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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for onecut2

Z-value: 0.72

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Transcription factors associated with onecut2

Gene Symbol Gene ID Gene Info
onecut2
ENSDARG00000090387 one cut homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
onecut2dr11_v1_chr21_-_1742159_17421590.097.4e-01Click!

Activity profile of onecut2 motif

Sorted Z-values of onecut2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr8_-_32385989 2.65 ENSDART00000143716
ENSDART00000098850
lipg
lipase, endothelial
chr7_+_33372680 2.11 ENSDART00000193436
ENSDART00000099988
glceb
glucuronic acid epimerase b
chr19_-_41991104 1.62 ENSDART00000087055
trioa
trio Rho guanine nucleotide exchange factor a
chr18_+_20560616 1.58 ENSDART00000136710
ENSDART00000151974
ENSDART00000121699
ENSDART00000040074
wee2
WEE1 homolog 2 (S. pombe)
chr6_+_13232934 1.55 ENSDART00000089725
ino80db
INO80 complex subunit Db
chr4_-_4261673 1.54 ENSDART00000150694
cd9b
CD9 molecule b
chr15_-_31265375 1.46 ENSDART00000086592
vezf1b
vascular endothelial zinc finger 1b
chr21_-_37027252 1.44 ENSDART00000076483
zgc:77151
zgc:77151
chr5_-_23675222 1.43 ENSDART00000135153
TBC1D8B
si:dkey-110k5.6
chr12_-_4475890 1.25 ENSDART00000092492
si:ch211-173d10.1
si:ch211-173d10.1
chr19_+_42886413 1.19 ENSDART00000151298
arpp21
cAMP-regulated phosphoprotein, 21
chr2_-_39086540 1.16 ENSDART00000110826
NMNAT3
si:ch73-170l17.1
chr1_+_45958904 1.16 ENSDART00000108528
arhgef7b
Rho guanine nucleotide exchange factor (GEF) 7b
chr14_+_21699129 1.14 ENSDART00000073707
stx3a
syntaxin 3A
chr19_-_47570672 1.13 ENSDART00000112155
rrm2
ribonucleotide reductase M2 polypeptide
chr5_+_34549845 1.13 ENSDART00000139317
aif1l
allograft inflammatory factor 1-like
chr5_+_37406358 1.10 ENSDART00000162811
klhl13
kelch-like family member 13
chr2_+_19195841 1.09 ENSDART00000163137
ENSDART00000161095
elovl1a
ELOVL fatty acid elongase 1a
chr5_+_27267186 1.08 ENSDART00000182238
ENSDART00000087857
unc5db
unc-5 netrin receptor Db
chr6_+_4255319 1.07 ENSDART00000170351
nbeal1
neurobeachin-like 1
chr21_+_4116437 1.05 ENSDART00000167791
ENSDART00000123759
rapgef1b
Rap guanine nucleotide exchange factor (GEF) 1b
chr8_-_2616326 1.05 ENSDART00000027214
slc25a25a
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25a
chr2_+_42871831 1.04 ENSDART00000171393
efr3a
EFR3 homolog A (S. cerevisiae)
chr13_+_46941930 1.01 ENSDART00000056962
fbxo5
F-box protein 5
chr19_+_26072624 1.00 ENSDART00000147627
jarid2b
jumonji, AT rich interactive domain 2b
chr25_-_9805269 0.97 ENSDART00000192048
lrrc4c
leucine rich repeat containing 4C
chr5_+_36666715 0.95 ENSDART00000097686
zgc:153990
zgc:153990
chr14_+_21699414 0.95 ENSDART00000169942
stx3a
syntaxin 3A
chr5_+_34549365 0.93 ENSDART00000009500
aif1l
allograft inflammatory factor 1-like
chr6_+_38880166 0.93 ENSDART00000019939
ENSDART00000144286
bin2b
bridging integrator 2b
chr21_-_17037907 0.90 ENSDART00000101263
ube2g1b
ubiquitin-conjugating enzyme E2G 1b (UBC7 homolog, yeast)
chr3_+_36646054 0.90 ENSDART00000170013
ENSDART00000159948
gspt1l
G1 to S phase transition 1, like
chr8_+_21280360 0.89 ENSDART00000144488
itpr3
inositol 1,4,5-trisphosphate receptor, type 3
chr17_+_6538733 0.87 ENSDART00000193712
slc5a6b
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
chr13_-_35908275 0.87 ENSDART00000013961
mycla
MYCL proto-oncogene, bHLH transcription factor a
chr9_-_7287128 0.87 ENSDART00000176281
ENSDART00000065803
mitd1
MIT, microtubule interacting and transport, domain containing 1
chr5_+_25762271 0.87 ENSDART00000181323
tmem2
transmembrane protein 2
chr9_-_7287375 0.86 ENSDART00000128352
mitd1
MIT, microtubule interacting and transport, domain containing 1
chr23_+_19655301 0.80 ENSDART00000104441
ENSDART00000135269
abhd6b
abhydrolase domain containing 6b
chr5_+_58455488 0.79 ENSDART00000038602
ENSDART00000127958
slc37a2
solute carrier family 37 (glucose-6-phosphate transporter), member 2
chr15_-_30984557 0.79 ENSDART00000080328
nf1a
neurofibromin 1a
chr9_-_14143370 0.75 ENSDART00000108950
ttll4
tubulin tyrosine ligase-like family, member 4
chr17_-_43623356 0.70 ENSDART00000075596
ENSDART00000136431
rtkn2a
rhotekin 2a
chr3_+_28581397 0.70 ENSDART00000150893
sept12
septin 12
chr4_+_26628822 0.69 ENSDART00000191030
ENSDART00000186113
ENSDART00000186764
ENSDART00000165158
iqsec3a
IQ motif and Sec7 domain 3a
chr18_-_25051846 0.69 ENSDART00000013082
st8sia2
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
chr12_-_25217217 0.69 ENSDART00000152931
kcng3
potassium voltage-gated channel, subfamily G, member 3
chr21_+_22878834 0.68 ENSDART00000065562
pcf11
PCF11 cleavage and polyadenylation factor subunit
chr13_-_31008275 0.67 ENSDART00000139394
wdfy4
WDFY family member 4
chr15_+_24005289 0.67 ENSDART00000088648
myo18ab
myosin XVIIIAb
chr13_-_21650404 0.65 ENSDART00000078352
tspan14
tetraspanin 14
chr20_-_6196989 0.65 ENSDART00000013343
b4galt6
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6
chr9_-_30258957 0.63 ENSDART00000144259
si:dkey-100n23.5
si:dkey-100n23.5
chr16_+_5612547 0.63 ENSDART00000140226
ENSDART00000189352
CYTH2
si:dkey-283b15.4
chr10_-_33156789 0.61 ENSDART00000192268
ENSDART00000182065
ENSDART00000081170
cux1a
cut-like homeobox 1a
chr4_-_14531687 0.60 ENSDART00000182093
ENSDART00000159447
plxnb2a
plexin b2a
chr5_+_61301525 0.55 ENSDART00000128773
doc2b
double C2-like domains, beta
chr15_-_23721618 0.55 ENSDART00000109318
zc3h4
zinc finger CCCH-type containing 4
chr21_+_3901775 0.54 ENSDART00000053609
dolpp1
dolichyldiphosphatase 1
chr23_+_32101202 0.54 ENSDART00000000992
zgc:56699
zgc:56699
chr19_+_41006975 0.53 ENSDART00000138555
ENSDART00000049842
casd1
CAS1 domain containing 1
chr6_-_16456093 0.51 ENSDART00000083305
ENSDART00000181640
slc19a2
solute carrier family 19 (thiamine transporter), member 2
chr5_-_69212184 0.51 ENSDART00000053963
mat2ab
methionine adenosyltransferase II, alpha b
chr25_+_32496877 0.50 ENSDART00000132698
ctdspl2a
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2a
chr1_-_23157583 0.49 ENSDART00000144208
adgrl3.1
adhesion G protein-coupled receptor L3.1
chr7_+_42206847 0.48 ENSDART00000149250
phkb
phosphorylase kinase, beta
chr7_-_7797654 0.48 ENSDART00000084503
ENSDART00000192779
ENSDART00000173079
trmt10b
tRNA methyltransferase 10B
chr8_-_621142 0.47 ENSDART00000187576
ENSDART00000190316
si:ch211-87m7.2
si:ch211-87m7.2
chr25_-_21085661 0.47 ENSDART00000099355
prr5a
proline rich 5a (renal)
chr7_+_30933867 0.47 ENSDART00000156325
tjp1a
tight junction protein 1a
chr8_-_11067079 0.46 ENSDART00000181986
dennd2c
DENN/MADD domain containing 2C
chr18_+_50890749 0.44 ENSDART00000174109
si:ch1073-450f2.1
si:ch1073-450f2.1
chr18_+_15644559 0.44 ENSDART00000061794
nr1h4
nuclear receptor subfamily 1, group H, member 4
chr19_-_7525588 0.43 ENSDART00000092256
mrpl9
mitochondrial ribosomal protein L9
chr1_-_28861226 0.43 ENSDART00000075502
timmdc1
translocase of inner mitochondrial membrane domain containing 1
chr7_-_49651378 0.42 ENSDART00000015040
hrasb
-Ha-ras Harvey rat sarcoma viral oncogene homolog b
chr5_+_61361815 0.42 ENSDART00000009507
gatsl2
GATS protein-like 2
chr2_+_45300512 0.42 ENSDART00000144704
camsap2b
calmodulin regulated spectrin-associated protein family, member 2b
chr18_+_50276337 0.40 ENSDART00000140352
si:dkey-105e17.1
si:dkey-105e17.1
chr7_+_38265363 0.39 ENSDART00000009386
gpatch1
G patch domain containing 1
chr18_-_44847855 0.38 ENSDART00000086823
srpr
signal recognition particle receptor (docking protein)
chr19_-_17526735 0.38 ENSDART00000189391
thrb
thyroid hormone receptor beta
chr2_-_32387441 0.37 ENSDART00000148202
ubtfl
upstream binding transcription factor, like
chr21_+_17005737 0.36 ENSDART00000101246
vps29
vacuolar protein sorting 29 homolog (S. cerevisiae)
chr3_-_6441619 0.35 ENSDART00000157771
ENSDART00000166758
sumo2b
small ubiquitin-like modifier 2b
chr23_-_20002459 0.34 ENSDART00000163396
b4galt3
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3
chr5_-_65158203 0.33 ENSDART00000171656
sh2d3cb
SH2 domain containing 3Cb
chr22_+_18319666 0.33 ENSDART00000033103
gatad2ab
GATA zinc finger domain containing 2Ab
chr5_-_29643930 0.33 ENSDART00000161250
grin1b
glutamate receptor, ionotropic, N-methyl D-aspartate 1b
chr4_-_13255700 0.31 ENSDART00000162277
ENSDART00000026593
grip1
glutamate receptor interacting protein 1
chr18_+_8937718 0.31 ENSDART00000138115
si:dkey-5i3.1
si:dkey-5i3.1
chr22_-_38360205 0.31 ENSDART00000162055
mark1
MAP/microtubule affinity-regulating kinase 1
chr22_+_18156000 0.31 ENSDART00000143483
ENSDART00000136133
nr2c2ap
nuclear receptor 2C2-associated protein
chr18_-_37007294 0.30 ENSDART00000088309
map3k10
mitogen-activated protein kinase kinase kinase 10
chr3_-_8399774 0.29 ENSDART00000190238
ENSDART00000113140
ENSDART00000132949
rbfox3b
RNA binding fox-1 homolog 3b
chr8_+_40477264 0.28 ENSDART00000085559
gck
glucokinase (hexokinase 4)
chr2_+_7818368 0.28 ENSDART00000007068
kcnmb2
potassium large conductance calcium-activated channel, subfamily M, beta member 2
chr25_+_27410352 0.28 ENSDART00000154362
pot1
protection of telomeres 1 homolog
chr14_+_35024521 0.26 ENSDART00000158634
ENSDART00000170631
ebf3a
early B cell factor 3a
chr14_-_41243180 0.26 ENSDART00000184548
drp2
dystrophin related protein 2
chr23_-_3721444 0.25 ENSDART00000141682
nudt3a
nudix (nucleoside diphosphate linked moiety X)-type motif 3a
chr6_-_49861506 0.25 ENSDART00000121809
gnas
GNAS complex locus
chr18_-_43993614 0.24 ENSDART00000148535
ENSDART00000077357
bcl9l
B cell CLL/lymphoma 9-like
chr7_-_33351485 0.24 ENSDART00000146420
anp32a
acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
chr24_+_30215475 0.24 ENSDART00000164717
si:ch73-358j7.2
si:ch73-358j7.2
chr3_-_31069776 0.24 ENSDART00000167462
elob
elongin B
chr21_-_27881752 0.23 ENSDART00000132583
nrxn2a
neurexin 2a
chr23_+_25832689 0.23 ENSDART00000138907
hnf4a
hepatocyte nuclear factor 4, alpha
chr13_-_24877577 0.23 ENSDART00000182705
kat6b
K(lysine) acetyltransferase 6B
chr8_-_4010887 0.22 ENSDART00000163678
mtmr3
myotubularin related protein 3
chr12_-_43428542 0.22 ENSDART00000192266
ptprea
protein tyrosine phosphatase, receptor type, E, a
chr19_-_27391179 0.22 ENSDART00000181108
mgat1b
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase b
chr18_-_37007061 0.19 ENSDART00000136432
map3k10
mitogen-activated protein kinase kinase kinase 10
chr24_+_28561038 0.18 ENSDART00000147063
abca4a
ATP-binding cassette, sub-family A (ABC1), member 4a
chr3_-_31057624 0.18 ENSDART00000152901
armc5
armadillo repeat containing 5
chr4_+_13810811 0.18 ENSDART00000067168
pdzrn4
PDZ domain containing ring finger 4
chr5_-_61652254 0.17 ENSDART00000097364
drl
draculin
chr21_+_22878991 0.17 ENSDART00000186399
pcf11
PCF11 cleavage and polyadenylation factor subunit
chr13_-_40141630 0.17 ENSDART00000181618
ENSDART00000171583
ENSDART00000192780
crtac1b
cartilage acidic protein 1b
chr19_-_32641725 0.16 ENSDART00000165006
ENSDART00000188185
hpca
hippocalcin
chr1_+_37391716 0.16 ENSDART00000191986
sparcl1
SPARC-like 1
chr17_-_25737452 0.15 ENSDART00000152021
si:ch211-214p16.3
si:ch211-214p16.3
chr6_-_7052595 0.15 ENSDART00000081761
ENSDART00000181351
bin1b
bridging integrator 1b
chr5_-_14211487 0.15 ENSDART00000135731
npffr1l2
neuropeptide FF receptor 1 like 2
chr7_+_32605705 0.13 ENSDART00000173841
fshb
follicle stimulating hormone, beta polypeptide
chr21_-_20342096 0.13 ENSDART00000065659
rbp4l
retinol binding protein 4, like
chr5_-_28102698 0.13 ENSDART00000138140
si:ch211-48m9.1
si:ch211-48m9.1
chr4_-_9214288 0.12 ENSDART00000067309
avpr1ab
arginine vasopressin receptor 1Ab
chr17_+_43623598 0.12 ENSDART00000154138
znf365
zinc finger protein 365
chr9_+_50000504 0.11 ENSDART00000164409
ENSDART00000165451
ENSDART00000166509
slc38a11
solute carrier family 38, member 11
chr3_-_60142530 0.11 ENSDART00000153247
si:ch211-120g10.1
si:ch211-120g10.1
chr20_+_22130284 0.11 ENSDART00000025575
clocka
clock circadian regulator a
chr8_+_35664152 0.11 ENSDART00000144520
si:dkeyp-14d3.1
si:dkeyp-14d3.1
chr18_+_642889 0.10 ENSDART00000189007
CABZ01078320.1

chr13_-_30713236 0.10 ENSDART00000112372
ENSDART00000142221
tmem72
transmembrane protein 72
chr8_+_37168570 0.10 ENSDART00000098636
csf1b
colony stimulating factor 1b (macrophage)
chr17_+_41081977 0.09 ENSDART00000137091
ENSDART00000143714
babam2
BRISC and BRCA1 A complex member 2
chr22_-_4784658 0.09 ENSDART00000140839
CU570881.1

chr1_-_9249943 0.09 ENSDART00000055011
zgc:136472
zgc:136472
chr21_-_20341836 0.09 ENSDART00000176689
rbp4l
retinol binding protein 4, like
chr1_+_57041549 0.08 ENSDART00000152198
si:ch211-1f22.16
si:ch211-1f22.16
chr2_-_6262441 0.08 ENSDART00000092190
arl14
ADP-ribosylation factor-like 14
chr3_+_39958407 0.08 ENSDART00000099754
ccdc97
coiled-coil domain containing 97
chr15_-_26552652 0.08 ENSDART00000152336
serpinf2b
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2b
chr15_-_5467477 0.08 ENSDART00000123839
arrb1
arrestin, beta 1
chr7_-_8168535 0.07 ENSDART00000173008
si:ch211-163c2.3
si:ch211-163c2.3
chr15_+_41901970 0.07 ENSDART00000152724
si:ch211-191a16.5
si:ch211-191a16.5
chr4_-_5291256 0.07 ENSDART00000150864
SNAP91 (1 of many)
si:ch211-214j24.9
chr19_+_19512515 0.07 ENSDART00000180065
jazf1a
JAZF zinc finger 1a
chr4_-_8903240 0.07 ENSDART00000129983
mpped1
metallophosphoesterase domain containing 1
chr3_-_28120092 0.07 ENSDART00000151143
rbfox1
RNA binding fox-1 homolog 1
chr25_+_19955598 0.07 ENSDART00000091547
kcna1a
potassium voltage-gated channel, shaker-related subfamily, member 1a
chr21_-_41369370 0.06 ENSDART00000159290
cpeb4b
cytoplasmic polyadenylation element binding protein 4b
chr1_-_21287724 0.06 ENSDART00000193900
npy1r
neuropeptide Y receptor Y1
chr21_-_43482426 0.06 ENSDART00000192901
ankrd46a
ankyrin repeat domain 46a
chr11_+_43114108 0.06 ENSDART00000013642
ENSDART00000190266
foxg1b
forkhead box G1b
chr3_-_32071468 0.06 ENSDART00000121979
BX511080.1

chr4_+_44454270 0.05 ENSDART00000150482
si:dkeyp-100h4.4
si:dkeyp-100h4.4
chr5_-_67661102 0.05 ENSDART00000013605
zbtb20
zinc finger and BTB domain containing 20
chr3_-_22228602 0.05 ENSDART00000017750
myl4
myosin, light chain 4, alkali; atrial, embryonic
chr4_-_76488581 0.05 ENSDART00000174291
ftr51
finTRIM family, member 51
chr22_-_7129631 0.05 ENSDART00000171359
asic1b
acid-sensing (proton-gated) ion channel 1b
chr1_-_54191626 0.05 ENSDART00000062941
nthl1
nth-like DNA glycosylase 1
chr6_-_7052408 0.04 ENSDART00000150033
ENSDART00000149232
bin1b
bridging integrator 1b
chr18_-_20560007 0.04 ENSDART00000141367
ENSDART00000090186
si:ch211-238n5.4
si:ch211-238n5.4
chr7_-_71434298 0.04 ENSDART00000180507
lgi2a
leucine-rich repeat LGI family, member 2a
chr7_+_4922104 0.04 ENSDART00000135154
si:dkey-28d5.11
si:dkey-28d5.11
chr20_-_40754794 0.03 ENSDART00000187251
cx32.3
connexin 32.3
chr14_-_2348917 0.03 ENSDART00000159004
si:ch73-233f7.8
si:ch73-233f7.8
chr18_+_50276653 0.02 ENSDART00000192120
si:dkey-105e17.1
si:dkey-105e17.1
chr4_+_8016457 0.02 ENSDART00000014036
optn
optineurin
chr21_+_19525141 0.02 ENSDART00000058489
gzma
granzyme A
chr23_-_11128601 0.02 ENSDART00000131232
cntn3a.2
contactin 3a, tandem duplicate 2
chr14_-_1313480 0.02 ENSDART00000097748
il21
interleukin 21
chr1_-_21409877 0.02 ENSDART00000102782
gria2a
glutamate receptor, ionotropic, AMPA 2a
chr8_-_45279411 0.02 ENSDART00000175207
adamts13
ADAM metallopeptidase with thrombospondin type 1 motif, 13
chr3_-_34032019 0.02 ENSDART00000151779
ighv13-2
immunoglobulin heavy variable 13-2
chr7_+_25036188 0.02 ENSDART00000163957
ENSDART00000169749
sb:cb1058
sb:cb1058
chr4_-_31700186 0.01 ENSDART00000183986
ENSDART00000180890
si:dkey-16p6.1
si:dkey-16p6.1
chr13_+_36144341 0.01 ENSDART00000182930
ENSDART00000187327
TTC9
si:ch211-259k16.3
chr11_+_5817202 0.01 ENSDART00000126084
ctdspl3
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 3
chr17_-_45247332 0.01 ENSDART00000016815
ttbk2a
tau tubulin kinase 2a
chr8_+_20503842 0.01 ENSDART00000100328
csnk1g2b
casein kinase 1, gamma 2b

Network of associatons between targets according to the STRING database.

First level regulatory network of onecut2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0060631 regulation of meiosis I(GO:0060631)
0.4 2.1 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.4 1.2 GO:0071896 protein localization to adherens junction(GO:0071896)
0.3 1.0 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.3 0.8 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.3 1.0 GO:0051352 negative regulation of ligase activity(GO:0051352) negative regulation of ubiquitin-protein transferase activity(GO:0051444) negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.2 0.9 GO:0015887 biotin transport(GO:0015878) pantothenate transmembrane transport(GO:0015887) coenzyme transport(GO:0051182)
0.2 0.9 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.2 2.1 GO:0030210 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.2 2.7 GO:0019433 triglyceride catabolic process(GO:0019433)
0.2 0.9 GO:0071800 podosome assembly(GO:0071800)
0.1 0.8 GO:0060251 regulation of glial cell proliferation(GO:0060251)
0.1 0.8 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.1 2.1 GO:0097178 ruffle assembly(GO:0097178)
0.1 1.1 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.1 0.5 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.1 0.4 GO:0060220 retinal cone cell fate determination(GO:0042671) eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate determination(GO:0043703) retinal cone cell fate commitment(GO:0046551) photoreceptor cell fate commitment(GO:0046552) camera-type eye photoreceptor cell fate commitment(GO:0060220)
0.1 0.8 GO:0032024 positive regulation of insulin secretion(GO:0032024)
0.1 0.5 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.1 0.3 GO:0051972 regulation of telomerase activity(GO:0051972)
0.1 1.1 GO:0034625 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 0.5 GO:0045117 azole transport(GO:0045117)
0.0 0.2 GO:1901906 diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.0 0.2 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0 0.3 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.5 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.0 0.3 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.5 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.5 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.0 0.7 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.6 GO:0006688 glycosphingolipid biosynthetic process(GO:0006688)
0.0 0.4 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026) negative regulation of microtubule polymerization or depolymerization(GO:0031111)
0.0 0.7 GO:0006491 N-glycan processing(GO:0006491)
0.0 1.5 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.0 0.7 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.0 0.4 GO:0050728 negative regulation of inflammatory response(GO:0050728)
0.0 0.9 GO:0051209 release of sequestered calcium ion into cytosol(GO:0051209)
0.0 1.5 GO:0007338 single fertilization(GO:0007338)
0.0 0.5 GO:0007257 activation of JUN kinase activity(GO:0007257) positive regulation of JUN kinase activity(GO:0043507)
0.0 0.1 GO:1900120 microglial cell activation(GO:0001774) regulation of cytokine activity(GO:0060300) regulation of receptor binding(GO:1900120) regulation of chemokine activity(GO:1900136)
0.0 0.7 GO:0014866 skeletal myofibril assembly(GO:0014866)
0.0 0.1 GO:0030728 ovulation(GO:0030728)
0.0 0.3 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 0.7 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.3 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.0 0.2 GO:0070365 hepatocyte differentiation(GO:0070365)
0.0 0.3 GO:0016925 protein sumoylation(GO:0016925)
0.0 0.1 GO:0072401 signal transduction involved in DNA integrity checkpoint(GO:0072401) signal transduction involved in DNA damage checkpoint(GO:0072422) signal transduction involved in G2 DNA damage checkpoint(GO:0072425)
0.0 0.0 GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.0 0.1 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.0 0.3 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0018444 translation release factor complex(GO:0018444)
0.1 0.9 GO:0001891 phagocytic cup(GO:0001891)
0.1 0.5 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.1 2.1 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.1 1.0 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 2.1 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.4 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.5 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.2 GO:0030891 VCB complex(GO:0030891)
0.0 0.9 GO:0030667 secretory granule membrane(GO:0030667)
0.0 0.8 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.0 0.4 GO:0030904 retromer complex(GO:0030904)
0.0 0.1 GO:1990513 CLOCK-BMAL transcription complex(GO:1990513)
0.0 0.3 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.5 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.7 GO:0032156 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 2.4 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.3 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 1.0 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.3 GO:0000784 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783) nuclear chromosome, telomeric region(GO:0000784)
0.0 0.1 GO:0070552 BRISC complex(GO:0070552)
0.0 0.2 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 1.2 GO:0030027 lamellipodium(GO:0030027)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.1 GO:0047464 heparosan-N-sulfate-glucuronate 5-epimerase activity(GO:0047464)
0.3 0.8 GO:0061513 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.2 2.7 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.2 0.9 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.2 0.6 GO:0008489 UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity(GO:0008489)
0.2 1.1 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.1 0.5 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
0.1 0.5 GO:0052905 tRNA (guanine(9)-N(1))-methyltransferase activity(GO:0052905)
0.1 1.0 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.1 0.4 GO:0070324 thyroid hormone binding(GO:0070324)
0.1 0.9 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.1 0.7 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 0.9 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1 0.4 GO:0032052 bile acid binding(GO:0032052)
0.1 1.5 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 0.3 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.1 0.5 GO:1901474 azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.1 0.2 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.1 0.5 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.1 0.7 GO:0070740 protein-glutamic acid ligase activity(GO:0070739) tubulin-glutamic acid ligase activity(GO:0070740)
0.1 0.5 GO:0005042 netrin receptor activity(GO:0005042)
0.1 1.1 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.2 GO:0034432 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.0 0.2 GO:0051430 mu-type opioid receptor binding(GO:0031852) dopamine receptor binding(GO:0050780) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.0 0.3 GO:0004396 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) glucose binding(GO:0005536) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.5 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.0 0.1 GO:0030882 lipid antigen binding(GO:0030882)
0.0 0.8 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.6 GO:0030552 cAMP binding(GO:0030552)
0.0 0.4 GO:0030507 spectrin binding(GO:0030507)
0.0 0.2 GO:0048156 tau protein binding(GO:0048156)
0.0 0.2 GO:0034632 retinol transporter activity(GO:0034632)
0.0 2.1 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.3 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.2 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.3 GO:0031386 protein tag(GO:0031386)
0.0 1.5 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.3 GO:0031726 CCR1 chemokine receptor binding(GO:0031726) CCR4 chemokine receptor binding(GO:0031729)
0.0 0.9 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.3 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.3 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.8 GO:0005347 ATP transmembrane transporter activity(GO:0005347)
0.0 0.1 GO:0070888 E-box binding(GO:0070888)
0.0 0.0 GO:0000703 oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity(GO:0000703)
0.0 0.3 GO:0008378 galactosyltransferase activity(GO:0008378)
0.0 0.4 GO:0019003 GDP binding(GO:0019003)
0.0 0.1 GO:0005000 vasopressin receptor activity(GO:0005000)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.8 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.6 PID ARF 3PATHWAY Arf1 pathway
0.0 1.1 PID AURORA B PATHWAY Aurora B signaling
0.0 1.0 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.5 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 1.1 PID E2F PATHWAY E2F transcription factor network
0.0 0.5 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 2.1 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.1 1.7 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.8 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.5 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.5 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 1.7 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 1.5 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.5 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.3 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.7 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.1 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.2 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0 0.4 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels