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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for onecut1+onecutl

Z-value: 0.40

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Transcription factors associated with onecut1+onecutl

Gene Symbol Gene ID Gene Info
onecut1
ENSDARG00000007982 one cut homeobox 1
onecutl
ENSDARG00000040253 one cut domain, family member, like
onecut1
ENSDARG00000112251 one cut homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
onecut1dr11_v1_chr18_+_38755023_387550240.719.5e-04Click!
onecutldr11_v1_chr16_-_29528198_295281980.551.9e-02Click!

Activity profile of onecut1+onecutl motif

Sorted Z-values of onecut1+onecutl motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr23_-_31372639 0.87 ENSDART00000179908
ENSDART00000135620
ENSDART00000053367
hmgn3
high mobility group nucleosomal binding domain 3
chr15_-_19677511 0.85 ENSDART00000043743
si:dkey-4p15.3
si:dkey-4p15.3
chr3_-_49382896 0.81 ENSDART00000169115
si:ch73-167f10.1
si:ch73-167f10.1
chr17_-_10025234 0.80 ENSDART00000008355
cfl2
cofilin 2 (muscle)
chr24_+_12690163 0.70 ENSDART00000100644
rec8b
REC8 meiotic recombination protein b
chr20_+_23440632 0.69 ENSDART00000180685
ENSDART00000042820
si:dkey-90m5.4
si:dkey-90m5.4
chr22_+_16497670 0.61 ENSDART00000014330
ier5
immediate early response 5
chr13_+_37022601 0.60 ENSDART00000131800
ENSDART00000041300
esr2b
estrogen receptor 2b
chr22_+_81799 0.60 ENSDART00000163661
zgc:112334
zgc:112334
chr3_+_39853788 0.59 ENSDART00000154869
cacna1ha
calcium channel, voltage-dependent, T type, alpha 1H subunit a
chr1_-_52498146 0.56 ENSDART00000122217
acy3.2
aspartoacylase (aminocyclase) 3, tandem duplicate 2
chr4_+_77920666 0.55 ENSDART00000129523
ttll1
tubulin tyrosine ligase-like family, member 1
chr22_+_110158 0.54 ENSDART00000143698
prkar2ab
protein kinase, cAMP-dependent, regulatory, type II, alpha, B
chr3_+_60721342 0.50 ENSDART00000157772
foxj1a
forkhead box J1a
chr1_-_44704261 0.49 ENSDART00000133210
si:dkey-28b4.8
si:dkey-28b4.8
chr9_+_35876927 0.49 ENSDART00000138834
mab21l3
mab-21-like 3
chr3_-_39180048 0.48 ENSDART00000049720
cdk21
cyclin-dependent kinase 21
chr6_-_2627488 0.48 ENSDART00000044089
ENSDART00000158333
ENSDART00000155109
hyi
hydroxypyruvate isomerase
chr21_-_41305748 0.48 ENSDART00000170457
nsg2
neuronal vesicle trafficking associated 2
chr12_-_20373058 0.48 ENSDART00000066382
aqp8a.1
aquaporin 8a, tandem duplicate 1
chr5_+_25072894 0.47 ENSDART00000012268
mrpl41
mitochondrial ribosomal protein L41
chr6_-_40098641 0.46 ENSDART00000017402
ip6k2b
inositol hexakisphosphate kinase 2b
chr24_-_21674950 0.45 ENSDART00000123216
ENSDART00000046211
lnx2a
ligand of numb-protein X 2a
chr15_-_34056733 0.45 ENSDART00000170130
ENSDART00000188272
VWDE
si:dkey-30e9.7
chr22_-_15593824 0.43 ENSDART00000123125
tpm4a
tropomyosin 4a
chr25_+_5035343 0.42 ENSDART00000011751
parvb
parvin, beta
chr3_-_60711127 0.41 ENSDART00000184119
ubald2
UBA-like domain containing 2
chr7_+_72460911 0.41 ENSDART00000160682
ENSDART00000168532
HECTD4
HECT domain E3 ubiquitin protein ligase 4
chr1_-_44710937 0.40 ENSDART00000139036
si:dkey-28b4.7
si:dkey-28b4.7
chr16_+_23960744 0.40 ENSDART00000058965
apoeb
apolipoprotein Eb
chr25_+_34845115 0.40 ENSDART00000061996
tmem231
transmembrane protein 231
chr3_-_16250527 0.40 ENSDART00000146699
ENSDART00000141181
bckdhbl
branched chain keto acid dehydrogenase E1, beta polypeptide, like
chr5_-_13835461 0.39 ENSDART00000148297
ENSDART00000114841
add2
adducin 2 (beta)
chr25_-_3469576 0.39 ENSDART00000186738
hbp1
HMG-box transcription factor 1
chr13_+_24402406 0.39 ENSDART00000043002
rab1ab
RAB1A, member RAS oncogene family b
chr10_+_10210455 0.39 ENSDART00000144214
sh2d3ca
SH2 domain containing 3Ca
chr4_-_4507761 0.38 ENSDART00000130588
tbc1d30
TBC1 domain family, member 30
chr22_+_37888249 0.38 ENSDART00000076082
fetub
fetuin B
chr1_-_10071422 0.37 ENSDART00000135522
ENSDART00000033118
fga
fibrinogen alpha chain
chr17_-_20979077 0.37 ENSDART00000006676
phyhipla
phytanoyl-CoA 2-hydroxylase interacting protein-like a
chr2_-_16159491 0.36 ENSDART00000110059
vav3b
vav 3 guanine nucleotide exchange factor b
chr6_+_9191981 0.36 ENSDART00000150916
zgc:112392
zgc:112392
chr16_+_23960933 0.36 ENSDART00000146077
apoeb
apolipoprotein Eb
chr13_+_42406883 0.36 ENSDART00000084354
cpeb3
cytoplasmic polyadenylation element binding protein 3
chr16_+_19014886 0.35 ENSDART00000079298
si:ch211-254p10.2
si:ch211-254p10.2
chr6_+_33897624 0.35 ENSDART00000166706
ccdc17
coiled-coil domain containing 17
chr25_-_3979288 0.35 ENSDART00000157117
myrf
myelin regulatory factor
chr16_-_24518027 0.35 ENSDART00000134120
ENSDART00000143761
cadm4
cell adhesion molecule 4
chr14_-_2933185 0.35 ENSDART00000161677
ENSDART00000162446
ENSDART00000109378
si:dkey-201i24.6
si:dkey-201i24.6
chr20_+_25586099 0.35 ENSDART00000063122
ENSDART00000134047
cyp2p10
cytochrome P450, family 2, subfamily P, polypeptide 10
chr2_+_56463167 0.35 ENSDART00000123392
rab11bb
RAB11B, member RAS oncogene family, b
chr23_-_46034609 0.34 ENSDART00000158712
zgc:65873
zgc:65873
chr11_-_18705303 0.34 ENSDART00000059732
id1
inhibitor of DNA binding 1
chr25_+_4837915 0.33 ENSDART00000168016
gnb5a
guanine nucleotide binding protein (G protein), beta 5a
chr6_+_2097690 0.33 ENSDART00000193770
tgm2b
transglutaminase 2b
chr25_-_11088839 0.32 ENSDART00000154748
sv2bb
synaptic vesicle glycoprotein 2Bb
chr6_+_46431848 0.32 ENSDART00000181056
ENSDART00000144569
ENSDART00000064865
ENSDART00000133992
stau1
staufen double-stranded RNA binding protein 1
chr3_-_60602432 0.31 ENSDART00000163235
srsf2b
serine/arginine-rich splicing factor 2b
chr12_+_34378733 0.30 ENSDART00000018939
tha1
threonine aldolase 1
chr5_-_12093618 0.30 ENSDART00000161542
lrrc74b
leucine rich repeat containing 74B
chr22_-_10826 0.30 ENSDART00000125700
mrpl20
mitochondrial ribosomal protein L20
chr22_-_16494406 0.29 ENSDART00000062727
stx6
syntaxin 6
chr3_+_29640837 0.29 ENSDART00000132298
eif3d
eukaryotic translation initiation factor 3, subunit D
chr11_-_29657947 0.29 ENSDART00000125753
rpl22
ribosomal protein L22
chr3_-_37082618 0.29 ENSDART00000026701
ENSDART00000110716
tubg1
tubulin, gamma 1
chr17_-_28707898 0.28 ENSDART00000135752
ENSDART00000061853
ap4s1
adaptor-related protein complex 4, sigma 1 subunit
chr6_+_11438972 0.28 ENSDART00000029314
col5a2b
collagen, type V, alpha 2b
chr10_+_42358426 0.28 ENSDART00000025691
dbnla
drebrin-like a
chr24_-_26302375 0.28 ENSDART00000130696
cops9
COP9 signalosome subunit 9
chr1_-_52497834 0.28 ENSDART00000136469
ENSDART00000004233
acy3.2
aspartoacylase (aminocyclase) 3, tandem duplicate 2
chr7_-_22132265 0.27 ENSDART00000125284
ENSDART00000112978
nlgn2a
neuroligin 2a
chr3_-_23407720 0.27 ENSDART00000155658
rapgefl1
Rap guanine nucleotide exchange factor (GEF)-like 1
chr6_+_43015916 0.26 ENSDART00000064888
tcta
T cell leukemia translocation altered
chr2_+_38881165 0.26 ENSDART00000141850
carmil3
capping protein regulator and myosin 1 linker 3
chr7_+_41340520 0.25 ENSDART00000005127
garem
GRB2 associated, regulator of MAPK1
chr14_-_32893785 0.25 ENSDART00000169380
slc25a43
solute carrier family 25, member 43
chr19_+_9533008 0.25 ENSDART00000104607
fam131ba
family with sequence similarity 131, member Ba
chr6_+_55174744 0.25 ENSDART00000023562
SYT2
synaptotagmin 2
chr3_-_61205711 0.24 ENSDART00000055062
pvalb1
parvalbumin 1
chr16_+_10346277 0.24 ENSDART00000081092
si:dkeyp-77h1.4
si:dkeyp-77h1.4
chr20_+_33981946 0.24 ENSDART00000131775
si:dkey-51e6.1
si:dkey-51e6.1
chr5_+_55626693 0.23 ENSDART00000168908
ENSDART00000161412
ntrk2b
neurotrophic tyrosine kinase, receptor, type 2b
chr10_-_43771447 0.23 ENSDART00000052307
arrdc3b
arrestin domain containing 3b
chr10_+_35257651 0.23 ENSDART00000028940
styxl1
serine/threonine/tyrosine interacting-like 1
chr20_+_25563105 0.23 ENSDART00000063100
cyp2p6
cytochrome P450, family 2, subfamily P, polypeptide 6
chr3_+_59899452 0.23 ENSDART00000064311
arhgdia
Rho GDP dissociation inhibitor (GDI) alpha
chr7_+_38510197 0.23 ENSDART00000173468
ENSDART00000100479
slc7a9
solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
chr9_+_32073606 0.23 ENSDART00000184170
ENSDART00000180355
ENSDART00000110204
ENSDART00000123278
pikfyve
phosphoinositide kinase, FYVE finger containing
chr9_-_21067971 0.22 ENSDART00000004333
tbx15
T-box 15
chr10_-_34976812 0.22 ENSDART00000170625
smad9
SMAD family member 9
chr8_+_12925385 0.22 ENSDART00000085377
KIF2A
zgc:103670
chr21_+_17768174 0.22 ENSDART00000141380
rxraa
retinoid X receptor, alpha a
chr18_-_43866001 0.22 ENSDART00000150218
treh
trehalase (brush-border membrane glycoprotein)
chr11_+_7158723 0.22 ENSDART00000035560
tmem38a
transmembrane protein 38A
chr8_+_21437908 0.22 ENSDART00000142758
si:dkey-163f12.10
si:dkey-163f12.10
chr5_-_63515210 0.22 ENSDART00000022348
prdm12b
PR domain containing 12b
chr17_+_32500387 0.22 ENSDART00000018423
ywhaqb
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b
chr8_+_20863025 0.22 ENSDART00000015891
ENSDART00000187089
ENSDART00000146989
fzr1a
fizzy/cell division cycle 20 related 1a
chr2_+_21486529 0.21 ENSDART00000047468
inhbab
inhibin, beta Ab
chr21_+_9628854 0.21 ENSDART00000161753
ENSDART00000160711
mapk10
mitogen-activated protein kinase 10
chr9_+_32931625 0.21 ENSDART00000143484
cnga4
cyclic nucleotide gated channel alpha 4
chr19_-_9882821 0.21 ENSDART00000147128
cacng7a
calcium channel, voltage-dependent, gamma subunit 7a
chr7_+_12927944 0.21 ENSDART00000027329
fth1a
ferritin, heavy polypeptide 1a
chr1_+_30100257 0.21 ENSDART00000134311
vps8
vacuolar protein sorting 8 homolog (S. cerevisiae)
chr1_+_12767318 0.21 ENSDART00000162652
pcdh10a
protocadherin 10a
chr14_+_30568961 0.20 ENSDART00000184303
mrpl11
mitochondrial ribosomal protein L11
chr4_+_25558849 0.20 ENSDART00000113663
ENSDART00000100755
ENSDART00000111416
ENSDART00000127840
ENSDART00000168618
ENSDART00000111820
ENSDART00000113866
ENSDART00000110107
ENSDART00000111344
ENSDART00000108548
zgc:195175
zgc:195175
chr15_+_28202170 0.20 ENSDART00000077736
vtna
vitronectin a
chr2_+_32843133 0.20 ENSDART00000018501
opn4.1
opsin 4.1
chr8_-_40555340 0.20 ENSDART00000163348
NPC1L1
NPC1 like intracellular cholesterol transporter 1
chr2_-_23172708 0.19 ENSDART00000041365
prrx1a
paired related homeobox 1a
chr10_-_309894 0.19 ENSDART00000163287
CABZ01049607.1

chr15_+_14854666 0.19 ENSDART00000163066
diabloa
diablo, IAP-binding mitochondrial protein a
chr20_-_25626198 0.19 ENSDART00000126716
paics
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
chr19_+_27479563 0.19 ENSDART00000049368
ENSDART00000185426
atat1
alpha tubulin acetyltransferase 1
chr3_+_30500968 0.19 ENSDART00000103447
si:dkey-13n23.3
si:dkey-13n23.3
chr23_-_43486714 0.19 ENSDART00000169726
e2f1
E2F transcription factor 1
chr9_-_18424844 0.19 ENSDART00000154351
enox1
ecto-NOX disulfide-thiol exchanger 1
chr14_-_24081929 0.19 ENSDART00000158576
msx2a
muscle segment homeobox 2a
chr24_-_17444067 0.18 ENSDART00000155843
cntnap2a
contactin associated protein like 2a
chr22_-_10883394 0.18 ENSDART00000178051
ENSDART00000010991
arhgef18b
rho/rac guanine nucleotide exchange factor (GEF) 18b
chr20_-_23440955 0.18 ENSDART00000153386
slc10a4
solute carrier family 10, member 4
chr20_-_29051696 0.18 ENSDART00000140350
thbs1b
thrombospondin 1b
chr20_-_25626693 0.18 ENSDART00000132247
paics
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
chr10_-_14536399 0.18 ENSDART00000186501
hdhd2
haloacid dehalogenase-like hydrolase domain containing 2
chr14_-_25985698 0.18 ENSDART00000172909
ENSDART00000123053
atox1
antioxidant 1 copper chaperone
chr20_+_25626479 0.18 ENSDART00000143883
ppat
phosphoribosyl pyrophosphate amidotransferase
chr20_-_25626428 0.18 ENSDART00000136475
paics
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
chr4_-_9764767 0.18 ENSDART00000164328
ENSDART00000147699
mical3b
microtubule associated monooxygenase, calponin and LIM domain containing 3b
chr9_-_54716363 0.17 ENSDART00000162158
ENSDART00000168430
trappc2
trafficking protein particle complex 2
chr23_+_24598910 0.17 ENSDART00000126510
ENSDART00000078796
kansl2
KAT8 regulatory NSL complex subunit 2
chr24_-_39858710 0.17 ENSDART00000134251
slc12a7b
solute carrier family 12 (potassium/chloride transporter), member 7b
chr25_-_32311048 0.17 ENSDART00000181806
ENSDART00000086334
CU372926.1

chr19_+_27479838 0.17 ENSDART00000103922
atat1
alpha tubulin acetyltransferase 1
chr13_+_33689740 0.17 ENSDART00000161904
ephx5
epoxide hydrolase 5
chr13_+_35746440 0.17 ENSDART00000187859
gpr75
G protein-coupled receptor 75
chr19_+_5674907 0.17 ENSDART00000042189
pdk2b
pyruvate dehydrogenase kinase, isozyme 2b
chr2_-_51794472 0.16 ENSDART00000186652
BX908782.3

chr18_-_43866526 0.16 ENSDART00000111309
treh
trehalase (brush-border membrane glycoprotein)
chr5_-_29750377 0.16 ENSDART00000051474
barhl1a
BarH-like homeobox 1a
chr10_+_23099890 0.16 ENSDART00000135890
LTN1
si:dkey-175g6.5
chr1_+_40140498 0.16 ENSDART00000101640
zgc:152658
zgc:152658
chr17_+_8754426 0.16 ENSDART00000185519
edrf1
erythroid differentiation regulatory factor 1
chr2_+_35240485 0.16 ENSDART00000179804
tnr
tenascin R (restrictin, janusin)
chr8_-_19280856 0.16 ENSDART00000100473
zgc:77486
zgc:77486
chr21_-_45086170 0.16 ENSDART00000188963
rapgef6
Rap guanine nucleotide exchange factor (GEF) 6
chr21_-_35853245 0.16 ENSDART00000172245
sgcd
sarcoglycan, delta (dystrophin-associated glycoprotein)
chr6_-_43882696 0.15 ENSDART00000064938
foxp1b
forkhead box P1b
chr3_-_23406964 0.15 ENSDART00000114723
rapgefl1
Rap guanine nucleotide exchange factor (GEF)-like 1
chr9_-_21067673 0.15 ENSDART00000180257
tbx15
T-box 15
chr24_-_39826865 0.15 ENSDART00000089232
slc12a7b
solute carrier family 12 (potassium/chloride transporter), member 7b
chr2_+_35240764 0.15 ENSDART00000015827
tnr
tenascin R (restrictin, janusin)
chr20_+_25625872 0.15 ENSDART00000078385
ppat
phosphoribosyl pyrophosphate amidotransferase
chr13_+_28417297 0.15 ENSDART00000043658
slc2a15a
solute carrier family 2 (facilitated glucose transporter), member 15a
chr16_+_5184402 0.15 ENSDART00000156685
soga3a
SOGA family member 3a
chr6_+_52263236 0.14 ENSDART00000144174
esyt1b
extended synaptotagmin-like protein 1b
chr13_-_33000649 0.14 ENSDART00000133677
rbm25a
RNA binding motif protein 25a
chr3_-_28665291 0.14 ENSDART00000151670
fbxl16
F-box and leucine-rich repeat protein 16
chr11_+_6819050 0.14 ENSDART00000104289
rab3ab
RAB3A, member RAS oncogene family, b
chr15_-_14375452 0.14 ENSDART00000160675
ENSDART00000164028
ENSDART00000171642
dpf1
D4, zinc and double PHD fingers family 1
chr19_-_18626515 0.14 ENSDART00000160624
rps18
ribosomal protein S18
chr5_+_7393346 0.14 ENSDART00000164238
si:ch73-72b7.1
si:ch73-72b7.1
chr24_+_38223618 0.14 ENSDART00000003495
igl3v2
immunoglobulin light 3 variable 2
chr23_-_44494401 0.13 ENSDART00000114640
ENSDART00000148532
actl6b
actin-like 6B
chr20_-_52199296 0.13 ENSDART00000131806
ENSDART00000143668
hlx1
H2.0-like homeo box 1 (Drosophila)
chr19_-_3874986 0.13 ENSDART00000161830
thrap3b
thyroid hormone receptor associated protein 3b
chr19_-_21766461 0.13 ENSDART00000104279
znf516
zinc finger protein 516
chr25_+_31264155 0.13 ENSDART00000012256
tnni2a.3
troponin I type 2a (skeletal, fast), tandem duplicate 3
chr20_-_39273987 0.13 ENSDART00000127173
clu
clusterin
chr18_+_48576527 0.13 ENSDART00000167555
kcnj5
potassium inwardly-rectifying channel, subfamily J, member 5
chr18_-_26894732 0.13 ENSDART00000147735
ENSDART00000188938
BX470164.1
si:dkey-24l11.2

si:dkey-24l11.2
chr12_-_24060358 0.13 ENSDART00000050831
chac2
ChaC, cation transport regulator homolog 2 (E. coli)
chr20_-_39273505 0.13 ENSDART00000153114
clu
clusterin
chr15_-_23442891 0.13 ENSDART00000059376
ube4a
ubiquitination factor E4A (UFD2 homolog, yeast)
chr24_+_23730061 0.12 ENSDART00000080343
ppp1r42
protein phosphatase 1, regulatory subunit 42
chr17_+_53435279 0.12 ENSDART00000126630
cx52.9
connexin 52.9
chr1_+_55662491 0.12 ENSDART00000152386
adgre8
adhesion G protein-coupled receptor E8
chr20_+_12830448 0.12 ENSDART00000164754
BX547930.4

chr15_-_17213723 0.12 ENSDART00000156892
itgae.1
integrin, alpha E, tandem duplicate 1
chr14_-_28463835 0.11 ENSDART00000146344
ENSDART00000144076
nxt2
nuclear transport factor 2-like export factor 2
chr23_+_28648864 0.11 ENSDART00000189096
l1cama
L1 cell adhesion molecule, paralog a
chr4_+_20318127 0.11 ENSDART00000028856
ENSDART00000132909
cacna1c
calcium channel, voltage-dependent, L type, alpha 1C subunit
chr20_+_10723292 0.11 ENSDART00000152805
si:ch211-182e10.4
si:ch211-182e10.4
chr3_-_39648021 0.11 ENSDART00000055171
grapa
GRB2-related adaptor protein a
chr12_-_4781801 0.11 ENSDART00000167490
ENSDART00000121718
mapta
microtubule-associated protein tau a
chr4_+_7391110 0.11 ENSDART00000160708
ENSDART00000187823
tnni4a
troponin I4a
chr10_+_1638876 0.11 ENSDART00000184484
ENSDART00000060946
ENSDART00000181251
sgsm1b
small G protein signaling modulator 1b
chr21_+_9576176 0.11 ENSDART00000161289
ENSDART00000159899
ENSDART00000162834
mapk10
mitogen-activated protein kinase 10
chr10_-_23099809 0.11 ENSDART00000148333
ENSDART00000079703
ENSDART00000162444
nle1
notchless homolog 1 (Drosophila)
chr7_-_52842007 0.10 ENSDART00000182710
map1aa
microtubule-associated protein 1Aa
chr8_+_18101608 0.10 ENSDART00000140941
glis1b
GLIS family zinc finger 1b
chr6_+_3828560 0.10 ENSDART00000185273
ENSDART00000179091
gad1b
glutamate decarboxylase 1b
chr25_+_4760489 0.10 ENSDART00000167399
FP245455.1

chr7_-_20453661 0.10 ENSDART00000174001
ntn5
netrin 5
chr8_-_16259063 0.10 ENSDART00000057590
dmrta2
DMRT-like family A2
chr24_-_1356668 0.10 ENSDART00000188935
nrp1a
neuropilin 1a
chr10_+_23099365 0.10 ENSDART00000022170
LTN1
si:dkey-175g6.5
chr5_+_36693859 0.09 ENSDART00000019259
dlb
deltaB
chr12_+_4900981 0.09 ENSDART00000171507
cd79b
CD79b molecule, immunoglobulin-associated beta
chr17_+_25677458 0.09 ENSDART00000029703
kcnh1a
potassium voltage-gated channel, subfamily H (eag-related), member 1a

Network of associatons between targets according to the STRING database.

First level regulatory network of onecut1+onecutl

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0061178 insulin secretion involved in cellular response to glucose stimulus(GO:0035773) regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.3 0.8 GO:0030043 actin filament fragmentation(GO:0030043)
0.3 0.8 GO:0071830 chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830) intermediate-density lipoprotein particle clearance(GO:0071831)
0.1 0.4 GO:0005991 trehalose metabolic process(GO:0005991)
0.1 0.5 GO:1902019 regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.1 0.3 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.1 0.3 GO:0000212 meiotic spindle organization(GO:0000212)
0.1 0.3 GO:2000434 regulation of protein neddylation(GO:2000434)
0.1 0.9 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.1 0.2 GO:0035971 peptidyl-histidine dephosphorylation(GO:0035971)
0.1 0.2 GO:1990416 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551) cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.1 0.2 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.1 0.7 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.1 0.5 GO:0046487 glyoxylate metabolic process(GO:0046487)
0.1 0.2 GO:0016056 rhodopsin mediated signaling pathway(GO:0016056)
0.1 0.6 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.1 0.3 GO:0006545 glycine biosynthetic process(GO:0006545)
0.1 0.4 GO:0003232 bulbus arteriosus development(GO:0003232)
0.1 0.2 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.1 0.3 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.0 0.1 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.0 0.4 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.0 0.4 GO:0043217 myelin maintenance(GO:0043217)
0.0 0.2 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0 0.2 GO:0007624 ultradian rhythm(GO:0007624)
0.0 0.2 GO:0099612 protein localization to juxtaparanode region of axon(GO:0071205) protein localization to axon(GO:0099612)
0.0 0.2 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.0 0.6 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.0 0.1 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.0 0.5 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.5 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.2 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 0.4 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.5 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.0 0.4 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.0 0.2 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.3 GO:0097090 presynaptic membrane organization(GO:0097090) postsynaptic membrane assembly(GO:0097104) presynaptic membrane assembly(GO:0097105)
0.0 0.1 GO:0014896 muscle hypertrophy(GO:0014896)
0.0 0.2 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.0 0.1 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.2 GO:0086002 cardiac muscle cell action potential involved in contraction(GO:0086002)
0.0 0.1 GO:0060055 larval development(GO:0002164) larval heart development(GO:0007508) angiogenesis involved in wound healing(GO:0060055)
0.0 0.3 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.4 GO:0000731 DNA synthesis involved in DNA repair(GO:0000731)
0.0 0.4 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.0 0.8 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.0 0.4 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.4 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.1 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.3 GO:0071594 T cell differentiation in thymus(GO:0033077) thymocyte aggregation(GO:0071594)
0.0 0.1 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.2 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.0 0.3 GO:0098943 neurotransmitter receptor transport, postsynaptic endosome to lysosome(GO:0098943)
0.0 0.4 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 0.2 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.2 GO:0097324 melanocyte migration(GO:0097324)
0.0 0.1 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.0 GO:0055107 Golgi to secretory granule transport(GO:0055107)
0.0 0.6 GO:0042737 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.0 0.3 GO:0030316 osteoclast differentiation(GO:0030316)
0.0 0.1 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.0 0.3 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 0.1 GO:0006751 glutathione catabolic process(GO:0006751)
0.0 0.5 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.0 GO:0042730 fibrinolysis(GO:0042730)
0.0 0.1 GO:0017006 protein-heme linkage(GO:0017003) protein-tetrapyrrole linkage(GO:0017006) cytochrome c-heme linkage(GO:0018063)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.1 0.4 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.7 GO:0030892 nuclear cohesin complex(GO:0000798) mitotic cohesin complex(GO:0030892) nuclear mitotic cohesin complex(GO:0034990) nuclear meiotic cohesin complex(GO:0034991)
0.1 0.3 GO:0060077 inhibitory synapse(GO:0060077)
0.1 0.4 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.1 0.3 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.5 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.7 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.1 GO:1990071 TRAPPII protein complex(GO:1990071)
0.0 0.3 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.3 GO:0042583 chromaffin granule(GO:0042583)
0.0 0.3 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.4 GO:0036038 MKS complex(GO:0036038)
0.0 0.3 GO:0002102 podosome(GO:0002102)
0.0 0.6 GO:0001518 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 0.4 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.1 GO:0019815 B cell receptor complex(GO:0019815)
0.0 0.2 GO:0033010 paranodal junction(GO:0033010)
0.0 0.2 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.3 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.7 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.2 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.3 GO:0016282 eukaryotic 43S preinitiation complex(GO:0016282)
0.0 0.1 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.1 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.0 0.6 GO:0016592 mediator complex(GO:0016592)
0.0 0.1 GO:0038037 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor heterodimeric complex(GO:0038039) G-protein coupled receptor complex(GO:0097648)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.2 0.6 GO:0005093 Rab GDP-dissociation inhibitor activity(GO:0005093)
0.1 0.5 GO:0004639 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity(GO:0004639)
0.1 0.4 GO:0015927 alpha,alpha-trehalase activity(GO:0004555) trehalase activity(GO:0015927)
0.1 0.6 GO:1903924 estradiol binding(GO:1903924)
0.1 0.3 GO:0098808 mRNA cap binding(GO:0098808)
0.1 0.6 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.1 0.5 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.1 0.2 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403) brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.1 0.8 GO:0004046 aminoacylase activity(GO:0004046)
0.1 0.2 GO:1990226 histone methyltransferase binding(GO:1990226)
0.1 0.2 GO:0101006 protein histidine phosphatase activity(GO:0101006)
0.1 0.2 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 0.2 GO:0033961 cis-stilbene-oxide hydrolase activity(GO:0033961)
0.1 0.5 GO:0015250 water channel activity(GO:0015250)
0.0 0.2 GO:1990757 anaphase-promoting complex binding(GO:0010997) ubiquitin ligase activator activity(GO:1990757)
0.0 0.4 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.0 0.9 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.5 GO:0070740 protein-glutamic acid ligase activity(GO:0070739) tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.2 GO:0016531 copper chaperone activity(GO:0016531)
0.0 0.5 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.5 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.5 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.1 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.0 0.2 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.0 0.3 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.1 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.0 0.2 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.2 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.5 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.5 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828)
0.0 0.1 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.2 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.4 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.1 GO:0008459 chondroitin 6-sulfotransferase activity(GO:0008459)
0.0 0.3 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.0 0.4 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.2 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.2 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.1 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.4 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.2 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.3 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.0 0.3 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.2 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.0 GO:0031835 neurokinin receptor binding(GO:0031834) substance P receptor binding(GO:0031835)
0.0 0.1 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.1 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.3 GO:0015377 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.0 0.3 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.1 GO:0004408 holocytochrome-c synthase activity(GO:0004408)
0.0 0.6 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.6 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.4 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.3 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.2 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.4 PID MYC PATHWAY C-MYC pathway
0.0 0.4 PID ILK PATHWAY Integrin-linked kinase signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.1 0.9 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.3 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.4 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.5 REACTOME BOTULINUM NEUROTOXICITY Genes involved in Botulinum neurotoxicity
0.0 0.4 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.3 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.2 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.2 REACTOME KINESINS Genes involved in Kinesins
0.0 0.2 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions