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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for patz1

Z-value: 1.49

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Transcription factors associated with patz1

Gene Symbol Gene ID Gene Info
patz1
ENSDARG00000076584 POZ/BTB and AT hook containing zinc finger 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
patz1dr11_v1_chr6_+_40951227_40951227-0.948.3e-09Click!

Activity profile of patz1 motif

Sorted Z-values of patz1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr19_+_48111285 5.85 ENSDART00000169420
nme2b.2
NME/NM23 nucleoside diphosphate kinase 2b, tandem duplicate 2
chr6_+_475264 5.61 ENSDART00000193615
LO017974.1

chr20_-_147574 5.12 ENSDART00000104762
ENSDART00000131635
slc16a10
solute carrier family 16 (aromatic amino acid transporter), member 10
chr3_+_12554801 5.03 ENSDART00000167177
ccnf
cyclin F
chr20_-_7080427 4.90 ENSDART00000140166
ENSDART00000023677
si:ch211-121a2.2
si:ch211-121a2.2
chr6_-_42418225 4.64 ENSDART00000002501
ip6k2a
inositol hexakisphosphate kinase 2a
chr21_+_11885404 4.29 ENSDART00000092015
dcaf12
DDB1 and CUL4 associated factor 12
chr3_+_62126981 4.26 ENSDART00000060527
drc3
dynein regulatory complex subunit 3
chr7_+_34688527 4.23 ENSDART00000108473
plekhg4
pleckstrin homology domain containing, family G (with RhoGef domain) member 4
chr2_-_44183613 4.02 ENSDART00000079596
cadm3
cell adhesion molecule 3
chr7_+_568819 4.00 ENSDART00000173716
nrxn2b
neurexin 2b
chr16_+_10918252 3.87 ENSDART00000172949
pou2f2a
POU class 2 homeobox 2a
chr2_-_44183451 3.73 ENSDART00000111246
cadm3
cell adhesion molecule 3
chr9_-_24413008 3.68 ENSDART00000135897
tmeff2a
transmembrane protein with EGF-like and two follistatin-like domains 2a
chr21_-_308852 3.67 ENSDART00000151613
lhfpl2a
LHFPL tetraspan subfamily member 2a
chr12_-_26851726 3.58 ENSDART00000047724
zeb1b
zinc finger E-box binding homeobox 1b
chr10_-_5857548 3.46 ENSDART00000166933
si:ch211-281k19.2
si:ch211-281k19.2
chr23_+_10347851 3.42 ENSDART00000127667
krt18
keratin 18
chr7_+_529522 3.42 ENSDART00000190811
nrxn2b
neurexin 2b
chr6_+_7249531 3.38 ENSDART00000125912
ENSDART00000083424
ENSDART00000049695
ENSDART00000136088
dzip1
DAZ interacting zinc finger protein 1
chr25_-_5189989 3.35 ENSDART00000097520
shisal1b
shisa like 1b
chr13_+_12045758 3.33 ENSDART00000079398
ENSDART00000165467
ENSDART00000165880
gng2
guanine nucleotide binding protein (G protein), gamma 2
chr20_-_48516765 3.30 ENSDART00000150200
si:zfos-223e1.2
si:zfos-223e1.2
chr21_-_37733571 3.19 ENSDART00000176214
mpp1
membrane protein, palmitoylated 1
chr3_+_60007703 3.15 ENSDART00000157351
ENSDART00000153928
ENSDART00000155876
si:ch211-110e21.3
si:ch211-110e21.3
chr22_-_1245226 3.12 ENSDART00000161292
ampd2a
adenosine monophosphate deaminase 2a
chr7_+_73630751 3.03 ENSDART00000159745
PCP4L1
si:dkey-46i9.1
chr5_-_68022631 2.89 ENSDART00000143199
wasf3a
WAS protein family, member 3a
chr10_-_641609 2.74 ENSDART00000041236
rfx3
regulatory factor X, 3 (influences HLA class II expression)
chr3_-_32180796 2.69 ENSDART00000133191
ENSDART00000055308
pih1d1
PIH1 domain containing 1
chr12_+_31616412 2.67 ENSDART00000124439
cpn1
carboxypeptidase N, polypeptide 1
chr6_+_9241121 2.62 ENSDART00000064989
pimr70
Pim proto-oncogene, serine/threonine kinase, related 70
chr25_+_5035343 2.60 ENSDART00000011751
parvb
parvin, beta
chr3_-_16289826 2.55 ENSDART00000131972
bckdhbl
branched chain keto acid dehydrogenase E1, beta polypeptide, like
chr17_+_43889371 2.51 ENSDART00000156871
ENSDART00000154702
msh4
mutS homolog 4
chr17_-_4395373 2.50 ENSDART00000015923
klhl10a
kelch-like family member 10a
chr6_-_59942335 2.47 ENSDART00000168416
fbxl3b
F-box and leucine-rich repeat protein 3b
chr13_+_33304187 2.43 ENSDART00000075826
ENSDART00000145295
dcdc2b
doublecortin domain containing 2B
chr10_-_27197044 2.42 ENSDART00000137928
auts2a
autism susceptibility candidate 2a
chr4_+_57093908 2.38 ENSDART00000170198
si:ch211-238e22.5
si:ch211-238e22.5
chr16_+_4838808 2.38 ENSDART00000179363
ibtk
inhibitor of Bruton agammaglobulinemia tyrosine kinase
chr6_-_9922266 2.34 ENSDART00000151549
pimr73
Pim proto-oncogene, serine/threonine kinase, related 73
chr7_-_18168493 2.33 ENSDART00000127428
peli3
pellino E3 ubiquitin protein ligase family member 3
chr19_+_31904836 2.31 ENSDART00000162297
ENSDART00000088340
ENSDART00000151280
ENSDART00000151218
tpd52
tumor protein D52
chr25_+_16356083 2.31 ENSDART00000125925
ENSDART00000125444
tead1a
TEA domain family member 1a
chr1_-_38709551 2.29 ENSDART00000128794
gpm6ab
glycoprotein M6Ab
chr5_-_10002260 2.28 ENSDART00000141831
si:ch73-266o15.4
si:ch73-266o15.4
chr2_+_33052360 2.28 ENSDART00000134651
rnf220a
ring finger protein 220a
chr13_+_41022502 2.20 ENSDART00000026808
dkk1a
dickkopf WNT signaling pathway inhibitor 1a
chr21_+_7823146 2.20 ENSDART00000030579
crhbp
corticotropin releasing hormone binding protein
chr1_-_58562129 2.16 ENSDART00000159070
slc27a1b
solute carrier family 27 (fatty acid transporter), member 1b
chr15_-_47956388 2.15 ENSDART00000116506
si:ch1073-111c8.3
si:ch1073-111c8.3
chr1_-_669717 2.13 ENSDART00000160564
cyyr1
cysteine/tyrosine-rich 1
chr19_+_233143 2.13 ENSDART00000175273
syngap1a
synaptic Ras GTPase activating protein 1a
chr21_-_5056812 2.12 ENSDART00000139713
ENSDART00000140859
zgc:77838
zgc:77838
chr2_-_1569250 2.11 ENSDART00000167202
dab1b
Dab, reelin signal transducer, homolog 1b (Drosophila)
chr15_-_21837207 2.08 ENSDART00000089953
sik2b
salt-inducible kinase 2b
chr10_+_8629275 2.08 ENSDART00000129643
aplnrb
apelin receptor b
chr6_-_60104628 2.06 ENSDART00000057463
ENSDART00000169188
pmepa1
prostate transmembrane protein, androgen induced 1
chr12_+_33919502 2.05 ENSDART00000085888
trim8b
tripartite motif containing 8b
chr5_-_31875645 2.01 ENSDART00000098160
tmem119b
transmembrane protein 119b
chr22_-_20309283 2.01 ENSDART00000182125
ENSDART00000048775
si:dkey-110c1.10
si:dkey-110c1.10
chr3_+_45687266 2.00 ENSDART00000131652
gpr146
G protein-coupled receptor 146
chr16_-_21785261 1.97 ENSDART00000078858
si:ch73-86n18.1
si:ch73-86n18.1
chr6_+_9893554 1.96 ENSDART00000064979
pimr74
Pim proto-oncogene, serine/threonine kinase, related 74
chr19_-_9522548 1.96 ENSDART00000045245
ing4
inhibitor of growth family, member 4
chr14_-_9522364 1.95 ENSDART00000054689
atoh8
atonal bHLH transcription factor 8
chr21_+_45223194 1.93 ENSDART00000150902
si:ch73-269m14.3
si:ch73-269m14.3
chr2_+_24786765 1.91 ENSDART00000141030
pde4ca
phosphodiesterase 4C, cAMP-specific a
chr15_+_19838458 1.88 ENSDART00000101204
alcamb
activated leukocyte cell adhesion molecule b
chr22_+_24157807 1.87 ENSDART00000159165
b3galt2
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
chr25_+_150570 1.87 ENSDART00000170892
adam10b
ADAM metallopeptidase domain 10b
chr19_-_6873107 1.87 ENSDART00000124440
CABZ01029822.1

chr13_+_21826369 1.86 ENSDART00000165150
ENSDART00000192115
zswim8
zinc finger, SWIM-type containing 8
chr2_-_30693742 1.85 ENSDART00000090292
ctnnd2b
catenin (cadherin-associated protein), delta 2b
chr13_+_21826096 1.85 ENSDART00000056432
zswim8
zinc finger, SWIM-type containing 8
chr3_+_1211242 1.84 ENSDART00000171287
ENSDART00000165769
poldip3
polymerase (DNA-directed), delta interacting protein 3
chr8_+_26034623 1.82 ENSDART00000004521
ENSDART00000142555
arih2
ariadne homolog 2 (Drosophila)
chr16_+_4839078 1.79 ENSDART00000150111
ibtk
inhibitor of Bruton agammaglobulinemia tyrosine kinase
chr1_-_58561963 1.79 ENSDART00000165040
slc27a1b
solute carrier family 27 (fatty acid transporter), member 1b
chr24_+_3050020 1.78 ENSDART00000004241
inhbaa
inhibin, beta Aa
chr1_-_40123943 1.77 ENSDART00000146917
si:ch211-113e8.10
si:ch211-113e8.10
chr10_+_41159241 1.76 ENSDART00000141657
anxa4
annexin A4
chr12_+_2522642 1.75 ENSDART00000152567
frmpd2
FERM and PDZ domain containing 2
chr9_+_34230067 1.74 ENSDART00000139157
nxpe3
neurexophilin and PC-esterase domain family, member 3
chr24_+_42127983 1.71 ENSDART00000190157
ENSDART00000176032
ENSDART00000175790
wwp1
WW domain containing E3 ubiquitin protein ligase 1
chr20_+_20672163 1.70 ENSDART00000027758
rtn1b
reticulon 1b
chr13_-_44738574 1.70 ENSDART00000074761
zfand3
zinc finger, AN1-type domain 3
chr22_+_2860260 1.70 ENSDART00000106221
si:dkey-20i20.2
si:dkey-20i20.2
chr6_-_47840465 1.68 ENSDART00000141986
lrig2
leucine-rich repeats and immunoglobulin-like domains 2
chr7_-_24236364 1.68 ENSDART00000010124
slc7a8a
solute carrier family 7 (amino acid transporter light chain, L system), member 8a
chr16_+_31853919 1.66 ENSDART00000133886
atn1
atrophin 1
chr20_+_11800063 1.64 ENSDART00000152230
si:ch211-155o21.4
si:ch211-155o21.4
chr8_+_27555314 1.63 ENSDART00000135568
ENSDART00000016696
rhocb
ras homolog family member Cb
chr17_-_23446760 1.63 ENSDART00000104715
pcgf5a
polycomb group ring finger 5a
chr3_-_62380146 1.61 ENSDART00000155853
gprc5ba
G protein-coupled receptor, class C, group 5, member Ba
chr1_+_54037077 1.61 ENSDART00000109386
triobpa
TRIO and F-actin binding protein a
chr24_+_42132962 1.61 ENSDART00000187739
wwp1
WW domain containing E3 ubiquitin protein ligase 1
chr14_-_6225336 1.59 ENSDART00000111681
hdx
highly divergent homeobox
chr16_+_11029762 1.59 ENSDART00000091183
erfl3
Ets2 repressor factor like 3
chr8_-_14179798 1.57 ENSDART00000040645
ENSDART00000146749
rhoaa
ras homolog gene family, member Aa
chr23_+_2421689 1.56 ENSDART00000180200
tcp1
t-complex 1
chr13_-_33671694 1.55 ENSDART00000143945
ENSDART00000100504
zgc:163030
zgc:163030
chr24_+_40473032 1.53 ENSDART00000084238
ENSDART00000178508
CABZ01076968.1

chr1_-_44704261 1.53 ENSDART00000133210
si:dkey-28b4.8
si:dkey-28b4.8
chr18_+_44649804 1.52 ENSDART00000059063
ehd2b
EH-domain containing 2b
chr10_-_35410518 1.52 ENSDART00000048430
gabrr3a
gamma-aminobutyric acid (GABA) A receptor, rho 3a
chr20_+_305035 1.50 ENSDART00000104807
si:dkey-119m7.4
si:dkey-119m7.4
chr22_+_508290 1.45 ENSDART00000135403
nuak2
NUAK family, SNF1-like kinase, 2
chr12_-_45349849 1.45 ENSDART00000183036
CABZ01068367.1
Danio rerio uncharacterized LOC100332446 (LOC100332446), mRNA.
chr15_-_21837515 1.42 ENSDART00000185423
sik2b
salt-inducible kinase 2b
chr19_+_4912817 1.42 ENSDART00000101658
ENSDART00000165082
ppp1r1b
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr5_-_52784152 1.42 ENSDART00000169307
fam189a2
family with sequence similarity 189, member A2
chr14_-_33454595 1.42 ENSDART00000109615
ENSDART00000173267
ENSDART00000185737
ENSDART00000190989
tmem255a
transmembrane protein 255A
chr8_+_46010838 1.41 ENSDART00000143126
si:ch211-119d14.2
si:ch211-119d14.2
chr2_+_33052169 1.38 ENSDART00000180008
rnf220a
ring finger protein 220a
chr17_-_36936856 1.37 ENSDART00000010274
ENSDART00000188887
dpysl5a
dihydropyrimidinase-like 5a
chr8_+_2456854 1.37 ENSDART00000133938
ENSDART00000002764
polb
polymerase (DNA directed), beta
chr5_+_37087583 1.35 ENSDART00000049900
tagln2
transgelin 2
chr8_+_10304981 1.34 ENSDART00000160766
pim1
Pim-1 proto-oncogene, serine/threonine kinase
chr23_-_35064785 1.33 ENSDART00000172240
BX294434.1

chr23_+_2421313 1.32 ENSDART00000126038
tcp1
t-complex 1
chr10_-_5844915 1.32 ENSDART00000185929
ankrd55
ankyrin repeat domain 55
chr20_+_535458 1.31 ENSDART00000152453
dse
dermatan sulfate epimerase
chr10_-_27196093 1.30 ENSDART00000185282
auts2a
autism susceptibility candidate 2a
chr17_-_53329704 1.29 ENSDART00000193895
exd1
exonuclease 3'-5' domain containing 1
chr20_+_18741089 1.29 ENSDART00000183218
fam167ab
family with sequence similarity 167, member Ab
chr19_-_24555935 1.27 ENSDART00000132660
ENSDART00000162801
polr3gla
polymerase (RNA) III (DNA directed) polypeptide G like a
chr8_-_20138054 1.26 ENSDART00000133141
ENSDART00000147634
ENSDART00000029939
rfx2
regulatory factor X, 2 (influences HLA class II expression)
chr8_+_8291492 1.26 ENSDART00000151314
srpk3
SRSF protein kinase 3
chr21_+_13861589 1.24 ENSDART00000015629
ENSDART00000171306
stxbp1a
syntaxin binding protein 1a
chr19_+_22216778 1.22 ENSDART00000052521
nfatc1
nuclear factor of activated T cells 1
chr15_-_5742531 1.21 ENSDART00000045985
phkg1a
phosphorylase kinase, gamma 1a (muscle)
chr22_+_35068046 1.20 ENSDART00000161660
ENSDART00000169573
si:ch73-173h19.3
si:ch73-173h19.3
chr11_-_30630628 1.19 ENSDART00000103265
zgc:158773
zgc:158773
chr20_-_51727860 1.18 ENSDART00000147044
brox
BRO1 domain and CAAX motif containing
chr19_+_9533008 1.18 ENSDART00000104607
fam131ba
family with sequence similarity 131, member Ba
chr19_-_5254699 1.18 ENSDART00000081951
stx1b
syntaxin 1B
chr2_-_51700709 1.17 ENSDART00000188601
tgm1l1
transglutaminase 1 like 1
chr2_-_23004286 1.17 ENSDART00000134664
ENSDART00000110373
ENSDART00000185833
ENSDART00000187235
znf414
mllt1b
zinc finger protein 414
MLLT1, super elongation complex subunit b
chr7_-_30217000 1.17 ENSDART00000173646
znf710b
zinc finger protein 710b
chr10_-_1625080 1.17 ENSDART00000137285
nup155
nucleoporin 155
chr13_+_12045475 1.16 ENSDART00000163053
ENSDART00000160812
ENSDART00000158244
gng2
guanine nucleotide binding protein (G protein), gamma 2
chr1_+_54908895 1.16 ENSDART00000145652
golga7ba
golgin A7 family, member Ba
chr16_-_42390441 1.15 ENSDART00000148475
cspg5a
chondroitin sulfate proteoglycan 5a
chr14_+_24283915 1.14 ENSDART00000172868
klhl3
kelch-like family member 3
chr5_+_22969651 1.14 ENSDART00000089992
ENSDART00000145477
hmgn7
high mobility group nucleosomal binding domain 7
chr8_-_12403077 1.12 ENSDART00000142150
phf19
PHD finger protein 19
chr4_-_119689 1.11 ENSDART00000161055
dusp16
dual specificity phosphatase 16
chr13_+_36633355 1.11 ENSDART00000135612
si:ch211-67f24.7
si:ch211-67f24.7
chr17_+_1323699 1.09 ENSDART00000172540
adssl1
adenylosuccinate synthase like 1
chr9_+_13714379 1.09 ENSDART00000017593
ENSDART00000145503
tmem237a
transmembrane protein 237a
chr4_-_8152746 1.07 ENSDART00000012928
ENSDART00000177482
wnk1b
WNK lysine deficient protein kinase 1b
chr3_+_6469754 1.06 ENSDART00000185809
NUP85 (1 of many)
nucleoporin 85
chr8_+_1187928 1.05 ENSDART00000127252
slc35d2
solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2
chr5_-_40510397 1.05 ENSDART00000146237
ENSDART00000051065
fsta
follistatin a
chr9_+_51891 1.04 ENSDART00000163529
zgc:158316
zgc:158316
chr3_-_5964557 1.04 ENSDART00000184738
BX284638.1

chr16_-_20707742 1.03 ENSDART00000103630
creb5b
cAMP responsive element binding protein 5b
chr3_+_16229911 1.03 ENSDART00000121728
rpl19
ribosomal protein L19
chr11_+_25112269 1.02 ENSDART00000147546
ndrg3a
ndrg family member 3a
chr21_-_22325124 1.01 ENSDART00000142100
gdpd4b
glycerophosphodiester phosphodiesterase domain containing 4b
chr11_-_12051805 1.01 ENSDART00000110117
ENSDART00000182744
socs7
suppressor of cytokine signaling 7
chr15_-_47607480 1.00 ENSDART00000171605
socs9
suppressor of cytokine signaling 9
chr24_-_21258945 1.00 ENSDART00000111025
boc
BOC cell adhesion associated, oncogene regulated
chr18_-_50845804 1.00 ENSDART00000158517
PDPR
si:cabz01113374.3
chr21_+_26697536 0.99 ENSDART00000004109
gng3
guanine nucleotide binding protein (G protein), gamma 3
chr2_+_3595333 0.98 ENSDART00000041052
c1ql3b
complement component 1, q subcomponent-like 3b
chr5_+_30699260 0.98 ENSDART00000012888
atp5l
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit g
chr12_+_48841182 0.97 ENSDART00000109315
ENSDART00000185609
ENSDART00000187217
dlg5b.1
discs, large homolog 5b (Drosophila), tandem duplicate 1
chr1_-_12278522 0.97 ENSDART00000142122
ENSDART00000003825
cplx2l
complexin 2, like
chr21_+_28445052 0.96 ENSDART00000077871
pygma
phosphorylase, glycogen, muscle A
chr20_+_18740518 0.95 ENSDART00000142196
fam167ab
family with sequence similarity 167, member Ab
chr13_-_50200042 0.95 ENSDART00000074230
pkz
protein kinase containing Z-DNA binding domains
chr8_+_10305400 0.95 ENSDART00000172400
pim1
Pim-1 proto-oncogene, serine/threonine kinase
chr15_+_1397811 0.94 ENSDART00000102125
schip1
schwannomin interacting protein 1
chr22_+_1006573 0.94 ENSDART00000123458
pparda
peroxisome proliferator-activated receptor delta a
chr10_+_33895315 0.94 ENSDART00000142881
fryb
furry homolog b (Drosophila)
chr5_-_36837846 0.93 ENSDART00000032481
ckma
creatine kinase, muscle a
chr1_-_10647484 0.93 ENSDART00000164541
ENSDART00000188958
ENSDART00000190904
si:dkey-31e10.1
si:dkey-31e10.1
chr13_-_45523026 0.91 ENSDART00000020663
rhd
Rh blood group, D antigen
chr2_+_54389750 0.91 ENSDART00000189236
rab12
RAB12, member RAS oncogene family
chr20_-_5052786 0.91 ENSDART00000138818
ENSDART00000181655
ENSDART00000164274
arid1b
AT rich interactive domain 1B (SWI1-like)
chr16_-_42390640 0.90 ENSDART00000193214
ENSDART00000102305
cspg5a
chondroitin sulfate proteoglycan 5a
chr25_-_37331513 0.89 ENSDART00000111862
ldlrad3
low density lipoprotein receptor class A domain containing 3
chr4_-_2440175 0.89 ENSDART00000058059
OSBPL8
oxysterol binding protein like 8
chr5_-_16351306 0.88 ENSDART00000168643
CABZ01088700.1

chr15_-_2734560 0.88 ENSDART00000153853
ppp5c
protein phosphatase 5, catalytic subunit
chr24_+_37449893 0.88 ENSDART00000164405
nlrc3
NLR family, CARD domain containing 3
chr2_+_38147761 0.88 ENSDART00000135307
sall2
spalt-like transcription factor 2
chr13_-_31647323 0.87 ENSDART00000135381
six4a
SIX homeobox 4a
chr25_+_21324588 0.86 ENSDART00000151842
lrrn3a
leucine rich repeat neuronal 3a
chr13_-_12494575 0.86 ENSDART00000137761
si:dkey-20i10.7
si:dkey-20i10.7
chr5_-_1047222 0.83 ENSDART00000181112
mbd2
methyl-CpG binding domain protein 2
chr19_+_11985572 0.83 ENSDART00000130537
spag1a
sperm associated antigen 1a
chr14_-_962171 0.82 ENSDART00000010773
acsl1b
acyl-CoA synthetase long chain family member 1b
chr10_+_45148167 0.82 ENSDART00000172621
ogdhb
oxoglutarate (alpha-ketoglutarate) dehydrogenase b (lipoamide)
chr5_+_45138934 0.82 ENSDART00000041412
ENSDART00000136002
smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr9_+_48455909 0.81 ENSDART00000167243
lrp2a
low density lipoprotein receptor-related protein 2a
chr11_-_3334248 0.80 ENSDART00000154314
ENSDART00000121861
prph
peripherin

Network of associatons between targets according to the STRING database.

First level regulatory network of patz1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.9 GO:0031649 heat generation(GO:0031649) regulation of heat generation(GO:0031650) positive regulation of heat generation(GO:0031652) regulation of phospholipid biosynthetic process(GO:0071071) negative regulation of phospholipid biosynthetic process(GO:0071072)
0.7 2.2 GO:0090278 negative regulation of peptide secretion(GO:0002792) negative regulation of peptide hormone secretion(GO:0090278)
0.7 3.6 GO:0070587 regulation of cell-cell adhesion involved in gastrulation(GO:0070587)
0.7 2.0 GO:0033690 positive regulation of osteoblast proliferation(GO:0033690)
0.6 1.9 GO:2001014 regulation of skeletal muscle cell differentiation(GO:2001014)
0.6 5.0 GO:0046606 negative regulation of centrosome duplication(GO:0010826) negative regulation of centrosome cycle(GO:0046606)
0.5 2.1 GO:1903587 regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587) positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903589)
0.5 0.5 GO:0060855 venous endothelial cell migration involved in lymph vessel development(GO:0060855)
0.5 2.3 GO:0008592 regulation of Toll signaling pathway(GO:0008592)
0.5 3.2 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.4 3.7 GO:0046546 development of primary male sexual characteristics(GO:0046546)
0.4 1.2 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228) protein localization to nuclear envelope(GO:0090435)
0.4 2.7 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.4 1.1 GO:0072156 distal tubule morphogenesis(GO:0072156)
0.4 6.0 GO:0006228 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.3 4.6 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.3 1.0 GO:0052576 carbohydrate localization(GO:0052575) carbohydrate storage(GO:0052576)
0.3 3.4 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.3 2.1 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.3 3.9 GO:0032264 IMP salvage(GO:0032264)
0.3 1.9 GO:0021885 forebrain cell migration(GO:0021885)
0.3 2.1 GO:0097477 spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
0.3 1.3 GO:0030205 dermatan sulfate metabolic process(GO:0030205)
0.2 1.2 GO:0098881 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.2 2.5 GO:0000710 meiotic mismatch repair(GO:0000710)
0.2 2.0 GO:0099550 trans-synaptic signalling, modulating synaptic transmission(GO:0099550)
0.2 0.8 GO:0070293 renal absorption(GO:0070293)
0.2 1.6 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.2 2.9 GO:2000601 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.2 3.7 GO:0021884 forebrain neuron development(GO:0021884)
0.2 0.5 GO:0019695 choline metabolic process(GO:0019695)
0.2 0.9 GO:0035332 positive regulation of hippo signaling(GO:0035332)
0.2 1.4 GO:0010887 negative regulation of cholesterol storage(GO:0010887)
0.1 1.2 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.1 2.7 GO:0001539 cilium or flagellum-dependent cell motility(GO:0001539) cilium-dependent cell motility(GO:0060285)
0.1 5.0 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.1 1.9 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.1 3.7 GO:0070831 basement membrane assembly(GO:0070831)
0.1 0.5 GO:0070285 pigment cell development(GO:0070285)
0.1 0.8 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.1 1.6 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.1 2.5 GO:0006198 cAMP catabolic process(GO:0006198)
0.1 2.0 GO:1903288 positive regulation of sodium ion transport(GO:0010765) positive regulation of sodium ion transmembrane transport(GO:1902307) regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288) positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.1 0.4 GO:0060945 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171) Schwann cell migration(GO:0036135) cardiac neuron differentiation(GO:0060945) cardiac neuron development(GO:0060959)
0.1 0.6 GO:0003261 cardiac muscle progenitor cell migration to the midline involved in heart field formation(GO:0003261)
0.1 2.3 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.1 0.6 GO:0010799 regulation of peptidyl-threonine phosphorylation(GO:0010799) negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.1 2.5 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.1 0.6 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.1 0.9 GO:0097106 postsynaptic density organization(GO:0097106)
0.1 2.2 GO:1990399 sensory epithelium regeneration(GO:0070654) epithelium regeneration(GO:1990399)
0.1 2.2 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.1 2.3 GO:0030183 B cell differentiation(GO:0030183)
0.1 0.4 GO:0097037 heme export(GO:0097037)
0.1 4.4 GO:0048010 vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.1 1.0 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.1 0.4 GO:0071881 adenylate cyclase-inhibiting adrenergic receptor signaling pathway(GO:0071881)
0.1 2.3 GO:0007634 optokinetic behavior(GO:0007634)
0.1 0.8 GO:1901998 toxin transport(GO:1901998)
0.1 1.8 GO:0030032 lamellipodium assembly(GO:0030032)
0.1 0.8 GO:0048635 negative regulation of muscle organ development(GO:0048635)
0.1 1.0 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.1 1.2 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.1 0.1 GO:0030072 peptide secretion(GO:0002790) regulation of peptide secretion(GO:0002791) peptide hormone secretion(GO:0030072) regulation of peptide transport(GO:0090087) regulation of peptide hormone secretion(GO:0090276)
0.1 1.1 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 0.6 GO:0051013 microtubule severing(GO:0051013)
0.1 0.3 GO:0009886 post-embryonic morphogenesis(GO:0009886) post-embryonic organ development(GO:0048569)
0.1 1.5 GO:0018149 peptide cross-linking(GO:0018149)
0.1 1.9 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.1 0.3 GO:0090230 regulation of centromere complex assembly(GO:0090230) regulation of kinetochore assembly(GO:0090234)
0.1 0.3 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.1 0.9 GO:0006599 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.1 0.6 GO:0042135 neurotransmitter catabolic process(GO:0042135)
0.1 0.5 GO:0002446 neutrophil mediated immunity(GO:0002446)
0.1 1.3 GO:0034587 piRNA metabolic process(GO:0034587)
0.1 1.0 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208)
0.1 0.2 GO:0035751 regulation of lysosomal lumen pH(GO:0035751)
0.1 2.1 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.1 0.2 GO:0043029 T cell homeostasis(GO:0043029) lymphocyte apoptotic process(GO:0070227)
0.1 0.3 GO:0036268 swimming(GO:0036268)
0.1 5.4 GO:0045732 positive regulation of protein catabolic process(GO:0045732)
0.1 0.2 GO:0014814 regulation of synaptic growth at neuromuscular junction(GO:0008582) axon regeneration at neuromuscular junction(GO:0014814) positive regulation of synaptic growth at neuromuscular junction(GO:0045887)
0.1 2.6 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.1 0.4 GO:0061298 retina vasculature development in camera-type eye(GO:0061298)
0.0 2.2 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 1.8 GO:0015804 neutral amino acid transport(GO:0015804)
0.0 0.6 GO:0009435 NAD biosynthetic process(GO:0009435)
0.0 1.4 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.0 1.4 GO:0048886 neuromast hair cell differentiation(GO:0048886)
0.0 1.3 GO:0003323 type B pancreatic cell development(GO:0003323)
0.0 0.6 GO:0050679 positive regulation of epithelial cell proliferation(GO:0050679)
0.0 3.4 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.7 GO:0046549 retinal cone cell development(GO:0046549)
0.0 0.6 GO:0042407 cristae formation(GO:0042407)
0.0 1.3 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 0.4 GO:0042044 fluid transport(GO:0042044)
0.0 0.8 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.0 0.1 GO:0045649 regulation of macrophage differentiation(GO:0045649)
0.0 1.0 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.5 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.2 GO:1990108 protein linear deubiquitination(GO:1990108)
0.0 1.8 GO:0060393 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862) regulation of pathway-restricted SMAD protein phosphorylation(GO:0060393)
0.0 0.4 GO:0042982 amyloid precursor protein metabolic process(GO:0042982)
0.0 1.5 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.3 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.8 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.5 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 0.2 GO:1902259 regulation of delayed rectifier potassium channel activity(GO:1902259)
0.0 0.5 GO:0002574 thrombocyte differentiation(GO:0002574)
0.0 2.3 GO:1902667 regulation of axon guidance(GO:1902667)
0.0 2.7 GO:0070121 Kupffer's vesicle development(GO:0070121)
0.0 0.2 GO:0060832 oocyte animal/vegetal axis specification(GO:0060832)
0.0 0.5 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.2 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.0 0.5 GO:0097178 ruffle organization(GO:0031529) ruffle assembly(GO:0097178)
0.0 0.6 GO:0015671 oxygen transport(GO:0015671)
0.0 0.1 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.0 1.3 GO:0007173 epidermal growth factor receptor signaling pathway(GO:0007173)
0.0 1.2 GO:0009250 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 0.7 GO:0051289 protein homotetramerization(GO:0051289)
0.0 0.8 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 0.1 GO:0036378 calcitriol biosynthetic process from calciol(GO:0036378) vitamin D biosynthetic process(GO:0042368) cellular alcohol metabolic process(GO:0044107) cellular alcohol biosynthetic process(GO:0044108)
0.0 0.2 GO:0030819 activation of adenylate cyclase activity(GO:0007190) positive regulation of cAMP metabolic process(GO:0030816) positive regulation of cAMP biosynthetic process(GO:0030819) positive regulation of adenylate cyclase activity(GO:0045762)
0.0 0.2 GO:0021628 olfactory nerve development(GO:0021553) olfactory nerve morphogenesis(GO:0021627) olfactory nerve formation(GO:0021628)
0.0 9.6 GO:0043066 negative regulation of apoptotic process(GO:0043066)
0.0 1.4 GO:0051607 defense response to virus(GO:0051607)
0.0 0.5 GO:0003171 atrioventricular valve development(GO:0003171)
0.0 2.0 GO:0016573 histone acetylation(GO:0016573)
0.0 0.6 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.0 0.5 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.0 1.0 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.0 0.6 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.6 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.2 GO:0045851 vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452)
0.0 0.3 GO:0032291 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.0 0.2 GO:0031397 negative regulation of protein ubiquitination(GO:0031397)
0.0 0.1 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.0 0.7 GO:0009306 protein secretion(GO:0009306)
0.0 0.6 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 0.5 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:0032656 interleukin-13 production(GO:0032616) regulation of interleukin-13 production(GO:0032656)
0.0 1.1 GO:0060027 convergent extension involved in gastrulation(GO:0060027)
0.0 0.7 GO:0009755 hormone-mediated signaling pathway(GO:0009755)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.7 GO:0097255 R2TP complex(GO:0097255)
0.4 2.3 GO:0070062 extracellular exosome(GO:0070062)
0.3 5.5 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.3 1.2 GO:0044611 nuclear pore inner ring(GO:0044611)
0.3 2.9 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.3 1.3 GO:1990923 PET complex(GO:1990923)
0.2 3.7 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.2 2.5 GO:0044295 axonal growth cone(GO:0044295)
0.2 2.9 GO:0031209 SCAR complex(GO:0031209)
0.2 3.7 GO:0005605 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.1 4.3 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1 5.9 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 1.2 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.1 2.5 GO:0000795 synaptonemal complex(GO:0000795)
0.1 0.9 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 1.2 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.1 1.1 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 0.8 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.1 1.0 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 0.6 GO:0061617 MICOS complex(GO:0061617)
0.1 3.4 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 1.3 GO:0035102 PRC1 complex(GO:0035102)
0.1 2.4 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.1 0.5 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
0.0 1.2 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 1.0 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 1.6 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 1.5 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 3.4 GO:0005814 centriole(GO:0005814)
0.0 1.0 GO:0043195 terminal bouton(GO:0043195)
0.0 4.1 GO:0030018 Z disc(GO:0030018)
0.0 1.1 GO:0035869 ciliary transition zone(GO:0035869)
0.0 0.7 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 2.2 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.6 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.2 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.4 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.3 GO:0005922 connexon complex(GO:0005922)
0.0 0.2 GO:0032019 mitochondrial cloud(GO:0032019)
0.0 1.4 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.2 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 1.0 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 2.3 GO:0014069 postsynaptic density(GO:0014069)
0.0 0.6 GO:0016605 PML body(GO:0016605)
0.0 0.6 GO:0030496 midbody(GO:0030496)
0.0 2.4 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 0.1 GO:0098833 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) extrinsic component of presynaptic membrane(GO:0098888) extrinsic component of presynaptic endocytic zone(GO:0098894)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 5.1 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.6 1.9 GO:1902945 metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902945)
0.6 1.8 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.6 3.9 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.4 2.2 GO:0039706 co-receptor binding(GO:0039706)
0.4 2.1 GO:0060182 apelin receptor activity(GO:0060182)
0.4 2.1 GO:0070412 R-SMAD binding(GO:0070412)
0.4 3.9 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.4 1.4 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.3 2.9 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.3 4.6 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828)
0.3 1.3 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.3 5.5 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.2 1.2 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.2 6.0 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.2 1.6 GO:0001130 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.2 1.0 GO:0008184 phosphorylase activity(GO:0004645) glycogen phosphorylase activity(GO:0008184)
0.2 0.8 GO:0097108 hedgehog family protein binding(GO:0097108)
0.2 0.7 GO:0072570 ADP-D-ribose binding(GO:0072570) mono-ADP-D-ribose binding(GO:0072571)
0.2 2.2 GO:0008327 methyl-CpG binding(GO:0008327)
0.2 2.6 GO:0033691 sialic acid binding(GO:0033691)
0.1 2.5 GO:0030983 mismatched DNA binding(GO:0030983)
0.1 1.9 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.1 0.6 GO:0008131 primary amine oxidase activity(GO:0008131)
0.1 2.0 GO:0019869 chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.1 1.4 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.1 2.5 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 0.8 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.1 3.4 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 2.7 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 0.3 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.1 1.9 GO:0051371 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.1 0.4 GO:0005463 UDP-glucuronic acid transmembrane transporter activity(GO:0005461) UDP-N-acetylgalactosamine transmembrane transporter activity(GO:0005463)
0.1 3.0 GO:0035064 methylated histone binding(GO:0035064)
0.1 5.5 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 0.6 GO:0098809 nitrite reductase activity(GO:0098809)
0.1 1.8 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 0.5 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.1 1.1 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 1.5 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 0.8 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.1 0.4 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.1 0.9 GO:0016775 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.1 0.3 GO:2001070 starch binding(GO:2001070)
0.1 0.6 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.1 0.5 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.1 2.7 GO:0030295 kinase activator activity(GO:0019209) protein kinase activator activity(GO:0030295)
0.1 0.4 GO:0030274 LIM domain binding(GO:0030274)
0.1 0.3 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.1 2.2 GO:0017046 peptide hormone binding(GO:0017046)
0.1 1.4 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 0.8 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.1 2.2 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 2.1 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.1 0.4 GO:0015232 heme transporter activity(GO:0015232)
0.1 0.5 GO:0030332 cyclin binding(GO:0030332)
0.1 3.5 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.2 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 1.6 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.2 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.0 0.5 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.9 GO:0048185 activin binding(GO:0048185)
0.0 1.8 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 0.6 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 1.2 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 1.5 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 1.4 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.4 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.2 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.8 GO:0042562 hormone binding(GO:0042562)
0.0 0.2 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.5 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.2 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 1.5 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 3.2 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.6 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638)
0.0 0.7 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.1 GO:0031073 vitamin D3 25-hydroxylase activity(GO:0030343) cholesterol 26-hydroxylase activity(GO:0031073)
0.0 1.3 GO:0008408 3'-5' exonuclease activity(GO:0008408)
0.0 0.2 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.3 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 3.3 GO:0019901 protein kinase binding(GO:0019901)
0.0 0.2 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.7 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.6 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.2 GO:0051117 ATPase binding(GO:0051117)
0.0 0.1 GO:0005545 1-phosphatidylinositol binding(GO:0005545)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 4.5 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.2 1.1 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.1 2.3 PID IL5 PATHWAY IL5-mediated signaling events
0.1 0.5 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.1 1.8 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.1 1.2 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 3.1 PID ERBB4 PATHWAY ErbB4 signaling events
0.1 3.4 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 0.2 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 3.4 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.1 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 1.8 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 1.6 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.0 0.4 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 1.8 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.4 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.3 PID ARF 3PATHWAY Arf1 pathway
0.0 0.9 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.2 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 1.7 NABA SECRETED FACTORS Genes encoding secreted soluble factors

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 5.5 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.2 2.3 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.2 2.6 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 2.9 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.1 1.4 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.1 1.5 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.1 2.1 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.1 1.4 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 2.1 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 1.0 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 1.1 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 2.5 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.1 1.2 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 1.5 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.1 0.5 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.1 0.4 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 1.8 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 2.3 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.3 REACTOME GAP JUNCTION TRAFFICKING Genes involved in Gap junction trafficking
0.0 3.4 REACTOME SIGNALING BY ERBB4 Genes involved in Signaling by ERBB4
0.0 1.1 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 1.3 REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0 0.2 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.4 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.0 0.8 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 0.8 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.4 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 1.0 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0 0.2 REACTOME GLYCOLYSIS Genes involved in Glycolysis