Project

PRJNA438478: RNAseq of wild type zebrafish germline

Navigation
Downloads

Results for si:dkey-149i17.7_zic1

Z-value: 0.82

Motif logo

logo of logo of

Transcription factors associated with si:dkey-149i17.7_zic1

Gene Symbol Gene ID Gene Info
si_dkey-149i17.7
ENSDARG00000094684 si_dkey-149i17.7
zic1
ENSDARG00000015567 zic family member 1 (odd-paired homolog, Drosophila)

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
si:dkey-149i17.7dr11_v1_chr2_+_24885987_24885987-0.194.5e-01Click!
zic1dr11_v1_chr24_-_4973765_49737650.068.2e-01Click!

Activity profile of si:dkey-149i17.7_zic1 motif

Sorted Z-values of si:dkey-149i17.7_zic1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr13_-_6250317 3.26 ENSDART00000180416
tuba4l
tubulin, alpha 4 like
chr8_+_14987006 3.13 ENSDART00000045038
fnbp1l
formin binding protein 1-like
chr2_+_41526904 2.88 ENSDART00000127520
acvr1l
activin A receptor, type 1 like
chr20_+_20731633 2.26 ENSDART00000191952
ENSDART00000165224
ppp1r13bb
protein phosphatase 1, regulatory subunit 13Bb
chr6_+_10338554 2.19 ENSDART00000186936
cobll1a
cordon-bleu WH2 repeat protein-like 1a
chr15_+_20239141 2.12 ENSDART00000101152
ENSDART00000152473
spint2
serine peptidase inhibitor, Kunitz type, 2
chr22_-_20924564 2.05 ENSDART00000100642
ENSDART00000032770
ell
elongation factor RNA polymerase II
chr15_+_45591669 2.03 ENSDART00000157459
atg16l1
ATG16 autophagy related 16-like 1 (S. cerevisiae)
chr16_+_31511739 1.94 ENSDART00000049420
ndrg1b
N-myc downstream regulated 1b
chr24_-_34680956 1.92 ENSDART00000171009
ctnna1
catenin (cadherin-associated protein), alpha 1
chr21_-_22357545 1.89 ENSDART00000134320
skp2
S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
chr11_+_14333441 1.88 ENSDART00000171969
ptbp1b
polypyrimidine tract binding protein 1b
chr17_+_24064014 1.87 ENSDART00000182782
ENSDART00000139063
ENSDART00000132755
b3gnt2b
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2b
chr22_-_14247276 1.76 ENSDART00000033332
si:ch211-246m6.5
si:ch211-246m6.5
chr18_+_3243292 1.75 ENSDART00000166580
pak1
p21 protein (Cdc42/Rac)-activated kinase 1
chr12_-_1034383 1.74 ENSDART00000152455
ENSDART00000152346
polr3e
polymerase (RNA) III (DNA directed) polypeptide E
chr14_-_34633960 1.72 ENSDART00000128869
ENSDART00000179977
afap1l1a
actin filament associated protein 1-like 1a
chr14_+_35428152 1.70 ENSDART00000172597
sytl4
synaptotagmin-like 4
chr23_+_40139765 1.67 ENSDART00000185376
gpsm2l
G protein signaling modulator 2, like
chr4_-_4535189 1.67 ENSDART00000057519
zgc:194209
zgc:194209
chr24_+_25822999 1.63 ENSDART00000109809
sh3kbp1
SH3-domain kinase binding protein 1
chr6_+_29923593 1.60 ENSDART00000169687
dlg1
discs, large homolog 1 (Drosophila)
chr18_+_3169579 1.60 ENSDART00000164724
ENSDART00000186340
ENSDART00000181247
ENSDART00000168056
pak1
p21 protein (Cdc42/Rac)-activated kinase 1
chr10_+_37182626 1.56 ENSDART00000137636
ksr1a
kinase suppressor of ras 1a
chr19_-_10915898 1.54 ENSDART00000163179
pip5k1aa
phosphatidylinositol-4-phosphate 5-kinase, type I, alpha, a
chr3_+_54047342 1.50 ENSDART00000178486
olfm2a
olfactomedin 2a
chr18_+_39487486 1.48 ENSDART00000126978
acadl
acyl-CoA dehydrogenase long chain
chr11_-_44999858 1.48 ENSDART00000167759
ENSDART00000126845
ldb1b
LIM-domain binding 1b
chr12_-_35393211 1.38 ENSDART00000137139
camk2g1
calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma 1
chr5_-_32332560 1.31 ENSDART00000083862
dab2
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr14_+_30285613 1.28 ENSDART00000173090
mtus1a
microtubule associated tumor suppressor 1a
chr9_+_33340311 1.26 ENSDART00000140064
ddx3a
DEAD (Asp-Glu-Ala-Asp) box helicase 3a
chr7_-_59514547 1.25 ENSDART00000168457
slx1b
SLX1 homolog B, structure-specific endonuclease subunit
chr7_+_39418869 1.25 ENSDART00000169195
CT030188.1

chr24_+_14801844 1.24 ENSDART00000141620
pi15a
peptidase inhibitor 15a
chr4_-_2162688 1.23 ENSDART00000148900
kcnc2
potassium voltage-gated channel, Shaw-related subfamily, member 2
chr11_-_669558 1.23 ENSDART00000173450
pparg
peroxisome proliferator-activated receptor gamma
chr21_-_42831033 1.21 ENSDART00000160998
stk10
serine/threonine kinase 10
chr19_-_1002959 1.20 ENSDART00000168138
ehmt2
euchromatic histone-lysine N-methyltransferase 2
chr23_-_32334208 1.19 ENSDART00000053472
rnf41
ring finger protein 41
chr6_+_3373665 1.19 ENSDART00000134133
st3gal3a
ST3 beta-galactoside alpha-2,3-sialyltransferase 3a
chr25_+_3759553 1.16 ENSDART00000180601
ENSDART00000055845
ENSDART00000157050
ENSDART00000153905
thoc5
THO complex 5
chr12_-_33789006 1.13 ENSDART00000034550
llgl2
lethal giant larvae homolog 2 (Drosophila)
chr9_-_28255029 1.13 ENSDART00000160387
ccnyl1
cyclin Y-like 1
chr2_+_44977889 1.12 ENSDART00000144024
alg3
asparagine-linked glycosylation 3 (alpha-1,3-mannosyltransferase)
chr11_-_669270 1.11 ENSDART00000172834
pparg
peroxisome proliferator-activated receptor gamma
chr18_+_907266 1.09 ENSDART00000171729
pkma
pyruvate kinase M1/2a
chr16_+_50755133 1.07 ENSDART00000029283
IGLON5
zgc:110372
chr17_-_25861787 1.07 ENSDART00000182503
BX000364.5

chr3_-_2613990 1.06 ENSDART00000137102
si:dkey-217f16.6
si:dkey-217f16.6
chr2_-_47957673 1.06 ENSDART00000056305
fzd8b
frizzled class receptor 8b
chr5_-_20921677 1.06 ENSDART00000158030
si:ch211-225b11.4
si:ch211-225b11.4
chr12_-_33789218 1.04 ENSDART00000193258
llgl2
lethal giant larvae homolog 2 (Drosophila)
chr16_-_25680666 1.04 ENSDART00000132693
ENSDART00000140539
ENSDART00000015302
tomm40
translocase of outer mitochondrial membrane 40 homolog (yeast)
chr18_+_34181655 1.04 ENSDART00000130831
ENSDART00000109535
gmps
guanine monophosphate synthase
chr19_-_29294457 1.03 ENSDART00000130815
ENSDART00000103437
e2f3
E2F transcription factor 3
chr11_+_24034345 1.01 ENSDART00000128309
zc3h11a
zinc finger CCCH-type containing 11A
chr12_-_13729263 0.98 ENSDART00000078021
foxh1
forkhead box H1
chr17_+_13664442 0.98 ENSDART00000171689
lrfn5a
leucine rich repeat and fibronectin type III domain containing 5a
chr7_-_18881358 0.98 ENSDART00000021502
mllt3
MLLT3, super elongation complex subunit
chr24_-_26854032 0.97 ENSDART00000087991
fndc3bb
fibronectin type III domain containing 3Bb
chr21_+_76739 0.96 ENSDART00000174654
ARSB
arylsulfatase B
chr16_+_50741154 0.96 ENSDART00000101627
IGLON5
zgc:110372
chr6_-_33707278 0.94 ENSDART00000188103
mast2
microtubule associated serine/threonine kinase 2
chr6_+_19933763 0.94 ENSDART00000166192
pik3r5
phosphoinositide-3-kinase, regulatory subunit 5
chr16_+_25296389 0.94 ENSDART00000114528
tbc1d31
TBC1 domain family, member 31
chr6_-_3978919 0.92 ENSDART00000167753
slc25a12
solute carrier family 25 (aspartate/glutamate carrier), member 12
chr10_-_2526526 0.92 ENSDART00000191726
ENSDART00000192767
CU856539.1

chr17_-_52941606 0.91 ENSDART00000155310
zgc:154061
zgc:154061
chr5_-_66823750 0.90 ENSDART00000041441
ENSDART00000112488
stip1
stress-induced phosphoprotein 1
chr17_+_24446353 0.90 ENSDART00000140467
ugp2b
UDP-glucose pyrophosphorylase 2b
chr21_-_4793686 0.90 ENSDART00000158232
notch1a
notch 1a
chr23_-_24226533 0.87 ENSDART00000109134
plekhm2
pleckstrin homology domain containing, family M (with RUN domain) member 2
chr18_+_35229115 0.83 ENSDART00000129624
ENSDART00000184596
tbrg1
transforming growth factor beta regulator 1
chr17_+_24446705 0.83 ENSDART00000163221
ugp2b
UDP-glucose pyrophosphorylase 2b
chr24_-_41267184 0.83 ENSDART00000063504
xylb
xylulokinase homolog (H. influenzae)
chr17_+_24446533 0.82 ENSDART00000131417
ugp2b
UDP-glucose pyrophosphorylase 2b
chr2_-_15041846 0.81 ENSDART00000139050
si:dkey-10f21.4
si:dkey-10f21.4
chr8_+_47219107 0.81 ENSDART00000146018
ENSDART00000075068
mthfr
methylenetetrahydrofolate reductase (NAD(P)H)
chr18_-_22094102 0.81 ENSDART00000100904
pard6a
par-6 family cell polarity regulator alpha
chr9_+_29430432 0.78 ENSDART00000125632
uggt2
UDP-glucose glycoprotein glucosyltransferase 2
chr18_+_3634652 0.76 ENSDART00000159913
lrch3
leucine-rich repeats and calponin homology (CH) domain containing 3
chr20_-_18794789 0.73 ENSDART00000003834
ccm2
cerebral cavernous malformation 2
chr24_-_17400143 0.73 ENSDART00000134947
cul1b
cullin 1b
chr4_-_11024767 0.72 ENSDART00000067261
ENSDART00000167631
tmtc2a
transmembrane and tetratricopeptide repeat containing 2a
chr9_-_21238159 0.71 ENSDART00000146764
ENSDART00000102143
cox17
COX17 cytochrome c oxidase copper chaperone
chr13_+_9559461 0.71 ENSDART00000047740
wdr32
WD repeat domain 32
chr2_-_37134169 0.71 ENSDART00000146123
ENSDART00000146533
ENSDART00000040427
elavl1a
ELAV like RNA binding protein 1a
chr11_-_10850936 0.70 ENSDART00000091901
psmd14
proteasome 26S subunit, non-ATPase 14
chr1_+_494297 0.69 ENSDART00000108579
ENSDART00000146732
blzf1
basic leucine zipper nuclear factor 1
chr8_+_30117297 0.69 ENSDART00000077554
fancc
Fanconi anemia, complementation group C
chr2_+_11031360 0.68 ENSDART00000180020
ENSDART00000145093
acot11a
acyl-CoA thioesterase 11a
chr24_-_17400472 0.67 ENSDART00000024691
cul1b
cullin 1b
chr23_-_40194732 0.67 ENSDART00000164931
tgm1l2
transglutaminase 1 like 2
chr11_-_36230146 0.67 ENSDART00000135888
ENSDART00000189782
rrp9
ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast)
chr5_+_37744625 0.67 ENSDART00000014031
dpf2
D4, zinc and double PHD fingers family 2
chr23_+_28718863 0.66 ENSDART00000078156
srm
spermidine synthase
chr11_-_28747 0.66 ENSDART00000172956
sp1
sp1 transcription factor
chr9_+_8364553 0.64 ENSDART00000190713
si:dkey-90l23.2
si:dkey-90l23.2
chr11_+_41838801 0.64 ENSDART00000014871
akr7a3
aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase)
chr13_+_40334727 0.64 ENSDART00000074950
slc25a28
solute carrier family 25 (mitochondrial iron transporter), member 28
chr21_+_33311622 0.63 ENSDART00000163808
si:ch211-151g22.1
si:ch211-151g22.1
chr3_-_31254979 0.63 ENSDART00000130280
apnl
actinoporin-like protein
chr21_+_26991198 0.62 ENSDART00000065397
fkbp2
FK506 binding protein 2
chr18_+_1615 0.62 ENSDART00000082450
homer2
homer scaffolding protein 2
chr23_+_1349277 0.59 ENSDART00000173133
ENSDART00000179877
utrn
utrophin
chr22_-_37738203 0.58 ENSDART00000143190
acap2
ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
chr5_-_72178739 0.55 ENSDART00000050971
rab14l
RAB14, member RAS oncogene family, like
chr15_+_29728377 0.52 ENSDART00000099958
zgc:153372
zgc:153372
chr2_+_25378457 0.51 ENSDART00000089108
fndc3ba
fibronectin type III domain containing 3Ba
chr21_-_40557281 0.51 ENSDART00000172327
taok1b
TAO kinase 1b
chr23_-_4704938 0.50 ENSDART00000067293
cnbpa
CCHC-type zinc finger, nucleic acid binding protein a
chr14_+_23709543 0.50 ENSDART00000136909
gnpda1
glucosamine-6-phosphate deaminase 1
chr20_-_18731268 0.50 ENSDART00000183893
enpp5
ectonucleotide pyrophosphatase/phosphodiesterase 5
chr8_+_26874924 0.50 ENSDART00000141794
rimkla
ribosomal modification protein rimK-like family member A
chr13_+_31172833 0.50 ENSDART00000176378
CR931802.3

chr7_-_7692723 0.49 ENSDART00000183352
aadat
aminoadipate aminotransferase
chr8_-_20838342 0.49 ENSDART00000141345
si:ch211-133l5.7
si:ch211-133l5.7
chr16_-_40426837 0.49 ENSDART00000193690
plekhf2
pleckstrin homology domain containing, family F (with FYVE domain) member 2
chr8_+_22277198 0.48 ENSDART00000005989
dffb
DNA fragmentation factor, beta polypeptide (caspase-activated DNase)
chr8_-_25600888 0.48 ENSDART00000193860
stk38a
serine/threonine kinase 38a
chr21_+_3901775 0.48 ENSDART00000053609
dolpp1
dolichyldiphosphatase 1
chr13_-_41482064 0.47 ENSDART00000188322
ENSDART00000164732
pcdh15a
protocadherin-related 15a
chr21_-_13230925 0.47 ENSDART00000023834
setb
SET nuclear proto-oncogene b
chr17_+_33296852 0.47 ENSDART00000154580
dnajc27
DnaJ (Hsp40) homolog, subfamily C, member 27
chr7_-_23848012 0.47 ENSDART00000146104
ENSDART00000175108
si:ch211-200p22.4
si:ch211-200p22.4
chr17_-_15667198 0.46 ENSDART00000142972
ENSDART00000132571
ENSDART00000189936
manea
mannosidase, endo-alpha
chr14_+_35405518 0.45 ENSDART00000171565
zbtb3
zinc finger and BTB domain containing 3
chr14_-_47882706 0.45 ENSDART00000188772
rapgef2
Rap guanine nucleotide exchange factor (GEF) 2
chr7_-_7692992 0.45 ENSDART00000192619
aadat
aminoadipate aminotransferase
chr4_+_6869847 0.45 ENSDART00000036646
dock4b
dedicator of cytokinesis 4b
chr19_-_48010490 0.44 ENSDART00000159938
FBXL19
zgc:158376
chr19_-_17996162 0.44 ENSDART00000150928
ENSDART00000104491
ints8
integrator complex subunit 8
chr3_-_21061931 0.43 ENSDART00000036741
fam57ba
family with sequence similarity 57, member Ba
chr3_+_46479913 0.43 ENSDART00000149755
tyk2
tyrosine kinase 2
chr13_-_25719628 0.43 ENSDART00000135383
si:dkey-192p21.6
si:dkey-192p21.6
chr6_+_16493755 0.42 ENSDART00000126318
si:ch73-193c12.2
si:ch73-193c12.2
chr9_+_34380299 0.42 ENSDART00000131705
lamp1
lysosomal-associated membrane protein 1
chr15_+_47083163 0.42 ENSDART00000097465
cep57
centrosomal protein 57
chr5_-_5326010 0.41 ENSDART00000161946
pbx3a
pre-B-cell leukemia homeobox 3a
chr25_+_37435720 0.41 ENSDART00000164390
chmp1a
charged multivesicular body protein 1A
chr5_-_45651548 0.41 ENSDART00000097645
NPFFR2
neuropeptide FF receptor 2a
chr19_-_17996336 0.40 ENSDART00000186143
ENSDART00000080751
ints8
integrator complex subunit 8
chr8_+_54055390 0.40 ENSDART00000102696
magi1a
membrane associated guanylate kinase, WW and PDZ domain containing 1a
chr24_+_36018164 0.39 ENSDART00000182815
ENSDART00000126941
gnal2
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type 2
chr24_+_39227519 0.39 ENSDART00000184611
ENSDART00000193494
ENSDART00000190728
ENSDART00000168705
MPRIP
si:ch73-103b11.2
chr21_-_13231101 0.38 ENSDART00000190943
setb
SET nuclear proto-oncogene b
chr5_-_32074534 0.38 ENSDART00000112342
ENSDART00000135855
arpc5lb
actin related protein 2/3 complex, subunit 5-like, b
chr15_-_25613114 0.38 ENSDART00000182431
ENSDART00000187405
taok1a
TAO kinase 1a
chr14_-_4043818 0.38 ENSDART00000179870
snx25
sorting nexin 25
chr8_-_4574328 0.37 ENSDART00000090731
dhx37
DEAH (Asp-Glu-Ala-His) box polypeptide 37
chr14_-_30876708 0.37 ENSDART00000147597
ubl3b
ubiquitin-like 3b
chr21_+_3093419 0.37 ENSDART00000162520
SHC3
SHC adaptor protein 3
chr17_-_27048537 0.36 ENSDART00000050018
ENSDART00000193861
cnksr1
connector enhancer of kinase suppressor of Ras 1
chr10_+_589501 0.36 ENSDART00000188415
LO018557.1

chr23_+_27789795 0.36 ENSDART00000141458
kmt2d
lysine (K)-specific methyltransferase 2D
chr23_-_25126003 0.36 ENSDART00000034953
idh3g
isocitrate dehydrogenase 3 (NAD+) gamma
chr7_-_5396154 0.36 ENSDART00000172980
arhgef11
Rho guanine nucleotide exchange factor (GEF) 11
chr13_-_44843819 0.36 ENSDART00000140442
si:dkeyp-2e4.3
si:dkeyp-2e4.3
chr13_-_24396199 0.35 ENSDART00000181093
tbp
TATA box binding protein
chr25_-_27729046 0.35 ENSDART00000131437
zgc:153935
zgc:153935
chr2_+_51028269 0.34 ENSDART00000161254
eef1da
eukaryotic translation elongation factor 1 delta a (guanine nucleotide exchange protein)
chr16_+_33142734 0.34 ENSDART00000138244
rhbdl2
rhomboid, veinlet-like 2 (Drosophila)
chr16_+_2905150 0.34 ENSDART00000109980
lars2
leucyl-tRNA synthetase 2, mitochondrial
chr5_-_21044693 0.32 ENSDART00000140298
si:dkey-13n15.2
si:dkey-13n15.2
chr3_+_52078798 0.32 ENSDART00000156882
si:dkey-88e12.3
si:dkey-88e12.3
chr3_-_40162843 0.32 ENSDART00000129664
ENSDART00000025285
drg2
developmentally regulated GTP binding protein 2
chr25_-_893464 0.31 ENSDART00000159321
znf609a
zinc finger protein 609a
chr13_+_10799380 0.31 ENSDART00000126427
lrpprc
leucine-rich pentatricopeptide repeat containing
chr25_-_16782394 0.30 ENSDART00000019413
ndufa9a
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9a
chr5_-_37044262 0.30 ENSDART00000166670
si:dkeyp-110c7.8
si:dkeyp-110c7.8
chr19_-_27391179 0.30 ENSDART00000181108
mgat1b
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase b
chr20_-_54522660 0.30 ENSDART00000059872
ppp1r35
protein phosphatase 1, regulatory subunit 35
chr22_+_35275206 0.30 ENSDART00000112234
rubcn
RUN domain and cysteine-rich domain containing, Beclin 1-interacting protein
chr7_-_40959867 0.29 ENSDART00000174009
rbm33a
RNA binding motif protein 33a
chr3_+_27722355 0.29 ENSDART00000132761
arhgdig
Rho GDP dissociation inhibitor (GDI) gamma
chr1_+_45085194 0.29 ENSDART00000193863
si:ch211-151p13.8
si:ch211-151p13.8
chr24_+_31379318 0.28 ENSDART00000183707
cpne3
copine III
chr22_+_30038459 0.28 ENSDART00000177014
AL845330.1

chr12_+_4225199 0.28 ENSDART00000042277
mapk7
mitogen-activated protein kinase 7
chr17_-_3303805 0.28 ENSDART00000169136
CABZ01007222.1

chr19_+_1999838 0.28 ENSDART00000166669
btd
biotinidase
chr19_-_32641725 0.26 ENSDART00000165006
ENSDART00000188185
hpca
hippocalcin
chr17_+_23926796 0.26 ENSDART00000021177
pex13
peroxisomal biogenesis factor 13
chr7_+_67429185 0.26 ENSDART00000162553
ENSDART00000178646
kars
lysyl-tRNA synthetase
chr8_-_11770092 0.26 ENSDART00000091684
anapc7
anaphase promoting complex subunit 7
chr13_-_33198150 0.25 ENSDART00000137576
trip11
thyroid hormone receptor interactor 11
chr1_-_59313465 0.25 ENSDART00000158067
ENSDART00000159419
txndc11
thioredoxin domain containing 11
chr18_-_45736 0.25 ENSDART00000148373
ENSDART00000148950
gatm
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr22_+_2648931 0.25 ENSDART00000106357
zgc:110821
zgc:110821
chr10_+_35329751 0.24 ENSDART00000148043
si:dkey-259j3.5
si:dkey-259j3.5
chr1_-_20068155 0.24 ENSDART00000102993
mettl14
methyltransferase like 14
chr11_-_28224 0.24 ENSDART00000124104
sp1
sp1 transcription factor
chr10_-_18492617 0.24 ENSDART00000179936
ENSDART00000193799
ENSDART00000193198
si:dkey-28o19.1
si:dkey-28o19.1
chr8_-_14126646 0.24 ENSDART00000027225
bgna
biglycan a
chr8_+_31777633 0.23 ENSDART00000142519
oxct1a
3-oxoacid CoA transferase 1a
chr2_-_39558643 0.23 ENSDART00000139860
ENSDART00000145231
ENSDART00000141721
cbln7
cerebellin 7
chr16_+_26706519 0.22 ENSDART00000142706
virma
vir like m6A methyltransferase associated
chr10_-_1523253 0.22 ENSDART00000179510
ENSDART00000176548
ENSDART00000180368
ENSDART00000185270
WDR70
WD repeat domain 70
chr25_+_16080181 0.21 ENSDART00000061753
far1
fatty acyl CoA reductase 1

Network of associatons between targets according to the STRING database.

First level regulatory network of si:dkey-149i17.7_zic1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.9 GO:0035124 embryonic caudal fin morphogenesis(GO:0035124)
0.6 3.3 GO:0003232 bulbus arteriosus development(GO:0003232)
0.5 2.5 GO:0006011 UDP-glucose metabolic process(GO:0006011)
0.4 2.2 GO:0010719 photoreceptor cell morphogenesis(GO:0008594) negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.4 2.0 GO:0039694 viral genome replication(GO:0019079) negative stranded viral RNA replication(GO:0039689) viral RNA genome replication(GO:0039694) RNA replication(GO:0039703) multi-organism biosynthetic process(GO:0044034)
0.3 2.1 GO:0042795 snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.3 1.0 GO:0060063 Spemann organizer formation at the embryonic shield(GO:0060063)
0.3 0.9 GO:0021531 spinal cord radial glial cell differentiation(GO:0021531)
0.3 1.5 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.3 1.9 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.3 0.8 GO:0005997 xylulose metabolic process(GO:0005997)
0.2 1.1 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.2 1.2 GO:0051570 regulation of histone H3-K9 methylation(GO:0051570)
0.2 0.9 GO:0032655 interleukin-12 production(GO:0032615) regulation of interleukin-12 production(GO:0032655)
0.2 0.5 GO:0018872 arsonoacetate metabolic process(GO:0018872)
0.2 0.5 GO:0006043 glucosamine metabolic process(GO:0006041) glucosamine catabolic process(GO:0006043)
0.2 2.3 GO:0070328 acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328)
0.2 1.3 GO:2000725 regulation of cardiocyte differentiation(GO:1905207) regulation of cardiac muscle cell differentiation(GO:2000725)
0.1 0.4 GO:0006601 creatine metabolic process(GO:0006600) creatine biosynthetic process(GO:0006601)
0.1 0.8 GO:0044364 killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364) disruption of cells of other organism involved in symbiotic interaction(GO:0051818) killing of cells in other organism involved in symbiotic interaction(GO:0051883)
0.1 0.5 GO:0090387 phagosome maturation involved in apoptotic cell clearance(GO:0090386) phagolysosome assembly involved in apoptotic cell clearance(GO:0090387)
0.1 1.9 GO:0030311 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.1 0.5 GO:2000767 positive regulation of cytoplasmic translation(GO:2000767)
0.1 0.2 GO:0060019 radial glial cell differentiation(GO:0060019)
0.1 1.0 GO:0046037 GMP biosynthetic process(GO:0006177) GMP metabolic process(GO:0046037)
0.1 0.3 GO:0042245 RNA repair(GO:0042245)
0.1 1.6 GO:0061154 endothelial tube morphogenesis(GO:0061154) blood vessel lumenization(GO:0072554)
0.1 0.3 GO:1901004 ubiquinone-6 metabolic process(GO:1901004) ubiquinone-6 biosynthetic process(GO:1901006)
0.1 0.3 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553) negative regulation of lipid kinase activity(GO:0090219)
0.1 0.9 GO:0015813 acidic amino acid transport(GO:0015800) aspartate transport(GO:0015810) L-glutamate transport(GO:0015813) malate-aspartate shuttle(GO:0043490)
0.1 1.1 GO:1903729 regulation of plasma membrane organization(GO:1903729)
0.1 0.4 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.1 0.6 GO:0021553 olfactory nerve development(GO:0021553) olfactory nerve morphogenesis(GO:0021627) olfactory nerve formation(GO:0021628)
0.1 0.7 GO:0008216 spermidine metabolic process(GO:0008216)
0.1 1.6 GO:1902807 negative regulation of cell cycle G1/S phase transition(GO:1902807) negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.1 1.0 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.1 0.2 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.1 0.5 GO:0006309 apoptotic DNA fragmentation(GO:0006309) cellular component disassembly involved in execution phase of apoptosis(GO:0006921) apoptotic nuclear changes(GO:0030262)
0.1 1.1 GO:0035278 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.1 1.0 GO:0009086 methionine biosynthetic process(GO:0009086)
0.1 1.2 GO:2000401 regulation of lymphocyte migration(GO:2000401)
0.1 1.0 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.1 0.2 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 0.7 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.1 1.2 GO:0071427 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.1 1.4 GO:0038061 NIK/NF-kappaB signaling(GO:0038061)
0.0 0.8 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 0.2 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.4 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.1 GO:1900182 positive regulation of protein localization to nucleus(GO:1900182) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
0.0 0.4 GO:0003422 growth plate cartilage morphogenesis(GO:0003422) chondrocyte intercalation involved in growth plate cartilage morphogenesis(GO:0003428)
0.0 0.7 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.1 GO:0061033 lung growth(GO:0060437) secretion by lung epithelial cell involved in lung growth(GO:0061033)
0.0 1.9 GO:0000086 G2/M transition of mitotic cell cycle(GO:0000086)
0.0 0.2 GO:0051659 maintenance of mitochondrion location(GO:0051659)
0.0 0.8 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.7 GO:0018149 peptide cross-linking(GO:0018149)
0.0 1.1 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.5 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.0 0.1 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.0 0.7 GO:0097194 execution phase of apoptosis(GO:0097194)
0.0 1.1 GO:0072114 pronephros morphogenesis(GO:0072114)
0.0 0.1 GO:0060829 negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060829)
0.0 0.1 GO:1903726 negative regulation of phospholipid metabolic process(GO:1903726)
0.0 0.3 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.6 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.0 0.7 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 0.3 GO:1901970 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0 0.4 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.3 GO:0036065 fucosylation(GO:0036065)
0.0 0.7 GO:0001878 response to yeast(GO:0001878)
0.0 0.4 GO:0034453 microtubule anchoring(GO:0034453)
0.0 1.9 GO:0001894 tissue homeostasis(GO:0001894)
0.0 0.8 GO:0001841 neural tube formation(GO:0001841)
0.0 0.1 GO:0019805 quinolinate biosynthetic process(GO:0019805) quinolinate metabolic process(GO:0046874)
0.0 0.9 GO:0035567 non-canonical Wnt signaling pathway(GO:0035567)
0.0 1.5 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 1.1 GO:0006096 glycolytic process(GO:0006096)
0.0 0.3 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.0 0.3 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.2 GO:0019730 antimicrobial humoral response(GO:0019730)
0.0 0.1 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898) positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 0.3 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 0.1 GO:0022615 protein import into peroxisome matrix, docking(GO:0016560) protein to membrane docking(GO:0022615)
0.0 1.3 GO:0000724 double-strand break repair via homologous recombination(GO:0000724)
0.0 1.7 GO:0045786 negative regulation of cell cycle(GO:0045786)
0.0 3.1 GO:0006914 autophagy(GO:0006914)
0.0 0.3 GO:0043652 engulfment of apoptotic cell(GO:0043652)
0.0 0.7 GO:0055088 lipid homeostasis(GO:0055088)
0.0 0.7 GO:0001570 vasculogenesis(GO:0001570)
0.0 0.4 GO:0043149 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.9 GO:0070724 BMP receptor complex(GO:0070724)
0.3 0.8 GO:0044218 other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217) other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.3 2.2 GO:0000346 transcription export complex(GO:0000346)
0.2 1.3 GO:0033557 Slx1-Slx4 complex(GO:0033557)
0.1 1.7 GO:0002102 podosome(GO:0002102)
0.1 1.9 GO:0030057 desmosome(GO:0030057)
0.1 1.0 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.1 1.2 GO:0098827 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.1 1.7 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 1.2 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.1 0.9 GO:0097651 phosphatidylinositol 3-kinase complex, class IB(GO:0005944) phosphatidylinositol 3-kinase complex, class I(GO:0097651)
0.1 0.2 GO:1990415 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.1 0.7 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1 0.7 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1 0.2 GO:0045293 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.1 0.6 GO:0098835 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) extrinsic component of presynaptic membrane(GO:0098888) extrinsic component of presynaptic endocytic zone(GO:0098894)
0.1 0.2 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.1 2.0 GO:0000421 autophagosome membrane(GO:0000421)
0.1 1.6 GO:0031594 neuromuscular junction(GO:0031594)
0.0 2.2 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.3 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.8 GO:0032039 integrator complex(GO:0032039)
0.0 3.3 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.7 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 2.1 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.5 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 0.6 GO:0071565 nBAF complex(GO:0071565)
0.0 0.4 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.4 GO:0032420 stereocilium(GO:0032420)
0.0 0.4 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.7 GO:0032040 small-subunit processome(GO:0032040)
0.0 0.7 GO:0031970 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 0.1 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.3 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.3 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.2 GO:0044295 axonal growth cone(GO:0044295)
0.0 3.3 GO:0005938 cell cortex(GO:0005938)
0.0 0.8 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 1.1 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 1.6 GO:0005925 focal adhesion(GO:0005925)
0.0 0.2 GO:0030315 T-tubule(GO:0030315)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.5 GO:0003983 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.5 1.5 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.5 2.3 GO:0070644 vitamin D response element binding(GO:0070644)
0.4 1.5 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.3 1.1 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.3 1.3 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.2 2.9 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.2 1.5 GO:0030274 LIM domain binding(GO:0030274)
0.2 1.1 GO:0004743 pyruvate kinase activity(GO:0004743)
0.2 0.5 GO:0030792 arsenite methyltransferase activity(GO:0030791) methylarsonite methyltransferase activity(GO:0030792)
0.2 1.2 GO:0008118 N-acetyllactosaminide alpha-2,3-sialyltransferase activity(GO:0008118)
0.2 0.7 GO:0034511 U3 snoRNA binding(GO:0034511)
0.2 0.5 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.2 0.5 GO:0072590 N-acetyl-L-aspartate-L-glutamate ligase activity(GO:0072590) citrate-L-glutamate ligase activity(GO:0072591)
0.2 0.8 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.2 2.8 GO:0002039 p53 binding(GO:0002039)
0.2 1.7 GO:0016840 carbon-nitrogen lyase activity(GO:0016840)
0.1 0.7 GO:0016531 copper chaperone activity(GO:0016531)
0.1 0.9 GO:0016212 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.1 1.9 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.1 2.2 GO:0045159 myosin II binding(GO:0045159)
0.1 2.2 GO:0003785 actin monomer binding(GO:0003785)
0.1 0.7 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.1 0.2 GO:0001734 mRNA (N6-adenosine)-methyltransferase activity(GO:0001734)
0.1 0.9 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.1 0.3 GO:0043734 oxidative DNA demethylase activity(GO:0035516) DNA-N1-methyladenine dioxygenase activity(GO:0043734) RNA N6-methyladenosine dioxygenase activity(GO:1990931)
0.1 0.3 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.1 1.0 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.1 0.4 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.1 0.3 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 1.0 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.1 1.1 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.9 GO:0051879 Hsp90 protein binding(GO:0051879)
0.1 0.2 GO:0042806 fucose binding(GO:0042806)
0.1 1.5 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 3.3 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 0.9 GO:0005080 protein kinase C binding(GO:0005080)
0.1 0.7 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.6 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.7 GO:0070628 proteasome binding(GO:0070628)
0.0 0.3 GO:0000995 transcription factor activity, core RNA polymerase III binding(GO:0000995)
0.0 0.2 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.0 0.3 GO:0016426 tRNA (adenine) methyltransferase activity(GO:0016426)
0.0 2.0 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.2 GO:0008887 glycerate kinase activity(GO:0008887)
0.0 0.9 GO:0019894 kinesin binding(GO:0019894)
0.0 0.9 GO:0005112 Notch binding(GO:0005112)
0.0 0.3 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.0 0.7 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.2 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.0 1.4 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.8 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.0 0.5 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.0 1.7 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.9 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.4 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.3 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 0.4 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 1.2 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 1.9 GO:0019902 phosphatase binding(GO:0019902)
0.0 0.2 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.9 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 1.0 GO:0046332 SMAD binding(GO:0046332)
0.0 0.4 GO:0016769 transferase activity, transferring nitrogenous groups(GO:0016769)
0.0 0.2 GO:0051920 peroxiredoxin activity(GO:0051920)
0.0 1.1 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.4 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 3.9 GO:0042802 identical protein binding(GO:0042802)
0.0 0.1 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.1 GO:0004968 gonadotropin-releasing hormone receptor activity(GO:0004968)
0.0 0.5 GO:0045182 translation regulator activity(GO:0045182)
0.0 0.4 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.6 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.1 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.0 0.9 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.0 0.7 GO:0004536 deoxyribonuclease activity(GO:0004536)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.3 PID S1P S1P2 PATHWAY S1P2 pathway
0.1 2.3 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 1.9 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.1 0.4 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.1 1.2 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.1 2.8 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.1 1.6 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.7 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.9 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.8 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.6 PID ARF6 PATHWAY Arf6 signaling events
0.0 1.3 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.5 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.8 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.7 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.3 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.4 PID IL3 PATHWAY IL3-mediated signaling events
0.0 1.0 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.6 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.6 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 1.0 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.3 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.4 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.1 PID NETRIN PATHWAY Netrin-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.3 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.2 1.3 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.2 0.8 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 1.2 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1 1.6 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 1.7 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.1 1.5 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 1.0 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 0.5 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.1 2.1 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.1 1.0 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 1.9 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 1.0 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 2.9 REACTOME G1 PHASE Genes involved in G1 Phase
0.1 1.0 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 1.6 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.1 3.0 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.1 0.9 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.1 0.8 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.1 1.2 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.1 2.3 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 0.9 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.0 0.3 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0 0.4 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 1.6 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.8 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 1.2 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0 0.7 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.4 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.3 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.6 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.2 REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.0 0.9 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.0 0.8 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.3 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.1 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.1 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation