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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for phox2bb

Z-value: 0.22

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Transcription factors associated with phox2bb

Gene Symbol Gene ID Gene Info
phox2bb
ENSDARG00000091029 paired like homeobox 2Bb

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
phox2bbdr11_v1_chr14_-_17068712_170687120.058.3e-01Click!

Activity profile of phox2bb motif

Sorted Z-values of phox2bb motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_1801519 0.22 ENSDART00000188604
ENSDART00000135749
nudt4b
nudix (nucleoside diphosphate linked moiety X)-type motif 4b
chr8_-_53044300 0.18 ENSDART00000191653
nr6a1a
nuclear receptor subfamily 6, group A, member 1a
chr15_-_43284021 0.18 ENSDART00000041677
serpine2
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
chr10_-_13343831 0.15 ENSDART00000135941
il11ra
interleukin 11 receptor, alpha
chr5_+_63302660 0.14 ENSDART00000142131
si:ch73-376l24.2
si:ch73-376l24.2
chr22_-_14247276 0.13 ENSDART00000033332
si:ch211-246m6.5
si:ch211-246m6.5
chr18_+_2228737 0.13 ENSDART00000165301
rab27a
RAB27A, member RAS oncogene family
chr9_-_32177117 0.12 ENSDART00000078568
sf3b1
splicing factor 3b, subunit 1
chr22_-_10156581 0.12 ENSDART00000168304
rbck1
RanBP-type and C3HC4-type zinc finger containing 1
chr14_-_470505 0.10 ENSDART00000067147
ANKRD50
ankyrin repeat domain 50
chr9_-_27398369 0.10 ENSDART00000186499
tex30
testis expressed 30
chr22_+_2751887 0.10 ENSDART00000133652
si:dkey-20i20.11
si:dkey-20i20.11
chr21_+_25236297 0.09 ENSDART00000112783
tmem45b
transmembrane protein 45B
chr4_-_2219705 0.09 ENSDART00000131046
si:ch73-278m9.1
si:ch73-278m9.1
chr24_+_28953089 0.09 ENSDART00000153761
rnpc3
RNA-binding region (RNP1, RRM) containing 3
chr22_+_23359369 0.09 ENSDART00000170886
dennd1b
DENN/MADD domain containing 1B
chr6_+_25257728 0.09 ENSDART00000162581
kyat3
kynurenine aminotransferase 3
chr22_+_508290 0.09 ENSDART00000135403
nuak2
NUAK family, SNF1-like kinase, 2
chr1_-_31534089 0.08 ENSDART00000007770
lbx1b
ladybird homeobox 1b
chr2_-_17393216 0.08 ENSDART00000123137
st3gal3b
ST3 beta-galactoside alpha-2,3-sialyltransferase 3b
chr10_+_11261576 0.07 ENSDART00000155333
hsdl2
hydroxysteroid dehydrogenase like 2
chr8_-_49728590 0.07 ENSDART00000135714
ENSDART00000138810
ENSDART00000098319
gkap1
G kinase anchoring protein 1
chr24_+_19415124 0.07 ENSDART00000186931
sulf1
sulfatase 1
chr3_-_48716422 0.07 ENSDART00000164979
si:ch211-114m9.1
si:ch211-114m9.1
chr21_-_13123176 0.07 ENSDART00000144866
ENSDART00000024616
fam219aa
family with sequence similarity 219, member Aa
chr5_+_29851433 0.07 ENSDART00000143434
ubash3ba
ubiquitin associated and SH3 domain containing Ba
chr2_-_17392799 0.06 ENSDART00000136470
ENSDART00000141188
st3gal3b
ST3 beta-galactoside alpha-2,3-sialyltransferase 3b
chr1_+_10318089 0.05 ENSDART00000029774
pip4p1b
phosphatidylinositol-4,5-bisphosphate 4-phosphatase 1b
chr17_-_4245902 0.05 ENSDART00000151851
gdf3
growth differentiation factor 3
chr3_-_26787430 0.03 ENSDART00000087047
rab40c
RAB40c, member RAS oncogene family
chr13_+_33268657 0.03 ENSDART00000002095
tmem39b
transmembrane protein 39B
chr7_+_38811800 0.02 ENSDART00000052322
zgc:110699
zgc:110699
chr23_+_16638639 0.02 ENSDART00000143545
snphb
syntaphilin b
chr6_+_40922572 0.02 ENSDART00000133599
ENSDART00000002728
ENSDART00000145153
eif4enif1
eukaryotic translation initiation factor 4E nuclear import factor 1
chr9_+_54039006 0.02 ENSDART00000112441
tlr7
toll-like receptor 7
chr15_+_5360407 0.02 ENSDART00000110420
or112-1
odorant receptor, family A, subfamily 112, member 1
chr6_+_11249706 0.02 ENSDART00000186547
ENSDART00000193287
atg9a
ATG9 autophagy related 9 homolog A (S. cerevisiae)
chr1_-_21287724 0.02 ENSDART00000193900
npy1r
neuropeptide Y receptor Y1
chr5_+_60590796 0.02 ENSDART00000159859
tmem132e
transmembrane protein 132E
chr1_-_15797663 0.01 ENSDART00000177122
SGCZ
sarcoglycan zeta
chr8_-_33381913 0.01 ENSDART00000076420
lmx1bb
LIM homeobox transcription factor 1, beta b
chr14_-_33481428 0.01 ENSDART00000147059
ENSDART00000140001
ENSDART00000124242
ENSDART00000164836
ENSDART00000190104
ENSDART00000186833
ENSDART00000180873
lamp2
lysosomal-associated membrane protein 2
chr14_-_4556896 0.01 ENSDART00000044678
ENSDART00000192863
GABRA2
gamma-aminobutyric acid type A receptor alpha2 subunit
chr23_-_2901167 0.01 ENSDART00000165955
ENSDART00000190616
zhx3
zinc fingers and homeoboxes 3
chr15_-_39955785 0.01 ENSDART00000154556
msh5
mutS homolog 5
chr4_-_9891874 0.01 ENSDART00000067193
adm2a
adrenomedullin 2a
chr10_-_27049170 0.01 ENSDART00000143451
cnih2
cornichon family AMPA receptor auxiliary protein 2
chr6_+_24420523 0.00 ENSDART00000185461
tgfbr3
transforming growth factor, beta receptor III
chr23_-_16485190 0.00 ENSDART00000155038
si:dkeyp-100a5.4
si:dkeyp-100a5.4
chr6_+_11250033 0.00 ENSDART00000065411
ENSDART00000132677
atg9a
ATG9 autophagy related 9 homolog A (S. cerevisiae)
chr13_+_22476742 0.00 ENSDART00000078759
ENSDART00000130101
ENSDART00000137220
ENSDART00000133065
ENSDART00000147348
ldb3a
LIM domain binding 3a

Network of associatons between targets according to the STRING database.

First level regulatory network of phox2bb

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0071543 diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.0 0.1 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.0 0.1 GO:0099563 modification of synaptic structure(GO:0099563)
0.0 0.1 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0071797 LUBAC complex(GO:0071797)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0008486 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.0 0.1 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.0 0.1 GO:0030626 U12 snRNA binding(GO:0030626)
0.0 0.1 GO:0008118 N-acetyllactosaminide alpha-2,3-sialyltransferase activity(GO:0008118)