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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for sox13

Z-value: 1.27

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Transcription factors associated with sox13

Gene Symbol Gene ID Gene Info
sox13
ENSDARG00000030297 SRY-box transcription factor 13
sox13
ENSDARG00000112638 SRY-box transcription factor 13

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
sox13dr11_v1_chr11_+_37803773_378037730.929.2e-08Click!

Activity profile of sox13 motif

Sorted Z-values of sox13 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr13_-_24448278 1.38 ENSDART00000057584
slc1a4
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr17_+_12075805 1.36 ENSDART00000155329
cnsta
consortin, connexin sorting protein a
chr20_-_14718801 1.35 ENSDART00000137605
suco
SUN domain containing ossification factor
chr14_-_12071679 1.35 ENSDART00000165581
tmsb1
thymosin beta 1
chr4_-_20108833 1.34 ENSDART00000100867
fam3c
family with sequence similarity 3, member C
chr12_+_48674381 1.32 ENSDART00000105309
uros
uroporphyrinogen III synthase
chr1_+_6646529 1.31 ENSDART00000144641
ENSDART00000103701
ENSDART00000138919
ube2f
ubiquitin-conjugating enzyme E2F (putative)
chr22_-_29906764 1.11 ENSDART00000019786
smc3
structural maintenance of chromosomes 3
chr10_-_8434816 1.11 ENSDART00000108643
tctn1
tectonic family member 1
chr1_-_338445 1.06 ENSDART00000010092
gas6
growth arrest-specific 6
chr20_-_8024582 1.05 ENSDART00000083898
plpp3
phospholipid phosphatase 3
chr1_+_26445615 1.00 ENSDART00000180810
g3bp2
GTPase activating protein (SH3 domain) binding protein 2
chr8_+_7875110 0.99 ENSDART00000167423
ENSDART00000160267
ENSDART00000180490
mbd1a
methyl-CpG binding domain protein 1a
chr1_-_23596391 0.99 ENSDART00000155184
lcorl
ligand dependent nuclear receptor corepressor-like
chr15_-_37543839 0.98 ENSDART00000148870
kmt2bb
lysine (K)-specific methyltransferase 2Bb
chr22_+_12798569 0.98 ENSDART00000005720
stat1a
signal transducer and activator of transcription 1a
chr15_-_33965440 0.95 ENSDART00000163841
lsr
lipolysis stimulated lipoprotein receptor
chr12_+_33395748 0.94 ENSDART00000129458
fasn
fatty acid synthase
chr12_+_20667301 0.90 ENSDART00000144804
mxra7
matrix-remodelling associated 7
chr3_-_31716157 0.89 ENSDART00000193189
ccdc47
coiled-coil domain containing 47
chr10_+_20392083 0.87 ENSDART00000166867
r3hcc1
R3H domain and coiled-coil containing 1
chr14_+_26247319 0.86 ENSDART00000192793
CCDC69
coiled-coil domain containing 69
chr10_+_41986685 0.86 ENSDART00000086165
ENSDART00000171983
setd1ba
SET domain containing 1B, a
chr24_-_2381143 0.84 ENSDART00000144307
rreb1a
ras responsive element binding protein 1a
chr5_+_63302660 0.83 ENSDART00000142131
si:ch73-376l24.2
si:ch73-376l24.2
chr22_+_883678 0.83 ENSDART00000140588
stk38b
serine/threonine kinase 38b
chr18_+_21273749 0.82 ENSDART00000143265
hydin
HYDIN, axonemal central pair apparatus protein
chr12_-_25097520 0.81 ENSDART00000158036
cript
cysteine-rich PDZ-binding protein
chr5_+_44944778 0.80 ENSDART00000130428
ENSDART00000044361
ENSDART00000128825
ENSDART00000124637
ENSDART00000126066
ENSDART00000177635
dmrt1
doublesex and mab-3 related transcription factor 1
chr22_-_6562618 0.80 ENSDART00000106100
zgc:171490
zgc:171490
chr3_+_46479705 0.79 ENSDART00000181564
tyk2
tyrosine kinase 2
chr18_+_27511976 0.79 ENSDART00000132017
ENSDART00000140781
tp53i11b
tumor protein p53 inducible protein 11b
chr5_-_28016805 0.79 ENSDART00000078642
vps37b
vacuolar protein sorting 37 homolog B (S. cerevisiae)
chr18_+_27337994 0.77 ENSDART00000136172
si:dkey-29p10.4
si:dkey-29p10.4
chr12_-_47793857 0.76 ENSDART00000161294
dydc2
DPY30 domain containing 2
chr5_+_66353750 0.76 ENSDART00000143410
si:ch211-261c8.5
si:ch211-261c8.5
chr22_-_881725 0.76 ENSDART00000035514
cept1b
choline/ethanolamine phosphotransferase 1b
chr2_+_1999255 0.75 ENSDART00000153597
ssx2ipa
synovial sarcoma, X breakpoint 2 interacting protein a
chr14_+_21238682 0.75 ENSDART00000054462
ENSDART00000138551
smim19
small integral membrane protein 19
chr1_-_23595779 0.75 ENSDART00000134860
ENSDART00000138852
lcorl
ligand dependent nuclear receptor corepressor-like
chr3_+_32410746 0.73 ENSDART00000025496
rras
RAS related
chr11_-_25733910 0.72 ENSDART00000171935
brpf3a
bromodomain and PHD finger containing, 3a
chr24_-_11506054 0.72 ENSDART00000140217
ENSDART00000106310
prpf4bb
pre-mRNA processing factor 4Bb
chr16_+_45337663 0.71 ENSDART00000147343
ENSDART00000185731
dnase2
deoxyribonuclease II, lysosomal
chr5_+_12590403 0.70 ENSDART00000133167
si:dkey-98f17.5
si:dkey-98f17.5
chr9_+_48821631 0.70 ENSDART00000190236
spc25
SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr1_-_11878845 0.70 ENSDART00000163971
ENSDART00000123431
iqce
IQ motif containing E
chr13_+_39182099 0.70 ENSDART00000131434
fam135a
family with sequence similarity 135, member A
chr14_-_16082806 0.69 ENSDART00000165656
mxd3
MAX dimerization protein 3
chr16_+_7380463 0.69 ENSDART00000029727
ENSDART00000149086
atg5
ATG5 autophagy related 5 homolog (S. cerevisiae)
chr12_-_34435604 0.69 ENSDART00000115088
birc5a
baculoviral IAP repeat containing 5a
chr15_-_33964897 0.69 ENSDART00000172075
ENSDART00000158126
ENSDART00000160456
lsr
lipolysis stimulated lipoprotein receptor
chr8_-_50259448 0.69 ENSDART00000146056
nkx3-1
NK3 homeobox 1
chr12_+_27096835 0.69 ENSDART00000149475
ttll6
tubulin tyrosine ligase-like family, member 6
chr3_+_46479913 0.69 ENSDART00000149755
tyk2
tyrosine kinase 2
chr11_-_3308569 0.69 ENSDART00000036581
cdk2
cyclin-dependent kinase 2
chr5_+_24543862 0.68 ENSDART00000029699
atp6v0a2b
ATPase H+ transporting V0 subunit a2b
chr15_-_20125331 0.68 ENSDART00000152355
med13b
mediator complex subunit 13b
chr20_+_34029820 0.67 ENSDART00000143901
ENSDART00000134305
prg4b
proteoglycan 4b
chr8_+_32389838 0.67 ENSDART00000076350
ENSDART00000146901
mthfd2l
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like
chr20_+_23947004 0.67 ENSDART00000144195
casp8ap2
caspase 8 associated protein 2
chr18_+_44532199 0.67 ENSDART00000135386
st14a
suppression of tumorigenicity 14 (colon carcinoma) a
chr20_+_18947314 0.67 ENSDART00000183632
mtmr9
myotubularin related protein 9
chr1_-_31105376 0.67 ENSDART00000132466
ppp1r9alb
protein phosphatase 1 regulatory subunit 9A-like B
chr17_-_11466700 0.66 ENSDART00000091159
adpgk2
ADP-dependent glucokinase 2
chr8_-_49431939 0.66 ENSDART00000011453
ENSDART00000088240
ENSDART00000114173
sypb
synaptophysin b
chr23_-_6692141 0.66 ENSDART00000161433
baz2a
bromodomain adjacent to zinc finger domain, 2A
chr20_+_38671894 0.66 ENSDART00000146544
mpv17
MpV17 mitochondrial inner membrane protein
chr6_+_12968101 0.65 ENSDART00000013781
mcm6
minichromosome maintenance complex component 6
chr24_+_17269849 0.65 ENSDART00000017605
spag6
sperm associated antigen 6
chr14_-_33859149 0.64 ENSDART00000163877
ocrl
oculocerebrorenal syndrome of Lowe
chr7_+_24006875 0.64 ENSDART00000033755
homezb
homeobox and leucine zipper encoding b
chr22_-_20838011 0.64 ENSDART00000186056
dot1l
DOT1-like histone H3K79 methyltransferase
chr23_+_5565261 0.64 ENSDART00000059307
ENSDART00000169904
smpd2a
sphingomyelin phosphodiesterase 2a, neutral membrane (neutral sphingomyelinase)
chr10_+_37182626 0.64 ENSDART00000137636
ksr1a
kinase suppressor of ras 1a
chr6_+_44197099 0.63 ENSDART00000124168
ppp4r2b
protein phosphatase 4, regulatory subunit 2b
chr7_-_51757085 0.63 ENSDART00000167747
leap2
liver-expressed antimicrobial peptide 2
chr18_+_13077800 0.63 ENSDART00000161153
GAN
gigaxonin
chr2_-_44183613 0.63 ENSDART00000079596
cadm3
cell adhesion molecule 3
chr23_+_31815423 0.62 ENSDART00000075730
ENSDART00000075726
myb
v-myb avian myeloblastosis viral oncogene homolog
chr16_-_54919260 0.62 ENSDART00000156533
kdf1a
keratinocyte differentiation factor 1a
chr14_+_22132388 0.62 ENSDART00000109065
ccng1
cyclin G1
chr14_+_20941534 0.61 ENSDART00000185616
zgc:66433
zgc:66433
chr24_+_33589667 0.61 ENSDART00000152097
dnah5l
dynein, axonemal, heavy chain 5 like
chr8_+_19489854 0.61 ENSDART00000184671
ENSDART00000011258
npl
N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
chr24_-_33366188 0.60 ENSDART00000074161
slc4a2b
solute carrier family 4 (anion exchanger), member 2b
chr8_-_41279326 0.60 ENSDART00000075491
pop5
POP5 homolog, ribonuclease P/MRP subunit
chr22_-_22337382 0.60 ENSDART00000144684
si:ch211-129c21.1
si:ch211-129c21.1
chr22_-_20950448 0.60 ENSDART00000002029
fkbp8
FK506 binding protein 8
chr19_-_10214264 0.60 ENSDART00000053300
ENSDART00000148225
znf865
zinc finger protein 865
chr22_-_20812822 0.60 ENSDART00000193778
dot1l
DOT1-like histone H3K79 methyltransferase
chr21_+_38033226 0.60 ENSDART00000085728
klf8
Kruppel-like factor 8
chr8_-_1838315 0.60 ENSDART00000114476
ENSDART00000140077
pi4kab
phosphatidylinositol 4-kinase, catalytic, alpha b
chr20_+_18943406 0.59 ENSDART00000193590
mtmr9
myotubularin related protein 9
chr5_-_65662996 0.59 ENSDART00000147707
camsap1b
calmodulin regulated spectrin-associated protein 1b
chr10_+_9222476 0.59 ENSDART00000064973
ENSDART00000145879
paqr3b
progestin and adipoQ receptor family member IIIb
chr25_+_13158549 0.59 ENSDART00000167804
si:dkeyp-50b9.1
si:dkeyp-50b9.1
chr9_+_2574122 0.58 ENSDART00000166326
ENSDART00000191822
CIR1
si:ch73-167c12.2
chr21_-_2261720 0.58 ENSDART00000170161
si:ch73-299h12.2
si:ch73-299h12.2
chr1_+_38142354 0.58 ENSDART00000179352
galnt7
UDP-N-acetyl-alpha-D-galactosamine: polypeptide N-acetylgalactosaminyltransferase 7
chr22_+_17606863 0.58 ENSDART00000035670
polr2eb
polymerase (RNA) II (DNA directed) polypeptide E, b
chr24_-_40901410 0.58 ENSDART00000170688
wdr48a
WD repeat domain 48a
chr7_+_23997518 0.57 ENSDART00000173372
ccdc166
coiled-coil domain containing 166
chr8_-_51367298 0.57 ENSDART00000060628
chmp7
charged multivesicular body protein 7
chr17_+_16192486 0.57 ENSDART00000156832
kif13ba
kinesin family member 13Ba
chr24_+_39277043 0.56 ENSDART00000165458
MPRIP
si:ch73-103b11.2
chr12_-_22400999 0.56 ENSDART00000153194
si:dkey-38p12.3
si:dkey-38p12.3
chr15_+_22394074 0.56 ENSDART00000109931
oafa
OAF homolog a (Drosophila)
chr18_+_15876385 0.56 ENSDART00000142527
eea1
early endosome antigen 1
chr13_+_35689749 0.56 ENSDART00000158726
psme4a
proteasome activator subunit 4a
chr4_+_17279966 0.56 ENSDART00000067005
ENSDART00000137487
bcat1
branched chain amino-acid transaminase 1, cytosolic
chr6_-_46735380 0.56 ENSDART00000103455
tarbp2
TAR (HIV) RNA binding protein 2
chr5_+_10084100 0.56 ENSDART00000109236
si:ch211-207k7.4
si:ch211-207k7.4
chr12_-_35582683 0.55 ENSDART00000167933
sec24c
SEC24 homolog C, COPII coat complex component
chr15_-_1844048 0.55 ENSDART00000102410
taf15
TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr13_-_18863680 0.54 ENSDART00000109277
lzts2a
leucine zipper, putative tumor suppressor 2a
chr11_+_13024002 0.54 ENSDART00000104113
btf3l4
basic transcription factor 3-like 4
chr21_-_21790372 0.54 ENSDART00000151094
xrra1
X-ray radiation resistance associated 1
chr3_-_30488063 0.54 ENSDART00000055393
ENSDART00000151367
med25
mediator complex subunit 25
chr11_-_34572202 0.54 ENSDART00000077883
pfkfb4a
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4a
chr24_-_41220538 0.54 ENSDART00000150207
acvr2ba
activin A receptor type 2Ba
chr1_-_25749657 0.54 ENSDART00000191571
map9
microtubule-associated protein 9
chr23_+_2666944 0.53 ENSDART00000192861
CABZ01057928.1

chr5_-_23583446 0.53 ENSDART00000027217
cwc15
CWC15 spliceosome-associated protein homolog (S. cerevisiae)
chr12_+_13319132 0.53 ENSDART00000049167
psme2
proteasome activator subunit 2
chr8_+_35964482 0.52 ENSDART00000129357
ENSDART00000154953
glt1d1
glycosyltransferase 1 domain containing 1
chr2_+_26240631 0.52 ENSDART00000129895
palm1b
paralemmin 1b
chr24_-_41195068 0.52 ENSDART00000121592
acvr2ba
activin A receptor type 2Ba
chr3_+_32411343 0.52 ENSDART00000186287
ENSDART00000141793
rras
RAS related
chr24_+_17069420 0.52 ENSDART00000014787
pip4k2aa
phosphatidylinositol-5-phosphate 4-kinase, type II, alpha a
chr13_+_50375800 0.52 ENSDART00000099537
cox5b2
cytochrome c oxidase subunit Vb 2
chr20_-_40367493 0.51 ENSDART00000075096
smpdl3a
sphingomyelin phosphodiesterase, acid-like 3A
chr25_+_26901149 0.51 ENSDART00000153839
znf800a
zinc finger protein 800a
chr21_+_3244146 0.51 ENSDART00000127740
ctif
CBP80/20-dependent translation initiation factor
chr10_-_17550931 0.51 ENSDART00000145077
ska1
spindle and kinetochore associated complex subunit 1
chr4_-_12477224 0.50 ENSDART00000027756
ENSDART00000182706
ENSDART00000127150
arhgef39
Rho guanine nucleotide exchange factor (GEF) 39
chr14_-_22495604 0.50 ENSDART00000137167
si:ch211-107m4.1
si:ch211-107m4.1
chr21_-_26677834 0.50 ENSDART00000077381
nxf1
nuclear RNA export factor 1
chr15_-_16872600 0.50 ENSDART00000142870
tyw1
tRNA-yW synthesizing protein 1 homolog (S. cerevisiae)
chr25_+_33201727 0.50 ENSDART00000181051
ENSDART00000192378
TPM1 (1 of many)
zgc:171719
chr19_+_4968947 0.49 ENSDART00000003634
ENSDART00000134808
stard3
StAR-related lipid transfer (START) domain containing 3
chr13_+_35690023 0.49 ENSDART00000128865
ENSDART00000130050
psme4a
proteasome activator subunit 4a
chr17_-_10309766 0.49 ENSDART00000160994
ttc6
tetratricopeptide repeat domain 6
chr24_+_31348595 0.49 ENSDART00000160140
ENSDART00000158661
cremb
cAMP responsive element modulator b
chr21_-_25395223 0.49 ENSDART00000016219
ppme1
protein phosphatase methylesterase 1
chr10_+_42542517 0.49 ENSDART00000005496
kctd9b
potassium channel tetramerization domain containing 9b
chr13_-_23074454 0.48 ENSDART00000065652
srgn
serglycin
chr23_+_33947874 0.48 ENSDART00000136104
si:ch211-148l7.4
si:ch211-148l7.4
chr15_-_1843831 0.48 ENSDART00000156718
ENSDART00000154175
taf15
TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr5_+_13308139 0.48 ENSDART00000182189
ydjc
YdjC chitooligosaccharide deacetylase homolog
chr24_+_17270129 0.48 ENSDART00000186729
spag6
sperm associated antigen 6
chr16_-_23346095 0.48 ENSDART00000160546
si:dkey-247k7.2
si:dkey-247k7.2
chr6_-_54126463 0.48 ENSDART00000161059
tusc2a
tumor suppressor candidate 2a
chr3_-_26806032 0.48 ENSDART00000143710
pigq
phosphatidylinositol glycan anchor biosynthesis, class Q
chr2_-_44183451 0.48 ENSDART00000111246
cadm3
cell adhesion molecule 3
chr21_-_2158298 0.48 ENSDART00000182199
gb:ai877918
expressed sequence AI877918
chr22_-_15562933 0.48 ENSDART00000141528
ankmy1
ankyrin repeat and MYND domain containing 1
chr22_+_17399124 0.47 ENSDART00000145769
rabgap1l
RAB GTPase activating protein 1-like
chr11_+_39135050 0.47 ENSDART00000180571
ENSDART00000189685
cdc42
cell division cycle 42
chr20_-_34028967 0.47 ENSDART00000153408
ENSDART00000033817
scyl3
SCY1-like, kinase-like 3
chr2_+_25657958 0.47 ENSDART00000161407
tnika
TRAF2 and NCK interacting kinase a
chr12_+_17439580 0.47 ENSDART00000189257
atad1b
ATPase family, AAA domain containing 1b
chr4_+_9028819 0.47 ENSDART00000102893
aldh1l2
aldehyde dehydrogenase 1 family, member L2
chr6_-_40352215 0.47 ENSDART00000103992
ttll3
tubulin tyrosine ligase-like family, member 3
chr10_-_11012000 0.46 ENSDART00000132995
ak3
adenylate kinase 3
chr6_-_1591002 0.46 ENSDART00000087039
zgc:123305
zgc:123305
chr22_+_1887750 0.46 ENSDART00000180917
si:dkey-15h8.17
si:dkey-15h8.17
chr3_-_23512285 0.45 ENSDART00000159151
BX682558.1

chr19_+_9113932 0.45 ENSDART00000060442
setdb1a
SET domain, bifurcated 1a
chr22_+_789795 0.45 ENSDART00000185230
ENSDART00000192538
ENSDART00000171045
ENSDART00000180188
cry1bb
cryptochrome circadian clock 1bb
chr18_-_3527686 0.45 ENSDART00000169049
capn5a
calpain 5a
chr10_-_41906609 0.45 ENSDART00000102530
kdm2bb
lysine (K)-specific demethylase 2Bb
chr11_+_39935154 0.44 ENSDART00000187653
vamp3
vesicle-associated membrane protein 3 (cellubrevin)
chr11_-_25734417 0.44 ENSDART00000103570
brpf3a
bromodomain and PHD finger containing, 3a
chr2_+_37875789 0.44 ENSDART00000036318
ENSDART00000127679
cbln13
cerebellin 13
chr13_-_48764180 0.44 ENSDART00000167157
si:ch1073-266p11.2
si:ch1073-266p11.2
chr19_-_6083761 0.43 ENSDART00000151185
ENSDART00000143941
gsk3aa
glycogen synthase kinase 3 alpha a
chr13_-_19799824 0.43 ENSDART00000058032
fam204a
family with sequence similarity 204, member A
chr3_-_36440705 0.43 ENSDART00000162875
rogdi
rogdi homolog (Drosophila)
chr25_+_7321675 0.43 ENSDART00000104712
ENSDART00000142934
hmg20a
high mobility group 20A
chr5_-_72058646 0.43 ENSDART00000112955
PRRC2B
proline rich coiled-coil 2B
chr5_+_30759232 0.43 ENSDART00000078018
ruvbl2
RuvB-like AAA ATPase 2
chr4_-_13567387 0.43 ENSDART00000132971
ENSDART00000102010
mdm1
Mdm1 nuclear protein homolog (mouse)
chr2_-_9915814 0.43 ENSDART00000091644
ENSDART00000177556
abi1b
abl-interactor 1b
chr18_+_39327010 0.43 ENSDART00000012164
tmod2
tropomodulin 2
chr13_+_18371208 0.43 ENSDART00000138172
ccar1
cell division cycle and apoptosis regulator 1
chr23_-_7799184 0.42 ENSDART00000190946
ENSDART00000165427
myt1b
myelin transcription factor 1b
chr24_-_17067284 0.42 ENSDART00000111237
armc3
armadillo repeat containing 3
chr9_+_1039215 0.42 ENSDART00000192186
DOCK9 (1 of many)
dedicator of cytokinesis 9
chr11_-_25461336 0.42 ENSDART00000014945
hcfc1a
host cell factor C1a
chr14_+_33049579 0.42 ENSDART00000113470
tex11
testis expressed 11
chr5_-_33039670 0.41 ENSDART00000141361
glipr2
GLI pathogenesis-related 2
chr22_+_9917007 0.41 ENSDART00000063318
blf
bloody fingers
chr1_-_44701313 0.41 ENSDART00000193926
si:dkey-28b4.8
si:dkey-28b4.8
chr16_+_40024883 0.41 ENSDART00000110100
hint3
histidine triad nucleotide binding protein 3
chr24_-_26632171 0.41 ENSDART00000008374
ENSDART00000017384
tnikb
TRAF2 and NCK interacting kinase b
chr16_+_24978203 0.40 ENSDART00000156579
si:dkeyp-84f3.5
si:dkeyp-84f3.5
chr20_-_29474859 0.40 ENSDART00000152906
ENSDART00000045249
scg5
secretogranin V
chr22_-_31517300 0.40 ENSDART00000164799
slc6a6b
solute carrier family 6 (neurotransmitter transporter), member 6b
chr16_-_21903083 0.40 ENSDART00000165849
setdb1b
SET domain, bifurcated 1b

Network of associatons between targets according to the STRING database.

First level regulatory network of sox13

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.3 1.2 GO:2000677 histone H3-K79 methylation(GO:0034729) regulation of transcription regulatory region DNA binding(GO:2000677)
0.3 0.8 GO:0030238 male sex determination(GO:0030238)
0.2 0.7 GO:0043416 regulation of skeletal muscle tissue regeneration(GO:0043416)
0.2 1.3 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.2 0.7 GO:0046048 pyrimidine ribonucleoside diphosphate metabolic process(GO:0009193) UDP metabolic process(GO:0046048)
0.2 0.6 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
0.2 0.6 GO:0043903 targeting of mRNA for destruction involved in RNA interference(GO:0030423) regulation of symbiosis, encompassing mutualism through parasitism(GO:0043903)
0.2 1.0 GO:0035093 spermatid nucleus differentiation(GO:0007289) sperm chromatin condensation(GO:0035092) spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.2 0.5 GO:0031590 wybutosine metabolic process(GO:0031590) wybutosine biosynthetic process(GO:0031591)
0.2 0.6 GO:0071867 response to monoamine(GO:0071867) response to catecholamine(GO:0071869) response to epinephrine(GO:0071871)
0.2 0.5 GO:0042560 10-formyltetrahydrofolate metabolic process(GO:0009256) 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
0.2 0.8 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.1 0.7 GO:0006309 apoptotic DNA fragmentation(GO:0006309) cellular component disassembly involved in execution phase of apoptosis(GO:0006921) apoptotic nuclear changes(GO:0030262)
0.1 1.4 GO:0042989 sequestering of actin monomers(GO:0042989)
0.1 0.6 GO:0009098 leucine biosynthetic process(GO:0009098)
0.1 1.4 GO:0046850 regulation of bone remodeling(GO:0046850)
0.1 0.6 GO:0010482 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.1 0.6 GO:0010692 regulation of alkaline phosphatase activity(GO:0010692) negative regulation of alkaline phosphatase activity(GO:0010693)
0.1 0.4 GO:0061187 regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188)
0.1 0.5 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.1 0.3 GO:1903069 regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903069)
0.1 0.3 GO:1903441 receptor localization to nonmotile primary cilium(GO:0097500) protein localization to ciliary membrane(GO:1903441)
0.1 0.9 GO:0031113 regulation of microtubule polymerization(GO:0031113)
0.1 0.3 GO:0030857 negative regulation of epithelial cell differentiation(GO:0030857) regulation of endothelial cell differentiation(GO:0045601)
0.1 0.4 GO:0003322 pancreatic A cell development(GO:0003322)
0.1 0.6 GO:0045658 regulation of granulocyte differentiation(GO:0030852) regulation of neutrophil differentiation(GO:0045658)
0.1 0.6 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.1 1.1 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.1 0.5 GO:0051881 regulation of mitochondrial membrane potential(GO:0051881)
0.1 0.3 GO:1902767 farnesyl diphosphate biosynthetic process, mevalonate pathway(GO:0010142) isoprenoid biosynthetic process via mevalonate(GO:1902767)
0.1 1.4 GO:0045116 protein neddylation(GO:0045116)
0.1 1.3 GO:0045199 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.1 0.3 GO:0036306 embryonic heart tube elongation(GO:0036306)
0.1 0.4 GO:0007060 male meiosis chromosome segregation(GO:0007060)
0.1 1.2 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.1 1.3 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782) protoporphyrinogen IX metabolic process(GO:0046501)
0.1 0.2 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.1 0.2 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.1 0.6 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.1 1.8 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.1 0.6 GO:0090520 sphingolipid mediated signaling pathway(GO:0090520)
0.1 0.9 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.1 1.0 GO:0034340 response to type I interferon(GO:0034340) type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.1 1.0 GO:0006346 methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.1 0.4 GO:0060420 regulation of heart growth(GO:0060420)
0.1 0.3 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.1 1.0 GO:0051255 spindle midzone assembly(GO:0051255)
0.1 0.3 GO:0008591 regulation of Wnt signaling pathway, calcium modulating pathway(GO:0008591)
0.1 0.8 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.1 0.3 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.1 0.6 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.1 0.3 GO:0060296 regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.1 0.4 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.1 0.6 GO:0006267 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.1 1.5 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.1 0.7 GO:0050667 homocysteine metabolic process(GO:0050667)
0.1 0.2 GO:0002544 granuloma formation(GO:0002432) chronic inflammatory response(GO:0002544) regulation of granuloma formation(GO:0002631) regulation of chronic inflammatory response(GO:0002676)
0.1 0.4 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.1 0.6 GO:0021707 cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.1 0.3 GO:0060784 regulation of cell proliferation involved in tissue homeostasis(GO:0060784)
0.1 0.2 GO:0090076 regulation of twitch skeletal muscle contraction(GO:0014724) regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448) negative regulation of striated muscle contraction(GO:0045988) relaxation of skeletal muscle(GO:0090076)
0.1 0.5 GO:0032488 Cdc42 protein signal transduction(GO:0032488)
0.1 0.5 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.7 GO:0045851 vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452)
0.0 1.3 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 0.3 GO:0045050 protein insertion into ER membrane by stop-transfer membrane-anchor sequence(GO:0045050)
0.0 0.7 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.0 0.6 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.2 GO:0030219 megakaryocyte differentiation(GO:0030219)
0.0 0.3 GO:0038026 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948) reelin-mediated signaling pathway(GO:0038026)
0.0 0.4 GO:0006167 AMP biosynthetic process(GO:0006167)
0.0 0.3 GO:0048730 epidermis morphogenesis(GO:0048730)
0.0 0.5 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.7 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.3 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 0.1 GO:0002369 T cell cytokine production(GO:0002369)
0.0 0.4 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.5 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.2 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.1 GO:0070417 cellular response to cold(GO:0070417)
0.0 0.5 GO:0006003 fructose metabolic process(GO:0006000) fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.1 GO:0001778 plasma membrane repair(GO:0001778) monocyte activation(GO:0042117)
0.0 0.2 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.4 GO:0034394 protein localization to cell surface(GO:0034394)
0.0 0.7 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)
0.0 0.4 GO:0035493 SNARE complex assembly(GO:0035493)
0.0 0.1 GO:0048103 neuronal stem cell division(GO:0036445) somatic stem cell division(GO:0048103)
0.0 0.8 GO:0048168 regulation of neuronal synaptic plasticity(GO:0048168)
0.0 0.2 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 0.5 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.0 0.1 GO:0051204 protein insertion into membrane from inner side(GO:0032978) protein insertion into mitochondrial membrane from inner side(GO:0032979) protein insertion into mitochondrial membrane(GO:0051204)
0.0 0.9 GO:0006482 protein demethylation(GO:0006482) protein dealkylation(GO:0008214)
0.0 0.5 GO:0010165 response to X-ray(GO:0010165)
0.0 0.3 GO:0006517 protein deglycosylation(GO:0006517)
0.0 0.8 GO:0006695 cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)
0.0 0.6 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.1 GO:0033690 positive regulation of osteoblast proliferation(GO:0033690)
0.0 0.2 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.1 GO:0015840 urea transport(GO:0015840)
0.0 0.3 GO:0006382 adenosine to inosine editing(GO:0006382)
0.0 1.1 GO:0032924 activin receptor signaling pathway(GO:0032924)
0.0 0.3 GO:0035278 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.2 GO:0098787 mRNA cleavage involved in mRNA processing(GO:0098787) pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.2 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.4 GO:0006446 regulation of translational initiation(GO:0006446)
0.0 0.1 GO:0008344 adult locomotory behavior(GO:0008344)
0.0 0.4 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.3 GO:0021508 floor plate formation(GO:0021508) floor plate morphogenesis(GO:0033505)
0.0 1.6 GO:0007492 endoderm development(GO:0007492)
0.0 0.4 GO:0048570 notochord morphogenesis(GO:0048570)
0.0 0.1 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.0 0.2 GO:0019731 antibacterial humoral response(GO:0019731)
0.0 0.3 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.2 GO:0030719 P granule organization(GO:0030719)
0.0 0.2 GO:0006537 glutamate biosynthetic process(GO:0006537) glutamine catabolic process(GO:0006543)
0.0 0.1 GO:0072554 endothelial tube morphogenesis(GO:0061154) blood vessel lumenization(GO:0072554)
0.0 0.7 GO:0010389 regulation of G2/M transition of mitotic cell cycle(GO:0010389)
0.0 0.3 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.5 GO:0090307 mitotic spindle assembly(GO:0090307) microtubule cytoskeleton organization involved in mitosis(GO:1902850)
0.0 0.1 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.0 0.9 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 0.0 GO:1904292 regulation of ERAD pathway(GO:1904292)
0.0 0.6 GO:0046883 regulation of hormone secretion(GO:0046883)
0.0 0.1 GO:0045955 negative regulation of calcium ion-dependent exocytosis(GO:0045955) negative regulation of regulated secretory pathway(GO:1903306)
0.0 0.5 GO:0048634 regulation of muscle organ development(GO:0048634)
0.0 0.1 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.0 0.3 GO:0030007 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.0 0.4 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.2 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.3 GO:0002574 thrombocyte differentiation(GO:0002574)
0.0 0.4 GO:0038034 signal transduction in absence of ligand(GO:0038034) extrinsic apoptotic signaling pathway in absence of ligand(GO:0097192)
0.0 0.7 GO:0045766 positive regulation of angiogenesis(GO:0045766)
0.0 0.0 GO:0035462 determination of left/right asymmetry in diencephalon(GO:0035462) determination of left/right asymmetry in nervous system(GO:0035545)
0.0 0.5 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.0 0.6 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.0 0.2 GO:0060729 maintenance of gastrointestinal epithelium(GO:0030277) intestinal epithelial structure maintenance(GO:0060729)
0.0 0.1 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.2 GO:0010765 positive regulation of sodium ion transport(GO:0010765) positive regulation of sodium ion transmembrane transport(GO:1902307) regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288) positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.0 0.2 GO:0006265 DNA topological change(GO:0006265)
0.0 0.4 GO:2000045 regulation of G1/S transition of mitotic cell cycle(GO:2000045)
0.0 0.3 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0 0.3 GO:0048264 determination of ventral identity(GO:0048264)
0.0 0.8 GO:0045930 negative regulation of mitotic cell cycle(GO:0045930)
0.0 0.3 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.0 0.5 GO:0046039 GTP metabolic process(GO:0046039)
0.0 0.1 GO:0010456 cell proliferation in dorsal spinal cord(GO:0010456)
0.0 0.5 GO:0035082 axoneme assembly(GO:0035082)
0.0 0.0 GO:0010447 response to acidic pH(GO:0010447)
0.0 0.4 GO:0072348 sulfur compound transport(GO:0072348)
0.0 0.2 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.3 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 0.3 GO:0006661 phosphatidylinositol biosynthetic process(GO:0006661)
0.0 0.4 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.4 GO:0099500 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.0 0.2 GO:0042537 benzene-containing compound metabolic process(GO:0042537)
0.0 0.1 GO:0071691 cardiac muscle thin filament assembly(GO:0071691)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:1990111 spermatoproteasome complex(GO:1990111)
0.2 0.6 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.2 0.6 GO:0070578 RISC-loading complex(GO:0070578)
0.2 0.6 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.1 0.5 GO:0008537 proteasome activator complex(GO:0008537)
0.1 0.7 GO:0033553 rDNA heterochromatin(GO:0033553)
0.1 1.5 GO:0030893 meiotic cohesin complex(GO:0030893)
0.1 0.7 GO:0031262 Ndc80 complex(GO:0031262)
0.1 0.4 GO:0043291 RAVE complex(GO:0043291)
0.1 0.4 GO:0097255 R2TP complex(GO:0097255)
0.1 0.5 GO:0005818 astral microtubule(GO:0000235) aster(GO:0005818)
0.1 0.7 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.1 0.8 GO:0035145 exon-exon junction complex(GO:0035145)
0.1 0.5 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1 1.1 GO:0048179 activin receptor complex(GO:0048179)
0.1 1.3 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.1 0.2 GO:0033391 chromatoid body(GO:0033391)
0.1 0.3 GO:0097268 cytoophidium(GO:0097268)
0.1 0.4 GO:0000801 central element(GO:0000801)
0.1 1.1 GO:0036038 MKS complex(GO:0036038)
0.1 0.6 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 0.7 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.1 1.2 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1 0.7 GO:0072546 ER membrane protein complex(GO:0072546)
0.1 0.2 GO:0031429 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.1 0.6 GO:0036449 microtubule minus-end(GO:0036449)
0.1 0.2 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.4 GO:1990023 mitotic spindle midzone(GO:1990023)
0.1 0.2 GO:0031673 H zone(GO:0031673)
0.1 0.5 GO:0031526 brush border membrane(GO:0031526)
0.1 0.6 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.4 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 0.4 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.5 GO:0071007 U2-type catalytic step 2 spliceosome(GO:0071007)
0.0 0.6 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.2 GO:1990071 TRAPPII protein complex(GO:1990071)
0.0 0.9 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.2 GO:0042584 chromaffin granule membrane(GO:0042584)
0.0 0.2 GO:0097224 sperm connecting piece(GO:0097224)
0.0 0.5 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.2 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.4 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
0.0 0.2 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.4 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.2 GO:0031415 NatA complex(GO:0031415)
0.0 1.3 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 1.6 GO:0035097 histone methyltransferase complex(GO:0035097)
0.0 0.7 GO:0005876 spindle microtubule(GO:0005876)
0.0 1.2 GO:0016592 mediator complex(GO:0016592)
0.0 0.3 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.0 0.8 GO:0016605 PML body(GO:0016605)
0.0 0.4 GO:0042555 MCM complex(GO:0042555)
0.0 0.4 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.6 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 1.0 GO:0031514 motile cilium(GO:0031514)
0.0 0.2 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.3 GO:0060170 ciliary membrane(GO:0060170)
0.0 1.4 GO:0048786 presynaptic active zone(GO:0048786)
0.0 1.4 GO:0036064 ciliary basal body(GO:0036064)
0.0 0.3 GO:0070822 Sin3-type complex(GO:0070822)
0.0 0.7 GO:0030496 midbody(GO:0030496)
0.0 0.6 GO:0005901 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 0.5 GO:0005930 axoneme(GO:0005930)
0.0 0.3 GO:0032039 integrator complex(GO:0032039)
0.0 0.4 GO:0043186 P granule(GO:0043186)
0.0 0.2 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.1 GO:0002178 palmitoyltransferase complex(GO:0002178)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0071253 connexin binding(GO:0071253)
0.3 1.2 GO:0031151 histone methyltransferase activity (H3-K79 specific)(GO:0031151)
0.2 0.7 GO:0030586 [methionine synthase] reductase activity(GO:0030586)
0.2 1.6 GO:0016504 peptidase activator activity(GO:0016504)
0.2 0.5 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.2 0.5 GO:0070738 protein-glycine ligase activity(GO:0070735) tubulin-glycine ligase activity(GO:0070738)
0.2 0.5 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.2 0.8 GO:0004307 diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307)
0.2 0.6 GO:0033204 ribonuclease P RNA binding(GO:0033204)
0.1 0.6 GO:0052656 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.1 0.6 GO:0070883 pre-miRNA binding(GO:0070883)
0.1 0.5 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.1 0.6 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140) single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity(GO:1990518)
0.1 0.4 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.1 0.3 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.1 0.3 GO:0016713 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.1 0.9 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.1 0.4 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.1 0.3 GO:0061656 SUMO conjugating enzyme activity(GO:0061656)
0.1 0.4 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.1 0.6 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 1.2 GO:0010484 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.1 1.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 0.2 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.1 0.3 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.1 0.7 GO:0004488 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
0.1 0.7 GO:0016889 endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
0.1 1.4 GO:0003785 actin monomer binding(GO:0003785)
0.1 0.3 GO:0003883 CTP synthase activity(GO:0003883)
0.1 0.5 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1 0.7 GO:0030332 cyclin binding(GO:0030332)
0.1 1.1 GO:0017002 activin-activated receptor activity(GO:0017002)
0.1 0.2 GO:0032027 myosin light chain binding(GO:0032027)
0.1 0.6 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.1 0.5 GO:0008494 translation activator activity(GO:0008494)
0.1 0.3 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.1 0.7 GO:0043028 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.1 0.5 GO:0032977 membrane insertase activity(GO:0032977)
0.1 0.4 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.7 GO:0070739 protein-glutamic acid ligase activity(GO:0070739) tubulin-glutamic acid ligase activity(GO:0070740)
0.0 1.3 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.0 0.7 GO:0051117 ATPase binding(GO:0051117)
0.0 1.0 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.3 GO:0072518 Rho-dependent protein serine/threonine kinase activity(GO:0072518)
0.0 0.3 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.1 GO:0000703 oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity(GO:0000703)
0.0 0.4 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.5 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.2 GO:0003988 acetyl-CoA C-acyltransferase activity(GO:0003988)
0.0 0.3 GO:0008506 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.0 0.3 GO:0000995 transcription factor activity, core RNA polymerase III binding(GO:0000995)
0.0 0.5 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439) phosphatidylinositol phosphate 5-phosphatase activity(GO:0034595)
0.0 0.6 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.3 GO:0016972 thiol oxidase activity(GO:0016972)
0.0 0.2 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.0 1.2 GO:0019003 GDP binding(GO:0019003)
0.0 0.4 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.2 GO:0039706 co-receptor binding(GO:0039706)
0.0 0.3 GO:0000217 DNA secondary structure binding(GO:0000217)
0.0 1.6 GO:0061650 ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.0 0.6 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.5 GO:0010181 FMN binding(GO:0010181)
0.0 1.1 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.6 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.0 0.8 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.4 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.2 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.3 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.2 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.6 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.1 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046) core promoter binding(GO:0001047)
0.0 0.9 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.3 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.1 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.2 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 0.4 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0 0.2 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.5 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.3 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.4 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.4 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.6 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.5 GO:0019213 deacetylase activity(GO:0019213)
0.0 0.2 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.2 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.2 GO:0004359 glutaminase activity(GO:0004359)
0.0 0.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.3 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.2 GO:0016278 lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.0 0.4 GO:0016675 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.5 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.4 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0 0.1 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.1 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 1.1 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.7 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.1 GO:0016212 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.0 0.2 GO:0019869 chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.0 0.2 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.3 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor(GO:0016655)
0.0 0.2 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.4 GO:0005343 organic acid:sodium symporter activity(GO:0005343)
0.0 0.2 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.1 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.1 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.1 GO:0008568 microtubule-severing ATPase activity(GO:0008568)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.5 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.1 0.7 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1 1.8 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 1.1 PID ATM PATHWAY ATM pathway
0.0 0.7 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.6 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.9 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.8 PID MYC PATHWAY C-MYC pathway
0.0 0.6 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.7 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.2 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.2 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.5 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.6 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 0.3 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.3 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.4 PID SHP2 PATHWAY SHP2 signaling
0.0 0.4 PID P53 REGULATION PATHWAY p53 pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.5 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.1 1.3 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 1.3 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 0.6 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.1 0.9 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.1 0.4 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1 0.5 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.1 0.8 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.1 1.4 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.6 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 1.3 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.9 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.8 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.3 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.6 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.5 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.7 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.7 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.0 0.7 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.4 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.2 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.7 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.3 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.2 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.3 REACTOME S PHASE Genes involved in S Phase
0.0 0.1 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.7 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.6 REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM Genes involved in Transport of Mature Transcript to Cytoplasm
0.0 0.2 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.1 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.3 REACTOME TELOMERE MAINTENANCE Genes involved in Telomere Maintenance
0.0 0.1 REACTOME RESOLUTION OF AP SITES VIA THE MULTIPLE NUCLEOTIDE PATCH REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the multiple-nucleotide patch replacement pathway