ISMARA results: snai1a

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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for snai1a

Z-value: 2.91

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Transcription factors associated with snai1a

Gene Symbol	Gene ID	Gene Info
snai1a NCBI UniProt	ENSDARG00000056995	snail family zinc finger 1a

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
snai1a	dr11_v1_chr11_-_25257595_25257595	0.50	3.4e-02	Click!

Activity profile of snai1a motif

Sorted Z-values of snai1a motif

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Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr20_-_43743700 Show fit	14.41	ENSDART00000100620	si:dkeyp-50f7.2 NCBI UniProt Show fit	si:dkeyp-50f7.2
chr21_-_43666420 Show fit	10.92	ENSDART00000139008 ENSDART00000183996 ENSDART00000183395	si:dkey-229d11.3 NCBI UniProt Show fit si:dkey-229d11.5 NCBI UniProt Show fit	si:dkey-229d11.3 si:dkey-229d11.5
chr6_+_153146 Show fit	10.86	ENSDART00000097468	zglp1 NCBI UniProt Show fit	zinc finger, GATA-like protein 1
chr23_-_44574059 Show fit	10.24	ENSDART00000123007	si:ch73-160p18.3 NCBI UniProt Show fit	si:ch73-160p18.3
chr17_-_25331439 Show fit	10.16	ENSDART00000155422 ENSDART00000082324	zpcx NCBI UniProt Show fit	zona pellucida protein C
chr17_-_2596125 Show fit	9.13	ENSDART00000175740	zp3.2 NCBI UniProt Show fit	zona pellucida glycoprotein 3, tandem duplicate 2
chr1_+_24387659 Show fit	8.50	ENSDART00000130356	qdprb2 NCBI UniProt Show fit	quinoid dihydropteridine reductase b2
chr12_-_4301234 Show fit	8.33	ENSDART00000152377 ENSDART00000152521	ca15b NCBI UniProt Show fit	carbonic anhydrase XVb
chr9_+_8396755 Show fit	8.15	ENSDART00000043067	zgc:171776 NCBI UniProt Show fit	zgc:171776
chr10_+_19596214 Show fit	8.11	ENSDART00000183110	CABZ01059626.1 NCBI UniProt Show fit

Showing 1 to 10 of 200 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of snai1a

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
3.0	50.9	GO:2000344	binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.6	12.8	GO:0019368	fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.2	12.3	GO:0070098	chemokine-mediated signaling pathway(GO:0070098)
0.2	11.4	GO:0006487	protein N-linked glycosylation(GO:0006487)
0.2	10.5	GO:0031122	cytoplasmic microtubule organization(GO:0031122)
0.1	10.5	GO:0048545	response to steroid hormone(GO:0048545)
0.2	9.6	GO:0071880	adenylate cyclase-activating adrenergic receptor signaling pathway(GO:0071880)
0.5	9.0	GO:0008354	germ cell migration(GO:0008354)
0.1	8.9	GO:0006486	protein glycosylation(GO:0006486) macromolecule glycosylation(GO:0043413)
1.0	8.1	GO:0033206	meiotic cytokinesis(GO:0033206) polar body extrusion after meiotic divisions(GO:0040038)

Showing 1 to 10 of 542 entries

Gene overrepresentation in cellular component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	28.7	GO:0031012	extracellular matrix(GO:0031012)
0.0	27.4	GO:0005794	Golgi apparatus(GO:0005794)
0.1	17.9	GO:0043296	apical junction complex(GO:0043296)
0.0	13.1	GO:0005730	nucleolus(GO:0005730)
0.3	11.6	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.1	9.8	GO:0005769	early endosome(GO:0005769)
0.5	9.3	GO:0034993	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.4	8.2	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.1	7.8	GO:0000786	nucleosome(GO:0000786)
0.1	7.7	GO:0031228	integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)

Showing 1 to 10 of 210 entries

Gene overrepresentation in molecular function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.2	66.0	GO:0030246	carbohydrate binding(GO:0030246)
3.0	33.5	GO:0035804	structural constituent of egg coat(GO:0035804)
2.9	17.4	GO:0032190	acrosin binding(GO:0032190)
0.8	12.8	GO:0031729	CCR1 chemokine receptor binding(GO:0031726) CCR4 chemokine receptor binding(GO:0031729)
0.6	12.8	GO:0102336	fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0	12.4	GO:0003723	RNA binding(GO:0003723)
0.0	10.4	GO:0035091	phosphatidylinositol binding(GO:0035091)
1.3	10.3	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.4	9.7	GO:0004089	carbonate dehydratase activity(GO:0004089)
2.1	8.6	GO:0070404	6,7-dihydropteridine reductase activity(GO:0004155) NADH binding(GO:0070404)

Showing 1 to 10 of 382 entries

Gene overrepresentation in curated gene sets: canonical pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.2	8.1	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.3	6.8	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.1	6.8	PID P53 DOWNSTREAM PATHWAY	Direct p53 effectors
0.2	6.2	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.1	5.0	WNT SIGNALING	Genes related to Wnt-mediated signal transduction
0.1	3.4	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.5	3.1	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.2	3.1	PID ERBB4 PATHWAY	ErbB4 signaling events
0.1	3.1	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.1	3.1	PID E2F PATHWAY	E2F transcription factor network

Showing 1 to 10 of 68 entries

Gene overrepresentation in curated gene sets: REACTOME pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.2	8.1	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.7	7.2	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.2	7.0	REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN	Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.4	6.8	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.2	6.5	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.2	5.5	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.2	5.2	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.3	4.8	REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION	Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.7	4.6	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.2	4.6	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules

Showing 1 to 10 of 118 entries

Results for snai1a

Z-value: 2.91

Motif logo

Transcription factors associated with snai1a

Activity-expression correlation:

Activity profile of snai1a motif

Sorted Z-values of snai1a motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of snai1a

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: