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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for otx5

Z-value: 0.82

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Transcription factors associated with otx5

Gene Symbol Gene ID Gene Info
otx5
ENSDARG00000043483 orthodenticle homolog 5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
otx5dr11_v1_chr15_+_47903864_47903864-0.931.5e-08Click!

Activity profile of otx5 motif

Sorted Z-values of otx5 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_4301234 3.70 ENSDART00000152377
ENSDART00000152521
ca15b
carbonic anhydrase XVb
chr4_-_77125693 3.30 ENSDART00000174256
CU467646.3

chr22_+_25140904 2.86 ENSDART00000143114
si:dkeyp-20e4.8
si:dkeyp-20e4.8
chr4_-_77130289 2.68 ENSDART00000174380
CU467646.7

chr23_-_45955177 1.92 ENSDART00000165963
ENSDART00000186649
ENSDART00000185773
LO017850.1

chr3_-_26184018 1.79 ENSDART00000191604
si:ch211-11k18.4
si:ch211-11k18.4
chr16_+_40043673 1.78 ENSDART00000102552
ENSDART00000125484
trmt11
tRNA methyltransferase 11 homolog (S. cerevisiae)
chr17_+_16046132 1.62 ENSDART00000155005
si:ch73-204p21.2
si:ch73-204p21.2
chr3_-_26183699 1.55 ENSDART00000147517
ENSDART00000140731
si:ch211-11k18.4
si:ch211-11k18.4
chr17_+_16046314 1.46 ENSDART00000154554
ENSDART00000154338
ENSDART00000155336
si:ch73-204p21.2
si:ch73-204p21.2
chr11_+_18037729 1.43 ENSDART00000111624
zgc:175135
zgc:175135
chr11_+_3499111 1.35 ENSDART00000113096
ENSDART00000171621
pusl1
pseudouridylate synthase-like 1
chr24_+_10898671 1.35 ENSDART00000106272
si:dkey-37o8.1
si:dkey-37o8.1
chr16_+_28547157 1.33 ENSDART00000109450
ENSDART00000165687
fam171a1
family with sequence similarity 171, member A1
chr24_+_36317544 1.31 ENSDART00000048640
ENSDART00000156096
pus3
pseudouridylate synthase 3
chr6_-_39521832 1.29 ENSDART00000065038
atf1
activating transcription factor 1
chr17_+_35097024 1.26 ENSDART00000026152
asap2a
ArfGAP with SH3 domain, ankyrin repeat and PH domain 2a
chr4_-_13614797 1.23 ENSDART00000138366
ENSDART00000165212
irf5
interferon regulatory factor 5
chr8_+_21297217 1.23 ENSDART00000142836
itpr3
inositol 1,4,5-trisphosphate receptor, type 3
chr5_-_4297459 1.20 ENSDART00000018895
srrt
serrate RNA effector molecule homolog (Arabidopsis)
chr14_-_41308561 1.18 ENSDART00000138232
arl13a
ADP-ribosylation factor-like 13A
chr6_-_17999776 1.17 ENSDART00000183048
ENSDART00000181577
ENSDART00000170597
rptor
regulatory associated protein of MTOR, complex 1
chr3_-_27647845 1.15 ENSDART00000151625
si:ch211-157c3.4
si:ch211-157c3.4
chr22_-_26484268 1.11 ENSDART00000110293
zgc:194551
zgc:194551
chr8_+_2543525 1.10 ENSDART00000129569
ENSDART00000128227
gle1
GLE1 RNA export mediator homolog (yeast)
chr15_+_40079468 1.08 ENSDART00000154947
ngef
neuronal guanine nucleotide exchange factor
chr5_-_69180587 1.07 ENSDART00000156681
ENSDART00000160753
zgc:171967
zgc:171967
chr19_-_2115040 1.04 ENSDART00000020497
snx13
sorting nexin 13
chr21_-_22117085 1.03 ENSDART00000146673
slc35f2
solute carrier family 35, member F2
chr16_+_10557504 1.01 ENSDART00000091241
si:ch73-22o12.1
si:ch73-22o12.1
chr3_+_24094581 0.99 ENSDART00000138270
ENSDART00000131509
copz2
coatomer protein complex, subunit zeta 2
chr1_-_53407448 0.95 ENSDART00000160033
ENSDART00000172322
elmod2
ELMO/CED-12 domain containing 2
chr3_+_25907266 0.94 ENSDART00000170324
ENSDART00000192633
tom1
target of myb1 membrane trafficking protein
chr5_-_69180227 0.92 ENSDART00000154816
zgc:171967
zgc:171967
chr6_-_33924883 0.92 ENSDART00000132762
ENSDART00000148142
ENSDART00000142213
akr1a1b
aldo-keto reductase family 1, member A1b (aldehyde reductase)
chr23_+_25291891 0.92 ENSDART00000016248
pa2g4b
proliferation-associated 2G4, b
chr7_-_59515569 0.92 ENSDART00000163343
ENSDART00000165457
ENSDART00000163745
slx1b
SLX1 homolog B, structure-specific endonuclease subunit
chr3_+_46764278 0.91 ENSDART00000136051
ENSDART00000164930
prkcsh
protein kinase C substrate 80K-H
chr8_+_50150834 0.91 ENSDART00000056074
entpd4
ectonucleoside triphosphate diphosphohydrolase 4
chr19_-_24136233 0.88 ENSDART00000143365
thap7
THAP domain containing 7
chr10_-_1961930 0.87 ENSDART00000122446
tdgf1
teratocarcinoma-derived growth factor 1
chr24_+_19518303 0.86 ENSDART00000027022
ENSDART00000056080
sulf1
sulfatase 1
chr18_+_6641542 0.85 ENSDART00000160379
c2cd5
C2 calcium-dependent domain containing 5
chr20_+_23742574 0.82 ENSDART00000050559
sh3rf1
SH3 domain containing ring finger 1
chr10_-_1961576 0.82 ENSDART00000042441
tdgf1
teratocarcinoma-derived growth factor 1
chr22_-_26289549 0.80 ENSDART00000043774
sde2
SDE2 telomere maintenance homolog (S. pombe)
chr2_+_51783120 0.79 ENSDART00000177559
crygn1
crystallin, gamma N1
chr7_-_41881177 0.79 ENSDART00000174258
ENSDART00000018972
zgc:92818
zgc:92818
chr15_+_23657051 0.78 ENSDART00000078336
klc3
kinesin light chain 3
chr11_+_25583950 0.75 ENSDART00000111961
ccdc120
coiled-coil domain containing 120
chr3_+_35608385 0.74 ENSDART00000193219
ENSDART00000132703
traf7
TNF receptor-associated factor 7
chr18_+_45862414 0.73 ENSDART00000024615
rnpepl1
arginyl aminopeptidase like 1
chr8_+_54263946 0.71 ENSDART00000193119
TMCC1 (1 of many)
transmembrane and coiled-coil domain family 1
chr17_-_8656155 0.68 ENSDART00000148990
ctbp2a
C-terminal binding protein 2a
chr10_-_26218354 0.68 ENSDART00000180764
arfip2b
ADP-ribosylation factor interacting protein 2b
chr5_+_31791001 0.68 ENSDART00000043010
slc25a25b
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25b
chr16_+_52999778 0.66 ENSDART00000011506
nkd2a
naked cuticle homolog 2a
chr7_-_31921687 0.65 ENSDART00000146720
lin7c
lin-7 homolog C (C. elegans)
chr23_+_39854566 0.64 ENSDART00000190423
ENSDART00000164473
ENSDART00000161881
si:ch73-217b7.1
si:ch73-217b7.1
chr15_+_23947932 0.64 ENSDART00000153951
myo18ab
myosin XVIIIAb
chr8_-_5850472 0.63 ENSDART00000179217
CABZ01102147.1

chr9_+_18829360 0.61 ENSDART00000006514
gtf2f2b
general transcription factor IIF, polypeptide 2b
chr5_-_30074332 0.61 ENSDART00000147963
bco2a
beta-carotene oxygenase 2a
chr8_+_2656231 0.61 ENSDART00000160833
fam102aa
family with sequence similarity 102, member Aa
chr5_+_4016271 0.61 ENSDART00000113627
ENSDART00000105832
ENSDART00000121415
ggnbp2
gametogenetin binding protein 2
chr11_+_31680513 0.60 ENSDART00000139900
ENSDART00000040305
diaph3
diaphanous-related formin 3
chr3_+_16841942 0.58 ENSDART00000023985
ENSDART00000145317
stk17al
serine/threonine kinase 17a like
chr17_-_8592824 0.58 ENSDART00000127022
CU462878.1

chr2_-_4032732 0.57 ENSDART00000158335
rab18b
RAB18B, member RAS oncogene family
chr3_-_49138004 0.57 ENSDART00000167173
gipc1
GIPC PDZ domain containing family, member 1
chr20_+_6533260 0.56 ENSDART00000135005
ENSDART00000166356
si:ch211-191a24.4
si:ch211-191a24.4
chr1_-_30762264 0.56 ENSDART00000085454
dis3
DIS3 exosome endoribonuclease and 3'-5' exoribonuclease
chr8_+_25959940 0.56 ENSDART00000143011
ENSDART00000140626
si:dkey-72l14.4
si:dkey-72l14.4
chr11_-_6868474 0.56 ENSDART00000168372
lsm4
LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated
chr13_+_1015749 0.53 ENSDART00000190982
prokr1b
prokineticin receptor 1b
chr20_+_34671386 0.52 ENSDART00000152836
ENSDART00000138226
elp3
elongator acetyltransferase complex subunit 3
chr13_-_35527697 0.52 ENSDART00000016793
memo1
mediator of cell motility 1
chr16_+_23403602 0.52 ENSDART00000159848
s100w
S100 calcium binding protein W
chr16_-_48428035 0.51 ENSDART00000190554
rad21a
RAD21 cohesin complex component a
chr25_-_34740627 0.50 ENSDART00000137665
frs2b
fibroblast growth factor receptor substrate 2b
chr16_+_23404170 0.50 ENSDART00000170061
s100w
S100 calcium binding protein W
chr17_+_50701748 0.49 ENSDART00000191938
ENSDART00000183220
ENSDART00000049464
fermt2
fermitin family member 2
chr13_-_14269626 0.49 ENSDART00000079176
gfra4a
GDNF family receptor alpha 4a
chr12_+_19138452 0.49 ENSDART00000141346
ENSDART00000066397
phf5a
PHD finger protein 5A
chr16_+_25285998 0.48 ENSDART00000154112
si:dkey-29h14.10
si:dkey-29h14.10
chr3_-_5644028 0.48 ENSDART00000019957
ddx39ab
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39Ab
chr11_-_11336986 0.48 ENSDART00000016677
zgc:77929
zgc:77929
chr25_-_37084032 0.47 ENSDART00000025494
hprt1l
hypoxanthine phosphoribosyltransferase 1, like
chr19_+_3215466 0.47 ENSDART00000181288
zgc:86598
zgc:86598
chr23_+_39963599 0.47 ENSDART00000166539
fyco1a
FYVE and coiled-coil domain containing 1a
chr11_-_6868287 0.47 ENSDART00000037824
lsm4
LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated
chr20_+_9128829 0.47 ENSDART00000064144
ENSDART00000137450
bpnt1
bisphosphate nucleotidase 1
chr7_-_34448076 0.46 ENSDART00000170935
nr1h3
nuclear receptor subfamily 1, group H, member 3
chr23_-_37085547 0.46 ENSDART00000144333
ints11
integrator complex subunit 11
chr25_-_31763897 0.45 ENSDART00000041740
ubl7a
ubiquitin-like 7a (bone marrow stromal cell-derived)
chr4_-_14470071 0.45 ENSDART00000143773
plxnb2a
plexin b2a
chr8_+_23355484 0.44 ENSDART00000085361
ENSDART00000125729
dnmt3ba
DNA (cytosine-5-)-methyltransferase 3 beta, duplicate a
chr1_-_29761086 0.44 ENSDART00000136760
alg11
asparagine-linked glycosylation 11 (alpha-1,2-mannosyltransferase)
chr8_+_36560019 0.43 ENSDART00000136418
ENSDART00000061378
ENSDART00000185237
sf3a1
splicing factor 3a, subunit 1
chr4_+_62431132 0.43 ENSDART00000160226
si:ch211-79g12.1
si:ch211-79g12.1
chr23_-_37085959 0.43 ENSDART00000139662
ENSDART00000031016
ints11
integrator complex subunit 11
chr4_-_73587205 0.43 ENSDART00000150837
znf1015
zinc finger protein 1015
chr22_+_25256801 0.42 ENSDART00000193059
BX950205.6

chr25_-_17590971 0.42 ENSDART00000189942
mmp15a
matrix metallopeptidase 15a
chr2_+_47489679 0.42 ENSDART00000074968
acsl3b
acyl-CoA synthetase long chain family member 3b
chr3_-_58165254 0.41 ENSDART00000093031
snu13a
SNU13 homolog, small nuclear ribonucleoprotein a (U4/U6.U5)
chr14_+_2487672 0.40 ENSDART00000170629
ENSDART00000123063
fgf18a
fibroblast growth factor 18a
chr20_-_28931901 0.40 ENSDART00000153082
ENSDART00000046042
susd6
sushi domain containing 6
chr6_+_40832635 0.40 ENSDART00000011931
ruvbl1
RuvB-like AAA ATPase 1
chr18_-_42071876 0.38 ENSDART00000193288
ENSDART00000189021
ENSDART00000019245
arhgap42b
Rho GTPase activating protein 42b
chr17_-_50010121 0.38 ENSDART00000122747
tmem30aa
transmembrane protein 30Aa
chr9_-_12574473 0.37 ENSDART00000191372
ENSDART00000193667
igf2bp2a
insulin-like growth factor 2 mRNA binding protein 2a
chr10_-_25028527 0.37 ENSDART00000040733
cd209
CD209 molecule
chr6_+_46481024 0.36 ENSDART00000155596
si:dkey-7k24.5
si:dkey-7k24.5
chr7_-_26049282 0.36 ENSDART00000136389
ENSDART00000101124
rnaseka
ribonuclease, RNase K a
chr16_+_52343905 0.34 ENSDART00000131051
ifnlr1
interferon lambda receptor 1
chr22_+_25582707 0.34 ENSDART00000184440
aars2
alanyl-tRNA synthetase 2, mitochondrial (putative)
chr15_-_47115787 0.34 ENSDART00000192601
CABZ01079081.1

chr18_-_38245062 0.34 ENSDART00000189092
nat10
N-acetyltransferase 10
chr7_+_26049818 0.33 ENSDART00000173611
si:dkey-6n21.12
si:dkey-6n21.12
chr7_-_12789251 0.32 ENSDART00000052750
adamtsl3
ADAMTS-like 3
chr24_-_38079261 0.32 ENSDART00000105662
crp1
C-reactive protein 1
chr16_-_16152199 0.32 ENSDART00000012718
fabp11b
fatty acid binding protein 11b
chr16_-_20932896 0.31 ENSDART00000180646
tax1bp1b
Tax1 (human T-cell leukemia virus type I) binding protein 1b
chr16_-_21692024 0.31 ENSDART00000123597
si:ch211-154o6.2
si:ch211-154o6.2
chr9_-_54981471 0.30 ENSDART00000097318
fancb
Fanconi anemia, complementation group B
chr2_-_31686353 0.30 ENSDART00000126177
ENSDART00000056679
e2f5
E2F transcription factor 5
chr16_-_40043322 0.27 ENSDART00000145278
si:dkey-29b11.3
si:dkey-29b11.3
chr20_-_18736281 0.27 ENSDART00000142837
enpp5
ectonucleotide pyrophosphatase/phosphodiesterase 5
chr4_-_73756673 0.27 ENSDART00000174274
ENSDART00000192913
ENSDART00000113546
BX855614.4
si:dkey-262g12.14
zgc:171551

si:dkey-262g12.14
zgc:171551
chr14_+_15430991 0.26 ENSDART00000158221
si:dkey-203a12.5
si:dkey-203a12.5
chr22_-_8509215 0.26 ENSDART00000140146
si:ch73-27e22.3
si:ch73-27e22.3
chr9_+_38967248 0.26 ENSDART00000112298
map2
microtubule-associated protein 2
chr4_-_43185261 0.24 ENSDART00000150380
si:dkey-16p6.2
si:dkey-16p6.2
chr22_-_16154771 0.23 ENSDART00000009464
slc30a7
solute carrier family 30 (zinc transporter), member 7
chr7_-_17780048 0.22 ENSDART00000183336
si:dkey-106g10.7
si:dkey-106g10.7
chr12_+_25640480 0.22 ENSDART00000105608
prkcea
protein kinase C, epsilon a
chr22_-_12726556 0.22 ENSDART00000105776
fam207a
family with sequence similarity 207, member A
chr6_-_59381391 0.21 ENSDART00000157066
ppp1r16b
protein phosphatase 1, regulatory subunit 16B
chr23_-_7797207 0.21 ENSDART00000181611
myt1b
myelin transcription factor 1b
chr25_-_27722614 0.21 ENSDART00000190154
zgc:153935
zgc:153935
chr7_-_72208248 0.21 ENSDART00000108916
zmp:0000001168
zmp:0000001168
chr19_+_43715911 0.21 ENSDART00000006344
cap1
CAP, adenylate cyclase-associated protein 1 (yeast)
chr10_-_17550239 0.21 ENSDART00000057513
ska1
spindle and kinetochore associated complex subunit 1
chr18_+_48758916 0.20 ENSDART00000060098
gemin7
gem (nuclear organelle) associated protein 7
chr19_+_42694211 0.18 ENSDART00000180153
clasp2
cytoplasmic linker associated protein 2
chr6_+_45347219 0.18 ENSDART00000188240
LO017951.1

chr3_+_14157090 0.18 ENSDART00000156766
si:ch211-108d22.2
si:ch211-108d22.2
chr3_+_3610140 0.17 ENSDART00000104977
pick1
protein interacting with prkca 1
chr10_+_6013076 0.17 ENSDART00000167613
ENSDART00000159216
hmgcs1
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chr11_+_14287427 0.17 ENSDART00000180903
si:ch211-262i1.3
si:ch211-262i1.3
chr7_-_66864756 0.17 ENSDART00000184462
ENSDART00000189424
ampd3a
adenosine monophosphate deaminase 3a
chr25_-_12923482 0.17 ENSDART00000161754
CR450808.1

chr16_-_35415004 0.16 ENSDART00000170401
ENSDART00000157832
ENSDART00000170048
taf12
TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr19_-_9760994 0.16 ENSDART00000139727
si:dkey-14o18.2
si:dkey-14o18.2
chr1_+_8110562 0.16 ENSDART00000112160
SLC5A10
si:dkeyp-9d4.5
chr3_+_48561112 0.15 ENSDART00000159682
slc16a5b
solute carrier family 16 (monocarboxylate transporter), member 5b
chr1_+_41690402 0.15 ENSDART00000177298
fbxo41
F-box protein 41
chr17_-_25737452 0.15 ENSDART00000152021
si:ch211-214p16.3
si:ch211-214p16.3
chr21_-_43428040 0.14 ENSDART00000148325
stk26
serine/threonine protein kinase 26
chr9_-_22076368 0.14 ENSDART00000128486
crygm2a
crystallin, gamma M2a
chr8_+_23391263 0.14 ENSDART00000149687
si:dkey-16n15.6
si:dkey-16n15.6
chr20_-_34754617 0.13 ENSDART00000148066
znf395b
zinc finger protein 395b
chr14_+_26796684 0.13 ENSDART00000187414
klhl4
kelch-like family member 4
chr18_+_33353755 0.13 ENSDART00000144160
v2rh13
vomeronasal 2 receptor, h13
chr4_+_33012407 0.13 ENSDART00000151873
si:dkey-26h11.2
si:dkey-26h11.2
chr11_-_27702778 0.12 ENSDART00000045942
ENSDART00000125352
phf2
PHD finger protein 2
chr14_-_17072736 0.12 ENSDART00000106333
phox2bb
paired-like homeobox 2bb
chr17_+_4578552 0.12 ENSDART00000038730
ENSDART00000182146
zmp:0000000619
zmp:0000000619
chr14_+_1124409 0.12 ENSDART00000190043
ENSDART00000106708
ENSDART00000160246
sec24b
SEC24 homolog B, COPII coat complex component
chr1_+_8111009 0.12 ENSDART00000152192
SLC5A10
si:dkeyp-9d4.5
chr4_+_67994238 0.12 ENSDART00000160968
si:ch211-133h13.1
si:ch211-133h13.1
chr8_+_6954984 0.12 ENSDART00000145610
si:ch211-255g12.6
si:ch211-255g12.6
chr7_+_8456999 0.12 ENSDART00000172880
jac4
jacalin 4
chr4_-_71554068 0.11 ENSDART00000167414
si:dkey-27n6.1
si:dkey-27n6.1
chr19_+_2631565 0.11 ENSDART00000171487
fam126a
family with sequence similarity 126, member A
chr4_+_58667348 0.11 ENSDART00000186596
ENSDART00000180673
CR388148.2

chr17_+_51499789 0.11 ENSDART00000187701
CABZ01067581.1

chr21_-_3770636 0.11 ENSDART00000053596
scamp1
secretory carrier membrane protein 1
chr4_+_36616118 0.11 ENSDART00000160058
ENSDART00000170506
si:dkey-151g22.1
si:dkey-151g22.1
chr4_+_69375564 0.10 ENSDART00000150334
si:dkey-246j6.1
si:dkey-246j6.1
chr5_+_20148671 0.10 ENSDART00000143205
svopa
SV2 related protein a
chr4_+_58661331 0.10 ENSDART00000188763
CR388148.2

chr4_-_38829098 0.10 ENSDART00000151932
si:dkey-59l11.10
si:dkey-59l11.10
chr12_-_30777540 0.10 ENSDART00000126466
entpd1
ectonucleoside triphosphate diphosphohydrolase 1
chr23_-_31266586 0.10 ENSDART00000139746
si:dkey-261l7.2
si:dkey-261l7.2
chr4_+_71014655 0.10 ENSDART00000170837
si:dkeyp-80d11.14
si:dkeyp-80d11.14
chr4_-_4387012 0.10 ENSDART00000191836
CU468826.3
Danio rerio U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 1-like (LOC100331497), mRNA.
chr4_+_43245188 0.10 ENSDART00000150310
si:dkey-29j8.1
si:dkey-29j8.1
chr1_+_45217425 0.10 ENSDART00000179983
ENSDART00000074683
EVI5L
si:ch211-239f4.1
chr4_+_51201875 0.09 ENSDART00000189875
ENSDART00000186722
BX005380.1

chr4_-_34776147 0.09 ENSDART00000167498
si:dkey-146m20.14
si:dkey-146m20.14
chr14_+_31751260 0.09 ENSDART00000169796
si:dkeyp-11e3.1
si:dkeyp-11e3.1
chr4_+_45388995 0.09 ENSDART00000150802
si:dkey-16p6.1
si:dkey-16p6.1
chr4_-_71416263 0.09 ENSDART00000159812
si:ch211-76m11.15
si:ch211-76m11.15
chr1_+_26626824 0.09 ENSDART00000158193
coro2a
coronin, actin binding protein, 2A
chr13_+_23176330 0.09 ENSDART00000168351
sorbs1
sorbin and SH3 domain containing 1
chr8_-_25338709 0.09 ENSDART00000131616
atp5pb
ATP synthase peripheral stalk-membrane subunit b
chr4_-_33763221 0.09 ENSDART00000132613
ENSDART00000191816
ENSDART00000188473
si:ch211-197f20.1
si:ch211-197f20.1
chr9_-_3519253 0.09 ENSDART00000169586
dcaf17
ddb1 and cul4 associated factor 17

Network of associatons between targets according to the STRING database.

First level regulatory network of otx5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0090008 hypoblast development(GO:0090008)
0.4 2.7 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.4 1.2 GO:1903441 receptor localization to nonmotile primary cilium(GO:0097500) protein localization to ciliary membrane(GO:1903441)
0.3 0.9 GO:0046048 ribonucleoside diphosphate catabolic process(GO:0009191) pyrimidine ribonucleoside diphosphate metabolic process(GO:0009193) UDP metabolic process(GO:0046048)
0.2 1.2 GO:0031053 primary miRNA processing(GO:0031053)
0.2 3.7 GO:0008354 germ cell migration(GO:0008354)
0.2 0.5 GO:0010664 negative regulation of muscle cell apoptotic process(GO:0010656) muscle cell apoptotic process(GO:0010657) striated muscle cell apoptotic process(GO:0010658) regulation of muscle cell apoptotic process(GO:0010660) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664)
0.2 0.5 GO:0002926 tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridine biosynthesis.(GO:0002926)
0.2 0.8 GO:0010828 positive regulation of glucose transport(GO:0010828)
0.2 0.8 GO:0036037 CD8-positive, alpha-beta T cell activation(GO:0036037)
0.2 0.5 GO:0046099 guanine salvage(GO:0006178) GMP salvage(GO:0032263) guanine biosynthetic process(GO:0046099)
0.2 1.1 GO:0014009 glial cell proliferation(GO:0014009)
0.2 0.5 GO:1904729 regulation of intestinal absorption(GO:1904478) regulation of intestinal lipid absorption(GO:1904729)
0.1 0.6 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.1 0.3 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.1 0.9 GO:0021910 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910) regulation of myotome development(GO:2000290)
0.1 0.5 GO:0003173 ventriculo bulbo valve development(GO:0003173)
0.1 0.7 GO:0070073 clustering of voltage-gated calcium channels(GO:0070073)
0.1 0.5 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.1 0.6 GO:0034389 lipid particle organization(GO:0034389)
0.1 0.6 GO:0046247 carotene metabolic process(GO:0016119) carotene catabolic process(GO:0016121) terpene metabolic process(GO:0042214) terpene catabolic process(GO:0046247)
0.1 0.4 GO:0035332 positive regulation of hippo signaling(GO:0035332)
0.1 0.2 GO:1902767 farnesyl diphosphate biosynthetic process, mevalonate pathway(GO:0010142) isoprenoid biosynthetic process via mevalonate(GO:1902767)
0.1 0.6 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
0.1 1.0 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.1 0.4 GO:0000492 box C/D snoRNP assembly(GO:0000492) regulation of heart growth(GO:0060420)
0.1 0.2 GO:0003322 pancreatic A cell development(GO:0003322)
0.1 0.3 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.5 GO:0030431 sleep(GO:0030431)
0.0 0.1 GO:0061188 regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188)
0.0 0.9 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.7 GO:0060061 Spemann organizer formation(GO:0060061)
0.0 1.3 GO:0030038 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.0 0.9 GO:0016180 snRNA processing(GO:0016180)
0.0 1.2 GO:0038202 TORC1 signaling(GO:0038202)
0.0 1.2 GO:0051209 release of sequestered calcium ion into cytosol(GO:0051209)
0.0 0.6 GO:0016075 rRNA catabolic process(GO:0016075)
0.0 0.6 GO:0032418 lysosome localization(GO:0032418)
0.0 0.1 GO:0061549 sympathetic ganglion development(GO:0061549)
0.0 0.7 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.0 1.0 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 1.1 GO:0060415 muscle tissue morphogenesis(GO:0060415)
0.0 1.0 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.4 GO:0006490 oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.0 0.1 GO:2000009 regulation of protein localization to cell surface(GO:2000008) negative regulation of protein localization to cell surface(GO:2000009)
0.0 0.5 GO:0071545 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855) inositol phosphate catabolic process(GO:0071545)
0.0 1.0 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 0.5 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.8 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 0.2 GO:0030816 activation of adenylate cyclase activity(GO:0007190) positive regulation of cAMP metabolic process(GO:0030816) positive regulation of cAMP biosynthetic process(GO:0030819) positive regulation of adenylate cyclase activity(GO:0045762)
0.0 0.1 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.0 0.4 GO:0006305 DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.0 3.5 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.0 0.1 GO:0014743 regulation of muscle hypertrophy(GO:0014743)
0.0 0.9 GO:0006414 translational elongation(GO:0006414)
0.0 0.5 GO:0060972 left/right pattern formation(GO:0060972)
0.0 0.1 GO:0033986 response to methanol(GO:0033986) cellular response to methanol(GO:0071405)
0.0 3.0 GO:0016197 endosomal transport(GO:0016197)
0.0 0.4 GO:0044243 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.0 0.8 GO:0051607 defense response to virus(GO:0051607)
0.0 0.4 GO:0034204 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.0 0.4 GO:0001676 long-chain fatty acid metabolic process(GO:0001676) long-chain fatty-acyl-CoA metabolic process(GO:0035336)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0017177 glucosidase II complex(GO:0017177)
0.2 0.2 GO:0034719 SMN-Sm protein complex(GO:0034719)
0.2 0.6 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.2 0.9 GO:0033557 Slx1-Slx4 complex(GO:0033557)
0.1 1.2 GO:0031931 TORC1 complex(GO:0031931)
0.1 1.0 GO:0005688 U6 snRNP(GO:0005688)
0.1 1.3 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.1 0.4 GO:0097255 R2TP complex(GO:0097255)
0.1 0.6 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.1 1.0 GO:0030126 COPI vesicle coat(GO:0030126)
0.1 0.5 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 0.5 GO:0000798 nuclear cohesin complex(GO:0000798) mitotic cohesin complex(GO:0030892) nuclear mitotic cohesin complex(GO:0034990) nuclear meiotic cohesin complex(GO:0034991)
0.1 0.4 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.1 1.2 GO:0030667 secretory granule membrane(GO:0030667)
0.1 0.5 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 0.6 GO:0000176 nuclear exosome (RNase complex)(GO:0000176) cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 1.0 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.2 GO:0046695 SLIK (SAGA-like) complex(GO:0046695)
0.0 0.9 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.5 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.7 GO:0060170 ciliary membrane(GO:0060170)
0.0 0.3 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.2 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 1.0 GO:0005811 lipid particle(GO:0005811)
0.0 1.1 GO:0005643 nuclear pore(GO:0005643)
0.0 0.2 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.8 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.4 1.1 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.2 0.9 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.2 0.9 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.2 0.6 GO:0097016 L27 domain binding(GO:0097016)
0.2 0.5 GO:0004422 hypoxanthine phosphoribosyltransferase activity(GO:0004422)
0.1 0.4 GO:0004377 GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity(GO:0004377)
0.1 2.7 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 1.7 GO:0070697 activin receptor binding(GO:0070697)
0.1 1.0 GO:0017070 U6 snRNA binding(GO:0017070)
0.1 3.4 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 0.3 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.1 1.2 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1 0.8 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.1 0.4 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.1 0.2 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 0.6 GO:0010436 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.1 1.0 GO:0004382 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.1 0.2 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.1 0.2 GO:0017020 myosin phosphatase regulator activity(GO:0017020)
0.1 0.4 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.1 0.9 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 1.0 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.4 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.5 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.0 0.7 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.9 GO:0000049 tRNA binding(GO:0000049)
0.0 0.5 GO:0008252 nucleotidase activity(GO:0008252)
0.0 0.9 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.6 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 1.2 GO:0030674 protein binding, bridging(GO:0030674)
0.0 0.0 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.0 0.6 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.1 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.4 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0 0.7 GO:0005347 ATP transmembrane transporter activity(GO:0005347)
0.0 0.9 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.9 GO:0030276 clathrin binding(GO:0030276)
0.0 0.2 GO:0017025 TBP-class protein binding(GO:0017025)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 1.2 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 1.4 PID GLYPICAN 1PATHWAY Glypican 1 network
0.1 1.1 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 1.3 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.6 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 1.4 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.5 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.5 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.6 PID MYC PATHWAY C-MYC pathway
0.0 0.3 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.6 PID CDC42 PATHWAY CDC42 signaling events
0.0 0.9 PID CMYB PATHWAY C-MYB transcription factor network
0.0 1.2 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.7 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.2 1.2 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 1.2 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.1 0.5 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 0.9 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.1 1.0 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1 1.3 REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION Genes involved in Nuclear Events (kinase and transcription factor activation)
0.1 0.6 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 1.2 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.8 REACTOME KINESINS Genes involved in Kinesins
0.0 0.5 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 1.1 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.4 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.2 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.3 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.3 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.3 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.2 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.4 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.5 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway