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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for osr1

Z-value: 1.05

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Transcription factors associated with osr1

Gene Symbol Gene ID Gene Info
osr1
ENSDARG00000014091 odd-skipped related transcription factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
osr1dr11_v1_chr13_+_32148338_321483380.896.7e-07Click!

Activity profile of osr1 motif

Sorted Z-values of osr1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_34750169 4.19 ENSDART00000149380
si:dkey-151m22.8
si:dkey-151m22.8
chr2_-_49557932 4.00 ENSDART00000141902
si:ch211-209f23.3
si:ch211-209f23.3
chr5_-_61787969 3.50 ENSDART00000112744
gas2l2
growth arrest specific 2 like 2
chr3_+_15805917 3.33 ENSDART00000055834
phospho1
phosphatase, orphan 1
chr18_-_29961784 3.00 ENSDART00000135601
ENSDART00000140661
si:ch73-103b9.2
si:ch73-103b9.2
chr2_-_43942595 2.81 ENSDART00000147925
si:ch211-195h23.4
si:ch211-195h23.4
chr2_+_49799470 2.77 ENSDART00000146325
si:ch211-190k17.19
si:ch211-190k17.19
chr7_+_24391129 2.77 ENSDART00000108753
poln
polymerase (DNA directed) nu
chr18_+_46382484 2.65 ENSDART00000024202
ENSDART00000142790
daw1
dynein assembly factor with WDR repeat domains 1
chr10_+_2587234 2.54 ENSDART00000126937
wu:fb59d01
wu:fb59d01
chr12_-_2993095 2.37 ENSDART00000152316
si:dkey-202c14.3
si:dkey-202c14.3
chr21_+_4702773 2.36 ENSDART00000147404
si:dkey-102g19.3
si:dkey-102g19.3
chr22_-_28871787 2.28 ENSDART00000104828
gtpbp2b
GTP binding protein 2b
chr5_-_36949476 2.20 ENSDART00000047269
h3f3c
H3 histone, family 3C
chr23_-_42752550 2.17 ENSDART00000187059
si:ch73-217n20.1
si:ch73-217n20.1
chr23_-_42752387 2.15 ENSDART00000149781
si:ch73-217n20.1
si:ch73-217n20.1
chr4_-_8040436 2.14 ENSDART00000113033
si:ch211-240l19.6
si:ch211-240l19.6
chr14_+_4151379 1.95 ENSDART00000160431
dhrs13l1
dehydrogenase/reductase (SDR family) member 13 like 1
chr2_+_56463167 1.92 ENSDART00000123392
rab11bb
RAB11B, member RAS oncogene family, b
chr22_-_21314821 1.91 ENSDART00000105546
ENSDART00000135388
cks2
CDC28 protein kinase regulatory subunit 2
chr20_-_2667902 1.90 ENSDART00000036373
cfap206
cilia and flagella associated protein 206
chr8_-_24332284 1.86 ENSDART00000163241
pimr142
Pim proto-oncogene, serine/threonine kinase, related 142
chr2_+_22531185 1.85 ENSDART00000171959
hfm1
HFM1, ATP-dependent DNA helicase homolog (S. cerevisiae)
chr7_-_41295511 1.85 ENSDART00000173455
si:dkey-86l18.8
si:dkey-86l18.8
chr7_-_52388090 1.71 ENSDART00000174104
wdr93
WD repeat domain 93
chr8_-_24502997 1.69 ENSDART00000184801
ENSDART00000179794
BX296549.1

chr20_-_29787192 1.69 ENSDART00000125348
ENSDART00000048759
id2b
inhibitor of DNA binding 2b
chr25_+_32530976 1.68 ENSDART00000156190
ENSDART00000103324
scaper
S-phase cyclin A-associated protein in the ER
chr2_-_24898226 1.65 ENSDART00000134936
si:dkey-149i17.9
si:dkey-149i17.9
chr11_+_26604224 1.65 ENSDART00000030453
ENSDART00000168895
ENSDART00000159505
dynlrb1
dynein, light chain, roadblock-type 1
chr7_+_26534131 1.63 ENSDART00000173980
si:dkey-62k3.5
si:dkey-62k3.5
chr19_+_31576849 1.60 ENSDART00000134107
ENSDART00000088401
acot13
acyl-CoA thioesterase 13
chr7_-_52388734 1.59 ENSDART00000174186
wdr93
WD repeat domain 93
chr15_-_32383529 1.56 ENSDART00000028349
c4
complement component 4
chr2_-_37896965 1.55 ENSDART00000129852
hbl1
hexose-binding lectin 1
chr8_-_36554675 1.55 ENSDART00000132804
ENSDART00000078746
ccdc157
coiled-coil domain containing 157
chr16_-_7214513 1.52 ENSDART00000150005
si:ch73-341k19.1
si:ch73-341k19.1
chr6_+_46431848 1.48 ENSDART00000181056
ENSDART00000144569
ENSDART00000064865
ENSDART00000133992
stau1
staufen double-stranded RNA binding protein 1
chr12_-_38548299 1.48 ENSDART00000153374
si:dkey-1f1.3
si:dkey-1f1.3
chr8_-_24697586 1.47 ENSDART00000188639
BX324132.4

chr14_+_17137023 1.46 ENSDART00000080712
slc43a3b
solute carrier family 43, member 3b
chr7_+_44713135 1.44 ENSDART00000170721
si:dkey-56m19.5
si:dkey-56m19.5
chr15_-_39848822 1.44 ENSDART00000155230
si:dkey-263j23.1
si:dkey-263j23.1
chr10_-_25860102 1.44 ENSDART00000080789
trpc4a
transient receptor potential cation channel, subfamily C, member 4a
chr8_-_24366726 1.43 ENSDART00000182351
ENSDART00000187099
ENSDART00000181534
CR450805.1

chr24_-_9960290 1.42 ENSDART00000143390
ENSDART00000092975
ENSDART00000184953
vps41
vacuolar protein sorting 41 homolog (S. cerevisiae)
chr13_+_9213805 1.42 ENSDART00000131455
pimr158
Pim proto-oncogene, serine/threonine kinase, related 158
chr14_-_24391424 1.38 ENSDART00000113376
ENSDART00000126894
fam13b
family with sequence similarity 13, member B
chr5_+_26847190 1.38 ENSDART00000076742
imp4
IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast)
chr1_+_44767657 1.36 ENSDART00000073717
si:dkey-9i23.4
si:dkey-9i23.4
chr5_+_69747417 1.35 ENSDART00000153717
si:ch211-275j6.5
si:ch211-275j6.5
chr20_+_1412193 1.35 ENSDART00000064419
leg1.1
liver-enriched gene 1, tandem duplicate 1
chr3_-_30123113 1.34 ENSDART00000153562
ppfia3
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
chr2_+_3986083 1.33 ENSDART00000188979
mkxb
mohawk homeobox b
chr8_+_50493095 1.32 ENSDART00000108655
ENSDART00000134382
si:dkey-263f15.2
si:dkey-263f15.2
chr3_-_37758487 1.32 ENSDART00000150938
si:dkey-260c8.6
si:dkey-260c8.6
chr14_+_21038462 1.31 ENSDART00000162999
pimr193
Pim proto-oncogene, serine/threonine kinase, related 193
chr6_-_52723901 1.31 ENSDART00000033949
oser1
oxidative stress responsive serine-rich 1
chr10_-_34089779 1.28 ENSDART00000140070
pimr144
Pim proto-oncogene, serine/threonine kinase, related 144
chr3_-_16285861 1.25 ENSDART00000140103
bckdhbl
branched chain keto acid dehydrogenase E1, beta polypeptide, like
chr3_-_29899172 1.24 ENSDART00000140518
ENSDART00000020311
rpl27
ribosomal protein L27
chr4_+_3287819 1.23 ENSDART00000168633
CABZ01085700.1

chr7_+_29954709 1.23 ENSDART00000173904
tpma
alpha-tropomyosin
chr16_+_53489676 1.21 ENSDART00000074653
grinab
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1b (glutamate binding)
chr7_-_27033080 1.21 ENSDART00000173516
nucb2a
nucleobindin 2a
chr3_-_45298487 1.20 ENSDART00000102245
pdpk1a
3-phosphoinositide dependent protein kinase 1a
chr10_+_38512270 1.20 ENSDART00000109752
serpinh1a
serpin peptidase inhibitor, clade H (heat shock protein 47), member 1a
chr8_+_4798158 1.19 ENSDART00000031650
hsp70l
heat shock cognate 70-kd protein, like
chr6_+_49082796 1.15 ENSDART00000182446
tshba
thyroid stimulating hormone, beta subunit, a
chr14_+_35901249 1.08 ENSDART00000105604
zgc:77938
zgc:77938
chr10_-_34107919 1.03 ENSDART00000167428
ENSDART00000145279
pimr144
pimr146
Pim proto-oncogene, serine/threonine kinase, related 144
Pim proto-oncogene, serine/threonine kinase, related 146
chr10_-_34223567 1.03 ENSDART00000184889
pimr145
Pim proto-oncogene, serine/threonine kinase, related 145
chr23_+_7379728 1.02 ENSDART00000012194
gata5
GATA binding protein 5
chr8_-_50981175 1.00 ENSDART00000004065
zgc:91909
zgc:91909
chr21_+_33454147 1.00 ENSDART00000053208
rps14
ribosomal protein S14
chr5_-_30978381 0.96 ENSDART00000127787
spns3
spinster homolog 3 (Drosophila)
chr20_+_16881883 0.95 ENSDART00000130107
nfkbiaa
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a
chr20_+_53521648 0.93 ENSDART00000139794
pak6b
p21 protein (Cdc42/Rac)-activated kinase 6b
chr10_-_34067286 0.93 ENSDART00000140730
BX548044.8

chr3_-_55139127 0.93 ENSDART00000115324
hbae1.3
hemoglobin, alpha embryonic 1.3
chr14_+_29769336 0.92 ENSDART00000105898
si:dkey-34l15.1
si:dkey-34l15.1
chr23_+_4324625 0.87 ENSDART00000146302
ENSDART00000136792
ENSDART00000135027
ENSDART00000179819
sgk2a
serum/glucocorticoid regulated kinase 2a
chr4_-_67969695 0.86 ENSDART00000190016
si:ch211-223k15.1
si:ch211-223k15.1
chr25_+_7670683 0.86 ENSDART00000040275
kcnj11l
potassium inwardly-rectifying channel, subfamily J, member 11, like
chr12_+_36413886 0.86 ENSDART00000126325
si:ch211-250n8.1
si:ch211-250n8.1
chr19_+_26714949 0.85 ENSDART00000188540
zgc:100906
zgc:100906
chr23_+_24604481 0.85 ENSDART00000146332
kansl2
KAT8 regulatory NSL complex subunit 2
chr2_-_20574193 0.85 ENSDART00000190448
si:ch211-267e7.3
si:ch211-267e7.3
chr21_-_25250594 0.85 ENSDART00000163862
nfrkb
nuclear factor related to kappaB binding protein
chr2_-_24962820 0.83 ENSDART00000182767
hltf
helicase-like transcription factor
chr5_-_48307804 0.82 ENSDART00000182831
ENSDART00000186920
ENSDART00000183585
mef2cb
myocyte enhancer factor 2cb
chr9_-_306515 0.82 ENSDART00000166059
si:ch211-166e11.5
si:ch211-166e11.5
chr18_+_45676788 0.81 ENSDART00000109948
ENSDART00000179864
qser1
glutamine and serine rich 1
chr7_+_22767678 0.81 ENSDART00000137203
ponzr6
plac8 onzin related protein 6
chr8_-_36469117 0.80 ENSDART00000111240
mhc2dab
major histocompatibility complex class II DAB gene
chr1_+_52563298 0.80 ENSDART00000142465
abca1a
ATP-binding cassette, sub-family A (ABC1), member 1A
chr8_-_2506327 0.79 ENSDART00000101125
ENSDART00000125124
rpl6
ribosomal protein L6
chr13_-_46917098 0.78 ENSDART00000183453
slc29a1a
solute carrier family 29 (equilibrative nucleoside transporter), member 1a
chr9_-_12424231 0.77 ENSDART00000188952
zgc:162707
zgc:162707
chr1_-_31657854 0.73 ENSDART00000085309
dpcd
deleted in primary ciliary dyskinesia homolog (mouse)
chr19_-_26823647 0.73 ENSDART00000002464
neu1
neuraminidase 1
chr6_-_40884453 0.73 ENSDART00000017968
ENSDART00000154100
sirt4
sirtuin 4
chr4_-_1824836 0.72 ENSDART00000111858
mrpl42
mitochondrial ribosomal protein L42
chr2_-_30668580 0.72 ENSDART00000087270
ctnnd2b
catenin (cadherin-associated protein), delta 2b
chr14_-_26536504 0.72 ENSDART00000105933
tgfbi
transforming growth factor, beta-induced
chr17_-_22021213 0.72 ENSDART00000078843
zmp:0000001102
zmp:0000001102
chr7_+_17374560 0.71 ENSDART00000172272
ENSDART00000073467
nitr7a
novel immune-type receptor 7a
chr12_-_7824291 0.71 ENSDART00000148673
ENSDART00000149453
ank3b
ankyrin 3b
chr18_+_20869923 0.70 ENSDART00000138471
pgpep1l
pyroglutamyl-peptidase I-like
chr4_+_47257854 0.70 ENSDART00000173868
crestin
crestin
chr15_-_576135 0.70 ENSDART00000124170
cbln20
cerebellin 20
chr23_-_31403668 0.69 ENSDART00000147498
CR759830.1

chr18_-_46258612 0.68 ENSDART00000153930
si:dkey-244a7.1
si:dkey-244a7.1
chr11_-_24347644 0.68 ENSDART00000089777
si:ch211-15p9.2
si:ch211-15p9.2
chr4_-_6567355 0.67 ENSDART00000134820
ENSDART00000142087
foxp2
forkhead box P2
chr16_-_28876479 0.67 ENSDART00000047862
si:dkey-239n17.4
si:dkey-239n17.4
chr8_-_7475917 0.66 ENSDART00000082157
gata1b
GATA binding protein 1b
chr5_-_57169604 0.66 ENSDART00000136232
si:dkey-79c1.1
si:dkey-79c1.1
chr5_+_69808763 0.66 ENSDART00000143482
fsd1l
fibronectin type III and SPRY domain containing 1-like
chr4_-_12323228 0.66 ENSDART00000081089
il17ra1a
interleukin 17 receptor A1a
chr8_-_25728628 0.65 ENSDART00000127237
foxp3a
forkhead box P3a
chr13_-_32635859 0.64 ENSDART00000146249
ENSDART00000145395
ENSDART00000148040
ENSDART00000100650
matn3b
matrilin 3b
chr5_+_13373593 0.64 ENSDART00000051668
ENSDART00000183883
ccl19a.2
chemokine (C-C motif) ligand 19a, tandem duplicate 2
chr8_+_48858132 0.63 ENSDART00000124737
ENSDART00000079644
tp73
tumor protein p73
chr19_+_10794072 0.63 ENSDART00000151518
ENSDART00000142614
lipea
lipase, hormone-sensitive a
chr14_-_40390757 0.63 ENSDART00000149443
pcdh19
protocadherin 19
chr11_+_14199802 0.62 ENSDART00000102520
ENSDART00000133172
palm1a
paralemmin 1a
chr6_+_52947186 0.61 ENSDART00000155831
uba7
ubiquitin-like modifier activating enzyme 7
chr3_-_16784280 0.61 ENSDART00000137108
ENSDART00000137276
si:dkey-30j10.5
si:dkey-30j10.5
chr7_+_3872189 0.61 ENSDART00000064221
si:dkey-88n24.5
si:dkey-88n24.5
chr13_-_45523026 0.59 ENSDART00000020663
rhd
Rh blood group, D antigen
chr22_-_11626014 0.58 ENSDART00000063133
ENSDART00000160085
gcga
glucagon a
chr18_+_7204378 0.58 ENSDART00000142905
vwf
von Willebrand factor
chr12_-_18898413 0.58 ENSDART00000181281
ENSDART00000121866
desi1b
desumoylating isopeptidase 1b
chr18_+_30507839 0.57 ENSDART00000026866
cox4i1
cytochrome c oxidase subunit IV isoform 1
chr15_-_32383340 0.57 ENSDART00000185632
c4
complement component 4
chr22_-_16658996 0.57 ENSDART00000138429
si:dkey-38n4.2
si:dkey-38n4.2
chr18_-_977075 0.56 ENSDART00000032392
dhdhl
dihydrodiol dehydrogenase (dimeric), like
chr11_-_33960318 0.55 ENSDART00000087597
col6a2
collagen, type VI, alpha 2
chr17_-_50422584 0.55 ENSDART00000157095
si:ch211-235i11.5
si:ch211-235i11.5
chr1_+_23783349 0.54 ENSDART00000007531
slit2
slit homolog 2 (Drosophila)
chr7_-_18508815 0.54 ENSDART00000173539
rgs12a
regulator of G protein signaling 12a
chr7_+_48805534 0.54 ENSDART00000145375
ENSDART00000148744
cpt1aa
carnitine palmitoyltransferase 1Aa (liver)
chr10_+_19554604 0.54 ENSDART00000063806
atp6v1b2
ATPase H+ transporting V1 subunit B2
chr13_+_35746440 0.54 ENSDART00000187859
gpr75
G protein-coupled receptor 75
chr11_-_36350876 0.53 ENSDART00000146495
ENSDART00000020655
psma5
proteasome subunit alpha 5
chr7_-_17600415 0.52 ENSDART00000080717
nitr6b
novel immune-type receptor 6b
chr2_-_9748039 0.51 ENSDART00000134870
si:ch1073-170o4.1
si:ch1073-170o4.1
chr2_+_37897079 0.51 ENSDART00000141784
tep1
telomerase-associated protein 1
chr9_-_18568927 0.50 ENSDART00000084668
enox1
ecto-NOX disulfide-thiol exchanger 1
chr10_+_33744098 0.50 ENSDART00000147775
rxfp2a
relaxin/insulin-like family peptide receptor 2a
chr5_+_30682737 0.50 ENSDART00000172886
pdzd3b
PDZ domain containing 3b
chr1_-_21723329 0.49 ENSDART00000137138
si:ch211-134c9.2
si:ch211-134c9.2
chr7_-_59564011 0.49 ENSDART00000186053
zgc:112271
zgc:112271
chr18_-_49116382 0.48 ENSDART00000174157
BX663503.3

chr7_-_55292116 0.48 ENSDART00000122603
rnf166
ring finger protein 166
chr14_+_33955807 0.48 ENSDART00000173316
si:ch73-22o18.1
si:ch73-22o18.1
chr23_+_43809484 0.48 ENSDART00000149534
si:ch211-149b19.3
si:ch211-149b19.3
chr12_-_15620090 0.47 ENSDART00000038032
acbd4
acyl-CoA binding domain containing 4
chr11_-_29996344 0.47 ENSDART00000003712
ENSDART00000126110
ace2
angiotensin I converting enzyme 2
chr6_-_8498908 0.46 ENSDART00000149222
pglyrp2
peptidoglycan recognition protein 2
chr16_+_35344031 0.46 ENSDART00000167140
si:dkey-34d22.1
si:dkey-34d22.1
chr19_-_9503473 0.45 ENSDART00000091615
iffo1a
intermediate filament family orphan 1a
chr22_-_26323893 0.45 ENSDART00000105099
capn1b
calpain 1, (mu/I) large subunit b
chr25_+_35212919 0.45 ENSDART00000180127
ano5a
anoctamin 5a
chr7_-_17635717 0.45 ENSDART00000080704
nitr6b
novel immune-type receptor 6b
chr17_-_14451405 0.45 ENSDART00000146786
jkamp
jnk1/mapk8 associated membrane protein
chr19_-_6134802 0.45 ENSDART00000140051
cica
capicua transcriptional repressor a
chr25_+_20119466 0.45 ENSDART00000104304
bpgm
2,3-bisphosphoglycerate mutase
chr10_-_31016806 0.43 ENSDART00000027288
panx3
pannexin 3
chr12_-_45669050 0.43 ENSDART00000124455
fbxl15
F-box and leucine-rich repeat protein 15
chr7_-_60156409 0.43 ENSDART00000006802
cct7
chaperonin containing TCP1, subunit 7 (eta)
chr18_-_29977431 0.43 ENSDART00000135357
si:ch211-220f16.2
si:ch211-220f16.2
chr13_+_28417297 0.43 ENSDART00000043658
slc2a15a
solute carrier family 2 (facilitated glucose transporter), member 15a
chr11_-_41130239 0.42 ENSDART00000173268
dnajc11b
DnaJ (Hsp40) homolog, subfamily C, member 11b
chr2_-_11512819 0.42 ENSDART00000142013
penka
proenkephalin a
chr13_-_1408775 0.42 ENSDART00000049684
bag2
BCL2 associated athanogene 2
chr21_+_45627775 0.42 ENSDART00000185466
irf1b
interferon regulatory factor 1b
chr14_-_13048355 0.41 ENSDART00000166434
si:dkey-35h6.1
si:dkey-35h6.1
chr10_-_22506044 0.41 ENSDART00000100497
zgc:172339
zgc:172339
chr24_+_10413484 0.41 ENSDART00000111014
myca
MYC proto-oncogene, bHLH transcription factor a
chr14_+_8504410 0.40 ENSDART00000123364
vegfba
vascular endothelial growth factor Ba
chr3_-_15144067 0.39 ENSDART00000127738
ENSDART00000060426
ENSDART00000180799
fam173a
family with sequence similarity 173, member A
chr1_+_55643198 0.39 ENSDART00000060693
adgre7
adhesion G protein-coupled receptor E7
chr15_-_35960250 0.39 ENSDART00000186765
col4a4
collagen, type IV, alpha 4
chr16_-_27749172 0.39 ENSDART00000145198
steap4
STEAP family member 4
chr1_-_9134045 0.39 ENSDART00000142132
palb2
partner and localizer of BRCA2
chr12_-_48467733 0.38 ENSDART00000153126
ENSDART00000152895
ENSDART00000014190
sec31b
SEC31 homolog B, COPII coat complex component
chr20_+_53522059 0.38 ENSDART00000147570
pak6b
p21 protein (Cdc42/Rac)-activated kinase 6b
chr7_-_38806186 0.38 ENSDART00000173669
atg13
ATG13 autophagy related 13 homolog (S. cerevisiae)
chr7_+_50464500 0.37 ENSDART00000191356
serinc4
serine incorporator 4
chr10_+_21559605 0.37 ENSDART00000123648
ENSDART00000108584
pcdh1a3
pcdh1a3
protocadherin 1 alpha 3
protocadherin 1 alpha 3
chr2_-_22363460 0.37 ENSDART00000158486
selenof
selenoprotein F
chr6_+_52947699 0.37 ENSDART00000180913
uba7
ubiquitin-like modifier activating enzyme 7
chr7_+_31871830 0.36 ENSDART00000139899
mybpc3
myosin binding protein C, cardiac
chr1_-_40911332 0.35 ENSDART00000027463
hmx4
H6 family homeobox 4
chr13_+_18663600 0.34 ENSDART00000141647
selenou1a
selenoprotein U 1a
chr8_+_30709685 0.34 ENSDART00000133989
upb1
ureidopropionase, beta
chr4_-_75158035 0.34 ENSDART00000174353
CABZ01066312.1

chr7_+_20656942 0.33 ENSDART00000100898
tnfsf12
TNF superfamily member 12

Network of associatons between targets according to the STRING database.

First level regulatory network of osr1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.8 GO:0070987 error-free translesion synthesis(GO:0070987)
0.3 1.9 GO:0003356 regulation of cilium beat frequency(GO:0003356)
0.3 0.9 GO:1901533 negative regulation of hematopoietic progenitor cell differentiation(GO:1901533)
0.3 1.0 GO:0048618 post-embryonic foregut morphogenesis(GO:0048618)
0.2 0.7 GO:0009595 detection of biotic stimulus(GO:0009595) detection of bacterium(GO:0016045) detection of other organism(GO:0098543) detection of external biotic stimulus(GO:0098581)
0.2 3.5 GO:0051764 actin crosslink formation(GO:0051764)
0.2 0.8 GO:0010874 regulation of cholesterol efflux(GO:0010874)
0.2 0.5 GO:0007414 axonal defasciculation(GO:0007414)
0.2 1.4 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.2 2.7 GO:0001539 cilium or flagellum-dependent cell motility(GO:0001539) cilium-dependent cell motility(GO:0060285)
0.2 0.7 GO:1904184 regulation of pyruvate dehydrogenase activity(GO:1904182) positive regulation of pyruvate dehydrogenase activity(GO:1904184)
0.2 1.1 GO:0046292 formaldehyde metabolic process(GO:0046292) formaldehyde catabolic process(GO:0046294)
0.1 1.3 GO:1990402 embryonic liver development(GO:1990402)
0.1 0.8 GO:0015864 uridine transport(GO:0015862) pyrimidine nucleoside transport(GO:0015864)
0.1 1.2 GO:0032096 negative regulation of response to food(GO:0032096) negative regulation of appetite(GO:0032099)
0.1 3.3 GO:0070167 regulation of bone mineralization(GO:0030500) regulation of biomineral tissue development(GO:0070167)
0.1 1.3 GO:0070301 cellular response to hydrogen peroxide(GO:0070301)
0.1 1.9 GO:0042574 retinal metabolic process(GO:0042574)
0.1 0.5 GO:0007624 ultradian rhythm(GO:0007624)
0.1 0.4 GO:0015677 copper ion import(GO:0015677)
0.1 0.3 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.1 1.2 GO:0042026 protein refolding(GO:0042026)
0.1 0.3 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.1 0.6 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.1 0.7 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998)
0.1 0.4 GO:0003210 cardiac atrium formation(GO:0003210)
0.1 1.7 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.1 0.3 GO:0019483 beta-alanine metabolic process(GO:0019482) beta-alanine biosynthetic process(GO:0019483)
0.1 1.4 GO:0006415 translational termination(GO:0006415)
0.1 0.4 GO:0032732 positive regulation of interleukin-1 production(GO:0032732)
0.1 0.7 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.1 0.2 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.1 3.9 GO:0022900 electron transport chain(GO:0022900)
0.1 0.5 GO:0015746 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.0 0.1 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.0 0.4 GO:0000423 macromitophagy(GO:0000423)
0.0 0.2 GO:0070227 lymphocyte apoptotic process(GO:0070227) leukocyte apoptotic process(GO:0071887)
0.0 0.1 GO:0099551 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551) cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.0 0.9 GO:0015671 oxygen transport(GO:0015671)
0.0 1.0 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.8 GO:0048512 rhythmic behavior(GO:0007622) circadian behavior(GO:0048512)
0.0 0.7 GO:0045471 response to ethanol(GO:0045471)
0.0 1.6 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.4 GO:0060753 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0 0.5 GO:0007190 activation of adenylate cyclase activity(GO:0007190) positive regulation of cAMP metabolic process(GO:0030816) positive regulation of cAMP biosynthetic process(GO:0030819) positive regulation of adenylate cyclase activity(GO:0045762)
0.0 2.3 GO:0006414 translational elongation(GO:0006414)
0.0 0.6 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 1.7 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.0 0.4 GO:0050688 regulation of defense response to virus(GO:0050688)
0.0 0.2 GO:0042983 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.0 0.8 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.2 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 0.4 GO:0042407 cristae formation(GO:0042407)
0.0 0.3 GO:1900052 regulation of isoprenoid metabolic process(GO:0019747) regulation of vitamin metabolic process(GO:0030656) regulation of retinoic acid biosynthetic process(GO:1900052)
0.0 2.1 GO:0006956 complement activation(GO:0006956)
0.0 9.6 GO:0046777 protein autophosphorylation(GO:0046777)
0.0 1.2 GO:1901215 negative regulation of neuron death(GO:1901215)
0.0 0.7 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.0 0.2 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.8 GO:0019882 antigen processing and presentation(GO:0019882)
0.0 0.5 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.7 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 0.2 GO:1904071 presynaptic active zone assembly(GO:1904071)
0.0 0.8 GO:0060914 heart formation(GO:0060914)
0.0 0.5 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.4 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.6 GO:0048854 brain morphogenesis(GO:0048854)
0.0 0.1 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.6 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.0 0.4 GO:0030513 bone mineralization(GO:0030282) positive regulation of BMP signaling pathway(GO:0030513)
0.0 1.3 GO:0071560 transforming growth factor beta receptor signaling pathway(GO:0007179) response to transforming growth factor beta(GO:0071559) cellular response to transforming growth factor beta stimulus(GO:0071560)
0.0 0.0 GO:0072068 distal convoluted tubule development(GO:0072025) late distal convoluted tubule development(GO:0072068)
0.0 0.7 GO:0051262 protein tetramerization(GO:0051262)
0.0 2.3 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.0 0.4 GO:0050821 protein stabilization(GO:0050821)
0.0 1.2 GO:0009755 hormone-mediated signaling pathway(GO:0009755)
0.0 0.9 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.0 0.2 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.0 0.5 GO:0006986 response to unfolded protein(GO:0006986)
0.0 1.3 GO:0099643 neurotransmitter secretion(GO:0007269) signal release from synapse(GO:0099643)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:0001534 radial spoke(GO:0001534)
0.5 1.4 GO:0034457 Mpp10 complex(GO:0034457)
0.4 1.2 GO:0098556 cytoplasmic side of rough endoplasmic reticulum membrane(GO:0098556)
0.2 1.4 GO:0030897 HOPS complex(GO:0030897)
0.1 1.7 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 1.2 GO:0008180 COP9 signalosome(GO:0008180)
0.1 0.8 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 0.4 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.1 3.4 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 0.9 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.1 0.3 GO:1990923 PET complex(GO:1990923)
0.1 0.2 GO:0097268 cytoophidium(GO:0097268)
0.1 0.8 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.5 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.6 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 5.0 GO:0005884 actin filament(GO:0005884)
0.0 1.9 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.4 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.4 GO:0061617 MICOS complex(GO:0061617)
0.0 0.1 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.0 0.5 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.2 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.1 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.0 0.4 GO:0005921 gap junction(GO:0005921)
0.0 1.0 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 1.9 GO:0055037 recycling endosome(GO:0055037)
0.0 1.2 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.2 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.2 GO:0098982 GABA-ergic synapse(GO:0098982)
0.0 1.3 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.6 GO:0005901 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 0.1 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.2 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.4 GO:0043679 axon terminus(GO:0043679)
0.0 0.8 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.1 GO:0030893 meiotic cohesin complex(GO:0030893)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0016920 pyroglutamyl-peptidase activity(GO:0016920)
0.2 3.5 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.2 0.7 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.2 1.1 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024) S-(hydroxymethyl)glutathione dehydrogenase activity(GO:0051903)
0.2 1.8 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.2 0.7 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.2 0.5 GO:0010852 cyclase inhibitor activity(GO:0010852) guanylate cyclase inhibitor activity(GO:0030251)
0.2 0.8 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012) phosphatidylcholine-translocating ATPase activity(GO:0090554) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.1 1.9 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.1 1.0 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.1 1.0 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.1 1.4 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.1 0.5 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.1 0.6 GO:0031769 glucagon receptor binding(GO:0031769)
0.1 0.7 GO:0016416 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.1 0.3 GO:0038046 enkephalin receptor activity(GO:0038046)
0.1 0.4 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.1 0.4 GO:0004619 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619)
0.1 1.2 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 0.6 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.1 0.9 GO:0031720 haptoglobin binding(GO:0031720)
0.1 0.4 GO:0008430 selenium binding(GO:0008430)
0.1 1.3 GO:0033691 sialic acid binding(GO:0033691)
0.1 1.4 GO:0030515 snoRNA binding(GO:0030515)
0.1 1.6 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.1 0.7 GO:0052794 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.1 0.9 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.1 0.8 GO:0002020 protease binding(GO:0002020)
0.1 0.2 GO:0003883 CTP synthase activity(GO:0003883)
0.1 0.7 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.1 1.7 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.1 2.3 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 5.9 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.7 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.1 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403) brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.0 0.4 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 3.3 GO:0016651 oxidoreductase activity, acting on NAD(P)H(GO:0016651)
0.0 0.3 GO:0034584 piRNA binding(GO:0034584)
0.0 0.4 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.9 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.2 GO:0048763 ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763)
0.0 0.2 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.0 0.1 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.5 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.4 GO:0031628 opioid receptor binding(GO:0031628)
0.0 0.4 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 2.8 GO:0004527 exonuclease activity(GO:0004527)
0.0 1.1 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.2 GO:0033781 cholesterol 24-hydroxylase activity(GO:0033781)
0.0 0.6 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.0 0.6 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.3 GO:0030546 receptor activator activity(GO:0030546) receptor agonist activity(GO:0048018)
0.0 0.7 GO:0005518 collagen binding(GO:0005518)
0.0 0.1 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.2 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.4 GO:0022829 wide pore channel activity(GO:0022829)
0.0 0.8 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.6 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.2 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 1.3 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.3 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.5 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.5 GO:0004180 carboxypeptidase activity(GO:0004180)
0.0 1.5 GO:0042803 protein homodimerization activity(GO:0042803)
0.0 0.1 GO:0051117 ATPase binding(GO:0051117)
0.0 0.2 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 1.9 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.5 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.9 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.2 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.7 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.3 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 0.6 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.5 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.3 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 1.0 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 3.0 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.9 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.3 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.2 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.2 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.4 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.3 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.4 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.5 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.5 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.7 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 1.4 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 1.0 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production