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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for pou3f2a+pou3f2b+pou3f3a+pou3f3b

Z-value: 1.48

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Transcription factors associated with pou3f2a+pou3f2b+pou3f3a+pou3f3b

Gene Symbol Gene ID Gene Info
pou3f3a
ENSDARG00000042032 POU class 3 homeobox 3a
pou3f2a
ENSDARG00000070220 POU class 3 homeobox 2a
pou3f2b
ENSDARG00000076262 POU class 3 homeobox 2b
pou3f3b
ENSDARG00000095896 POU class 3 homeobox 3b
pou3f2b
ENSDARG00000112713 POU class 3 homeobox 2b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
pou3f3bdr11_v1_chr6_+_14949950_14949950-0.929.2e-08Click!
pou3f3adr11_v1_chr9_-_6661657_66616660.896.6e-07Click!
pou3f2adr11_v1_chr4_+_5741733_5741733-0.551.7e-02Click!
pou3f2bdr11_v1_chr16_+_32559821_325598210.077.9e-01Click!

Activity profile of pou3f2a+pou3f2b+pou3f3a+pou3f3b motif

Sorted Z-values of pou3f2a+pou3f2b+pou3f3a+pou3f3b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_4245902 6.47 ENSDART00000151851
gdf3
growth differentiation factor 3
chr6_+_28208973 4.11 ENSDART00000171216
ENSDART00000171377
ENSDART00000167389
ENSDART00000166988
LSM2 (1 of many)
si:ch73-14h10.2
chr19_+_20201593 3.79 ENSDART00000163026
igf2bp3
insulin-like growth factor 2 mRNA binding protein 3
chr13_-_36761379 3.67 ENSDART00000131534
ENSDART00000029824
map4k5
mitogen-activated protein kinase kinase kinase kinase 5
chr18_-_7032227 3.51 ENSDART00000127138
calub
calumenin b
chr2_-_47620806 3.49 ENSDART00000038228
ap1s3b
adaptor-related protein complex 1, sigma 3 subunit, b
chr24_-_5713799 3.45 ENSDART00000137293
dia1b
deleted in autism 1b
chr4_-_1785120 2.95 ENSDART00000103463
dnajc2
DnaJ (Hsp40) homolog, subfamily C, member 2
chr5_+_29794058 2.73 ENSDART00000045410
thy1
Thy-1 cell surface antigen
chr10_-_21362071 2.59 ENSDART00000125167
avd
avidin
chr25_+_5972690 2.59 ENSDART00000067517
si:ch211-11i22.4
si:ch211-11i22.4
chr8_+_3431671 2.50 ENSDART00000017850
ctu1
cytosolic thiouridylase subunit 1 homolog (S. pombe)
chr10_-_21362320 2.47 ENSDART00000189789
avd
avidin
chr25_-_998096 2.45 ENSDART00000164082
znf609a
zinc finger protein 609a
chr3_+_19665319 2.44 ENSDART00000007857
ENSDART00000193509
mettl2a
methyltransferase like 2A
chr7_-_41746427 2.39 ENSDART00000174232
arl8
ADP-ribosylation factor-like 8
chr15_-_4415917 2.39 ENSDART00000062874
atp1b3b
ATPase Na+/K+ transporting subunit beta 3b
chr18_+_27511976 2.38 ENSDART00000132017
ENSDART00000140781
tp53i11b
tumor protein p53 inducible protein 11b
chr16_+_27543893 2.36 ENSDART00000182421
si:ch211-197h24.6
si:ch211-197h24.6
chr18_-_48296793 2.33 ENSDART00000032184
ENSDART00000193076
CABZ01069595.1

chr11_-_35171768 2.33 ENSDART00000192896
traip
TRAF-interacting protein
chr18_+_6706140 2.26 ENSDART00000111343
lmf2a
lipase maturation factor 2a
chr20_-_23253630 2.23 ENSDART00000103365
ociad1
OCIA domain containing 1
chr2_-_38284648 2.22 ENSDART00000148281
ENSDART00000132621
si:ch211-14a17.7
si:ch211-14a17.7
chr21_-_42831033 2.22 ENSDART00000160998
stk10
serine/threonine kinase 10
chr14_+_34490445 2.21 ENSDART00000132193
ENSDART00000148044
wnt8a
wingless-type MMTV integration site family, member 8a
chr20_+_14977260 2.20 ENSDART00000186424
vamp4
vesicle-associated membrane protein 4
chr2_+_15048410 2.18 ENSDART00000058484
cnn3b
calponin 3, acidic b
chr24_-_36301072 2.18 ENSDART00000062736
coasy
CoA synthase
chr21_+_33311622 2.17 ENSDART00000163808
si:ch211-151g22.1
si:ch211-151g22.1
chr7_-_51749683 2.16 ENSDART00000083190
hdac8
histone deacetylase 8
chr5_-_39805620 2.16 ENSDART00000137801
rasgef1ba
RasGEF domain family, member 1Ba
chr14_+_30340251 2.15 ENSDART00000148448
mtus1a
microtubule associated tumor suppressor 1a
chr12_-_1031970 2.14 ENSDART00000105292
polr3e
polymerase (RNA) III (DNA directed) polypeptide E
chr6_+_33931740 2.14 ENSDART00000130492
ENSDART00000151213
orc1
origin recognition complex, subunit 1
chr17_-_18898115 2.10 ENSDART00000028044
galcb
galactosylceramidase b
chr19_+_26923110 2.09 ENSDART00000149988
nelfe
negative elongation factor complex member E
chr4_-_20108833 2.08 ENSDART00000100867
fam3c
family with sequence similarity 3, member C
chr19_-_5380770 2.08 ENSDART00000000221
krt91
keratin 91
chr21_-_7928101 2.05 ENSDART00000151543
ENSDART00000114982
f2rl1.2
coagulation factor II (thrombin) receptor-like 1, tandem duplicate 2
chr7_-_58244220 2.03 ENSDART00000180450
unm_hu7910
un-named hu7910
chr6_-_26080384 2.03 ENSDART00000157181
ENSDART00000154568
hs2st1b
heparan sulfate 2-O-sulfotransferase 1b
chr7_+_32901658 2.02 ENSDART00000115420
ano9b
anoctamin 9b
chr17_+_28628404 2.02 ENSDART00000032975
ENSDART00000143607
heatr5a
HEAT repeat containing 5a
chr14_+_9481443 2.01 ENSDART00000135449
ENSDART00000054690
st3gal5
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
chr25_-_997894 2.01 ENSDART00000169011
znf609a
zinc finger protein 609a
chr16_+_35916371 1.99 ENSDART00000167208
sh3d21
SH3 domain containing 21
chr21_-_19919020 1.98 ENSDART00000147396
ppp1r3b
protein phosphatase 1, regulatory subunit 3B
chr8_+_3434146 1.95 ENSDART00000164426
ctu1
cytosolic thiouridylase subunit 1 homolog (S. pombe)
chr6_-_49547680 1.89 ENSDART00000169678
ppp4r1l
protein phosphatase 4, regulatory subunit 1-like
chr5_-_39805874 1.89 ENSDART00000176202
ENSDART00000191683
rasgef1ba
RasGEF domain family, member 1Ba
chr9_-_12269847 1.89 ENSDART00000136558
ENSDART00000144734
ENSDART00000131766
ENSDART00000032344
nup35
nucleoporin 35
chr18_+_8917766 1.86 ENSDART00000145226
si:ch211-233h19.2
si:ch211-233h19.2
chr2_-_6065416 1.86 ENSDART00000037698
uck2b
uridine-cytidine kinase 2b
chr7_+_56735195 1.85 ENSDART00000082830
KIAA0895L
KIAA0895 like
chr21_+_18405585 1.85 ENSDART00000139318
si:dkey-1d7.3
si:dkey-1d7.3
chr19_+_42898239 1.85 ENSDART00000051724
arpp21
cAMP-regulated phosphoprotein, 21
chr11_+_43661735 1.85 ENSDART00000017912
gli2b
GLI family zinc finger 2b
chr15_+_22390076 1.84 ENSDART00000183764
oafa
OAF homolog a (Drosophila)
chr16_+_23487051 1.84 ENSDART00000145496
icn2
ictacalcin 2
chr10_+_45031398 1.84 ENSDART00000160536
gnsb
glucosamine (N-acetyl)-6-sulfatase (Sanfilippo disease IIID), b
chr16_+_42667560 1.84 ENSDART00000023452
dpy19l1l
dpy-19-like 1, like (H. sapiens)
chr19_+_42071033 1.83 ENSDART00000169067
ENSDART00000183436
nfyc
nuclear transcription factor Y, gamma
chr24_-_25442342 1.82 ENSDART00000177140
ENSDART00000138215
phex
phosphate regulating endopeptidase homolog, X-linked
chr21_-_2814709 1.80 ENSDART00000097664
SEMA4D
semaphorin 4D
chr11_-_42230491 1.78 ENSDART00000164423
CABZ01030862.1

chr10_+_16911951 1.78 ENSDART00000164933
UNC13B (1 of many)
unc-13 homolog B
chr12_+_27232173 1.77 ENSDART00000193714
tmem106a
transmembrane protein 106A
chr16_-_26525901 1.77 ENSDART00000110260
l3mbtl1b
l(3)mbt-like 1b (Drosophila)
chr10_+_15255198 1.76 ENSDART00000139047
ENSDART00000172107
ENSDART00000183413
ENSDART00000185314
vldlr
very low density lipoprotein receptor
chr3_+_32416948 1.76 ENSDART00000157324
ENSDART00000154267
ENSDART00000186094
ENSDART00000155860
ENSDART00000156986
prrg2
proline rich Gla (G-carboxyglutamic acid) 2
chr14_+_22132388 1.76 ENSDART00000109065
ccng1
cyclin G1
chr6_+_40563848 1.75 ENSDART00000154766
si:ch73-15b2.5
si:ch73-15b2.5
chr10_+_15454745 1.75 ENSDART00000129441
ENSDART00000123935
ENSDART00000163446
ENSDART00000087680
ENSDART00000193752
erbin
erbb2 interacting protein
chr17_+_11372531 1.75 ENSDART00000130975
ENSDART00000149366
timm9
translocase of inner mitochondrial membrane 9 homolog
chr9_+_19623363 1.73 ENSDART00000142471
ENSDART00000147662
ENSDART00000136053
pdxka
pyridoxal (pyridoxine, vitamin B6) kinase a
chr8_-_2529878 1.71 ENSDART00000056767
acaa2
acetyl-CoA acyltransferase 2
chr3_+_19248973 1.71 ENSDART00000174668
smarca4a
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4a
chr18_+_27489595 1.71 ENSDART00000182018
tp53i11b
tumor protein p53 inducible protein 11b
chr16_+_41060161 1.70 ENSDART00000141130
scap
SREBF chaperone
chr17_+_24320861 1.70 ENSDART00000179858
otx1
orthodenticle homeobox 1
chr8_+_2543525 1.69 ENSDART00000129569
ENSDART00000128227
gle1
GLE1 RNA export mediator homolog (yeast)
chr12_+_27231607 1.69 ENSDART00000066270
tmem106a
transmembrane protein 106A
chr7_-_51749895 1.68 ENSDART00000175523
ENSDART00000189639
hdac8
histone deacetylase 8
chr11_+_30253968 1.66 ENSDART00000157272
ENSDART00000003475
ppef1
protein phosphatase, EF-hand calcium binding domain 1
chr17_-_23895026 1.65 ENSDART00000122108
pdzd8
PDZ domain containing 8
chr10_+_41945890 1.65 ENSDART00000063013
ENSDART00000128313
tmem120b
transmembrane protein 120B
chr12_-_18578218 1.64 ENSDART00000125803
zdhhc4
zinc finger, DHHC-type containing 4
chr16_-_44945224 1.63 ENSDART00000156921
ncam3
neural cell adhesion molecule 3
chr23_+_24501918 1.62 ENSDART00000078824
szrd1
SUZ RNA binding domain containing 1
chr24_-_23716097 1.60 ENSDART00000084954
ENSDART00000129028
pign
phosphatidylinositol glycan anchor biosynthesis, class N
chr13_+_11828516 1.59 ENSDART00000110141
sufu
suppressor of fused homolog (Drosophila)
chr22_-_3284023 1.59 ENSDART00000170992
si:zfos-943e10.1
si:zfos-943e10.1
chr2_-_40890264 1.59 ENSDART00000123886
uggt1
UDP-glucose glycoprotein glucosyltransferase 1
chr12_+_27231212 1.58 ENSDART00000133023
ENSDART00000123739
tmem106a
transmembrane protein 106A
chr19_+_32979132 1.58 ENSDART00000169469
ENSDART00000171782
ENSDART00000180705
ENSDART00000179326
ENSDART00000193791
spire1a
spire-type actin nucleation factor 1a
chr15_-_45356635 1.57 ENSDART00000192000
CABZ01068246.1

chr3_-_30888415 1.56 ENSDART00000124458
kmt5c
lysine methyltransferase 5C
chr19_-_47587719 1.56 ENSDART00000111108
CABZ01071972.1

chr12_-_33746111 1.55 ENSDART00000127203
llgl2
lethal giant larvae homolog 2 (Drosophila)
chr7_-_8712148 1.55 ENSDART00000065488
tex261
testis expressed 261
chr22_+_25236657 1.53 ENSDART00000138012
zgc:172218
zgc:172218
chr16_-_39267185 1.52 ENSDART00000058550
ENSDART00000133642
gpd1l
glycerol-3-phosphate dehydrogenase 1 like
chr16_-_46578523 1.52 ENSDART00000131061
si:dkey-152b24.6
si:dkey-152b24.6
chr21_-_18275226 1.52 ENSDART00000126672
ENSDART00000135239
brd3a
bromodomain containing 3a
chr12_+_19958845 1.51 ENSDART00000193248
ercc4
excision repair cross-complementation group 4
chr2_+_31437547 1.50 ENSDART00000141170
stam
signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
chr23_+_26026383 1.50 ENSDART00000141553
pfkfb1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr20_+_34502606 1.50 ENSDART00000139739
gorab
golgin, rab6-interacting
chr9_+_33154841 1.49 ENSDART00000132465
dopey2
dopey family member 2
chr10_+_2842923 1.49 ENSDART00000181895
ykt6
YKT6 v-SNARE homolog (S. cerevisiae)
chr18_-_12295092 1.49 ENSDART00000033248
fam107b
family with sequence similarity 107, member B
chr23_-_31436524 1.47 ENSDART00000140519
zgc:153284
zgc:153284
chr15_+_37936458 1.46 ENSDART00000154491
si:ch73-380l3.2
si:ch73-380l3.2
chr17_-_27235797 1.46 ENSDART00000130080
asap3
ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
chr2_-_26596794 1.46 ENSDART00000134685
ENSDART00000056787
zgc:113691
zgc:113691
chr9_-_7287375 1.46 ENSDART00000128352
mitd1
MIT, microtubule interacting and transport, domain containing 1
chr13_-_35761266 1.45 ENSDART00000190217
erlec1
endoplasmic reticulum lectin 1
chr9_-_34509997 1.44 ENSDART00000169114
ppp2r3b
protein phosphatase 2, regulatory subunit B'', beta
chr17_-_26537928 1.44 ENSDART00000155692
ENSDART00000122366
ccser2a
coiled-coil serine-rich protein 2a
chr5_-_8682590 1.44 ENSDART00000142762
zgc:153352
zgc:153352
chr3_-_79366 1.43 ENSDART00000114289
zgc:165518
zgc:165518
chr20_+_33994580 1.43 ENSDART00000061729
si:dkey-97o5.1
si:dkey-97o5.1
chr15_+_19990068 1.42 ENSDART00000154033
ENSDART00000054428
zgc:112083
zgc:112083
chr9_+_38588081 1.42 ENSDART00000031127
ENSDART00000131784
snx4
sorting nexin 4
chr9_-_11676491 1.40 ENSDART00000022358
zc3h15
zinc finger CCCH-type containing 15
chr23_-_17429775 1.39 ENSDART00000043076
ppdpfb
pancreatic progenitor cell differentiation and proliferation factor b
chr5_-_24542726 1.39 ENSDART00000182975
trmt2a
tRNA methyltransferase 2 homolog A
chr3_+_52953489 1.38 ENSDART00000125136
dsn1
DSN1 homolog, MIS12 kinetochore complex component
chr9_-_7287128 1.38 ENSDART00000176281
ENSDART00000065803
mitd1
MIT, microtubule interacting and transport, domain containing 1
chr19_+_42806812 1.37 ENSDART00000108775
ENSDART00000151653
ubp1
upstream binding protein 1
chr5_-_15264007 1.37 ENSDART00000180641
gnb1l
guanine nucleotide binding protein (G protein), beta polypeptide 1-like
chr20_+_28364742 1.37 ENSDART00000103355
rhov
ras homolog family member V
chr16_-_47381519 1.36 ENSDART00000032188
ENSDART00000150136
si:dkey-256h2.1
si:dkey-256h2.1
chr20_+_32523576 1.36 ENSDART00000147319
scml4
Scm polycomb group protein like 4
chr15_-_34871968 1.35 ENSDART00000191980
mgat1a
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase a
chr18_+_3579829 1.35 ENSDART00000158763
ENSDART00000182850
ENSDART00000162754
ENSDART00000178789
ENSDART00000172656
lrch3
leucine-rich repeats and calponin homology (CH) domain containing 3
chr9_+_29520696 1.34 ENSDART00000144430
fdx1
ferredoxin 1
chr15_-_28587490 1.34 ENSDART00000186196
ssh2a
slingshot protein phosphatase 2a
chr5_+_3927989 1.33 ENSDART00000030125
znhit3
zinc finger, HIT-type containing 3
chr23_+_2714949 1.33 ENSDART00000105284
ncoa6
nuclear receptor coactivator 6
chr17_-_8692722 1.32 ENSDART00000148931
ENSDART00000192891
ctbp2a
C-terminal binding protein 2a
chr10_-_2788668 1.31 ENSDART00000131749
ENSDART00000124356
ENSDART00000085031
ash2l
ash2 (absent, small, or homeotic)-like (Drosophila)
chr25_-_12805295 1.31 ENSDART00000157629
ca5a
carbonic anhydrase Va
chr3_+_27606505 1.29 ENSDART00000150953
usp7
ubiquitin specific peptidase 7 (herpes virus-associated)
chr17_+_6538733 1.29 ENSDART00000193712
slc5a6b
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
chr2_+_9821757 1.29 ENSDART00000018408
ENSDART00000141227
ENSDART00000144681
ENSDART00000148227
anxa13l
annexin A13, like
chr1_+_5422439 1.28 ENSDART00000055047
ENSDART00000142248
stk16
serine/threonine kinase 16
chr6_-_31987940 1.28 ENSDART00000132280
ror1
receptor tyrosine kinase-like orphan receptor 1
chr24_+_10898671 1.27 ENSDART00000106272
si:dkey-37o8.1
si:dkey-37o8.1
chr3_+_17933132 1.27 ENSDART00000104299
ENSDART00000162144
ENSDART00000162242
ENSDART00000166289
ENSDART00000171101
ENSDART00000164853
cnp
2',3'-cyclic nucleotide 3' phosphodiesterase
chr1_+_49415281 1.27 ENSDART00000015007
taf5
TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr16_+_30002605 1.27 ENSDART00000160555
sema6e
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6E
chr22_-_26289549 1.27 ENSDART00000043774
sde2
SDE2 telomere maintenance homolog (S. pombe)
chr9_+_30421489 1.26 ENSDART00000145025
ENSDART00000132058
zgc:113314
zgc:113314
chr24_+_21174523 1.26 ENSDART00000183849
naa50
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr25_-_13558172 1.25 ENSDART00000139970
ENSDART00000133789
ENSDART00000144426
ano10b
anoctamin 10b
chr21_+_13383413 1.25 ENSDART00000151345
zgc:113162
zgc:113162
chr11_+_3499111 1.25 ENSDART00000113096
ENSDART00000171621
pusl1
pseudouridylate synthase-like 1
chr21_+_21205667 1.24 ENSDART00000058311
rictorb
RPTOR independent companion of MTOR, complex 2b
chr7_-_39360325 1.23 ENSDART00000098033
ENSDART00000173695
ENSDART00000173466
ENSDART00000173734
ambra1a
autophagy/beclin-1 regulator 1a
chr3_+_32789605 1.23 ENSDART00000171895
tbc1d10b
TBC1 domain family, member 10b
chr2_-_32512648 1.22 ENSDART00000170674
abcf2a
ATP-binding cassette, sub-family F (GCN20), member 2a
chr10_+_36662640 1.21 ENSDART00000063359
ucp2
uncoupling protein 2
chr8_-_16675464 1.21 ENSDART00000191982
osbpl9
oxysterol binding protein-like 9
chr1_+_23560216 1.21 ENSDART00000187824
ncapg
non-SMC condensin I complex, subunit G
chr4_-_13931508 1.21 ENSDART00000067174
zcrb1
zinc finger CCHC-type and RNA binding motif 1
chr20_-_9123052 1.21 ENSDART00000125133
mysm1
Myb-like, SWIRM and MPN domains 1
chr6_+_21993613 1.20 ENSDART00000160750
ENSDART00000083070
thumpd3
THUMP domain containing 3
chr17_-_12249990 1.20 ENSDART00000177889
ENSDART00000155545
ahctf1
AT hook containing transcription factor 1
chr13_+_29926326 1.19 ENSDART00000131609
cuedc2
CUE domain containing 2
chr22_+_25248961 1.19 ENSDART00000143079
si:ch211-226h8.11
si:ch211-226h8.11
chr22_+_789795 1.19 ENSDART00000185230
ENSDART00000192538
ENSDART00000171045
ENSDART00000180188
cry1bb
cryptochrome circadian clock 1bb
chr3_-_30488063 1.19 ENSDART00000055393
ENSDART00000151367
med25
mediator complex subunit 25
chr4_+_76304911 1.19 ENSDART00000172734
ENSDART00000161850
si:ch73-389k6.1
si:ch73-389k6.1
chr20_+_45620076 1.19 ENSDART00000113806
hnrnpa0l
heterogeneous nuclear ribonucleoprotein A0, like
chr9_+_55379283 1.18 ENSDART00000192728
nlgn4b
neuroligin 4b
chr22_+_25236888 1.18 ENSDART00000037286
zgc:172218
zgc:172218
chr14_-_26482096 1.18 ENSDART00000187280
smad5
SMAD family member 5
chr7_+_9326234 1.18 ENSDART00000104536
chsy1
chondroitin sulfate synthase 1
chr11_+_35171406 1.16 ENSDART00000110839
mon1a
MON1 secretory trafficking family member A
chr6_-_41028698 1.16 ENSDART00000134293
trub2
TruB pseudouridine (psi) synthase family member 2
chr18_-_16907436 1.15 ENSDART00000146464
swap70b
switching B cell complex subunit SWAP70b
chr7_-_24875421 1.14 ENSDART00000173920
adad2
adenosine deaminase domain containing 2
chr11_+_34523132 1.14 ENSDART00000192257
zmat3
zinc finger, matrin-type 3
chr23_-_29668286 1.14 ENSDART00000129248
clstn1
calsyntenin 1
chr10_+_7719796 1.12 ENSDART00000191795
ggcx
gamma-glutamyl carboxylase
chr17_-_49339677 1.12 ENSDART00000047857
orc3
origin recognition complex, subunit 3
chr8_-_15211164 1.12 ENSDART00000110550
bcar3
BCAR3, NSP family adaptor protein
chr17_-_31819837 1.11 ENSDART00000160281
abraxas2b
abraxas 2b, BRISC complex subunit
chr5_+_24087035 1.11 ENSDART00000183644
tp53
tumor protein p53
chr23_+_43718865 1.11 ENSDART00000175192
anapc10
anaphase promoting complex subunit 10
chr18_+_14307059 1.11 ENSDART00000186558
zgc:173742
zgc:173742
chr19_-_34011340 1.11 ENSDART00000172618
elmo1
engulfment and cell motility 1 (ced-12 homolog, C. elegans)
chr4_-_13931293 1.10 ENSDART00000067172
zcrb1
zinc finger CCHC-type and RNA binding motif 1
chr4_-_70883663 1.10 ENSDART00000170959
si:ch211-108c17.2
si:ch211-108c17.2
chr23_+_21492151 1.09 ENSDART00000025487
icmt
isoprenylcysteine carboxyl methyltransferase
chr9_-_13871935 1.09 ENSDART00000146597
raph1a
Ras association (RalGDS/AF-6) and pleckstrin homology domains 1a
chr18_+_6641542 1.09 ENSDART00000160379
c2cd5
C2 calcium-dependent domain containing 5
chr15_+_1534644 1.09 ENSDART00000130413
smc4
structural maintenance of chromosomes 4

Network of associatons between targets according to the STRING database.

First level regulatory network of pou3f2a+pou3f2b+pou3f3a+pou3f3b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 6.5 GO:0038107 nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145)
0.8 3.1 GO:1903292 protein localization to Golgi membrane(GO:1903292)
0.7 4.5 GO:0032447 tRNA wobble position uridine thiolation(GO:0002143) protein urmylation(GO:0032447)
0.7 2.2 GO:0039015 spinal cord anterior/posterior patterning(GO:0021512) cell proliferation involved in pronephros development(GO:0039015) cell proliferation involved in kidney development(GO:0072111)
0.7 2.0 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.6 1.8 GO:0018211 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.6 2.2 GO:0090161 Golgi ribbon formation(GO:0090161)
0.5 1.6 GO:0034773 histone H4-K20 methylation(GO:0034770) histone H4-K20 trimethylation(GO:0034773)
0.5 1.5 GO:1901255 nucleotide-excision repair involved in interstrand cross-link repair(GO:1901255)
0.5 3.8 GO:0070933 histone H4 deacetylation(GO:0070933)
0.5 1.4 GO:0071896 protein localization to adherens junction(GO:0071896)
0.4 1.3 GO:0042822 pyridoxal phosphate metabolic process(GO:0042822) pyridoxal phosphate biosynthetic process(GO:0042823)
0.4 2.0 GO:0018197 peptidyl-aspartic acid modification(GO:0018197) peptidyl-aspartic acid hydroxylation(GO:0042264)
0.4 1.6 GO:1904590 regulation of protein import into nucleus(GO:0042306) negative regulation of protein import into nucleus(GO:0042308) negative regulation of nucleocytoplasmic transport(GO:0046823) negative regulation of protein localization to nucleus(GO:1900181) regulation of protein import(GO:1904589) negative regulation of protein import(GO:1904590)
0.4 1.5 GO:0046168 NADH oxidation(GO:0006116) glycerol-3-phosphate catabolic process(GO:0046168)
0.4 1.1 GO:0043525 regulation of transposition, RNA-mediated(GO:0010525) negative regulation of transposition, RNA-mediated(GO:0010526) transposition, RNA-mediated(GO:0032197) positive regulation of neuron apoptotic process(GO:0043525) positive regulation of neuron death(GO:1901216)
0.4 1.1 GO:0009162 deoxyribonucleoside monophosphate metabolic process(GO:0009162)
0.3 2.1 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.3 1.7 GO:0060295 regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.3 1.7 GO:0051659 maintenance of mitochondrion location(GO:0051659)
0.3 1.6 GO:0097355 protein localization to heterochromatin(GO:0097355)
0.3 1.6 GO:0048855 adenohypophysis morphogenesis(GO:0048855)
0.3 2.9 GO:1902038 positive regulation of hematopoietic stem cell differentiation(GO:1902038)
0.3 1.3 GO:0051182 biotin transport(GO:0015878) pantothenate transmembrane transport(GO:0015887) coenzyme transport(GO:0051182)
0.3 1.3 GO:0071962 establishment of mitotic sister chromatid cohesion(GO:0034087) mitotic sister chromatid cohesion, centromeric(GO:0071962)
0.3 1.6 GO:0010719 photoreceptor cell morphogenesis(GO:0008594) negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.3 2.2 GO:0070073 clustering of voltage-gated calcium channels(GO:0070073)
0.3 1.2 GO:0035521 monoubiquitinated protein deubiquitination(GO:0035520) monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.3 2.1 GO:0040014 regulation of multicellular organism growth(GO:0040014)
0.3 1.7 GO:0021634 optic nerve formation(GO:0021634)
0.3 1.1 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.3 2.0 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.3 0.8 GO:0009191 ribonucleoside diphosphate catabolic process(GO:0009191) pyrimidine ribonucleoside diphosphate metabolic process(GO:0009193) UDP metabolic process(GO:0046048)
0.3 0.8 GO:0030423 targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.3 0.3 GO:2000275 regulation of oxidative phosphorylation uncoupler activity(GO:2000275)
0.3 1.3 GO:1904086 regulation of epiboly involved in gastrulation with mouth forming second(GO:1904086)
0.3 2.1 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.3 1.8 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.3 3.1 GO:0006999 nuclear pore organization(GO:0006999)
0.3 2.1 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.2 0.7 GO:0046099 guanine salvage(GO:0006178) GMP salvage(GO:0032263) guanine biosynthetic process(GO:0046099)
0.2 1.9 GO:0044211 CTP salvage(GO:0044211)
0.2 3.0 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.2 2.0 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.2 1.1 GO:0039703 viral genome replication(GO:0019079) negative stranded viral RNA replication(GO:0039689) viral RNA genome replication(GO:0039694) RNA replication(GO:0039703) multi-organism metabolic process(GO:0044033) multi-organism biosynthetic process(GO:0044034)
0.2 2.0 GO:0061588 calcium activated phospholipid scrambling(GO:0061588)
0.2 0.7 GO:0006409 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.2 0.9 GO:0021825 pallium development(GO:0021543) cerebral cortex cell migration(GO:0021795) cerebral cortex tangential migration(GO:0021800) cerebral cortex tangential migration using cell-axon interactions(GO:0021824) substrate-dependent cerebral cortex tangential migration(GO:0021825) gonadotrophin-releasing hormone neuronal migration to the hypothalamus(GO:0021828) hypothalamic tangential migration using cell-axon interactions(GO:0021856) cerebral cortex development(GO:0021987)
0.2 1.1 GO:0010828 positive regulation of glucose transport(GO:0010828)
0.2 1.1 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.2 1.2 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.2 0.8 GO:0016332 establishment or maintenance of polarity of embryonic epithelium(GO:0016332) cell-cell junction maintenance(GO:0045217)
0.2 1.6 GO:0033206 meiotic cytokinesis(GO:0033206) polar body extrusion after meiotic divisions(GO:0040038)
0.2 1.2 GO:0060876 semicircular canal formation(GO:0060876)
0.2 1.1 GO:0048714 positive regulation of glial cell differentiation(GO:0045687) positive regulation of oligodendrocyte differentiation(GO:0048714)
0.2 1.3 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.2 1.1 GO:0017187 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.2 1.7 GO:0045444 fat cell differentiation(GO:0045444)
0.2 1.3 GO:0098937 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937) anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
0.2 0.7 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.2 0.7 GO:0035633 maintenance of blood-brain barrier(GO:0035633)
0.2 0.9 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.2 1.7 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998)
0.2 1.2 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
0.2 1.5 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.2 0.5 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.2 0.8 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.2 1.0 GO:0048260 positive regulation of receptor-mediated endocytosis(GO:0048260) protein localization to early endosome(GO:1902946)
0.2 2.2 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.2 0.9 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.2 1.2 GO:1990845 adaptive thermogenesis(GO:1990845)
0.2 0.8 GO:0072575 hepatocyte proliferation(GO:0072574) epithelial cell proliferation involved in liver morphogenesis(GO:0072575)
0.1 1.6 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.1 0.4 GO:1903334 regulation of protein folding(GO:1903332) positive regulation of protein folding(GO:1903334) regulation of chaperone-mediated protein folding(GO:1903644) positive regulation of chaperone-mediated protein folding(GO:1903646)
0.1 0.8 GO:0019427 acetate metabolic process(GO:0006083) acetyl-CoA biosynthetic process from acetate(GO:0019427)
0.1 0.4 GO:0060912 cardiac cell fate specification(GO:0060912)
0.1 2.2 GO:2000344 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.1 1.3 GO:0070301 cellular response to hydrogen peroxide(GO:0070301)
0.1 0.8 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.1 0.6 GO:0032655 interleukin-12 production(GO:0032615) regulation of interleukin-12 production(GO:0032655)
0.1 1.7 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.1 0.8 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.1 0.5 GO:0060829 negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060829)
0.1 0.8 GO:0006465 signal peptide processing(GO:0006465)
0.1 1.6 GO:0035268 protein mannosylation(GO:0035268) mannosylation(GO:0097502)
0.1 0.6 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.1 0.8 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.1 2.2 GO:2000401 regulation of lymphocyte migration(GO:2000401)
0.1 0.5 GO:0036306 embryonic heart tube elongation(GO:0036306)
0.1 0.5 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.1 1.7 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.1 1.8 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.1 1.2 GO:0038203 TORC2 signaling(GO:0038203)
0.1 0.3 GO:1904983 transmembrane glycine transport from cytosol to mitochondrion(GO:1904983)
0.1 0.9 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.1 1.9 GO:0006265 DNA topological change(GO:0006265)
0.1 2.7 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.1 1.0 GO:0006622 protein targeting to lysosome(GO:0006622)
0.1 0.3 GO:0044650 virion attachment to host cell(GO:0019062) adhesion of symbiont to host(GO:0044406) adhesion of symbiont to host cell(GO:0044650)
0.1 0.5 GO:0006535 cysteine biosynthetic process from serine(GO:0006535) hydrogen sulfide biosynthetic process(GO:0070814)
0.1 1.8 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.1 0.9 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.1 0.3 GO:0019364 pyridine nucleotide catabolic process(GO:0019364) NAD catabolic process(GO:0019677) pyridine-containing compound catabolic process(GO:0072526)
0.1 2.8 GO:0045454 cell redox homeostasis(GO:0045454)
0.1 1.3 GO:0071501 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.1 1.1 GO:0036388 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.1 0.8 GO:0009217 dGTP catabolic process(GO:0006203) purine nucleoside triphosphate catabolic process(GO:0009146) purine deoxyribonucleotide catabolic process(GO:0009155) purine deoxyribonucleoside triphosphate catabolic process(GO:0009217) dGTP metabolic process(GO:0046070)
0.1 0.4 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.1 0.9 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 0.2 GO:0032640 tumor necrosis factor production(GO:0032640) tumor necrosis factor superfamily cytokine production(GO:0071706)
0.1 1.1 GO:0006382 adenosine to inosine editing(GO:0006382)
0.1 0.3 GO:0061188 regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188)
0.1 1.5 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1 1.3 GO:2000223 regulation of BMP signaling pathway involved in heart jogging(GO:2000223)
0.1 0.6 GO:0097250 mitochondrial respiratory chain supercomplex assembly(GO:0097250)
0.1 1.4 GO:0051639 actin filament network formation(GO:0051639)
0.1 0.3 GO:0045822 negative regulation of heart contraction(GO:0045822) negative regulation of blood circulation(GO:1903523)
0.1 0.4 GO:2001106 regulation of guanyl-nucleotide exchange factor activity(GO:1905097) regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.1 0.6 GO:0006741 NADP biosynthetic process(GO:0006741)
0.1 0.7 GO:2000758 positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.1 0.6 GO:0045905 positive regulation of translational termination(GO:0045905)
0.1 1.0 GO:1902101 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.1 2.0 GO:0006688 glycosphingolipid biosynthetic process(GO:0006688)
0.1 0.4 GO:0008592 regulation of Toll signaling pathway(GO:0008592)
0.1 0.6 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.1 1.0 GO:0006020 inositol metabolic process(GO:0006020)
0.1 0.5 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.1 1.5 GO:0002574 thrombocyte differentiation(GO:0002574)
0.1 0.5 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.1 0.2 GO:0098773 skin epidermis development(GO:0098773)
0.1 0.7 GO:0006450 regulation of translational fidelity(GO:0006450)
0.1 0.5 GO:0006537 glutamate biosynthetic process(GO:0006537) glutamine catabolic process(GO:0006543)
0.1 0.5 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.1 0.8 GO:0070989 oxidative demethylation(GO:0070989)
0.1 2.2 GO:0030488 tRNA methylation(GO:0030488)
0.1 4.4 GO:0051028 mRNA transport(GO:0051028)
0.1 0.4 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.1 1.3 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.1 1.8 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.1 0.6 GO:0071684 hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.1 0.2 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.1 1.4 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.1 0.9 GO:0000186 activation of MAPKK activity(GO:0000186)
0.1 0.7 GO:0048041 cell-substrate adherens junction assembly(GO:0007045) focal adhesion assembly(GO:0048041) regulation of focal adhesion assembly(GO:0051893) regulation of cell-substrate junction assembly(GO:0090109)
0.1 0.4 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.1 0.9 GO:0061055 myotome development(GO:0061055)
0.1 0.2 GO:0002834 response to tumor cell(GO:0002347) natural killer cell cytokine production(GO:0002370) immune response to tumor cell(GO:0002418) natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of natural killer cell cytokine production(GO:0002727) positive regulation of natural killer cell cytokine production(GO:0002729) positive regulation of response to biotic stimulus(GO:0002833) regulation of response to tumor cell(GO:0002834) positive regulation of response to tumor cell(GO:0002836) regulation of immune response to tumor cell(GO:0002837) positive regulation of immune response to tumor cell(GO:0002839) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860) positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
0.1 0.9 GO:0016926 protein desumoylation(GO:0016926)
0.1 0.5 GO:0032094 response to food(GO:0032094)
0.1 0.2 GO:0042481 regulation of odontogenesis(GO:0042481)
0.1 0.2 GO:0071514 genetic imprinting(GO:0071514)
0.1 0.2 GO:0006526 arginine biosynthetic process(GO:0006526)
0.1 0.2 GO:0051657 maintenance of organelle location(GO:0051657)
0.1 0.3 GO:0061641 chromatin remodeling at centromere(GO:0031055) CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.1 0.7 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.1 0.4 GO:0000730 DNA recombinase assembly(GO:0000730)
0.1 1.3 GO:0009214 cyclic nucleotide catabolic process(GO:0009214)
0.1 0.2 GO:0098923 retrograde trans-synaptic signaling by soluble gas(GO:0098923) retrograde trans-synaptic signaling by nitric oxide(GO:0098924)
0.0 2.3 GO:0031647 regulation of protein stability(GO:0031647)
0.0 0.7 GO:0034453 microtubule anchoring(GO:0034453)
0.0 1.3 GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling(GO:0014068)
0.0 0.3 GO:0035313 wound healing, spreading of epidermal cells(GO:0035313) negative regulation of ruffle assembly(GO:1900028)
0.0 1.7 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.1 GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504)
0.0 1.3 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.5 GO:0072498 embryonic skeletal joint development(GO:0072498)
0.0 1.0 GO:0010390 histone monoubiquitination(GO:0010390)
0.0 0.2 GO:0019860 uracil catabolic process(GO:0006212) uracil metabolic process(GO:0019860)
0.0 0.7 GO:0001522 pseudouridine synthesis(GO:0001522)
0.0 0.4 GO:0090148 membrane fission(GO:0090148)
0.0 0.2 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.3 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 1.5 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.1 GO:0030237 female sex determination(GO:0030237) male sex determination(GO:0030238)
0.0 0.8 GO:0006623 protein targeting to vacuole(GO:0006623)
0.0 0.5 GO:0042531 tyrosine phosphorylation of STAT protein(GO:0007260) regulation of tyrosine phosphorylation of STAT protein(GO:0042509) positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
0.0 0.6 GO:0055117 regulation of cardiac muscle contraction(GO:0055117)
0.0 0.6 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.1 GO:0071586 CAAX-box protein processing(GO:0071586) CAAX-box protein maturation(GO:0080120)
0.0 0.8 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 1.4 GO:1902593 protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744) single-organism nuclear import(GO:1902593)
0.0 0.5 GO:0006490 oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.0 2.0 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 0.8 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.0 4.2 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.3 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.9 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 0.4 GO:0030259 lipid glycosylation(GO:0030259)
0.0 0.3 GO:0016576 histone dephosphorylation(GO:0016576) negative regulation of signal transduction in absence of ligand(GO:1901099) regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001239) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.0 0.4 GO:0002097 tRNA wobble base modification(GO:0002097)
0.0 0.3 GO:0032228 regulation of synaptic transmission, GABAergic(GO:0032228)
0.0 0.8 GO:0016925 protein sumoylation(GO:0016925)
0.0 0.7 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.0 0.5 GO:0009408 response to heat(GO:0009408)
0.0 0.8 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 0.4 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.0 0.3 GO:0018410 C-terminal protein amino acid modification(GO:0018410)
0.0 0.2 GO:0051785 positive regulation of mitotic nuclear division(GO:0045840) positive regulation of nuclear division(GO:0051785)
0.0 0.6 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.6 GO:0007257 activation of JUN kinase activity(GO:0007257) positive regulation of JUN kinase activity(GO:0043507)
0.0 0.8 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.2 GO:0097341 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.0 0.1 GO:0031443 fast-twitch skeletal muscle fiber contraction(GO:0031443)
0.0 0.8 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.9 GO:0006284 base-excision repair(GO:0006284)
0.0 0.1 GO:0032196 transposition(GO:0032196)
0.0 1.4 GO:0050906 detection of stimulus involved in sensory perception(GO:0050906)
0.0 0.3 GO:0033077 T cell differentiation in thymus(GO:0033077) thymocyte aggregation(GO:0071594)
0.0 1.0 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.2 GO:0034435 steroid esterification(GO:0034433) sterol esterification(GO:0034434) cholesterol esterification(GO:0034435)
0.0 0.8 GO:0006289 nucleotide-excision repair(GO:0006289)
0.0 0.6 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 6.9 GO:0000398 RNA splicing, via transesterification reactions(GO:0000375) RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.0 0.3 GO:0035493 SNARE complex assembly(GO:0035493)
0.0 0.1 GO:0060300 microglial cell activation(GO:0001774) regulation of cytokine activity(GO:0060300) regulation of receptor binding(GO:1900120) regulation of chemokine activity(GO:1900136)
0.0 0.4 GO:0007020 microtubule nucleation(GO:0007020)
0.0 0.5 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.0 1.2 GO:0007052 mitotic spindle organization(GO:0007052)
0.0 0.7 GO:0043652 engulfment of apoptotic cell(GO:0043652)
0.0 0.8 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.9 GO:0032465 regulation of cytokinesis(GO:0032465)
0.0 0.7 GO:0030917 midbrain-hindbrain boundary development(GO:0030917)
0.0 0.5 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.0 1.7 GO:0033339 pectoral fin development(GO:0033339)
0.0 0.7 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.1 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 1.1 GO:1902668 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)
0.0 2.0 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 0.3 GO:0060021 palate development(GO:0060021)
0.0 0.3 GO:0036376 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.0 0.5 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.6 GO:0031629 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.0 0.4 GO:0030500 regulation of bone mineralization(GO:0030500) regulation of biomineral tissue development(GO:0070167)
0.0 3.6 GO:0032259 methylation(GO:0032259)
0.0 0.7 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 0.5 GO:1903844 regulation of transforming growth factor beta receptor signaling pathway(GO:0017015) regulation of cellular response to transforming growth factor beta stimulus(GO:1903844)
0.0 2.1 GO:0051604 protein maturation(GO:0051604)
0.0 0.8 GO:0001946 lymphangiogenesis(GO:0001946)
0.0 1.5 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.0 1.5 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.0 0.4 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.0 0.2 GO:0051310 metaphase plate congression(GO:0051310)
0.0 0.1 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.1 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.0 0.1 GO:0032231 regulation of actin filament bundle assembly(GO:0032231)
0.0 0.2 GO:0034427 nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'(GO:0034427)
0.0 0.2 GO:0048570 notochord morphogenesis(GO:0048570)
0.0 1.1 GO:0032272 negative regulation of actin filament polymerization(GO:0030837) negative regulation of protein polymerization(GO:0032272)
0.0 0.1 GO:0006693 prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693)
0.0 0.1 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.0 0.1 GO:0006797 polyphosphate metabolic process(GO:0006797) polyphosphate catabolic process(GO:0006798)
0.0 2.2 GO:0031032 actomyosin structure organization(GO:0031032)
0.0 0.3 GO:0043523 regulation of neuron apoptotic process(GO:0043523)
0.0 0.2 GO:0071456 cellular response to hypoxia(GO:0071456)
0.0 0.8 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.3 GO:0033334 fin morphogenesis(GO:0033334)
0.0 0.2 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.7 GO:0061640 cytoskeleton-dependent cytokinesis(GO:0061640)
0.0 0.3 GO:0006906 vesicle fusion(GO:0006906)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:0097189 apoptotic body(GO:0097189)
0.5 3.5 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.5 1.4 GO:0000941 condensed nuclear chromosome inner kinetochore(GO:0000941)
0.4 1.7 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.4 1.5 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.4 1.5 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.3 1.4 GO:0035301 Hedgehog signaling complex(GO:0035301)
0.3 2.9 GO:0032021 NELF complex(GO:0032021)
0.3 0.8 GO:0070578 RISC-loading complex(GO:0070578)
0.3 3.3 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.3 1.8 GO:0048500 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.3 1.5 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.3 1.3 GO:0031415 NatA complex(GO:0031415)
0.3 1.0 GO:0070209 ASTRA complex(GO:0070209)
0.2 2.4 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
0.2 1.9 GO:0000796 condensin complex(GO:0000796)
0.2 0.7 GO:0034456 CURI complex(GO:0032545) UTP-C complex(GO:0034456)
0.2 0.9 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.2 0.8 GO:0005787 signal peptidase complex(GO:0005787)
0.2 1.9 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.2 0.9 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.2 1.8 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.2 0.8 GO:0033553 rDNA heterochromatin(GO:0033553)
0.2 1.7 GO:0098835 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) extrinsic component of presynaptic membrane(GO:0098888) extrinsic component of presynaptic endocytic zone(GO:0098894)
0.1 1.0 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.1 0.4 GO:0072380 TRC complex(GO:0072380)
0.1 0.4 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.1 0.8 GO:0005915 cell-cell adherens junction(GO:0005913) zonula adherens(GO:0005915)
0.1 1.1 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.1 2.9 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.1 0.5 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.1 1.1 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 0.4 GO:0033065 Rad51C-XRCC3 complex(GO:0033065)
0.1 2.0 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 1.6 GO:0034361 very-low-density lipoprotein particle(GO:0034361)
0.1 0.7 GO:0000439 core TFIIH complex(GO:0000439)
0.1 0.8 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.1 2.0 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.1 1.0 GO:0032300 mismatch repair complex(GO:0032300)
0.1 2.1 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.1 3.0 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 0.8 GO:0070938 contractile ring(GO:0070938)
0.1 1.9 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 1.8 GO:0008287 protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.1 0.9 GO:0031080 nuclear pore outer ring(GO:0031080)
0.1 3.4 GO:0005637 nuclear inner membrane(GO:0005637)
0.1 0.4 GO:0070724 BMP receptor complex(GO:0070724)
0.1 0.4 GO:0031501 mannosyltransferase complex(GO:0031501)
0.1 0.7 GO:0016272 prefoldin complex(GO:0016272)
0.1 0.7 GO:0000974 Prp19 complex(GO:0000974)
0.1 0.7 GO:0071005 U2-type precatalytic spliceosome(GO:0071005)
0.1 0.3 GO:0044609 DBIRD complex(GO:0044609)
0.1 0.3 GO:0008274 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.1 0.3 GO:0033061 DNA recombinase mediator complex(GO:0033061)
0.1 2.4 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 0.5 GO:0000109 nucleotide-excision repair complex(GO:0000109)
0.1 1.2 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 0.4 GO:0045261 proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.1 0.5 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.1 3.5 GO:0031901 early endosome membrane(GO:0031901)
0.1 0.4 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.1 2.1 GO:0005643 nuclear pore(GO:0005643)
0.1 0.9 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 1.7 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.1 GO:0005592 collagen type XI trimer(GO:0005592)
0.0 0.5 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.7 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 1.7 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.2 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.2 GO:0000938 GARP complex(GO:0000938)
0.0 3.1 GO:0030117 membrane coat(GO:0030117) coated membrane(GO:0048475)
0.0 0.2 GO:1990071 TRAPPII protein complex(GO:1990071)
0.0 1.7 GO:0030139 endocytic vesicle(GO:0030139)
0.0 1.4 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.2 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 1.7 GO:0005876 spindle microtubule(GO:0005876)
0.0 4.1 GO:0005802 trans-Golgi network(GO:0005802)
0.0 1.2 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.0 0.2 GO:0055087 Ski complex(GO:0055087)
0.0 1.4 GO:0035097 histone methyltransferase complex(GO:0035097)
0.0 0.6 GO:0030057 desmosome(GO:0030057)
0.0 0.9 GO:0030496 midbody(GO:0030496)
0.0 0.7 GO:0008278 cohesin complex(GO:0008278)
0.0 2.2 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.8 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.6 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 1.3 GO:0016592 mediator complex(GO:0016592)
0.0 0.7 GO:0005940 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 2.4 GO:0005882 intermediate filament(GO:0005882)
0.0 1.2 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.1 GO:0043194 axon initial segment(GO:0043194)
0.0 1.0 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.1 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 6.2 GO:0000139 Golgi membrane(GO:0000139)
0.0 1.5 GO:0005871 kinesin complex(GO:0005871)
0.0 2.0 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 1.9 GO:0005884 actin filament(GO:0005884)
0.0 0.2 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.1 GO:0043034 costamere(GO:0043034)
0.0 0.0 GO:0032044 DSIF complex(GO:0032044)
0.0 0.1 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.3 GO:0030667 secretory granule membrane(GO:0030667)
0.0 4.4 GO:0005794 Golgi apparatus(GO:0005794)
0.0 0.4 GO:0043204 perikaryon(GO:0043204)
0.0 0.3 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.5 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 5.1 GO:0009374 biotin binding(GO:0009374)
0.7 2.0 GO:0004394 heparan sulfate 2-O-sulfotransferase activity(GO:0004394)
0.7 2.0 GO:0047291 lactosylceramide alpha-2,3-sialyltransferase activity(GO:0047291)
0.6 3.7 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.6 2.4 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.6 1.7 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.6 1.7 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.5 1.6 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.5 1.6 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.5 2.0 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.4 1.3 GO:0004113 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity(GO:0004113)
0.4 1.5 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.4 1.5 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
0.4 1.8 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.3 1.4 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.3 1.6 GO:0008046 axon guidance receptor activity(GO:0008046)
0.3 1.3 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.3 1.6 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.3 1.2 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.3 1.1 GO:0008488 gamma-glutamyl carboxylase activity(GO:0008488)
0.3 3.8 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.3 2.1 GO:0015057 thrombin receptor activity(GO:0015057)
0.3 1.5 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.2 2.7 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.2 0.7 GO:0004422 hypoxanthine phosphoribosyltransferase activity(GO:0004422)
0.2 1.9 GO:0004849 uridine kinase activity(GO:0004849)
0.2 1.4 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.2 2.0 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.2 0.9 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
0.2 2.2 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.2 0.9 GO:0004092 carnitine O-acetyltransferase activity(GO:0004092)
0.2 0.8 GO:0033857 inositol heptakisphosphate kinase activity(GO:0000829) diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.2 0.8 GO:0070883 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296) pre-miRNA binding(GO:0070883)
0.2 0.9 GO:0008311 double-stranded DNA exodeoxyribonuclease activity(GO:0008309) double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.2 0.8 GO:0050218 propionate-CoA ligase activity(GO:0050218)
0.2 0.5 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.2 1.1 GO:0000995 transcription factor activity, core RNA polymerase III binding(GO:0000995)
0.1 1.9 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.1 0.4 GO:0052717 tRNA-specific adenosine-34 deaminase activity(GO:0052717)
0.1 1.4 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.1 0.8 GO:0008832 dGTPase activity(GO:0008832) triphosphoric monoester hydrolase activity(GO:0016793)
0.1 1.7 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 2.0 GO:2001069 glycogen binding(GO:2001069)
0.1 2.2 GO:0033691 sialic acid binding(GO:0033691)
0.1 1.2 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.1 3.3 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 0.5 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.1 2.2 GO:0032190 acrosin binding(GO:0032190)
0.1 1.2 GO:0010340 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.1 5.1 GO:0000049 tRNA binding(GO:0000049)
0.1 3.8 GO:0000030 mannosyltransferase activity(GO:0000030)
0.1 2.1 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 2.2 GO:0070566 adenylyltransferase activity(GO:0070566)
0.1 2.4 GO:0001671 ATPase activator activity(GO:0001671)
0.1 0.8 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.1 0.5 GO:0061656 SUMO conjugating enzyme activity(GO:0061656)
0.1 1.9 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.1 0.7 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.1 1.5 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.1 0.5 GO:0004122 cystathionine beta-synthase activity(GO:0004122)
0.1 1.1 GO:0008251 double-stranded RNA adenosine deaminase activity(GO:0003726) tRNA-specific adenosine deaminase activity(GO:0008251)
0.1 2.0 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 0.5 GO:0008432 JUN kinase binding(GO:0008432)
0.1 0.7 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.1 1.3 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1 3.1 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 1.4 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 0.4 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.1 0.9 GO:0035925 AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 1.6 GO:0045159 myosin II binding(GO:0045159)
0.1 0.9 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.1 0.4 GO:0030504 inorganic diphosphate transmembrane transporter activity(GO:0030504)
0.1 0.5 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.1 2.2 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 2.2 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 0.3 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.1 1.4 GO:0072542 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.1 0.2 GO:0034618 arginine binding(GO:0034618)
0.1 0.9 GO:0004526 ribonuclease P activity(GO:0004526)
0.1 0.6 GO:0016421 CoA carboxylase activity(GO:0016421) ligase activity, forming carbon-carbon bonds(GO:0016885)
0.1 0.4 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.1 0.5 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.1 1.0 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 0.5 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.1 0.2 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.1 0.5 GO:0016416 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.1 0.5 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 0.9 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.1 1.2 GO:0070122 isopeptidase activity(GO:0070122)
0.1 2.1 GO:0017147 Wnt-protein binding(GO:0017147)
0.1 1.7 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.1 0.9 GO:0016875 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.1 0.4 GO:0008118 N-acetyllactosaminide alpha-2,3-sialyltransferase activity(GO:0008118)
0.1 1.1 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.1 0.4 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.1 0.5 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 0.2 GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263) beta-1,3-galactosyltransferase activity(GO:0048531)
0.1 0.3 GO:0033842 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity(GO:0033842)
0.1 0.7 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.1 1.2 GO:0070411 I-SMAD binding(GO:0070411)
0.1 0.2 GO:0034736 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
0.1 1.5 GO:0005246 calcium channel regulator activity(GO:0005246)
0.1 1.4 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.1 0.7 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1 1.0 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.1 1.2 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 5.3 GO:0019208 phosphatase regulator activity(GO:0019208)
0.1 0.8 GO:0031386 protein tag(GO:0031386)
0.0 2.3 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.5 GO:0046527 glucosyltransferase activity(GO:0046527)
0.0 0.8 GO:0045134 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.0 0.8 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.4 GO:0004359 glutaminase activity(GO:0004359)
0.0 1.1 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 1.9 GO:0005109 frizzled binding(GO:0005109)
0.0 2.9 GO:0032934 sterol binding(GO:0032934)
0.0 0.2 GO:0002058 uracil binding(GO:0002058) pyrimidine nucleobase binding(GO:0002061) dihydropyrimidine dehydrogenase (NADP+) activity(GO:0017113)
0.0 1.0 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0 0.6 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.8 GO:0016251 obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.0 0.6 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.4 GO:0030172 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.0 1.6 GO:0030145 manganese ion binding(GO:0030145)
0.0 0.4 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.3 GO:0035198 miRNA binding(GO:0035198)
0.0 1.3 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.4 GO:0005522 profilin binding(GO:0005522)
0.0 0.6 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 1.2 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.7 GO:0030552 cAMP binding(GO:0030552)
0.0 2.2 GO:0005178 integrin binding(GO:0005178)
0.0 1.9 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.4 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.0 6.2 GO:0005125 cytokine activity(GO:0005125)
0.0 0.9 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 1.6 GO:0031072 heat shock protein binding(GO:0031072)
0.0 0.4 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.2 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 2.3 GO:0030674 protein binding, bridging(GO:0030674)
0.0 0.4 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.4 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 6.7 GO:0042393 histone binding(GO:0042393)
0.0 0.7 GO:0015299 solute:proton antiporter activity(GO:0015299)
0.0 0.1 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.8 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.4 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.9 GO:0017069 snRNA binding(GO:0017069)
0.0 0.7 GO:0004698 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.0 1.3 GO:0008173 RNA methyltransferase activity(GO:0008173)
0.0 0.2 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.1 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.1 GO:0048763 ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763)
0.0 0.3 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.0 8.9 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.3 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.8 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.4 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.2 GO:0070628 proteasome binding(GO:0070628)
0.0 0.8 GO:0042287 MHC protein binding(GO:0042287)
0.0 0.4 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.3 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.2 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 2.5 GO:0042803 protein homodimerization activity(GO:0042803)
0.0 0.5 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.2 GO:0038187 pattern recognition receptor activity(GO:0038187)
0.0 0.1 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.0 1.1 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 2.9 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.6 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 0.8 GO:0032451 demethylase activity(GO:0032451)
0.0 0.4 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.5 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.0 0.0 GO:0097643 amylin receptor activity(GO:0097643)
0.0 2.1 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.3 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.5 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.9 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.1 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.2 GO:0019894 kinesin binding(GO:0019894)
0.0 0.4 GO:0019239 deaminase activity(GO:0019239)
0.0 0.1 GO:0004309 exopolyphosphatase activity(GO:0004309)
0.0 0.1 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.0 0.3 GO:0008483 transaminase activity(GO:0008483)
0.0 1.1 GO:0019955 cytokine binding(GO:0019955)
0.0 1.0 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.1 GO:0004997 thyrotropin-releasing hormone receptor activity(GO:0004997)
0.0 1.5 GO:0008081 phosphoric diester hydrolase activity(GO:0008081)
0.0 1.5 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 ST JAK STAT PATHWAY Jak-STAT Pathway
0.1 1.9 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 5.1 PID TNF PATHWAY TNF receptor signaling pathway
0.1 1.2 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 1.8 PID REELIN PATHWAY Reelin signaling pathway
0.1 0.6 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.1 3.0 PID AURORA B PATHWAY Aurora B signaling
0.1 1.1 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1 1.5 PID BMP PATHWAY BMP receptor signaling
0.1 3.4 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.1 0.7 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1 1.5 PID IL2 1PATHWAY IL2-mediated signaling events
0.1 1.7 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.1 1.9 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.7 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 7.2 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 3.8 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.9 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.9 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.0 1.3 PID E2F PATHWAY E2F transcription factor network
0.0 0.2 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 1.3 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.3 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.8 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.0 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.4 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.7 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.5 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 1.3 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.3 PID FOXO PATHWAY FoxO family signaling
0.0 0.3 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.2 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.3 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.3 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.3 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.2 2.2 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.2 2.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.2 0.8 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 2.1 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.1 1.8 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 1.1 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 2.2 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.1 1.2 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.1 2.7 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.1 0.8 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.1 1.6 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 0.8 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.1 1.2 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 3.6 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 1.5 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 3.1 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.1 2.1 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.1 2.4 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.1 1.3 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.1 1.1 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.1 0.8 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.1 0.8 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.1 1.4 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.1 1.5 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.1 0.4 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.1 2.7 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.1 1.2 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.1 0.9 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.1 1.0 REACTOME SIGNALING BY NOTCH1 Genes involved in Signaling by NOTCH1
0.1 0.7 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.4 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 1.0 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.5 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.8 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.6 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 2.6 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 3.5 REACTOME DIABETES PATHWAYS Genes involved in Diabetes pathways
0.0 0.8 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.0 0.9 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.8 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.5 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.2 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.5 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.0 0.3 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.7 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 0.6 REACTOME TRNA AMINOACYLATION Genes involved in tRNA Aminoacylation
0.0 0.2 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 1.1 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.0 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.5 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.1 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.2 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.6 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.1 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.2 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters