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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for si:dkey-43p13.5+uncx

Z-value: 0.26

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Transcription factors associated with si:dkey-43p13.5+uncx

Gene Symbol Gene ID Gene Info
uncx
ENSDARG00000102976 UNC homeobox
si_dkey-43p13.5
ENSDARG00000104199 si_dkey-43p13.5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
si:dkey-43p13.5dr11_v1_chr3_+_43086548_430865480.929.1e-08Click!
uncxdr11_v1_chr3_-_43356082_433560820.097.3e-01Click!

Activity profile of si:dkey-43p13.5+uncx motif

Sorted Z-values of si:dkey-43p13.5+uncx motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr21_+_25777425 1.35 ENSDART00000021620
cldnd
claudin d
chr11_-_6452444 1.33 ENSDART00000137879
ENSDART00000134957
ENSDART00000004483
larp6b
La ribonucleoprotein domain family, member 6b
chr10_-_21362071 0.99 ENSDART00000125167
avd
avidin
chr9_+_8396755 0.92 ENSDART00000043067
zgc:171776
zgc:171776
chr10_-_21362320 0.92 ENSDART00000189789
avd
avidin
chr8_+_45334255 0.88 ENSDART00000126848
ENSDART00000134161
ENSDART00000142322
ENSDART00000145011
ENSDART00000183560
pabpc1l
poly(A) binding protein, cytoplasmic 1-like
chr10_-_8053753 0.87 ENSDART00000162289
si:ch211-251f6.7
si:ch211-251f6.7
chr24_-_2450597 0.82 ENSDART00000188080
ENSDART00000093331
rreb1a
ras responsive element binding protein 1a
chr16_+_29509133 0.82 ENSDART00000112116
ctss2.1
cathepsin S, ortholog2, tandem duplicate 1
chr1_-_55248496 0.80 ENSDART00000098615
nanos3
nanos homolog 3
chr2_-_17115256 0.79 ENSDART00000190488
pif1
PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)
chr18_-_40708537 0.79 ENSDART00000077577
si:ch211-132b12.8
si:ch211-132b12.8
chr14_-_33481428 0.79 ENSDART00000147059
ENSDART00000140001
ENSDART00000124242
ENSDART00000164836
ENSDART00000190104
ENSDART00000186833
ENSDART00000180873
lamp2
lysosomal-associated membrane protein 2
chr12_-_14143344 0.77 ENSDART00000152742
buc2l
bucky ball 2-like
chr11_+_18183220 0.75 ENSDART00000113468
LO018315.10

chr10_-_34916208 0.74 ENSDART00000187371
ccna1
cyclin A1
chr22_+_17828267 0.73 ENSDART00000136016
hapln4
hyaluronan and proteoglycan link protein 4
chr24_-_9997948 0.71 ENSDART00000136274
si:ch211-146l10.7
si:ch211-146l10.7
chr1_-_18811517 0.71 ENSDART00000142026
si:dkey-167i21.2
si:dkey-167i21.2
chr10_-_25217347 0.68 ENSDART00000036906
kpna7
karyopherin alpha 7 (importin alpha 8)
chr5_+_37903790 0.67 ENSDART00000162470
tmprss4b
transmembrane protease, serine 4b
chr18_+_50880096 0.64 ENSDART00000169782
si:ch1073-450f2.1
si:ch1073-450f2.1
chr5_-_68333081 0.63 ENSDART00000168786
h1m
linker histone H1M
chr7_-_51773166 0.61 ENSDART00000054591
bmp15
bone morphogenetic protein 15
chr10_-_8046764 0.57 ENSDART00000099031
zgc:136254
zgc:136254
chr10_-_34915886 0.56 ENSDART00000141201
ENSDART00000002166
ccna1
cyclin A1
chr16_-_29387215 0.56 ENSDART00000148787
s100a1
S100 calcium binding protein A1
chr20_-_23426339 0.56 ENSDART00000004625
zar1
zygote arrest 1
chr24_+_12835935 0.55 ENSDART00000114762
nanog
nanog homeobox
chr23_+_28322986 0.54 ENSDART00000134710
birc5b
baculoviral IAP repeat containing 5b
chr1_-_33645967 0.53 ENSDART00000192758
cldng
claudin g
chr2_+_41526904 0.52 ENSDART00000127520
acvr1l
activin A receptor, type 1 like
chr4_+_9467049 0.51 ENSDART00000012659
zgc:55888
zgc:55888
chr14_+_34492288 0.50 ENSDART00000144301
wnt8a
wingless-type MMTV integration site family, member 8a
chr11_-_1550709 0.49 ENSDART00000110097
si:ch73-303b9.1
si:ch73-303b9.1
chr8_+_16758304 0.48 ENSDART00000133514
elovl7a
ELOVL fatty acid elongase 7a
chr17_-_4245902 0.47 ENSDART00000151851
gdf3
growth differentiation factor 3
chr25_+_5972690 0.45 ENSDART00000067517
si:ch211-11i22.4
si:ch211-11i22.4
chr13_+_33462232 0.45 ENSDART00000177841
zgc:136302
zgc:136302
chr17_+_16046132 0.44 ENSDART00000155005
si:ch73-204p21.2
si:ch73-204p21.2
chr11_+_18175893 0.44 ENSDART00000177625
zgc:173545
zgc:173545
chr18_+_39487486 0.43 ENSDART00000126978
acadl
acyl-CoA dehydrogenase long chain
chr7_+_24528430 0.43 ENSDART00000133022
si:dkeyp-75h12.2
si:dkeyp-75h12.2
chr20_-_6532462 0.43 ENSDART00000054653
mcm3l
MCM3 minichromosome maintenance deficient 3 (S. cerevisiae), like
chr12_-_18577983 0.43 ENSDART00000193262
zdhhc4
zinc finger, DHHC-type containing 4
chr2_+_6253246 0.43 ENSDART00000058256
ENSDART00000076700
zp3b
zona pellucida glycoprotein 3b
chr11_-_44801968 0.42 ENSDART00000161846
map1lc3c
microtubule-associated protein 1 light chain 3 gamma
chr11_-_35171768 0.42 ENSDART00000192896
traip
TRAF-interacting protein
chr16_+_47207691 0.42 ENSDART00000062507
ica1
islet cell autoantigen 1
chr3_+_7808459 0.41 ENSDART00000162374
hook2
hook microtubule-tethering protein 2
chr8_+_11425048 0.40 ENSDART00000018739
tjp2b
tight junction protein 2b (zona occludens 2)
chr2_-_38287987 0.40 ENSDART00000185329
ENSDART00000061677
si:ch211-14a17.6
si:ch211-14a17.6
chr17_+_16046314 0.40 ENSDART00000154554
ENSDART00000154338
ENSDART00000155336
si:ch73-204p21.2
si:ch73-204p21.2
chr1_+_21937201 0.39 ENSDART00000087729
kdm4c
lysine (K)-specific demethylase 4C
chr10_-_36691681 0.39 ENSDART00000122375
mrpl48
mitochondrial ribosomal protein L48
chr24_-_5713799 0.39 ENSDART00000137293
dia1b
deleted in autism 1b
chr10_+_15255198 0.39 ENSDART00000139047
ENSDART00000172107
ENSDART00000183413
ENSDART00000185314
vldlr
very low density lipoprotein receptor
chr10_+_16036246 0.39 ENSDART00000141586
ENSDART00000135868
ENSDART00000065037
ENSDART00000124502
lmnb1
lamin B1
chr1_+_12295142 0.39 ENSDART00000158595
gne
glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
chr10_+_1849874 0.38 ENSDART00000158897
ENSDART00000149956
apc
adenomatous polyposis coli
chr18_+_20560616 0.38 ENSDART00000136710
ENSDART00000151974
ENSDART00000121699
ENSDART00000040074
wee2
WEE1 homolog 2 (S. pombe)
chr15_-_1038193 0.38 ENSDART00000159462
si:dkey-77f5.3
si:dkey-77f5.3
chr22_-_17653143 0.37 ENSDART00000089171
hmha1b
histocompatibility (minor) HA-1 b
chr16_-_17197546 0.37 ENSDART00000139939
ENSDART00000135146
ENSDART00000063800
ENSDART00000163606
gapdh
glyceraldehyde-3-phosphate dehydrogenase
chr24_-_31904924 0.37 ENSDART00000156060
ENSDART00000129741
ENSDART00000154276
si:ch73-78o10.1
si:ch73-78o10.1
chr19_-_29887629 0.36 ENSDART00000066123
kpna6
karyopherin alpha 6 (importin alpha 7)
chr10_+_15024772 0.35 ENSDART00000135667
si:dkey-88l16.5
si:dkey-88l16.5
chr16_-_54919260 0.35 ENSDART00000156533
kdf1a
keratinocyte differentiation factor 1a
chr22_-_22147375 0.35 ENSDART00000149304
cdc34a
cell division cycle 34 homolog (S. cerevisiae) a
chr3_+_28860283 0.35 ENSDART00000077235
alg1
ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase
chr21_+_13383413 0.35 ENSDART00000151345
zgc:113162
zgc:113162
chr7_+_24023653 0.34 ENSDART00000141165
tinf2
TERF1 (TRF1)-interacting nuclear factor 2
chr17_+_21902058 0.34 ENSDART00000142178
plekha1a
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1a
chr10_+_11261576 0.34 ENSDART00000155333
hsdl2
hydroxysteroid dehydrogenase like 2
chr3_-_32337653 0.34 ENSDART00000156918
ENSDART00000156551
si:dkey-16p21.8
si:dkey-16p21.8
chr9_-_712308 0.34 ENSDART00000144625
ndufb3
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3
chr3_+_17933132 0.33 ENSDART00000104299
ENSDART00000162144
ENSDART00000162242
ENSDART00000166289
ENSDART00000171101
ENSDART00000164853
cnp
2',3'-cyclic nucleotide 3' phosphodiesterase
chr22_-_17652914 0.33 ENSDART00000138483
si:ch73-243b8.4
si:ch73-243b8.4
chr14_+_8940326 0.33 ENSDART00000159920
rps6kal
ribosomal protein S6 kinase a, like
chr3_-_61494840 0.33 ENSDART00000101957
baiap2l1b
BAI1-associated protein 2-like 1b
chr3_-_30488063 0.33 ENSDART00000055393
ENSDART00000151367
med25
mediator complex subunit 25
chr3_+_18807006 0.33 ENSDART00000180091
tnpo2
transportin 2 (importin 3, karyopherin beta 2b)
chr7_+_59033902 0.32 ENSDART00000168888
fastkd3
FAST kinase domains 3
chr3_-_4663602 0.32 ENSDART00000083532
slc25a38a
solute carrier family 25, member 38a
chr19_+_40069524 0.31 ENSDART00000151365
ENSDART00000140926
zmym4
zinc finger, MYM-type 4
chr6_-_40778294 0.31 ENSDART00000019845
arpc4
actin related protein 2/3 complex, subunit 4
chr8_-_25034411 0.31 ENSDART00000135973
nfyal
nuclear transcription factor Y, alpha, like
chr5_-_63302944 0.31 ENSDART00000047110
gsnb
gelsolin b
chr22_+_39096911 0.31 ENSDART00000157127
ENSDART00000153841
lmcd1
LIM and cysteine-rich domains 1
chr14_+_31496543 0.30 ENSDART00000170683
phf6
PHD finger protein 6
chr17_-_24575893 0.29 ENSDART00000141914
aftphb
aftiphilin b
chr21_+_34088110 0.29 ENSDART00000145123
ENSDART00000029599
ENSDART00000147519
mtmr1b
myotubularin related protein 1b
chr1_-_45215343 0.29 ENSDART00000014727
ddx39aa
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39Aa
chr24_-_6024466 0.29 ENSDART00000040865
pdss1
prenyl (decaprenyl) diphosphate synthase, subunit 1
chr23_-_36303216 0.29 ENSDART00000188720
cbx5
chromobox homolog 5 (HP1 alpha homolog, Drosophila)
chr24_-_25166720 0.29 ENSDART00000141601
phldb2b
pleckstrin homology-like domain, family B, member 2b
chr15_+_24676905 0.29 ENSDART00000078014
ENSDART00000143137
poldip2
polymerase (DNA-directed), delta interacting protein 2
chr14_+_34490445 0.29 ENSDART00000132193
ENSDART00000148044
wnt8a
wingless-type MMTV integration site family, member 8a
chr8_-_20230559 0.29 ENSDART00000193677
mllt1a
MLLT1, super elongation complex subunit a
chr20_-_51831657 0.29 ENSDART00000165076
mia3
melanoma inhibitory activity family, member 3
chr17_-_40956035 0.28 ENSDART00000124715
si:dkey-16j16.4
si:dkey-16j16.4
chr7_+_34487833 0.28 ENSDART00000173854
cln6a
CLN6, transmembrane ER protein a
chr20_-_14114078 0.28 ENSDART00000168434
ENSDART00000104032
si:ch211-223m11.2
si:ch211-223m11.2
chr9_+_45428041 0.28 ENSDART00000193087
adarb1b
adenosine deaminase, RNA-specific, B1b
chr8_+_3431671 0.28 ENSDART00000017850
ctu1
cytosolic thiouridylase subunit 1 homolog (S. pombe)
chr12_+_1609563 0.28 ENSDART00000163559
SLC39A11
solute carrier family 39 member 11
chr22_-_20695237 0.28 ENSDART00000112722
org
oogenesis-related gene
chr4_+_13586689 0.28 ENSDART00000067161
ENSDART00000138201
tnpo3
transportin 3
chr19_+_32979331 0.28 ENSDART00000078066
spire1a
spire-type actin nucleation factor 1a
chr6_-_18228358 0.27 ENSDART00000167937
p4hb
prolyl 4-hydroxylase, beta polypeptide
chr5_-_15283509 0.27 ENSDART00000052712
gnb1l
guanine nucleotide binding protein (G protein), beta polypeptide 1-like
chr11_-_35171162 0.27 ENSDART00000017393
traip
TRAF-interacting protein
chr20_-_34028967 0.27 ENSDART00000153408
ENSDART00000033817
scyl3
SCY1-like, kinase-like 3
chr22_-_23267893 0.27 ENSDART00000105613
si:dkey-121a9.3
si:dkey-121a9.3
chr1_+_35985813 0.26 ENSDART00000179634
ENSDART00000139636
ENSDART00000175902
zgc:152968
zgc:152968
chr24_-_24724233 0.26 ENSDART00000127044
ENSDART00000012399
armc1
armadillo repeat containing 1
chr8_-_1838315 0.26 ENSDART00000114476
ENSDART00000140077
pi4kab
phosphatidylinositol 4-kinase, catalytic, alpha b
chr3_+_22035863 0.26 ENSDART00000177169
cdc27
cell division cycle 27
chr9_-_21238159 0.26 ENSDART00000146764
ENSDART00000102143
cox17
COX17 cytochrome c oxidase copper chaperone
chr12_-_3978306 0.26 ENSDART00000149473
ENSDART00000114857
ppp4cb
protein phosphatase 4, catalytic subunit b
chr20_-_20931197 0.26 ENSDART00000152726
btbd6b
BTB (POZ) domain containing 6b
chr15_-_2519640 0.26 ENSDART00000047013
srprb
signal recognition particle receptor, B subunit
chr7_-_26270014 0.26 ENSDART00000079347
serpine1
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
chr21_-_32060993 0.26 ENSDART00000131651
si:ch211-160j14.2
si:ch211-160j14.2
chr20_-_38787341 0.26 ENSDART00000136771
dnajc5ga
DnaJ (Hsp40) homolog, subfamily C, member 5 gamma a
chr15_-_34408777 0.25 ENSDART00000139934
agmo
alkylglycerol monooxygenase
chr6_+_36839509 0.25 ENSDART00000190605
ENSDART00000104160
zgc:110788
zgc:110788
chr23_-_20051369 0.25 ENSDART00000049836
bgnb
biglycan b
chr23_-_36446307 0.25 ENSDART00000136623
zgc:174906
zgc:174906
chr12_+_38563373 0.25 ENSDART00000134670
ENSDART00000193668
ttyh2
tweety family member 2
chr19_-_25113660 0.25 ENSDART00000035538
ptp4a3
protein tyrosine phosphatase type IVA, member 3
chr14_+_35428152 0.25 ENSDART00000172597
sytl4
synaptotagmin-like 4
chr8_-_20230802 0.25 ENSDART00000063400
mllt1a
MLLT1, super elongation complex subunit a
chr11_+_11303458 0.25 ENSDART00000162486
ENSDART00000160703
si:dkey-23f9.4
si:dkey-23f9.4
chr4_+_13586455 0.25 ENSDART00000187230
tnpo3
transportin 3
chr2_+_15048410 0.25 ENSDART00000058484
cnn3b
calponin 3, acidic b
chr21_+_4508959 0.24 ENSDART00000140432
ENSDART00000147187
ENSDART00000148910
phyhd1
phytanoyl-CoA dioxygenase domain containing 1
chr7_+_22313533 0.24 ENSDART00000123457
TMEM102
si:dkey-11f12.2
chr2_-_7246848 0.24 ENSDART00000146434
zgc:153115
zgc:153115
chr23_+_2704793 0.24 ENSDART00000147953
ncoa6
nuclear receptor coactivator 6
chr20_+_14114258 0.24 ENSDART00000044937
kcns3b
potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3b
chr8_+_21254192 0.24 ENSDART00000167718
itpr3
inositol 1,4,5-trisphosphate receptor, type 3
chr14_-_25935167 0.24 ENSDART00000139855
g3bp1
GTPase activating protein (SH3 domain) binding protein 1
chr2_+_1714640 0.24 ENSDART00000086761
ENSDART00000111613
adgrl2b.1
adgrl2b.1
adhesion G protein-coupled receptor L2b, tandem duplicate 1
adhesion G protein-coupled receptor L2b, tandem duplicate 1
chr15_-_17169935 0.24 ENSDART00000110111
cul5a
cullin 5a
chr20_+_19006703 0.24 ENSDART00000128435
pinx1
PIN2/TERF1 interacting, telomerase inhibitor 1
chr4_+_4849789 0.24 ENSDART00000130818
ENSDART00000127751
ptprz1b
protein tyrosine phosphatase, receptor-type, Z polypeptide 1b
chr1_+_6225493 0.24 ENSDART00000145378
fastkd2
FAST kinase domains 2
chr23_+_2789422 0.24 ENSDART00000156954
plcg1
phospholipase C, gamma 1
chr6_+_40922572 0.24 ENSDART00000133599
ENSDART00000002728
ENSDART00000145153
eif4enif1
eukaryotic translation initiation factor 4E nuclear import factor 1
chr24_-_11076400 0.24 ENSDART00000003195
chmp4c
charged multivesicular body protein 4C
chr14_-_33945692 0.23 ENSDART00000168546
ENSDART00000189778
zdhhc24
zinc finger, DHHC-type containing 24
chr6_-_15065376 0.23 ENSDART00000087797
tgfbrap1
transforming growth factor, beta receptor associated protein 1
chr13_-_32726178 0.23 ENSDART00000012232
pdss2
prenyl (decaprenyl) diphosphate synthase, subunit 2
chr19_-_432083 0.23 ENSDART00000165371
dus3l
dihydrouridine synthase 3-like (S. cerevisiae)
chr22_-_20924564 0.23 ENSDART00000100642
ENSDART00000032770
ell
elongation factor RNA polymerase II
chr12_+_16087077 0.23 ENSDART00000141898
znf281b
zinc finger protein 281b
chr14_-_26392146 0.23 ENSDART00000037999
b4galt7
xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7 (galactosyltransferase I)
chr5_+_41476443 0.23 ENSDART00000145228
ENSDART00000137981
ENSDART00000142538
pias2
protein inhibitor of activated STAT, 2
chr11_+_12811906 0.23 ENSDART00000123445
rtel1
regulator of telomere elongation helicase 1
chr2_+_42871831 0.23 ENSDART00000171393
efr3a
EFR3 homolog A (S. cerevisiae)
chr10_+_7709724 0.22 ENSDART00000097670
ggcx
gamma-glutamyl carboxylase
chr1_+_5422439 0.22 ENSDART00000055047
ENSDART00000142248
stk16
serine/threonine kinase 16
chr23_+_20431140 0.22 ENSDART00000193950
slc35c2
solute carrier family 35 (GDP-fucose transporter), member C2
chr10_+_43039947 0.22 ENSDART00000193434
atg10
ATG10 autophagy related 10 homolog (S. cerevisiae)
chr19_+_15440841 0.22 ENSDART00000182329
lin28a
lin-28 homolog A (C. elegans)
chr2_+_26237322 0.22 ENSDART00000030520
palm1b
paralemmin 1b
chr19_+_29808471 0.22 ENSDART00000186428
hdac1
histone deacetylase 1
chr6_-_12172424 0.21 ENSDART00000109344
tanc1a
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1a
chr10_+_8197827 0.21 ENSDART00000026244
mtrex
Mtr4 exosome RNA helicase
chr14_-_899170 0.21 ENSDART00000165211
ENSDART00000031992
rgs14a
regulator of G protein signaling 14a
chr15_+_34934568 0.21 ENSDART00000165210
zgc:66024
zgc:66024
chr12_+_23912074 0.21 ENSDART00000152864
svila
supervillin a
chr19_+_15441022 0.21 ENSDART00000098970
ENSDART00000140276
lin28a
lin-28 homolog A (C. elegans)
chr6_-_55399214 0.21 ENSDART00000168367
ctsa
cathepsin A
chr24_-_36238054 0.21 ENSDART00000155725
tmem241
transmembrane protein 241
chr20_-_20930926 0.21 ENSDART00000123909
btbd6b
BTB (POZ) domain containing 6b
chr21_-_36453594 0.21 ENSDART00000193176
cnot8
CCR4-NOT transcription complex, subunit 8
chr17_-_49412313 0.21 ENSDART00000152100
mthfd1b
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1b
chr25_-_2723902 0.21 ENSDART00000143721
ENSDART00000175224
adpgk
ADP-dependent glucokinase
chr13_+_11828516 0.21 ENSDART00000110141
sufu
suppressor of fused homolog (Drosophila)
chr5_-_9216758 0.21 ENSDART00000134896
ENSDART00000147000
lrp13
low-density lipoprotein receptor related-protein 13
chr18_-_30499489 0.21 ENSDART00000033746
gins2
GINS complex subunit 2
chr2_-_49854432 0.21 ENSDART00000180731
blvra
biliverdin reductase A
chr20_-_52902693 0.21 ENSDART00000166115
ENSDART00000161050
ctsbb
cathepsin Bb
chr21_+_15592426 0.21 ENSDART00000138207
smarcb1b
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1b
chr6_-_41028698 0.21 ENSDART00000134293
trub2
TruB pseudouridine (psi) synthase family member 2
chr12_+_28888975 0.20 ENSDART00000076362
phkg2
phosphorylase kinase, gamma 2 (testis)
chr19_-_82504 0.20 ENSDART00000027864
ENSDART00000160560
hnrnpr
heterogeneous nuclear ribonucleoprotein R
chr16_-_25368048 0.20 ENSDART00000132445
rbfa
ribosome binding factor A
chr23_-_25135046 0.20 ENSDART00000184844
ENSDART00000103989
idh3g
isocitrate dehydrogenase 3 (NAD+) gamma
chr2_-_49031303 0.20 ENSDART00000143471
cdc34b
cell division cycle 34 homolog (S. cerevisiae) b
chr13_-_31008275 0.20 ENSDART00000139394
wdfy4
WDFY family member 4
chr3_-_34136368 0.20 ENSDART00000136900
ENSDART00000186125
clpp
caseinolytic mitochondrial matrix peptidase proteolytic subunit
chr13_-_35808904 0.20 ENSDART00000171667
map3k4
mitogen-activated protein kinase kinase kinase 4
chr20_+_32523576 0.20 ENSDART00000147319
scml4
Scm polycomb group protein like 4
chr3_+_13848226 0.20 ENSDART00000184342
ilf3b
interleukin enhancer binding factor 3b
chr22_+_4488454 0.20 ENSDART00000170620
ctxn1
cortexin 1
chr13_+_49727333 0.20 ENSDART00000168799
ENSDART00000037559
ggps1
geranylgeranyl diphosphate synthase 1
chr22_-_38800173 0.20 ENSDART00000190725
si:ch211-262h13.3
si:ch211-262h13.3

Network of associatons between targets according to the STRING database.

First level regulatory network of si:dkey-43p13.5+uncx

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.9 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.3 0.8 GO:0072111 spinal cord anterior/posterior patterning(GO:0021512) cell proliferation involved in pronephros development(GO:0039015) cell proliferation involved in kidney development(GO:0072111)
0.2 0.8 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.2 0.5 GO:0000212 meiotic spindle organization(GO:0000212)
0.2 0.6 GO:0060283 negative regulation of oocyte development(GO:0060283)
0.1 0.5 GO:0035124 embryonic caudal fin morphogenesis(GO:0035124)
0.1 0.4 GO:0060631 regulation of meiosis I(GO:0060631)
0.1 0.1 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.1 0.3 GO:1904983 transmembrane glycine transport from cytosol to mitochondrion(GO:1904983)
0.1 0.4 GO:0061031 endodermal digestive tract morphogenesis(GO:0061031) Wnt signaling pathway involved in somitogenesis(GO:0090244) negative regulation of canonical Wnt signaling pathway involved in heart development(GO:1905067)
0.1 0.5 GO:0038107 nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145)
0.1 0.4 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.1 1.0 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 0.2 GO:0035477 regulation of angioblast cell migration involved in selective angioblast sprouting(GO:0035477)
0.1 0.3 GO:0070987 error-free translesion synthesis(GO:0070987)
0.1 0.8 GO:0006622 protein targeting to lysosome(GO:0006622)
0.1 0.6 GO:0044528 regulation of mitochondrial mRNA stability(GO:0044528)
0.1 0.3 GO:0010481 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.1 0.3 GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978) DNA damage response, signal transduction resulting in transcription(GO:0042772)
0.1 0.8 GO:0000002 mitochondrial genome maintenance(GO:0000002)
0.1 0.4 GO:0042795 snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.1 0.4 GO:1902292 cell cycle DNA replication initiation(GO:1902292) nuclear cell cycle DNA replication initiation(GO:1902315) mitotic DNA replication initiation(GO:1902975)
0.1 0.2 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553) negative regulation of lipid kinase activity(GO:0090219)
0.1 0.3 GO:0000455 enzyme-directed rRNA pseudouridine synthesis(GO:0000455)
0.1 0.2 GO:0046823 regulation of protein import into nucleus(GO:0042306) negative regulation of protein import into nucleus(GO:0042308) negative regulation of nucleocytoplasmic transport(GO:0046823) negative regulation of protein localization to nucleus(GO:1900181) regulation of protein import(GO:1904589) negative regulation of protein import(GO:1904590)
0.1 0.2 GO:0009211 pyrimidine deoxyribonucleoside triphosphate metabolic process(GO:0009211)
0.1 0.2 GO:0036306 embryonic heart tube elongation(GO:0036306)
0.1 0.3 GO:0046485 ether lipid metabolic process(GO:0046485)
0.0 0.1 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.0 0.1 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.2 GO:0000012 single strand break repair(GO:0000012)
0.0 0.3 GO:0032447 tRNA wobble position uridine thiolation(GO:0002143) protein urmylation(GO:0032447)
0.0 0.8 GO:0007339 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.0 0.3 GO:0048011 neurotrophin TRK receptor signaling pathway(GO:0048011)
0.0 0.2 GO:0010259 multicellular organism aging(GO:0010259)
0.0 0.3 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.2 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0 0.2 GO:0060049 regulation of protein glycosylation(GO:0060049)
0.0 0.2 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 0.6 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.3 GO:0033206 meiotic cytokinesis(GO:0033206) polar body extrusion after meiotic divisions(GO:0040038)
0.0 0.2 GO:0097355 protein localization to heterochromatin(GO:0097355)
0.0 0.3 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.1 GO:0045002 double-strand break repair via single-strand annealing(GO:0045002)
0.0 0.2 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0 0.1 GO:0006499 N-terminal protein myristoylation(GO:0006499) N-terminal peptidyl-glycine N-myristoylation(GO:0018008) protein myristoylation(GO:0018377)
0.0 0.1 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.0 0.1 GO:1903334 regulation of protein folding(GO:1903332) positive regulation of protein folding(GO:1903334) regulation of chaperone-mediated protein folding(GO:1903644) positive regulation of chaperone-mediated protein folding(GO:1903646)
0.0 0.6 GO:0032204 regulation of telomere maintenance(GO:0032204)
0.0 0.1 GO:0043461 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.0 1.4 GO:0018198 peptidyl-cysteine modification(GO:0018198)
0.0 0.2 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.3 GO:1903318 negative regulation of protein processing(GO:0010955) negative regulation of protein maturation(GO:1903318)
0.0 0.3 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 0.1 GO:0006660 phosphatidylserine catabolic process(GO:0006660) monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.0 0.2 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 0.1 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.0 0.5 GO:0006743 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone metabolic process(GO:1901661) quinone biosynthetic process(GO:1901663)
0.0 0.2 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.1 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.0 0.2 GO:0031048 chromatin silencing by small RNA(GO:0031048)
0.0 0.6 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.3 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.2 GO:0070285 pigment cell development(GO:0070285)
0.0 0.1 GO:0048532 anatomical structure arrangement(GO:0048532)
0.0 0.2 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.0 0.5 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.2 GO:0060976 coronary vasculature development(GO:0060976)
0.0 0.1 GO:0032776 DNA methylation on cytosine(GO:0032776)
0.0 0.1 GO:0015744 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422) malate transmembrane transport(GO:0071423)
0.0 0.1 GO:0035479 angioblast cell migration from lateral mesoderm to midline(GO:0035479)
0.0 0.3 GO:0061055 myotome development(GO:0061055)
0.0 0.7 GO:0051014 actin filament severing(GO:0051014)
0.0 0.4 GO:0006825 copper ion transport(GO:0006825)
0.0 0.2 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.1 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.0 0.2 GO:1901970 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0 0.1 GO:0048478 replication fork protection(GO:0048478)
0.0 0.4 GO:0045047 protein targeting to ER(GO:0045047) establishment of protein localization to endoplasmic reticulum(GO:0072599)
0.0 0.4 GO:0006047 UDP-N-acetylglucosamine metabolic process(GO:0006047)
0.0 0.2 GO:2001286 caveolin-mediated endocytosis(GO:0072584) negative regulation of clathrin-mediated endocytosis(GO:1900186) regulation of caveolin-mediated endocytosis(GO:2001286) negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.0 0.2 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.3 GO:2000401 regulation of lymphocyte migration(GO:2000401)
0.0 0.4 GO:0050796 regulation of insulin secretion(GO:0050796)
0.0 0.2 GO:0035677 posterior lateral line neuromast hair cell development(GO:0035677)
0.0 0.1 GO:0046083 adenine metabolic process(GO:0046083) adenine biosynthetic process(GO:0046084)
0.0 0.4 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.3 GO:1901534 positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.0 0.9 GO:1904029 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.0 0.3 GO:0035459 cargo loading into vesicle(GO:0035459)
0.0 0.1 GO:0070445 regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.0 0.1 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.0 0.4 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.0 0.3 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.1 GO:0090497 mesenchymal cell migration(GO:0090497)
0.0 0.1 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.2 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.0 0.2 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.0 GO:0000393 spliceosomal conformational changes to generate catalytic conformation(GO:0000393)
0.0 0.1 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.8 GO:0044744 protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744) single-organism nuclear import(GO:1902593)
0.0 0.1 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.0 0.1 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.0 0.2 GO:0035493 SNARE complex assembly(GO:0035493)
0.0 0.2 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.2 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.0 0.3 GO:0008354 germ cell migration(GO:0008354)
0.0 0.8 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 0.2 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 0.0 GO:0046379 renal water homeostasis(GO:0003091) renal water transport(GO:0003097) extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.0 0.1 GO:0051660 establishment of centrosome localization(GO:0051660)
0.0 0.2 GO:0001522 pseudouridine synthesis(GO:0001522)
0.0 0.0 GO:0021611 facial nerve formation(GO:0021611)
0.0 0.1 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.0 GO:0015919 peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.0 0.1 GO:0060347 ventricular trabecula myocardium morphogenesis(GO:0003222) trabecula formation(GO:0060343) heart trabecula formation(GO:0060347) skin epidermis development(GO:0098773)
0.0 0.0 GO:0036344 platelet formation(GO:0030220) platelet morphogenesis(GO:0036344)
0.0 0.2 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.3 GO:0060021 palate development(GO:0060021)
0.0 0.3 GO:0009214 cyclic nucleotide catabolic process(GO:0009214)
0.0 0.1 GO:0046386 deoxyribonucleotide catabolic process(GO:0009264) deoxyribose phosphate catabolic process(GO:0046386)
0.0 0.2 GO:0098943 neurotransmitter receptor transport, postsynaptic endosome to lysosome(GO:0098943)
0.0 0.1 GO:0090559 regulation of mitochondrial membrane permeability(GO:0046902) regulation of membrane permeability(GO:0090559)
0.0 0.2 GO:1990399 sensory epithelium regeneration(GO:0070654) epithelium regeneration(GO:1990399)
0.0 0.0 GO:0071918 urea transmembrane transport(GO:0071918)
0.0 0.1 GO:0015740 C4-dicarboxylate transport(GO:0015740)
0.0 0.3 GO:0006942 regulation of striated muscle contraction(GO:0006942)
0.0 0.2 GO:0021551 central nervous system morphogenesis(GO:0021551)
0.0 0.2 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.3 GO:0048264 determination of ventral identity(GO:0048264)
0.0 0.3 GO:0043038 amino acid activation(GO:0043038) tRNA aminoacylation(GO:0043039)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)
0.3 0.8 GO:0031166 integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
0.3 0.8 GO:0097189 apoptotic body(GO:0097189)
0.1 0.5 GO:0070724 BMP receptor complex(GO:0070724)
0.1 0.2 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.1 0.2 GO:1990072 TRAPPIII protein complex(GO:1990072)
0.1 0.4 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.1 0.2 GO:0035301 Hedgehog signaling complex(GO:0035301)
0.1 0.4 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 0.2 GO:0019185 snRNA-activating protein complex(GO:0019185)
0.1 1.8 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.2 GO:0098553 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.0 0.3 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.2 GO:0000811 GINS complex(GO:0000811)
0.0 0.1 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.0 0.1 GO:0005880 nuclear microtubule(GO:0005880)
0.0 0.3 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.1 GO:0072380 TRC complex(GO:0072380)
0.0 0.7 GO:0030667 secretory granule membrane(GO:0030667)
0.0 1.0 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.5 GO:0042555 MCM complex(GO:0042555)
0.0 0.1 GO:0070209 ASTRA complex(GO:0070209)
0.0 0.2 GO:0071818 BAT3 complex(GO:0071818)
0.0 0.3 GO:0070187 telosome(GO:0070187)
0.0 0.2 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.5 GO:0045180 basal cortex(GO:0045180)
0.0 0.1 GO:0035101 FACT complex(GO:0035101)
0.0 1.0 GO:0005657 replication fork(GO:0005657)
0.0 0.3 GO:0005682 U5 snRNP(GO:0005682)
0.0 2.5 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.1 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.3 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.2 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.2 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.6 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.2 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.1 GO:0000974 Prp19 complex(GO:0000974)
0.0 0.2 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.1 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.1 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.1 GO:0032021 NELF complex(GO:0032021)
0.0 0.4 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.2 GO:0071564 npBAF complex(GO:0071564)
0.0 0.1 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 0.4 GO:0005758 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 0.6 GO:0032580 Golgi cisterna membrane(GO:0032580)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.9 GO:0009374 biotin binding(GO:0009374)
0.2 0.8 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.1 0.4 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.1 0.4 GO:0008761 UDP-N-acetylglucosamine 2-epimerase activity(GO:0008761) N-acylmannosamine kinase activity(GO:0009384)
0.1 0.6 GO:0016531 copper chaperone activity(GO:0016531)
0.1 0.3 GO:0004113 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity(GO:0004113)
0.1 0.4 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
0.1 0.4 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.1 0.6 GO:0070698 type I activin receptor binding(GO:0070698)
0.1 1.4 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.1 0.2 GO:0019777 Atg12 transferase activity(GO:0019777)
0.1 0.9 GO:0008266 poly(U) RNA binding(GO:0008266)
0.1 0.2 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.1 0.2 GO:0016530 metallochaperone activity(GO:0016530)
0.1 0.2 GO:0070182 DNA polymerase binding(GO:0070182)
0.1 0.2 GO:0008488 gamma-glutamyl carboxylase activity(GO:0008488)
0.1 0.2 GO:0061656 SUMO conjugating enzyme activity(GO:0061656)
0.0 0.1 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0 0.8 GO:0032190 acrosin binding(GO:0032190)
0.0 0.1 GO:0001635 adrenomedullin receptor activity(GO:0001605) calcitonin gene-related peptide receptor activity(GO:0001635)
0.0 0.5 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.4 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 1.4 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.2 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.2 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.5 GO:0043028 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.0 0.2 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.2 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.2 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.3 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.7 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.3 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0 0.1 GO:0070336 flap-structured DNA binding(GO:0070336)
0.0 0.1 GO:0052905 tRNA (guanine(9)-N(1))-methyltransferase activity(GO:0052905)
0.0 0.1 GO:0004379 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379)
0.0 0.2 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.0 0.4 GO:0035250 UDP-galactosyltransferase activity(GO:0035250)
0.0 0.1 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.0 0.3 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.1 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.6 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.3 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.3 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.7 GO:0004659 prenyltransferase activity(GO:0004659)
0.0 0.4 GO:0031726 CCR1 chemokine receptor binding(GO:0031726) CCR4 chemokine receptor binding(GO:0031729)
0.0 0.3 GO:0017091 AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.3 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.0 0.2 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0 0.2 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0 0.2 GO:0008118 N-acetyllactosaminide alpha-2,3-sialyltransferase activity(GO:0008118)
0.0 0.1 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0 0.1 GO:0043621 protein self-association(GO:0043621)
0.0 0.1 GO:0015117 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131) malate transmembrane transporter activity(GO:0015140)
0.0 0.2 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.5 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 1.0 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.1 GO:0032052 bile acid binding(GO:0032052)
0.0 0.3 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.3 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.2 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.0 0.2 GO:0008506 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.0 0.2 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.8 GO:0005109 frizzled binding(GO:0005109)
0.0 0.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.2 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.0 0.1 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307)
0.0 0.1 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.1 GO:0000995 transcription factor activity, core RNA polymerase III binding(GO:0000995)
0.0 0.2 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.5 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.2 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.4 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.4 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.2 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.4 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.1 GO:0016742 hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.0 0.0 GO:0048030 disaccharide binding(GO:0048030)
0.0 0.2 GO:0031013 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.0 0.2 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.4 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.9 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.1 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 0.2 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.0 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.1 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.0 0.1 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.0 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.0 0.1 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 0.2 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.6 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.6 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.6 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 2.4 GO:0042802 identical protein binding(GO:0042802)
0.0 0.1 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.2 GO:0016409 palmitoyltransferase activity(GO:0016409)
0.0 0.1 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.4 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.6 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.8 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.3 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.4 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.2 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 0.2 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.3 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.2 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.1 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 2.1 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.2 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.1 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 0.2 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.2 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.5 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.4 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.2 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.6 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.3 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.6 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.5 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.2 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.4 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.2 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.2 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.0 0.2 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.7 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.3 REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.0 0.1 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.2 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.2 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.1 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.4 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.0 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.0 0.2 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.4 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.1 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.1 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.1 REACTOME BASE EXCISION REPAIR Genes involved in Base Excision Repair