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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for pou1f1

Z-value: 0.65

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Transcription factors associated with pou1f1

Gene Symbol Gene ID Gene Info
pou1f1
ENSDARG00000058924 POU class 1 homeobox 1
pou1f1
ENSDARG00000110816 POU class 1 homeobox 1
pou1f1
ENSDARG00000115109 POU class 1 homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
pou1f1dr11_v1_chr9_-_19161982_191619820.282.6e-01Click!

Activity profile of pou1f1 motif

Sorted Z-values of pou1f1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr15_-_20939579 1.66 ENSDART00000152371
usp2a
ubiquitin specific peptidase 2a
chr2_+_49799470 1.61 ENSDART00000146325
si:ch211-190k17.19
si:ch211-190k17.19
chr8_-_13046089 1.51 ENSDART00000137784
si:dkey-208b23.5
si:dkey-208b23.5
chr3_+_26145013 1.36 ENSDART00000162546
ENSDART00000129561
atp2a1
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1
chr23_+_19813677 1.33 ENSDART00000139192
ENSDART00000142308
emd
emerin (Emery-Dreifuss muscular dystrophy)
chr8_-_44586981 1.31 ENSDART00000026831
ENSDART00000113945
rsph14
radial spoke head 14 homolog
chr5_-_54672763 1.27 ENSDART00000159009
spag8
sperm associated antigen 8
chr12_-_35944654 1.23 ENSDART00000162579
ENSDART00000164199
dnai2a
dynein, axonemal, intermediate chain 2a
chr15_-_18162647 1.21 ENSDART00000012064
pih1d2
PIH1 domain containing 2
chr4_+_9669717 1.18 ENSDART00000004604
si:dkey-153k10.9
si:dkey-153k10.9
chr5_+_42393896 1.13 ENSDART00000189550
BX548073.13

chr24_-_26328721 1.12 ENSDART00000125468
apodb
apolipoprotein Db
chr23_+_45512825 1.12 ENSDART00000064846
prelid1b
PRELI domain containing 1b
chr3_-_19200571 1.12 ENSDART00000131503
ENSDART00000012335
rfx1a
regulatory factor X, 1a (influences HLA class II expression)
chr7_+_23515966 1.09 ENSDART00000186893
ENSDART00000186189
zgc:109889
zgc:109889
chr6_+_9677420 1.09 ENSDART00000064995
sumo1
small ubiquitin-like modifier 1
chr9_-_41062412 1.08 ENSDART00000193879
ankar
ankyrin and armadillo repeat containing
chr9_-_25055722 1.05 ENSDART00000137131
dnah7
dynein, axonemal, heavy chain 7
chr8_+_17987778 1.04 ENSDART00000133429
lrriq3
leucine-rich repeats and IQ motif containing 3
chr17_-_39772999 0.97 ENSDART00000155727
pimr60
Pim proto-oncogene, serine/threonine kinase, related 60
chr23_-_19140781 0.96 ENSDART00000143580
si:ch73-381f5.2
si:ch73-381f5.2
chr11_-_27867024 0.96 ENSDART00000182136
ENSDART00000187587
eif4g3a
eukaryotic translation initiation factor 4 gamma, 3a
chr8_+_24745041 0.95 ENSDART00000148872
slc16a4
solute carrier family 16, member 4
chr14_+_46313396 0.94 ENSDART00000047525
cryba1l1
crystallin, beta A1, like 1
chr7_+_73397283 0.94 ENSDART00000174390
CABZ01081780.1

chr16_-_28856112 0.93 ENSDART00000078543
syt11b
synaptotagmin XIb
chr5_-_71705191 0.91 ENSDART00000187767
ak1
adenylate kinase 1
chr11_-_2838699 0.90 ENSDART00000066189
lhfpl5a
LHFPL tetraspan subfamily member 5a
chr2_-_1548330 0.90 ENSDART00000082155
ENSDART00000108481
ENSDART00000111272
dab1b
Dab, reelin signal transducer, homolog 1b (Drosophila)
chr3_-_39180048 0.84 ENSDART00000049720
cdk21
cyclin-dependent kinase 21
chr19_+_31873308 0.82 ENSDART00000146560
ENSDART00000133045
si:dkeyp-34f6.4
si:dkeyp-34f6.4
chr15_-_45110011 0.79 ENSDART00000182047
ENSDART00000188662
CABZ01072607.1

chr22_+_508290 0.78 ENSDART00000135403
nuak2
NUAK family, SNF1-like kinase, 2
chr6_+_40714811 0.78 ENSDART00000153868
ccdc36
coiled-coil domain containing 36
chr3_-_12026741 0.78 ENSDART00000132238
cfap70
cilia and flagella associated protein 70
chr5_+_69747417 0.77 ENSDART00000153717
si:ch211-275j6.5
si:ch211-275j6.5
chr8_+_17987215 0.75 ENSDART00000113605
lrriq3
leucine-rich repeats and IQ motif containing 3
chr13_-_37620091 0.75 ENSDART00000135875
ENSDART00000193270
ENSDART00000018064
zgc:152791
zgc:152791
chr23_-_23401305 0.75 ENSDART00000078936
her9
hairy-related 9
chr24_-_38657683 0.74 ENSDART00000154843
si:ch1073-164k15.3
si:ch1073-164k15.3
chr1_-_46244523 0.71 ENSDART00000143908
si:ch211-138g9.3
si:ch211-138g9.3
chr15_-_39955785 0.71 ENSDART00000154556
msh5
mutS homolog 5
chr14_-_24761132 0.70 ENSDART00000146299
slit3
slit homolog 3 (Drosophila)
chr5_-_41494831 0.70 ENSDART00000051081
eef2l2
eukaryotic translation elongation factor 2, like 2
chr21_-_43015383 0.70 ENSDART00000065097
dpysl3
dihydropyrimidinase-like 3
chr20_+_42881104 0.70 ENSDART00000131338
pimr110
Pim proto-oncogene, serine/threonine kinase, related 110
chr20_+_19512727 0.69 ENSDART00000063696
atraid
all-trans retinoic acid-induced differentiation factor
chr7_-_71531846 0.69 ENSDART00000111797
acer2
alkaline ceramidase 2
chr3_+_36424055 0.69 ENSDART00000170318
si:ch1073-443f11.2
si:ch1073-443f11.2
chr21_+_45841731 0.67 ENSDART00000038657
faxdc2
fatty acid hydroxylase domain containing 2
chr10_+_26747755 0.66 ENSDART00000100329
f9b
coagulation factor IXb
chr23_+_12134839 0.66 ENSDART00000128551
ENSDART00000141204
ttll9
tubulin tyrosine ligase-like family, member 9
chr14_-_1355544 0.66 ENSDART00000060417
cetn4
centrin 4
chr2_+_14992879 0.65 ENSDART00000137546
pimr55
Pim proto-oncogene, serine/threonine kinase, related 55
chr9_-_7652792 0.65 ENSDART00000137957
dnajb2
DnaJ (Hsp40) homolog, subfamily B, member 2
chr20_+_25586099 0.64 ENSDART00000063122
ENSDART00000134047
cyp2p10
cytochrome P450, family 2, subfamily P, polypeptide 10
chr16_+_28728347 0.64 ENSDART00000149240
si:dkey-24i24.3
si:dkey-24i24.3
chr2_+_19578079 0.64 ENSDART00000144413
pimr50
Pim proto-oncogene, serine/threonine kinase, related 50
chr13_+_4409294 0.63 ENSDART00000146437
si:ch211-130h14.4
si:ch211-130h14.4
chr12_+_13282797 0.61 ENSDART00000137757
ENSDART00000152397
irf9
interferon regulatory factor 9
chr24_+_32176155 0.61 ENSDART00000003745
vim
vimentin
chr2_+_36004381 0.61 ENSDART00000098706
lamc2
laminin, gamma 2
chr6_+_13117598 0.61 ENSDART00000104744
casp8l1
caspase 8, apoptosis-related cysteine peptidase, like 1
chr6_+_49551614 0.61 ENSDART00000022581
rab22a
RAB22A, member RAS oncogene family
chr18_+_27821856 0.60 ENSDART00000131712
si:ch211-222m18.4
si:ch211-222m18.4
chr10_-_14556978 0.58 ENSDART00000126643
zgc:153395
zgc:153395
chr4_-_2545310 0.57 ENSDART00000150619
ENSDART00000140760
e2f7
E2F transcription factor 7
chr19_+_1688727 0.57 ENSDART00000115136
ENSDART00000166744
dennd3a
DENN/MADD domain containing 3a
chr17_-_46817295 0.56 ENSDART00000155904
pimr24
Pim proto-oncogene, serine/threonine kinase, related 24
chr21_+_30502002 0.56 ENSDART00000043727
slc7a3a
solute carrier family 7 (cationic amino acid transporter, y+ system), member 3a
chr2_+_19522082 0.55 ENSDART00000146098
pimr49
Pim proto-oncogene, serine/threonine kinase, related 49
chr19_+_43297546 0.54 ENSDART00000168002
laptm5
lysosomal protein transmembrane 5
chr5_+_2815021 0.54 ENSDART00000020472
hpda
4-hydroxyphenylpyruvate dioxygenase a
chr7_+_26534131 0.53 ENSDART00000173980
si:dkey-62k3.5
si:dkey-62k3.5
chr16_-_21140097 0.53 ENSDART00000145837
ENSDART00000146500
si:dkey-271j15.3
si:dkey-271j15.3
chr17_-_46933567 0.53 ENSDART00000157274
pimr25
Pim proto-oncogene, serine/threonine kinase, related 25
chr15_-_39945036 0.53 ENSDART00000192481
msh5
mutS homolog 5
chr8_-_53044300 0.52 ENSDART00000191653
nr6a1a
nuclear receptor subfamily 6, group A, member 1a
chr6_-_31361546 0.51 ENSDART00000027550
ak4
adenylate kinase 4
chr15_-_46821568 0.51 ENSDART00000148525
chrd
chordin
chr6_+_52350443 0.51 ENSDART00000151612
ENSDART00000151349
si:ch211-239j9.1
si:ch211-239j9.1
chr24_-_1151334 0.51 ENSDART00000039700
ENSDART00000177356
itgb1a
integrin, beta 1a
chr15_+_9327252 0.50 ENSDART00000144381
sgcg
sarcoglycan, gamma
chr21_-_13972745 0.50 ENSDART00000143874
akna
AT-hook transcription factor
chr1_-_42289704 0.50 ENSDART00000150124
si:ch211-71k14.1
si:ch211-71k14.1
chr17_+_12285285 0.50 ENSDART00000154336
pimr174
Pim proto-oncogene, serine/threonine kinase, related 174
chr16_+_53489676 0.49 ENSDART00000074653
grinab
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1b (glutamate binding)
chr6_+_9427641 0.49 ENSDART00000022620
kalrnb
kalirin RhoGEF kinase b
chr19_-_31584444 0.49 ENSDART00000052183
zgc:111986
zgc:111986
chr24_+_744713 0.48 ENSDART00000067764
stk17a
serine/threonine kinase 17a
chr10_+_18952271 0.47 ENSDART00000146517
dpysl2b
dihydropyrimidinase-like 2b
chr23_-_6522099 0.47 ENSDART00000092214
ENSDART00000183380
ENSDART00000138020
bmp7b
bone morphogenetic protein 7b
chr25_-_4146947 0.46 ENSDART00000129268
fads2
fatty acid desaturase 2
chr20_+_40457599 0.45 ENSDART00000017553
serinc1
serine incorporator 1
chr2_+_19578446 0.45 ENSDART00000164758
pimr50
Pim proto-oncogene, serine/threonine kinase, related 50
chr5_+_41322783 0.44 ENSDART00000097546
arid3c
AT rich interactive domain 3C (BRIGHT-like)
chr23_-_16485190 0.44 ENSDART00000155038
si:dkeyp-100a5.4
si:dkeyp-100a5.4
chr2_+_44571200 0.42 ENSDART00000098132
klhl24a
kelch-like family member 24a
chr1_-_9980765 0.42 ENSDART00000142906
si:dkeyp-75b4.7
si:dkeyp-75b4.7
chr21_+_18877130 0.42 ENSDART00000136893
si:dkey-65l23.2
si:dkey-65l23.2
chr13_-_31452516 0.41 ENSDART00000193268
rtn1a
reticulon 1a
chr21_-_14811058 0.41 ENSDART00000143100
phpt1
phosphohistidine phosphatase 1
chr6_-_17112151 0.41 ENSDART00000153546
pimr17
Pim proto-oncogene, serine/threonine kinase, related 17
chr9_+_18716485 0.40 ENSDART00000135125
serp2
stress-associated endoplasmic reticulum protein family member 2
chr2_+_16160906 0.40 ENSDART00000135783
selenoj
selenoprotein J
chr6_-_16868834 0.40 ENSDART00000156503
pimr41
Pim proto-oncogene, serine/threonine kinase, related 41
chr6_+_25257728 0.40 ENSDART00000162581
kyat3
kynurenine aminotransferase 3
chr2_+_36007449 0.40 ENSDART00000161837
lamc2
laminin, gamma 2
chr1_+_25801648 0.39 ENSDART00000129471
gucy1b1
guanylate cyclase 1 soluble subunit beta 1
chr2_+_3986083 0.39 ENSDART00000188979
mkxb
mohawk homeobox b
chr7_+_26029672 0.38 ENSDART00000101126
alox12
arachidonate 12-lipoxygenase
chr20_-_9095105 0.38 ENSDART00000140792
oma1
OMA1 zinc metallopeptidase
chr6_-_17266221 0.37 ENSDART00000155448
pimr18
Pim proto-oncogene, serine/threonine kinase, related 18
chr20_+_11731039 0.37 ENSDART00000152215
ENSDART00000152585
si:ch211-155o21.3
si:ch211-155o21.3
chr14_-_470505 0.37 ENSDART00000067147
ANKRD50
ankyrin repeat domain 50
chr16_-_12173554 0.36 ENSDART00000110567
ENSDART00000155935
clstn3
calsyntenin 3
chr22_-_13851297 0.36 ENSDART00000080306
s100b
S100 calcium binding protein, beta (neural)
chr16_+_5408748 0.36 ENSDART00000160008
ENSDART00000014024
plecb
plectin b
chr4_-_948776 0.36 ENSDART00000023483
sim1b
single-minded family bHLH transcription factor 1b
chr23_+_7710447 0.36 ENSDART00000168199
kif3b
kinesin family member 3B
chr3_+_30922947 0.36 ENSDART00000184060
cldni
claudin i
chr23_+_31405497 0.36 ENSDART00000053546
sh3bgrl2
SH3 domain binding glutamate-rich protein like 2
chr16_-_27566552 0.36 ENSDART00000142102
zgc:153215
zgc:153215
chr2_-_42065069 0.36 ENSDART00000140188
cspp1b
centrosome and spindle pole associated protein 1b
chr22_-_31060579 0.36 ENSDART00000182376
cand2
cullin-associated and neddylation-dissociated 2 (putative)
chr7_+_19495905 0.35 ENSDART00000125584
ENSDART00000173774
si:ch211-212k18.8
si:ch211-212k18.8
chr16_-_30434279 0.35 ENSDART00000018504
zgc:77086
zgc:77086
chr16_+_18534834 0.35 ENSDART00000180168
rxrbb
retinoid x receptor, beta b
chr11_+_30057762 0.35 ENSDART00000164139
nhsb
Nance-Horan syndrome b (congenital cataracts and dental anomalies)
chr6_-_16735402 0.34 ENSDART00000154216
pimr44
Pim proto-oncogene, serine/threonine kinase, related 44
chr5_+_21144269 0.34 ENSDART00000028087
cds2
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2
chr12_-_28363111 0.34 ENSDART00000016283
ENSDART00000164156
psmd11b
proteasome 26S subunit, non-ATPase 11b
chr19_-_20403507 0.34 ENSDART00000052603
ENSDART00000137590
dazl
deleted in azoospermia-like
chr22_+_34663328 0.33 ENSDART00000183912
si:ch73-304f21.1
si:ch73-304f21.1
chr4_-_2219705 0.33 ENSDART00000131046
si:ch73-278m9.1
si:ch73-278m9.1
chr12_+_22560067 0.33 ENSDART00000172066
polr2a
polymerase (RNA) II (DNA directed) polypeptide A
chr12_+_3022882 0.33 ENSDART00000122905
rac3b
Rac family small GTPase 3b
chr19_+_43359075 0.33 ENSDART00000148287
ENSDART00000149856
ENSDART00000188236
ENSDART00000136695
ENSDART00000193859
yrk
Yes-related kinase
chr19_-_20403845 0.32 ENSDART00000151265
ENSDART00000147911
ENSDART00000151356
dazl
deleted in azoospermia-like
chr9_+_28598577 0.32 ENSDART00000142623
ENSDART00000135947
si:ch73-7i4.1
si:ch73-7i4.1
chr20_+_41756996 0.32 ENSDART00000186393
fam184a
family with sequence similarity 184, member A
chr7_+_59020972 0.32 ENSDART00000157873
hacd1
3-hydroxyacyl-CoA dehydratase 1
chr25_-_4525081 0.32 ENSDART00000184347
pidd1
p53-induced death domain protein 1
chr15_-_21014270 0.31 ENSDART00000154019
si:ch211-212c13.10
si:ch211-212c13.10
chr3_+_30500968 0.31 ENSDART00000103447
si:dkey-13n23.3
si:dkey-13n23.3
chr6_-_17052116 0.31 ENSDART00000156825
pimr45
Pim proto-oncogene, serine/threonine kinase, related 45
chr3_-_48716422 0.31 ENSDART00000164979
si:ch211-114m9.1
si:ch211-114m9.1
chr14_-_24391424 0.30 ENSDART00000113376
ENSDART00000126894
fam13b
family with sequence similarity 13, member B
chr10_-_26766780 0.30 ENSDART00000146666
mcf2b
MCF.2 cell line derived transforming sequence b
chr11_+_40812590 0.30 ENSDART00000186690
errfi1a
ERBB receptor feedback inhibitor 1a
chr8_-_17987547 0.29 ENSDART00000112699
ENSDART00000061747
fpgt
fucose-1-phosphate guanylyltransferase
chr16_-_12173399 0.29 ENSDART00000142574
clstn3
calsyntenin 3
chr23_-_18913032 0.29 ENSDART00000136678
si:ch211-209j10.6
si:ch211-209j10.6
chr14_-_413273 0.29 ENSDART00000163976
ENSDART00000179907
FAT4
FAT atypical cadherin 4
chr1_+_15204633 0.29 ENSDART00000188410
itln1
intelectin 1
chr20_+_4060839 0.28 ENSDART00000178565
TRIM67
tripartite motif containing 67
chr24_-_21847945 0.28 ENSDART00000189097
CR352265.4

chr16_+_46111849 0.28 ENSDART00000172232
sv2a
synaptic vesicle glycoprotein 2A
chr6_+_11989537 0.27 ENSDART00000190817
baz2ba
bromodomain adjacent to zinc finger domain, 2Ba
chr10_+_2742499 0.27 ENSDART00000122847
grk5
G protein-coupled receptor kinase 5
chr25_-_37186894 0.27 ENSDART00000191647
ENSDART00000182095
tdrd12
tudor domain containing 12
chr9_-_40765868 0.27 ENSDART00000138634
abca12
ATP-binding cassette, sub-family A (ABC1), member 12
chr8_+_28259347 0.26 ENSDART00000110857
fam212b
family with sequence similarity 212, member B
chr11_+_45436703 0.26 ENSDART00000168295
ENSDART00000173293
sos1
son of sevenless homolog 1 (Drosophila)
chr3_+_38540411 0.26 ENSDART00000154943
si:dkey-7f16.3
si:dkey-7f16.3
chr10_+_44824072 0.26 ENSDART00000162669
slc4a5
solute carrier family 4 (sodium bicarbonate cotransporter), member 5
chr12_+_47698356 0.26 ENSDART00000112010
lzts2b
leucine zipper, putative tumor suppressor 2b
chr21_+_45502773 0.26 ENSDART00000160059
ENSDART00000165704
si:dkey-223p19.2
si:dkey-223p19.2
chr1_+_49668423 0.26 ENSDART00000150880
tsga10
testis specific, 10
chr21_-_13123176 0.26 ENSDART00000144866
ENSDART00000024616
fam219aa
family with sequence similarity 219, member Aa
chr7_+_71664624 0.25 ENSDART00000170273
emilin2b
elastin microfibril interfacer 2b
chr8_+_52637507 0.25 ENSDART00000163830
si:dkey-90l8.3
si:dkey-90l8.3
chr5_-_2282256 0.25 ENSDART00000064012
ca4a
carbonic anhydrase IV a
chr7_+_19495379 0.25 ENSDART00000180514
si:ch211-212k18.8
si:ch211-212k18.8
chr3_-_15999501 0.25 ENSDART00000160668
nme3
NME/NM23 nucleoside diphosphate kinase 3
chr21_+_25236297 0.25 ENSDART00000112783
tmem45b
transmembrane protein 45B
chr6_-_50704689 0.25 ENSDART00000074100
osgn1
oxidative stress induced growth inhibitor 1
chr14_-_31854830 0.24 ENSDART00000148550
arhgef6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr2_-_9059955 0.24 ENSDART00000022768
ak5
adenylate kinase 5
chr17_-_29224908 0.24 ENSDART00000156288
si:dkey-28g23.6
si:dkey-28g23.6
chr14_+_38845674 0.24 ENSDART00000129958
hnrnpa0b
heterogeneous nuclear ribonucleoprotein A0b
chr16_+_54209504 0.24 ENSDART00000020033
xrcc1
X-ray repair complementing defective repair in Chinese hamster cells 1
chr19_-_26869103 0.24 ENSDART00000089699
prrt1
proline-rich transmembrane protein 1
chr13_+_29770837 0.23 ENSDART00000076998
pax2a
paired box 2a
chr25_+_28825657 0.23 ENSDART00000153625
nfybb
nuclear transcription factor Y, beta b
chr2_+_16487443 0.23 ENSDART00000114980
CR377211.1

chr22_-_5252005 0.23 ENSDART00000132942
ENSDART00000081801
ncln
nicalin
chr25_+_14087045 0.23 ENSDART00000155770
actc1c
actin, alpha, cardiac muscle 1c
chr16_+_28994709 0.23 ENSDART00000088023
gon4l
gon-4-like (C. elegans)
chr9_+_29548195 0.23 ENSDART00000176057
rnf17
ring finger protein 17
chr6_-_17179637 0.23 ENSDART00000153710
pimr19
Pim proto-oncogene, serine/threonine kinase, related 19
chr11_-_29737088 0.22 ENSDART00000159828
si:ch211-218g23.6
si:ch211-218g23.6
chr23_+_45200481 0.22 ENSDART00000004357
ENSDART00000111126
ENSDART00000193560
ENSDART00000190476
psip1b
PC4 and SFRS1 interacting protein 1b
chr8_+_17775247 0.22 ENSDART00000112356
si:ch211-150o23.3
si:ch211-150o23.3
chr15_-_40267485 0.22 ENSDART00000152253
kcnj13
potassium inwardly-rectifying channel, subfamily J, member 13
chr8_-_25569920 0.21 ENSDART00000136869
prex1
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
chr2_+_42072231 0.21 ENSDART00000084517
vcpip1
valosin containing protein (p97)/p47 complex interacting protein 1
chr6_-_43283122 0.21 ENSDART00000186022
frmd4ba
FERM domain containing 4Ba
chr23_-_18024543 0.21 ENSDART00000139695
pm20d1.1
peptidase M20 domain containing 1, tandem duplicate 1
chr24_+_9475809 0.21 ENSDART00000132688
si:ch211-285f17.1
si:ch211-285f17.1

Network of associatons between targets according to the STRING database.

First level regulatory network of pou1f1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.3 1.4 GO:0014724 regulation of twitch skeletal muscle contraction(GO:0014724) regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448) negative regulation of striated muscle contraction(GO:0045988) relaxation of skeletal muscle(GO:0090076)
0.3 1.1 GO:0071276 cellular response to cadmium ion(GO:0071276)
0.2 1.4 GO:0009136 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180)
0.2 0.7 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.2 1.2 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.1 0.4 GO:0035971 peptidyl-histidine dephosphorylation(GO:0035971)
0.1 0.8 GO:0060967 negative regulation of posttranscriptional gene silencing(GO:0060149) negative regulation of gene silencing by miRNA(GO:0060965) negative regulation of gene silencing by RNA(GO:0060967)
0.1 0.4 GO:0010265 SCF complex assembly(GO:0010265)
0.1 0.6 GO:0032875 regulation of DNA endoreduplication(GO:0032875) positive regulation of DNA endoreduplication(GO:0032877) DNA endoreduplication(GO:0042023)
0.1 1.2 GO:0000710 meiotic mismatch repair(GO:0000710)
0.1 0.9 GO:0097477 spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
0.1 0.7 GO:0021846 cell proliferation in forebrain(GO:0021846)
0.1 0.5 GO:0010159 specification of organ position(GO:0010159)
0.1 0.4 GO:0099543 trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by nitric oxide(GO:0099548)
0.1 0.8 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.1 0.6 GO:1902023 L-arginine import(GO:0043091) amino acid import across plasma membrane(GO:0089718) arginine import(GO:0090467) L-arginine import across plasma membrane(GO:0097638) L-arginine transport(GO:1902023) L-arginine import into cell(GO:1902765) amino acid import into cell(GO:1902837) L-arginine transmembrane transport(GO:1903400) arginine transmembrane transport(GO:1903826)
0.1 0.5 GO:0006572 tyrosine catabolic process(GO:0006572)
0.1 1.2 GO:0036158 outer dynein arm assembly(GO:0036158)
0.1 0.3 GO:0099563 modification of synaptic structure(GO:0099563)
0.1 0.6 GO:1990845 adaptive thermogenesis(GO:1990845)
0.1 0.7 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.1 1.1 GO:0051127 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 1.2 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208)
0.1 0.4 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.1 0.2 GO:0051876 pigment granule dispersal(GO:0051876)
0.1 0.2 GO:0048313 organelle inheritance(GO:0048308) Golgi inheritance(GO:0048313)
0.1 0.2 GO:0010812 negative regulation of cell-substrate adhesion(GO:0010812)
0.0 0.4 GO:0043584 nose development(GO:0043584)
0.0 0.3 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.0 0.6 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.3 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024) CDP-diacylglycerol metabolic process(GO:0046341)
0.0 0.8 GO:0006415 translational termination(GO:0006415)
0.0 1.1 GO:0071910 determination of liver left/right asymmetry(GO:0071910)
0.0 0.7 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.3 GO:0048730 epidermis morphogenesis(GO:0048730)
0.0 0.3 GO:0051013 microtubule severing(GO:0051013)
0.0 0.4 GO:0051121 lipoxygenase pathway(GO:0019372) linoleic acid metabolic process(GO:0043651) hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.2 GO:0015864 uridine transport(GO:0015862) pyrimidine nucleoside transport(GO:0015864)
0.0 1.1 GO:0060122 inner ear receptor stereocilium organization(GO:0060122)
0.0 0.3 GO:0034394 protein localization to cell surface(GO:0034394)
0.0 0.2 GO:0060118 cerebellum formation(GO:0021588) vestibular receptor cell differentiation(GO:0060114) vestibular receptor cell development(GO:0060118)
0.0 0.7 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.1 GO:0006788 heme oxidation(GO:0006788)
0.0 9.0 GO:0046777 protein autophosphorylation(GO:0046777)
0.0 0.1 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.0 0.7 GO:0007568 aging(GO:0007568)
0.0 0.5 GO:0003181 atrioventricular valve morphogenesis(GO:0003181) positive regulation of sprouting angiogenesis(GO:1903672)
0.0 0.1 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.5 GO:0006636 unsaturated fatty acid biosynthetic process(GO:0006636)
0.0 0.3 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.8 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.1 GO:2000381 negative regulation of mesoderm development(GO:2000381)
0.0 0.9 GO:0014059 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 0.1 GO:0061577 calcium ion transmembrane transport via high voltage-gated calcium channel(GO:0061577) regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
0.0 0.4 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.4 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.1 GO:0097250 mitochondrial respiratory chain supercomplex assembly(GO:0097250)
0.0 1.1 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.9 GO:0043113 receptor clustering(GO:0043113)
0.0 0.1 GO:0046958 nonassociative learning(GO:0046958) habituation(GO:0046959)
0.0 0.6 GO:0016126 sterol biosynthetic process(GO:0016126)
0.0 0.3 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.0 0.1 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.3 GO:0021654 rhombomere boundary formation(GO:0021654)
0.0 0.1 GO:0032475 otolith formation(GO:0032475)
0.0 0.1 GO:0042362 fat-soluble vitamin biosynthetic process(GO:0042362)
0.0 0.2 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.3 GO:0048246 macrophage chemotaxis(GO:0048246)
0.0 0.3 GO:0030497 fatty acid elongation(GO:0030497)
0.0 0.1 GO:1902038 positive regulation of hematopoietic stem cell differentiation(GO:1902038)
0.0 0.6 GO:0017144 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.0 0.2 GO:0006183 GTP biosynthetic process(GO:0006183)
0.0 0.5 GO:1901215 negative regulation of neuron death(GO:1901215)
0.0 0.4 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 0.1 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.0 1.5 GO:0016579 protein deubiquitination(GO:0016579)
0.0 0.1 GO:0042119 granulocyte activation(GO:0036230) neutrophil activation(GO:0042119)
0.0 0.0 GO:0045730 respiratory burst(GO:0045730) defense response to fungus(GO:0050832)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.4 GO:0031673 H zone(GO:0031673)
0.3 1.2 GO:0097255 R2TP complex(GO:0097255)
0.1 1.2 GO:0036157 outer dynein arm(GO:0036157)
0.1 0.5 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 1.5 GO:0044447 axoneme part(GO:0044447)
0.1 1.1 GO:0031209 SCAR complex(GO:0031209)
0.0 0.9 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.1 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0 0.4 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.3 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 1.1 GO:0016605 PML body(GO:0016605)
0.0 1.1 GO:0031970 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 0.4 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.1 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.0 0.2 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.2 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 0.1 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.0 0.3 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.1 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.8 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.0 0.6 GO:0030286 dynein complex(GO:0030286)
0.0 0.1 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 0.5 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.7 GO:0030426 growth cone(GO:0030426)
0.0 0.1 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.1 GO:0071914 prominosome(GO:0071914)
0.0 0.5 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0003868 4-hydroxyphenylpyruvate dioxygenase activity(GO:0003868)
0.2 1.1 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.1 1.1 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 0.3 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.1 1.4 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 0.4 GO:0101006 protein histidine phosphatase activity(GO:0101006)
0.1 0.5 GO:0098634 C-X3-C chemokine binding(GO:0019960) protein binding involved in cell-matrix adhesion(GO:0098634) collagen binding involved in cell-matrix adhesion(GO:0098639)
0.1 1.2 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.1 1.2 GO:0045503 dynein light chain binding(GO:0045503)
0.1 0.4 GO:0044548 S100 protein binding(GO:0044548)
0.1 0.6 GO:0000254 C-4 methylsterol oxidase activity(GO:0000254)
0.1 0.8 GO:0008494 translation activator activity(GO:0008494)
0.1 0.3 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.1 1.4 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 0.3 GO:0102344 3-hydroxyacyl-CoA dehydratase activity(GO:0018812) 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.1 0.6 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.1 0.8 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.1 0.6 GO:0001130 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.1 1.2 GO:0030983 mismatched DNA binding(GO:0030983)
0.1 1.1 GO:0031386 protein tag(GO:0031386)
0.1 0.8 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1 0.2 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.7 GO:0070739 protein-glutamic acid ligase activity(GO:0070739) tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.5 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.7 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.3 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.4 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.9 GO:0000339 RNA cap binding(GO:0000339)
0.0 1.1 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.1 GO:0005153 interleukin-8 receptor binding(GO:0005153)
0.0 0.1 GO:0030626 U12 snRNA binding(GO:0030626)
0.0 0.1 GO:0004134 glycogen debranching enzyme activity(GO:0004133) 4-alpha-glucanotransferase activity(GO:0004134) amylo-alpha-1,6-glucosidase activity(GO:0004135)
0.0 0.1 GO:0031544 procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.0 0.4 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.5 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.1 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.0 0.4 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.1 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.0 0.2 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.8 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.3 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.0 0.2 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.0 0.7 GO:0043022 ribosome binding(GO:0043022)
0.0 0.1 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.0 1.7 GO:0036459 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.1 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.1 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.3 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.6 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.1 1.0 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 1.1 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.7 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.6 PID AURORA B PATHWAY Aurora B signaling
0.0 0.5 PID BMP PATHWAY BMP receptor signaling
0.0 0.3 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.3 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.1 1.4 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 0.6 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 0.7 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.5 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.9 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.4 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.4 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 1.2 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.6 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.3 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.0 0.3 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.7 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 1.2 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 0.2 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.0 0.4 REACTOME KINESINS Genes involved in Kinesins
0.0 0.1 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.1 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.4 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling