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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for sox10

Z-value: 0.64

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Transcription factors associated with sox10

Gene Symbol Gene ID Gene Info
sox10
ENSDARG00000077467 SRY-box transcription factor 10

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
sox10dr11_v1_chr3_+_1492174_1492174-0.116.5e-01Click!

Activity profile of sox10 motif

Sorted Z-values of sox10 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr14_+_80685 1.01 ENSDART00000188443
stag3
stromal antigen 3
chr23_-_35483163 0.94 ENSDART00000138660
ENSDART00000113643
ENSDART00000189269
fbxo25
F-box protein 25
chr3_+_24197934 0.93 ENSDART00000055609
atf4b
activating transcription factor 4b
chr20_+_7584211 0.89 ENSDART00000132481
ENSDART00000127975
ENSDART00000144551
bloc1s2
biogenesis of lysosomal organelles complex-1, subunit 2
chr6_-_21091948 0.80 ENSDART00000057348
inha
inhibin, alpha
chr14_+_46313396 0.80 ENSDART00000047525
cryba1l1
crystallin, beta A1, like 1
chr10_+_44042033 0.79 ENSDART00000190006
ENSDART00000046172
cryba4
crystallin, beta A4
chr12_-_5418340 0.78 ENSDART00000028043
noc3l
NOC3-like DNA replication regulator
chr20_-_14665002 0.76 ENSDART00000152816
scrn2
secernin 2
chr17_-_6599484 0.75 ENSDART00000156927
ANKRD66
si:ch211-189e2.2
chr4_+_15819728 0.75 ENSDART00000101613
lrguk
leucine-rich repeats and guanylate kinase domain containing
chr20_-_54014539 0.74 ENSDART00000060466
si:dkey-241l7.6
si:dkey-241l7.6
chr14_+_46313135 0.74 ENSDART00000172902
cryba1l1
crystallin, beta A1, like 1
chr14_-_28567845 0.71 ENSDART00000126095
insb
preproinsulin b
chr16_+_9762261 0.70 ENSDART00000020654
psmd4b
proteasome 26S subunit, non-ATPase 4b
chr21_-_32301109 0.69 ENSDART00000139890
clk4b
CDC-like kinase 4b
chr3_+_15505275 0.69 ENSDART00000141714
nupr1
nuclear protein 1
chr16_-_2650341 0.66 ENSDART00000128169
ENSDART00000155432
ENSDART00000103722
lyplal1
lysophospholipase-like 1
chr24_+_11083146 0.66 ENSDART00000009473
zfand1
zinc finger, AN1-type domain 1
chr8_+_2575993 0.65 ENSDART00000112914
si:ch211-51h9.7
si:ch211-51h9.7
chr18_+_20838786 0.65 ENSDART00000138692
ttc23
tetratricopeptide repeat domain 23
chr3_-_41535647 0.65 ENSDART00000153723
ENSDART00000154198
si:ch211-222n22.1
si:ch211-222n22.1
chr9_-_18911608 0.64 ENSDART00000138785
si:dkey-239h2.3
si:dkey-239h2.3
chr23_-_31506854 0.63 ENSDART00000131352
ENSDART00000138625
ENSDART00000133002
eya4
EYA transcriptional coactivator and phosphatase 4
chr15_-_39955785 0.61 ENSDART00000154556
msh5
mutS homolog 5
chr5_+_67662430 0.59 ENSDART00000137700
ENSDART00000142586
si:dkey-70b23.2
si:dkey-70b23.2
chr4_+_72742212 0.59 ENSDART00000171021
rab3ip
RAB3A interacting protein (rabin3)
chr11_+_13528437 0.58 ENSDART00000011362
arrdc2
arrestin domain containing 2
chr8_-_13315304 0.58 ENSDART00000142596
kcnn1b
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1b
chr11_-_11471857 0.57 ENSDART00000030103
krt94
keratin 94
chr8_-_13315567 0.56 ENSDART00000132685
ENSDART00000168635
kcnn1b
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1b
chr25_+_35058088 0.56 ENSDART00000156838
zgc:112234
zgc:112234
chr11_+_26604224 0.55 ENSDART00000030453
ENSDART00000168895
ENSDART00000159505
dynlrb1
dynein, light chain, roadblock-type 1
chr15_+_44053244 0.54 ENSDART00000059550
lrrc51
leucine rich repeat containing 51
chr7_-_35126374 0.53 ENSDART00000141211
hsd11b2
hydroxysteroid (11-beta) dehydrogenase 2
chr21_+_19347655 0.52 ENSDART00000093155
hpse
heparanase
chr16_-_26731928 0.52 ENSDART00000135860
rnf41l
ring finger protein 41, like
chr21_-_25756119 0.51 ENSDART00000002341
cldnc
claudin c
chr3_+_24458204 0.51 ENSDART00000155028
ENSDART00000153551
cbx6b
chromobox homolog 6b
chr23_-_30727596 0.51 ENSDART00000060193
thap3
THAP domain containing, apoptosis associated protein 3
chr5_+_43807003 0.50 ENSDART00000097625
zgc:158640
zgc:158640
chr5_-_6377865 0.50 ENSDART00000031775
zgc:73226
zgc:73226
chr3_-_16250527 0.50 ENSDART00000146699
ENSDART00000141181
bckdhbl
branched chain keto acid dehydrogenase E1, beta polypeptide, like
chr5_-_71705191 0.49 ENSDART00000187767
ak1
adenylate kinase 1
chr7_+_22688781 0.48 ENSDART00000173509
ugt5g1
UDP glucuronosyltransferase 5 family, polypeptide G1
chr22_-_15587360 0.48 ENSDART00000142717
ENSDART00000138978
tpm4a
tropomyosin 4a
chr12_-_30841679 0.48 ENSDART00000105594
crygmx
crystallin, gamma MX
chr14_-_33348221 0.47 ENSDART00000187749
rpl39
ribosomal protein L39
chr4_-_193762 0.47 ENSDART00000169667
ptpro
protein tyrosine phosphatase, receptor type, O
chr2_+_3472832 0.47 ENSDART00000115278
cx47.1
connexin 47.1
chr21_+_7131970 0.47 ENSDART00000161921
zgc:113019
zgc:113019
chr12_-_42368296 0.47 ENSDART00000171075
zgc:111868
zgc:111868
chr24_+_5840258 0.46 ENSDART00000087034
trpc1
transient receptor potential cation channel, subfamily C, member 1
chr23_+_36340520 0.46 ENSDART00000011201
copz1
coatomer protein complex, subunit zeta 1
chr25_+_20716176 0.46 ENSDART00000073651
ergic2
ERGIC and golgi 2
chr5_+_69868911 0.46 ENSDART00000014649
ENSDART00000188215
ENSDART00000167385
ugt2a5
UDP glucuronosyltransferase 2 family, polypeptide A5
chr5_-_51148298 0.46 ENSDART00000042420
ccdc180
coiled-coil domain containing 180
chr5_+_9134187 0.45 ENSDART00000132240
pimr123
Pim proto-oncogene, serine/threonine kinase, related 123
chr15_-_108414 0.45 ENSDART00000170044
apoa1b
apolipoprotein A-Ib
chr20_+_39457598 0.45 ENSDART00000140931
ENSDART00000156176
pimr128
Pim proto-oncogene, serine/threonine kinase, related 128
chr5_-_41645058 0.45 ENSDART00000051092
riok2
RIO kinase 2 (yeast)
chr16_+_40560622 0.45 ENSDART00000038294
tp53inp1
tumor protein p53 inducible nuclear protein 1
chr9_-_29497916 0.45 ENSDART00000060246
dnajc3a
DnaJ (Hsp40) homolog, subfamily C, member 3a
chr6_-_6993046 0.45 ENSDART00000053304
si:ch211-114n24.6
si:ch211-114n24.6
chr13_-_1151410 0.45 ENSDART00000007231
psmb1
proteasome subunit beta 1
chr17_-_122680 0.44 ENSDART00000066430
actc1b
actin, alpha, cardiac muscle 1b
chr19_+_18903533 0.44 ENSDART00000157523
ENSDART00000166562
slc39a7
solute carrier family 39 (zinc transporter), member 7
chr1_+_41849152 0.44 ENSDART00000053685
smox
spermine oxidase
chr23_-_30787932 0.44 ENSDART00000135771
myt1a
myelin transcription factor 1a
chr11_+_24820542 0.43 ENSDART00000135443
kdm5ba
lysine (K)-specific demethylase 5Ba
chr23_+_22658700 0.43 ENSDART00000192248
eno1a
enolase 1a, (alpha)
chr19_+_63567 0.42 ENSDART00000165657
ENSDART00000165183
zhx2b
zinc fingers and homeoboxes 2b
chr8_-_14067517 0.42 ENSDART00000140948
dedd
death effector domain containing
chr12_-_34035364 0.42 ENSDART00000087065
timp2a
TIMP metallopeptidase inhibitor 2a
chr6_-_51101834 0.42 ENSDART00000092493
ptprt
protein tyrosine phosphatase, receptor type, t
chr23_-_14830627 0.42 ENSDART00000134659
sla2
Src-like-adaptor 2
chr19_+_15521997 0.41 ENSDART00000003164
ppp1r8a
protein phosphatase 1, regulatory subunit 8a
chr12_-_15567104 0.41 ENSDART00000053003
hexim1
hexamethylene bis-acetamide inducible 1
chr5_-_64883082 0.40 ENSDART00000064983
ENSDART00000139066
krt1-c5
keratin, type 1, gene c5
chr24_+_18714212 0.39 ENSDART00000171181
cspp1a
centrosome and spindle pole associated protein 1a
chr19_+_26714949 0.39 ENSDART00000188540
zgc:100906
zgc:100906
chr25_+_16689633 0.39 ENSDART00000073416
ada2a
adenosine deaminase 2a
chr15_+_28368644 0.39 ENSDART00000168453
slc43a2a
solute carrier family 43 (amino acid system L transporter), member 2a
chr7_+_24814866 0.39 ENSDART00000173581
si:ch211-226l4.6
si:ch211-226l4.6
chr21_-_18972206 0.39 ENSDART00000146743
pimr72
Pim proto-oncogene, serine/threonine kinase, related 72
chr14_-_33360344 0.39 ENSDART00000181291
pimr117
Pim proto-oncogene, serine/threonine kinase, related 117
chr23_+_12545114 0.38 ENSDART00000105283
ENSDART00000166990
si:zfos-452g4.1
si:zfos-452g4.1
chr24_-_24114217 0.38 ENSDART00000160578
zgc:112982
zgc:112982
chr14_-_4170654 0.37 ENSDART00000188347
si:dkey-185e18.7
si:dkey-185e18.7
chr22_+_1911269 0.37 ENSDART00000164158
ENSDART00000168205
znf1156
zinc finger protein 1156
chr25_+_14400704 0.37 ENSDART00000067235
ciapin1
cytokine induced apoptosis inhibitor 1
chr15_-_16183583 0.37 ENSDART00000062335
glod4
glyoxalase domain containing 4
chr18_-_4957022 0.36 ENSDART00000101686
zbbx
zinc finger, B-box domain containing
chr8_-_50147948 0.36 ENSDART00000149010
hp
haptoglobin
chr6_+_33885828 0.35 ENSDART00000179994
gpbp1l1
GC-rich promoter binding protein 1-like 1
chr7_-_6459481 0.35 ENSDART00000173158
zgc:112234
zgc:112234
chr9_-_24985511 0.35 ENSDART00000141957
dnah7
dynein, axonemal, heavy chain 7
chr20_+_25586099 0.35 ENSDART00000063122
ENSDART00000134047
cyp2p10
cytochrome P450, family 2, subfamily P, polypeptide 10
chr5_+_9112291 0.35 ENSDART00000135177
AL845369.1

chr3_-_53114299 0.35 ENSDART00000109390
AL954361.1

chr2_-_30912922 0.34 ENSDART00000141669
myl12.2
myosin, light chain 12, genome duplicate 2
chr2_-_30912307 0.34 ENSDART00000188653
myl12.2
myosin, light chain 12, genome duplicate 2
chr21_-_35853245 0.34 ENSDART00000172245
sgcd
sarcoglycan, delta (dystrophin-associated glycoprotein)
chr3_-_18030938 0.34 ENSDART00000013540
si:ch73-141c7.1
si:ch73-141c7.1
chr11_+_35364445 0.33 ENSDART00000125766
camkvb
CaM kinase-like vesicle-associated b
chr7_-_22981796 0.33 ENSDART00000167565
si:dkey-171c9.3
si:dkey-171c9.3
chr15_-_28200049 0.33 ENSDART00000004200
sarm1
sterile alpha and TIR motif containing 1
chr15_+_3825117 0.33 ENSDART00000183315
CABZ01061591.1

chr7_+_49664174 0.33 ENSDART00000137059
ENSDART00000131210
rassf7b
Ras association (RalGDS/AF-6) domain family (N-terminal) member 7b
chr16_+_53125918 0.33 ENSDART00000102170
CABZ01053976.1

chr1_-_10847753 0.33 ENSDART00000141052
dmd
dystrophin
chr10_+_16501699 0.32 ENSDART00000121864
slc27a6
solute carrier family 27 (fatty acid transporter), member 6
chr12_-_36045283 0.32 ENSDART00000160646
gprc5c
G protein-coupled receptor, class C, group 5, member C
chr14_+_9287683 0.31 ENSDART00000122485
msnb
moesin b
chr4_+_17280868 0.31 ENSDART00000145349
bcat1
branched chain amino-acid transaminase 1, cytosolic
chr22_-_10570749 0.31 ENSDART00000140736
si:dkey-42i9.6
si:dkey-42i9.6
chr21_-_28920245 0.31 ENSDART00000132884
cxxc5a
CXXC finger protein 5a
chr2_+_19522082 0.31 ENSDART00000146098
pimr49
Pim proto-oncogene, serine/threonine kinase, related 49
chr12_+_35654749 0.31 ENSDART00000169889
ENSDART00000167873
baiap2b
BAI1-associated protein 2b
chr2_+_13721888 0.31 ENSDART00000089618
zbtb41
zinc finger and BTB domain containing 41
chr2_-_42960353 0.31 ENSDART00000098303
oc90
otoconin 90
chr2_-_32768951 0.31 ENSDART00000004712
bfsp2
beaded filament structural protein 2, phakinin
chr7_+_73819078 0.31 ENSDART00000169756
FP236812.1
Histone H2B 1/2
chr21_-_2310064 0.30 ENSDART00000169520
si:ch211-241b2.1
si:ch211-241b2.1
chr2_-_45510699 0.30 ENSDART00000024034
ENSDART00000145634
gpsm2
G protein signaling modulator 2
chr19_-_3876877 0.30 ENSDART00000163711
thrap3b
thyroid hormone receptor associated protein 3b
chr20_+_18225329 0.30 ENSDART00000144172
kctd1
potassium channel tetramerization domain containing 1
chr24_-_2843107 0.29 ENSDART00000165290
cyb5a
cytochrome b5 type A (microsomal)
chr20_+_25568694 0.29 ENSDART00000063107
ENSDART00000063128
cyp2p7
cytochrome P450, family 2, subfamily P, polypeptide 7
chr11_-_41220794 0.29 ENSDART00000192895
mrps16
mitochondrial ribosomal protein S16
chr24_-_26369185 0.29 ENSDART00000080039
lrrc31
leucine rich repeat containing 31
chr12_-_35883814 0.29 ENSDART00000177986
ENSDART00000129888
cep131
centrosomal protein 131
chr16_-_45917322 0.29 ENSDART00000060822
afp4
antifreeze protein type IV
chr17_-_20236228 0.29 ENSDART00000136490
ENSDART00000029380
bnip4
BCL2 interacting protein 4
chr25_-_12788370 0.28 ENSDART00000158551
slc7a5
solute carrier family 7 (amino acid transporter light chain, L system), member 5
chr1_+_17376922 0.28 ENSDART00000145068
fat1a
FAT atypical cadherin 1a
chr1_-_19845378 0.28 ENSDART00000139314
ENSDART00000132958
ENSDART00000147502
grhprb
glyoxylate reductase/hydroxypyruvate reductase b
chr2_+_19633493 0.28 ENSDART00000147989
pimr54
Pim proto-oncogene, serine/threonine kinase, related 54
chr6_-_9922266 0.28 ENSDART00000151549
pimr73
Pim proto-oncogene, serine/threonine kinase, related 73
chr4_-_76154252 0.28 ENSDART00000161269
BX957252.1

chr3_-_24458281 0.28 ENSDART00000153993
baiap2l2a
BAI1-associated protein 2-like 2a
chr6_-_7020162 0.28 ENSDART00000148982
bin1b
bridging integrator 1b
chr22_-_16180849 0.28 ENSDART00000090390
vcam1b
vascular cell adhesion molecule 1b
chr8_+_42998944 0.28 ENSDART00000048819
rassf2a
Ras association (RalGDS/AF-6) domain family member 2a
chr4_-_11403811 0.27 ENSDART00000067272
ENSDART00000140018
pimr173
Pim proto-oncogene, serine/threonine kinase, related 173
chr13_+_28854438 0.27 ENSDART00000193407
ENSDART00000189554
CU639469.1

chr6_+_45932276 0.27 ENSDART00000103491
rbp7b
retinol binding protein 7b, cellular
chr17_-_24564674 0.27 ENSDART00000105435
ENSDART00000135086
abch1
ATP-binding cassette, sub-family H, member 1
chr3_-_31069776 0.27 ENSDART00000167462
elob
elongin B
chr22_+_14051894 0.27 ENSDART00000142548
aox6
aldehyde oxidase 6
chr9_-_27857265 0.26 ENSDART00000177513
ENSDART00000143166
ENSDART00000115313
si:rp71-45g20.4
si:rp71-45g20.4
chr9_+_38737924 0.26 ENSDART00000147652
kansl1l
KAT8 regulatory NSL complex subunit 1-like
chr6_+_14980761 0.26 ENSDART00000087782
mrps9
mitochondrial ribosomal protein S9
chr11_+_6882362 0.26 ENSDART00000144181
klhl26
kelch-like family member 26
chr22_+_29067388 0.26 ENSDART00000133673
pimr100
Pim proto-oncogene, serine/threonine kinase, related 100
chr25_-_13490744 0.25 ENSDART00000056721
ldhd
lactate dehydrogenase D
chr2_+_13722116 0.25 ENSDART00000155015
zbtb41
zinc finger and BTB domain containing 41
chr11_+_6882049 0.25 ENSDART00000075998
klhl26
kelch-like family member 26
chr12_-_7655322 0.25 ENSDART00000181162
ank3b
ankyrin 3b
chr2_-_25140022 0.24 ENSDART00000134543
nceh1a
neutral cholesterol ester hydrolase 1a
chr23_+_36144487 0.24 ENSDART00000082473
hoxc3a
homeobox C3a
chr10_-_42131408 0.24 ENSDART00000076693
stambpa
STAM binding protein a
chr7_-_60096318 0.24 ENSDART00000189125
BX511067.1

chr6_-_23931442 0.24 ENSDART00000160547
sec16b
SEC16 homolog B, endoplasmic reticulum export factor
chr25_+_35132090 0.24 ENSDART00000154377
si:dkey-261m9.6
si:dkey-261m9.6
chr5_-_30984010 0.24 ENSDART00000182367
spns3
spinster homolog 3 (Drosophila)
chr21_-_17603182 0.24 ENSDART00000020048
ENSDART00000177270
gsna
gelsolin a
chr17_+_26208630 0.23 ENSDART00000087084
grid1a
glutamate receptor, ionotropic, delta 1a
chr9_+_27411502 0.23 ENSDART00000143994
si:dkey-193n17.9
si:dkey-193n17.9
chr14_-_26400501 0.23 ENSDART00000054189
pimr212
Pim proto-oncogene, serine/threonine kinase, related 212
chr11_+_2600612 0.23 ENSDART00000173442
dnajc14
DnaJ (Hsp40) homolog, subfamily C, member 14
chr8_-_16697912 0.23 ENSDART00000076542
rpe65b
retinal pigment epithelium-specific protein 65b
chr21_-_13972745 0.23 ENSDART00000143874
akna
AT-hook transcription factor
chr16_-_32233463 0.23 ENSDART00000102016
calhm6
calcium homeostasis modulator family member 6
chr16_-_50203058 0.23 ENSDART00000154570
vsig10l
V-set and immunoglobulin domain containing 10 like
chr3_+_3545825 0.23 ENSDART00000109060
CR589947.1

chr2_-_19576640 0.23 ENSDART00000141021
pimr51
Pim proto-oncogene, serine/threonine kinase, related 51
chr3_-_58226583 0.22 ENSDART00000187429
im:6904045
im:6904045
chr7_-_34329527 0.22 ENSDART00000173454
madd
MAP-kinase activating death domain
chr18_-_14836862 0.22 ENSDART00000124843
mtss1la
metastasis suppressor 1-like a
chr2_-_45510223 0.22 ENSDART00000113058
gpsm2
G protein signaling modulator 2
chr5_+_58397646 0.22 ENSDART00000180759
HEPACAM
hepatic and glial cell adhesion molecule
chr1_-_51474974 0.22 ENSDART00000152719
spred2a
sprouty-related, EVH1 domain containing 2a
chr13_+_36958086 0.21 ENSDART00000024386
frmd6
FERM domain containing 6
chr7_+_20019125 0.21 ENSDART00000186391
bcl6b
B-cell CLL/lymphoma 6, member B
chr11_-_7147540 0.21 ENSDART00000143942
bmp7a
bone morphogenetic protein 7a
chr4_-_71110826 0.21 ENSDART00000167431
si:dkeyp-80d11.1
si:dkeyp-80d11.1
chr20_-_284865 0.21 ENSDART00000104806
wisp3
WNT1 inducible signaling pathway protein 3
chr5_+_57658898 0.21 ENSDART00000074268
ENSDART00000124568
zgc:153929
zgc:153929
chr5_+_36870737 0.20 ENSDART00000145182
slc8a2a
solute carrier family 8 (sodium/calcium exchanger), member 2a
chr18_-_37241080 0.20 ENSDART00000126421
ENSDART00000078064
six9
SIX homeobox 9
chr11_+_583142 0.20 ENSDART00000168157
mkrn2os.2
MKRN2 opposite strand, tandem duplicate 2
chr23_-_21471022 0.20 ENSDART00000104206
her4.2
hairy-related 4, tandem duplicate 2
chr12_+_26706745 0.20 ENSDART00000141401
arhgap12b
Rho GTPase activating protein 12b
chr11_-_3381343 0.20 ENSDART00000002545
mcrs1
microspherule protein 1
chr2_+_35595454 0.20 ENSDART00000098734
cacybp
calcyclin binding protein
chr3_+_30500968 0.20 ENSDART00000103447
si:dkey-13n23.3
si:dkey-13n23.3
chr22_+_1028724 0.20 ENSDART00000149625
si:ch73-352p18.4
si:ch73-352p18.4
chr22_+_1462177 0.20 ENSDART00000164685
si:dkeyp-53d3.5
si:dkeyp-53d3.5
chr9_+_35876927 0.20 ENSDART00000138834
mab21l3
mab-21-like 3

Network of associatons between targets according to the STRING database.

First level regulatory network of sox10

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0019364 pyridine nucleotide catabolic process(GO:0019364) NAD catabolic process(GO:0019677) pyridine-containing compound catabolic process(GO:0072526)
0.1 0.9 GO:1902038 positive regulation of hematopoietic stem cell differentiation(GO:1902038)
0.1 0.5 GO:0010873 regulation of cholesterol esterification(GO:0010872) positive regulation of cholesterol esterification(GO:0010873)
0.1 0.8 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.1 0.3 GO:0006089 lactate metabolic process(GO:0006089)
0.1 0.3 GO:0009098 leucine biosynthetic process(GO:0009098)
0.1 0.4 GO:0046103 adenosine catabolic process(GO:0006154) inosine metabolic process(GO:0046102) inosine biosynthetic process(GO:0046103)
0.1 0.5 GO:0034650 cortisol metabolic process(GO:0034650)
0.1 0.4 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.1 0.6 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.1 0.5 GO:0009136 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180)
0.1 0.4 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.1 0.6 GO:2001240 histone dephosphorylation(GO:0016576) negative regulation of signal transduction in absence of ligand(GO:1901099) regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001239) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.1 0.2 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.1 0.4 GO:1904030 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.1 0.2 GO:1901827 tetraterpenoid metabolic process(GO:0016108) tetraterpenoid biosynthetic process(GO:0016109) carotenoid metabolic process(GO:0016116) carotenoid biosynthetic process(GO:0016117) xanthophyll metabolic process(GO:0016122) xanthophyll biosynthetic process(GO:0016123) zeaxanthin metabolic process(GO:1901825) zeaxanthin biosynthetic process(GO:1901827)
0.1 0.6 GO:0000710 meiotic mismatch repair(GO:0000710)
0.1 0.7 GO:0007525 somatic muscle development(GO:0007525)
0.1 0.4 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.1 0.7 GO:0098734 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.0 0.2 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.7 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.1 GO:0021530 spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.0 0.3 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 0.2 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.0 0.1 GO:0046125 deoxyribonucleoside metabolic process(GO:0009120) thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.0 0.1 GO:0072196 proximal/distal pattern formation involved in nephron development(GO:0072047) proximal/distal pattern formation involved in pronephric nephron development(GO:0072196)
0.0 0.2 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.3 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.0 0.1 GO:0061178 insulin secretion involved in cellular response to glucose stimulus(GO:0035773) regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.0 0.2 GO:0010799 regulation of peptidyl-threonine phosphorylation(GO:0010799) negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.0 0.1 GO:0015677 copper ion import(GO:0015677)
0.0 0.2 GO:0010456 cell proliferation in dorsal spinal cord(GO:0010456)
0.0 0.1 GO:0060155 secretory granule organization(GO:0033363) platelet dense granule organization(GO:0060155)
0.0 0.1 GO:0003322 pancreatic A cell development(GO:0003322)
0.0 0.2 GO:1902765 L-arginine import(GO:0043091) amino acid import across plasma membrane(GO:0089718) arginine import(GO:0090467) L-arginine import across plasma membrane(GO:0097638) L-arginine transport(GO:1902023) L-arginine import into cell(GO:1902765) amino acid import into cell(GO:1902837) L-arginine transmembrane transport(GO:1903400) arginine transmembrane transport(GO:1903826)
0.0 0.1 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.2 GO:1902047 polyamine transport(GO:0015846) polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267) positive regulation of polyamine transmembrane transport(GO:1902269)
0.0 3.4 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.5 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)
0.0 0.3 GO:0021703 locus ceruleus development(GO:0021703)
0.0 0.1 GO:0061303 cornea development in camera-type eye(GO:0061303)
0.0 0.1 GO:0003151 outflow tract morphogenesis(GO:0003151)
0.0 0.1 GO:0045887 regulation of synaptic growth at neuromuscular junction(GO:0008582) axon regeneration at neuromuscular junction(GO:0014814) positive regulation of synaptic growth at neuromuscular junction(GO:0045887)
0.0 0.8 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.4 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.4 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.2 GO:0001958 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 0.2 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.0 0.2 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.0 0.1 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.1 GO:0055016 hypochord development(GO:0055016)
0.0 0.1 GO:0033278 cell proliferation in midbrain(GO:0033278)
0.0 0.6 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 0.5 GO:0042073 intraciliary transport(GO:0042073)
0.0 1.0 GO:0017144 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.0 1.0 GO:0007062 sister chromatid cohesion(GO:0007062)
0.0 0.1 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.0 0.1 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 0.8 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 0.4 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.1 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.0 0.2 GO:0031295 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0 0.6 GO:0021587 cerebellum morphogenesis(GO:0021587)
0.0 0.2 GO:0098719 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.2 GO:0006842 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.0 0.6 GO:0051904 melanosome transport(GO:0032402) pigment granule transport(GO:0051904)
0.0 0.4 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.1 GO:0070285 pigment cell development(GO:0070285)
0.0 0.2 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.0 0.4 GO:0035308 negative regulation of dephosphorylation(GO:0035305) negative regulation of protein dephosphorylation(GO:0035308)
0.0 0.1 GO:0000012 single strand break repair(GO:0000012)
0.0 0.1 GO:0003261 cardiac muscle progenitor cell migration to the midline involved in heart field formation(GO:0003261)
0.0 0.2 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.1 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.0 0.1 GO:0060612 adipose tissue development(GO:0060612)
0.0 0.1 GO:0046471 cardiolipin metabolic process(GO:0032048) phosphatidylglycerol metabolic process(GO:0046471)
0.0 0.5 GO:0015908 fatty acid transport(GO:0015908)
0.0 0.1 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.3 GO:0071910 determination of liver left/right asymmetry(GO:0071910)
0.0 0.4 GO:0015807 L-amino acid transport(GO:0015807)
0.0 0.1 GO:0051703 social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.0 0.1 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.0 0.2 GO:0097178 ruffle assembly(GO:0097178)
0.0 0.3 GO:0060030 dorsal convergence(GO:0060030)
0.0 0.1 GO:0030431 sleep(GO:0030431)
0.0 0.2 GO:1990089 response to nerve growth factor(GO:1990089) cellular response to nerve growth factor stimulus(GO:1990090)
0.0 0.5 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.2 GO:0043407 negative regulation of MAP kinase activity(GO:0043407)
0.0 3.7 GO:0046777 protein autophosphorylation(GO:0046777)
0.0 0.2 GO:0098659 inorganic cation import into cell(GO:0098659) calcium ion import across plasma membrane(GO:0098703) inorganic ion import into cell(GO:0099587) calcium ion import into cell(GO:1990035)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0070319 Golgi to plasma membrane transport vesicle(GO:0070319)
0.1 0.3 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.1 0.9 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 0.9 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.1 0.2 GO:0034709 methylosome(GO:0034709)
0.1 0.4 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 0.3 GO:0070062 extracellular exosome(GO:0070062)
0.0 0.7 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.3 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.3 GO:0030891 VCB complex(GO:0030891)
0.0 1.0 GO:0008278 cohesin complex(GO:0008278)
0.0 0.5 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.6 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.5 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.5 GO:0042627 chylomicron(GO:0042627)
0.0 0.5 GO:0044545 NSL complex(GO:0044545)
0.0 0.1 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.0 0.5 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.4 GO:0005869 dynactin complex(GO:0005869)
0.0 0.3 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.5 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.1 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.0 0.3 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.2 GO:0031526 brush border membrane(GO:0031526)
0.0 0.5 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.1 GO:0097268 cytoophidium(GO:0097268)
0.0 0.4 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.1 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024) nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.0 0.2 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.7 GO:0016592 mediator complex(GO:0016592)
0.0 0.1 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.2 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.1 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0070004 cysteine-type exopeptidase activity(GO:0070004)
0.1 0.7 GO:0004385 guanylate kinase activity(GO:0004385)
0.1 1.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.1 0.3 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.1 0.4 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.1 0.5 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.1 0.3 GO:0004031 aldehyde oxidase activity(GO:0004031) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.1 0.3 GO:0052655 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.1 0.3 GO:0046592 polyamine oxidase activity(GO:0046592)
0.1 0.2 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.1 0.2 GO:0052885 retinol isomerase activity(GO:0050251) all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity(GO:0052885)
0.1 0.9 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 0.4 GO:0001948 glycoprotein binding(GO:0001948) proteoglycan binding(GO:0043394)
0.1 0.4 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 0.4 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 0.2 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.3 GO:0048156 tau protein binding(GO:0048156)
0.0 0.3 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.4 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.4 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.0 0.2 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.0 0.4 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.2 GO:0070052 collagen V binding(GO:0070052)
0.0 0.5 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.2 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.0 0.3 GO:0048039 ubiquinone binding(GO:0048039)
0.0 0.3 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.6 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 2.8 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.2 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.0 0.1 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.0 0.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.2 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.0 0.1 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.7 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.3 GO:0004457 lactate dehydrogenase activity(GO:0004457)
0.0 0.1 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.1 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0 0.5 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.1 GO:0060182 apelin receptor activity(GO:0060182)
0.0 0.1 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.0 0.2 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.1 GO:0005252 open rectifier potassium channel activity(GO:0005252)
0.0 0.2 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.0 0.1 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.1 GO:0017113 uracil binding(GO:0002058) pyrimidine nucleobase binding(GO:0002061) dihydropyrimidine dehydrogenase (NADP+) activity(GO:0017113)
0.0 0.1 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.0 0.5 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor(GO:0033764)
0.0 0.4 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.1 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.0 0.1 GO:0099602 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0 0.1 GO:0003994 aconitate hydratase activity(GO:0003994)
0.0 0.3 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.2 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.2 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.5 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.1 GO:0070573 metallodipeptidase activity(GO:0070573)
0.0 0.2 GO:0015250 water channel activity(GO:0015250)
0.0 0.1 GO:0003883 CTP synthase activity(GO:0003883)
0.0 1.0 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 1.0 GO:0009055 electron carrier activity(GO:0009055)
0.0 0.1 GO:0000254 C-4 methylsterol oxidase activity(GO:0000254)
0.0 0.6 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.1 GO:0048407 platelet-derived growth factor-activated receptor activity(GO:0005017) platelet-derived growth factor binding(GO:0048407)
0.0 0.1 GO:0098634 C-X3-C chemokine binding(GO:0019960) protein binding involved in cell-matrix adhesion(GO:0098634) collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 0.5 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.2 GO:0005451 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0 0.4 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.4 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.2 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 1.0 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0 0.2 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.4 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
0.0 0.0 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0 0.2 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.1 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.0 0.3 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 0.1 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.1 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.4 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 0.1 GO:0004962 endothelin receptor activity(GO:0004962)
0.0 0.3 GO:0051018 protein kinase A binding(GO:0051018)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.1 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.5 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.6 PID TGFBR PATHWAY TGF-beta receptor signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.5 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.4 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 1.0 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.4 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.5 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.2 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.4 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.1 REACTOME FGFR2C LIGAND BINDING AND ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.0 0.3 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.6 REACTOME MEIOSIS Genes involved in Meiosis
0.0 0.2 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.3 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.1 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS Genes involved in Synthesis of bile acids and bile salts
0.0 0.1 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.4 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)