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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for pou2f3

Z-value: 1.25

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Transcription factors associated with pou2f3

Gene Symbol Gene ID Gene Info
pou2f3
ENSDARG00000052387 POU class 2 homeobox 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
pou2f3dr11_v1_chr5_+_58550291_585502910.691.6e-03Click!

Activity profile of pou2f3 motif

Sorted Z-values of pou2f3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr22_+_38049130 2.97 ENSDART00000097533
wwtr1
WW domain containing transcription regulator 1
chr5_-_6567464 2.38 ENSDART00000184985
tnks1bp1
tankyrase 1 binding protein 1
chr21_+_36623162 2.36 ENSDART00000027459
grk6
G protein-coupled receptor kinase 6
chr10_+_39084354 2.14 ENSDART00000158245
si:ch73-1a9.3
si:ch73-1a9.3
chr17_-_6451801 2.10 ENSDART00000064700
fuca2
alpha-L-fucosidase 2
chr25_+_3058924 1.96 ENSDART00000029580
fth1b
ferritin, heavy polypeptide 1b
chr7_+_13582256 1.65 ENSDART00000158477
ankdd1a
ankyrin repeat and death domain containing 1A
chr21_-_37733571 1.59 ENSDART00000176214
mpp1
membrane protein, palmitoylated 1
chr18_-_29962234 1.54 ENSDART00000144996
si:ch73-103b9.2
si:ch73-103b9.2
chr7_-_1504382 1.52 ENSDART00000172770
si:zfos-405g10.4
si:zfos-405g10.4
chr18_-_20869175 1.51 ENSDART00000090079
synm
synemin, intermediate filament protein
chr21_+_42717424 1.34 ENSDART00000166936
ENSDART00000172135
sh3pxd2b
SH3 and PX domains 2B
chr2_+_36015049 1.33 ENSDART00000158276
lamc2
laminin, gamma 2
chr24_+_34970680 1.28 ENSDART00000113014
rb1cc1
RB1-inducible coiled-coil 1
chr6_-_37469775 1.25 ENSDART00000156546
plcxd1
phosphatidylinositol-specific phospholipase C, X domain containing 1
chr11_-_41132296 1.21 ENSDART00000162944
dnajc11b
DnaJ (Hsp40) homolog, subfamily C, member 11b
chr4_-_1801519 1.19 ENSDART00000188604
ENSDART00000135749
nudt4b
nudix (nucleoside diphosphate linked moiety X)-type motif 4b
chr8_+_52314542 1.12 ENSDART00000013059
ENSDART00000125241
dbnlb
drebrin-like b
chr9_-_1702648 1.11 ENSDART00000102934
hnrnpa3
heterogeneous nuclear ribonucleoprotein A3
chr19_+_1688727 1.08 ENSDART00000115136
ENSDART00000166744
dennd3a
DENN/MADD domain containing 3a
chr1_+_25801648 1.07 ENSDART00000129471
gucy1b1
guanylate cyclase 1 soluble subunit beta 1
chr9_-_8979154 1.07 ENSDART00000145266
ing1
inhibitor of growth family, member 1
chr2_+_15048410 1.07 ENSDART00000058484
cnn3b
calponin 3, acidic b
chr16_+_2820340 1.06 ENSDART00000092299
ENSDART00000192931
ENSDART00000148512
si:dkey-288i20.2
si:dkey-288i20.2
chr16_+_23961276 1.06 ENSDART00000192754
apoeb
apolipoprotein Eb
chr4_+_5341592 1.05 ENSDART00000123375
ENSDART00000067371
zgc:113263
zgc:113263
chr19_+_43579786 1.04 ENSDART00000138404
si:ch211-199g17.2
si:ch211-199g17.2
chr17_+_12075805 1.03 ENSDART00000155329
cnsta
consortin, connexin sorting protein a
chr9_-_8979468 1.02 ENSDART00000134646
ing1
inhibitor of growth family, member 1
chr14_-_34513103 0.98 ENSDART00000136306
zgc:194246
zgc:194246
chr11_-_2478374 0.98 ENSDART00000173205
si:ch73-267c23.10
si:ch73-267c23.10
chr10_+_26667475 0.97 ENSDART00000133281
ENSDART00000147013
si:ch73-52f15.5
si:ch73-52f15.5
chr17_-_15667198 0.96 ENSDART00000142972
ENSDART00000132571
ENSDART00000189936
manea
mannosidase, endo-alpha
chr20_-_46817223 0.95 ENSDART00000100336
esrrgb
estrogen-related receptor gamma b
chr12_-_10409961 0.95 ENSDART00000149521
ENSDART00000052001
eef2k
eukaryotic elongation factor 2 kinase
chr11_+_13176568 0.95 ENSDART00000125371
ENSDART00000123257
mknk1
MAP kinase interacting serine/threonine kinase 1
chr24_-_41220538 0.93 ENSDART00000150207
acvr2ba
activin A receptor type 2Ba
chr15_+_46356879 0.92 ENSDART00000154388
wu:fb18f06
wu:fb18f06
chr16_-_6944927 0.92 ENSDART00000149620
pmvk
phosphomevalonate kinase
chr5_-_25583125 0.90 ENSDART00000031665
ENSDART00000145353
anxa1a
annexin A1a
chr4_+_4509996 0.89 ENSDART00000028694
gnsa
glucosamine (N-acetyl)-6-sulfatase a
chr20_-_45812144 0.89 ENSDART00000147897
ENSDART00000147637
fermt1
fermitin family member 1
chr5_-_25582721 0.88 ENSDART00000123986
anxa1a
annexin A1a
chr8_-_43158486 0.88 ENSDART00000134801
ccdc92
coiled-coil domain containing 92
chr9_+_34319333 0.88 ENSDART00000035522
ENSDART00000146480
pou2f1b
POU class 2 homeobox 1b
chr3_+_45687266 0.86 ENSDART00000131652
gpr146
G protein-coupled receptor 146
chr22_-_4439311 0.86 ENSDART00000169317
uhrf1
ubiquitin-like with PHD and ring finger domains 1
chr18_+_31016379 0.85 ENSDART00000172461
ENSDART00000163471
uraha
urate (5-hydroxyiso-) hydrolase a
chr3_-_46410387 0.85 ENSDART00000156822
cdip1
cell death-inducing p53 target 1
chr17_+_42842632 0.84 ENSDART00000155547
ENSDART00000126087
qpct
glutaminyl-peptide cyclotransferase
chr10_-_35103208 0.84 ENSDART00000192734
zgc:110006
zgc:110006
chr14_-_15155384 0.83 ENSDART00000172666
uvssa
UV-stimulated scaffold protein A
chr17_-_26926577 0.83 ENSDART00000050202
rcan3
regulator of calcineurin 3
chr12_+_22560067 0.82 ENSDART00000172066
polr2a
polymerase (RNA) II (DNA directed) polypeptide A
chr18_-_15551360 0.81 ENSDART00000159915
ENSDART00000172690
ppfibp1b
PTPRF interacting protein, binding protein 1b (liprin beta 1)
chr15_-_31514818 0.81 ENSDART00000153978
hmgb1b
high mobility group box 1b
chr15_-_43284021 0.81 ENSDART00000041677
serpine2
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
chr22_+_38301365 0.79 ENSDART00000137339
traf5
Tnf receptor-associated factor 5
chr11_-_37997419 0.79 ENSDART00000102870
slc41a1
solute carrier family 41 (magnesium transporter), member 1
chr15_-_29354020 0.79 ENSDART00000127795
tsku
tsukushi small leucine rich proteoglycan homolog (Xenopus laevis)
chr15_+_46357080 0.78 ENSDART00000155571
ENSDART00000156541
wu:fb18f06
wu:fb18f06
chr1_+_51039558 0.78 ENSDART00000024743
dpy30
dpy-30 histone methyltransferase complex regulatory subunit
chr6_-_8264751 0.78 ENSDART00000091628
ccdc151
coiled-coil domain containing 151
chr18_-_21950751 0.75 ENSDART00000043452
tsnaxip1
translin-associated factor X interacting protein 1
chr17_-_25649079 0.73 ENSDART00000130955
ppp1cb
protein phosphatase 1, catalytic subunit, beta isozyme
chr4_-_390431 0.73 ENSDART00000067482
ENSDART00000138500
dynlt1
dynein, light chain, Tctex-type 1
chr5_-_65662996 0.72 ENSDART00000147707
camsap1b
calmodulin regulated spectrin-associated protein 1b
chr17_+_24109012 0.69 ENSDART00000156251
ehbp1
EH domain binding protein 1
chr3_-_31716157 0.68 ENSDART00000193189
ccdc47
coiled-coil domain containing 47
chr12_-_35582683 0.66 ENSDART00000167933
sec24c
SEC24 homolog C, COPII coat complex component
chr11_+_41858807 0.66 ENSDART00000161605
iffo2b
intermediate filament family orphan 2b
chr5_-_54481692 0.66 ENSDART00000165719
fbxw5
F-box and WD repeat domain containing 5
chr10_-_31015535 0.65 ENSDART00000146116
panx3
pannexin 3
chr6_+_6924637 0.65 ENSDART00000065551
ENSDART00000151393
zak
sterile alpha motif and leucine zipper containing kinase AZK
chr6_-_6346557 0.65 ENSDART00000115018
ccdc88aa
coiled-coil domain containing 88Aa
chr2_-_42558549 0.65 ENSDART00000025997
dip2cb
disco-interacting protein 2 homolog Cb
chr17_-_11466700 0.65 ENSDART00000091159
adpgk2
ADP-dependent glucokinase 2
chr20_-_3087162 0.64 ENSDART00000152495
map3k5
mitogen-activated protein kinase kinase kinase 5
chr8_-_4431971 0.64 ENSDART00000141728
ENSDART00000133519
rad9b
RAD9 checkpoint clamp component B
chr20_-_5369105 0.63 ENSDART00000114316
sptlc2b
serine palmitoyltransferase, long chain base subunit 2b
chr5_-_13206878 0.63 ENSDART00000051666
ppm1f
protein phosphatase, Mg2+/Mn2+ dependent, 1F
chr4_+_6869847 0.63 ENSDART00000036646
dock4b
dedicator of cytokinesis 4b
chr18_+_38885309 0.63 ENSDART00000041597
arpp19a
cAMP-regulated phosphoprotein 19a
chr11_+_36409457 0.63 ENSDART00000077641
cyb561d1
cytochrome b561 family, member D1
chr25_+_4787431 0.61 ENSDART00000170640
myo5c
myosin VC
chr20_-_1268863 0.61 ENSDART00000109321
ENSDART00000027119
lats1
large tumor suppressor kinase 1
chr4_-_12795436 0.60 ENSDART00000131026
ENSDART00000075127
b2m
beta-2-microglobulin
chr20_+_2589414 0.60 ENSDART00000043626
il20ra
interleukin 20 receptor, alpha
chr12_-_33706726 0.59 ENSDART00000153135
myo15b
myosin XVB
chr2_-_23572104 0.59 ENSDART00000144083
si:dkey-58b18.6
si:dkey-58b18.6
chr5_-_11809710 0.59 ENSDART00000186998
ENSDART00000181363
ENSDART00000180681
nf2a
neurofibromin 2a (merlin)
chr8_-_28274251 0.59 ENSDART00000050671
rap1aa
RAP1A, member of RAS oncogene family a
chr3_-_5067585 0.59 ENSDART00000169609
tefb
thyrotrophic embryonic factor b
chr15_-_47857687 0.58 ENSDART00000098982
ENSDART00000151594
h3f3b.1
H3 histone, family 3B.1
chr20_+_18232893 0.58 ENSDART00000189225
kctd1
potassium channel tetramerization domain containing 1
chr24_+_39186940 0.58 ENSDART00000155817
spsb3b
splA/ryanodine receptor domain and SOCS box containing 3b
chr25_+_19238175 0.58 ENSDART00000110730
ENSDART00000193619
ENSDART00000154420
ppip5k1b
diphosphoinositol pentakisphosphate kinase 1b
chr21_+_43328685 0.57 ENSDART00000109620
ENSDART00000139668
sept8a
septin 8a
chr14_-_34512859 0.57 ENSDART00000140368
si:ch211-232m8.3
si:ch211-232m8.3
chr3_-_30885250 0.57 ENSDART00000109104
kmt5c
lysine methyltransferase 5C
chr18_+_30567945 0.57 ENSDART00000078894
irf8
interferon regulatory factor 8
chr11_-_15001639 0.57 ENSDART00000170627
ENSDART00000168222
ENSDART00000171210
ENSDART00000163518
ENSDART00000168180
ENSDART00000157970
ENSDART00000169113
ENSDART00000180049
ENSDART00000188961
ENSDART00000183952
ENSDART00000193904
ENSDART00000193450
ENSDART00000186508
ENSDART00000169476
ENSDART00000162938
elavl1b
ELAV like RNA binding protein 1b
chr24_-_26981848 0.56 ENSDART00000183198
stag1b
stromal antigen 1b
chr23_-_25798099 0.55 ENSDART00000041833
fitm2
fat storage-inducing transmembrane protein 2
chr5_-_22615087 0.54 ENSDART00000146035
zgc:113208
zgc:113208
chr20_+_22045089 0.54 ENSDART00000063564
ENSDART00000187013
ENSDART00000161552
ENSDART00000174478
ENSDART00000063568
ENSDART00000152247
nmu
neuromedin U
chr1_-_36151377 0.54 ENSDART00000037516
znf827
zinc finger protein 827
chr17_+_21964472 0.53 ENSDART00000063704
ENSDART00000188904
crip3
cysteine-rich protein 3
chr2_-_55298075 0.53 ENSDART00000186404
ENSDART00000149062
rab8a
RAB8A, member RAS oncogene family
chr9_-_7212973 0.53 ENSDART00000133638
mgat4a
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr1_+_51496862 0.53 ENSDART00000150433
meis1a
Meis homeobox 1 a
chr5_+_44228526 0.53 ENSDART00000143789
TMEM8B
si:dkey-84j12.1
chr17_-_2039511 0.52 ENSDART00000160223
spint1a
serine peptidase inhibitor, Kunitz type 1 a
chr2_+_6243144 0.52 ENSDART00000058258
gng5
guanine nucleotide binding protein (G protein), gamma 5
chr1_-_56080112 0.51 ENSDART00000075469
ENSDART00000161473
c3a.6
complement component c3a, duplicate 6
chr20_-_1239596 0.51 ENSDART00000049063
ENSDART00000140650
ankrd6b
ankyrin repeat domain 6b
chr12_-_19282120 0.51 ENSDART00000153260
si:ch211-141o9.10
si:ch211-141o9.10
chr18_+_5917625 0.50 ENSDART00000169100
glg1b
golgi glycoprotein 1b
chr24_+_39614853 0.50 ENSDART00000165138
BX547934.2

chr21_-_26071773 0.50 ENSDART00000141382
rab34b
RAB34, member RAS oncogene family b
chr13_+_47821524 0.50 ENSDART00000109978
zc3h6
zinc finger CCCH-type containing 6
chr6_+_58289335 0.50 ENSDART00000177399
ralgapb
Ral GTPase activating protein, beta subunit (non-catalytic)
chr17_-_49438873 0.50 ENSDART00000004424
znf292a
zinc finger protein 292a
chr8_+_49433663 0.49 ENSDART00000140481
ENSDART00000180714
nfu1
NFU1 iron-sulfur cluster scaffold homolog (S. cerevisiae)
chr2_-_16159491 0.48 ENSDART00000110059
vav3b
vav 3 guanine nucleotide exchange factor b
chr19_-_3106447 0.48 ENSDART00000137987
si:ch211-80h18.1
si:ch211-80h18.1
chr14_-_4044545 0.47 ENSDART00000169527
snx25
sorting nexin 25
chr14_+_14662116 0.47 ENSDART00000161693
cetn2
centrin, EF-hand protein, 2
chr18_+_3579829 0.47 ENSDART00000158763
ENSDART00000182850
ENSDART00000162754
ENSDART00000178789
ENSDART00000172656
lrch3
leucine-rich repeats and calponin homology (CH) domain containing 3
chr16_+_26706519 0.47 ENSDART00000142706
virma
vir like m6A methyltransferase associated
chr3_+_1107102 0.46 ENSDART00000092690
srebf2
sterol regulatory element binding transcription factor 2
chr6_+_7322587 0.46 ENSDART00000065500
abcc4
ATP-binding cassette, sub-family C (CFTR/MRP), member 4
chr9_+_54179306 0.46 ENSDART00000189829
tmsb4x
thymosin, beta 4 x
chr11_-_45138857 0.45 ENSDART00000166501
cant1b
calcium activated nucleotidase 1b
chr22_-_347424 0.45 ENSDART00000067633
necap2
NECAP endocytosis associated 2
chr8_-_8698607 0.45 ENSDART00000046712
zgc:86609
zgc:86609
chr23_+_39606108 0.45 ENSDART00000109464
g0s2
G0/G1 switch 2
chr2_+_19633493 0.44 ENSDART00000147989
pimr54
Pim proto-oncogene, serine/threonine kinase, related 54
chr25_-_25058508 0.44 ENSDART00000087570
ENSDART00000178891
FQ311928.1

chr9_+_38481780 0.42 ENSDART00000087241
lss
lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
chr13_+_34689663 0.42 ENSDART00000133661
tasp1
taspase, threonine aspartase, 1
chr24_+_792429 0.42 ENSDART00000082523
impa2
inositol(myo)-1(or 4)-monophosphatase 2
chr20_+_29690901 0.42 ENSDART00000142669
mboat2b
membrane bound O-acyltransferase domain containing 2b
chr19_+_935565 0.42 ENSDART00000113368
RNF5
ring finger protein 5
chr21_-_3613702 0.42 ENSDART00000139194
dym
dymeclin
chr25_+_23280220 0.41 ENSDART00000153940
ptprjb.1
protein tyrosine phosphatase, receptor type, Jb, tandem duplicate 1
chr21_-_25295087 0.41 ENSDART00000087910
ENSDART00000147860
st14b
suppression of tumorigenicity 14 (colon carcinoma) b
chr24_-_39772045 0.41 ENSDART00000087441
GFOD1
si:ch211-276f18.2
chr8_-_7603516 0.41 ENSDART00000179826
ENSDART00000190153
irak1
interleukin-1 receptor-associated kinase 1
chr7_+_33424044 0.41 ENSDART00000180260
glceb
glucuronic acid epimerase b
chr1_-_7570181 0.41 ENSDART00000103588
mxa
myxovirus (influenza) resistance A
chr21_-_34032650 0.41 ENSDART00000138575
ENSDART00000047515
rnf145b
ring finger protein 145b
chr13_+_39236141 0.41 ENSDART00000111458
zgc:172136
zgc:172136
chr16_-_4531657 0.41 ENSDART00000028419
ppp1r8b
protein phosphatase 1, regulatory subunit 8b
chr8_-_47152001 0.40 ENSDART00000163922
ENSDART00000110512
ENSDART00000024320
ybx1
Y box binding protein 1
chr7_-_4110462 0.39 ENSDART00000173318
zgc:55733
zgc:55733
chr15_+_36310442 0.39 ENSDART00000154678
gmnc
geminin coiled-coil domain containing
chr10_-_27566481 0.39 ENSDART00000078920
auts2a
autism susceptibility candidate 2a
chr10_+_18911152 0.39 ENSDART00000030205
bnip3lb
BCL2 interacting protein 3 like b
chr15_+_25024685 0.38 ENSDART00000188889
BX908796.7

chr3_-_23407720 0.38 ENSDART00000155658
rapgefl1
Rap guanine nucleotide exchange factor (GEF)-like 1
chr12_+_48803098 0.38 ENSDART00000074768
ppifb
peptidylprolyl isomerase Fb
chr21_-_45073764 0.38 ENSDART00000181390
ENSDART00000063714
rapgef6
Rap guanine nucleotide exchange factor (GEF) 6
chr4_+_12292274 0.38 ENSDART00000061070
ENSDART00000150786
mkrn1
makorin, ring finger protein, 1
chr1_+_26445615 0.37 ENSDART00000180810
g3bp2
GTPase activating protein (SH3 domain) binding protein 2
chr8_-_7603700 0.37 ENSDART00000137975
irak1
interleukin-1 receptor-associated kinase 1
chr2_-_16159203 0.37 ENSDART00000153480
vav3b
vav 3 guanine nucleotide exchange factor b
chr3_+_24537023 0.37 ENSDART00000077702
sp100.1
SP110 nuclear body protein, tandem duplicate 1
chr8_+_22931427 0.37 ENSDART00000063096
sypa
synaptophysin a
chr1_-_51157660 0.37 ENSDART00000137172
jag1a
jagged 1a
chr7_+_32369026 0.36 ENSDART00000169588
lgr4
leucine-rich repeat containing G protein-coupled receptor 4
chr19_+_7424347 0.36 ENSDART00000004622
sf3b4
splicing factor 3b, subunit 4
chr12_-_11593436 0.36 ENSDART00000138954
plekha1b
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1b
chr25_+_5012791 0.35 ENSDART00000156970
si:ch73-265h17.5
si:ch73-265h17.5
chr7_-_44704910 0.35 ENSDART00000037850
dync1li2
dynein, cytoplasmic 1, light intermediate chain 2
chr20_+_29691118 0.35 ENSDART00000164121
mboat2b
membrane bound O-acyltransferase domain containing 2b
chr3_-_6519691 0.34 ENSDART00000165273
ENSDART00000179882
ENSDART00000172292
GGA3 (1 of many)
si:ch73-157i16.3
chr14_-_33312407 0.34 ENSDART00000135700
sept6
septin 6
chr16_-_31451720 0.34 ENSDART00000146886
csnk2a1
casein kinase 2, alpha 1 polypeptide
chr14_-_49133426 0.34 ENSDART00000042421
ppp2ca
protein phosphatase 2, catalytic subunit, alpha isozyme
chr3_-_39305291 0.34 ENSDART00000102674
plcd3a
phospholipase C, delta 3a
chr4_-_17263210 0.34 ENSDART00000147853
lrmp
lymphoid-restricted membrane protein
chr9_-_32847642 0.34 ENSDART00000121506
hpx
hemopexin
chr4_-_2219705 0.34 ENSDART00000131046
si:ch73-278m9.1
si:ch73-278m9.1
chr11_+_30162407 0.34 ENSDART00000190333
ENSDART00000127502
cdkl5
cyclin-dependent kinase-like 5
chr24_+_5208171 0.34 ENSDART00000155926
ENSDART00000154464
si:ch73-206p6.1
si:ch73-206p6.1
chr5_+_45138934 0.33 ENSDART00000041412
ENSDART00000136002
smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr8_+_8643901 0.33 ENSDART00000142076
ENSDART00000075624
usp11
ubiquitin specific peptidase 11
chr5_+_44190974 0.33 ENSDART00000182634
ENSDART00000190626
TMEM8B
si:dkey-84j12.1
chr5_+_6954162 0.33 ENSDART00000086666
stpg2
sperm-tail PG-rich repeat containing 2
chr18_+_20869923 0.32 ENSDART00000138471
pgpep1l
pyroglutamyl-peptidase I-like
chr13_-_2215213 0.32 ENSDART00000129773
mlip
muscular LMNA-interacting protein
chr14_-_4121052 0.32 ENSDART00000167074
irf2
interferon regulatory factor 2
chr19_+_1510971 0.32 ENSDART00000157721
SLC45A4 (1 of many)
solute carrier family 45 member 4
chr8_+_7097740 0.31 ENSDART00000159670
abtb1
ankyrin repeat and BTB (POZ) domain containing 1
chr18_+_40617717 0.31 ENSDART00000049423
zgc:158427
zgc:158427
chr13_-_34683370 0.31 ENSDART00000113661
kif16bb
kinesin family member 16Bb
chr5_+_46077710 0.31 ENSDART00000084069
ENSDART00000138055
iqgap2
IQ motif containing GTPase activating protein 2
chr16_+_25074029 0.31 ENSDART00000155465
si:dkeyp-84f3.9
si:dkeyp-84f3.9
chr3_-_60175470 0.31 ENSDART00000156597
si:ch73-364h19.1
si:ch73-364h19.1

Network of associatons between targets according to the STRING database.

First level regulatory network of pou2f3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.0 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.4 1.1 GO:0071830 chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830) intermediate-density lipoprotein particle clearance(GO:0071831)
0.3 1.0 GO:0090004 positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.3 2.1 GO:0016139 glycoside metabolic process(GO:0016137) glycoside catabolic process(GO:0016139)
0.3 1.8 GO:0032743 neutrophil apoptotic process(GO:0001781) regulation of T-helper 1 type immune response(GO:0002825) positive regulation of T-helper 1 type immune response(GO:0002827) negative regulation of type 2 immune response(GO:0002829) inflammatory cell apoptotic process(GO:0006925) regulation of prostaglandin biosynthetic process(GO:0031392) positive regulation of prostaglandin biosynthetic process(GO:0031394) regulation of phospholipase A2 activity(GO:0032429) interleukin-2 production(GO:0032623) regulation of interleukin-2 production(GO:0032663) positive regulation of interleukin-2 production(GO:0032743) myeloid cell apoptotic process(GO:0033028) regulation of neutrophil apoptotic process(GO:0033029) positive regulation of neutrophil apoptotic process(GO:0033031) regulation of myeloid cell apoptotic process(GO:0033032) positive regulation of myeloid cell apoptotic process(GO:0033034) T-helper 1 type immune response(GO:0042088) positive regulation of CD4-positive, alpha-beta T cell differentiation(GO:0043372) T-helper 1 cell differentiation(GO:0045063) positive regulation of T-helper cell differentiation(GO:0045624) regulation of T-helper 1 cell differentiation(GO:0045625) positive regulation of T-helper 1 cell differentiation(GO:0045627) regulation of T-helper 2 cell differentiation(GO:0045628) negative regulation of T-helper 2 cell differentiation(GO:0045629) positive regulation of fatty acid biosynthetic process(GO:0045723) positive regulation of alpha-beta T cell differentiation(GO:0046638) neutrophil clearance(GO:0097350) negative regulation of phospholipase A2 activity(GO:1900138) positive regulation of CD4-positive, alpha-beta T cell activation(GO:2000516) regulation of unsaturated fatty acid biosynthetic process(GO:2001279) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.3 0.8 GO:0046415 urate catabolic process(GO:0019628) urate metabolic process(GO:0046415)
0.3 2.0 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.3 1.1 GO:0099548 trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by nitric oxide(GO:0099548)
0.2 1.2 GO:1901906 diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.2 0.9 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.2 1.1 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.2 1.3 GO:0071800 podosome assembly(GO:0071800)
0.2 1.3 GO:0030242 pexophagy(GO:0030242)
0.2 0.8 GO:0018199 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186) peptidyl-glutamine modification(GO:0018199)
0.2 0.8 GO:0003418 chondrocyte differentiation involved in endochondral bone morphogenesis(GO:0003413) growth plate cartilage chondrocyte differentiation(GO:0003418)
0.2 0.6 GO:0034770 histone H4-K20 methylation(GO:0034770) histone H4-K20 trimethylation(GO:0034773)
0.2 0.6 GO:0045649 regulation of macrophage differentiation(GO:0045649)
0.1 1.0 GO:0032475 otolith formation(GO:0032475)
0.1 1.0 GO:0032732 positive regulation of interleukin-1 production(GO:0032732)
0.1 0.4 GO:1900364 negative regulation of mRNA 3'-end processing(GO:0031441) negative regulation of mRNA polyadenylation(GO:1900364)
0.1 0.5 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
0.1 0.6 GO:0070301 cellular response to hydrogen peroxide(GO:0070301)
0.1 0.8 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.1 0.6 GO:0046929 negative regulation of neurotransmitter secretion(GO:0046929) response to cAMP(GO:0051591) cellular response to cAMP(GO:0071320) negative regulation of synaptic vesicle transport(GO:1902804) negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.1 0.3 GO:0035046 pronuclear migration(GO:0035046)
0.1 0.3 GO:0048682 axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
0.1 0.7 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.1 1.0 GO:0034122 negative regulation of toll-like receptor signaling pathway(GO:0034122)
0.1 0.8 GO:0070498 interleukin-1-mediated signaling pathway(GO:0070498)
0.1 0.8 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.1 0.9 GO:0044030 regulation of DNA methylation(GO:0044030)
0.1 0.2 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.1 0.5 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.1 0.6 GO:0034389 lipid particle organization(GO:0034389)
0.1 0.6 GO:0006111 regulation of gluconeogenesis(GO:0006111)
0.1 0.4 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
0.1 1.1 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.1 0.4 GO:1903523 negative regulation of heart contraction(GO:0045822) negative regulation of blood circulation(GO:1903523)
0.1 1.0 GO:0006020 inositol metabolic process(GO:0006020)
0.1 1.1 GO:0061300 cerebellum vasculature development(GO:0061300)
0.1 1.0 GO:1904356 regulation of telomere maintenance via telomere lengthening(GO:1904356)
0.1 0.3 GO:1990167 protein K27-linked deubiquitination(GO:1990167)
0.1 0.8 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.1 0.4 GO:0009794 regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
0.1 0.2 GO:0046831 regulation of nucleobase-containing compound transport(GO:0032239) positive regulation of nucleobase-containing compound transport(GO:0032241) positive regulation of nucleocytoplasmic transport(GO:0046824) regulation of RNA export from nucleus(GO:0046831) positive regulation of RNA export from nucleus(GO:0046833) messenger ribonucleoprotein complex assembly(GO:1990120)
0.1 0.4 GO:0046685 response to arsenic-containing substance(GO:0046685)
0.1 0.4 GO:0035332 positive regulation of hippo signaling(GO:0035332)
0.1 0.8 GO:0046620 regulation of organ growth(GO:0046620)
0.1 0.3 GO:1901673 regulation of mitotic spindle assembly(GO:1901673)
0.1 0.5 GO:0006940 regulation of smooth muscle contraction(GO:0006940)
0.1 0.6 GO:0046512 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.1 0.3 GO:0031507 heterochromatin assembly(GO:0031507)
0.1 1.0 GO:0007130 synaptonemal complex assembly(GO:0007130) synaptonemal complex organization(GO:0070193)
0.1 0.8 GO:0042407 cristae formation(GO:0042407)
0.0 0.6 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.0 0.3 GO:0046532 amacrine cell differentiation(GO:0035881) regulation of photoreceptor cell differentiation(GO:0046532)
0.0 0.9 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.0 0.5 GO:0010884 positive regulation of lipid storage(GO:0010884)
0.0 0.4 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.3 GO:0006953 acute-phase response(GO:0006953)
0.0 0.5 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.0 0.1 GO:0070314 G1 to G0 transition(GO:0070314)
0.0 0.1 GO:0005997 xylulose metabolic process(GO:0005997)
0.0 0.7 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.5 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026) negative regulation of microtubule polymerization or depolymerization(GO:0031111)
0.0 0.6 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.8 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 0.9 GO:0010824 regulation of centrosome duplication(GO:0010824)
0.0 0.4 GO:0030210 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.0 0.1 GO:0090199 regulation of release of cytochrome c from mitochondria(GO:0090199) positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.0 0.7 GO:0030878 thyroid gland development(GO:0030878)
0.0 0.2 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.3 GO:0034394 protein localization to cell surface(GO:0034394)
0.0 0.5 GO:0007099 centriole replication(GO:0007099)
0.0 0.2 GO:0038065 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065)
0.0 0.3 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 2.0 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 0.1 GO:0070084 protein initiator methionine removal(GO:0070084)
0.0 0.1 GO:0036371 protein localization to T-tubule(GO:0036371)
0.0 0.3 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0 0.1 GO:0046103 adenosine catabolic process(GO:0006154) inosine metabolic process(GO:0046102) inosine biosynthetic process(GO:0046103)
0.0 1.1 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.0 0.2 GO:0006264 mitochondrial DNA replication(GO:0006264) mitochondrial DNA metabolic process(GO:0032042)
0.0 0.1 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.1 GO:0036306 embryonic heart tube elongation(GO:0036306)
0.0 0.1 GO:0035666 regulation of natural killer cell activation(GO:0032814) positive regulation of natural killer cell activation(GO:0032816) TRIF-dependent toll-like receptor signaling pathway(GO:0035666)
0.0 0.1 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.0 0.2 GO:0045050 protein insertion into ER membrane by stop-transfer membrane-anchor sequence(GO:0045050)
0.0 0.0 GO:0051589 negative regulation of neurotransmitter transport(GO:0051589)
0.0 0.5 GO:1902017 regulation of cilium assembly(GO:1902017)
0.0 1.1 GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043280)
0.0 0.2 GO:1901998 toxin transport(GO:1901998)
0.0 0.5 GO:0006595 polyamine metabolic process(GO:0006595)
0.0 0.4 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.1 GO:0006530 asparagine catabolic process(GO:0006530) asparagine catabolic process via L-aspartate(GO:0033345)
0.0 0.4 GO:0048844 artery morphogenesis(GO:0048844)
0.0 0.3 GO:0051127 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.1 GO:0008592 regulation of Toll signaling pathway(GO:0008592)
0.0 0.5 GO:0016114 terpenoid biosynthetic process(GO:0016114)
0.0 0.2 GO:0006599 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.0 0.5 GO:1903845 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.0 0.6 GO:0006284 base-excision repair(GO:0006284)
0.0 0.9 GO:0099515 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.0 0.5 GO:0048264 determination of ventral identity(GO:0048264)
0.0 0.4 GO:0021884 forebrain neuron development(GO:0021884)
0.0 0.2 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 0.2 GO:0035094 response to nicotine(GO:0035094)
0.0 0.1 GO:0061075 positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868)
0.0 1.9 GO:0008285 negative regulation of cell proliferation(GO:0008285)
0.0 0.2 GO:0045116 protein neddylation(GO:0045116)
0.0 0.1 GO:0045109 intermediate filament organization(GO:0045109) intermediate filament bundle assembly(GO:0045110)
0.0 0.4 GO:0035305 negative regulation of dephosphorylation(GO:0035305) negative regulation of protein dephosphorylation(GO:0035308)
0.0 0.3 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.0 0.1 GO:0035066 positive regulation of histone acetylation(GO:0035066)
0.0 0.2 GO:0046855 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855) inositol phosphate catabolic process(GO:0071545)
0.0 0.3 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.1 GO:0061621 glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.0 0.1 GO:0018063 protein-heme linkage(GO:0017003) protein-tetrapyrrole linkage(GO:0017006) cytochrome c-heme linkage(GO:0018063)
0.0 0.1 GO:1904030 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.0 0.6 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 0.1 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.2 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.1 GO:0097535 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535)
0.0 0.1 GO:0060729 maintenance of gastrointestinal epithelium(GO:0030277) intestinal epithelial structure maintenance(GO:0060729)
0.0 0.2 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.0 0.6 GO:0007062 sister chromatid cohesion(GO:0007062)
0.0 0.0 GO:0033212 iron assimilation(GO:0033212)
0.0 0.3 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.1 GO:0019372 lipoxygenase pathway(GO:0019372) linoleic acid metabolic process(GO:0043651) hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.3 GO:0072015 glomerular filtration(GO:0003094) glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.3 1.1 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.2 0.6 GO:0032839 dendrite cytoplasm(GO:0032839)
0.2 2.5 GO:0002102 podosome(GO:0002102)
0.2 0.6 GO:0030896 checkpoint clamp complex(GO:0030896)
0.1 1.8 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 0.6 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 0.5 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.1 0.3 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.1 0.8 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1 0.4 GO:0008091 spectrin(GO:0008091)
0.1 1.0 GO:0070187 telosome(GO:0070187)
0.1 0.2 GO:0042382 paraspeckles(GO:0042382)
0.1 0.4 GO:0070062 extracellular exosome(GO:0070062)
0.1 0.9 GO:0048179 activin receptor complex(GO:0048179)
0.1 0.6 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.1 0.6 GO:0072546 ER membrane protein complex(GO:0072546)
0.1 0.9 GO:0000792 heterochromatin(GO:0000792)
0.0 0.6 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.5 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.8 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 1.0 GO:0005921 gap junction(GO:0005921)
0.0 0.1 GO:0070209 ASTRA complex(GO:0070209)
0.0 1.1 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.2 GO:0098645 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.0 0.7 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.3 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.2 GO:0016589 NURF complex(GO:0016589)
0.0 0.5 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.0 2.3 GO:0048786 presynaptic active zone(GO:0048786)
0.0 1.1 GO:0031941 filamentous actin(GO:0031941)
0.0 0.4 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.6 GO:0008278 cohesin complex(GO:0008278)
0.0 0.4 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.2 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.5 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.1 GO:0031010 ISWI-type complex(GO:0031010)
0.0 2.3 GO:0005882 intermediate filament(GO:0005882)
0.0 0.4 GO:0098844 postsynaptic endocytic zone(GO:0098843) postsynaptic endocytic zone membrane(GO:0098844)
0.0 0.8 GO:0031105 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.1 GO:0031415 NatA complex(GO:0031415)
0.0 0.5 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.4 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.2 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.3 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 1.2 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 1.1 GO:0005814 centriole(GO:0005814)
0.0 0.2 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.4 GO:0005844 polysome(GO:0005844)
0.0 0.4 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.2 GO:0043195 terminal bouton(GO:0043195)
0.0 0.4 GO:0016605 PML body(GO:0016605)
0.0 0.1 GO:0061617 MICOS complex(GO:0061617)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0004560 alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928)
0.4 1.1 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.3 1.8 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.3 1.0 GO:0071253 connexin binding(GO:0071253)
0.2 1.2 GO:0034432 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.2 0.8 GO:0016603 glutaminyl-peptide cyclotransferase activity(GO:0016603)
0.2 0.6 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.2 2.0 GO:0008199 ferric iron binding(GO:0008199)
0.2 0.5 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.1 1.3 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175) superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 2.4 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.1 0.6 GO:0033857 inositol heptakisphosphate kinase activity(GO:0000829) diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.1 0.4 GO:0052833 inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.1 0.8 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 0.5 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.1 0.3 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.1 0.3 GO:0016920 pyroglutamyl-peptidase activity(GO:0016920)
0.1 0.4 GO:0005521 lamin binding(GO:0005521)
0.1 0.4 GO:0001948 glycoprotein binding(GO:0001948) proteoglycan binding(GO:0043394)
0.1 0.4 GO:0047464 heparosan-N-sulfate-glucuronate 5-epimerase activity(GO:0047464)
0.1 0.6 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 2.9 GO:0035064 methylated histone binding(GO:0035064)
0.1 1.7 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 0.3 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.1 0.2 GO:0030882 lipid antigen binding(GO:0030882)
0.1 0.4 GO:0019992 diacylglycerol binding(GO:0019992)
0.1 1.0 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.1 1.1 GO:0004383 guanylate cyclase activity(GO:0004383)
0.1 0.9 GO:0017002 activin-activated receptor activity(GO:0017002)
0.1 0.4 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 0.9 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.2 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
0.0 0.4 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.8 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.4 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 1.9 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.6 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.0 1.1 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 1.0 GO:0022829 wide pore channel activity(GO:0022829)
0.0 0.5 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.5 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0 0.5 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.3 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 1.0 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.5 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.6 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.6 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.7 GO:0005112 Notch binding(GO:0005112)
0.0 0.7 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0 0.2 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.0 0.4 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 0.1 GO:0061656 SUMO conjugating enzyme activity(GO:0061656)
0.0 3.6 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.5 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.8 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.2 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.4 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.5 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 1.0 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.6 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.4 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.2 GO:0038064 protein tyrosine kinase collagen receptor activity(GO:0038062) collagen receptor activity(GO:0038064)
0.0 0.1 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.0 0.1 GO:0004051 arachidonate 5-lipoxygenase activity(GO:0004051)
0.0 0.9 GO:0016776 phosphotransferase activity, phosphate group as acceptor(GO:0016776)
0.0 0.2 GO:0016775 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.0 0.1 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)
0.0 0.5 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 0.1 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.0 0.7 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.1 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.2 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.9 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.1 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.0 0.1 GO:0042809 vitamin D receptor binding(GO:0042809) thyroid hormone receptor binding(GO:0046966)
0.0 0.5 GO:0051020 GTPase binding(GO:0051020)
0.0 0.3 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.3 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.5 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.3 GO:0051393 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.0 0.4 GO:0016866 intramolecular transferase activity(GO:0016866)
0.0 0.5 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 1.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.1 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.1 GO:0004408 holocytochrome-c synthase activity(GO:0004408)
0.0 0.1 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.2 GO:0016251 obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.0 0.0 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086)
0.0 0.2 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.4 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.2 GO:0034061 DNA-directed DNA polymerase activity(GO:0003887) DNA polymerase activity(GO:0034061)
0.0 1.4 GO:0005516 calmodulin binding(GO:0005516)
0.0 0.1 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 0.5 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.2 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.4 GO:0016307 phosphatidylinositol phosphate kinase activity(GO:0016307)
0.0 0.7 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.1 GO:0019809 polyamine binding(GO:0019808) spermidine binding(GO:0019809)
0.0 3.5 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.1 GO:0005522 profilin binding(GO:0005522)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 1.3 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 1.3 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 1.6 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.0 0.9 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.6 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.6 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.8 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 1.3 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 2.4 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.0 0.3 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.6 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 0.6 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.2 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.3 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.7 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.4 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 0.2 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.2 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.2 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.6 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 2.4 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 0.6 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 0.9 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.1 0.2 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1 0.7 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 0.9 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.1 0.8 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.1 1.4 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 0.8 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.3 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 0.2 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 2.2 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 1.1 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.8 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.5 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 1.0 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 1.3 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 0.2 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.4 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.3 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.6 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.0 0.3 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.2 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.2 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.5 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 1.8 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.2 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.2 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.0 REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR Genes involved in Downstream signaling of activated FGFR
0.0 1.0 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.5 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.2 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants