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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for si:dkey-18a10.3

Z-value: 0.53

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Transcription factors associated with si:dkey-18a10.3

Gene Symbol Gene ID Gene Info
si_dkey-18a10.3
ENSDARG00000090814 si_dkey-18a10.3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
si:dkey-18a10.3dr11_v1_chr10_-_33572441_335724410.735.7e-04Click!

Activity profile of si:dkey-18a10.3 motif

Sorted Z-values of si:dkey-18a10.3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr23_-_31372639 1.65 ENSDART00000179908
ENSDART00000135620
ENSDART00000053367
hmgn3
high mobility group nucleosomal binding domain 3
chr6_+_518979 1.50 ENSDART00000151012
CACNA1I (1 of many)
si:ch73-379f7.5
chr16_+_30575901 1.42 ENSDART00000077231
mc2r
melanocortin 2 receptor
chr9_+_44431174 1.29 ENSDART00000149726
ppp1r1c
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr16_+_34523515 1.16 ENSDART00000041007
stmn1b
stathmin 1b
chr10_-_36682509 1.16 ENSDART00000148093
ENSDART00000063365
dnajb13
DnaJ (Hsp40) homolog, subfamily B, member 13
chr15_+_36941490 1.10 ENSDART00000172664
kirrel3l
kirre like nephrin family adhesion molecule 3, like
chr3_-_41535647 1.09 ENSDART00000153723
ENSDART00000154198
si:ch211-222n22.1
si:ch211-222n22.1
chr6_+_49095646 1.04 ENSDART00000103385
slc25a55a
solute carrier family 25, member 55a
chr25_-_18470695 1.01 ENSDART00000034377
cpa5
carboxypeptidase A5
chr5_-_20879527 0.99 ENSDART00000134697
pik3ip1
phosphoinositide-3-kinase interacting protein 1
chr19_+_46259619 0.98 ENSDART00000158032
grinaa
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1a (glutamate binding)
chr5_-_23200880 0.97 ENSDART00000051531
iqcd
IQ motif containing D
chr9_-_56272465 0.93 ENSDART00000039235
lcp1
lymphocyte cytosolic protein 1 (L-plastin)
chr16_+_46666074 0.89 ENSDART00000074919
ENSDART00000142698
ubqln4
ubiquilin 4
chr21_-_25756119 0.86 ENSDART00000002341
cldnc
claudin c
chr12_+_45200744 0.84 ENSDART00000098932
wbp2
WW domain binding protein 2
chr20_-_44496245 0.82 ENSDART00000012229
fkbp1b
FK506 binding protein 1b
chr17_+_12159529 0.82 ENSDART00000046802
sccpdha
saccharopine dehydrogenase a
chr3_-_59981476 0.81 ENSDART00000035878
ENSDART00000124038
cdr2l
cerebellar degeneration-related protein 2-like
chr20_+_15552657 0.80 ENSDART00000063912
jun
Jun proto-oncogene, AP-1 transcription factor subunit
chr2_-_26563978 0.73 ENSDART00000150016
glis1a
GLIS family zinc finger 1a
chr1_-_59411901 0.72 ENSDART00000167015
si:ch211-188p14.4
si:ch211-188p14.4
chr20_-_53996193 0.72 ENSDART00000004756
hsp90aa1.1
heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 1
chr5_+_28313824 0.68 ENSDART00000135878
si:dkeyp-86b9.1
si:dkeyp-86b9.1
chr10_+_18952271 0.65 ENSDART00000146517
dpysl2b
dihydropyrimidinase-like 2b
chr22_+_22021936 0.62 ENSDART00000149586
gna15.1
guanine nucleotide binding protein (G protein), alpha 15 (Gq class), tandem duplicate 1
chr24_+_7495945 0.62 ENSDART00000133525
ENSDART00000182460
ENSDART00000162954
kmt2ca
lysine (K)-specific methyltransferase 2Ca
chr21_+_21012210 0.62 ENSDART00000190317
ndr1
nodal-related 1
chr7_-_51102479 0.61 ENSDART00000174023
col4a6
collagen, type IV, alpha 6
chr1_-_53714885 0.59 ENSDART00000026409
cct4
chaperonin containing TCP1, subunit 4 (delta)
chr8_-_1909840 0.59 ENSDART00000147408
si:dkey-178e17.3
si:dkey-178e17.3
chr16_+_41517188 0.59 ENSDART00000049976
si:dkey-11p23.7
si:dkey-11p23.7
chr13_-_45475289 0.57 ENSDART00000043345
rsrp1
arginine/serine-rich protein 1
chr1_-_14258409 0.57 ENSDART00000079359
pde5aa
phosphodiesterase 5A, cGMP-specific, a
chr11_-_36040549 0.57 ENSDART00000112684
setmar
SET domain and mariner transposase fusion gene
chr7_-_20103384 0.56 ENSDART00000052902
acap1
ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
chr23_-_35066816 0.56 ENSDART00000168731
ENSDART00000163731
BX294434.1

chr23_-_46217134 0.55 ENSDART00000189477
ENSDART00000168352
CABZ01102528.1

chr18_+_14477740 0.55 ENSDART00000146472
kcng4a
potassium voltage-gated channel, subfamily G, member 4a
chr7_+_38750871 0.54 ENSDART00000114238
ENSDART00000052325
ENSDART00000137001
f2
coagulation factor II (thrombin)
chr25_+_14165447 0.53 ENSDART00000145387
shank2
SH3 and multiple ankyrin repeat domains 2
chr19_-_35596207 0.53 ENSDART00000136811
col8a2
collagen, type VIII, alpha 2
chr1_+_54606354 0.51 ENSDART00000125227
si:ch211-202h22.10
si:ch211-202h22.10
chr25_+_19999623 0.50 ENSDART00000026401
zgc:194665
zgc:194665
chr12_+_49135755 0.49 ENSDART00000153460
si:zfos-911d5.4
si:zfos-911d5.4
chr12_+_48581588 0.48 ENSDART00000114996
CABZ01078415.1

chr3_+_6443992 0.47 ENSDART00000169325
ENSDART00000162255
nup85
nucleoporin 85
chr3_+_26267725 0.45 ENSDART00000131288
adap2
ArfGAP with dual PH domains 2
chr4_-_17055782 0.45 ENSDART00000134595
sox5
SRY (sex determining region Y)-box 5
chr13_-_23007813 0.45 ENSDART00000057638
hk1
hexokinase 1
chr14_-_1990290 0.44 ENSDART00000183382
pcdh2g5
protocadherin 2 gamma 5
chr13_-_31452516 0.44 ENSDART00000193268
rtn1a
reticulon 1a
chr1_-_8691969 0.43 ENSDART00000152153
abcg2b
ATP-binding cassette, sub-family G (WHITE), member 2b
chr1_+_2101541 0.43 ENSDART00000128187
ENSDART00000167050
ENSDART00000182153
ENSDART00000122626
ENSDART00000164488
mbnl2
muscleblind-like splicing regulator 2
chr7_-_55539738 0.42 ENSDART00000168721
ENSDART00000013796
ENSDART00000148514
aprt
adenine phosphoribosyltransferase
chr24_+_21973929 0.41 ENSDART00000042495
sat1b
spermidine/spermine N1-acetyltransferase 1b
chr24_-_39858710 0.40 ENSDART00000134251
slc12a7b
solute carrier family 12 (potassium/chloride transporter), member 7b
chr21_-_5881344 0.39 ENSDART00000009241
rpl35
ribosomal protein L35
chr9_+_44430974 0.39 ENSDART00000056846
ppp1r1c
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr15_-_1484795 0.39 ENSDART00000129356
si:dkeyp-97b10.3
si:dkeyp-97b10.3
chr10_-_26274094 0.36 ENSDART00000108798
dchs1b
dachsous cadherin-related 1b
chr22_-_607812 0.35 ENSDART00000145983
cdkn1a
cyclin-dependent kinase inhibitor 1A
chr25_+_35942867 0.35 ENSDART00000066985
hsd17b2
hydroxysteroid (17-beta) dehydrogenase 2
chr4_+_35553514 0.34 ENSDART00000182938
CR847906.1

chr15_-_22147860 0.34 ENSDART00000149784
scn3b
sodium channel, voltage-gated, type III, beta
chr16_+_21330634 0.33 ENSDART00000191285
ENSDART00000183267
osbpl3b
oxysterol binding protein-like 3b
chr7_+_29954709 0.33 ENSDART00000173904
tpma
alpha-tropomyosin
chr22_-_14115292 0.33 ENSDART00000105717
ENSDART00000165670
aox5
aldehyde oxidase 5
chr1_-_26063188 0.33 ENSDART00000168640
pdcd4a
programmed cell death 4a
chr4_-_18850799 0.32 ENSDART00000151844
mcat
malonyl CoA:ACP acyltransferase (mitochondrial)
chr5_-_42060121 0.32 ENSDART00000148021
ENSDART00000147407
cenpv
centromere protein V
chr5_-_42059869 0.32 ENSDART00000193984
cenpv
centromere protein V
chr4_-_52165969 0.31 ENSDART00000171130
si:dkeyp-44b5.4
si:dkeyp-44b5.4
chr1_-_9195629 0.29 ENSDART00000143587
ENSDART00000192174
ern2
endoplasmic reticulum to nucleus signaling 2
chr1_+_46652615 0.29 ENSDART00000053221
arl11
ADP-ribosylation factor-like 11
chr13_+_24834199 0.29 ENSDART00000101274
zgc:153981
zgc:153981
chr18_-_45617146 0.28 ENSDART00000146543
wt1b
wilms tumor 1b
chr1_+_16466771 0.28 ENSDART00000162389
vps37a
vacuolar protein sorting 37A
chr19_+_19767567 0.28 ENSDART00000169074
hoxa3a
homeobox A3a
chr8_+_52637507 0.28 ENSDART00000163830
si:dkey-90l8.3
si:dkey-90l8.3
chr1_-_26062798 0.28 ENSDART00000185348
pdcd4a
programmed cell death 4a
chr13_-_46882267 0.28 ENSDART00000161322
slc29a1a
solute carrier family 29 (equilibrative nucleoside transporter), member 1a
chr18_+_3338228 0.28 ENSDART00000161520
gdpd4a
glycerophosphodiester phosphodiesterase domain containing 4a
chr5_-_13685047 0.27 ENSDART00000018351
zgc:65851
zgc:65851
chr13_+_25486608 0.27 ENSDART00000057689
bag3
BCL2 associated athanogene 3
chr5_+_20103085 0.27 ENSDART00000079424
si:rp71-1c23.3
si:rp71-1c23.3
chr17_-_44584811 0.27 ENSDART00000165059
ENSDART00000165252
slc35f4
solute carrier family 35, member F4
chr3_-_9458445 0.27 ENSDART00000192712
FO904885.1

chr14_+_48045193 0.26 ENSDART00000124773
ppid
peptidylprolyl isomerase D
chr6_-_40697585 0.26 ENSDART00000113196
si:ch211-157b11.14
si:ch211-157b11.14
chr19_+_3842891 0.26 ENSDART00000159043
lsm10
LSM10, U7 small nuclear RNA associated
chr10_+_26813710 0.25 ENSDART00000136122
si:ch211-263p13.7
si:ch211-263p13.7
chr10_-_26273629 0.24 ENSDART00000147790
dchs1b
dachsous cadherin-related 1b
chr8_+_22931427 0.24 ENSDART00000063096
sypa
synaptophysin a
chr2_+_20866898 0.24 ENSDART00000150086
odr4
odr-4 GPCR localization factor homolog
chr16_-_29375986 0.24 ENSDART00000167132
isg20l2
interferon stimulated exonuclease gene 20-like 2
chr6_-_29159888 0.24 ENSDART00000110288
zbtb11
zinc finger and BTB domain containing 11
chr23_-_44494401 0.24 ENSDART00000114640
ENSDART00000148532
actl6b
actin-like 6B
chr2_-_48966431 0.24 ENSDART00000147948
kcnj9
potassium inwardly-rectifying channel, subfamily J, member 9
chr5_+_32791245 0.23 ENSDART00000077189
ier5l
immediate early response 5-like
chr4_-_17055950 0.23 ENSDART00000162945
sox5
SRY (sex determining region Y)-box 5
chr5_-_63083283 0.23 ENSDART00000185337
BX927212.1

chr22_+_24389135 0.22 ENSDART00000157861
p3h2
prolyl 3-hydroxylase 2
chr24_-_21131607 0.22 ENSDART00000010126
zdhhc23b
zinc finger, DHHC-type containing 23b
chr2_+_24199073 0.22 ENSDART00000144110
map4l
microtubule associated protein 4 like
chr18_+_50907675 0.21 ENSDART00000159950
si:ch1073-450f2.1
si:ch1073-450f2.1
chr6_+_16406723 0.21 ENSDART00000040035
ccdc80l1
coiled-coil domain containing 80 like 1
chr3_-_44012748 0.20 ENSDART00000167248
ENSDART00000157463
ENSDART00000159111
il4r.1
interleukin 4 receptor, tandem duplicate 1
chr6_-_57655299 0.20 ENSDART00000083807
cbfa2t2
core-binding factor, runt domain, alpha subunit 2; translocated to, 2
chr18_-_28938912 0.20 ENSDART00000136201
si:ch211-174j14.2
si:ch211-174j14.2
chr19_+_33139164 0.19 ENSDART00000043039
fam84b
family with sequence similarity 84, member B
chr11_-_18468570 0.19 ENSDART00000155474
ENSDART00000193869
fgd5a
FYVE, RhoGEF and PH domain containing 5a
chr16_+_28270037 0.18 ENSDART00000059035
mindy3
MINDY lysine 48 deubiquitinase 3
chr10_+_19039507 0.18 ENSDART00000193538
ENSDART00000111952
ENSDART00000180093
igsf9a
immunoglobulin superfamily, member 9a
chr21_-_36948 0.18 ENSDART00000181230
JMY
junction mediating and regulatory protein, p53 cofactor
chr11_+_2180072 0.17 ENSDART00000186854
ENSDART00000164839
hoxc11b
homeobox C11b
chr6_-_40286633 0.17 ENSDART00000033844
col7a1
collagen, type VII, alpha 1
chr1_+_53714734 0.17 ENSDART00000114689
pus10
pseudouridylate synthase 10
chr9_+_44430705 0.17 ENSDART00000190696
ppp1r1c
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr19_+_35799384 0.16 ENSDART00000076023
angpt2b
angiopoietin 2b
chr13_-_13751017 0.16 ENSDART00000180182
ky
kyphoscoliosis peptidase
chr6_+_40723554 0.16 ENSDART00000103833
slc26a6l
solute carrier family 26, member 6, like
chr5_-_23999777 0.16 ENSDART00000085969
map7d2a
MAP7 domain containing 2a
chr9_+_6802641 0.16 ENSDART00000187278
FO203514.1

chr5_-_30176970 0.16 ENSDART00000098300
adamts8a
ADAM metallopeptidase with thrombospondin type 1 motif, 8a
chr7_-_28463106 0.16 ENSDART00000137799
trim66
tripartite motif containing 66
chr3_-_36612877 0.15 ENSDART00000167164
si:dkeyp-72e1.7
si:dkeyp-72e1.7
chr17_+_28340138 0.15 ENSDART00000033943
mdga2a
MAM domain containing glycosylphosphatidylinositol anchor 2a
chr14_+_36223097 0.15 ENSDART00000186872
pitx2
paired-like homeodomain 2
chr13_+_4439074 0.15 ENSDART00000192055
tbxtb
T-box transcription factor Tb
chr10_-_11397590 0.15 ENSDART00000064212
srek1ip1
SREK1-interacting protein 1
chr8_+_26083808 0.14 ENSDART00000099283
dalrd3
DALR anticodon binding domain containing 3
chr18_+_8346920 0.14 ENSDART00000083421
cpt1b
carnitine palmitoyltransferase 1B (muscle)
chr17_-_33405301 0.14 ENSDART00000157089
BX323819.1

chr22_-_4742866 0.14 ENSDART00000177992
CR751224.1

chr2_+_24199276 0.14 ENSDART00000140575
map4l
microtubule associated protein 4 like
chr19_-_10656667 0.13 ENSDART00000081379
ENSDART00000151456
ENSDART00000143271
ENSDART00000182126
olah
oleoyl-ACP hydrolase
chr21_+_20383837 0.13 ENSDART00000026430
hspb11
heat shock protein, alpha-crystallin-related, b11
chr4_-_43822179 0.13 ENSDART00000185246
si:dkey-261p22.1
si:dkey-261p22.1
chr4_+_5848229 0.13 ENSDART00000161101
ENSDART00000067357
lyrm5a
LYR motif containing 5a
chr10_+_21776911 0.13 ENSDART00000163077
ENSDART00000186093
pcdh1g22
protocadherin 1 gamma 22
chr25_-_8030113 0.13 ENSDART00000104674
camk1db
calcium/calmodulin-dependent protein kinase 1Db
chr9_+_32301017 0.13 ENSDART00000127916
ENSDART00000183298
ENSDART00000143103
hspe1
heat shock 10 protein 1
chr9_+_6587364 0.13 ENSDART00000122279
fhl2a
four and a half LIM domains 2a
chr9_+_6587056 0.13 ENSDART00000193421
fhl2a
four and a half LIM domains 2a
chr24_-_21808816 0.13 ENSDART00000025621
ENSDART00000130446
flt1
fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)
chr5_-_56416188 0.13 ENSDART00000146773
acaca
acetyl-CoA carboxylase alpha
chr11_-_5939861 0.13 ENSDART00000110033
abhd8b
abhydrolase domain containing 8b
chr20_+_34543365 0.13 ENSDART00000152073
si:ch211-242b18.1
si:ch211-242b18.1
chr7_+_21272833 0.13 ENSDART00000052942
serpinh2
serine (or cysteine) peptidase inhibitor, clade H, member 2
chr23_-_39738055 0.12 ENSDART00000137859
htr6
5-hydroxytryptamine (serotonin) receptor 6
chr6_+_9175886 0.12 ENSDART00000165333
si:ch211-207l14.1
si:ch211-207l14.1
chr2_-_6482240 0.12 ENSDART00000132623
rgs13
regulator of G protein signaling 13
chr17_-_31044803 0.12 ENSDART00000185941
ENSDART00000152016
eml1
echinoderm microtubule associated protein like 1
chr2_-_35103069 0.11 ENSDART00000111730
pappa2
pappalysin 2
chr23_-_6879731 0.11 ENSDART00000082154
trim35-39
tripartite motif containing 35-39
chr24_+_20969358 0.11 ENSDART00000129675
drd3
dopamine receptor D3
chr14_+_25817246 0.11 ENSDART00000136733
glra1
glycine receptor, alpha 1
chr6_+_13333133 0.10 ENSDART00000038505
rprmb
reprimo, TP53 dependent G2 arrest mediator candidate b
chr23_-_44903048 0.10 ENSDART00000149103
fhdc5
FH2 domain containing 5
chr6_+_46341306 0.10 ENSDART00000111905
BX649498.1

chr2_-_45504798 0.10 ENSDART00000131412
gpsm2
G protein signaling modulator 2
chr22_+_2229964 0.09 ENSDART00000112582
znf1161
zinc finger protein 1161
chr10_-_24416471 0.09 ENSDART00000135985
hephl1b
hephaestin-like 1b
chr25_+_28679672 0.09 ENSDART00000139965
ENSDART00000134072
cnot2
CCR4-NOT transcription complex, subunit 2
chr1_-_47431453 0.09 ENSDART00000101104
gja5b
gap junction protein, alpha 5b
chr14_-_2318590 0.09 ENSDART00000192735
pcdh2ab8
protocadherin 2 alpha b 8
chr7_+_29955368 0.09 ENSDART00000173686
tpma
alpha-tropomyosin
chr9_+_32301456 0.09 ENSDART00000078608
ENSDART00000185153
ENSDART00000144947
hspe1
heat shock 10 protein 1
chr19_+_23301050 0.09 ENSDART00000193713
si:dkey-79i2.4
si:dkey-79i2.4
chr8_+_28467893 0.09 ENSDART00000189724
slc52a3
solute carrier family 52 (riboflavin transporter), member 3
chr8_-_13013123 0.08 ENSDART00000147802
dennd2da
DENN/MADD domain containing 2Da
chr1_-_9644630 0.08 ENSDART00000123725
ENSDART00000161164
ugt5b3
UDP glucuronosyltransferase 5 family, polypeptide B3
chr17_+_41463942 0.08 ENSDART00000075331
insm1b
insulinoma-associated 1b
chr8_-_15991801 0.08 ENSDART00000132005
agbl4
ATP/GTP binding protein-like 4
chr12_-_37941733 0.08 ENSDART00000130167
CABZ01046949.1

chr13_-_9875538 0.08 ENSDART00000041609
tm9sf3
transmembrane 9 superfamily member 3
chr15_-_29012493 0.08 ENSDART00000060018
dharma
dharma
chr16_-_6821927 0.08 ENSDART00000149070
ENSDART00000149570
mbpb
myelin basic protein b
chr11_+_30000814 0.07 ENSDART00000191011
ENSDART00000189770
nhsb
Nance-Horan syndrome b (congenital cataracts and dental anomalies)
chr25_+_28272908 0.07 ENSDART00000010325
fezf1
FEZ family zinc finger 1
chr14_+_22022441 0.07 ENSDART00000149121
clcf1
cardiotrophin-like cytokine factor 1
chr5_-_30475011 0.07 ENSDART00000187501
phldb1a
pleckstrin homology-like domain, family B, member 1a
chr10_-_36738619 0.07 ENSDART00000093000
ENSDART00000157179
PLEKHB1
si:ch211-176g13.7
chr21_+_5926777 0.07 ENSDART00000121769
rexo4
REX4 homolog, 3'-5' exonuclease
chr18_+_38321039 0.07 ENSDART00000132534
ENSDART00000111260
ENSDART00000192806
alx4b
ALX homeobox 4b
chr23_-_24047054 0.07 ENSDART00000184308
ENSDART00000185902
CR925720.1

chr17_+_21964472 0.07 ENSDART00000063704
ENSDART00000188904
crip3
cysteine-rich protein 3
chr19_+_14158075 0.07 ENSDART00000170335
ENSDART00000168260
nudc
nudC nuclear distribution protein
chr8_+_25342896 0.06 ENSDART00000129032
CR847543.1

chr3_+_24634481 0.06 ENSDART00000163080
si:dkey-68o6.8
si:dkey-68o6.8
chr4_+_8168514 0.06 ENSDART00000150830
ninj2
ninjurin 2
chr17_-_42213285 0.06 ENSDART00000140549
nkx2.2a
NK2 homeobox 2a
chr22_+_18886209 0.06 ENSDART00000144402
fstl3
follistatin-like 3 (secreted glycoprotein)
chr6_-_13401133 0.06 ENSDART00000151206
fmnl2b
formin-like 2b
chr16_-_32208728 0.06 ENSDART00000023995
calhm5.2
calcium homeostasis modulator family member 5, tandem duplicate 2
chr20_-_27864964 0.06 ENSDART00000153311
syndig1l
synapse differentiation inducing 1-like
chr9_+_53707240 0.06 ENSDART00000171490
PCDH8
si:ch211-199f5.1
chr25_+_30442389 0.06 ENSDART00000003346
pdcd2l
programmed cell death 2-like

Network of associatons between targets according to the STRING database.

First level regulatory network of si:dkey-18a10.3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0061178 insulin secretion involved in cellular response to glucose stimulus(GO:0035773) regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.3 1.0 GO:0090219 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553) negative regulation of lipid kinase activity(GO:0090219)
0.2 0.6 GO:1902410 mitotic cytokinetic process(GO:1902410) mitotic cleavage furrow formation(GO:1903673)
0.2 0.7 GO:1903428 regulation of nitric oxide biosynthetic process(GO:0045428) positive regulation of nitric oxide biosynthetic process(GO:0045429) positive regulation of reactive oxygen species biosynthetic process(GO:1903428) positive regulation of nitric oxide metabolic process(GO:1904407)
0.1 0.6 GO:0045124 regulation of bone resorption(GO:0045124)
0.1 1.0 GO:0043490 acidic amino acid transport(GO:0015800) aspartate transport(GO:0015810) L-glutamate transport(GO:0015813) malate-aspartate shuttle(GO:0043490)
0.1 0.4 GO:0006168 adenine salvage(GO:0006168)
0.1 0.4 GO:0006598 polyamine catabolic process(GO:0006598) putrescine catabolic process(GO:0009447)
0.1 0.6 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065)
0.1 0.5 GO:0006953 acute-phase response(GO:0006953)
0.1 0.3 GO:0010662 negative regulation of muscle cell apoptotic process(GO:0010656) muscle cell apoptotic process(GO:0010657) striated muscle cell apoptotic process(GO:0010658) regulation of muscle cell apoptotic process(GO:0010660) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664)
0.1 1.0 GO:1902108 regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902108)
0.1 0.3 GO:0086005 ventricular cardiac muscle cell action potential(GO:0086005)
0.1 1.4 GO:0033555 multicellular organismal response to stress(GO:0033555)
0.1 0.3 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.1 0.3 GO:0060017 parathyroid gland development(GO:0060017)
0.1 0.7 GO:0050936 xanthophore differentiation(GO:0050936)
0.1 0.7 GO:0051597 response to methylmercury(GO:0051597)
0.1 0.2 GO:0021611 facial nerve formation(GO:0021611)
0.0 0.2 GO:0002532 production of molecular mediator involved in inflammatory response(GO:0002532)
0.0 0.3 GO:0015864 uridine transport(GO:0015862) pyrimidine nucleoside transport(GO:0015864)
0.0 0.7 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 1.1 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.2 GO:0048014 Tie signaling pathway(GO:0048014)
0.0 0.9 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.4 GO:0001678 cellular glucose homeostasis(GO:0001678)
0.0 0.6 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208)
0.0 0.1 GO:0071361 cellular response to ethanol(GO:0071361)
0.0 0.7 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.1 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.0 0.2 GO:0061072 iris morphogenesis(GO:0061072)
0.0 0.2 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 0.8 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.2 GO:0051454 pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.0 1.2 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 0.4 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.1 GO:0021530 spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.0 0.3 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.0 0.8 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.0 0.5 GO:0003171 atrioventricular valve development(GO:0003171)
0.0 0.3 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 0.4 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 0.3 GO:0014823 response to activity(GO:0014823)
0.0 0.1 GO:0032218 riboflavin transport(GO:0032218)
0.0 0.1 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.0 0.3 GO:0048246 macrophage chemotaxis(GO:0048246)
0.0 0.1 GO:1902262 apoptotic process involved in patterning of blood vessels(GO:1902262)
0.0 0.1 GO:0036368 cone photoresponse recovery(GO:0036368)
0.0 0.1 GO:0048680 positive regulation of axon regeneration(GO:0048680) positive regulation of neuron projection regeneration(GO:0070572)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.1 0.6 GO:0098642 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.1 0.3 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.1 0.6 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.8 GO:0043209 myelin sheath(GO:0043209)
0.0 0.5 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.3 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.6 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.3 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.9 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.3 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.3 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 1.0 GO:0031514 motile cilium(GO:0031514)
0.0 0.2 GO:0035267 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 0.6 GO:0016342 catenin complex(GO:0016342)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.4 GO:0004977 melanocortin receptor activity(GO:0004977)
0.1 0.4 GO:0003999 adenine phosphoribosyltransferase activity(GO:0003999)
0.1 0.3 GO:0004031 aldehyde oxidase activity(GO:0004031) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.1 0.4 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.1 0.6 GO:0070698 type I activin receptor binding(GO:0070698)
0.1 1.0 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.1 1.7 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 0.4 GO:0005536 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) glucose binding(GO:0005536) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 0.6 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.1 0.4 GO:0019808 polyamine binding(GO:0019808) spermidine binding(GO:0019809)
0.1 0.2 GO:0019797 procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.1 0.6 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 1.8 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.6 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.3 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.3 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 1.0 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.6 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.1 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.0 0.2 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.6 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.3 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.2 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.1 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 0.6 GO:0051087 chaperone binding(GO:0051087)
0.0 0.9 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.5 GO:0004312 fatty acid synthase activity(GO:0004312)
0.0 0.1 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.0 0.3 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.4 GO:0015379 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.0 0.8 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.1 GO:0032217 riboflavin transporter activity(GO:0032217)
0.0 1.1 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.6 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.3 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.1 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.1 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.2 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.1 0.5 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 1.3 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.3 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.6 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.1 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.4 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 0.8 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.4 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.6 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 1.3 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.3 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.3 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.3 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.1 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 1.4 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.1 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.1 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.0 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.2 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.4 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport