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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for pou5f3

Z-value: 0.44

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Transcription factors associated with pou5f3

Gene Symbol Gene ID Gene Info
pou5f3
ENSDARG00000044774 POU domain, class 5, transcription factor 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
pou5f3dr11_v1_chr21_-_13690712_136907120.292.4e-01Click!

Activity profile of pou5f3 motif

Sorted Z-values of pou5f3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr10_-_44560165 0.73 ENSDART00000181217
ENSDART00000076084
npm2b
nucleophosmin/nucleoplasmin, 2b
chr23_-_33709964 0.69 ENSDART00000143333
ENSDART00000130338
pou6f1
POU class 6 homeobox 1
chr24_+_7322116 0.53 ENSDART00000005804
XRCC2
X-ray repair cross complementing 2
chr5_-_30074332 0.51 ENSDART00000147963
bco2a
beta-carotene oxygenase 2a
chr1_-_55068941 0.49 ENSDART00000152143
ENSDART00000152590
peli1a
pellino E3 ubiquitin protein ligase 1a
chr24_+_3328354 0.40 ENSDART00000147468
bdh1
3-hydroxybutyrate dehydrogenase, type 1
chr8_-_16592491 0.37 ENSDART00000101655
calr
calreticulin
chr18_+_7543347 0.32 ENSDART00000103467
arf5
ADP-ribosylation factor 5
chr4_-_8903240 0.29 ENSDART00000129983
mpped1
metallophosphoesterase domain containing 1
chr7_-_24644893 0.27 ENSDART00000048921
rgp1
GP1 homolog, RAB6A GEF complex partner 1
chr7_-_58843193 0.27 ENSDART00000167231
mrpl15
mitochondrial ribosomal protein L15
chr24_-_21989406 0.27 ENSDART00000032963
apoob
apolipoprotein O, b
chr5_+_29715040 0.22 ENSDART00000192563
ddx31
DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
chr2_-_20120904 0.22 ENSDART00000186002
ENSDART00000124724
dpydb
dihydropyrimidine dehydrogenase b
chr8_+_43016714 0.21 ENSDART00000142671
rassf2a
Ras association (RalGDS/AF-6) domain family member 2a
chr5_+_29714786 0.20 ENSDART00000148314
ddx31
DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
chr9_+_12444494 0.12 ENSDART00000102430
tmem41aa
transmembrane protein 41aa
chr11_+_7528599 0.11 ENSDART00000171813
adgrl2a
adhesion G protein-coupled receptor L2a
chr17_+_28670132 0.09 ENSDART00000076344
ENSDART00000164981
ENSDART00000182851
hectd1
HECT domain containing 1
chr8_+_41038141 0.09 ENSDART00000075620
gpat2
glycerol-3-phosphate acyltransferase 2, mitochondrial
chr22_-_30881738 0.08 ENSDART00000059965
si:dkey-49n23.1
si:dkey-49n23.1
chr11_-_36001495 0.07 ENSDART00000190330
itpr1b
inositol 1,4,5-trisphosphate receptor, type 1b
chr6_-_55399214 0.06 ENSDART00000168367
ctsa
cathepsin A
chr24_-_20641000 0.06 ENSDART00000166135
zbtb47b
zinc finger and BTB domain containing 47b
chr24_-_7321928 0.05 ENSDART00000167570
ENSDART00000045150
actr3b
ARP3 actin related protein 3 homolog B
chr19_-_43552252 0.05 ENSDART00000138308
gpr186
G protein-coupled receptor 186
chr3_-_34032019 0.05 ENSDART00000151779
ighv13-2
immunoglobulin heavy variable 13-2
chr7_+_58843700 0.05 ENSDART00000159500
ENSDART00000158436
lypla1
lysophospholipase I
chr25_+_26923193 0.04 ENSDART00000187364
grm8b
glutamate receptor, metabotropic 8b
chr22_+_15507218 0.04 ENSDART00000125450
gpc1a
glypican 1a
chr20_-_34868814 0.04 ENSDART00000153049
stmn4
stathmin-like 4
chr10_+_20628698 0.04 ENSDART00000064666
prnpb
prion protein b
chr8_-_22698651 0.04 ENSDART00000181411
iqsec2a
IQ motif and Sec7 domain 2a
chr13_-_39830999 0.04 ENSDART00000115089
zgc:171482
zgc:171482
chr11_+_19060278 0.04 ENSDART00000164294
magi1b
membrane associated guanylate kinase, WW and PDZ domain containing 1b
chr7_+_61050329 0.03 ENSDART00000115355
nwd2
NACHT and WD repeat domain containing 2
chr18_-_29925717 0.03 ENSDART00000099281
mhc2dbb
major histocompatibility complex class II DBB gene
chr7_-_72155022 0.03 ENSDART00000187984
zmp:0000001168
zmp:0000001168
chr18_+_15758375 0.03 ENSDART00000137554
si:ch211-219a15.4
si:ch211-219a15.4
chr4_-_5302162 0.02 ENSDART00000177099
SNAP91 (1 of many)
si:ch211-214j24.9
chr24_+_17007407 0.02 ENSDART00000110652
zfx
zinc finger protein, X-linked
chr11_+_13193747 0.02 ENSDART00000173336
si:dkey-9a6.4
si:dkey-9a6.4
chr13_+_31172833 0.02 ENSDART00000176378
CR931802.3

chr11_+_19060079 0.01 ENSDART00000158123
magi1b
membrane associated guanylate kinase, WW and PDZ domain containing 1b
chr18_+_20838786 0.01 ENSDART00000138692
ttc23
tetratricopeptide repeat domain 23
chr13_+_18545819 0.00 ENSDART00000101859
ENSDART00000110197
ENSDART00000136064
zgc:154058
zgc:154058
chr1_+_58442694 0.00 ENSDART00000160897
zgc:194906
zgc:194906

Network of associatons between targets according to the STRING database.

First level regulatory network of pou5f3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0008592 regulation of Toll signaling pathway(GO:0008592)
0.1 0.2 GO:0046104 deoxyribonucleoside metabolic process(GO:0009120) thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.1 0.5 GO:0046247 carotene metabolic process(GO:0016119) carotene catabolic process(GO:0016121) terpene metabolic process(GO:0042214) terpene catabolic process(GO:0046247)
0.0 0.7 GO:0045740 positive regulation of DNA replication(GO:0045740)
0.0 0.3 GO:0042407 cristae formation(GO:0042407)
0.0 0.2 GO:1901222 regulation of NIK/NF-kappaB signaling(GO:1901222)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.3 GO:0061617 MICOS complex(GO:0061617)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0003834 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.0 0.2 GO:0017113 uracil binding(GO:0002058) pyrimidine nucleobase binding(GO:0002061) dihydropyrimidine dehydrogenase (NADP+) activity(GO:0017113)
0.0 0.1 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha