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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for prrx1a+prrx1b

Z-value: 1.59

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Transcription factors associated with prrx1a+prrx1b

Gene Symbol Gene ID Gene Info
prrx1a
ENSDARG00000033971 paired related homeobox 1a
prrx1b
ENSDARG00000042027 paired related homeobox 1b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
prrx1adr11_v1_chr2_-_23172708_231727080.864.9e-06Click!
prrx1bdr11_v1_chr20_+_34511678_345116780.561.7e-02Click!

Activity profile of prrx1a+prrx1b motif

Sorted Z-values of prrx1a+prrx1b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr9_-_48397702 5.78 ENSDART00000147169
zgc:172182
zgc:172182
chr9_-_48407408 5.12 ENSDART00000058248
zgc:172182
zgc:172182
chr8_-_21372446 4.91 ENSDART00000061481
ENSDART00000079293
ela2l
elastase 2 like
chr22_-_15562933 4.44 ENSDART00000141528
ankmy1
ankyrin repeat and MYND domain containing 1
chr10_-_17083180 4.21 ENSDART00000170083
fam166b
family with sequence similarity 166, member B
chr20_-_7072487 4.11 ENSDART00000145954
si:ch211-121a2.2
si:ch211-121a2.2
chr22_-_910926 4.01 ENSDART00000180075
FP016205.1

chr9_+_48219111 3.98 ENSDART00000111225
ENSDART00000145972
ccdc173
coiled-coil domain containing 173
chr12_-_990149 3.97 ENSDART00000054367
kdelr2b
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2b
chr21_+_43404945 3.79 ENSDART00000142234
frmd7
FERM domain containing 7
chr18_+_25752592 3.73 ENSDART00000111767
si:ch211-39k3.2
si:ch211-39k3.2
chr7_-_30367650 3.73 ENSDART00000075519
aldh1a2
aldehyde dehydrogenase 1 family, member A2
chr7_+_35075847 3.72 ENSDART00000193469
ENSDART00000037346
ctrb1
chymotrypsinogen B1
chr14_-_49063157 3.69 ENSDART00000021260
sept8b
septin 8b
chr6_+_40354424 3.49 ENSDART00000047416
slc4a8
solute carrier family 4, sodium bicarbonate cotransporter, member 8
chr4_+_9669717 3.42 ENSDART00000004604
si:dkey-153k10.9
si:dkey-153k10.9
chr18_+_5490668 3.40 ENSDART00000167035
mibp2
muscle-specific beta 1 integrin binding protein 2
chr24_-_17067284 3.38 ENSDART00000111237
armc3
armadillo repeat containing 3
chr16_-_45058919 3.26 ENSDART00000177134
gapdhs
glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
chr19_+_43978814 3.24 ENSDART00000102314
nkd3
naked cuticle homolog 3
chr7_-_28148310 3.20 ENSDART00000044208
lmo1
LIM domain only 1
chr21_+_6556635 3.19 ENSDART00000139598
col5a1
procollagen, type V, alpha 1
chr4_-_9909371 3.19 ENSDART00000102656
si:dkey-22l11.6
si:dkey-22l11.6
chr25_-_16146851 3.19 ENSDART00000104043
dkk3b
dickkopf WNT signaling pathway inhibitor 3b
chr5_+_42400777 3.02 ENSDART00000183114
BX548073.8

chr3_+_28953274 2.96 ENSDART00000133528
ENSDART00000103602
lgals2a
lectin, galactoside-binding, soluble, 2a
chr14_-_21123551 2.96 ENSDART00000171679
ENSDART00000165882
si:dkey-74k8.4
si:dkey-74k8.4
chr5_+_42386705 2.95 ENSDART00000143034
pimr58
Pim proto-oncogene, serine/threonine kinase, related 58
chr5_+_42407962 2.95 ENSDART00000188489
BX548073.11

chr25_+_26895394 2.92 ENSDART00000155820
si:dkey-42p14.3
si:dkey-42p14.3
chr4_-_16001118 2.91 ENSDART00000041070
ENSDART00000125389
mest
mesoderm specific transcript
chr21_-_43022048 2.86 ENSDART00000138329
dpysl3
dihydropyrimidinase-like 3
chr5_+_42379517 2.85 ENSDART00000103325
pimr59
Pim proto-oncogene, serine/threonine kinase, related 59
chr17_-_39772999 2.85 ENSDART00000155727
pimr60
Pim proto-oncogene, serine/threonine kinase, related 60
chr5_+_42393896 2.79 ENSDART00000189550
BX548073.13

chr4_+_72723304 2.77 ENSDART00000186791
ENSDART00000158902
ENSDART00000191925
rab3ip
RAB3A interacting protein (rabin3)
chr23_+_39695827 2.76 ENSDART00000113893
ENSDART00000186679
tmco4
transmembrane and coiled-coil domains 4
chr7_+_72003301 2.74 ENSDART00000012918
ENSDART00000182268
ENSDART00000185750
psmd9
proteasome 26S subunit, non-ATPase 9
chr23_+_42810055 2.70 ENSDART00000186647
myl9a
myosin, light chain 9a, regulatory
chr4_-_390431 2.67 ENSDART00000067482
ENSDART00000138500
dynlt1
dynein, light chain, Tctex-type 1
chr7_-_20758825 2.66 ENSDART00000156717
ENSDART00000182629
ENSDART00000179801
chd3
chromodomain helicase DNA binding protein 3
chr1_-_42289704 2.64 ENSDART00000150124
si:ch211-71k14.1
si:ch211-71k14.1
chr16_-_21140097 2.63 ENSDART00000145837
ENSDART00000146500
si:dkey-271j15.3
si:dkey-271j15.3
chr8_-_13046089 2.60 ENSDART00000137784
si:dkey-208b23.5
si:dkey-208b23.5
chr7_+_20344222 2.59 ENSDART00000141186
ENSDART00000139274
ponzr1
plac8 onzin related protein 1
chr7_+_20344032 2.54 ENSDART00000144948
ENSDART00000138786
ponzr1
plac8 onzin related protein 1
chr7_+_26629084 2.54 ENSDART00000101044
ENSDART00000173765
hsbp1a
heat shock factor binding protein 1a
chr8_-_48675775 2.51 ENSDART00000060785
pimr183
Pim proto-oncogene, serine/threonine kinase, related 183
chr6_-_8311044 2.49 ENSDART00000129674
slc44a2
solute carrier family 44 (choline transporter), member 2
chr17_+_31592191 2.49 ENSDART00000153765
si:dkey-13p1.3
si:dkey-13p1.3
chr5_+_40299568 2.49 ENSDART00000142157
arl15a
ADP-ribosylation factor-like 15a
chr12_+_18663154 2.48 ENSDART00000057918
si:ch211-147h1.4
si:ch211-147h1.4
chr15_-_14884332 2.47 ENSDART00000165237
si:ch211-24o8.4
si:ch211-24o8.4
chr15_-_45110011 2.38 ENSDART00000182047
ENSDART00000188662
CABZ01072607.1

chr24_-_38657683 2.35 ENSDART00000154843
si:ch1073-164k15.3
si:ch1073-164k15.3
chr15_-_35246742 2.33 ENSDART00000131479
mff
mitochondrial fission factor
chr12_-_20795867 2.31 ENSDART00000152835
ENSDART00000153424
nme2a
NME/NM23 nucleoside diphosphate kinase 2a
chr10_-_28835771 2.27 ENSDART00000192220
ENSDART00000188436
alcama
activated leukocyte cell adhesion molecule a
chr11_+_12744575 2.21 ENSDART00000131059
ENSDART00000081335
ENSDART00000142481
rbb4l
retinoblastoma binding protein 4, like
chr8_+_21406769 2.21 ENSDART00000135766
si:dkey-163f12.6
si:dkey-163f12.6
chr12_+_3871452 2.21 ENSDART00000066546
nif3l1
NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae)
chr20_-_44496245 2.19 ENSDART00000012229
fkbp1b
FK506 binding protein 1b
chr24_+_35827766 2.17 ENSDART00000144700
si:dkeyp-7a3.1
si:dkeyp-7a3.1
chr1_+_44003654 2.14 ENSDART00000131337
si:dkey-22i16.10
si:dkey-22i16.10
chr7_-_48667056 2.13 ENSDART00000006378
cdkn1ca
cyclin-dependent kinase inhibitor 1Ca
chr6_+_52350443 2.06 ENSDART00000151612
ENSDART00000151349
si:ch211-239j9.1
si:ch211-239j9.1
chr10_-_34107919 2.04 ENSDART00000167428
ENSDART00000145279
pimr144
pimr146
Pim proto-oncogene, serine/threonine kinase, related 144
Pim proto-oncogene, serine/threonine kinase, related 146
chr10_+_6641514 2.02 ENSDART00000150003
si:ch211-57m13.5
si:ch211-57m13.5
chr1_-_56080112 2.00 ENSDART00000075469
ENSDART00000161473
c3a.6
complement component c3a, duplicate 6
chr4_+_2267641 1.98 ENSDART00000165503
si:ch73-89b15.3
si:ch73-89b15.3
chr6_+_6924637 1.98 ENSDART00000065551
ENSDART00000151393
zak
sterile alpha motif and leucine zipper containing kinase AZK
chr18_-_36909773 1.97 ENSDART00000141694
si:ch211-160d20.5
si:ch211-160d20.5
chr3_-_37759147 1.97 ENSDART00000151067
si:dkey-260c8.6
si:dkey-260c8.6
chr4_-_5831522 1.95 ENSDART00000008898
foxm1
forkhead box M1
chr17_-_8268406 1.94 ENSDART00000149873
ENSDART00000064668
ENSDART00000148403
ahi1
Abelson helper integration site 1
chr25_+_34641536 1.92 ENSDART00000167033
CABZ01079011.1

chr2_+_56463167 1.91 ENSDART00000123392
rab11bb
RAB11B, member RAS oncogene family, b
chr20_+_2134816 1.90 ENSDART00000039249
l3mbtl3
l(3)mbt-like 3 (Drosophila)
chr21_-_8420830 1.88 ENSDART00000138040
lhx2a
LIM homeobox 2a
chr21_+_26720803 1.87 ENSDART00000053797
slc3a2b
solute carrier family 3 (amino acid transporter heavy chain), member 2b
chr1_-_46244523 1.80 ENSDART00000143908
si:ch211-138g9.3
si:ch211-138g9.3
chr11_-_45138857 1.78 ENSDART00000166501
cant1b
calcium activated nucleotidase 1b
chr23_-_18913032 1.75 ENSDART00000136678
si:ch211-209j10.6
si:ch211-209j10.6
chr17_-_26926577 1.73 ENSDART00000050202
rcan3
regulator of calcineurin 3
chr21_+_27382893 1.72 ENSDART00000005682
actn3a
actinin alpha 3a
chr23_+_20689255 1.71 ENSDART00000182420
usp21
ubiquitin specific peptidase 21
chr12_+_28856151 1.71 ENSDART00000152969
nfe2l1b
nuclear factor, erythroid 2-like 1b
chr10_-_34089779 1.68 ENSDART00000140070
pimr144
Pim proto-oncogene, serine/threonine kinase, related 144
chr8_-_48675411 1.65 ENSDART00000165081
pimr183
Pim proto-oncogene, serine/threonine kinase, related 183
chr10_-_34772211 1.63 ENSDART00000145450
ENSDART00000134307
dclk1a
doublecortin-like kinase 1a
chr11_-_3860534 1.61 ENSDART00000082425
gata2a
GATA binding protein 2a
chr20_-_52338782 1.61 ENSDART00000109735
ENSDART00000132941
si:ch1073-287p18.1
si:ch1073-287p18.1
chr22_-_32507966 1.57 ENSDART00000104693
pcbp4
poly(rC) binding protein 4
chr12_+_34378733 1.56 ENSDART00000018939
tha1
threonine aldolase 1
chr6_+_9130989 1.56 ENSDART00000162588
rgn
regucalcin
chr20_+_34717403 1.55 ENSDART00000034252
pnocb
prepronociceptin b
chr23_-_16485190 1.55 ENSDART00000155038
si:dkeyp-100a5.4
si:dkeyp-100a5.4
chr24_+_26997798 1.55 ENSDART00000089506
larp4b
La ribonucleoprotein domain family, member 4B
chr1_+_25801648 1.54 ENSDART00000129471
gucy1b1
guanylate cyclase 1 soluble subunit beta 1
chr4_+_78008298 1.53 ENSDART00000174237
cct2
chaperonin containing TCP1, subunit 2 (beta)
chr17_-_19345521 1.52 ENSDART00000082085
gsc
goosecoid
chr25_+_3327071 1.52 ENSDART00000136131
ENSDART00000133243
ldhbb
lactate dehydrogenase Bb
chr9_+_35876927 1.49 ENSDART00000138834
mab21l3
mab-21-like 3
chr3_-_24980067 1.48 ENSDART00000048871
desi1a
desumoylating isopeptidase 1a
chr10_-_26744131 1.48 ENSDART00000020096
ENSDART00000162710
ENSDART00000179853
fgf13b
fibroblast growth factor 13b
chr16_+_31921812 1.48 ENSDART00000176928
ENSDART00000193733
rps9
ribosomal protein S9
chr13_-_9496141 1.47 ENSDART00000131472
pimr152
Pim proto-oncogene, serine/threonine kinase, related 152
chr1_-_49250490 1.47 ENSDART00000150386
si:ch73-6k14.2
si:ch73-6k14.2
chr14_-_46173265 1.46 ENSDART00000164321
zmp:0000000758
zmp:0000000758
chr5_-_72105216 1.44 ENSDART00000044786
thnsl2
threonine synthase-like 2
chr10_-_34243269 1.44 ENSDART00000191406
ENSDART00000131549
pimr167
Pim proto-oncogene, serine/threonine kinase, related 167
chr6_-_3573716 1.43 ENSDART00000026693
dmbx1b
diencephalon/mesencephalon homeobox 1b
chr16_+_23984755 1.43 ENSDART00000145328
apoc2
apolipoprotein C-II
chr10_-_34150577 1.42 ENSDART00000191166
ENSDART00000137763
pimr150
pimr147
Pim proto-oncogene, serine/threonine kinase, related 150
Pim proto-oncogene, serine/threonine kinase, related 147
chr12_+_2428247 1.42 ENSDART00000152529
lrrc18b
leucine rich repeat containing 18b
chr9_-_34300707 1.42 ENSDART00000049805
ildr2
immunoglobulin-like domain containing receptor 2
chr13_-_9546366 1.41 ENSDART00000140408
pimr152
Pim proto-oncogene, serine/threonine kinase, related 152
chr1_-_669717 1.40 ENSDART00000160564
cyyr1
cysteine/tyrosine-rich 1
chr21_-_4468216 1.40 ENSDART00000193272
pimr160
Pim proto-oncogene, serine/threonine kinase, related 160
chr1_-_44899287 1.38 ENSDART00000187522
tcirg1a
T cell immune regulator 1, ATPase H+ transporting V0 subunit a3a
chr10_-_34123733 1.38 ENSDART00000157708
ENSDART00000143954
pimr150
Pim proto-oncogene, serine/threonine kinase, related 150
chr15_-_44512461 1.38 ENSDART00000155456
gria4a
glutamate receptor, ionotropic, AMPA 4a
chr21_-_4327738 1.38 ENSDART00000151457
pimr166
Pim proto-oncogene, serine/threonine kinase, related 166
chr20_-_2134620 1.38 ENSDART00000064375
tmem244
transmembrane protein 244
chr10_-_3332362 1.38 ENSDART00000007577
ENSDART00000055140
tor4aa
torsin family 4, member Aa
chr3_+_33918510 1.37 ENSDART00000055248
alkbh7
alkB homolog 7
chr10_-_34200750 1.36 ENSDART00000137279
pimr148
Pim proto-oncogene, serine/threonine kinase, related 148
chr21_-_4347983 1.36 ENSDART00000151809
pimr164
Pim proto-oncogene, serine/threonine kinase, related 164
chr21_-_4410134 1.36 ENSDART00000151498
pimr162
Pim proto-oncogene, serine/threonine kinase, related 162
chr13_+_9046473 1.36 ENSDART00000136557
pimr152
Pim proto-oncogene, serine/threonine kinase, related 152
chr10_-_34223567 1.35 ENSDART00000184889
pimr145
Pim proto-oncogene, serine/threonine kinase, related 145
chr14_-_46070802 1.34 ENSDART00000038670
elf2a
E74-like factor 2a (ets domain transcription factor)
chr13_+_9091958 1.34 ENSDART00000171741
ENSDART00000147051
pimr155
Pim proto-oncogene, serine/threonine kinase, related 155
chr1_-_45049603 1.34 ENSDART00000023336
rps6
ribosomal protein S6
chr23_+_45282858 1.33 ENSDART00000162353
CABZ01073265.1

chr21_-_4487752 1.32 ENSDART00000168410
pimr161
Pim proto-oncogene, serine/threonine kinase, related 161
chr18_-_15932704 1.32 ENSDART00000127769
plekhg7
pleckstrin homology domain containing, family G (with RhoGef domain) member 7
chr13_+_30903816 1.31 ENSDART00000191727
ercc6
excision repair cross-complementation group 6
chr20_-_46534179 1.31 ENSDART00000060689
eif2b2
eukaryotic translation initiation factor 2B, subunit 2 beta
chr21_-_5393125 1.31 ENSDART00000146061
psmd5
proteasome 26S subunit, non-ATPase 5
chr10_-_34174858 1.30 ENSDART00000131346
pimr145
Pim proto-oncogene, serine/threonine kinase, related 145
chr14_-_24410673 1.30 ENSDART00000125923
cxcl14
chemokine (C-X-C motif) ligand 14
chr21_-_4368035 1.30 ENSDART00000151126
pimr163
Pim proto-oncogene, serine/threonine kinase, related 163
chr4_-_28373909 1.30 ENSDART00000056132
tprkb
Tp53rk binding protein
chr7_+_66822229 1.29 ENSDART00000112109
lyve1a
lymphatic vessel endothelial hyaluronic receptor 1a
chr23_-_12345764 1.29 ENSDART00000133956
phactr3a
phosphatase and actin regulator 3a
chr8_+_1118328 1.28 ENSDART00000081445
ubox5
U-box domain containing 5
chr2_-_30135446 1.27 ENSDART00000141906
trpa1a
transient receptor potential cation channel, subfamily A, member 1a
chr13_+_9112544 1.26 ENSDART00000143138
ENSDART00000131495
pimr153
Pim proto-oncogene, serine/threonine kinase, related 153
chr6_+_43234213 1.26 ENSDART00000112474
arl6ip5a
ADP-ribosylation factor-like 6 interacting protein 5a
chr10_-_17222083 1.25 ENSDART00000134059
depdc5
DEP domain containing 5
chr12_-_32013125 1.24 ENSDART00000153355
grin2cb
glutamate receptor, ionotropic, N-methyl D-aspartate 2Cb
chr24_-_9960290 1.24 ENSDART00000143390
ENSDART00000092975
ENSDART00000184953
vps41
vacuolar protein sorting 41 homolog (S. cerevisiae)
chr10_-_31440500 1.24 ENSDART00000024778
robo3
roundabout, axon guidance receptor, homolog 3 (Drosophila)
chr16_-_31717851 1.24 ENSDART00000169109
rbp5
retinol binding protein 1a, cellular
chr1_+_53954230 1.24 ENSDART00000037729
ENSDART00000159900
ccsapa
centriole, cilia and spindle-associated protein a
chr1_+_12009673 1.23 ENSDART00000080100
slc24a2
solute carrier family 24 (sodium/potassium/calcium exchanger), member 2
chr15_-_21702317 1.23 ENSDART00000155824
IL4I1
si:dkey-40g16.6
chr6_+_49081141 1.21 ENSDART00000131080
ENSDART00000050000
tshba
thyroid stimulating hormone, beta subunit, a
chr1_-_46981134 1.21 ENSDART00000130607
pknox1.2
pbx/knotted 1 homeobox 1.2
chr15_-_17869115 1.21 ENSDART00000112838
atf5b
activating transcription factor 5b
chr20_+_11731039 1.20 ENSDART00000152215
ENSDART00000152585
si:ch211-155o21.3
si:ch211-155o21.3
chr23_-_44226556 1.20 ENSDART00000149115
zgc:158659
zgc:158659
chr9_-_30555725 1.19 ENSDART00000079222
chaf1b
chromatin assembly factor 1, subunit B
chr6_+_40661703 1.19 ENSDART00000142492
eno1b
enolase 1b, (alpha)
chr13_+_9162465 1.18 ENSDART00000102108
pimr152
Pim proto-oncogene, serine/threonine kinase, related 152
chr21_-_4428354 1.17 ENSDART00000151174
CT027677.2

chr19_+_9174166 1.17 ENSDART00000104637
ENSDART00000150968
si:ch211-81a5.8
si:ch211-81a5.8
chr10_+_29698467 1.17 ENSDART00000163402
dlg2
discs, large homolog 2 (Drosophila)
chr25_+_31267268 1.16 ENSDART00000181239
tnni2a.3
troponin I type 2a (skeletal, fast), tandem duplicate 3
chr22_-_38274188 1.16 ENSDART00000139420
ENSDART00000015117
elavl2
ELAV like neuron-specific RNA binding protein 2
chr3_+_12440099 1.14 ENSDART00000158060
vasnb
vasorin b
chr19_-_7495006 1.14 ENSDART00000148836
rfx5
regulatory factor X, 5
chr4_+_74141400 1.14 ENSDART00000166994
trim24
tripartite motif containing 24
chr15_+_42285643 1.13 ENSDART00000152731
scaf4b
SR-related CTD-associated factor 4b
chr5_+_25074648 1.12 ENSDART00000188951
mrpl41
mitochondrial ribosomal protein L41
chr23_+_26733232 1.12 ENSDART00000035080
zgc:158263
zgc:158263
chr20_-_30920356 1.11 ENSDART00000022951
kif25
kinesin family member 25
chr14_+_48964628 1.11 ENSDART00000105427
mif
macrophage migration inhibitory factor
chr13_+_9184801 1.10 ENSDART00000133916
ENSDART00000144483
pimr156
Pim proto-oncogene, serine/threonine kinase, related 156
chr17_+_30545895 1.10 ENSDART00000076739
nhsl1a
NHS-like 1a
chr5_+_41322783 1.09 ENSDART00000097546
arid3c
AT rich interactive domain 3C (BRIGHT-like)
chr22_+_14051894 1.08 ENSDART00000142548
aox6
aldehyde oxidase 6
chr18_-_21271373 1.08 ENSDART00000060001
pnp6
purine nucleoside phosphorylase 6
chr20_+_24448007 1.08 ENSDART00000139866
si:dkey-273g18.1
si:dkey-273g18.1
chr25_+_18964782 1.07 ENSDART00000017299
tdg.1
thymine DNA glycosylase, tandem duplicate 1
chr16_-_41944765 1.07 ENSDART00000142648
gramd1a
GRAM domain containing 1A
chr13_-_36535128 1.06 ENSDART00000043312
srsf5a
serine/arginine-rich splicing factor 5a
chr14_+_8475007 1.06 ENSDART00000148210
dnajc4
DnaJ (Hsp40) homolog, subfamily C, member 4
chr1_-_43727418 1.05 ENSDART00000133715
ENSDART00000074597
ENSDART00000132542
ENSDART00000181792
bdh2
SLC9B2
3-hydroxybutyrate dehydrogenase, type 2
si:dkey-162b23.4
chr5_-_11943750 1.05 ENSDART00000074979
rnft2
ring finger protein, transmembrane 2
chr10_-_34741738 1.05 ENSDART00000163072
dclk1a
doublecortin-like kinase 1a
chr6_+_41191482 1.05 ENSDART00000000877
opn1mw3
opsin 1 (cone pigments), medium-wave-sensitive, 3
chr20_+_46371458 1.05 ENSDART00000152912
adgrg11
adhesion G protein-coupled receptor G11
chr25_+_22730490 1.04 ENSDART00000149455
abcc8
ATP-binding cassette, sub-family C (CFTR/MRP), member 8
chr23_+_25893020 1.04 ENSDART00000144769
pkig
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
chr2_+_16781015 1.03 ENSDART00000155147
ENSDART00000003845
tfa
transferrin-a
chr14_-_1355544 1.02 ENSDART00000060417
cetn4
centrin 4
chr7_+_20030888 1.02 ENSDART00000192808
slc16a13
solute carrier family 16, member 13 (monocarboxylic acid transporter 13)
chr1_-_9195629 1.02 ENSDART00000143587
ENSDART00000192174
ern2
endoplasmic reticulum to nucleus signaling 2

Network of associatons between targets according to the STRING database.

First level regulatory network of prrx1a+prrx1b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.7 GO:0061113 pancreas morphogenesis(GO:0061113)
0.9 2.6 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.6 2.5 GO:0015871 choline transport(GO:0015871)
0.6 4.0 GO:0006621 protein retention in ER lumen(GO:0006621)
0.5 1.6 GO:1902893 pri-miRNA transcription from RNA polymerase II promoter(GO:0061614) regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902893) positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895)
0.5 1.6 GO:0042364 L-ascorbic acid metabolic process(GO:0019852) water-soluble vitamin biosynthetic process(GO:0042364)
0.5 5.1 GO:0072088 renal tubule morphogenesis(GO:0061333) nephron tubule morphogenesis(GO:0072078) nephron epithelium morphogenesis(GO:0072088)
0.4 1.8 GO:0046166 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.4 1.2 GO:0060292 long term synaptic depression(GO:0060292)
0.4 1.5 GO:0099548 trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by nitric oxide(GO:0099548)
0.4 1.5 GO:0050955 thermoception(GO:0050955) detection of temperature stimulus involved in thermoception(GO:0050960) detection of temperature stimulus involved in sensory perception(GO:0050961)
0.4 1.5 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.3 1.6 GO:0033119 negative regulation of RNA splicing(GO:0033119) negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.3 1.3 GO:0098908 regulation of neuronal action potential(GO:0098908)
0.3 2.1 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.3 0.3 GO:0021559 trigeminal nerve development(GO:0021559) glossopharyngeal nerve development(GO:0021563)
0.3 1.7 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.3 4.1 GO:0043248 proteasome assembly(GO:0043248)
0.3 1.6 GO:0006545 glycine biosynthetic process(GO:0006545)
0.3 1.3 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.3 4.4 GO:0051764 actin crosslink formation(GO:0051764)
0.2 2.5 GO:0034605 cellular response to heat(GO:0034605)
0.2 0.9 GO:0003322 pancreatic A cell development(GO:0003322)
0.2 0.6 GO:0009912 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.2 1.0 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.2 0.6 GO:0034375 high-density lipoprotein particle remodeling(GO:0034375)
0.2 1.9 GO:0044458 motile cilium assembly(GO:0044458)
0.2 0.8 GO:0015868 intracellular nucleoside transport(GO:0015859) purine nucleoside transmembrane transport(GO:0015860) purine nucleotide transport(GO:0015865) ATP transport(GO:0015867) purine ribonucleotide transport(GO:0015868) adenine nucleotide transport(GO:0051503) mitochondrial ATP transmembrane transport(GO:1990544)
0.2 0.6 GO:0097264 self proteolysis(GO:0097264)
0.2 2.6 GO:0090303 positive regulation of wound healing(GO:0090303)
0.2 1.2 GO:1901673 regulation of mitotic spindle assembly(GO:1901673)
0.2 1.1 GO:0019184 nonribosomal peptide biosynthetic process(GO:0019184)
0.2 0.9 GO:0034695 response to prostaglandin E(GO:0034695) cellular response to prostaglandin E stimulus(GO:0071380)
0.2 1.0 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.2 1.0 GO:0021846 cell proliferation in forebrain(GO:0021846)
0.2 0.5 GO:0007414 axonal defasciculation(GO:0007414)
0.2 2.0 GO:0071156 regulation of cell cycle arrest(GO:0071156)
0.2 1.0 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.2 1.4 GO:0046459 short-chain fatty acid metabolic process(GO:0046459)
0.2 0.6 GO:0015919 peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.2 1.2 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.2 3.5 GO:0015701 bicarbonate transport(GO:0015701)
0.1 1.2 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.1 2.3 GO:0046051 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.1 2.5 GO:0060079 excitatory postsynaptic potential(GO:0060079)
0.1 0.5 GO:0051012 microtubule sliding(GO:0051012)
0.1 0.8 GO:0021767 mammillary body development(GO:0021767) social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.1 0.5 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.1 0.9 GO:0036268 swimming(GO:0036268)
0.1 0.5 GO:0015677 copper ion import(GO:0015677)
0.1 0.9 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.1 0.8 GO:0031507 heterochromatin assembly(GO:0031507)
0.1 0.6 GO:0003261 cardiac muscle progenitor cell migration to the midline involved in heart field formation(GO:0003261)
0.1 3.4 GO:0070831 basement membrane assembly(GO:0070831)
0.1 2.9 GO:0010883 regulation of lipid storage(GO:0010883)
0.1 0.5 GO:2001046 positive regulation of integrin-mediated signaling pathway(GO:2001046)
0.1 43.4 GO:0046777 protein autophosphorylation(GO:0046777)
0.1 0.8 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.1 0.8 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1 0.8 GO:0060221 retinal rod cell differentiation(GO:0060221)
0.1 1.5 GO:0010717 regulation of epithelial to mesenchymal transition(GO:0010717)
0.1 0.7 GO:0021877 forebrain neuron fate commitment(GO:0021877)
0.1 0.9 GO:0042554 superoxide anion generation(GO:0042554)
0.1 1.8 GO:0061074 regulation of neural retina development(GO:0061074)
0.1 0.3 GO:0046333 octopamine biosynthetic process(GO:0006589) dopamine catabolic process(GO:0042420) norepinephrine biosynthetic process(GO:0042421) octopamine metabolic process(GO:0046333)
0.1 1.3 GO:0006285 base-excision repair, AP site formation(GO:0006285)
0.1 0.8 GO:2001271 negative regulation of execution phase of apoptosis(GO:1900118) regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1 0.7 GO:0042362 fat-soluble vitamin biosynthetic process(GO:0042362)
0.1 1.5 GO:0051452 vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452)
0.1 2.0 GO:0042953 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.1 1.5 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 1.4 GO:0097300 necrotic cell death(GO:0070265) programmed necrotic cell death(GO:0097300)
0.1 1.2 GO:0071679 commissural neuron axon guidance(GO:0071679)
0.1 0.1 GO:0048331 axial mesoderm structural organization(GO:0048331) mesoderm structural organization(GO:0048338)
0.1 0.2 GO:0060898 eye field cell fate commitment involved in camera-type eye formation(GO:0060898)
0.1 0.8 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.1 0.9 GO:0001765 membrane raft assembly(GO:0001765) plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) caveola assembly(GO:0070836)
0.1 3.2 GO:0030199 collagen fibril organization(GO:0030199)
0.1 1.8 GO:0021551 central nervous system morphogenesis(GO:0021551)
0.1 1.0 GO:0019731 antibacterial humoral response(GO:0019731)
0.1 1.0 GO:0071357 response to type I interferon(GO:0034340) type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.1 0.6 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.1 0.7 GO:0046959 learning(GO:0007612) nonassociative learning(GO:0046958) habituation(GO:0046959)
0.1 0.9 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.1 0.6 GO:0044550 melanin biosynthetic process(GO:0042438) secondary metabolite biosynthetic process(GO:0044550)
0.1 0.7 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.1 7.5 GO:0070121 Kupffer's vesicle development(GO:0070121)
0.1 4.1 GO:0006096 glycolytic process(GO:0006096)
0.1 0.9 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 1.0 GO:0036158 outer dynein arm assembly(GO:0036158)
0.1 2.2 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 0.5 GO:0043201 response to leucine(GO:0043201) cellular response to leucine(GO:0071233) regulation of response to reactive oxygen species(GO:1901031) cellular response to leucine starvation(GO:1990253)
0.1 0.5 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.7 GO:0043046 DNA methylation involved in gamete generation(GO:0043046)
0.1 1.2 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.1 0.7 GO:0050909 sensory perception of taste(GO:0050909)
0.1 0.6 GO:1904071 presynaptic active zone assembly(GO:1904071)
0.1 0.3 GO:0006086 acetyl-CoA biosynthetic process from pyruvate(GO:0006086)
0.1 0.9 GO:0042407 cristae formation(GO:0042407)
0.1 0.2 GO:0032776 DNA methylation on cytosine(GO:0032776)
0.1 2.3 GO:0060536 cartilage morphogenesis(GO:0060536)
0.1 1.2 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.4 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.5 GO:0048790 maintenance of presynaptic active zone structure(GO:0048790) maintenance of synapse structure(GO:0099558) presynaptic active zone organization(GO:1990709)
0.0 0.4 GO:0048208 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.0 0.6 GO:0019747 regulation of isoprenoid metabolic process(GO:0019747) regulation of vitamin metabolic process(GO:0030656) regulation of retinoic acid biosynthetic process(GO:1900052)
0.0 1.0 GO:0010824 regulation of centrosome duplication(GO:0010824)
0.0 0.3 GO:0061298 retina vasculature development in camera-type eye(GO:0061298)
0.0 0.3 GO:0099525 synaptic vesicle docking(GO:0016081) presynaptic dense core granule exocytosis(GO:0099525)
0.0 0.1 GO:0046635 positive regulation of alpha-beta T cell activation(GO:0046635)
0.0 0.3 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.0 1.3 GO:0060117 auditory receptor cell development(GO:0060117)
0.0 0.6 GO:0001964 startle response(GO:0001964)
0.0 0.7 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.5 GO:0046887 positive regulation of hormone secretion(GO:0046887)
0.0 0.1 GO:0050957 equilibrioception(GO:0050957)
0.0 0.6 GO:0007257 activation of JUN kinase activity(GO:0007257) positive regulation of JUN kinase activity(GO:0043507)
0.0 0.6 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 2.8 GO:0061640 cytoskeleton-dependent cytokinesis(GO:0061640)
0.0 1.5 GO:0071696 ectodermal placode development(GO:0071696)
0.0 0.4 GO:0060416 growth hormone receptor signaling pathway(GO:0060396) response to growth hormone(GO:0060416) cellular response to growth hormone stimulus(GO:0071378)
0.0 0.5 GO:0060030 dorsal convergence(GO:0060030)
0.0 0.4 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.1 GO:0071632 optomotor response(GO:0071632)
0.0 0.1 GO:0001774 microglial cell activation(GO:0001774)
0.0 0.3 GO:0030216 keratinocyte differentiation(GO:0030216)
0.0 2.1 GO:0006956 complement activation(GO:0006956)
0.0 0.7 GO:0060037 pharyngeal system development(GO:0060037)
0.0 0.7 GO:1903845 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.0 0.2 GO:0000423 macromitophagy(GO:0000423)
0.0 1.2 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 0.2 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.0 1.0 GO:0036269 swimming behavior(GO:0036269)
0.0 0.9 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 0.1 GO:0014856 skeletal muscle cell proliferation(GO:0014856) regulation of skeletal muscle cell proliferation(GO:0014857)
0.0 1.2 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.0 0.9 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.9 GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation(GO:0050731)
0.0 0.9 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.0 0.2 GO:0015813 acidic amino acid transport(GO:0015800) aspartate transport(GO:0015810) L-glutamate transport(GO:0015813) malate-aspartate shuttle(GO:0043490)
0.0 0.4 GO:1902017 regulation of cilium assembly(GO:1902017)
0.0 0.2 GO:0060122 inner ear receptor stereocilium organization(GO:0060122)
0.0 1.2 GO:0034599 cellular response to oxidative stress(GO:0034599)
0.0 0.3 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.0 1.1 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.7 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 0.3 GO:0036065 fucosylation(GO:0036065)
0.0 1.0 GO:0007602 phototransduction(GO:0007602)
0.0 1.5 GO:0007492 endoderm development(GO:0007492)
0.0 1.1 GO:0001946 lymphangiogenesis(GO:0001946)
0.0 0.7 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.2 GO:0007398 ectoderm development(GO:0007398)
0.0 0.4 GO:0010962 regulation of glycogen biosynthetic process(GO:0005979) regulation of glucan biosynthetic process(GO:0010962)
0.0 0.2 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560) protein to membrane docking(GO:0022615)
0.0 0.8 GO:0000077 DNA damage checkpoint(GO:0000077)
0.0 1.1 GO:0060215 primitive hemopoiesis(GO:0060215)
0.0 2.2 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)
0.0 0.1 GO:0007634 optokinetic behavior(GO:0007634)
0.0 0.1 GO:0036368 cone photoresponse recovery(GO:0036368)
0.0 0.8 GO:0090090 negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.0 1.7 GO:0019932 second-messenger-mediated signaling(GO:0019932)
0.0 1.2 GO:0009755 hormone-mediated signaling pathway(GO:0009755)
0.0 0.4 GO:0010669 epithelial structure maintenance(GO:0010669)
0.0 1.3 GO:0060326 cell chemotaxis(GO:0060326)
0.0 0.3 GO:0030641 regulation of cellular pH(GO:0030641)
0.0 0.3 GO:0050708 regulation of protein secretion(GO:0050708)
0.0 0.5 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 1.2 GO:0010506 regulation of autophagy(GO:0010506)
0.0 1.1 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.3 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 1.5 GO:0070646 protein modification by small protein removal(GO:0070646)
0.0 0.2 GO:0071594 T cell differentiation in thymus(GO:0033077) thymocyte aggregation(GO:0071594)
0.0 1.4 GO:0007266 Rho protein signal transduction(GO:0007266)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.2 GO:0005588 collagen type V trimer(GO:0005588)
0.7 2.8 GO:0070319 Golgi to plasma membrane transport vesicle(GO:0070319)
0.3 1.0 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.3 1.2 GO:0033186 CAF-1 complex(GO:0033186)
0.3 0.8 GO:0031417 NatC complex(GO:0031417)
0.2 4.0 GO:0005801 cis-Golgi network(GO:0005801)
0.2 0.7 GO:0033391 chromatoid body(GO:0033391)
0.2 1.3 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.2 1.3 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.2 1.3 GO:1990130 Iml1 complex(GO:1990130)
0.2 1.2 GO:0030897 HOPS complex(GO:0030897)
0.2 1.6 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.2 1.5 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.1 1.2 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 0.6 GO:0060171 stereocilium membrane(GO:0060171)
0.1 1.5 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.1 0.5 GO:0008247 1-alkyl-2-acetylglycerophosphocholine esterase complex(GO:0008247)
0.1 1.7 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 1.2 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.1 1.5 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 1.7 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 0.9 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 3.6 GO:0044447 axoneme part(GO:0044447)
0.1 1.0 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.1 0.4 GO:0070195 growth hormone receptor complex(GO:0070195)
0.1 4.8 GO:0030426 growth cone(GO:0030426)
0.1 3.0 GO:0043679 axon terminus(GO:0043679)
0.1 0.6 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.1 0.9 GO:0061617 MICOS complex(GO:0061617)
0.1 0.3 GO:0035301 Hedgehog signaling complex(GO:0035301)
0.1 2.8 GO:0032156 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.1 0.6 GO:0098982 GABA-ergic synapse(GO:0098982)
0.1 0.6 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 1.2 GO:0031594 neuromuscular junction(GO:0031594)
0.1 0.5 GO:0061700 GATOR2 complex(GO:0061700)
0.1 0.3 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.1 0.3 GO:0033181 plasma membrane proton-transporting V-type ATPase complex(GO:0033181)
0.0 0.3 GO:0030891 VCB complex(GO:0030891)
0.0 2.1 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.4 GO:0045171 intercellular bridge(GO:0045171)
0.0 2.2 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 1.8 GO:0005861 troponin complex(GO:0005861)
0.0 0.5 GO:0014704 intercalated disc(GO:0014704)
0.0 0.6 GO:0031209 SCAR complex(GO:0031209)
0.0 3.4 GO:0055037 recycling endosome(GO:0055037)
0.0 2.1 GO:0098878 ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.0 0.8 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 1.1 GO:0035869 ciliary transition zone(GO:0035869)
0.0 1.5 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 1.3 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.5 GO:0048788 cytoskeleton of presynaptic active zone(GO:0048788) presynaptic active zone cytoplasmic component(GO:0098831) presynaptic cytoskeleton(GO:0099569)
0.0 0.1 GO:0042709 succinate-CoA ligase complex(GO:0042709)
0.0 0.4 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.3 GO:0005869 dynactin complex(GO:0005869)
0.0 0.5 GO:0005844 polysome(GO:0005844)
0.0 0.4 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.5 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 1.7 GO:0005604 basement membrane(GO:0005604)
0.0 0.4 GO:0046930 pore complex(GO:0046930)
0.0 0.3 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.3 GO:0031430 M band(GO:0031430)
0.0 0.5 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 1.2 GO:0005814 centriole(GO:0005814)
0.0 0.3 GO:0045180 basal cortex(GO:0045180)
0.0 0.1 GO:0031931 TORC1 complex(GO:0031931)
0.0 1.7 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 0.3 GO:0000780 condensed nuclear chromosome kinetochore(GO:0000778) condensed nuclear chromosome, centromeric region(GO:0000780)
0.0 1.1 GO:0030018 Z disc(GO:0030018)
0.0 0.1 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.0 GO:0005854 nascent polypeptide-associated complex(GO:0005854)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 4.0 GO:0046923 ER retention sequence binding(GO:0046923)
0.8 3.3 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.6 3.2 GO:0039706 co-receptor binding(GO:0039706)
0.6 2.5 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.5 3.4 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262)
0.4 1.8 GO:0004807 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
0.4 1.1 GO:0001729 ceramide kinase activity(GO:0001729)
0.4 1.1 GO:0016623 aldehyde oxidase activity(GO:0004031) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.3 2.0 GO:0004104 cholinesterase activity(GO:0004104)
0.3 1.4 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.3 1.7 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.3 1.9 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.3 3.7 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.3 2.1 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.3 1.5 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.2 3.5 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.2 2.9 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.2 2.2 GO:0016936 galactoside binding(GO:0016936)
0.2 1.5 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.2 1.0 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.2 0.8 GO:0005471 ATP:ADP antiporter activity(GO:0005471)
0.2 1.1 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.2 1.1 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.2 0.7 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.2 0.9 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.2 1.0 GO:0030291 protein serine/threonine kinase inhibitor activity(GO:0030291)
0.2 0.6 GO:0048407 platelet-derived growth factor-activated receptor activity(GO:0005017) platelet-derived growth factor binding(GO:0048407)
0.1 1.2 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 1.3 GO:0008263 mismatch base pair DNA N-glycosylase activity(GO:0000700) pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263)
0.1 2.1 GO:0051117 ATPase binding(GO:0051117)
0.1 0.5 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.1 1.2 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.1 0.5 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.1 0.7 GO:0043531 ADP binding(GO:0043531)
0.1 1.1 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.1 1.6 GO:0031628 opioid receptor binding(GO:0031628)
0.1 0.6 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.1 0.8 GO:0042834 peptidoglycan binding(GO:0042834)
0.1 0.3 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
0.1 0.8 GO:0030160 GKAP/Homer scaffold activity(GO:0030160) ionotropic glutamate receptor binding(GO:0035255)
0.1 1.2 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.1 1.9 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.1 0.9 GO:0052659 inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.1 0.4 GO:0072570 ADP-D-ribose binding(GO:0072570) mono-ADP-D-ribose binding(GO:0072571)
0.1 1.0 GO:0016918 retinal binding(GO:0016918)
0.1 0.6 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 1.4 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.1 0.4 GO:0004903 growth hormone receptor activity(GO:0004903)
0.1 1.0 GO:0004046 aminoacylase activity(GO:0004046)
0.1 0.5 GO:0031705 bombesin receptor binding(GO:0031705)
0.1 0.3 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.1 0.9 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.1 1.5 GO:0004383 guanylate cyclase activity(GO:0004383)
0.1 1.7 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.1 0.4 GO:0015288 porin activity(GO:0015288)
0.1 2.3 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.1 1.0 GO:0045503 dynein light chain binding(GO:0045503)
0.1 0.6 GO:0004096 catalase activity(GO:0004096)
0.1 0.3 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.1 0.6 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.1 0.4 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 0.5 GO:0070728 leucine binding(GO:0070728)
0.1 1.1 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.1 1.4 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1 1.4 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.1 0.9 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.1 1.7 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.1 0.2 GO:0102344 3-hydroxyacyl-CoA dehydratase activity(GO:0018812) 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.0 0.7 GO:0070403 NAD+ binding(GO:0070403)
0.0 1.6 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 3.7 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 2.2 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.2 GO:0019778 Atg12 activating enzyme activity(GO:0019778) Atg8 activating enzyme activity(GO:0019779)
0.0 0.5 GO:0070840 dynein complex binding(GO:0070840)
0.0 1.1 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0 4.2 GO:0008201 heparin binding(GO:0008201)
0.0 0.5 GO:0005158 insulin receptor binding(GO:0005158)
0.0 38.2 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.0 1.2 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 1.2 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.1 GO:0015105 arsenite transmembrane transporter activity(GO:0015105)
0.0 0.6 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.1 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0 0.1 GO:1990174 phosphodiesterase decapping endonuclease activity(GO:1990174)
0.0 0.2 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750) lipoprotein particle receptor binding(GO:0070325)
0.0 0.6 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.7 GO:0017046 peptide hormone binding(GO:0017046)
0.0 0.4 GO:0010851 cyclase regulator activity(GO:0010851)
0.0 1.1 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.6 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.3 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 0.1 GO:0004776 succinate-CoA ligase activity(GO:0004774) succinate-CoA ligase (ADP-forming) activity(GO:0004775) succinate-CoA ligase (GDP-forming) activity(GO:0004776)
0.0 0.4 GO:2001069 glycogen binding(GO:2001069)
0.0 2.3 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.6 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.0 1.5 GO:0019905 syntaxin binding(GO:0019905)
0.0 1.0 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.7 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 0.9 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 1.3 GO:0008009 chemokine activity(GO:0008009)
0.0 4.4 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 1.8 GO:0003678 DNA helicase activity(GO:0003678)
0.0 4.6 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.2 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 0.2 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.2 GO:0005221 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.1 GO:0015172 L-glutamate transmembrane transporter activity(GO:0005313) acidic amino acid transmembrane transporter activity(GO:0015172)
0.0 1.9 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.1 GO:0033781 cholesterol 24-hydroxylase activity(GO:0033781)
0.0 0.4 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 1.8 GO:0101005 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.1 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 1.7 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.8 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 2.0 GO:0004866 endopeptidase inhibitor activity(GO:0004866)
0.0 0.3 GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.0 0.4 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.6 GO:0008094 DNA-dependent ATPase activity(GO:0008094)
0.0 0.9 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 1.7 GO:0060090 binding, bridging(GO:0060090)
0.0 1.5 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.3 GO:0005112 Notch binding(GO:0005112)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.0 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 1.9 PID CONE PATHWAY Visual signal transduction: Cones
0.1 3.7 NABA COLLAGENS Genes encoding collagen proteins
0.1 0.7 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1 0.9 PID RAC1 PATHWAY RAC1 signaling pathway
0.1 1.0 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 0.7 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 3.4 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 1.1 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.6 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 1.3 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 1.8 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.2 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.0 0.5 PID RAS PATHWAY Regulation of Ras family activation
0.0 1.0 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.0 1.7 PID CMYB PATHWAY C-MYB transcription factor network
0.0 1.1 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 1.0 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.2 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.5 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.3 PID ARF 3PATHWAY Arf1 pathway
0.0 0.4 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.4 PID ATR PATHWAY ATR signaling pathway
0.0 0.3 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.1 PID CXCR3 PATHWAY CXCR3-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.7 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.3 2.9 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.2 3.0 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.2 1.7 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.2 2.5 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.1 1.5 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.1 0.9 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1 0.5 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 1.0 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.1 3.3 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 3.5 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.1 0.7 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.1 1.5 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.1 1.0 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 1.8 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.1 4.8 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 0.5 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.1 1.1 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 0.9 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 1.1 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 2.2 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 1.0 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.5 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.0 0.3 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.9 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.4 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.3 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.2 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.6 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.8 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.0 1.0 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.5 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.4 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.1 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.1 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.1 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.7 REACTOME TRANSPORT OF GLUCOSE AND OTHER SUGARS BILE SALTS AND ORGANIC ACIDS METAL IONS AND AMINE COMPOUNDS Genes involved in Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
0.0 1.3 REACTOME TRANSLATION Genes involved in Translation
0.0 0.3 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins