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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for rbpjb

Z-value: 0.67

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Transcription factors associated with rbpjb

Gene Symbol Gene ID Gene Info
rbpjb
ENSDARG00000052091 recombination signal binding protein for immunoglobulin kappa J region b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
rbpjbdr11_v1_chr7_+_62080456_620804560.805.7e-05Click!

Activity profile of rbpjb motif

Sorted Z-values of rbpjb motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr8_-_18899427 1.63 ENSDART00000079840
rorca
RAR-related orphan receptor C a
chr1_+_14454663 1.42 ENSDART00000005067
rbpja
recombination signal binding protein for immunoglobulin kappa J region a
chr1_-_31105376 1.29 ENSDART00000132466
ppp1r9alb
protein phosphatase 1 regulatory subunit 9A-like B
chr6_+_10333920 1.14 ENSDART00000151667
ENSDART00000151477
cobll1a
cordon-bleu WH2 repeat protein-like 1a
chr21_-_13690712 1.10 ENSDART00000065817
pou5f3
POU domain, class 5, transcription factor 3
chr13_-_33654931 1.09 ENSDART00000020350
snx5
sorting nexin 5
chr20_+_14789148 1.03 ENSDART00000164761
tmed5
transmembrane p24 trafficking protein 5
chr19_-_27830818 0.93 ENSDART00000131767
papd7
PAP associated domain containing 7
chr15_-_31147301 0.91 ENSDART00000157145
ENSDART00000155473
ENSDART00000048103
ksr1b
kinase suppressor of ras 1b
chr5_-_23675222 0.86 ENSDART00000135153
TBC1D8B
si:dkey-110k5.6
chr14_+_28486213 0.83 ENSDART00000161852
stag2b
stromal antigen 2b
chr6_+_3716666 0.83 ENSDART00000041627
ssb
Sjogren syndrome antigen B (autoantigen La)
chr2_+_2110271 0.83 ENSDART00000148460
dspa
desmoplakin a
chr6_-_53144336 0.80 ENSDART00000154429
gnai2b
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2b
chr4_-_13613148 0.77 ENSDART00000067164
ENSDART00000111247
irf5
interferon regulatory factor 5
chr21_-_4849029 0.77 ENSDART00000168930
ENSDART00000151019
notch1a
notch 1a
chr20_+_14789305 0.75 ENSDART00000002463
tmed5
transmembrane p24 trafficking protein 5
chr8_+_14915332 0.74 ENSDART00000164385
abl2
c-abl oncogene 2, non-receptor tyrosine kinase
chr19_-_25113660 0.73 ENSDART00000035538
ptp4a3
protein tyrosine phosphatase type IVA, member 3
chr8_-_18613948 0.73 ENSDART00000089172
cpox
coproporphyrinogen oxidase
chr7_+_62080456 0.70 ENSDART00000092580
rbpjb
recombination signal binding protein for immunoglobulin kappa J region b
chr16_+_33953644 0.70 ENSDART00000164447
ENSDART00000159969
arid1aa
AT rich interactive domain 1Aa (SWI-like)
chr9_-_23807032 0.68 ENSDART00000027443
esyt3
extended synaptotagmin-like protein 3
chr21_-_27213166 0.68 ENSDART00000146959
mark2a
MAP/microtubule affinity-regulating kinase 2a
chr11_+_34921492 0.62 ENSDART00000128070
gnai2a
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2a
chr6_-_9695294 0.61 ENSDART00000162728
nop58
NOP58 ribonucleoprotein homolog (yeast)
chr20_-_32045057 0.60 ENSDART00000152970
ENSDART00000034248
rab32a
RAB32a, member RAS oncogene family
chr18_+_14277003 0.60 ENSDART00000006628
zgc:173742
zgc:173742
chr18_+_22220656 0.59 ENSDART00000191862
ripor1
RHO family interacting cell polarization regulator 1
chr23_-_36303216 0.59 ENSDART00000188720
cbx5
chromobox homolog 5 (HP1 alpha homolog, Drosophila)
chr21_+_31253048 0.57 ENSDART00000178521
ENSDART00000132317
ENSDART00000040190
asl
argininosuccinate lyase
chr9_+_2020667 0.57 ENSDART00000157818
lnpa
limb and neural patterns a
chr3_-_34547000 0.56 ENSDART00000166623
sept9a
septin 9a
chr20_-_38801981 0.55 ENSDART00000125333
cad
carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
chr12_+_38563073 0.55 ENSDART00000009172
ttyh2
tweety family member 2
chr24_-_6375774 0.54 ENSDART00000013294
anxa13
annexin A13
chr4_-_4250317 0.54 ENSDART00000103316
cd9b
CD9 molecule b
chr19_-_11015238 0.53 ENSDART00000010997
tpm3
tropomyosin 3
chr5_+_25736979 0.53 ENSDART00000175959
abhd17b
abhydrolase domain containing 17B
chr8_+_21225064 0.52 ENSDART00000129210
cry1ba
cryptochrome circadian clock 1ba
chr23_-_21758253 0.52 ENSDART00000046613
vps13d
vacuolar protein sorting 13 homolog D (S. cerevisiae)
chr1_+_10018466 0.51 ENSDART00000113551
trim2b
tripartite motif containing 2b
chr18_-_16953978 0.50 ENSDART00000100126
akip1
A kinase (PRKA) interacting protein 1
chr22_-_11054244 0.50 ENSDART00000105823
insrb
insulin receptor b
chr7_+_52712807 0.48 ENSDART00000174095
ENSDART00000174377
ENSDART00000174061
ENSDART00000174094
ENSDART00000110906
ENSDART00000174071
ENSDART00000174238
znf280d
zinc finger protein 280D
chr1_-_46924801 0.48 ENSDART00000142560
pdxkb
pyridoxal (pyridoxine, vitamin B6) kinase b
chr13_-_31389661 0.48 ENSDART00000134630
zdhhc16a
zinc finger, DHHC-type containing 16a
chr9_+_19623363 0.46 ENSDART00000142471
ENSDART00000147662
ENSDART00000136053
pdxka
pyridoxal (pyridoxine, vitamin B6) kinase a
chr5_-_36597612 0.46 ENSDART00000031270
ENSDART00000122098
rhogc
ras homolog gene family, member Gc
chr13_-_36798204 0.46 ENSDART00000012357
sav1
salvador family WW domain containing protein 1
chr19_+_40248697 0.45 ENSDART00000151269
cdk6
cyclin-dependent kinase 6
chr2_-_57941037 0.44 ENSDART00000131420
si:dkeyp-68b7.5
si:dkeyp-68b7.5
chr3_+_31058464 0.44 ENSDART00000153381
si:dkey-66i24.7
si:dkey-66i24.7
chr15_-_47468085 0.43 ENSDART00000164438
inppl1a
inositol polyphosphate phosphatase-like 1a
chr20_+_45620076 0.43 ENSDART00000113806
hnrnpa0l
heterogeneous nuclear ribonucleoprotein A0, like
chr5_+_33287611 0.42 ENSDART00000125093
ENSDART00000146759
med22
mediator complex subunit 22
chr10_+_17026870 0.42 ENSDART00000184529
ENSDART00000157480
CR855996.2

chr3_+_46315016 0.42 ENSDART00000157199
mkl2b
MKL/myocardin-like 2b
chr14_+_49152341 0.42 ENSDART00000084114
nsd1a
nuclear receptor binding SET domain protein 1a
chr8_+_48947608 0.41 ENSDART00000184742
rer1
retention in endoplasmic reticulum sorting receptor 1
chr25_+_20272145 0.39 ENSDART00000109605
si:dkey-219c3.2
si:dkey-219c3.2
chr17_+_49081828 0.39 ENSDART00000156492
tiam2a
T cell lymphoma invasion and metastasis 2a
chr21_+_43485512 0.38 ENSDART00000026666
atg4a
autophagy related 4A, cysteine peptidase
chr16_-_21047872 0.38 ENSDART00000131582
cbx3b
chromobox homolog 3b
chr11_-_11518469 0.37 ENSDART00000104254
krt15
keratin 15
chr19_-_7540821 0.37 ENSDART00000143958
lix1l
limb and CNS expressed 1 like
chr23_-_36003441 0.37 ENSDART00000164699
calcoco1a
calcium binding and coiled-coil domain 1a
chr15_+_20530649 0.36 ENSDART00000186312
tnfaip1
tumor necrosis factor, alpha-induced protein 1 (endothelial)
chr3_+_27722355 0.36 ENSDART00000132761
arhgdig
Rho GDP dissociation inhibitor (GDI) gamma
chr24_+_31374324 0.35 ENSDART00000172335
ENSDART00000163162
cpne3
copine III
chr25_-_893464 0.35 ENSDART00000159321
znf609a
zinc finger protein 609a
chr23_-_36003282 0.35 ENSDART00000103150
calcoco1a
calcium binding and coiled-coil domain 1a
chr5_+_61467618 0.35 ENSDART00000074073
ENSDART00000182094
alkbh4
alkB homolog 4, lysine demthylase
chr7_+_27834130 0.35 ENSDART00000052656
rras2
RAS related 2
chr6_+_30430591 0.34 ENSDART00000108943
shroom2a
shroom family member 2a
chr24_+_28953089 0.34 ENSDART00000153761
rnpc3
RNA-binding region (RNP1, RRM) containing 3
chr13_+_15657911 0.33 ENSDART00000134972
ENSDART00000138991
ENSDART00000133342
mark3a
MAP/microtubule affinity-regulating kinase 3a
chr13_-_24874950 0.33 ENSDART00000077775
kat6b
K(lysine) acetyltransferase 6B
chr12_-_13729263 0.32 ENSDART00000078021
foxh1
forkhead box H1
chr12_+_1286642 0.32 ENSDART00000157467
pemt
phosphatidylethanolamine N-methyltransferase
chr16_-_21047483 0.32 ENSDART00000136235
cbx3b
chromobox homolog 3b
chr23_+_32011768 0.31 ENSDART00000053509
plagx
pleiomorphic adenoma gene X
chr20_+_22799857 0.31 ENSDART00000058527
scfd2
sec1 family domain containing 2
chr13_-_33700461 0.30 ENSDART00000160520
mad2l1bp
MAD2L1 binding protein
chr13_-_33246154 0.30 ENSDART00000130127
rtf1
RTF1 homolog, Paf1/RNA polymerase II complex component
chr10_+_35329751 0.30 ENSDART00000148043
si:dkey-259j3.5
si:dkey-259j3.5
chr3_-_41995321 0.29 ENSDART00000192277
ttyh3a
tweety family member 3a
chr5_-_22082918 0.29 ENSDART00000020908
zc4h2
zinc finger, C4H2 domain containing
chr20_+_22799641 0.28 ENSDART00000131132
scfd2
sec1 family domain containing 2
chr10_-_42297889 0.28 ENSDART00000099262
tcf7l1a
transcription factor 7 like 1a
chr8_+_26396552 0.28 ENSDART00000087151
amt
aminomethyltransferase
chr24_-_20658446 0.28 ENSDART00000127923
nktr
natural killer cell triggering receptor
chr5_+_20035284 0.27 ENSDART00000191808
sgsm1a
small G protein signaling modulator 1a
chr6_-_12172424 0.27 ENSDART00000109344
tanc1a
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1a
chr14_+_41406321 0.27 ENSDART00000111480
bcorl1
BCL6 corepressor-like 1
chr23_+_25172682 0.27 ENSDART00000191197
ENSDART00000183497
si:dkey-151g10.3
si:dkey-151g10.3
chr8_-_11067079 0.27 ENSDART00000181986
dennd2c
DENN/MADD domain containing 2C
chr25_+_6122823 0.25 ENSDART00000191824
ENSDART00000067514
rbpms2a
RNA binding protein with multiple splicing 2a
chr19_+_24896409 0.24 ENSDART00000049840
eya3
EYA transcriptional coactivator and phosphatase 3
chr18_+_15644559 0.24 ENSDART00000061794
nr1h4
nuclear receptor subfamily 1, group H, member 4
chr25_+_35304903 0.24 ENSDART00000034313
ENSDART00000187659
gas2a
growth arrest-specific 2a
chr8_-_48847772 0.24 ENSDART00000122458
wrap73
WD repeat containing, antisense to TP73
chr24_-_19718077 0.24 ENSDART00000109107
ENSDART00000056082
csrnp1b
cysteine-serine-rich nuclear protein 1b
chr21_-_40562705 0.24 ENSDART00000158289
ENSDART00000171997
taok1b
TAO kinase 1b
chr9_+_38481780 0.23 ENSDART00000087241
lss
lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
chr16_-_9869056 0.23 ENSDART00000149312
ncalda
neurocalcin delta a
chr2_+_31957554 0.23 ENSDART00000012413
ankhb
ANKH inorganic pyrophosphate transport regulator b
chr21_-_43485351 0.23 ENSDART00000151597
ankrd46a
ankyrin repeat domain 46a
chr19_+_40322912 0.23 ENSDART00000146893
cdk6
cyclin-dependent kinase 6
chr17_-_49339677 0.23 ENSDART00000047857
orc3
origin recognition complex, subunit 3
chr2_+_1881334 0.22 ENSDART00000161420
adgrl2b.1
adhesion G protein-coupled receptor L2b, tandem duplicate 1
chr13_-_31017960 0.22 ENSDART00000145287
wdfy4
WDFY family member 4
chr22_+_12431608 0.22 ENSDART00000108609
rnd3a
Rho family GTPase 3a
chr25_-_14637660 0.21 ENSDART00000143666
nav2b
neuron navigator 2b
chr2_-_898899 0.21 ENSDART00000058289
dusp22b
dual specificity phosphatase 22b
chr1_+_1941031 0.20 ENSDART00000110331
PTGFRN
si:ch211-132g1.7
chr3_+_35608385 0.20 ENSDART00000193219
ENSDART00000132703
traf7
TNF receptor-associated factor 7
chr8_-_15150131 0.19 ENSDART00000138253
bcar3
BCAR3, NSP family adaptor protein
chr6_-_14292307 0.18 ENSDART00000177852
ENSDART00000061745
inpp4ab
inositol polyphosphate-4-phosphatase type I Ab
chr16_-_13881139 0.18 ENSDART00000138904
ENSDART00000090221
ENSDART00000135099
cdc42ep5
CDC42 effector protein (Rho GTPase binding) 5
chr24_-_24796583 0.18 ENSDART00000144791
ENSDART00000146570
pde7a
phosphodiesterase 7A
chr5_-_2112030 0.17 ENSDART00000091932
gusb
glucuronidase, beta
chr6_+_55006686 0.17 ENSDART00000081703
nav1b
neuron navigator 1b
chr13_+_11440389 0.16 ENSDART00000186463
zbtb18
zinc finger and BTB domain containing 18
chr4_+_4849789 0.16 ENSDART00000130818
ENSDART00000127751
ptprz1b
protein tyrosine phosphatase, receptor-type, Z polypeptide 1b
chr4_-_15103646 0.15 ENSDART00000138183
ENSDART00000181044
nrf1
nuclear respiratory factor 1
chr5_-_69312533 0.15 ENSDART00000082614
ENSDART00000183098
smtnb
smoothelin b
chr22_+_20141528 0.15 ENSDART00000187770
eef2a.1
eukaryotic translation elongation factor 2a, tandem duplicate 1
chr6_+_58522557 0.15 ENSDART00000128062
arfrp1
ADP-ribosylation factor related protein 1
chr18_+_6558146 0.15 ENSDART00000169401
b4galnt3b
beta-1,4-N-acetyl-galactosaminyl transferase 3b
chr19_-_12648408 0.15 ENSDART00000103692
fam210aa
family with sequence similarity 210, member Aa
chr25_+_10793478 0.15 ENSDART00000058339
ENSDART00000134923
ap3s2
adaptor-related protein complex 3, sigma 2 subunit
chr7_-_15185811 0.14 ENSDART00000031049
si:dkey-172h23.2
si:dkey-172h23.2
chr6_+_58522738 0.14 ENSDART00000157327
arfrp1
ADP-ribosylation factor related protein 1
chr6_+_21062416 0.14 ENSDART00000141643
si:dkey-91f15.1
si:dkey-91f15.1
chr5_+_62009765 0.14 ENSDART00000134335
akap10
A kinase (PRKA) anchor protein 10
chr12_+_21299338 0.13 ENSDART00000074540
ENSDART00000133188
ca10a
carbonic anhydrase Xa
chr6_-_25384526 0.13 ENSDART00000160544
PKN2 (1 of many)
zgc:153916
chr14_+_23076207 0.12 ENSDART00000161628
enox2
ecto-NOX disulfide-thiol exchanger 2
chr25_+_6186823 0.11 ENSDART00000153526
oaz2a
ornithine decarboxylase antizyme 2a
chr17_-_27235797 0.11 ENSDART00000130080
asap3
ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
chr7_+_38770167 0.11 ENSDART00000190827
arhgap1
Rho GTPase activating protein 1
chr5_-_25072607 0.11 ENSDART00000145061
pnpla7b
patatin-like phospholipase domain containing 7b
chr4_+_74943111 0.11 ENSDART00000004739
nup50
nucleoporin 50
chr5_+_62009930 0.10 ENSDART00000082872
akap10
A kinase (PRKA) anchor protein 10
chr1_-_51720633 0.10 ENSDART00000045894
rnaseh2a
ribonuclease H2, subunit A
chr3_-_40136743 0.09 ENSDART00000149546
myo15aa
myosin XVAa
chr18_+_26829086 0.09 ENSDART00000098356
slc28a1
solute carrier family 28 (concentrative nucleoside transporter), member 1
chr6_-_25384792 0.09 ENSDART00000169030
PKN2 (1 of many)
zgc:153916
chr17_-_27223965 0.09 ENSDART00000192577
asap3
ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
chr17_+_24851951 0.09 ENSDART00000180746
cx35.4
connexin 35.4
chr11_-_1409236 0.08 ENSDART00000121537
si:ch211-266k22.6
si:ch211-266k22.6
chr11_-_27962757 0.08 ENSDART00000147386
ece1
endothelin converting enzyme 1
chr5_+_38837429 0.08 ENSDART00000160236
fras1
Fraser extracellular matrix complex subunit 1
chr7_-_26436436 0.08 ENSDART00000019035
ENSDART00000123395
her8a
hairy-related 8a
chr11_-_7320211 0.08 ENSDART00000091664
apc2
adenomatosis polyposis coli 2
chr8_-_13010011 0.08 ENSDART00000140969
dennd2da
DENN/MADD domain containing 2Da
chr6_+_39923052 0.08 ENSDART00000149019
itpr1a
inositol 1,4,5-trisphosphate receptor, type 1a
chr9_-_12574473 0.08 ENSDART00000191372
ENSDART00000193667
igf2bp2a
insulin-like growth factor 2 mRNA binding protein 2a
chr18_-_11184584 0.06 ENSDART00000040500
tspan9a
tetraspanin 9a
chr9_-_7089303 0.06 ENSDART00000146609
coa5
cytochrome C oxidase assembly factor 5
chr17_-_27200634 0.05 ENSDART00000185332
asap3
ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
chr7_+_53754653 0.05 ENSDART00000163261
ENSDART00000158160
neo1a
neogenin 1a
chr3_+_59051503 0.05 ENSDART00000160767
rasd4
rasd family member 4
chr19_-_12648122 0.05 ENSDART00000151184
fam210aa
family with sequence similarity 210, member Aa
chr7_+_53755054 0.05 ENSDART00000181629
neo1a
neogenin 1a
chr18_+_26829362 0.05 ENSDART00000132728
slc28a1
solute carrier family 28 (concentrative nucleoside transporter), member 1
chr1_+_54683655 0.04 ENSDART00000132785
knop1
lysine-rich nucleolar protein 1
chr10_+_3507861 0.04 ENSDART00000092684
rph3aa
rabphilin 3A homolog (mouse), a
chr16_-_52646789 0.04 ENSDART00000035761
ubr5
ubiquitin protein ligase E3 component n-recognin 5
chr8_+_21159122 0.04 ENSDART00000033491
spryd4
SPRY domain containing 4
chr1_-_40016058 0.04 ENSDART00000165373
cdk2ap2
cyclin-dependent kinase 2 associated protein 2
chr9_-_22205682 0.03 ENSDART00000101869
crygm2d12
crystallin, gamma M2d12
chr21_-_2621127 0.03 ENSDART00000172363
col4a3bpb
collagen, type IV, alpha 3 (Goodpasture antigen) binding protein b
chr19_-_32641725 0.03 ENSDART00000165006
ENSDART00000188185
hpca
hippocalcin
chr21_+_20549395 0.03 ENSDART00000181633
efna5a
ephrin-A5a
chr9_+_7358749 0.02 ENSDART00000081660
ihha
Indian hedgehog homolog a
chr14_-_32503363 0.02 ENSDART00000034883
mcf2a
MCF.2 cell line derived transforming sequence a
chr25_-_29072162 0.02 ENSDART00000169269
arid3b
AT rich interactive domain 3B (BRIGHT-like)
chr11_-_29563437 0.02 ENSDART00000163958
arhgef10la
Rho guanine nucleotide exchange factor (GEF) 10-like a
chr7_-_26462831 0.01 ENSDART00000113543
mblac1
metallo-beta-lactamase domain containing 1
chr9_-_22076368 0.01 ENSDART00000128486
crygm2a
crystallin, gamma M2a
chr15_+_26603395 0.00 ENSDART00000188667
slc47a3
solute carrier family 47 (multidrug and toxin extrusion), member 3
chr5_+_44944778 0.00 ENSDART00000130428
ENSDART00000044361
ENSDART00000128825
ENSDART00000124637
ENSDART00000126066
ENSDART00000177635
dmrt1
doublesex and mab-3 related transcription factor 1
chr4_+_62598975 0.00 ENSDART00000163548
si:ch211-79g12.2
si:ch211-79g12.2
chr13_+_33655404 0.00 ENSDART00000023379
mgme1
mitochondrial genome maintenance exonuclease 1
chr7_-_33960170 0.00 ENSDART00000180766
skor1a
SKI family transcriptional corepressor 1a

Network of associatons between targets according to the STRING database.

First level regulatory network of rbpjb

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.1 GO:0072149 glomerular visceral epithelial cell fate commitment(GO:0072149) glomerular epithelial cell fate commitment(GO:0072314)
0.3 0.9 GO:0042822 pyridoxal phosphate metabolic process(GO:0042822) pyridoxal phosphate biosynthetic process(GO:0042823)
0.3 0.8 GO:0021531 spinal cord radial glial cell differentiation(GO:0021531)
0.2 1.8 GO:0043697 dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.2 0.6 GO:1903373 regulation of endoplasmic reticulum tubular network organization(GO:1903371) positive regulation of endoplasmic reticulum tubular network organization(GO:1903373)
0.2 0.5 GO:0021563 glossopharyngeal nerve development(GO:0021563)
0.1 0.6 GO:0006526 arginine biosynthetic process(GO:0006526)
0.1 1.4 GO:0001973 adenosine receptor signaling pathway(GO:0001973) purinergic receptor signaling pathway(GO:0035587) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.1 0.3 GO:0060063 Spemann organizer formation at the embryonic shield(GO:0060063)
0.1 0.5 GO:0021877 forebrain neuron fate commitment(GO:0021877)
0.1 0.5 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
0.1 0.3 GO:0060829 negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060829)
0.1 0.3 GO:0019464 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.1 0.6 GO:0060036 notochord cell vacuolation(GO:0060036)
0.1 0.3 GO:0051145 smooth muscle cell differentiation(GO:0051145)
0.1 0.4 GO:0006621 protein retention in ER lumen(GO:0006621)
0.1 0.2 GO:0070417 cellular response to cold(GO:0070417)
0.0 0.7 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782) protoporphyrinogen IX metabolic process(GO:0046501)
0.0 0.5 GO:0002084 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.0 0.3 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.0 0.6 GO:0006265 DNA topological change(GO:0006265)
0.0 0.5 GO:1901222 regulation of NIK/NF-kappaB signaling(GO:1901222)
0.0 0.5 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.0 0.3 GO:0008105 asymmetric protein localization(GO:0008105) apical protein localization(GO:0045176)
0.0 0.4 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 0.2 GO:2001239 histone dephosphorylation(GO:0016576) negative regulation of signal transduction in absence of ligand(GO:1901099) regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001239) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.0 0.2 GO:0016137 glycoside metabolic process(GO:0016137) glycoside catabolic process(GO:0016139)
0.0 0.1 GO:0007624 ultradian rhythm(GO:0007624)
0.0 0.2 GO:0071623 negative regulation of leukocyte chemotaxis(GO:0002689) negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of neutrophil chemotaxis(GO:0090024) negative regulation of neutrophil migration(GO:1902623)
0.0 0.3 GO:0070989 oxidative demethylation(GO:0070989)
0.0 0.2 GO:1902299 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.0 0.5 GO:1902622 regulation of neutrophil migration(GO:1902622)
0.0 0.8 GO:0043588 skin development(GO:0043588)
0.0 1.1 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 0.2 GO:0031274 pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.3 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.0 0.5 GO:0014866 skeletal myofibril assembly(GO:0014866)
0.0 0.2 GO:0050728 negative regulation of inflammatory response(GO:0050728)
0.0 0.3 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.0 0.3 GO:0010765 positive regulation of sodium ion transport(GO:0010765) positive regulation of sodium ion transmembrane transport(GO:1902307) regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288) positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.0 0.1 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.0 1.3 GO:0007030 Golgi organization(GO:0007030)
0.0 0.8 GO:0007062 sister chromatid cohesion(GO:0007062)
0.0 0.2 GO:0051764 actin crosslink formation(GO:0051764)
0.0 1.3 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 0.6 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.2 GO:0072698 protein localization to microtubule cytoskeleton(GO:0072698)
0.0 0.8 GO:0051607 defense response to virus(GO:0051607)
0.0 0.7 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 0.4 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.2 GO:0035435 phosphate ion transmembrane transport(GO:0035435)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0098826 endoplasmic reticulum tubular network membrane(GO:0098826)
0.1 0.6 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.1 0.5 GO:0005899 insulin receptor complex(GO:0005899)
0.1 0.7 GO:0035060 brahma complex(GO:0035060)
0.1 1.8 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.1 0.8 GO:0014704 intercalated disc(GO:0014704)
0.0 0.3 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.3 GO:0070938 contractile ring(GO:0070938)
0.0 0.8 GO:0008278 cohesin complex(GO:0008278)
0.0 0.2 GO:0031261 DNA replication preinitiation complex(GO:0031261)
0.0 0.1 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 0.2 GO:0043194 axon initial segment(GO:0043194)
0.0 1.1 GO:0016592 mediator complex(GO:0016592)
0.0 0.4 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 1.2 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.6 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.3 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 0.3 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.1 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.4 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.4 GO:0032156 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.1 GO:0005922 connexon complex(GO:0005922)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0016743 carboxyl- or carbamoyltransferase activity(GO:0016743)
0.1 0.6 GO:0016842 amidine-lyase activity(GO:0016842)
0.1 1.1 GO:0034452 dynactin binding(GO:0034452)
0.1 0.5 GO:0043560 insulin-activated receptor activity(GO:0005009) insulin receptor substrate binding(GO:0043560)
0.1 0.8 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.1 0.4 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 0.3 GO:0030626 U12 snRNA binding(GO:0030626)
0.1 0.7 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.1 0.7 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 1.1 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.7 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.6 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.2 GO:0030504 inorganic diphosphate transmembrane transporter activity(GO:0030504)
0.0 1.0 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 1.3 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.2 GO:0032052 bile acid binding(GO:0032052)
0.0 0.3 GO:0045309 protein phosphorylated amino acid binding(GO:0045309) phosphoprotein binding(GO:0051219)
0.0 0.8 GO:0005112 Notch binding(GO:0005112)
0.0 0.6 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.1 GO:0033842 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity(GO:0033842)
0.0 0.1 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.4 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.2 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.0 0.5 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.2 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.4 GO:0016251 obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.0 0.3 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.3 GO:0019869 chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.0 0.1 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 2.4 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.1 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.4 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 1.6 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879)
0.0 0.4 GO:0019003 GDP binding(GO:0019003)
0.0 0.5 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.7 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.6 PID AURORA B PATHWAY Aurora B signaling
0.0 0.2 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.8 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 0.3 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 1.5 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.8 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.5 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.5 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.5 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.3 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.2 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.2 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 0.7 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.7 REACTOME G1 PHASE Genes involved in G1 Phase