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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for prdm1a

Z-value: 0.45

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Transcription factors associated with prdm1a

Gene Symbol Gene ID Gene Info
prdm1a
ENSDARG00000002445 PR domain containing 1a, with ZNF domain

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
prdm1adr11_v1_chr16_-_7443388_74433880.953.3e-09Click!

Activity profile of prdm1a motif

Sorted Z-values of prdm1a motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr24_+_24923166 1.38 ENSDART00000065288
pcyt1ba
phosphate cytidylyltransferase 1, choline, beta a
chr8_-_50259448 1.29 ENSDART00000146056
nkx3-1
NK3 homeobox 1
chr10_-_29816467 1.19 ENSDART00000055913
hist2h2l
histone 2, H2, like
chr14_+_45566074 1.16 ENSDART00000133477
ENSDART00000185899
zgc:92249
zgc:92249
chr16_+_42829735 1.15 ENSDART00000014956
polr3glb
polymerase (RNA) III (DNA directed) polypeptide G like b
chr6_+_24661736 1.14 ENSDART00000169283
znf644b
zinc finger protein 644b
chr4_+_686157 1.08 ENSDART00000169748
fbxo7
F-box protein 7
chr24_-_39610585 1.06 ENSDART00000066506
cox6b1
cytochrome c oxidase subunit VIb polypeptide 1
chr10_-_34981219 0.97 ENSDART00000132823
smad9
SMAD family member 9
chr10_-_34981028 0.97 ENSDART00000186108
smad9
SMAD family member 9
chr15_-_47929455 0.96 ENSDART00000064462
psma6l
proteasome subunit alpha 6, like
chr25_+_245438 0.93 ENSDART00000004689
zgc:92481
zgc:92481
chr16_+_42830152 0.93 ENSDART00000159730
polr3glb
polymerase (RNA) III (DNA directed) polypeptide G like b
chr7_-_28148310 0.93 ENSDART00000044208
lmo1
LIM domain only 1
chr24_+_12945803 0.91 ENSDART00000005105
psme1
proteasome activator subunit 1
chr7_+_49695904 0.87 ENSDART00000183550
ENSDART00000126991
ascl1b
achaete-scute family bHLH transcription factor 1b
chr3_-_12026741 0.80 ENSDART00000132238
cfap70
cilia and flagella associated protein 70
chr19_-_7115229 0.76 ENSDART00000001930
psmb13a
proteasome subunit beta 13a
chr11_-_18705303 0.75 ENSDART00000059732
id1
inhibitor of DNA binding 1
chr7_+_65673885 0.74 ENSDART00000169182
parvab
parvin, alpha b
chr25_+_245018 0.74 ENSDART00000155344
zgc:92481
zgc:92481
chr11_-_38492269 0.69 ENSDART00000065613
elk4
ELK4, ETS-domain protein
chr11_-_38492564 0.69 ENSDART00000102850
elk4
ELK4, ETS-domain protein
chr1_-_44710937 0.67 ENSDART00000139036
si:dkey-28b4.7
si:dkey-28b4.7
chr6_-_7718200 0.66 ENSDART00000189664
ENSDART00000114282
rpsa
ribosomal protein SA
chr19_+_7115223 0.65 ENSDART00000001359
psmb12
proteasome subunit beta 12
chr18_-_18543358 0.62 ENSDART00000126460
il34
interleukin 34
chr8_+_16004551 0.58 ENSDART00000165141
elavl4
ELAV like neuron-specific RNA binding protein 4
chr23_-_30787932 0.58 ENSDART00000135771
myt1a
myelin transcription factor 1a
chr4_+_25558849 0.52 ENSDART00000113663
ENSDART00000100755
ENSDART00000111416
ENSDART00000127840
ENSDART00000168618
ENSDART00000111820
ENSDART00000113866
ENSDART00000110107
ENSDART00000111344
ENSDART00000108548
zgc:195175
zgc:195175
chr11_-_29623380 0.52 ENSDART00000162587
ENSDART00000193935
ENSDART00000191646
chd5
chromodomain helicase DNA binding protein 5
chr14_-_4121052 0.51 ENSDART00000167074
irf2
interferon regulatory factor 2
chr12_+_5189776 0.51 ENSDART00000081298
lgi1b
leucine-rich, glioma inactivated 1b
chr3_+_24618012 0.50 ENSDART00000111997
zgc:171506
zgc:171506
chr5_+_59494079 0.50 ENSDART00000148727
gtf2ird1
GTF2I repeat domain containing 1
chr11_-_34628789 0.48 ENSDART00000192433
mapkapk3
mitogen-activated protein kinase-activated protein kinase 3
chr16_-_9802449 0.47 ENSDART00000081208
tapbpl
TAP binding protein (tapasin)-like
chr23_+_642001 0.46 ENSDART00000030643
ENSDART00000124850
irf10
interferon regulatory factor 10
chr16_-_51271962 0.46 ENSDART00000164021
ENSDART00000046420
serpinb1l1
serpin peptidase inhibitor, clade B (ovalbumin), member 1, like 1
chr19_+_12350069 0.45 ENSDART00000052240
psmg2
proteasome (prosome, macropain) assembly chaperone 2
chr12_+_20641102 0.45 ENSDART00000152964
calcoco2
calcium binding and coiled-coil domain 2
chr16_-_9802998 0.44 ENSDART00000154217
tapbpl
TAP binding protein (tapasin)-like
chr25_+_4979446 0.41 ENSDART00000154131
ENSDART00000155537
si:ch73-265h17.1
si:ch73-265h17.1
chr10_+_10210455 0.41 ENSDART00000144214
sh2d3ca
SH2 domain containing 3Ca
chr1_-_45636362 0.39 ENSDART00000181757
sept3
septin 3
chr2_+_33051730 0.39 ENSDART00000177902
ENSDART00000187903
rnf220a
ring finger protein 220a
chr22_+_1683185 0.38 ENSDART00000158109
si:dkey-1b17.6
si:dkey-1b17.6
chr16_-_43344859 0.37 ENSDART00000058680
psma2
proteasome subunit alpha 2
chr22_-_18164671 0.37 ENSDART00000014057
rfxank
regulatory factor X-associated ankyrin-containing protein
chr7_+_11197940 0.37 ENSDART00000081346
cemip
cell migration inducing protein, hyaluronan binding
chr14_+_35806605 0.36 ENSDART00000173093
gria2b
glutamate receptor, ionotropic, AMPA 2b
chr1_+_31942961 0.36 ENSDART00000007522
anos1a
anosmin 1a
chr23_+_642395 0.36 ENSDART00000186995
irf10
interferon regulatory factor 10
chr2_-_19520324 0.35 ENSDART00000079877
pimr52
Pim proto-oncogene, serine/threonine kinase, related 52
chr13_-_1151410 0.35 ENSDART00000007231
psmb1
proteasome subunit beta 1
chr14_-_4120636 0.34 ENSDART00000059230
irf2
interferon regulatory factor 2
chr3_+_59935606 0.34 ENSDART00000154157
arhgdia
Rho GDP dissociation inhibitor (GDI) alpha
chr16_+_43344475 0.33 ENSDART00000085282
mrpl32
mitochondrial ribosomal protein L32
chr4_-_77216726 0.32 ENSDART00000099943
psmb10
proteasome subunit beta 10
chr2_-_16254782 0.32 ENSDART00000133708
arhgef4
Rho guanine nucleotide exchange factor (GEF) 4
chr18_+_14693682 0.32 ENSDART00000132249
uri1
URI1, prefoldin-like chaperone
chr4_-_20208166 0.32 ENSDART00000066891
gsap
gamma-secretase activating protein
chr2_-_24369087 0.32 ENSDART00000081237
plvapa
plasmalemma vesicle associated protein a
chr20_+_47434709 0.32 ENSDART00000067776
rab10
RAB10, member RAS oncogene family
chr4_-_74367912 0.32 ENSDART00000174199
ENSDART00000165257
ptprb
protein tyrosine phosphatase, receptor type, b
chr5_+_51443009 0.31 ENSDART00000083350
rasgrf2b
Ras protein-specific guanine nucleotide-releasing factor 2b
chr17_+_25955003 0.31 ENSDART00000156029
grid1a
glutamate receptor, ionotropic, delta 1a
chr1_-_7603734 0.30 ENSDART00000009315
mxb
myxovirus (influenza) resistance B
chr21_+_5636008 0.30 ENSDART00000158385
shroom3
shroom family member 3
chr9_-_8454060 0.29 ENSDART00000110158
irs2b
insulin receptor substrate 2b
chr2_+_21486529 0.29 ENSDART00000047468
inhbab
inhibin, beta Ab
chr5_+_13373593 0.29 ENSDART00000051668
ENSDART00000183883
ccl19a.2
chemokine (C-C motif) ligand 19a, tandem duplicate 2
chr11_-_36350421 0.29 ENSDART00000141477
psma5
proteasome subunit alpha 5
chr10_+_28587446 0.29 ENSDART00000030138
ENSDART00000137508
cblb
Cbl proto-oncogene B, E3 ubiquitin protein ligase
chr7_-_37563883 0.28 ENSDART00000148805
nod2
nucleotide-binding oligomerization domain containing 2
chr8_+_39998467 0.28 ENSDART00000073782
ENSDART00000134452
ggt5a
gamma-glutamyltransferase 5a
chr7_+_48870496 0.28 ENSDART00000009642
igf2a
insulin-like growth factor 2a
chr21_+_5169154 0.27 ENSDART00000102559
zgc:122979
zgc:122979
chr5_-_43935460 0.25 ENSDART00000166152
ENSDART00000188969
si:ch211-204c21.1
si:ch211-204c21.1
chr1_+_31706668 0.24 ENSDART00000057879
as3mt
arsenite methyltransferase
chr22_-_18164835 0.24 ENSDART00000143189
rfxank
regulatory factor X-associated ankyrin-containing protein
chr2_+_33052169 0.23 ENSDART00000180008
rnf220a
ring finger protein 220a
chr22_-_23748284 0.23 ENSDART00000162005
cfhl2
complement factor H like 2
chr21_-_7781555 0.22 ENSDART00000084380
ENSDART00000189131
aggf1
angiogenic factor with G patch and FHA domains 1
chr7_+_36552725 0.22 ENSDART00000173682
chd9
chromodomain helicase DNA binding protein 9
chr20_-_20402500 0.22 ENSDART00000190747
ENSDART00000185065
prkchb
protein kinase C, eta, b
chr16_-_50181206 0.21 ENSDART00000148478
lim2.5
lens intrinsic membrane protein 2.5
chr11_+_21910752 0.21 ENSDART00000114288
foxp4
forkhead box P4
chr1_+_59154521 0.21 ENSDART00000130089
ENSDART00000152456
soul5l
heme-binding protein soul5, like
chr3_+_1942219 0.21 ENSDART00000114520
zgc:165583
zgc:165583
chr7_-_8881514 0.21 ENSDART00000081620
vax2
ventral anterior homeobox 2
chr16_+_5408748 0.21 ENSDART00000160008
ENSDART00000014024
plecb
plectin b
chr1_-_54938137 0.21 ENSDART00000147212
crtac1a
cartilage acidic protein 1a
chr4_+_34417403 0.21 ENSDART00000186032
ENSDART00000167909
si:ch211-246b8.2
si:ch211-246b8.2
chr4_-_76370630 0.20 ENSDART00000168831
ENSDART00000174313
si:ch73-158p21.3
si:ch73-158p21.3
chr23_+_33718602 0.20 ENSDART00000024695
dazap2
DAZ associated protein 2
chr12_+_17042754 0.20 ENSDART00000066439
ch25h
cholesterol 25-hydroxylase
chr25_+_8955530 0.20 ENSDART00000156444
si:ch211-256a21.4
si:ch211-256a21.4
chr17_+_45404758 0.19 ENSDART00000147557
tagapa
T cell activation RhoGTPase activating protein a
chr5_-_41645058 0.19 ENSDART00000051092
riok2
RIO kinase 2 (yeast)
chr8_+_16004154 0.19 ENSDART00000134787
ENSDART00000172510
ENSDART00000141173
elavl4
ELAV like neuron-specific RNA binding protein 4
chr6_-_10780698 0.19 ENSDART00000151714
gpr155b
G protein-coupled receptor 155b
chr13_-_43637371 0.18 ENSDART00000127930
ENSDART00000084474
fam160b1
family with sequence similarity 160, member B1
chr3_+_47322494 0.18 ENSDART00000102202
ppap2d
phosphatidic acid phosphatase type 2D
chr20_-_26929685 0.17 ENSDART00000132556
ftr79
finTRIM family, member 79
chr23_-_37835794 0.17 ENSDART00000137358
cd40
CD40 molecule, TNF receptor superfamily member 5
chr4_+_17524330 0.17 ENSDART00000172169
ENSDART00000021610
recql
RecQ helicase-like
chr4_+_5132951 0.17 ENSDART00000103279
ccnd2b
cyclin D2, b
chr16_+_13855039 0.16 ENSDART00000113764
ENSDART00000143983
zgc:174888
zgc:174888
chr2_+_30969029 0.16 ENSDART00000085242
lpin2
lipin 2
chr16_-_31686602 0.16 ENSDART00000170357
c1s
complement component 1, s subcomponent
chr6_-_39313027 0.16 ENSDART00000012644
krt4
keratin 4
chr1_+_53377432 0.15 ENSDART00000177581
ucp1
uncoupling protein 1
chr5_-_42904329 0.15 ENSDART00000112807
cxcl20
chemokine (C-X-C motif) ligand 20
chr1_-_21599219 0.14 ENSDART00000148327
adamtsl7
ADAMTS-like 7
chr6_-_8580857 0.14 ENSDART00000138858
ENSDART00000041142
myh11a
myosin, heavy chain 11a, smooth muscle
chr4_-_6373735 0.14 ENSDART00000140100
MDFIC
si:ch73-156e19.1
chr10_+_17776981 0.13 ENSDART00000141693
ccl19b
chemokine (C-C motif) ligand 19b
chr23_-_3703569 0.13 ENSDART00000143731
pacsin1a
protein kinase C and casein kinase substrate in neurons 1a
chr15_-_41438821 0.13 ENSDART00000136952
nlrc8
NLR family CARD domain containing 8
chr21_-_20711739 0.13 ENSDART00000190918
BX530077.1

chr16_-_25535430 0.13 ENSDART00000077420
dtnbp1a
dystrobrevin binding protein 1a
chr22_-_23668356 0.12 ENSDART00000167106
ENSDART00000159622
ENSDART00000163228
cfh
complement factor H
chr11_-_44484952 0.12 ENSDART00000166674
ENSDART00000188016
mfn1b
mitofusin 1b
chr2_+_38608290 0.12 ENSDART00000159066
cdh24b
cadherin 24, type 2b
chr20_-_25412181 0.12 ENSDART00000062780
itsn2a
intersectin 2a
chr11_-_44485700 0.12 ENSDART00000186613
ENSDART00000172828
ENSDART00000113222
mfn1b
mitofusin 1b
chr3_-_7974028 0.12 ENSDART00000144459
trim35-22
tripartite motif containing 35-22
chr11_-_21528056 0.12 ENSDART00000181626
srgap2
SLIT-ROBO Rho GTPase activating protein 2
chr15_+_17752928 0.12 ENSDART00000155314
si:ch211-213d14.2
si:ch211-213d14.2
chr21_+_30306369 0.12 ENSDART00000145050
ENSDART00000059420
lcp2a
lymphocyte cytosolic protein 2a
chr12_+_20641471 0.11 ENSDART00000133654
calcoco2
calcium binding and coiled-coil domain 2
chr13_+_30912117 0.11 ENSDART00000133138
drgx
dorsal root ganglia homeobox
chr20_+_4793516 0.11 ENSDART00000053875
lgals8a
galectin 8a
chr11_-_26040594 0.11 ENSDART00000144115
kaznb
kazrin, periplakin interacting protein b
chr23_-_6982966 0.11 ENSDART00000033774
ENSDART00000169965
edem2
ER degradation enhancer, mannosidase alpha-like 2
chr1_+_20069535 0.10 ENSDART00000088653
prss12
protease, serine, 12 (neurotrypsin, motopsin)
chr13_+_30912385 0.10 ENSDART00000182642
drgx
dorsal root ganglia homeobox
chr5_+_32007627 0.10 ENSDART00000183061
scai
suppressor of cancer cell invasion
chr20_-_26936887 0.10 ENSDART00000160827
ftr79
finTRIM family, member 79
chr4_+_35130120 0.10 ENSDART00000192362
ENSDART00000181204
si:dkey-279j5.1
si:dkey-279j5.1
chr7_-_3693536 0.10 ENSDART00000126381
si:ch211-282j17.13
si:ch211-282j17.13
chr4_+_38550788 0.08 ENSDART00000157412
si:ch211-209n20.1
si:ch211-209n20.1
chr17_-_19784035 0.08 ENSDART00000190209
fmn2a
formin 2a
chr8_-_17980317 0.08 ENSDART00000129148
tnni3k
TNNI3 interacting kinase
chr20_-_26383368 0.08 ENSDART00000024518
ENSDART00000087844
esr1
estrogen receptor 1
chr12_-_16380593 0.08 ENSDART00000152133
hectd2
HECT domain containing 2
chr19_+_23296616 0.08 ENSDART00000134567
irgf1
immunity-related GTPase family, f1
chr4_+_43522680 0.08 ENSDART00000182252
si:dkeyp-53e4.4
si:dkeyp-53e4.4
chr5_-_38197080 0.08 ENSDART00000140708
si:ch211-284e13.9
si:ch211-284e13.9
chr3_-_11040575 0.07 ENSDART00000159802
CR382337.2

chr5_-_43935119 0.07 ENSDART00000142271
si:ch211-204c21.1
si:ch211-204c21.1
chr17_+_39242437 0.07 ENSDART00000156138
ENSDART00000128863
zgc:174356
zgc:174356
chr9_+_33267211 0.07 ENSDART00000025635
usp9
ubiquitin specific peptidase 9
chr4_-_71177920 0.07 ENSDART00000158287
si:dkey-193i10.1
si:dkey-193i10.1
chr1_+_44710955 0.07 ENSDART00000131296
ENSDART00000142187
ssrp1b
structure specific recognition protein 1b
chr5_-_46980651 0.07 ENSDART00000181022
ENSDART00000168038
edil3a
EGF-like repeats and discoidin I-like domains 3a
chr16_-_9383629 0.07 ENSDART00000084264
ENSDART00000166958
adcy2a
adenylate cyclase 2a
chr5_+_21211135 0.06 ENSDART00000088492
bmp10
bone morphogenetic protein 10
chr20_+_4793790 0.06 ENSDART00000153486
lgals8a
galectin 8a
chr24_-_20915050 0.06 ENSDART00000133763
si:ch211-161h7.5
si:ch211-161h7.5
chr7_+_26167420 0.06 ENSDART00000173941
si:ch211-196f2.6
si:ch211-196f2.6
chr12_-_4028079 0.06 ENSDART00000128676
si:ch211-180a12.2
si:ch211-180a12.2
chr2_-_43850637 0.06 ENSDART00000136077
zeb1a
zinc finger E-box binding homeobox 1a
chr12_-_16380242 0.06 ENSDART00000168105
hectd2
HECT domain containing 2
chr9_-_15208129 0.06 ENSDART00000137043
ENSDART00000131512
pard3bb
par-3 family cell polarity regulator beta b
chr23_-_27123171 0.05 ENSDART00000023218
ENSDART00000146467
stat6
signal transducer and activator of transcription 6, interleukin-4 induced
chr11_+_37144328 0.05 ENSDART00000162830
wnk2
WNK lysine deficient protein kinase 2
chr3_+_39663987 0.05 ENSDART00000184614
ENSDART00000184573
ENSDART00000183127
epn2
epsin 2
chr8_-_24135171 0.05 ENSDART00000112926
adora1b
adenosine A1 receptor b
chr5_-_50781623 0.05 ENSDART00000114950
zgc:194908
zgc:194908
chr5_+_45895791 0.05 ENSDART00000141039
polk
polymerase (DNA directed) kappa
chr18_-_16792561 0.05 ENSDART00000145546
ampd3b
adenosine monophosphate deaminase 3b
chr6_-_58149165 0.05 ENSDART00000170752
tox2
TOX high mobility group box family member 2
chr4_+_1461079 0.05 ENSDART00000082383
trim35-14
tripartite motif containing 35-14
chr22_+_36719821 0.04 ENSDART00000149093
TRIM35 (1 of many)
si:ch1073-324l1.1
chr21_-_31143903 0.04 ENSDART00000111571
rap1gap2b
RAP1 GTPase activating protein 2b
chr19_+_2275019 0.04 ENSDART00000136138
itgb8
integrin, beta 8
chr3_-_8035737 0.04 ENSDART00000170642
trim35-19
tripartite motif containing 35-19
chr1_+_57787642 0.04 ENSDART00000127091
si:dkey-1c7.2
si:dkey-1c7.2
chr24_+_24285751 0.04 ENSDART00000122294
ythdf3
YTH N(6)-methyladenosine RNA binding protein 3
chr4_-_22338906 0.03 ENSDART00000131402
golgb1
golgin B1
chr8_+_39570615 0.03 ENSDART00000142557
lzts1
leucine zipper, putative tumor suppressor 1
chr22_+_19230434 0.03 ENSDART00000132929
si:dkey-21e2.8
si:dkey-21e2.8
chr7_+_17456686 0.03 ENSDART00000113472
nitr1b
novel immune-type receptor 1b
chr19_+_18739085 0.03 ENSDART00000188868
spaca4l
sperm acrosome associated 4 like
chr4_-_37696010 0.03 ENSDART00000169984
si:dkey-3p4.1
si:dkey-3p4.1
chr13_+_21804058 0.03 ENSDART00000140307
si:ch211-51a6.2
si:ch211-51a6.2
chr19_-_10971230 0.03 ENSDART00000166196
LO018584.1

chr12_-_44070043 0.03 ENSDART00000180059
si:ch73-329n5.3
si:ch73-329n5.3
chr1_-_8966046 0.03 ENSDART00000136198
socs1b
suppressor of cytokine signaling 1b
chr5_-_30176349 0.03 ENSDART00000186584
adamts8a
ADAM metallopeptidase with thrombospondin type 1 motif, 8a
chr4_-_32466676 0.03 ENSDART00000193347
ENSDART00000169396
ENSDART00000145784
si:dkey-16p6.1
si:dkey-16p6.1
chr22_+_1508545 0.03 ENSDART00000164814
zgc:173486
zgc:173486
chr4_+_70791887 0.02 ENSDART00000164234
si:ch211-127b6.2
si:ch211-127b6.2
chr5_-_64103863 0.02 ENSDART00000135014
ENSDART00000083684
pappab
pregnancy-associated plasma protein A, pappalysin 1b
chr5_-_44286987 0.02 ENSDART00000184112
si:ch73-337l15.2
si:ch73-337l15.2
chr14_+_21754521 0.02 ENSDART00000111839
kdm2ab
lysine (K)-specific demethylase 2Ab
chr4_-_46948863 0.02 ENSDART00000168835
si:dkey-16p6.1
si:dkey-16p6.1
chr22_-_10019768 0.02 ENSDART00000162077
BX324216.2

Network of associatons between targets according to the STRING database.

First level regulatory network of prdm1a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.1 GO:1900408 negative regulation of cellular response to oxidative stress(GO:1900408) negative regulation of response to oxidative stress(GO:1902883) regulation of oxidative stress-induced cell death(GO:1903201) negative regulation of oxidative stress-induced cell death(GO:1903202)
0.2 0.6 GO:0045649 regulation of macrophage differentiation(GO:0045649)
0.1 3.4 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.1 0.2 GO:0018872 arsonoacetate metabolic process(GO:0018872)
0.1 2.1 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.1 0.2 GO:0035666 response to protozoan(GO:0001562) TRIF-dependent toll-like receptor signaling pathway(GO:0035666) defense response to protozoan(GO:0042832) regulation of isotype switching(GO:0045191) positive regulation of isotype switching(GO:0045830)
0.1 0.3 GO:0019370 leukotriene metabolic process(GO:0006691) leukotriene biosynthetic process(GO:0019370)
0.0 0.3 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.3 GO:0060333 interferon-gamma-mediated signaling pathway(GO:0060333)
0.0 1.1 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.3 GO:0034205 beta-amyloid formation(GO:0034205) amyloid precursor protein catabolic process(GO:0042987)
0.0 0.7 GO:0000731 DNA synthesis involved in DNA repair(GO:0000731)
0.0 0.1 GO:0060155 secretory granule organization(GO:0033363) platelet dense granule organization(GO:0060155)
0.0 0.7 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.2 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.0 0.2 GO:0090259 regulation of retinal ganglion cell axon guidance(GO:0090259)
0.0 0.4 GO:0043248 proteasome assembly(GO:0043248) chaperone-mediated protein complex assembly(GO:0051131)
0.0 0.4 GO:0048922 posterior lateral line neuromast deposition(GO:0048922)
0.0 0.1 GO:2001223 negative regulation of neuron migration(GO:2001223)
0.0 1.9 GO:0071559 transforming growth factor beta receptor signaling pathway(GO:0007179) response to transforming growth factor beta(GO:0071559) cellular response to transforming growth factor beta stimulus(GO:0071560)
0.0 0.2 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.0 0.2 GO:1990845 adaptive thermogenesis(GO:1990845)
0.0 0.1 GO:0002858 response to tumor cell(GO:0002347) natural killer cell cytokine production(GO:0002370) immune response to tumor cell(GO:0002418) natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of natural killer cell cytokine production(GO:0002727) positive regulation of natural killer cell cytokine production(GO:0002729) positive regulation of response to biotic stimulus(GO:0002833) regulation of response to tumor cell(GO:0002834) positive regulation of response to tumor cell(GO:0002836) regulation of immune response to tumor cell(GO:0002837) positive regulation of immune response to tumor cell(GO:0002839) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860) positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
0.0 0.4 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.0 0.3 GO:0045807 positive regulation of endocytosis(GO:0045807)
0.0 0.1 GO:0030859 polarized epithelial cell differentiation(GO:0030859)
0.0 0.3 GO:0046626 regulation of insulin receptor signaling pathway(GO:0046626)
0.0 0.7 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.0 0.2 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.3 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.0 0.7 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 0.9 GO:0010950 positive regulation of endopeptidase activity(GO:0010950) positive regulation of peptidase activity(GO:0010952)
0.0 0.6 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.0 0.9 GO:0021575 hindbrain morphogenesis(GO:0021575)
0.0 0.3 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.1 GO:0051660 establishment of centrosome localization(GO:0051660)
0.0 0.3 GO:0031638 zymogen activation(GO:0031638)
0.0 0.1 GO:1900407 regulation of cellular response to oxidative stress(GO:1900407)
0.0 0.3 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.0 0.3 GO:0001843 neural tube closure(GO:0001843) primary neural tube formation(GO:0014020)
0.0 1.1 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.2 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.5 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 0.2 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.5 GO:0048854 brain morphogenesis(GO:0048854)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0008537 proteasome activator complex(GO:0008537)
0.1 0.7 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.1 3.4 GO:0005839 proteasome core complex(GO:0005839)
0.1 2.1 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.3 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.4 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.2 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.8 GO:0043204 perikaryon(GO:0043204)
0.0 0.1 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.2 GO:0031306 intrinsic component of mitochondrial outer membrane(GO:0031306)
0.0 0.2 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.2 GO:0045095 keratin filament(GO:0045095)
0.0 0.7 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.4 GO:0099569 presynaptic cytoskeleton(GO:0099569)
0.0 1.2 GO:0000786 nucleosome(GO:0000786)
0.0 0.1 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.4 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.2 0.9 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 2.1 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 0.3 GO:0047690 aspartyltransferase activity(GO:0047690)
0.1 0.3 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 0.2 GO:0030791 arsenite methyltransferase activity(GO:0030791) methylarsonite methyltransferase activity(GO:0030792)
0.1 0.2 GO:0036310 annealing helicase activity(GO:0036310)
0.0 0.2 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.0 0.1 GO:0005153 interleukin-8 receptor binding(GO:0005153)
0.0 0.3 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.7 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.3 GO:0000048 peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.0 0.2 GO:0000254 C-4 methylsterol oxidase activity(GO:0000254)
0.0 0.3 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.3 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.5 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.3 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.0 0.1 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.0 0.2 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.1 GO:1903924 estradiol binding(GO:1903924)
0.0 0.1 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 PID ALK2 PATHWAY ALK2 signaling events
0.1 0.7 PID ALK1 PATHWAY ALK1 signaling events
0.1 1.9 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 1.3 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.7 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.5 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.3 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.4 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.3 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.9 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 1.9 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.0 0.1 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS Genes involved in Synthesis of bile acids and bile salts
0.0 1.2 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0 0.3 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.2 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.7 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.2 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.2 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell