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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for rarga

Z-value: 0.71

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Transcription factors associated with rarga

Gene Symbol Gene ID Gene Info
rarga
ENSDARG00000034117 retinoic acid receptor gamma a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
rargadr11_v1_chr23_+_35847538_35847538-0.815.3e-05Click!

Activity profile of rarga motif

Sorted Z-values of rarga motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_39786222 2.53 ENSDART00000154515
pimr62
Pim proto-oncogene, serine/threonine kinase, related 62
chr16_+_25126935 2.12 ENSDART00000058945
zgc:92590
zgc:92590
chr9_-_48397702 2.06 ENSDART00000147169
zgc:172182
zgc:172182
chr5_+_42467867 1.98 ENSDART00000172028
pimr58
Pim proto-oncogene, serine/threonine kinase, related 58
chr21_+_30355767 1.82 ENSDART00000189948
CR749164.1

chr7_+_20344222 1.61 ENSDART00000141186
ENSDART00000139274
ponzr1
plac8 onzin related protein 1
chr25_+_3326885 1.37 ENSDART00000104866
ldhbb
lactate dehydrogenase Bb
chr15_-_20933574 1.32 ENSDART00000152648
ENSDART00000152448
ENSDART00000152244
usp2a
ubiquitin specific peptidase 2a
chr7_-_58729894 1.24 ENSDART00000149347
chchd7
coiled-coil-helix-coiled-coil-helix domain containing 7
chr7_+_20344032 1.23 ENSDART00000144948
ENSDART00000138786
ponzr1
plac8 onzin related protein 1
chr6_+_52235441 1.22 ENSDART00000056319
cox6c
cytochrome c oxidase subunit VIc
chr11_-_24681292 1.19 ENSDART00000089601
olfml3b
olfactomedin-like 3b
chr7_+_20344486 1.18 ENSDART00000134004
ENSDART00000139685
ponzr1
plac8 onzin related protein 1
chr19_+_40856534 1.17 ENSDART00000051950
gngt1
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr12_-_30583668 1.16 ENSDART00000153406
casp7
caspase 7, apoptosis-related cysteine peptidase
chr4_-_13567387 1.15 ENSDART00000132971
ENSDART00000102010
mdm1
Mdm1 nuclear protein homolog (mouse)
chr22_+_28969071 1.15 ENSDART00000163427
pimr95
Pim proto-oncogene, serine/threonine kinase, related 95
chr13_-_12660318 1.12 ENSDART00000008498
adh8a
alcohol dehydrogenase 8a
chr17_-_26610814 1.10 ENSDART00000133402
ENSDART00000016608
mrpl57
mitochondrial ribosomal protein L57
chr21_-_43117327 1.10 ENSDART00000122352
p4ha2
procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide 2
chr15_+_46386261 1.09 ENSDART00000191793
igsf11
immunoglobulin superfamily member 11
chr19_-_42424599 1.07 ENSDART00000077042
zgc:153441
zgc:153441
chr5_+_20693724 1.06 ENSDART00000141368
si:ch211-240b21.2
si:ch211-240b21.2
chr1_+_54626491 1.05 ENSDART00000136063
si:ch211-202h22.9
si:ch211-202h22.9
chr1_-_9109699 0.97 ENSDART00000147833
vap
vascular associated protein
chr8_-_13471916 0.95 ENSDART00000146558
pimr105
Pim proto-oncogene, serine/threonine kinase, related 105
chr25_+_3327071 0.94 ENSDART00000136131
ENSDART00000133243
ldhbb
lactate dehydrogenase Bb
chr7_-_29271738 0.92 ENSDART00000109030
herc1
HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
chr10_+_2981090 0.89 ENSDART00000111830
zfyve16
zinc finger, FYVE domain containing 16
chr21_-_308852 0.87 ENSDART00000151613
lhfpl2a
LHFPL tetraspan subfamily member 2a
chr8_-_13428740 0.87 ENSDART00000131826
CR354547.3

chr15_+_17321218 0.86 ENSDART00000143796
cltcb
clathrin, heavy chain b (Hc)
chr11_-_42315748 0.86 ENSDART00000169853
slmapa
sarcolemma associated protein a
chr1_+_54043563 0.84 ENSDART00000149760
triobpa
TRIO and F-actin binding protein a
chr7_-_27033080 0.84 ENSDART00000173516
nucb2a
nucleobindin 2a
chr22_+_29067388 0.80 ENSDART00000133673
pimr100
Pim proto-oncogene, serine/threonine kinase, related 100
chr16_-_23471387 0.78 ENSDART00000180899
CR533578.1

chr15_+_3284416 0.77 ENSDART00000187665
ENSDART00000171723
foxo1a
forkhead box O1 a
chr12_-_24928497 0.76 ENSDART00000002465
msh2
mutS homolog 2 (E. coli)
chr6_-_20952187 0.76 ENSDART00000074327
igfbp2a
insulin-like growth factor binding protein 2a
chr6_+_11990733 0.74 ENSDART00000151075
baz2ba
bromodomain adjacent to zinc finger domain, 2Ba
chr21_-_2299002 0.73 ENSDART00000168712
si:ch73-299h12.6
si:ch73-299h12.6
chr16_-_17258111 0.72 ENSDART00000079497
emg1
EMG1 N1-specific pseudouridine methyltransferase
chr14_-_33454595 0.70 ENSDART00000109615
ENSDART00000173267
ENSDART00000185737
ENSDART00000190989
tmem255a
transmembrane protein 255A
chr21_-_5879897 0.70 ENSDART00000184034
rpl35
ribosomal protein L35
chr20_-_14665002 0.70 ENSDART00000152816
scrn2
secernin 2
chr1_+_44767657 0.70 ENSDART00000073717
si:dkey-9i23.4
si:dkey-9i23.4
chr3_-_15139293 0.70 ENSDART00000161213
ENSDART00000146053
fam173a
family with sequence similarity 173, member A
chr8_-_13419049 0.69 ENSDART00000133656
pimr101
Pim proto-oncogene, serine/threonine kinase, related 101
chr6_-_10835849 0.68 ENSDART00000005903
ENSDART00000135065
atp5mc3b
ATP synthase membrane subunit c locus 3b
chr11_+_43363075 0.67 ENSDART00000179934
CU929458.1

chr2_+_24536762 0.66 ENSDART00000144149
angptl4
angiopoietin-like 4
chr12_+_38695808 0.66 ENSDART00000188726
ENSDART00000003339
dnai2b
dynein, axonemal, intermediate chain 2b
chr1_-_46632948 0.65 ENSDART00000148893
ENSDART00000053232
cdadc1
cytidine and dCMP deaminase domain containing 1
chr5_+_19343880 0.65 ENSDART00000148130
acacb
acetyl-CoA carboxylase beta
chr12_+_27096835 0.65 ENSDART00000149475
ttll6
tubulin tyrosine ligase-like family, member 6
chr8_-_25329967 0.65 ENSDART00000139682
eps8l3b
EPS8-like 3b
chr8_-_13442871 0.64 ENSDART00000144887
pimr106
Pim proto-oncogene, serine/threonine kinase, related 106
chr9_-_303658 0.64 ENSDART00000160338
si:ch211-166e11.5
si:ch211-166e11.5
chr7_+_15266093 0.62 ENSDART00000124676
sv2ba
synaptic vesicle glycoprotein 2Ba
chr3_+_62356578 0.61 ENSDART00000157030
iqck
IQ motif containing K
chr10_+_26813710 0.60 ENSDART00000136122
si:ch211-263p13.7
si:ch211-263p13.7
chr17_-_24364527 0.60 ENSDART00000155192
wdpcp
WD repeat containing planar cell polarity effector
chr2_-_27774783 0.59 ENSDART00000161864
XKR4
zgc:123035
chr14_-_5678457 0.59 ENSDART00000012116
tlx2
T cell leukemia homeobox 2
chr3_-_18792492 0.59 ENSDART00000134208
ENSDART00000034373
hagh
hydroxyacylglutathione hydrolase
chr8_-_13454281 0.57 ENSDART00000141959
CR354547.2

chr22_+_29009541 0.56 ENSDART00000169449
pimr97
Pim proto-oncogene, serine/threonine kinase, related 97
chr21_+_44112914 0.56 ENSDART00000062836
fgf1b
fibroblast growth factor 1b
chr2_+_46009507 0.56 ENSDART00000193596
CR762395.1

chr8_-_13486258 0.56 ENSDART00000137459
pimr104
Pim proto-oncogene, serine/threonine kinase, related 104
chr19_+_40856807 0.56 ENSDART00000139083
gngt1
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr11_+_37201483 0.55 ENSDART00000160930
ENSDART00000173439
ENSDART00000171273
zgc:112265
zgc:112265
chr3_-_62393449 0.55 ENSDART00000101870
ENSDART00000140782
ENSDART00000181704
proza
protein Z, vitamin K-dependent plasma glycoprotein a
chr19_-_5103313 0.55 ENSDART00000037007
tpi1a
triosephosphate isomerase 1a
chr22_-_18778988 0.55 ENSDART00000019235
atp5f1d
ATP synthase F1 subunit delta
chr17_+_23770848 0.54 ENSDART00000079646
kcnk18
potassium channel, subfamily K, member 18
chr19_-_5103141 0.54 ENSDART00000150952
tpi1a
triosephosphate isomerase 1a
chr8_+_25145464 0.54 ENSDART00000136505
gnai3
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
chr9_+_31795343 0.54 ENSDART00000139584
itgbl1
integrin, beta-like 1
chr4_-_17409533 0.53 ENSDART00000011943
pah
phenylalanine hydroxylase
chr20_+_16750177 0.52 ENSDART00000185357
calm1b
calmodulin 1b
chr25_+_1591964 0.52 ENSDART00000093277
ppm1h
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr9_-_22834860 0.52 ENSDART00000146486
neb
nebulin
chr6_-_43047774 0.52 ENSDART00000161722
glyctk
glycerate kinase
chr21_+_39432248 0.52 ENSDART00000179938
pafah1b1b
platelet-activating factor acetylhydrolase 1b, regulatory subunit 1b
chr22_-_18779232 0.51 ENSDART00000186726
atp5f1d
ATP synthase F1 subunit delta
chr4_+_2092683 0.50 ENSDART00000067423
frs2a
fibroblast growth factor receptor substrate 2a
chr17_+_26352372 0.49 ENSDART00000155177
grid1a
glutamate receptor, ionotropic, delta 1a
chr1_+_57331813 0.49 ENSDART00000152440
ENSDART00000062841
epn3b
epsin 3b
chr8_+_20679759 0.49 ENSDART00000088668
nfic
nuclear factor I/C
chr7_-_56793739 0.47 ENSDART00000082842
si:ch211-146m13.3
si:ch211-146m13.3
chr22_-_38258053 0.46 ENSDART00000132516
elavl2
ELAV like neuron-specific RNA binding protein 2
chr18_-_50956280 0.46 ENSDART00000058457
st7
suppression of tumorigenicity 7
chr20_+_11800063 0.45 ENSDART00000152230
si:ch211-155o21.4
si:ch211-155o21.4
chr20_+_6142433 0.44 ENSDART00000054084
ENSDART00000136986
ttr
transthyretin (prealbumin, amyloidosis type I)
chr5_-_3889047 0.43 ENSDART00000185817
mlxipl
MLX interacting protein like
chr18_+_14529005 0.42 ENSDART00000186379
kcng4a
potassium voltage-gated channel, subfamily G, member 4a
chr2_+_38264964 0.41 ENSDART00000182068
dhrs1
dehydrogenase/reductase (SDR family) member 1
chr16_-_19026414 0.41 ENSDART00000141208
pimr98
Pim proto-oncogene, serine/threonine kinase, related 98
chr22_-_17595310 0.40 ENSDART00000099056
gpx4a
glutathione peroxidase 4a
chr4_-_17629444 0.40 ENSDART00000108814
nrip2
nuclear receptor interacting protein 2
chr21_-_551014 0.40 ENSDART00000099252
vimr1
vimentin-related 1
chr2_-_22230326 0.40 ENSDART00000127810
fam110b
family with sequence similarity 110, member B
chr10_-_4980150 0.39 ENSDART00000093228
mat2al
methionine adenosyltransferase II, alpha-like
chr7_-_16034324 0.39 ENSDART00000002498
ENSDART00000162962
elp4
elongator acetyltransferase complex subunit 4
chr6_-_8498908 0.37 ENSDART00000149222
pglyrp2
peptidoglycan recognition protein 2
chr11_-_40257225 0.37 ENSDART00000139009
TRIM62 (1 of many)
si:ch211-193i15.2
chr5_-_41531629 0.36 ENSDART00000051082
akr1a1a
aldo-keto reductase family 1, member A1a (aldehyde reductase)
chr6_-_13376060 0.36 ENSDART00000104732
ENSDART00000125271
arl6ip6
ADP-ribosylation factor-like 6 interacting protein 6
chr14_+_46216703 0.36 ENSDART00000136045
ENSDART00000142317
mgst2
microsomal glutathione S-transferase 2
chr25_+_31929325 0.36 ENSDART00000181095
apba2a
amyloid beta (A4) precursor protein-binding, family A, member 2a
chr22_+_27284462 0.35 ENSDART00000164660
si:ch73-103b2.1
si:ch73-103b2.1
chr16_+_16978424 0.35 ENSDART00000143128
rpl18
ribosomal protein L18
chr13_+_15182149 0.35 ENSDART00000193644
ENSDART00000134421
ENSDART00000086281
mavs
mitochondrial antiviral signaling protein
chr17_-_43287290 0.35 ENSDART00000156885
EML5
si:dkey-1f12.3
chr11_+_37720756 0.35 ENSDART00000173337
snrpe
small nuclear ribonucleoprotein polypeptide E
chr5_-_9090178 0.35 ENSDART00000091472
kcnv2b
potassium channel, subfamily V, member 2b
chr24_+_3328354 0.35 ENSDART00000147468
bdh1
3-hydroxybutyrate dehydrogenase, type 1
chr22_+_28995391 0.34 ENSDART00000164486
pimr99
Pim proto-oncogene, serine/threonine kinase, related 99
chr25_-_16826219 0.32 ENSDART00000191299
ENSDART00000188504
dyrk4
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
chr7_-_16237861 0.32 ENSDART00000173647
btr07
bloodthirsty-related gene family, member 7
chr2_-_22286828 0.32 ENSDART00000168653
fam110b
family with sequence similarity 110, member B
chr16_-_46567344 0.31 ENSDART00000127721
si:dkey-152b24.7
si:dkey-152b24.7
chr16_+_6021908 0.31 ENSDART00000163786
BX511115.1

chr9_-_48281941 0.31 ENSDART00000099787
klhl41a
kelch-like family member 41a
chr5_-_16405651 0.31 ENSDART00000163942
slc39a14
solute carrier family 39 (zinc transporter), member 14
chr21_+_37355716 0.31 ENSDART00000131188
nsd1b
nuclear receptor binding SET domain protein 1b
chr10_+_28428222 0.30 ENSDART00000135003
si:ch211-222e20.4
si:ch211-222e20.4
chr8_+_48095911 0.30 ENSDART00000138717
si:ch211-263k4.2
si:ch211-263k4.2
chr6_+_27418541 0.30 ENSDART00000187410
crocc2
ciliary rootlet coiled-coil, rootletin family member 2
chr16_+_27345383 0.30 ENSDART00000078250
ENSDART00000162857
nr4a3
nuclear receptor subfamily 4, group A, member 3
chr8_+_24740013 0.30 ENSDART00000126897
lamtor5
late endosomal/lysosomal adaptor, MAPK and MTOR activator 5
chr13_-_22862133 0.29 ENSDART00000138563
pbld2
phenazine biosynthesis-like protein domain containing 2
chr23_+_42336084 0.29 ENSDART00000158959
ENSDART00000161812
cyp2aa7
cyp2aa8
cytochrome P450, family 2, subfamily AA, polypeptide 7
cytochrome P450, family 2, subfamily AA, polypeptide 8
chr14_+_6159162 0.29 ENSDART00000128638
bscl2l
Bernardinelli-Seip congenital lipodystrophy 2, like
chr3_+_22442445 0.29 ENSDART00000190921
wnk4b
WNK lysine deficient protein kinase 4b
chr25_-_19090479 0.28 ENSDART00000027465
ENSDART00000177670
cacna2d4b
calcium channel, voltage-dependent, alpha 2/delta subunit 4b
chr5_+_69868911 0.28 ENSDART00000014649
ENSDART00000188215
ENSDART00000167385
ugt2a5
UDP glucuronosyltransferase 2 family, polypeptide A5
chr22_-_24967348 0.28 ENSDART00000153490
ENSDART00000084871
fam20cl
family with sequence similarity 20, member C like
chr19_+_30387999 0.28 ENSDART00000145396
tspan13b
tetraspanin 13b
chr15_-_31514818 0.27 ENSDART00000153978
hmgb1b
high mobility group box 1b
chr4_+_8680767 0.27 ENSDART00000182726
adipor2
adiponectin receptor 2
chr7_+_26100024 0.27 ENSDART00000173726
si:ch211-196f2.3
si:ch211-196f2.3
chr15_+_1004680 0.27 ENSDART00000157310
si:dkey-77f5.8
si:dkey-77f5.8
chr11_+_37720552 0.27 ENSDART00000050296
ENSDART00000172867
snrpe
small nuclear ribonucleoprotein polypeptide E
chr5_+_1079423 0.27 ENSDART00000172231
si:zfos-128g4.2
si:zfos-128g4.2
chr10_-_35220285 0.27 ENSDART00000180439
ypel2a
yippee-like 2a
chr4_-_23839789 0.27 ENSDART00000143571
usp6nl
USP6 N-terminal like
chr12_+_28799988 0.26 ENSDART00000022724
pnpo
pyridoxamine 5'-phosphate oxidase
chr18_+_17959681 0.26 ENSDART00000142700
znf423
zinc finger protein 423
chr21_-_22831388 0.26 ENSDART00000151040
angptl5
angiopoietin-like 5
chr15_+_24644251 0.26 ENSDART00000181660
smtnl
smoothelin, like
chr2_-_31634978 0.26 ENSDART00000135668
si:ch211-106h4.9
si:ch211-106h4.9
chr2_+_27010439 0.26 ENSDART00000030547
cdh7a
cadherin 7a
chr15_-_30815826 0.25 ENSDART00000156160
ENSDART00000145918
msi2b
musashi RNA-binding protein 2b
chr5_+_37290260 0.25 ENSDART00000113642
zgc:163098
zgc:163098
chr3_+_29458517 0.24 ENSDART00000134258
grap2a
GRB2-related adaptor protein 2a
chr12_+_4573696 0.24 ENSDART00000152534
si:dkey-94f20.4
si:dkey-94f20.4
chr3_-_15080226 0.24 ENSDART00000109818
ENSDART00000139835
nme4
NME/NM23 nucleoside diphosphate kinase 4
chr20_+_26095530 0.23 ENSDART00000139350
syne1a
spectrin repeat containing, nuclear envelope 1a
chr20_+_36682051 0.23 ENSDART00000130513
ncoa1
nuclear receptor coactivator 1
chr18_+_13315739 0.23 ENSDART00000143404
si:ch211-260p9.3
si:ch211-260p9.3
chr14_-_25111496 0.23 ENSDART00000158108
si:rp71-1d10.8
si:rp71-1d10.8
chr12_-_7806007 0.23 ENSDART00000190359
ank3b
ankyrin 3b
chr7_+_48806420 0.22 ENSDART00000083431
cpt1aa
carnitine palmitoyltransferase 1Aa (liver)
chr13_+_22480496 0.22 ENSDART00000136863
ENSDART00000131870
ENSDART00000078720
ENSDART00000078740
ENSDART00000139218
ldb3a
LIM domain binding 3a
chr2_+_38608290 0.22 ENSDART00000159066
cdh24b
cadherin 24, type 2b
chr6_+_18569453 0.22 ENSDART00000171338
rhot1b
ras homolog family member T1
chr13_+_22480857 0.22 ENSDART00000078721
ENSDART00000044719
ENSDART00000130957
ENSDART00000078757
ENSDART00000130424
ENSDART00000078747
ldb3a
LIM domain binding 3a
chr25_-_29415369 0.22 ENSDART00000110774
ENSDART00000019183
ugt5a2
ugt5a1
UDP glucuronosyltransferase 5 family, polypeptide A2
UDP glucuronosyltransferase 5 family, polypeptide A1
chr21_+_5932140 0.21 ENSDART00000193767
rexo4
REX4 homolog, 3'-5' exonuclease
chr21_-_2958422 0.21 ENSDART00000174091
zgc:194215
zgc:194215
chr19_-_14155781 0.19 ENSDART00000169232
nr0b2b
nuclear receptor subfamily 0, group B, member 2b
chr15_+_44133972 0.19 ENSDART00000157846
ENSDART00000191082
CU655961.2

chr3_+_155659 0.19 ENSDART00000183570
FP326649.2

chr7_-_41338923 0.19 ENSDART00000099138
ncf2
neutrophil cytosolic factor 2
chr9_-_27749936 0.19 ENSDART00000064156
tbccd1
TBCC domain containing 1
chr6_+_52804267 0.19 ENSDART00000065681
matn4
matrilin 4
chr17_-_12196865 0.18 ENSDART00000154694
kif28
kinesin family member 28
chr21_+_32332616 0.18 ENSDART00000154105
si:ch211-247j9.1
si:ch211-247j9.1
chr6_-_8498676 0.18 ENSDART00000148627
pglyrp2
peptidoglycan recognition protein 2
chr25_-_1687481 0.18 ENSDART00000163553
ENSDART00000179460
mon2
MON2 homolog, regulator of endosome-to-Golgi trafficking
chr17_-_51224800 0.18 ENSDART00000150089
psen1
presenilin 1
chr16_-_17116499 0.18 ENSDART00000138983
si:dkey-260g12.1
si:dkey-260g12.1
chr2_-_47431205 0.17 ENSDART00000014350
ENSDART00000038828
pax3a
paired box 3a
chr22_+_10163901 0.17 ENSDART00000190468
rpp14
ribonuclease P/MRP 14 subunit
chr20_+_6543674 0.17 ENSDART00000134204
tns3.1
tensin 3, tandem duplicate 1
chr7_-_35708450 0.17 ENSDART00000193886
irx5a
iroquois homeobox 5a
chr12_-_29301022 0.17 ENSDART00000187826
sh2d4bb
SH2 domain containing 4Bb
chr21_-_20939488 0.16 ENSDART00000039043
rgs7bpb
regulator of G protein signaling 7 binding protein b
chr12_+_46708920 0.16 ENSDART00000153089
exoc7
exocyst complex component 7
chr21_+_28724099 0.16 ENSDART00000138017
puraa
purine-rich element binding protein Aa
chr21_-_29100110 0.16 ENSDART00000142598
timd4
T cell immunoglobulin and mucin domain containing 4
chr19_-_8732037 0.15 ENSDART00000138971
si:ch211-39a7.1
si:ch211-39a7.1
chr12_+_3912544 0.15 ENSDART00000013465
tbx6
T-box 6
chr21_+_5801105 0.15 ENSDART00000151225
ENSDART00000184487
ccng2
cyclin G2
chr13_-_15994419 0.15 ENSDART00000079724
ENSDART00000042377
ENSDART00000046079
ENSDART00000050481
ENSDART00000016430
ikzf1
IKAROS family zinc finger 1 (Ikaros)
chr3_+_41922114 0.14 ENSDART00000138280
lfng
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr16_-_40727455 0.13 ENSDART00000162331
si:dkey-22o22.2
si:dkey-22o22.2

Network of associatons between targets according to the STRING database.

First level regulatory network of rarga

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 4.0 GO:0061333 renal tubule morphogenesis(GO:0061333) nephron tubule morphogenesis(GO:0072078) nephron epithelium morphogenesis(GO:0072088)
0.3 1.1 GO:0019242 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.2 0.6 GO:0006089 lactate metabolic process(GO:0006089)
0.2 0.6 GO:0098543 detection of biotic stimulus(GO:0009595) detection of bacterium(GO:0016045) detection of other organism(GO:0098543) detection of external biotic stimulus(GO:0098581)
0.2 1.1 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.2 0.6 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.2 1.1 GO:0046292 formaldehyde metabolic process(GO:0046292) formaldehyde catabolic process(GO:0046294)
0.2 0.8 GO:0043570 maintenance of DNA repeat elements(GO:0043570)
0.1 0.5 GO:0051012 microtubule sliding(GO:0051012)
0.1 0.8 GO:0048745 smooth muscle tissue development(GO:0048745)
0.1 0.9 GO:0046546 development of primary male sexual characteristics(GO:0046546)
0.1 0.6 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.1 0.3 GO:0033212 iron assimilation(GO:0033212)
0.1 0.3 GO:0070294 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.1 0.3 GO:0042822 water-soluble vitamin biosynthetic process(GO:0042364) pyridoxal phosphate metabolic process(GO:0042822) pyridoxal phosphate biosynthetic process(GO:0042823)
0.1 0.5 GO:0071691 cardiac muscle thin filament assembly(GO:0071691)
0.1 0.8 GO:0032096 negative regulation of response to food(GO:0032096) negative regulation of appetite(GO:0032099)
0.1 0.7 GO:1902262 apoptotic process involved in patterning of blood vessels(GO:1902262)
0.1 0.8 GO:0040014 regulation of multicellular organism growth(GO:0040014)
0.1 0.6 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.1 0.4 GO:0019370 leukotriene metabolic process(GO:0006691) leukotriene biosynthetic process(GO:0019370)
0.1 0.7 GO:0070475 rRNA base methylation(GO:0070475)
0.1 0.4 GO:0039528 cytoplasmic pattern recognition receptor signaling pathway in response to virus(GO:0039528) cellular response to virus(GO:0098586)
0.1 0.3 GO:0070166 enamel mineralization(GO:0070166)
0.1 0.4 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.1 1.6 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.1 1.1 GO:0097324 melanocyte migration(GO:0097324)
0.1 1.1 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471)
0.0 0.7 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.2 GO:0045730 respiratory burst(GO:0045730)
0.0 0.2 GO:0051661 Golgi localization(GO:0051645) maintenance of centrosome location(GO:0051661)
0.0 0.2 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.0 0.5 GO:1902222 L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.0 0.2 GO:0051563 smooth endoplasmic reticulum calcium ion homeostasis(GO:0051563)
0.0 1.0 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.0 0.2 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.0 0.3 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.7 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.5 GO:0030324 respiratory tube development(GO:0030323) lung development(GO:0030324)
0.0 0.1 GO:0055016 hypochord development(GO:0055016)
0.0 0.1 GO:0002369 T cell cytokine production(GO:0002369)
0.0 0.6 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.4 GO:0042572 retinol metabolic process(GO:0042572)
0.0 0.1 GO:0099551 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551) cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.0 0.3 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.0 0.1 GO:0030091 protein repair(GO:0030091)
0.0 0.1 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.0 0.2 GO:1900027 regulation of ruffle assembly(GO:1900027)
0.0 10.7 GO:0046777 protein autophosphorylation(GO:0046777)
0.0 0.1 GO:0090386 phagosome maturation involved in apoptotic cell clearance(GO:0090386) phagolysosome assembly involved in apoptotic cell clearance(GO:0090387)
0.0 0.3 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.0 0.1 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.0 0.2 GO:0021523 somatic motor neuron differentiation(GO:0021523)
0.0 0.3 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.0 0.7 GO:0097194 execution phase of apoptosis(GO:0097194)
0.0 0.1 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.2 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998)
0.0 0.5 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.6 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.1 GO:0071267 L-methionine biosynthetic process from methylthioadenosine(GO:0019509) amino acid salvage(GO:0043102) L-methionine biosynthetic process(GO:0071265) L-methionine salvage(GO:0071267)
0.0 0.3 GO:0046549 retinal cone cell development(GO:0046549)
0.0 1.2 GO:0006119 oxidative phosphorylation(GO:0006119)
0.0 0.3 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.0 0.4 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 0.3 GO:0021772 olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988)
0.0 0.2 GO:0072498 embryonic skeletal joint development(GO:0072498)
0.0 0.5 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.0 0.2 GO:0050936 xanthophore differentiation(GO:0050936)
0.0 0.1 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.0 0.2 GO:0006228 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.0 0.5 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.2 GO:0047497 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497) establishment of mitochondrion localization(GO:0051654)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0032301 MutSalpha complex(GO:0032301)
0.2 0.9 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.2 0.6 GO:0034709 methylosome(GO:0034709)
0.2 0.6 GO:0097541 axonemal basal plate(GO:0097541)
0.2 0.9 GO:0071439 clathrin complex(GO:0071439)
0.1 0.5 GO:0008247 1-alkyl-2-acetylglycerophosphocholine esterase complex(GO:0008247)
0.1 1.7 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.1 0.5 GO:0035253 ciliary rootlet(GO:0035253)
0.1 0.7 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.3 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.7 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.4 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.1 GO:1990923 PET complex(GO:1990923)
0.0 0.2 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.2 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.1 GO:0034359 mature chylomicron(GO:0034359)
0.0 0.1 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 1.1 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.7 GO:0032040 small-subunit processome(GO:0032040)
0.0 1.2 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.2 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 1.1 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.1 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 1.1 GO:0005814 centriole(GO:0005814)
0.0 0.6 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.8 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.2 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.5 GO:0030125 clathrin vesicle coat(GO:0030125)
0.0 0.5 GO:0008305 integrin complex(GO:0008305)
0.0 1.0 GO:0030018 Z disc(GO:0030018)
0.0 0.5 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.2 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.3 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.3 1.1 GO:0008929 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
0.3 0.8 GO:0032404 guanine/thymine mispair binding(GO:0032137) single base insertion or deletion binding(GO:0032138) single thymine insertion binding(GO:0032143) oxidized DNA binding(GO:0032356) oxidized purine DNA binding(GO:0032357) mismatch repair complex binding(GO:0032404) MutLalpha complex binding(GO:0032405)
0.2 1.1 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024) S-(hydroxymethyl)glutathione dehydrogenase activity(GO:0051903)
0.2 0.6 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.2 0.6 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.1 0.7 GO:0070004 cysteine-type exopeptidase activity(GO:0070004)
0.1 0.5 GO:0008887 glycerate kinase activity(GO:0008887)
0.1 0.4 GO:0070324 thyroid hormone binding(GO:0070324)
0.1 0.3 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086)
0.1 0.7 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 0.4 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
0.1 1.1 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.1 0.4 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.1 0.9 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 1.7 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 0.4 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.1 0.4 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.1 1.2 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1 0.9 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 0.8 GO:0031994 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
0.1 0.9 GO:0032051 clathrin light chain binding(GO:0032051)
0.1 0.5 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.1 0.7 GO:0045503 dynein light chain binding(GO:0045503)
0.0 0.6 GO:0070739 protein-glutamic acid ligase activity(GO:0070739) tubulin-glutamic acid ligase activity(GO:0070740)
0.0 1.2 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.7 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.0 0.5 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.5 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.1 GO:0060175 brain-derived neurotrophic factor binding(GO:0048403) brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.0 0.5 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.0 0.2 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 0.1 GO:0033745 L-methionine-(R)-S-oxide reductase activity(GO:0033745)
0.0 0.6 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.3 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.2 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.4 GO:0051371 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.0 0.2 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.2 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.5 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.3 GO:0019869 chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.0 0.5 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.3 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.1 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0 0.1 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.1 GO:0034584 piRNA binding(GO:0034584)
0.0 0.4 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.2 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.1 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.1 GO:0070325 low-density lipoprotein particle receptor binding(GO:0050750) lipoprotein particle receptor binding(GO:0070325)
0.0 0.3 GO:0010181 FMN binding(GO:0010181)
0.0 2.4 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 10.0 GO:0004674 protein serine/threonine kinase activity(GO:0004674)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.1 1.2 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.5 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.6 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.5 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.8 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.3 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.2 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.2 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.3 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.7 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.1 1.2 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 0.5 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 0.9 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 0.6 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.5 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 0.4 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.4 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 1.2 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.5 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.4 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.2 REACTOME SIGNALING BY NOTCH4 Genes involved in Signaling by NOTCH4
0.0 0.2 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.2 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.2 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.7 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.2 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis