSDART00000166805
serpine2
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
chr6_+_50393047 1.58 ENSDART00000055502
ENSDART00000055511
ergic3
ERGIC and golgi 3
chr19_+_42227400 1.57 ENSDART00000131574
ENSDART00000135436
jtb
jumping translocation breakpoint
chr5_-_57289872 1.55 ENSDART00000189893
ENSDART00000050957
fer
fer (fps/fes related) tyrosine kinase
chr18_+_6866276 1.55 ENSDART00000187516
dnaja2l
DnaJ (Hsp40) homolog, subfamily A, member 2, like
chr25_+_3104959 1.55 ENSDART00000167130
rab3il1
RAB3A interacting protein (rabin3)-like 1
chr5_+_50869091 1.55 ENSDART00000083294
nol6
nucleolar protein 6 (RNA-associated)
chr13_+_29926631 1.53 ENSDART00000135265
cuedc2
CUE domain containing 2
chr22_-_37797695 1.52 ENSDART00000085931
ENSDART00000185443
acap2
ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
chr23_+_7548797 1.52 ENSDART00000006765
tm9sf4
transmembrane 9 superfamily protein member 4
chr17_-_24820801 1.51 ENSDART00000156606
trmt61b
tRNA methyltransferase 61B
chr5_+_44805269 1.51 ENSDART00000136965
ctsla
cathepsin La
chr24_-_7777389 1.50 ENSDART00000138541
rpgrip1
RPGR interacting protein 1
chr3_-_54500354 1.49 ENSDART00000124215
trip10a
thyroid hormone receptor interactor 10a
chr12_-_3077395 1.49 ENSDART00000002867
ENSDART00000126315
rfng
RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr22_-_37796998 1.48 ENSDART00000124742
ENSDART00000191232
acap2
ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
chr9_-_32300783 1.48 ENSDART00000078596
hspd1
heat shock 60 protein 1
chr10_+_15025006 1.48 ENSDART00000145192
ENSDART00000140084
si:dkey-88l16.5
si:dkey-88l16.5
chr5_+_44805028 1.47 ENSDART00000141198
ctsla
cathepsin La
chr4_-_4592287 1.47 ENSDART00000155287
rassf3
Ras association (RalGDS/AF-6) domain family member 3
chr5_+_47882319 1.47 ENSDART00000149316
rasa1a
RAS p21 protein activator (GTPase activating protein) 1a
chr1_-_55263736 1.46 ENSDART00000152504
ENSDART00000152687
si:ch211-286b5.4
si:ch211-286b5.4
chr1_+_14454663 1.46 ENSDART00000005067
rbpja
recombination signal binding protein for immunoglobulin kappa J region a
chr5_+_52625975 1.46 ENSDART00000170341
ENSDART00000168317
apba1a
amyloid beta (A4) precursor protein-binding, family A, member 1a
chr6_+_23026170 1.44 ENSDART00000186683
srp68
signal recognition particle 68
chr7_-_24520866 1.44 ENSDART00000077039
faah2b
fatty acid amide hydrolase 2b
chr3_+_52953489 1.44 ENSDART00000125136
dsn1
DSN1 homolog, MIS12 kinetochore complex component
chr20_+_25486021 1.44 ENSDART00000063052
hook1
hook microtubule-tethering protein 1
chr8_-_53991184 1.44 ENSDART00000180675
SLC35E2
solute carrier family 35 member E2
chr14_-_33425170 1.44 ENSDART00000124629
ENSDART00000105800
ENSDART00000001318
nkap
NFKB activating protein
chr7_+_72630369 1.43 ENSDART00000170698
FO905040.1

chr1_+_39995008 1.43 ENSDART00000166251
aip
aryl hydrocarbon receptor interacting protein
chr17_+_15534815 1.42 ENSDART00000159426
marcksb
myristoylated alanine-rich protein kinase C substrate b
chr1_-_34450784 1.42 ENSDART00000140515
lmo7b
LIM domain 7b
chr17_+_28005763 1.42 ENSDART00000155838
luzp1
leucine zipper protein 1
chr5_+_20255568 1.42 ENSDART00000153643
ssh1a
slingshot protein phosphatase 1a
chr21_+_20386865 1.42 ENSDART00000144366
si:dkey-30k6.5
si:dkey-30k6.5
chr20_-_3997531 1.41 ENSDART00000092217
ttc13
tetratricopeptide repeat domain 13
chr21_+_974555 1.41 ENSDART00000130648
scarb2c
scavenger receptor class B, member 2c
chr24_-_9689915 1.40 ENSDART00000185972
ENSDART00000093046
uba5
ubiquitin-like modifier activating enzyme 5
chr13_-_29980215 1.40 ENSDART00000042049
hif1an
hypoxia inducible factor 1, alpha subunit inhibitor
chr1_-_34450622 1.37 ENSDART00000083736
lmo7b
LIM domain 7b
chr9_-_32300611 1.37 ENSDART00000127938
hspd1
heat shock 60 protein 1
chr20_-_43743700 1.36 ENSDART00000100620
si:dkeyp-50f7.2
si:dkeyp-50f7.2
chr24_-_26885897 1.36 ENSDART00000180512
fndc3bb
fibronectin type III domain containing 3Bb
chr20_+_54333774 1.36 ENSDART00000144633
cipcb
CLOCK-interacting pacemaker b
chr25_+_37397031 1.35 ENSDART00000193643
ENSDART00000169132
slc1a2b
solute carrier family 1 (glial high affinity glutamate transporter), member 2b
chr8_-_410728 1.35 ENSDART00000151255
trim36
tripartite motif containing 36
chr8_-_26792912 1.35 ENSDART00000139787
kazna
kazrin, periplakin interacting protein a
chr12_-_20616160 1.35 ENSDART00000105362
snx11
sorting nexin 11
chr19_+_42071033 1.34 ENSDART00000169067
ENSDART00000183436
nfyc
nuclear transcription factor Y, gamma
chr12_+_5048044 1.32 ENSDART00000161548
ENSDART00000172607
kif22
kinesin family member 22
chr5_+_44804791 1.32 ENSDART00000122288
ctsla
cathepsin La
chr24_-_21172122 1.32 ENSDART00000154259
atp6v1ab
ATPase H+ transporting V1 subunit Ab
chr24_-_9989634 1.32 ENSDART00000115275
zgc:152652
zgc:152652
chr9_-_43644261 1.31 ENSDART00000023684
cwc22
CWC22 spliceosome-associated protein homolog (S. cerevisiae)
chr14_-_47314011 1.31 ENSDART00000178523
fstl5
follistatin-like 5
chr2_-_4787566 1.30 ENSDART00000160663
ENSDART00000157808
tnk2b
tyrosine kinase, non-receptor, 2b
chr10_-_2942900 1.30 ENSDART00000002622
oclna
occludin a
chr10_+_18877362 1.29 ENSDART00000138334
ppp2r2ab
protein phosphatase 2, regulatory subunit B, alpha b
chr5_+_32817688 1.29 ENSDART00000139472
crata
carnitine O-acetyltransferase a
chr21_-_1635268 1.29 ENSDART00000151258
zgc:152948
zgc:152948
chr14_+_45028062 1.29 ENSDART00000184717
ENSDART00000185481
ATP8A1
ATPase phospholipid transporting 8A1
chr7_-_50410524 1.28 ENSDART00000083346
hypk
huntingtin interacting protein K
chr21_+_21195487 1.28 ENSDART00000181746
ENSDART00000184832
rictorb
RPTOR independent companion of MTOR, complex 2b
chr10_-_24759616 1.28 ENSDART00000079528
ilk
integrin-linked kinase
chr5_+_30518036 1.28 ENSDART00000161836
hmbsa
hydroxymethylbilane synthase a
chr1_-_18585046 1.27 ENSDART00000147228
fam114a1
family with sequence similarity 114, member A1
chr20_-_9123052 1.27 ENSDART00000125133
mysm1
Myb-like, SWIRM and MPN domains 1

Network of associatons between targets according to the STRING database.

First level regulatory network of olig3_olig2+olig4_olig1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 4.9 GO:0046168 NADH oxidation(GO:0006116) glycerol-3-phosphate catabolic process(GO:0046168)
1.0 4.1 GO:0018343 protein farnesylation(GO:0018343)
0.9 7.4 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.9 2.6 GO:0006480 N-terminal protein amino acid methylation(GO:0006480)
0.8 4.1 GO:0061439 renal system vasculature morphogenesis(GO:0061438) kidney vasculature morphogenesis(GO:0061439) glomerulus vasculature morphogenesis(GO:0072103) glomerular capillary formation(GO:0072104)
0.7 2.2 GO:0002940 tRNA N2-guanine methylation(GO:0002940)
0.7 2.2 GO:0010863 positive regulation of phospholipase C activity(GO:0010863) regulation of phospholipase C activity(GO:1900274)
0.7 2.8 GO:0032755 positive regulation of interleukin-6 production(GO:0032755) protein import into mitochondrial intermembrane space(GO:0045041)
0.7 2.7 GO:0038093 Fc receptor signaling pathway(GO:0038093)
0.7 2.7 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520) monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.6 1.9 GO:0009193 pyrimidine ribonucleoside diphosphate metabolic process(GO:0009193) UDP metabolic process(GO:0046048)
0.6 1.7 GO:0045601 regulation of endothelial cell differentiation(GO:0045601)
0.5 1.6 GO:0005997 xylulose metabolic process(GO:0005997)
0.5 1.5 GO:0071431 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.5 4.3 GO:0055129 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.5 3.2 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.4 1.7 GO:0034164 regulation of toll-like receptor 9 signaling pathway(GO:0034163) negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.4 2.9 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.4 1.2 GO:0071514 genetic imprinting(GO:0071514)
0.4 1.6 GO:0061668 mitochondrial ribosome assembly(GO:0061668)
0.4 0.8 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.4 3.2 GO:0051013 microtubule severing(GO:0051013)
0.4 2.0 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.4 2.0 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.4 1.1 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
0.4 1.5 GO:0070900 mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.4 1.9 GO:0043476 pigment accumulation(GO:0043476)
0.4 1.5 GO:0072314 glomerular visceral epithelial cell fate commitment(GO:0072149) glomerular epithelial cell fate commitment(GO:0072314)
0.3 1.4 GO:0042754 negative regulation of circadian rhythm(GO:0042754)
0.3 1.0 GO:0035676 anterior lateral line neuromast hair cell development(GO:0035676)
0.3 2.0 GO:0018160 peptidyl-pyrromethane cofactor linkage(GO:0018160)
0.3 1.0 GO:0070228 B cell apoptotic process(GO:0001783) regulation of B cell apoptotic process(GO:0002902) abscission(GO:0009838) mitotic cytokinesis checkpoint(GO:0044878) regulation of lymphocyte apoptotic process(GO:0070228)
0.3 1.3 GO:0006526 arginine biosynthetic process(GO:0006526)
0.3 1.3 GO:0070084 protein initiator methionine removal(GO:0070084)
0.3 0.9 GO:0045002 double-strand break repair via single-strand annealing(GO:0045002)
0.3 3.3 GO:0006622 protein targeting to lysosome(GO:0006622)
0.3 4.0 GO:1900077 negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.3 5.5 GO:0035196 production of miRNAs involved in gene silencing by miRNA(GO:0035196)
0.3 1.4 GO:0030219 megakaryocyte differentiation(GO:0030219)
0.3 1.4 GO:0097201 peptidyl-aspartic acid modification(GO:0018197) peptidyl-aspartic acid hydroxylation(GO:0042264) negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201)
0.3 1.7 GO:0006574 thymine catabolic process(GO:0006210) valine catabolic process(GO:0006574) thymine metabolic process(GO:0019859)
0.3 0.8 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371) positive regulation of endoplasmic reticulum tubular network organization(GO:1903373)
0.3 1.9 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.3 4.6 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.3 1.6 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.3 3.4 GO:0090309 methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.3 1.3 GO:0000050 urea cycle(GO:0000050) urea metabolic process(GO:0019627)
0.3 3.8 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.3 3.3 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.2 2.2 GO:0006465 signal peptide processing(GO:0006465)
0.2 0.7 GO:0032847 regulation of cellular pH reduction(GO:0032847) synaptic vesicle lumen acidification(GO:0097401) regulation of synaptic vesicle lumen acidification(GO:1901546)
0.2 1.7 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.2 3.4 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.2 1.7 GO:0070073 clustering of voltage-gated calcium channels(GO:0070073)
0.2 1.2 GO:0071939 vitamin A transport(GO:0071938) vitamin A import(GO:0071939)
0.2 0.9 GO:0003228 atrial cardiac muscle tissue development(GO:0003228)
0.2 2.2 GO:0045444 fat cell differentiation(GO:0045444)
0.2 0.7 GO:0006097 glyoxylate cycle(GO:0006097)
0.2 1.3 GO:0035989 tendon development(GO:0035989)
0.2 0.8 GO:0071871 response to monoamine(GO:0071867) response to catecholamine(GO:0071869) response to epinephrine(GO:0071871)
0.2 0.6 GO:1905048 regulation of metallopeptidase activity(GO:1905048)
0.2 0.6 GO:0048205 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.2 2.1 GO:0046850 regulation of bone remodeling(GO:0046850)
0.2 1.4 GO:0032185 septin ring organization(GO:0031106) septin cytoskeleton organization(GO:0032185)
0.2 2.0 GO:0072091 regulation of stem cell proliferation(GO:0072091)
0.2 1.2 GO:0030033 microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
0.2 0.8 GO:0010039 response to iron ion(GO:0010039)
0.2 9.6 GO:1904029 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.2 1.9 GO:0033700 phospholipid efflux(GO:0033700)
0.2 0.7 GO:0090386 phagosome maturation involved in apoptotic cell clearance(GO:0090386) phagolysosome assembly involved in apoptotic cell clearance(GO:0090387)
0.2 0.6 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.2 1.3 GO:0032366 intracellular sterol transport(GO:0032366)
0.2 0.7 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.2 2.5 GO:0045022 early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.2 3.0 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.2 2.6 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.2 0.7 GO:0006529 asparagine biosynthetic process(GO:0006529)
0.2 1.8 GO:0098719 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.2 2.0 GO:0003139 secondary heart field specification(GO:0003139) regulation of organ growth(GO:0046620)
0.2 1.0 GO:0086013 membrane repolarization during cardiac muscle cell action potential(GO:0086013)
0.2 0.8 GO:0007589 body fluid secretion(GO:0007589)
0.2 0.8 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.2 1.1 GO:0016266 O-glycan processing(GO:0016266)
0.2 1.2 GO:0044528 regulation of mitochondrial mRNA stability(GO:0044528)
0.2 1.7 GO:0046548 retinal rod cell development(GO:0046548)
0.1 0.6 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.1 1.1 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.1 1.1 GO:1901339 regulation of store-operated calcium channel activity(GO:1901339)
0.1 0.8 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.1 1.9 GO:0035493 SNARE complex assembly(GO:0035493)
0.1 1.5 GO:0035283 central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.1 0.7 GO:0035678 neuromast hair cell morphogenesis(GO:0035678)
0.1 0.9 GO:0006741 NADP biosynthetic process(GO:0006741)
0.1 0.9 GO:0045050 protein insertion into ER membrane by stop-transfer membrane-anchor sequence(GO:0045050)
0.1 1.3 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.1 3.2 GO:0051492 regulation of stress fiber assembly(GO:0051492)
0.1 2.6 GO:0043966 histone H3 acetylation(GO:0043966)
0.1 0.4 GO:0034421 post-translational protein acetylation(GO:0034421)
0.1 2.2 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.1 1.0 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.1 0.7 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.1 0.8 GO:0090243 fibroblast growth factor receptor signaling pathway involved in somitogenesis(GO:0090243)
0.1 2.7 GO:0070897 DNA-templated transcriptional preinitiation complex assembly(GO:0070897)
0.1 0.8 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.1 0.4 GO:0034086 maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.1 3.3 GO:0050821 protein stabilization(GO:0050821)
0.1 0.7 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.1 0.6 GO:1903573 negative regulation of response to endoplasmic reticulum stress(GO:1903573)
0.1 1.4 GO:0003382 epithelial cell morphogenesis(GO:0003382)
0.1 0.4 GO:0015722 canalicular bile acid transport(GO:0015722) bile acid secretion(GO:0032782)
0.1 2.7 GO:0030488 tRNA methylation(GO:0030488)
0.1 0.3 GO:0050847 progesterone receptor signaling pathway(GO:0050847)
0.1 2.6 GO:0042632 cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
0.1 2.3 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.1 0.3 GO:0001112 DNA-templated transcriptional open complex formation(GO:0001112) transcriptional open complex formation at RNA polymerase II promoter(GO:0001113) protein-DNA complex remodeling(GO:0001120)
0.1 1.2 GO:0032094 response to food(GO:0032094)
0.1 3.0 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 0.4 GO:0051645 Golgi localization(GO:0051645)
0.1 0.4 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.1 3.9 GO:0055088 lipid homeostasis(GO:0055088)
0.1 0.7 GO:0033292 T-tubule organization(GO:0033292)
0.1 2.1 GO:0006515 misfolded or incompletely synthesized protein catabolic process(GO:0006515)
0.1 1.2 GO:0042026 protein refolding(GO:0042026)
0.1 0.3 GO:0006266 DNA ligation(GO:0006266) DNA ligation involved in DNA repair(GO:0051103)
0.1 0.2 GO:0045830 regulation of isotype switching(GO:0045191) positive regulation of isotype switching(GO:0045830)
0.1 0.4 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.1 1.9 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.1 0.8 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.1 1.1 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.1 0.4 GO:0031649 heat generation(GO:0031649) regulation of heat generation(GO:0031650) positive regulation of heat generation(GO:0031652) regulation of phospholipid biosynthetic process(GO:0071071) negative regulation of phospholipid biosynthetic process(GO:0071072)
0.1 0.7 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.1 0.2 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971) positive regulation of cell cycle G2/M phase transition(GO:1902751)
0.1 2.7 GO:0006623 protein targeting to vacuole(GO:0006623)
0.1 0.7 GO:1902038 positive regulation of hematopoietic stem cell differentiation(GO:1902038)
0.1 3.4 GO:0051453 regulation of intracellular pH(GO:0051453)
0.1 1.1 GO:0035675 neuromast hair cell development(GO:0035675)
0.1 0.4 GO:0003222 ventricular trabecula myocardium morphogenesis(GO:0003222)
0.1 0.8 GO:0071479 cellular response to ionizing radiation(GO:0071479)
0.1 1.2 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.1 2.0 GO:1903039 positive regulation of homotypic cell-cell adhesion(GO:0034112) positive regulation of T cell activation(GO:0050870) positive regulation of leukocyte cell-cell adhesion(GO:1903039)
0.1 1.9 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.1 0.3 GO:0071962 mitotic sister chromatid cohesion, centromeric(GO:0071962)
0.1 0.4 GO:0097101 blood vessel endothelial cell fate specification(GO:0097101)
0.1 0.7 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.1 0.2 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.1 7.4 GO:0006261 DNA-dependent DNA replication(GO:0006261)
0.1 3.5 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.1 0.2 GO:0000066 mitochondrial ornithine transport(GO:0000066) mitochondrial L-ornithine transmembrane transport(GO:1990575)
0.1 4.4 GO:0071599 otic vesicle development(GO:0071599)
0.1 0.6 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.1 0.3 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.1 0.3 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.1 4.2 GO:0051170 nuclear import(GO:0051170)
0.1 3.5 GO:0034968 histone lysine methylation(GO:0034968)
0.1 0.5 GO:0035188 hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.1 1.4 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.1 2.9 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)
0.1 0.6 GO:0006382 adenosine to inosine editing(GO:0006382)
0.1 0.5 GO:0046501 protoporphyrinogen IX biosynthetic process(GO:0006782) protoporphyrinogen IX metabolic process(GO:0046501)
0.1 0.5 GO:0016119 carotene metabolic process(GO:0016119) carotene catabolic process(GO:0016121) terpene metabolic process(GO:0042214) terpene catabolic process(GO:0046247)
0.1 0.8 GO:0006265 DNA topological change(GO:0006265)
0.1 1.7 GO:0046890 regulation of lipid biosynthetic process(GO:0046890)
0.0 0.2 GO:0006535 cysteine biosynthetic process from serine(GO:0006535) hydrogen sulfide biosynthetic process(GO:0070814)
0.0 0.4 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.6 GO:1901970 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0 4.1 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 0.3 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 4.0 GO:0030837 negative regulation of actin filament polymerization(GO:0030837) negative regulation of protein polymerization(GO:0032272)
0.0 0.9 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 1.0 GO:0051307 meiotic chromosome separation(GO:0051307)
0.0 0.2 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.7 GO:0014823 response to activity(GO:0014823)
0.0 0.5 GO:0018216 peptidyl-arginine methylation(GO:0018216)
0.0 1.5 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 1.8 GO:0043534 blood vessel endothelial cell migration(GO:0043534)
0.0 0.1 GO:0006678 glucosylceramide metabolic process(GO:0006678)
0.0 0.6 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.2 GO:0070650 actin filament bundle distribution(GO:0070650)
0.0 0.2 GO:0016332 establishment or maintenance of polarity of embryonic epithelium(GO:0016332)
0.0 2.2 GO:0032869 cellular response to insulin stimulus(GO:0032869)
0.0 1.0 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.3 GO:0071459 protein localization to kinetochore(GO:0034501) protein localization to chromosome, centromeric region(GO:0071459)
0.0 0.2 GO:0006086 acetyl-CoA biosynthetic process from pyruvate(GO:0006086)
0.0 0.1 GO:0021611 facial nerve formation(GO:0021611)
0.0 1.9 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0 0.2 GO:0048730 epidermis morphogenesis(GO:0048730)
0.0 0.1 GO:1903430 negative regulation of cell maturation(GO:1903430)
0.0 0.3 GO:0021707 cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.5 GO:0031647 regulation of protein stability(GO:0031647)
0.0 0.3 GO:2000036 regulation of stem cell population maintenance(GO:2000036)
0.0 1.3 GO:0000281 mitotic cytokinesis(GO:0000281)
0.0 0.4 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.0 0.6 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.0 0.1 GO:0045724 positive regulation of cilium assembly(GO:0045724)
0.0 0.3 GO:0006567 threonine metabolic process(GO:0006566) threonine catabolic process(GO:0006567)
0.0 0.5 GO:0030259 lipid glycosylation(GO:0030259)
0.0 1.3 GO:0043297 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.0 0.6 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.0 0.1 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.0 0.6 GO:0006479 protein methylation(GO:0006479) protein alkylation(GO:0008213)
0.0 0.3 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.0 0.3 GO:0099638 neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887) endosome to plasma membrane protein transport(GO:0099638) neurotransmitter receptor transport, endosome to plasma membrane(GO:0099639)
0.0 0.3 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)
0.0 0.2 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 1.1 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.1 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 1.7 GO:0000070 mitotic sister chromatid segregation(GO:0000070)
0.0 0.6 GO:0008345 larval locomotory behavior(GO:0008345) larval behavior(GO:0030537)
0.0 0.4 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.0 2.3 GO:0008033 tRNA processing(GO:0008033)
0.0 0.3 GO:0006693 prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693)
0.0 0.6 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.3 GO:0014028 notochord formation(GO:0014028)
0.0 1.3 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 0.1 GO:0034080 chromatin remodeling at centromere(GO:0031055) CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 1.3 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 9.1 GO:0008380 RNA splicing(GO:0008380)
0.0 0.7 GO:0061035 regulation of cartilage development(GO:0061035)
0.0 0.5 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.0 GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.0 0.3 GO:0045116 protein neddylation(GO:0045116)
0.0 2.2 GO:0060027 convergent extension involved in gastrulation(GO:0060027)
0.0 0.6 GO:0016925 protein sumoylation(GO:0016925)
0.0 0.1 GO:0071501 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 0.3 GO:0042752 regulation of circadian rhythm(GO:0042752)
0.0 2.4 GO:0006417 regulation of translation(GO:0006417)
0.0 0.2 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.0 0.5 GO:0042129 regulation of T cell proliferation(GO:0042129)
0.0 0.8 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862) regulation of pathway-restricted SMAD protein phosphorylation(GO:0060393)
0.0 0.3 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.1 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.3 GO:0030817 regulation of cAMP metabolic process(GO:0030814) regulation of cAMP biosynthetic process(GO:0030817) regulation of adenylate cyclase activity(GO:0045761)
0.0 1.6 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 0.2 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 0.2 GO:0070527 platelet aggregation(GO:0070527)
0.0 0.9 GO:0071875 adrenergic receptor signaling pathway(GO:0071875)
0.0 0.7 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 0.1 GO:0046294 formaldehyde metabolic process(GO:0046292) formaldehyde catabolic process(GO:0046294)
0.0 0.1 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.5 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 1.0 GO:0031101 fin regeneration(GO:0031101)
0.0 0.1 GO:0015840 urea transport(GO:0015840)
0.0 0.7 GO:0051262 protein tetramerization(GO:0051262)
0.0 0.2 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.4 GO:0097205 renal filtration(GO:0097205)
0.0 0.4 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.2 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.8 GO:1990542 mitochondrial transmembrane transport(GO:1990542)
0.0 0.2 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.1 GO:0090075 relaxation of muscle(GO:0090075)
0.0 2.1 GO:0006397 mRNA processing(GO:0006397)
0.0 1.3 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.3 GO:0051209 release of sequestered calcium ion into cytosol(GO:0051209)
0.0 0.1 GO:0015886 heme transport(GO:0015886) iron coordination entity transport(GO:1901678)
0.0 0.0 GO:0030242 pexophagy(GO:0030242)
0.0 0.4 GO:0006368 transcription elongation from RNA polymerase II promoter(GO:0006368)
0.0 0.2 GO:0006198 cAMP catabolic process(GO:0006198)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 10.1 GO:0097134 cyclin E1-CDK2 complex(GO:0097134)
1.0 4.1 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.8 4.9 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.6 3.1 GO:0005899 insulin receptor complex(GO:0005899)
0.6 2.9 GO:0031415 NatA complex(GO:0031415)
0.5 1.5 GO:0034456 CURI complex(GO:0032545) UTP-C complex(GO:0034456)
0.5 1.4 GO:0000941 condensed nuclear chromosome inner kinetochore(GO:0000941)
0.4 3.5 GO:0000796 condensin complex(GO:0000796)
0.4 3.0 GO:0048500 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.4 1.7 GO:0005787 signal peptidase complex(GO:0005787)
0.4 2.5 GO:0070695 FHF complex(GO:0070695)
0.4 1.5 GO:0070319 Golgi to plasma membrane transport vesicle(GO:0070319)
0.3 2.2 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.3 2.1 GO:0070847 core mediator complex(GO:0070847)
0.3 3.2 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.3 0.8 GO:0098826 endoplasmic reticulum tubular network membrane(GO:0098826)
0.3 3.1 GO:0097431 mitotic spindle pole(GO:0097431)
0.3 1.3 GO:0034657 GID complex(GO:0034657)
0.3 8.9 GO:0043596 nuclear replication fork(GO:0043596)
0.3 2.0 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.2 1.4 GO:0071012 U2-type catalytic step 1 spliceosome(GO:0071006) catalytic step 1 spliceosome(GO:0071012)
0.2 1.7 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.2 6.6 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.2 1.4 GO:0005826 actomyosin contractile ring(GO:0005826)
0.2 1.2 GO:0000836 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.2 2.1 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.2 3.4 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.2 0.8 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.2 1.1 GO:0005955 calcineurin complex(GO:0005955)
0.2 0.7 GO:0043291 RAVE complex(GO:0043291)
0.2 0.5 GO:1990072 TRAPPIII protein complex(GO:1990072)
0.2 3.5 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.2 1.2 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.2 1.0 GO:0032133 chromosome passenger complex(GO:0032133)
0.2 0.6 GO:1990909 Wnt signalosome(GO:1990909)
0.2 3.6 GO:0005686 U2 snRNP(GO:0005686)
0.1 0.6 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.1 1.1 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 2.8 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 1.3 GO:0071782 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.1 3.2 GO:0035861 site of double-strand break(GO:0035861)
0.1 0.5 GO:0008290 F-actin capping protein complex(GO:0008290)
0.1 0.8 GO:0071256 translocon complex(GO:0071256)
0.1 0.7 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.1 0.6 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.1 0.7 GO:0035517 PR-DUB complex(GO:0035517)
0.1 0.8 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.1 0.5 GO:0030314 junctional membrane complex(GO:0030314)
0.1 0.3 GO:0000818 nuclear MIS12/MIND complex(GO:0000818)
0.1 1.4 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.1 0.5 GO:0031501 mannosyltransferase complex(GO:0031501)
0.1 0.9 GO:0032021 NELF complex(GO:0032021)
0.1 0.3 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.1 0.5 GO:0000938 GARP complex(GO:0000938)
0.1 1.2 GO:0002102 podosome(GO:0002102)
0.1 0.9 GO:0072546 ER membrane protein complex(GO:0072546)
0.1 0.5 GO:0030914 STAGA complex(GO:0030914)
0.1 1.3 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1 0.7 GO:0045335 phagocytic vesicle(GO:0045335)
0.1 7.7 GO:0016607 nuclear speck(GO:0016607)
0.1 0.9 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.1 0.6 GO:0031526 brush border membrane(GO:0031526)
0.1 1.6 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.1 0.3 GO:0005673 transcription factor TFIIE complex(GO:0005673)
0.1 0.7 GO:0030126 COPI vesicle coat(GO:0030126)
0.1 0.3 GO:0018444 translation release factor complex(GO:0018444)
0.1 0.3 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.1 1.4 GO:0031932 TORC2 complex(GO:0031932)
0.1 0.2 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.1 0.8 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 15.5 GO:0000323 lytic vacuole(GO:0000323)
0.1 0.7 GO:0016363 nuclear matrix(GO:0016363)
0.1 1.8 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.1 1.2 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.1 3.3 GO:0032432 actin filament bundle(GO:0032432)
0.0 0.2 GO:0035339 SPOTS complex(GO:0035339)
0.0 2.7 GO:0005643 nuclear pore(GO:0005643)
0.0 2.4 GO:0030496 midbody(GO:0030496)
0.0 3.2 GO:0055037 recycling endosome(GO:0055037)
0.0 0.1 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.3 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 1.8 GO:0031901 early endosome membrane(GO:0031901)
0.0 13.2 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 1.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.1 GO:0061673 mitotic spindle astral microtubule(GO:0061673)
0.0 0.5 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.3 GO:0043194 axon initial segment(GO:0043194)
0.0 0.2 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0 1.6 GO:0030139 endocytic vesicle(GO:0030139)
0.0 0.6 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.6 GO:0098844 dendritic spine head(GO:0044327) postsynaptic endocytic zone membrane(GO:0098844)
0.0 0.4 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 7.1 GO:0005912 adherens junction(GO:0005912)
0.0 3.6 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.3 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.6 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.0 1.4 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.8 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.2 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.4 GO:0001726 ruffle(GO:0001726)
0.0 1.1 GO:0016591 DNA-directed RNA polymerase II, holoenzyme(GO:0016591)
0.0 0.2 GO:0033061 DNA recombinase mediator complex(GO:0033061)
0.0 0.3 GO:0005922 connexon complex(GO:0005922)
0.0 0.6 GO:0005684 U2-type spliceosomal complex(GO:0005684)
0.0 0.9 GO:0005902 microvillus(GO:0005902)
0.0 0.6 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 1.0 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 1.4 GO:0005871 kinesin complex(GO:0005871)
0.0 1.2 GO:0044309 dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.0 0.3 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 1.4 GO:0005795 Golgi stack(GO:0005795)
0.0 0.7 GO:0016592 mediator complex(GO:0016592)
0.0 0.4 GO:0031941 filamentous actin(GO:0031941)
0.0 0.1 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.8 GO:0030018 Z disc(GO:0030018)
0.0 0.1 GO:0071011 precatalytic spliceosome(GO:0071011)
0.0 0.9 GO:0014069 postsynaptic density(GO:0014069)
0.0 1.1 GO:0005604 basement membrane(GO:0005604)
0.0 0.2 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.9 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.2 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 4.9 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
1.0 4.1 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.9 4.3 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.9 2.6 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
0.8 3.2 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.7 3.6 GO:0030620 U2 snRNA binding(GO:0030620)
0.6 3.1 GO:0043560 insulin-activated receptor activity(GO:0005009) insulin receptor substrate binding(GO:0043560)
0.6 2.4 GO:0016842 amidine-lyase activity(GO:0016842)
0.6 3.0 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.6 1.7 GO:0071077 coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.6 2.2 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.5 5.3 GO:0035198 miRNA binding(GO:0035198)
0.5 2.1 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.5 2.0 GO:0004092 carnitine O-acetyltransferase activity(GO:0004092)
0.5 1.4 GO:0071532 ankyrin repeat binding(GO:0071532)
0.5 1.8 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.5 1.8 GO:0033149 FFAT motif binding(GO:0033149)
0.4 1.3 GO:0004087 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087)
0.4 1.7 GO:0033745 L-methionine-(R)-S-oxide reductase activity(GO:0033745)
0.4 1.2 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.4 1.6 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.4 4.1 GO:0015385 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.4 3.4 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.4 1.9 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012) phosphatidylcholine-translocating ATPase activity(GO:0090554) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.4 1.5 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.3 1.0 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.3 1.7 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.3 2.0 GO:0004418 hydroxymethylbilane synthase activity(GO:0004418)
0.3 3.8 GO:0005158 insulin receptor binding(GO:0005158)
0.3 0.9 GO:0070336 flap-structured DNA binding(GO:0070336)
0.3 1.5 GO:0016429 tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.3 3.2 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.3 1.2 GO:0032296 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.3 0.8 GO:0009041 uridylate kinase activity(GO:0009041)
0.3 3.2 GO:0008199 ferric iron binding(GO:0008199)
0.3 3.8 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.3 0.8 GO:0003994 aconitate hydratase activity(GO:0003994)
0.2 1.7 GO:0035252 UDP-xylosyltransferase activity(GO:0035252)
0.2 3.4 GO:0043994 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.2 1.7 GO:0000995 transcription factor activity, core RNA polymerase III binding(GO:0000995)
0.2 2.1 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.2 0.9 GO:0030626 U12 snRNA binding(GO:0030626)
0.2 2.9 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.2 0.7 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.2 1.5 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.2 1.0 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.2 2.5 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.2 0.6 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.2 2.8 GO:0005504 fatty acid binding(GO:0005504)
0.2 1.1 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.2 0.6 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.2 2.4 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.2 3.1 GO:0070122 isopeptidase activity(GO:0070122)
0.2 1.7 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.2 1.2 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.2 1.2 GO:0034632 retinol transporter activity(GO:0034632)
0.2 0.7 GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
0.2 3.0 GO:0002039 p53 binding(GO:0002039)
0.2 1.1 GO:0017070 U6 snRNA binding(GO:0017070)
0.2 3.2 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.2 3.0 GO:0001671 ATPase activator activity(GO:0001671)
0.1 1.2 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.1 9.6 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 1.9 GO:0005537 mannose binding(GO:0005537)
0.1 4.4 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 1.1 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 1.0 GO:0035173 histone kinase activity(GO:0035173)
0.1 1.1 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.1 0.8 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.1 2.2 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 0.8 GO:0008142 oxysterol binding(GO:0008142)
0.1 0.8 GO:0022889 serine transmembrane transporter activity(GO:0022889)
0.1 2.7 GO:0048038 quinone binding(GO:0048038)
0.1 0.9 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 1.0 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.1 2.7 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 0.9 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1 2.6 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.1 2.4 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 0.4 GO:0015432 canalicular bile acid transmembrane transporter activity(GO:0015126) bile acid-exporting ATPase activity(GO:0015432)
0.1 0.3 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 0.9 GO:0032977 membrane insertase activity(GO:0032977)
0.1 2.3 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.1 0.4 GO:0046997 oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.1 0.3 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.1 3.9 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.1 0.5 GO:0048156 tau protein binding(GO:0048156)
0.1 0.5 GO:0004376 glycolipid mannosyltransferase activity(GO:0004376)
0.1 0.5 GO:0035613 RNA stem-loop binding(GO:0035613)
0.1 2.6 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1 0.8 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 1.2 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 2.1 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.1 1.5 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.1 2.6 GO:0051087 chaperone binding(GO:0051087)
0.1 0.5 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.1 0.3 GO:0004968 gonadotropin-releasing hormone receptor activity(GO:0004968)
0.1 0.8 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 0.8 GO:0004526 ribonuclease P activity(GO:0004526)
0.1 0.2 GO:0070051 fibrinogen binding(GO:0070051)
0.1 0.6 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.1 1.5 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 1.7 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor(GO:0016620)
0.1 0.8 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439) phosphatidylinositol phosphate 5-phosphatase activity(GO:0034595)
0.1 0.4 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1 0.2 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.1 0.3 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 0.6 GO:0005042 netrin receptor activity(GO:0005042)
0.1 1.0 GO:0016251 obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.1 0.2 GO:0008517 folic acid transporter activity(GO:0008517) FAD transmembrane transporter activity(GO:0015230)
0.1 0.3 GO:0015616 DNA translocase activity(GO:0015616)
0.1 0.3 GO:0008743 L-threonine 3-dehydrogenase activity(GO:0008743)
0.1 0.5 GO:0051920 peroxiredoxin activity(GO:0051920)
0.1 0.9 GO:0045134 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.1 0.6 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1 0.6 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.1 1.0 GO:0051371 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.1 0.5 GO:0010436 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.1 0.5 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.1 0.6 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.2 GO:0004122 cystathionine beta-synthase activity(GO:0004122)
0.0 0.6 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.7 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 2.9 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.2 GO:0034416 bisphosphoglycerate phosphatase activity(GO:0034416)
0.0 4.0 GO:0036459 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 1.2 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.9 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.0 0.3 GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.2 GO:0004739 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.5 GO:0031994 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
0.0 2.5 GO:0017124 SH3 domain binding(GO:0017124)
0.0 3.7 GO:0019904 protein domain specific binding(GO:0019904)
0.0 0.7 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 1.5 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.8 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 2.2 GO:0061650 ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.0 1.3 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 4.7 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor(GO:0016616)
0.0 1.5 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.6 GO:0031386 protein tag(GO:0031386)
0.0 3.0 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 1.0 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.8 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.2 GO:0070330 aromatase activity(GO:0070330)
0.0 3.2 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 2.0 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 5.4 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.0 0.2 GO:0030284 estrogen receptor activity(GO:0030284)
0.0 0.2 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0 0.9 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 0.1 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.0 0.6 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.0 0.8 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.8 GO:0019003 GDP binding(GO:0019003)
0.0 1.7 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.0 0.2 GO:0052796 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 0.5 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 1.2 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.1 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.0 0.3 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.1 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.0 0.6 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.2 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.7 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.1 GO:0050218 propionate-CoA ligase activity(GO:0050218)
0.0 0.1 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.3 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.1 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.1 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.1 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.0 GO:0000703 oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity(GO:0000703)
0.0 0.0 GO:0097643 amylin receptor activity(GO:0097643)
0.0 1.0 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.3 GO:0016836 hydro-lyase activity(GO:0016836)
0.0 3.8 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 4.6 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.1 GO:2001069 glycogen binding(GO:2001069)
0.0 2.3 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 1.2 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 6.1 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 1.4 GO:0003774 motor activity(GO:0003774)
0.0 0.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 1.3 GO:0042626 P-P-bond-hydrolysis-driven transmembrane transporter activity(GO:0015405) hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances(GO:0016820) ATPase activity, coupled to transmembrane movement of substances(GO:0042626) ATPase activity, coupled to movement of substances(GO:0043492)
0.0 0.2 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.6 GO:0008408 3'-5' exonuclease activity(GO:0008408)
0.0 0.3 GO:0017022 myosin binding(GO:0017022)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 9.6 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.2 3.9 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.2 7.0 PID AURORA B PATHWAY Aurora B signaling
0.2 3.7 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.2 3.7 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.1 0.7 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.1 2.8 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 2.0 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 3.3 PID ARF6 PATHWAY Arf6 signaling events
0.1 1.3 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.1 2.2 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.1 0.8 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 1.4 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1 2.6 ST GAQ PATHWAY G alpha q Pathway
0.1 3.2 PID NCADHERIN PATHWAY N-cadherin signaling events
0.1 0.3 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.1 0.6 PID CDC42 PATHWAY CDC42 signaling events
0.1 0.6 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1 2.5 PID FOXO PATHWAY FoxO family signaling
0.1 1.0 PID IL3 PATHWAY IL3-mediated signaling events
0.0 2.1 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 1.3 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.2 PID REELIN PATHWAY Reelin signaling pathway
0.0 1.2 PID ATM PATHWAY ATM pathway
0.0 0.9 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.3 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.7 PID BMP PATHWAY BMP receptor signaling
0.0 0.5 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.5 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.5 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 0.3 PID FGF PATHWAY FGF signaling pathway
0.0 0.5 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.5 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.1 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 9.6 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.3 6.2 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.2 2.1 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.2 1.7 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.2 2.5 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.2 1.7 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.2 3.2 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 2.1 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.1 2.6 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.1 1.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 2.0 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 1.4 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.1 1.7 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 1.5 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 0.8 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.1 2.5 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.1 0.9 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.1 0.9 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.1 3.5 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.1 1.5 REACTOME KINESINS Genes involved in Kinesins
0.1 3.0 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1 0.7 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 0.7 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 0.5 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 0.6 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 1.6 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.1 2.0 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 0.6 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 2.2 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.3 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.0 0.3 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 0.9 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.1 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 0.8 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.8 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 1.2 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.3 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 2.8 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 4.0 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 1.9 REACTOME SIGNALING BY SCF KIT Genes involved in Signaling by SCF-KIT
0.0 0.5 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 2.5 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 1.1 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.7 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.3 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.7 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 1.5 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.2 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.5 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.6 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.0 0.6 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 1.0 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.2 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.4 REACTOME MITOTIC G2 G2 M PHASES Genes involved in Mitotic G2-G2/M phases
0.0 2.5 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.1 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.7 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.1 REACTOME ADP SIGNALLING THROUGH P2RY1 Genes involved in ADP signalling through P2Y purinoceptor 1
0.0 1.1 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.1 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.1 REACTOME SIGNALING BY ERBB2 Genes involved in Signaling by ERBB2
0.0 0.2 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 0.2 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.1 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.1 REACTOME PURINE SALVAGE Genes involved in Purine salvage