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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for pou6f2

Z-value: 1.12

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Transcription factors associated with pou6f2

Gene Symbol Gene ID Gene Info
pou6f2
ENSDARG00000086362 POU class 6 homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
pou6f2dr11_v1_chr24_+_10039165_100391650.282.7e-01Click!

Activity profile of pou6f2 motif

Sorted Z-values of pou6f2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr8_-_23780334 5.28 ENSDART00000145179
ENSDART00000145894
zgc:195245
zgc:195245
chr2_-_15324837 4.66 ENSDART00000015655
tecrl2b
trans-2,3-enoyl-CoA reductase-like 2b
chr9_-_35633827 4.40 ENSDART00000077745
zp2l1
zona pellucida glycoprotein 2, like 1
chr20_-_6532462 3.43 ENSDART00000054653
mcm3l
MCM3 minichromosome maintenance deficient 3 (S. cerevisiae), like
chr4_+_9467049 3.41 ENSDART00000012659
zgc:55888
zgc:55888
chr21_-_13690712 3.35 ENSDART00000065817
pou5f3
POU domain, class 5, transcription factor 3
chr25_+_5972690 2.96 ENSDART00000067517
si:ch211-11i22.4
si:ch211-11i22.4
chr9_-_8314028 2.69 ENSDART00000102739
si:ch211-145c1.1
si:ch211-145c1.1
chr1_-_53468160 2.62 ENSDART00000143349
zgc:66455
zgc:66455
chr7_-_19364813 2.19 ENSDART00000173977
ntn4
netrin 4
chr11_-_34219211 1.76 ENSDART00000098472
tmem44
transmembrane protein 44
chr3_-_40054615 1.76 ENSDART00000003511
ENSDART00000102540
ENSDART00000146121
llgl1
lethal giant larvae homolog 1 (Drosophila)
chr3_-_55525627 1.71 ENSDART00000189234
tex2
testis expressed 2
chr12_+_17154655 1.69 ENSDART00000028003
ankrd22
ankyrin repeat domain 22
chr21_-_32060993 1.49 ENSDART00000131651
si:ch211-160j14.2
si:ch211-160j14.2
chr7_+_38717624 1.47 ENSDART00000132522
syt13
synaptotagmin XIII
chr5_+_54497730 1.37 ENSDART00000157722
tmem203
transmembrane protein 203
chr3_-_43356082 1.20 ENSDART00000171213
uncx
UNC homeobox
chr2_-_26596794 1.18 ENSDART00000134685
ENSDART00000056787
zgc:113691
zgc:113691
chr21_-_39177564 1.13 ENSDART00000065143
unc119b
unc-119 homolog b (C. elegans)
chr11_+_19433936 1.07 ENSDART00000162081
prickle2b
prickle homolog 2b
chr4_-_2380173 1.05 ENSDART00000177727
nap1l1
nucleosome assembly protein 1-like 1
chr20_-_37813863 1.03 ENSDART00000147529
batf3
basic leucine zipper transcription factor, ATF-like 3
chr20_+_33922339 0.99 ENSDART00000019059
lmx1a
LIM homeobox transcription factor 1, alpha
chr16_-_40426837 0.97 ENSDART00000193690
plekhf2
pleckstrin homology domain containing, family F (with FYVE domain) member 2
chr16_+_40043673 0.97 ENSDART00000102552
ENSDART00000125484
trmt11
tRNA methyltransferase 11 homolog (S. cerevisiae)
chr5_-_25733745 0.93 ENSDART00000051566
zgc:101016
zgc:101016
chr5_-_69934558 0.92 ENSDART00000124954
ugt2a4
UDP glucuronosyltransferase 2 family, polypeptide A4
chr15_-_33172246 0.91 ENSDART00000158666
nbeab
neurobeachin b
chr2_-_37312927 0.90 ENSDART00000141214
skila
SKI-like proto-oncogene a
chr8_-_21142550 0.89 ENSDART00000143192
ENSDART00000186820
ENSDART00000135938
cpt2
carnitine palmitoyltransferase 2
chr8_-_23776399 0.89 ENSDART00000114800
INAVA
si:ch211-163l21.4
chr5_+_25733774 0.88 ENSDART00000137088
ENSDART00000098467
abhd17b
abhydrolase domain containing 17B
chr2_+_38892631 0.88 ENSDART00000134040
si:ch211-119o8.4
si:ch211-119o8.4
chr19_+_15441022 0.86 ENSDART00000098970
ENSDART00000140276
lin28a
lin-28 homolog A (C. elegans)
chr18_-_38270430 0.78 ENSDART00000139519
caprin1b
cell cycle associated protein 1b
chr17_-_48705993 0.78 ENSDART00000030934
kcnk5a
potassium channel, subfamily K, member 5a
chr7_+_13988075 0.78 ENSDART00000186812
furina
furin (paired basic amino acid cleaving enzyme) a
chr13_+_38817871 0.76 ENSDART00000187708
col19a1
collagen, type XIX, alpha 1
chr7_+_38380135 0.74 ENSDART00000174005
rhpn2
rhophilin, Rho GTPase binding protein 2
chr20_+_29209767 0.73 ENSDART00000141252
katnbl1
katanin p80 subunit B-like 1
chr6_-_39198912 0.73 ENSDART00000077938
c1galt1b
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1b
chr22_-_21897203 0.72 ENSDART00000158501
ENSDART00000105566
ENSDART00000136795
gna11a
guanine nucleotide binding protein (G protein), alpha 11a (Gq class)
chr2_-_27619954 0.70 ENSDART00000144826
tgs1
trimethylguanosine synthase 1
chr12_+_27536270 0.70 ENSDART00000133719
etv4
ets variant 4
chr2_-_21819421 0.69 ENSDART00000121586
chd7
chromodomain helicase DNA binding protein 7
chr3_-_34561624 0.69 ENSDART00000129313
sept9a
septin 9a
chr22_-_354592 0.69 ENSDART00000155769
tmem240b
transmembrane protein 240b
chr20_+_29209926 0.68 ENSDART00000152949
ENSDART00000153016
katnbl1
katanin p80 subunit B-like 1
chr18_+_34181655 0.67 ENSDART00000130831
ENSDART00000109535
gmps
guanine monophosphate synthase
chr10_+_40284003 0.67 ENSDART00000062795
ENSDART00000193825
ENSDART00000113582
git2b
G protein-coupled receptor kinase interacting ArfGAP 2b
chr16_+_50741154 0.66 ENSDART00000101627
IGLON5
zgc:110372
chr14_-_31465905 0.63 ENSDART00000173108
gpc3
glypican 3
chr1_-_38171648 0.62 ENSDART00000137451
ENSDART00000047159
hmgb2a
high mobility group box 2a
chr12_+_32729470 0.60 ENSDART00000175712
rbfox3a
RNA binding fox-1 homolog 3a
chr11_-_43226255 0.59 ENSDART00000172929
sptbn1
spectrin, beta, non-erythrocytic 1
chr1_+_55755304 0.59 ENSDART00000144983
tecrb
trans-2,3-enoyl-CoA reductase b
chr7_+_53498152 0.59 ENSDART00000184497
znf609b
zinc finger protein 609b
chr7_+_31145386 0.58 ENSDART00000075407
ENSDART00000169462
fam189a1
family with sequence similarity 189, member A1
chr25_+_21716263 0.57 ENSDART00000148920
znf277
zinc finger protein 277
chr24_+_32411753 0.57 ENSDART00000058530
neurod6a
neuronal differentiation 6a
chr19_+_15440841 0.57 ENSDART00000182329
lin28a
lin-28 homolog A (C. elegans)
chr9_+_21793565 0.56 ENSDART00000134915
rev1
REV1, polymerase (DNA directed)
chr13_+_24552254 0.56 ENSDART00000147907
lgalslb
lectin, galactoside-binding-like b
chr9_+_38888025 0.55 ENSDART00000148306
map2
microtubule-associated protein 2
chr5_+_58455488 0.54 ENSDART00000038602
ENSDART00000127958
slc37a2
solute carrier family 37 (glucose-6-phosphate transporter), member 2
chr15_-_5720583 0.54 ENSDART00000158034
ENSDART00000190332
ENSDART00000109599
urb1
URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
chr1_-_34335752 0.53 ENSDART00000140157
si:dkey-24h22.5
si:dkey-24h22.5
chr3_-_61162750 0.53 ENSDART00000055064
pvalb8
parvalbumin 8
chr12_+_27536095 0.52 ENSDART00000013033
etv4
ets variant 4
chr24_-_16979728 0.52 ENSDART00000005331
klhl15
kelch-like family member 15
chr23_+_7548797 0.51 ENSDART00000006765
tm9sf4
transmembrane 9 superfamily protein member 4
chr2_+_29249204 0.50 ENSDART00000168957
cdh18a
cadherin 18, type 2a
chr8_-_4327473 0.50 ENSDART00000134378
cux2b
cut-like homeobox 2b
chr20_+_29209615 0.49 ENSDART00000062350
katnbl1
katanin p80 subunit B-like 1
chr25_+_28555584 0.49 ENSDART00000157046
SLC15A5
si:ch211-190o6.3
chr8_+_6576940 0.48 ENSDART00000138135
vsig8b
V-set and immunoglobulin domain containing 8b
chr16_-_40043322 0.47 ENSDART00000145278
si:dkey-29b11.3
si:dkey-29b11.3
chr16_-_26855936 0.47 ENSDART00000167320
ENSDART00000078119
ino80c
INO80 complex subunit C
chr16_+_25107344 0.47 ENSDART00000033211
zgc:66448
zgc:66448
chr12_-_35787801 0.46 ENSDART00000171682
aatkb
apoptosis-associated tyrosine kinase b
chr20_-_9436521 0.45 ENSDART00000133000
zgc:101840
zgc:101840
chr13_-_31017960 0.45 ENSDART00000145287
wdfy4
WDFY family member 4
chr4_+_5642696 0.45 ENSDART00000028941
mrps18a
mitochondrial ribosomal protein S18A
chr7_-_30174882 0.43 ENSDART00000110409
frmd5
FERM domain containing 5
chr14_+_11290828 0.42 ENSDART00000184078
rlim
ring finger protein, LIM domain interacting
chr25_-_20049449 0.42 ENSDART00000104315
zgc:136858
zgc:136858
chr14_-_26425416 0.41 ENSDART00000088690
lman2
lectin, mannose-binding 2
chr2_+_29249561 0.41 ENSDART00000099157
cdh18a
cadherin 18, type 2a
chr2_+_12302527 0.41 ENSDART00000091298
ENSDART00000182569
arhgap21b
Rho GTPase activating protein 21b
chr18_+_7283283 0.40 ENSDART00000141493
ANO2 (1 of many)
si:ch73-86n2.1
chr6_-_10740365 0.38 ENSDART00000150942
sp3b
Sp3b transcription factor
chr9_-_43538328 0.38 ENSDART00000140526
znf385b
zinc finger protein 385B
chr13_+_16279890 0.38 ENSDART00000101775
ENSDART00000057948
anxa11a
annexin A11a
chr7_+_36898850 0.37 ENSDART00000113342
tox3
TOX high mobility group box family member 3
chr19_+_8612839 0.35 ENSDART00000144925
snx27a
sorting nexin family member 27a
chr22_-_2959005 0.35 ENSDART00000040701
ing5a
inhibitor of growth family, member 5a
chr24_-_41267184 0.35 ENSDART00000063504
xylb
xylulokinase homolog (H. influenzae)
chr8_-_14080534 0.35 ENSDART00000042867
dedd
death effector domain containing
chr5_-_41638039 0.32 ENSDART00000144525
epg5
ectopic P-granules autophagy protein 5 homolog (C. elegans)
chr10_+_7593185 0.32 ENSDART00000162617
ENSDART00000162590
ENSDART00000171744
ppp2cb
protein phosphatase 2, catalytic subunit, beta isozyme
chr24_+_19415124 0.31 ENSDART00000186931
sulf1
sulfatase 1
chr13_+_1089942 0.31 ENSDART00000054322
cnrip1b
cannabinoid receptor interacting protein 1b
chr23_-_28423048 0.31 ENSDART00000140448
c1ql4a
complement component 1, q subcomponent-like 4
chr9_-_3934963 0.30 ENSDART00000062336
ubr3
ubiquitin protein ligase E3 component n-recognin 3
chr19_+_28256076 0.29 ENSDART00000133354
irx4b
iroquois homeobox 4b
chr5_-_26566435 0.28 ENSDART00000146070
arvcfb
ARVCF, delta catenin family member b
chr9_-_6624663 0.27 ENSDART00000092537
GPR45
si:dkeyp-118h3.5
chr13_+_3938526 0.27 ENSDART00000012759
yipf3
Yip1 domain family, member 3
chr18_-_40773413 0.27 ENSDART00000133797
vaspb
vasodilator stimulated phosphoprotein b
chr18_+_34362608 0.26 ENSDART00000131478
kcnab1a
potassium voltage-gated channel, shaker-related subfamily, beta member 1 a
chr11_-_31226578 0.26 ENSDART00000109698
nacc1b
nucleus accumbens associated 1, BEN and BTB (POZ) domain containing b
chr15_-_34930727 0.25 ENSDART00000179723
dhx16
DEAH (Asp-Glu-Ala-His) box polypeptide 16
chr23_-_25124783 0.25 ENSDART00000160278
idh3g
isocitrate dehydrogenase 3 (NAD+) gamma
chr11_+_41981959 0.25 ENSDART00000055707
her15.1
hairy and enhancer of split-related 15, tandem duplicate 1
chr18_-_43993614 0.25 ENSDART00000148535
ENSDART00000077357
bcl9l
B cell CLL/lymphoma 9-like
chr22_+_24215007 0.25 ENSDART00000162227
glrx2
glutaredoxin 2
chr14_+_3287740 0.24 ENSDART00000186290
cdx1a
caudal type homeobox 1a
chr19_-_32641725 0.24 ENSDART00000165006
ENSDART00000188185
hpca
hippocalcin
chr9_-_44953349 0.23 ENSDART00000135156
vil1
villin 1
chr17_+_51499789 0.23 ENSDART00000187701
CABZ01067581.1

chr4_-_16124417 0.23 ENSDART00000128079
ENSDART00000077664
atp2b1a
ATPase plasma membrane Ca2+ transporting 1a
chr5_+_23152282 0.23 ENSDART00000166783
tbx5b
T-box 5b
chr7_-_18416741 0.22 ENSDART00000097882
sstr1b
somatostatin receptor 1b
chr20_-_34663209 0.20 ENSDART00000132545
slc25a24
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
chr15_+_7057050 0.20 ENSDART00000061828
foxl2a
forkhead box L2a
chr15_+_24704798 0.20 ENSDART00000192470
LRRC75A
si:dkey-151p21.7
chr7_+_27976448 0.20 ENSDART00000181026
tub
tubby bipartite transcription factor
chr17_-_29902187 0.20 ENSDART00000009104
esrrb
estrogen-related receptor beta
chr13_-_3370638 0.20 ENSDART00000029649
prkn
parkin RBR E3 ubiquitin protein ligase
chr22_+_10698549 0.20 ENSDART00000081228
abhd14a
abhydrolase domain containing 14A
chr9_-_49493305 0.20 ENSDART00000148707
ENSDART00000148561
xirp2b
xin actin binding repeat containing 2b
chr4_+_3980247 0.20 ENSDART00000049194
gpr37b
G protein-coupled receptor 37b
chr9_-_38036984 0.20 ENSDART00000134574
hacd2
3-hydroxyacyl-CoA dehydratase 2
chr1_-_9123465 0.18 ENSDART00000081337
ndufab1a
NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1a
chr2_-_35566938 0.18 ENSDART00000029006
ENSDART00000077178
ENSDART00000125298
tnn
tenascin N
chr7_+_49862837 0.17 ENSDART00000174315
slc1a2a
solute carrier family 1 (glial high affinity glutamate transporter), member 2a
chr8_+_51050554 0.17 ENSDART00000166249
DISP3
si:dkey-32e23.6
chr22_-_30881738 0.17 ENSDART00000059965
si:dkey-49n23.1
si:dkey-49n23.1
chr2_+_10127762 0.17 ENSDART00000100726
insl5b
insulin-like 5b
chr1_-_57501299 0.17 ENSDART00000080600
zgc:171470
zgc:171470
chr12_-_3992839 0.17 ENSDART00000126100
si:ch211-136m16.8
si:ch211-136m16.8
chr1_+_50968908 0.16 ENSDART00000150353
ENSDART00000012842
mdh1aa
malate dehydrogenase 1Aa, NAD (soluble)
chr9_+_11034314 0.16 ENSDART00000032695
asic4a
acid-sensing (proton-gated) ion channel family member 4a
chr9_+_17982737 0.16 ENSDART00000192569
akap11
A kinase (PRKA) anchor protein 11
chr5_-_50641129 0.15 ENSDART00000190090
mctp1a
multiple C2 domains, transmembrane 1a
chr12_+_30367371 0.15 ENSDART00000153364
ccdc186
si:ch211-225b10.4
chr10_+_3507861 0.15 ENSDART00000092684
rph3aa
rabphilin 3A homolog (mouse), a
chr11_+_33628104 0.15 ENSDART00000165318
thsd7bb
thrombospondin, type I, domain containing 7Bb
chr17_-_50301313 0.15 ENSDART00000125772
si:ch73-50f9.4
si:ch73-50f9.4
chr11_+_20056732 0.14 ENSDART00000103997
fezf2
FEZ family zinc finger 2
chr15_-_38154616 0.14 ENSDART00000099392
irgq2
immunity-related GTPase family, q2
chr3_+_23738215 0.14 ENSDART00000143981
hoxb3a
homeobox B3a
chr10_-_9192450 0.14 ENSDART00000139783
si:dkeyp-41f9.4
si:dkeyp-41f9.4
chr12_-_20616160 0.14 ENSDART00000105362
snx11
sorting nexin 11
chr10_-_24391716 0.13 ENSDART00000141332
ENSDART00000100772
slc43a2b
solute carrier family 43 (amino acid system L transporter), member 2b
chr9_+_42063906 0.13 ENSDART00000048893
pcbp3
poly(rC) binding protein 3
chr13_+_25434932 0.13 ENSDART00000128562
si:dkey-51a16.9
si:dkey-51a16.9
chr24_-_6628359 0.13 ENSDART00000169731
arhgap21a
Rho GTPase activating protein 21a
chr20_+_13781779 0.13 ENSDART00000142999
ENSDART00000152471
lpgat1
lysophosphatidylglycerol acyltransferase 1
chr11_+_20057182 0.12 ENSDART00000184979
fezf2
FEZ family zinc finger 2
chr1_+_33634186 0.12 ENSDART00000075626
htr1fb
5-hydroxytryptamine (serotonin) receptor 1Fb
chr18_+_33276609 0.12 ENSDART00000137208
v2rx3
vomeronasal 2 receptor, x3
chr5_-_35953472 0.12 ENSDART00000143448
rxfp2l
relaxin/insulin-like family peptide receptor 2, like
chr6_+_43390387 0.12 ENSDART00000122793
mitfa
microphthalmia-associated transcription factor a
chr6_-_40713183 0.12 ENSDART00000157113
ENSDART00000154810
ENSDART00000153702
si:ch211-157b11.12
si:ch211-157b11.12
chr2_+_29842878 0.11 ENSDART00000131376
si:ch211-207d6.2
si:ch211-207d6.2
chr17_+_10094063 0.11 ENSDART00000168055
sec23a
Sec23 homolog A, COPII coat complex component
chr14_-_7207961 0.10 ENSDART00000167994
ENSDART00000166532
stox2b
storkhead box 2b
chr13_-_46200240 0.10 ENSDART00000056984
ftr69
finTRIM family, member 69
chr25_+_32755485 0.10 ENSDART00000162188
etfa
electron-transfer-flavoprotein, alpha polypeptide
chr3_-_30434016 0.10 ENSDART00000150958
lrrc4ba
leucine rich repeat containing 4Ba
chr4_-_16341801 0.10 ENSDART00000140190
kera
keratocan
chr12_+_30367079 0.10 ENSDART00000190112
ccdc186
si:ch211-225b10.4
chr21_-_26918901 0.10 ENSDART00000100685
lrfn4a
leucine rich repeat and fibronectin type III domain containing 4a
chr22_-_6444807 0.09 ENSDART00000188697
si:dkey-19a16.12
si:dkey-19a16.12
chr2_+_38370535 0.09 ENSDART00000179614
psmb11a
proteasome subunit beta 11a
chr21_+_25231160 0.09 ENSDART00000063089
ENSDART00000139127
gng8
guanine nucleotide binding protein (G protein), gamma 8
chr22_+_25814941 0.09 ENSDART00000161120
vasna
vasorin a
chr20_+_26394324 0.09 ENSDART00000078093
zbtb2b
zinc finger and BTB domain containing 2b
chr23_-_6660985 0.08 ENSDART00000162405
CR450824.2

chr13_+_18533005 0.08 ENSDART00000136024
ftr14l
finTRIM family, member 14-like
chr14_-_9713549 0.08 ENSDART00000193356
ENSDART00000166739
si:zfos-2326c3.2
si:zfos-2326c3.2
chr3_+_1107102 0.08 ENSDART00000092690
srebf2
sterol regulatory element binding transcription factor 2
chr20_-_18789543 0.08 ENSDART00000182240
ccm2
cerebral cavernous malformation 2
chr12_-_17698669 0.08 ENSDART00000191384
pvalb9
parvalbumin 9
chr9_-_19699728 0.08 ENSDART00000166780
si:ch211-141e20.2
si:ch211-141e20.2
chr8_+_21588067 0.07 ENSDART00000172190
ajap1
adherens junctions associated protein 1
chr18_-_19350792 0.07 ENSDART00000147902
megf11
multiple EGF-like-domains 11
chr1_-_11372456 0.07 ENSDART00000144164
ENSDART00000141238
sdk1b
sidekick cell adhesion molecule 1b
chr22_-_392224 0.07 ENSDART00000124720
CABZ01072989.1

chr14_-_32824380 0.06 ENSDART00000172791
ENSDART00000105745
inppl1b
inositol polyphosphate phosphatase-like 1b
chr7_-_27686021 0.06 ENSDART00000079112
ENSDART00000100989
calca
calcitonin/calcitonin-related polypeptide, alpha
chr12_-_17698517 0.06 ENSDART00000105974
pvalb9
parvalbumin 9
chr12_+_2648043 0.06 ENSDART00000082220
gdf2
growth differentiation factor 2
chr3_-_49110710 0.06 ENSDART00000160404
trim35-12
tripartite motif containing 35-12
chr22_+_2830703 0.05 ENSDART00000145463
ENSDART00000144785
si:dkey-20i20.8
si:dkey-20i20.8
chr23_+_21405201 0.05 ENSDART00000144409
iffo2a
intermediate filament family orphan 2a
chr19_-_5265155 0.05 ENSDART00000145003
prf1.3
perforin 1.3
chr9_-_44953664 0.05 ENSDART00000188558
ENSDART00000185210
vil1
villin 1

Network of associatons between targets according to the STRING database.

First level regulatory network of pou6f2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.4 GO:1902975 cell cycle DNA replication initiation(GO:1902292) nuclear cell cycle DNA replication initiation(GO:1902315) mitotic DNA replication initiation(GO:1902975)
0.3 3.1 GO:0043697 dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.2 0.5 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.2 0.5 GO:0090069 regulation of ribosome biogenesis(GO:0090069)
0.2 5.5 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.1 0.6 GO:0070987 error-free translesion synthesis(GO:0070987)
0.1 1.1 GO:0072584 caveolin-mediated endocytosis(GO:0072584) negative regulation of clathrin-mediated endocytosis(GO:1900186) regulation of caveolin-mediated endocytosis(GO:2001286) negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.1 1.8 GO:0032878 regulation of establishment or maintenance of cell polarity(GO:0032878)
0.1 2.6 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.3 GO:0005997 xylulose metabolic process(GO:0005997)
0.1 0.2 GO:0003214 cardiac left ventricle morphogenesis(GO:0003214) cardiac left ventricle formation(GO:0003218)
0.1 0.5 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.1 1.2 GO:0035108 limb morphogenesis(GO:0035108)
0.1 0.6 GO:0060976 coronary vasculature development(GO:0060976)
0.1 0.3 GO:2000392 lamellipodium morphogenesis(GO:0072673) regulation of lamellipodium morphogenesis(GO:2000392)
0.1 2.0 GO:0070831 basement membrane assembly(GO:0070831)
0.1 0.9 GO:0002084 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.1 0.2 GO:0048496 maintenance of organ identity(GO:0048496)
0.1 0.7 GO:0006177 GMP biosynthetic process(GO:0006177) GMP metabolic process(GO:0046037)
0.1 0.3 GO:1901017 negative regulation of potassium ion transmembrane transporter activity(GO:1901017) negative regulation of potassium ion transmembrane transport(GO:1901380) negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.1 0.3 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 0.8 GO:0060971 embryonic heart tube left/right pattern formation(GO:0060971)
0.1 0.7 GO:0048798 rRNA transcription(GO:0009303) swim bladder maturation(GO:0048796) swim bladder inflation(GO:0048798)
0.0 0.2 GO:0034505 tooth mineralization(GO:0034505)
0.0 0.3 GO:0021767 mammillary body development(GO:0021767)
0.0 1.1 GO:1903845 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.0 0.3 GO:0021910 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910) regulation of myotome development(GO:2000290)
0.0 0.3 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.0 1.2 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.3 GO:2000272 negative regulation of receptor activity(GO:2000272)
0.0 0.7 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.1 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.0 0.2 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.0 0.3 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.8 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 1.1 GO:0001878 response to yeast(GO:0001878)
0.0 0.9 GO:0014059 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 1.0 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.0 0.4 GO:0017015 regulation of transforming growth factor beta receptor signaling pathway(GO:0017015) regulation of cellular response to transforming growth factor beta stimulus(GO:1903844)
0.0 0.2 GO:1900407 regulation of cellular response to oxidative stress(GO:1900407)
0.0 0.3 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)
0.0 0.3 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.0 0.4 GO:0032506 cytokinetic process(GO:0032506)
0.0 0.2 GO:0071384 cellular response to corticosteroid stimulus(GO:0071384) cellular response to glucocorticoid stimulus(GO:0071385)
0.0 0.5 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.0 GO:0060631 regulation of meiosis I(GO:0060631)
0.0 0.6 GO:0051693 actin filament capping(GO:0051693)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.4 GO:0042555 MCM complex(GO:0042555)
0.1 0.6 GO:0008091 spectrin(GO:0008091)
0.1 1.1 GO:0045171 intercellular bridge(GO:0045171)
0.1 2.0 GO:0043256 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.1 0.3 GO:0032433 filopodium tip(GO:0032433)
0.0 1.8 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.5 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.6 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.1 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.0 0.4 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.3 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.3 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.5 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.9 GO:0016342 catenin complex(GO:0016342)
0.0 1.0 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.2 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 0.4 GO:0031105 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.8 GO:0030173 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.8 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.2 1.0 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.2 0.5 GO:0061513 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.1 3.4 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 0.9 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.1 1.8 GO:0045159 myosin II binding(GO:0045159)
0.1 0.7 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.1 5.3 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)
0.1 0.4 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.1 0.2 GO:0000035 acyl binding(GO:0000035)
0.1 0.3 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.2 GO:0004362 glutathione-disulfide reductase activity(GO:0004362)
0.0 0.2 GO:0102345 3-hydroxyacyl-CoA dehydratase activity(GO:0018812) 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.0 0.7 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0 0.9 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.6 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.2 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.0 0.4 GO:0005537 mannose binding(GO:0005537)
0.0 0.8 GO:0022840 leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.0 0.2 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 0.3 GO:0005522 profilin binding(GO:0005522)
0.0 0.6 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.3 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.9 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.9 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 3.2 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 0.3 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.0 0.2 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.9 GO:0046332 SMAD binding(GO:0046332)
0.0 0.3 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.0 3.2 GO:0030246 carbohydrate binding(GO:0030246)
0.0 1.2 GO:0045296 cadherin binding(GO:0045296)
0.0 0.3 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.2 GO:0031267 small GTPase binding(GO:0031267)
0.0 0.6 GO:0005200 structural constituent of cytoskeleton(GO:0005200)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 2.2 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 1.8 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.8 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.7 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.9 PID TGFBR PATHWAY TGF-beta receptor signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.2 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.1 0.9 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.7 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.6 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.6 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.7 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.3 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 0.1 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.8 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.3 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)