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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for sox12

Z-value: 1.17

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Transcription factors associated with sox12

Gene Symbol Gene ID Gene Info
sox12
ENSDARG00000025847 SRY-box transcription factor 12

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
sox12dr11_v1_chr11_-_24191928_24191928-0.831.8e-05Click!

Activity profile of sox12 motif

Sorted Z-values of sox12 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr10_-_32660716 4.19 ENSDART00000063544
ENSDART00000141013
atg101
autophagy related 101
chr10_+_3153973 2.80 ENSDART00000183223
hic2
hypermethylated in cancer 2
chr5_-_28149767 2.45 ENSDART00000051515
zgc:110329
zgc:110329
chr20_-_23876291 2.43 ENSDART00000043316
katna1
katanin p60 (ATPase containing) subunit A 1
chr12_-_17863467 2.34 ENSDART00000042006
baiap2l1a
BAI1-associated protein 2-like 1a
chr20_+_1385674 2.31 ENSDART00000145981
mmachc
methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
chr17_-_23709347 2.28 ENSDART00000124661
papss2a
3'-phosphoadenosine 5'-phosphosulfate synthase 2a
chr5_+_3891485 2.20 ENSDART00000129329
ENSDART00000091711
rpain
RPA interacting protein
chr10_+_5268054 2.19 ENSDART00000114491
ror2
receptor tyrosine kinase-like orphan receptor 2
chr22_+_21618121 2.16 ENSDART00000133939
tle2a
transducin like enhancer of split 2a
chr18_+_8912113 2.12 ENSDART00000147467
tmem243a
transmembrane protein 243, mitochondrial a
chr6_-_13022166 2.08 ENSDART00000157139
tmbim1a
transmembrane BAX inhibitor motif containing 1a
chr22_-_31517300 2.04 ENSDART00000164799
slc6a6b
solute carrier family 6 (neurotransmitter transporter), member 6b
chr15_-_28587147 2.00 ENSDART00000156049
ssh2a
slingshot protein phosphatase 2a
chr2_-_31833347 1.92 ENSDART00000109460
nol7
nucleolar protein 7
chr18_+_8912710 1.91 ENSDART00000142866
tmem243a
transmembrane protein 243, mitochondrial a
chr1_+_46509176 1.90 ENSDART00000166028
mcf2la
mcf.2 cell line derived transforming sequence-like a
chr1_-_52790724 1.90 ENSDART00000139577
ENSDART00000100937
patl1
protein associated with topoisomerase II homolog 1 (yeast)
chr18_+_8912536 1.90 ENSDART00000134827
ENSDART00000061904
tmem243a
transmembrane protein 243, mitochondrial a
chr3_-_60856157 1.85 ENSDART00000053502
CABZ01087513.1

chr17_-_21057617 1.83 ENSDART00000148095
ENSDART00000048853
ube2d1a
ubiquitin-conjugating enzyme E2D 1a
chr13_+_9559461 1.82 ENSDART00000047740
wdr32
WD repeat domain 32
chr3_-_33175583 1.77 ENSDART00000126022
rarab
retinoic acid receptor, alpha b
chr17_-_25303486 1.76 ENSDART00000162235
ppie
peptidylprolyl isomerase E (cyclophilin E)
chr17_-_26507289 1.69 ENSDART00000155616
ccser2a
coiled-coil serine-rich protein 2a
chr2_+_4303125 1.69 ENSDART00000161211
ENSDART00000162269
cables1
Cdk5 and Abl enzyme substrate 1
chr1_+_40613297 1.63 ENSDART00000040798
ENSDART00000168067
ENSDART00000130490
naa15b
N(alpha)-acetyltransferase 15, NatA auxiliary subunit b
chr23_-_36449111 1.57 ENSDART00000110478
zgc:174906
zgc:174906
chr8_+_54135642 1.56 ENSDART00000170712
brpf1
bromodomain and PHD finger containing, 1
chr7_-_735118 1.53 ENSDART00000126424
MAP3K11
si:cabz01078036.1
chr20_-_14114078 1.53 ENSDART00000168434
ENSDART00000104032
si:ch211-223m11.2
si:ch211-223m11.2
chr24_-_41267184 1.51 ENSDART00000063504
xylb
xylulokinase homolog (H. influenzae)
chr18_-_11595567 1.51 ENSDART00000098565
CRACR2A
calcium release activated channel regulator 2A
chr13_-_33317323 1.50 ENSDART00000110295
ENSDART00000144848
ENSDART00000136701
tmem234
transmembrane protein 234
chr15_-_16946124 1.49 ENSDART00000154923
hip1
huntingtin interacting protein 1
chr5_+_40835601 1.48 ENSDART00000147767
si:dkey-3h3.3
si:dkey-3h3.3
chr9_+_24920677 1.48 ENSDART00000037025
slc39a10
solute carrier family 39 (zinc transporter), member 10
chr16_-_9897613 1.45 ENSDART00000104058
ncalda
neurocalcin delta a
chr3_-_35865040 1.44 ENSDART00000102952
suz12a
SUZ12 polycomb repressive complex 2a subunit
chr5_+_58455488 1.44 ENSDART00000038602
ENSDART00000127958
slc37a2
solute carrier family 37 (glucose-6-phosphate transporter), member 2
chr25_+_22017182 1.43 ENSDART00000156517
si:dkey-217l24.1
si:dkey-217l24.1
chr13_-_12667220 1.42 ENSDART00000079594
fam241a
family with sequence similarity 241 member A
chr1_-_38361496 1.41 ENSDART00000015323
fbxo8
F-box protein 8
chr4_-_2525916 1.37 ENSDART00000134123
ENSDART00000132581
ENSDART00000019508
csrp2
cysteine and glycine-rich protein 2
chr20_-_2355357 1.36 ENSDART00000085281
EPB41L2
si:ch73-18b11.1
chr4_-_14531687 1.27 ENSDART00000182093
ENSDART00000159447
plxnb2a
plexin b2a
chr16_+_32082359 1.27 ENSDART00000140794
ENSDART00000137029
prpf31
PRP31 pre-mRNA processing factor 31 homolog (yeast)
chr2_-_24069331 1.26 ENSDART00000156972
ENSDART00000181691
ENSDART00000157041
slc12a7a
solute carrier family 12 (potassium/chloride transporter), member 7a
chr6_-_41135215 1.26 ENSDART00000001861
slc6a22.1
solute carrier family 6 member 22, tandem duplicate 1
chr17_-_7218481 1.23 ENSDART00000181967
SAMD5
sterile alpha motif domain containing 5
chr15_-_35930070 1.21 ENSDART00000076229
irs1
insulin receptor substrate 1
chr23_+_9268083 1.16 ENSDART00000055054
acss2
acyl-CoA synthetase short chain family member 2
chr17_+_30843881 1.15 ENSDART00000149600
ENSDART00000148547
tpp1
tripeptidyl peptidase I
chr5_+_42124706 1.10 ENSDART00000020044
ENSDART00000156372
shpk
sedoheptulokinase
chr16_+_32082547 1.09 ENSDART00000190122
prpf31
PRP31 pre-mRNA processing factor 31 homolog (yeast)
chr9_-_16140860 1.08 ENSDART00000142974
myo1b
myosin IB
chr16_-_9897769 1.06 ENSDART00000187044
ncalda
neurocalcin delta a
chr25_+_33063762 1.05 ENSDART00000189974
tln2b
talin 2b
chr22_+_34784075 1.04 ENSDART00000167538
lcor
ligand dependent nuclear receptor corepressor
chr12_-_22400999 1.02 ENSDART00000153194
si:dkey-38p12.3
si:dkey-38p12.3
chr7_+_25003313 1.01 ENSDART00000131935
naa40
N(alpha)-acetyltransferase 40, NatD catalytic subunit, homolog (S. cerevisiae)
chr18_+_22138924 1.00 ENSDART00000183961
ripor1
RHO family interacting cell polarization regulator 1
chr6_+_27667359 1.00 ENSDART00000159624
ENSDART00000049177
rab6ba
RAB6B, member RAS oncogene family a
chr10_+_10972795 0.98 ENSDART00000127331
cdc37l1
cell division cycle 37-like 1
chr8_-_38201415 0.94 ENSDART00000155189
pdlim2
PDZ and LIM domain 2 (mystique)
chr6_+_46406565 0.93 ENSDART00000168440
ENSDART00000131203
ENSDART00000138567
ENSDART00000132845
pbrm1l
polybromo 1, like
chr1_+_594736 0.93 ENSDART00000166731
jam2a
junctional adhesion molecule 2a
chr16_+_11242443 0.92 ENSDART00000024935
gsk3ab
glycogen synthase kinase 3 alpha b
chr20_+_4221978 0.91 ENSDART00000171898
ipcef1
interaction protein for cytohesin exchange factors 1
chr10_+_8554929 0.88 ENSDART00000190849
tbc1d10ab
TBC1 domain family, member 10Ab
chr11_+_37768298 0.88 ENSDART00000166886
sox13
SRY (sex determining region Y)-box 13
chr23_+_30707837 0.87 ENSDART00000016096
dnajc11a
DnaJ (Hsp40) homolog, subfamily C, member 11a
chr15_+_26933196 0.87 ENSDART00000023842
ppm1da
protein phosphatase, Mg2+/Mn2+ dependent, 1Da
chr17_+_7534180 0.83 ENSDART00000187512
shprh
SNF2 histone linker PHD RING helicase
chr11_+_31864921 0.81 ENSDART00000180252
diaph3
diaphanous-related formin 3
chr14_-_48033073 0.81 ENSDART00000193115
ENSDART00000169300
ENSDART00000188036
ENSDART00000183432
ENSDART00000180973
rapgef2
Rap guanine nucleotide exchange factor (GEF) 2
chr17_+_7534365 0.81 ENSDART00000157123
shprh
SNF2 histone linker PHD RING helicase
chr16_+_12812472 0.81 ENSDART00000008535
u2af2a
U2 small nuclear RNA auxiliary factor 2a
chr13_+_35765317 0.80 ENSDART00000100156
ENSDART00000167650
agpat4
1-acylglycerol-3-phosphate O-acyltransferase 4 (lysophosphatidic acid acyltransferase, delta)
chr4_-_2945306 0.80 ENSDART00000128934
ENSDART00000019518
aebp2
AE binding protein 2
chr17_-_15229787 0.78 ENSDART00000039165
styx
serine/threonine/tyrosine interacting protein
chr3_+_40284598 0.75 ENSDART00000009411
bud31
BUD31 homolog (S. cerevisiae)
chr8_+_16990120 0.72 ENSDART00000018934
pde4d
phosphodiesterase 4D, cAMP-specific
chr14_+_21686207 0.68 ENSDART00000034438
ran
RAN, member RAS oncogene family
chr10_+_26834985 0.66 ENSDART00000147518
fam89b
family with sequence similarity 89, member B
chr11_+_1602916 0.64 ENSDART00000184434
ENSDART00000112597
ENSDART00000192165
si:dkey-40c23.2
si:dkey-40c23.3
si:dkey-40c23.2
si:dkey-40c23.3
chr20_+_4222357 0.63 ENSDART00000188331
ipcef1
interaction protein for cytohesin exchange factors 1
chr21_+_13244450 0.63 ENSDART00000146062
specc1lb
sperm antigen with calponin homology and coiled-coil domains 1-like b
chr3_-_1146497 0.62 ENSDART00000149061
si:ch73-211l13.2
si:ch73-211l13.2
chr20_+_23083800 0.62 ENSDART00000132093
usp46
ubiquitin specific peptidase 46
chr7_+_29115890 0.60 ENSDART00000052345
tradd
tnfrsf1a-associated via death domain
chr8_+_26859639 0.60 ENSDART00000133440
prdm2a
PR domain containing 2, with ZNF domain a
chr22_-_784110 0.58 ENSDART00000061775
rbbp5
retinoblastoma binding protein 5
chr5_-_37875636 0.55 ENSDART00000184674
arhgap35b
Rho GTPase activating protein 35b
chr5_-_38384755 0.54 ENSDART00000188573
ENSDART00000051233
mink1
misshapen-like kinase 1
chr15_+_31911989 0.52 ENSDART00000111472
brca2
breast cancer 2, early onset
chr6_+_18367388 0.50 ENSDART00000163394
dgke
diacylglycerol kinase, epsilon
chr14_-_8080416 0.50 ENSDART00000045109
zgc:92242
zgc:92242
chr8_-_2153147 0.50 ENSDART00000124093
si:dkeyp-117b11.1
si:dkeyp-117b11.1
chr3_+_61523035 0.49 ENSDART00000106530
znf1004
zinc finger protein 1004
chr16_-_16237844 0.46 ENSDART00000168747
ENSDART00000111912
rbm12b
RNA binding motif protein 12B
chr7_+_24729558 0.45 ENSDART00000111542
ENSDART00000170100
shroom4
shroom family member 4
chr1_+_47331644 0.44 ENSDART00000053284
bcl9
B cell CLL/lymphoma 9
chr7_-_24995631 0.44 ENSDART00000173955
ENSDART00000173791
rcor2
REST corepressor 2
chr5_-_38384289 0.43 ENSDART00000135260
mink1
misshapen-like kinase 1
chr4_-_18939338 0.42 ENSDART00000132081
ENSDART00000042250
rap1b
RAP1B, member of RAS oncogene family
chr3_-_40284744 0.41 ENSDART00000018626
pdap1b
pdgfa associated protein 1b
chr6_-_55297274 0.41 ENSDART00000184283
ube2c
ubiquitin-conjugating enzyme E2C
chr10_-_35321625 0.40 ENSDART00000131268
rhbdd2
rhomboid domain containing 2
chr7_+_49078890 0.40 ENSDART00000067857
b4galnt4b
beta-1,4-N-acetyl-galactosaminyl transferase 4b
chr3_-_13955878 0.38 ENSDART00000166804
gcdhb
glutaryl-CoA dehydrogenase b
chr14_-_44773864 0.38 ENSDART00000158386
si:dkey-109l4.3
si:dkey-109l4.3
chr6_-_37460178 0.37 ENSDART00000153500
si:dkey-66a8.7
si:dkey-66a8.7
chr24_-_15263142 0.36 ENSDART00000183176
ENSDART00000006930
rttn
rotatin
chr5_+_26221011 0.36 ENSDART00000007587
gtf2h2
general transcription factor IIH, polypeptide 2
chr2_-_24068848 0.35 ENSDART00000145526
slc12a7a
solute carrier family 12 (potassium/chloride transporter), member 7a
chr8_+_30600386 0.35 ENSDART00000164976
specc1la
sperm antigen with calponin homology and coiled-coil domains 1-like a
chr7_+_24573721 0.34 ENSDART00000173938
ENSDART00000173681
si:dkeyp-75h12.7
si:dkeyp-75h12.7
chr10_-_1718395 0.34 ENSDART00000137620
si:ch73-46j18.5
si:ch73-46j18.5
chr25_+_28825657 0.34 ENSDART00000153625
nfybb
nuclear transcription factor Y, beta b
chr3_-_16110351 0.34 ENSDART00000064838
lasp1
LIM and SH3 protein 1
chr25_+_25124684 0.33 ENSDART00000167542
ldha
lactate dehydrogenase A4
chr8_+_35356944 0.31 ENSDART00000143243
si:dkeyp-14d3.1
si:dkeyp-14d3.1
chr8_-_19313510 0.30 ENSDART00000164780
ENSDART00000137133
rgl1
ral guanine nucleotide dissociation stimulator-like 1
chr4_+_21129752 0.30 ENSDART00000169764
syt1a
synaptotagmin Ia
chr23_-_26725637 0.28 ENSDART00000157844
hspg2
heparan sulfate proteoglycan 2
chr22_-_9861531 0.28 ENSDART00000193197
si:dkey-253d23.2
si:dkey-253d23.2
chr15_+_32419303 0.27 ENSDART00000162663
si:dkey-285b23.3
si:dkey-285b23.3
chr3_-_16110100 0.26 ENSDART00000051807
lasp1
LIM and SH3 protein 1
chr1_+_45839927 0.23 ENSDART00000148086
ENSDART00000180413
ENSDART00000048191
ENSDART00000179047
map2k7
mitogen-activated protein kinase kinase 7
chr10_-_25591194 0.23 ENSDART00000131640
tiam1a
T cell lymphoma invasion and metastasis 1a
chr17_+_45654724 0.23 ENSDART00000098952
zgc:162184
zgc:162184
chr16_-_32975951 0.22 ENSDART00000101969
ENSDART00000175149
me1
malic enzyme 1, NADP(+)-dependent, cytosolic
chr22_-_9860792 0.22 ENSDART00000155908
si:dkey-253d23.2
si:dkey-253d23.2
chr4_+_9030609 0.21 ENSDART00000154399
aldh1l2
aldehyde dehydrogenase 1 family, member L2
chr7_-_24520866 0.21 ENSDART00000077039
faah2b
fatty acid amide hydrolase 2b
chr4_-_77380592 0.20 ENSDART00000163149
slco1e1
solute carrier organic anion transporter family, member 1E1
chr11_+_6115621 0.18 ENSDART00000165031
ENSDART00000027666
ENSDART00000161458
nr2f6b
nuclear receptor subfamily 2, group F, member 6b
chr18_-_14337450 0.17 ENSDART00000061435
hsbp1b
heat shock factor binding protein 1b
chr19_-_38830582 0.17 ENSDART00000189966
ENSDART00000183055
adgrb2
adhesion G protein-coupled receptor B2
chr7_+_24520518 0.16 ENSDART00000173604
btr09
bloodthirsty-related gene family, member 9
chr6_+_36942966 0.14 ENSDART00000028895
negr1
neuronal growth regulator 1
chr11_-_16394971 0.13 ENSDART00000180981
ENSDART00000179925
lrig1
leucine-rich repeats and immunoglobulin-like domains 1
chr25_-_31171948 0.13 ENSDART00000184275
FQ976913.1

chr4_-_33071267 0.12 ENSDART00000186314
si:dkeyp-4f2.1
si:dkeyp-4f2.1
chr18_+_6479963 0.11 ENSDART00000092752
ENSDART00000136333
wash1
WAS protein family homolog 1
chr14_+_6429399 0.11 ENSDART00000149783
ENSDART00000148461
abca1b
ATP-binding cassette, sub-family A (ABC1), member 1B
chr9_+_37329036 0.08 ENSDART00000131756
slc15a2
solute carrier family 15 (oligopeptide transporter), member 2
chr9_-_14075868 0.08 ENSDART00000146449
fer1l6
fer-1-like family member 6
chr19_+_20708460 0.08 ENSDART00000034124
rab5aa
RAB5A, member RAS oncogene family, a
chr9_+_8929764 0.08 ENSDART00000102562
ankrd10b
ankyrin repeat domain 10b
chr17_-_27972307 0.08 ENSDART00000062130
ptafr
platelet-activating factor receptor
chr11_-_21267486 0.08 ENSDART00000128681
DYRK3
zgc:172180
chr14_-_33297287 0.06 ENSDART00000045555
ENSDART00000138294
ENSDART00000075056
rab41
RAB41, member RAS oncogene family
chr17_+_25290136 0.05 ENSDART00000173295
kbtbd11
kelch repeat and BTB (POZ) domain containing 11
chr23_+_21544227 0.05 ENSDART00000140253
arhgef10lb
Rho guanine nucleotide exchange factor (GEF) 10-like b
chr6_+_20647155 0.05 ENSDART00000193477
slc19a1
solute carrier family 19 (folate transporter), member 1
chr3_+_21669545 0.05 ENSDART00000156527
crhr1
corticotropin releasing hormone receptor 1
chr16_+_23796612 0.04 ENSDART00000131698
rab13
RAB13, member RAS oncogene family
chr21_+_31150438 0.04 ENSDART00000065366
st6gal1
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr2_+_36862473 0.04 ENSDART00000135624
si:dkey-193b15.8
si:dkey-193b15.8
chr8_+_9149436 0.04 ENSDART00000064090
pnck
pregnancy up-regulated nonubiquitous CaM kinase
chr7_-_26924903 0.04 ENSDART00000124363
alx4a
ALX homeobox 4a
chr9_+_30211038 0.03 ENSDART00000190847
senp7a
SUMO1/sentrin specific peptidase 7a
chr3_-_8144421 0.03 ENSDART00000170603
si:ch211-51i16.3
si:ch211-51i16.3
chr14_-_2036604 0.03 ENSDART00000192446
BX005294.2

chr17_-_7436766 0.03 ENSDART00000162002
grm1b
glutamate receptor, metabotropic 1b
chr5_+_45139196 0.01 ENSDART00000113738
smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2

Network of associatons between targets according to the STRING database.

First level regulatory network of sox12

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:0050428 sulfate assimilation(GO:0000103) purine ribonucleoside bisphosphate metabolic process(GO:0034035) purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.5 1.5 GO:0005997 xylulose metabolic process(GO:0005997)
0.5 1.5 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.5 1.4 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.4 2.4 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.3 2.4 GO:0051013 microtubule severing(GO:0051013)
0.3 2.3 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.3 1.9 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.2 1.6 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.2 0.6 GO:0097095 frontonasal suture morphogenesis(GO:0097095)
0.2 1.2 GO:0006083 acetate metabolic process(GO:0006083) acetyl-CoA biosynthetic process from acetate(GO:0019427)
0.2 0.7 GO:0061015 RNA import into nucleus(GO:0006404) snRNA import into nucleus(GO:0061015)
0.2 0.8 GO:0043393 regulation of protein binding(GO:0043393)
0.1 1.8 GO:0003139 secondary heart field specification(GO:0003139)
0.1 1.0 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.1 2.3 GO:0006767 water-soluble vitamin metabolic process(GO:0006767)
0.1 1.6 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.1 2.2 GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling(GO:0014068)
0.1 0.4 GO:1902804 negative regulation of neurotransmitter secretion(GO:0046929) response to cAMP(GO:0051591) cellular response to cAMP(GO:0071320) negative regulation of synaptic vesicle transport(GO:1902804) negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.1 0.2 GO:0009397 10-formyltetrahydrofolate metabolic process(GO:0009256) 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
0.1 0.6 GO:0032228 regulation of synaptic transmission, GABAergic(GO:0032228)
0.1 1.3 GO:0046660 female sex differentiation(GO:0046660)
0.1 0.4 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.1 1.6 GO:0006884 cell volume homeostasis(GO:0006884)
0.1 0.9 GO:0042407 cristae formation(GO:0042407)
0.1 1.8 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 2.0 GO:0072348 sulfur compound transport(GO:0072348)
0.1 2.1 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.1 1.8 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 0.4 GO:1905066 regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066)
0.0 0.4 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 1.5 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 1.5 GO:0003094 glomerular filtration(GO:0003094)
0.0 3.4 GO:1905037 autophagosome assembly(GO:0000045) autophagosome organization(GO:1905037)
0.0 0.7 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.9 GO:0007520 myoblast fusion(GO:0007520)
0.0 2.2 GO:0044744 protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744) single-organism nuclear import(GO:1902593)
0.0 1.1 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 1.4 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 2.2 GO:0090090 negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.0 1.1 GO:0071222 cellular response to molecule of bacterial origin(GO:0071219) cellular response to lipopolysaccharide(GO:0071222)
0.0 1.0 GO:0050821 protein stabilization(GO:0050821)
0.0 0.1 GO:0048169 regulation of long-term neuronal synaptic plasticity(GO:0048169)
0.0 1.0 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 0.3 GO:0060325 face morphogenesis(GO:0060325)
0.0 1.1 GO:0099515 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.0 0.2 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.5 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 1.9 GO:0032272 negative regulation of actin filament polymerization(GO:0030837) negative regulation of protein polymerization(GO:0032272)
0.0 1.1 GO:0045214 sarcomere organization(GO:0045214)
0.0 1.6 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.0 GO:0098838 folic acid transport(GO:0015884) drug transport(GO:0015893) methotrexate transport(GO:0051958) reduced folate transmembrane transport(GO:0098838)
0.0 0.3 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 2.1 GO:0051604 protein maturation(GO:0051604)
0.0 0.2 GO:0043507 activation of JUN kinase activity(GO:0007257) positive regulation of JUN kinase activity(GO:0043507)
0.0 0.1 GO:0002753 cytoplasmic pattern recognition receptor signaling pathway(GO:0002753)
0.0 0.6 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.0 0.0 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
0.0 0.1 GO:0033700 phospholipid efflux(GO:0033700)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.5 GO:0098890 extrinsic component of postsynaptic membrane(GO:0098890)
0.3 1.6 GO:0031415 NatA complex(GO:0031415)
0.3 2.4 GO:0071005 U2-type precatalytic spliceosome(GO:0071005)
0.2 2.4 GO:0097431 mitotic spindle pole(GO:0097431)
0.2 2.2 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 4.2 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.1 0.9 GO:0016586 RSC complex(GO:0016586)
0.1 4.1 GO:0016605 PML body(GO:0016605)
0.1 0.8 GO:0089701 U2AF(GO:0089701)
0.1 1.6 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1 0.9 GO:0061617 MICOS complex(GO:0061617)
0.1 0.3 GO:0042584 chromaffin granule membrane(GO:0042584)
0.1 1.8 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1 1.1 GO:0005903 brush border(GO:0005903)
0.1 0.4 GO:0000439 core TFIIH complex(GO:0000439)
0.0 1.9 GO:0031941 filamentous actin(GO:0031941)
0.0 0.6 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.3 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.1 GO:0071203 WASH complex(GO:0071203)
0.0 0.1 GO:0098842 postsynaptic early endosome(GO:0098842)
0.0 0.9 GO:0098636 protein complex involved in cell adhesion(GO:0098636)
0.0 1.4 GO:0030018 Z disc(GO:0030018)
0.0 1.6 GO:0000786 nucleosome(GO:0000786)
0.0 1.6 GO:0005925 focal adhesion(GO:0005925)
0.0 1.4 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:0004781 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.5 1.4 GO:0061513 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.3 2.3 GO:0031419 cobalamin binding(GO:0031419)
0.3 1.0 GO:0043998 H2A histone acetyltransferase activity(GO:0043998)
0.2 1.2 GO:0050218 propionate-CoA ligase activity(GO:0050218)
0.2 2.4 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.2 1.6 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1 1.5 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 1.6 GO:0043994 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.1 1.8 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 1.2 GO:0005158 insulin receptor binding(GO:0005158)
0.1 0.6 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 3.3 GO:0005343 organic acid:sodium symporter activity(GO:0005343)
0.1 0.4 GO:0004361 glutaryl-CoA dehydrogenase activity(GO:0004361)
0.1 2.3 GO:0042805 actinin binding(GO:0042805)
0.1 0.8 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.1 0.4 GO:0033842 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity(GO:0033842)
0.1 0.2 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.1 2.2 GO:0017147 Wnt-protein binding(GO:0017147)
0.1 2.4 GO:0017069 snRNA binding(GO:0017069)
0.1 1.6 GO:0015377 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.1 0.8 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.1 0.2 GO:0004470 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.1 1.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 2.2 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.2 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.3 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.2 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.0 0.9 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.9 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 2.8 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 1.8 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 1.5 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.0 0.7 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.4 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 1.0 GO:0051087 chaperone binding(GO:0051087)
0.0 1.8 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.1 GO:0090556 phospholipid-translocating ATPase activity(GO:0004012) phosphatidylcholine-translocating ATPase activity(GO:0090554) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.0 1.4 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.5 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 1.1 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 1.1 GO:0005178 integrin binding(GO:0005178)
0.0 0.0 GO:0008518 reduced folate carrier activity(GO:0008518) methotrexate transporter activity(GO:0015350)
0.0 0.4 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.1 GO:0071916 dipeptide transporter activity(GO:0042936) dipeptide transmembrane transporter activity(GO:0071916)
0.0 0.1 GO:0043014 alpha-tubulin binding(GO:0043014)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 PID REELIN PATHWAY Reelin signaling pathway
0.1 2.9 PID ARF6 PATHWAY Arf6 signaling events
0.1 2.4 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 2.2 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 1.2 PID S1P S1P2 PATHWAY S1P2 pathway
0.1 1.7 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 1.0 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.7 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.4 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.6 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 1.1 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 1.5 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.8 PID CDC42 PATHWAY CDC42 signaling events
0.0 0.5 PID FOXM1 PATHWAY FOXM1 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.2 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 1.9 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1 1.5 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 1.2 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.1 0.6 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.4 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.7 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.7 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 0.8 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.3 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 1.1 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.5 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.5 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.4 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 1.7 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.4 REACTOME MRNA CAPPING Genes involved in mRNA Capping
0.0 0.3 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism