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PRJNA438478: RNAseq of wild type zebrafish germline
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Results for pou6f2
Z-value: 1.12
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Transcription factors associated with pou6f2
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| pou6f2 | dr11_v1_chr24_+_10039165_10039165 | 0.28 | 2.7e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr8_-_23780334 Show fit | 5.28 |
ENSDART00000145179
ENSDART00000145894 |
zgc:195245 |
|
| chr2_-_15324837 Show fit | 4.66 |
ENSDART00000015655
|
trans-2,3-enoyl-CoA reductase-like 2b |
|
| chr9_-_35633827 Show fit | 4.40 |
ENSDART00000077745
|
zona pellucida glycoprotein 2, like 1 |
|
| chr20_-_6532462 Show fit | 3.43 |
ENSDART00000054653
|
MCM3 minichromosome maintenance deficient 3 (S. cerevisiae), like |
|
| chr4_+_9467049 Show fit | 3.41 |
ENSDART00000012659
|
zgc:55888 |
|
| chr21_-_13690712 Show fit | 3.35 |
ENSDART00000065817
|
POU domain, class 5, transcription factor 3 |
|
| chr25_+_5972690 Show fit | 2.96 |
ENSDART00000067517
|
si:ch211-11i22.4 |
|
| chr9_-_8314028 Show fit | 2.69 |
ENSDART00000102739
|
si:ch211-145c1.1 |
|
| chr1_-_53468160 Show fit | 2.62 |
ENSDART00000143349
|
zgc:66455 |
|
| chr7_-_19364813 Show fit | 2.19 |
ENSDART00000173977
|
netrin 4 |
Network of associatons between targets according to the STRING database.
First level regulatory network of pou6f2
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 5.5 | GO:0042761 | very long-chain fatty acid biosynthetic process(GO:0042761) |
| 0.5 | 3.4 | GO:1902975 | cell cycle DNA replication initiation(GO:1902292) nuclear cell cycle DNA replication initiation(GO:1902315) mitotic DNA replication initiation(GO:1902975) |
| 0.3 | 3.1 | GO:0043697 | dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697) |
| 0.1 | 2.6 | GO:0048251 | elastic fiber assembly(GO:0048251) |
| 0.1 | 2.0 | GO:0070831 | basement membrane assembly(GO:0070831) |
| 0.1 | 1.8 | GO:0032878 | regulation of establishment or maintenance of cell polarity(GO:0032878) |
| 0.1 | 1.2 | GO:0035108 | limb morphogenesis(GO:0035108) |
| 0.0 | 1.2 | GO:0016339 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339) |
| 0.1 | 1.1 | GO:0072584 | caveolin-mediated endocytosis(GO:0072584) negative regulation of clathrin-mediated endocytosis(GO:1900186) regulation of caveolin-mediated endocytosis(GO:2001286) negative regulation of caveolin-mediated endocytosis(GO:2001287) |
| 0.0 | 1.1 | GO:1903845 | negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 3.4 | GO:0042555 | MCM complex(GO:0042555) |
| 0.1 | 2.0 | GO:0043256 | basal lamina(GO:0005605) laminin complex(GO:0043256) |
| 0.0 | 1.8 | GO:0030864 | cortical actin cytoskeleton(GO:0030864) |
| 0.1 | 1.1 | GO:0045171 | intercellular bridge(GO:0045171) |
| 0.0 | 1.0 | GO:0031901 | early endosome membrane(GO:0031901) |
| 0.0 | 0.9 | GO:0016342 | catenin complex(GO:0016342) |
| 0.0 | 0.8 | GO:0030173 | integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228) |
| 0.1 | 0.6 | GO:0008091 | spectrin(GO:0008091) |
| 0.0 | 0.6 | GO:0046658 | anchored component of plasma membrane(GO:0046658) |
| 0.0 | 0.5 | GO:0033202 | Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 5.3 | GO:0016627 | oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627) |
| 0.1 | 3.4 | GO:0003688 | DNA replication origin binding(GO:0003688) |
| 0.0 | 3.2 | GO:0046982 | protein heterodimerization activity(GO:0046982) |
| 0.0 | 3.2 | GO:0030246 | carbohydrate binding(GO:0030246) |
| 0.3 | 1.8 | GO:0015189 | L-lysine transmembrane transporter activity(GO:0015189) |
| 0.1 | 1.8 | GO:0045159 | myosin II binding(GO:0045159) |
| 0.0 | 1.2 | GO:0045296 | cadherin binding(GO:0045296) |
| 0.2 | 1.0 | GO:0004809 | tRNA (guanine-N2-)-methyltransferase activity(GO:0004809) |
| 0.1 | 0.9 | GO:0004095 | carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416) |
| 0.0 | 0.9 | GO:0098599 | palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.2 | NABA BASEMENT MEMBRANES | Genes encoding structural components of basement membranes |
| 0.0 | 1.8 | PID LKB1 PATHWAY | LKB1 signaling events |
| 0.1 | 1.0 | PID TCR CALCIUM PATHWAY | Calcium signaling in the CD4+ TCR pathway |
| 0.0 | 0.9 | PID TGFBR PATHWAY | TGF-beta receptor signaling |
| 0.0 | 0.8 | NABA COLLAGENS | Genes encoding collagen proteins |
| 0.0 | 0.7 | PID WNT NONCANONICAL PATHWAY | Noncanonical Wnt signaling pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 2.2 | REACTOME NETRIN1 SIGNALING | Genes involved in Netrin-1 signaling |
| 0.1 | 0.9 | REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE | Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle |
| 0.0 | 0.8 | REACTOME COLLAGEN FORMATION | Genes involved in Collagen formation |
| 0.0 | 0.7 | REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS | Genes involved in Purine ribonucleoside monophosphate biosynthesis |
| 0.0 | 0.7 | REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION | Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression |
| 0.0 | 0.6 | REACTOME HS GAG BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
| 0.0 | 0.6 | REACTOME INTERACTION BETWEEN L1 AND ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 0.0 | 0.3 | REACTOME CTLA4 INHIBITORY SIGNALING | Genes involved in CTLA4 inhibitory signaling |
| 0.0 | 0.3 | REACTOME CITRIC ACID CYCLE TCA CYCLE | Genes involved in Citric acid cycle (TCA cycle) |
| 0.0 | 0.1 | REACTOME ACYL CHAIN REMODELLING OF PG | Genes involved in Acyl chain remodelling of PG |