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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for sox14+sox14-1+sox21a

Z-value: 0.66

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Transcription factors associated with sox14+sox14-1+sox21a

Gene Symbol Gene ID Gene Info
sox21a
ENSDARG00000031664 SRY-box transcription factor 21a
sox14
ENSDARG00000070929 SRY-box transcription factor 14
sox21a
ENSDARG00000111842 SRY-box transcription factor 21a
sox14-1
ENSDARG00000111969 SRY-box transcription factor 14

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
sox14dr11_v1_chr6_-_26559921_26559921-0.933.1e-08Click!
FQ377628.2dr11_v1_chr2_-_22575851_22575851-0.933.1e-08Click!
sox21adr11_v1_chr6_+_7414215_74142150.312.2e-01Click!

Activity profile of sox14+sox14-1+sox21a motif

Sorted Z-values of sox14+sox14-1+sox21a motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr20_+_27749133 2.21 ENSDART00000089013
vrtn
vertebrae development associated
chr8_-_32385989 2.09 ENSDART00000143716
ENSDART00000098850
lipg
lipase, endothelial
chr11_-_3535537 1.92 ENSDART00000165329
ENSDART00000009788
ddx19
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 19 (DBP5 homolog, yeast)
chr20_+_54312970 1.64 ENSDART00000024598
ENSDART00000193172
zp2.5
zona pellucida glycoprotein 2, tandem duplicate 5
chr16_+_35535375 1.52 ENSDART00000171675
cited4b
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4b
chr7_-_20611039 1.43 ENSDART00000170422
si:dkey-19b23.8
si:dkey-19b23.8
chr20_+_54295213 1.35 ENSDART00000074085
zp2.3
zona pellucida glycoprotein 2, tandem duplicate 3
chr20_+_54299419 1.33 ENSDART00000056089
ENSDART00000193107
si:zfos-1505d6.3
si:zfos-1505d6.3
chr2_+_38025260 1.32 ENSDART00000075905
hnrnpc
heterogeneous nuclear ribonucleoprotein C
chr16_+_35535171 1.31 ENSDART00000167001
cited4b
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4b
chr20_+_54309148 1.31 ENSDART00000099360
zp2.1
zona pellucida glycoprotein 2, tandem duplicate 1
chr24_-_11076400 1.29 ENSDART00000003195
chmp4c
charged multivesicular body protein 4C
chr15_+_22390076 1.11 ENSDART00000183764
oafa
OAF homolog a (Drosophila)
chr1_+_494297 1.04 ENSDART00000108579
ENSDART00000146732
blzf1
basic leucine zipper nuclear factor 1
chr16_+_26846495 1.03 ENSDART00000078124
trim35-29
tripartite motif containing 35-29
chr16_-_42175617 1.03 ENSDART00000084715
alkbh8
alkB homolog 8, tRNA methyltransferase
chr7_+_22801465 1.01 ENSDART00000052862
ENSDART00000173633
rbm4.1
RNA binding motif protein 4.1
chr12_-_33770299 0.97 ENSDART00000189849
llgl2
lethal giant larvae homolog 2 (Drosophila)
chr15_+_11644866 0.95 ENSDART00000188716
slc1a5
solute carrier family 1 (neutral amino acid transporter), member 5
chr6_+_10338554 0.95 ENSDART00000186936
cobll1a
cordon-bleu WH2 repeat protein-like 1a
chr15_+_29025090 0.94 ENSDART00000131755
si:ch211-137a8.2
si:ch211-137a8.2
chr11_-_11791718 0.94 ENSDART00000180476
cdc6
cell division cycle 6 homolog (S. cerevisiae)
chr3_-_25369557 0.93 ENSDART00000055491
smurf2
SMAD specific E3 ubiquitin protein ligase 2
chr13_-_36761379 0.92 ENSDART00000131534
ENSDART00000029824
map4k5
mitogen-activated protein kinase kinase kinase kinase 5
chr23_-_3758637 0.89 ENSDART00000131536
ENSDART00000139408
ENSDART00000137826
hmga1a
high mobility group AT-hook 1a
chr6_+_59991076 0.86 ENSDART00000163575
CABZ01100888.1

chr18_-_13203351 0.83 ENSDART00000039585
ENSDART00000134920
ENSDART00000142942
klhl36
kelch-like family member 36
chr12_-_2800809 0.83 ENSDART00000152682
ENSDART00000083784
ubtd1b
ubiquitin domain containing 1b
chr15_+_40079468 0.80 ENSDART00000154947
ngef
neuronal guanine nucleotide exchange factor
chr21_+_7100442 0.80 ENSDART00000163869
ppp1r26
protein phosphatase 1, regulatory subunit 26
chr20_-_48877458 0.80 ENSDART00000163271
xrn2
5'-3' exoribonuclease 2
chr20_+_33922339 0.78 ENSDART00000019059
lmx1a
LIM homeobox transcription factor 1, alpha
chr12_+_19958845 0.76 ENSDART00000193248
ercc4
excision repair cross-complementation group 4
chr18_+_46151505 0.75 ENSDART00000015034
ENSDART00000141287
blvrb
biliverdin reductase B
chr12_+_28955766 0.73 ENSDART00000123417
ENSDART00000139347
znf668
zinc finger protein 668
chr21_+_18405585 0.73 ENSDART00000139318
si:dkey-1d7.3
si:dkey-1d7.3
chr1_-_9858508 0.73 ENSDART00000147904
mad1l1
mitotic arrest deficient 1 like 1
chr21_-_21514176 0.72 ENSDART00000031205
nectin3b
nectin cell adhesion molecule 3b
chr19_+_41479990 0.71 ENSDART00000087187
ago2
argonaute RISC catalytic component 2
chr2_-_6112862 0.71 ENSDART00000164269
prdx1
peroxiredoxin 1
chr16_-_41488023 0.70 ENSDART00000169312
cmtm6
CKLF-like MARVEL transmembrane domain containing 6
chr21_-_36453594 0.70 ENSDART00000193176
cnot8
CCR4-NOT transcription complex, subunit 8
chr7_+_38380135 0.70 ENSDART00000174005
rhpn2
rhophilin, Rho GTPase binding protein 2
chr23_-_27050083 0.68 ENSDART00000142324
ENSDART00000133249
ENSDART00000138751
ENSDART00000128718
zgc:66440
zgc:66440
chr1_+_218524 0.68 ENSDART00000109529
tmco3
transmembrane and coiled-coil domains 3
chr23_-_36446307 0.66 ENSDART00000136623
zgc:174906
zgc:174906
chr24_-_16980337 0.65 ENSDART00000183812
klhl15
kelch-like family member 15
chr6_-_4228640 0.64 ENSDART00000162497
ENSDART00000179923
trak2
trafficking protein, kinesin binding 2
chr14_-_246342 0.63 ENSDART00000054823
aurkb
aurora kinase B
chr18_+_20034023 0.63 ENSDART00000139441
morf4l1
mortality factor 4 like 1
chr21_+_12056934 0.62 ENSDART00000125380
zgc:162344
zgc:162344
chr16_-_29690188 0.60 ENSDART00000132351
ENSDART00000004284
scnm1
sodium channel modifier 1
chr16_-_41487589 0.58 ENSDART00000188115
cmtm6
CKLF-like MARVEL transmembrane domain containing 6
chr16_+_54209504 0.57 ENSDART00000020033
xrcc1
X-ray repair complementing defective repair in Chinese hamster cells 1
chr5_-_49951106 0.55 ENSDART00000135954
fam172a
family with sequence similarity 172, member A
chr7_+_16047863 0.55 ENSDART00000188750
immp1l
inner mitochondrial membrane peptidase subunit 1
chr6_-_1591002 0.54 ENSDART00000087039
zgc:123305
zgc:123305
chr10_+_36197968 0.53 ENSDART00000114102
COA4
si:ch211-215a9.5
chr10_+_42589391 0.53 ENSDART00000067689
ENSDART00000075259
fgfr1b
fibroblast growth factor receptor 1b
chr11_-_24063196 0.53 ENSDART00000036513
trib3
tribbles pseudokinase 3
chr12_+_27243059 0.53 ENSDART00000066269
arl4d
ADP-ribosylation factor-like 4D
chr2_-_37134169 0.52 ENSDART00000146123
ENSDART00000146533
ENSDART00000040427
elavl1a
ELAV like RNA binding protein 1a
chr1_-_55118745 0.51 ENSDART00000133915
sertad2a
SERTA domain containing 2a
chr12_-_27588299 0.51 ENSDART00000178023
ENSDART00000066282
dhx8
DEAH (Asp-Glu-Ala-His) box polypeptide 8
chr19_-_2115040 0.51 ENSDART00000020497
snx13
sorting nexin 13
chr25_-_12805295 0.50 ENSDART00000157629
ca5a
carbonic anhydrase Va
chr19_-_20430892 0.50 ENSDART00000111409
tbc1d5
TBC1 domain family, member 5
chr18_-_44935174 0.50 ENSDART00000081025
pex16
peroxisomal biogenesis factor 16
chr25_+_34862225 0.49 ENSDART00000149782
CHST6
zgc:194879
chr21_-_44081540 0.49 ENSDART00000130833
FO704810.1

chr20_+_29690901 0.49 ENSDART00000142669
mboat2b
membrane bound O-acyltransferase domain containing 2b
chr11_-_2270069 0.49 ENSDART00000189005
znf740a
zinc finger protein 740a
chr19_+_13994563 0.48 ENSDART00000164696
tmem222b
transmembrane protein 222b
chr16_+_53387085 0.48 ENSDART00000154223
ENSDART00000101404
kif13a
kinesin family member 13A
chr14_+_16036139 0.47 ENSDART00000190733
prelid1a
PRELI domain containing 1a
chr2_+_36608387 0.47 ENSDART00000159541
pak2a
p21 protein (Cdc42/Rac)-activated kinase 2a
chr20_+_9128256 0.47 ENSDART00000163883
ENSDART00000183072
ENSDART00000187276
bpnt1
bisphosphate nucleotidase 1
chr20_+_29691118 0.45 ENSDART00000164121
mboat2b
membrane bound O-acyltransferase domain containing 2b
chr14_-_21238046 0.44 ENSDART00000129743
si:ch211-175m2.5
si:ch211-175m2.5
chr6_-_25371196 0.44 ENSDART00000187291
PKN2 (1 of many)
zgc:153916
chr10_+_42589707 0.43 ENSDART00000075269
fgfr1b
fibroblast growth factor receptor 1b
chr16_+_25137483 0.43 ENSDART00000155666
znf576.1
zinc finger protein 576, tandem duplicate 1
chr23_-_29668286 0.42 ENSDART00000129248
clstn1
calsyntenin 1
chr13_+_23897975 0.42 ENSDART00000002244
sf3b5
splicing factor 3b, subunit 5
chr10_+_24692076 0.42 ENSDART00000181600
tpte
transmembrane phosphatase with tensin homology
chr9_-_39624173 0.42 ENSDART00000180106
ENSDART00000126766
erbb4b
erb-b2 receptor tyrosine kinase 4b
chr5_-_23715027 0.41 ENSDART00000139020
gbgt1l1
globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 1
chr6_+_4229360 0.41 ENSDART00000191347
ENSDART00000130642
FO082877.1

chr4_-_22749553 0.41 ENSDART00000040033
nup107
nucleoporin 107
chr4_-_14470071 0.41 ENSDART00000143773
plxnb2a
plexin b2a
chr12_+_22576404 0.41 ENSDART00000172053
capgb
capping protein (actin filament), gelsolin-like b
chr20_+_9128829 0.40 ENSDART00000064144
ENSDART00000137450
bpnt1
bisphosphate nucleotidase 1
chr1_+_46405294 0.40 ENSDART00000143228
tubgcp3
tubulin, gamma complex associated protein 3
chr6_+_45300746 0.39 ENSDART00000159176
BX942846.1

chr3_-_5644028 0.39 ENSDART00000019957
ddx39ab
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39Ab
chr17_+_5623514 0.38 ENSDART00000171220
ENSDART00000176083
CU571310.1

chr1_+_55476002 0.38 ENSDART00000152356
si:dkey-9c18.3
si:dkey-9c18.3
chr9_-_7212973 0.37 ENSDART00000133638
mgat4a
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr1_+_54901028 0.36 ENSDART00000137352
zfyve27
zinc finger, FYVE domain containing 27
chr13_-_27620815 0.36 ENSDART00000139904
kcnq5a
potassium voltage-gated channel, KQT-like subfamily, member 5a
chr11_+_13058613 0.34 ENSDART00000161532
zfyve9b
zinc finger, FYVE domain containing 9b
chr19_-_7420867 0.34 ENSDART00000081741
rab25a
RAB25, member RAS oncogene family a
chr9_-_48036 0.33 ENSDART00000165230
ENSDART00000171335
map4k4
mitogen-activated protein kinase kinase kinase kinase 4
chr2_-_26642831 0.33 ENSDART00000132854
ENSDART00000087714
ENSDART00000132651
u2surp
U2 snRNP-associated SURP domain containing
chr12_-_5998898 0.33 ENSDART00000142659
ENSDART00000004896
kat7b
K(lysine) acetyltransferase 7b
chr3_+_27713610 0.33 ENSDART00000019004
arhgdig
Rho GDP dissociation inhibitor (GDI) gamma
chr22_-_876506 0.32 ENSDART00000137522
cept1b
choline/ethanolamine phosphotransferase 1b
chr11_-_44498975 0.32 ENSDART00000173066
ENSDART00000189976
si:ch1073-365p7.2
si:ch1073-365p7.2
chr10_+_32662886 0.32 ENSDART00000099841
rad51c
RAD51 paralog C
chr22_+_4443689 0.31 ENSDART00000185490
ticam1
toll-like receptor adaptor molecule 1
chr9_+_22375331 0.31 ENSDART00000090907
dgkg
diacylglycerol kinase, gamma
chr5_-_29559758 0.31 ENSDART00000051471
ENSDART00000167115
nelfb
negative elongation factor complex member B
chr1_-_494280 0.30 ENSDART00000144406
ercc5
excision repair cross-complementation group 5
chr4_-_2052687 0.30 ENSDART00000138291
ENSDART00000150844
cpsf6
cleavage and polyadenylation specific factor 6
chr1_+_32051581 0.30 ENSDART00000146602
sts
steroid sulfatase (microsomal), isozyme S
chr20_+_38322444 0.30 ENSDART00000161741
ENSDART00000132241
ENSDART00000148936
ENSDART00000149623
stum
stum, mechanosensory transduction mediator homolog
chr9_+_38503233 0.30 ENSDART00000140331
lmln
leishmanolysin-like (metallopeptidase M8 family)
chr5_-_31856681 0.30 ENSDART00000187817
pkn3
protein kinase N3
chr19_-_18418763 0.29 ENSDART00000167271
zgc:112966
zgc:112966
chr3_-_50139860 0.28 ENSDART00000101563
btr02
bloodthirsty-related gene family, member 2
chr19_+_46222918 0.27 ENSDART00000158703
vps28
vacuolar protein sorting 28 (yeast)
chr19_+_13410903 0.27 ENSDART00000165033
ENSDART00000168672
srsf4
serine/arginine-rich splicing factor 4
chr13_-_25819825 0.26 ENSDART00000077612
rel
v-rel avian reticuloendotheliosis viral oncogene homolog
chr13_-_42530656 0.25 ENSDART00000084327
btaf1
BTAF1 RNA polymerase II, B-TFIID transcription factor-associated
chr9_+_22375779 0.25 ENSDART00000183956
dgkg
diacylglycerol kinase, gamma
chr9_-_13963078 0.25 ENSDART00000193398
ENSDART00000061156
raph1a
Ras association (RalGDS/AF-6) and pleckstrin homology domains 1a
chr21_+_22878834 0.25 ENSDART00000065562
pcf11
PCF11 cleavage and polyadenylation factor subunit
chr19_+_46222428 0.24 ENSDART00000183984
vps28
vacuolar protein sorting 28 (yeast)
chr5_-_201600 0.24 ENSDART00000158495
CABZ01088906.1

chr3_+_52078798 0.22 ENSDART00000156882
si:dkey-88e12.3
si:dkey-88e12.3
chr12_+_18458502 0.22 ENSDART00000108745
rnf151
ring finger protein 151
chr13_-_13294847 0.22 ENSDART00000125883
ENSDART00000013534
fgfr3
fibroblast growth factor receptor 3
chr13_-_38088627 0.20 ENSDART00000175268
CT027676.1

chr5_+_24156170 0.19 ENSDART00000136570
slc25a15b
solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15b
chr21_+_37436907 0.19 ENSDART00000182611
ENSDART00000076328
pgrmc1
progesterone receptor membrane component 1
chr4_-_77380592 0.18 ENSDART00000163149
slco1e1
solute carrier organic anion transporter family, member 1E1
chr8_-_20243389 0.18 ENSDART00000184904
acer1
alkaline ceramidase 1
chr1_-_48615105 0.18 ENSDART00000189744
LO017711.1

chr1_+_6817292 0.17 ENSDART00000145822
ENSDART00000092118
erbb4a
erb-b2 receptor tyrosine kinase 4a
chr18_+_17725410 0.17 ENSDART00000090608
rspry1
ring finger and SPRY domain containing 1
chr22_+_17536989 0.17 ENSDART00000149531
hnrnpm
heterogeneous nuclear ribonucleoprotein M
chr7_+_67381912 0.16 ENSDART00000167564
nfat5b
nuclear factor of activated T cells 5b
chr6_+_37623693 0.16 ENSDART00000144812
ENSDART00000182709
tubgcp5
tubulin, gamma complex associated protein 5
chr1_-_18848955 0.16 ENSDART00000109294
ENSDART00000146410
zgc:195282
zgc:195282
chr23_+_19213472 0.16 ENSDART00000185985
apobec2b
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2b
chr7_+_25825667 0.16 ENSDART00000149835
mtm1
myotubularin 1
chr11_-_36957127 0.16 ENSDART00000168528
cacna1da
calcium channel, voltage-dependent, L type, alpha 1D subunit, a
chr9_-_9960940 0.15 ENSDART00000092164
prmt2
protein arginine methyltransferase 2
chr1_-_56717813 0.15 ENSDART00000159196
FO681314.1

chr9_-_2936017 0.14 ENSDART00000102823
zak
sterile alpha motif and leucine zipper containing kinase AZK
chr7_-_27696958 0.14 ENSDART00000173470
calca
calcitonin/calcitonin-related polypeptide, alpha
chr25_+_27405738 0.14 ENSDART00000183266
ENSDART00000115139
pot1
protection of telomeres 1 homolog
chr24_-_21914276 0.14 ENSDART00000128687
c1qtnf9
C1q and TNF related 9
chr13_-_20519001 0.13 ENSDART00000168955
gfra1a
gdnf family receptor alpha 1a
chr5_+_43782267 0.13 ENSDART00000130355
nos2a
nitric oxide synthase 2a, inducible
chr25_+_32474031 0.13 ENSDART00000152124
sqor
sulfide quinone oxidoreductase
chr14_-_10321851 0.13 ENSDART00000143382
il1rapl2
interleukin 1 receptor accessory protein-like 2
chr2_-_39017838 0.13 ENSDART00000048838
rbp2b
retinol binding protein 2b, cellular
chr23_-_6641223 0.13 ENSDART00000023793
mipb
major intrinsic protein of lens fiber b
chr7_-_59047720 0.12 ENSDART00000184831
CR376779.1

chr7_-_72426484 0.12 ENSDART00000190063
rph3ab
rabphilin 3A homolog (mouse), b
chr11_+_14280598 0.12 ENSDART00000163033
si:ch211-262i1.3
si:ch211-262i1.3
chr19_+_43716607 0.11 ENSDART00000133199
cap1
CAP, adenylate cyclase-associated protein 1 (yeast)
chr9_-_51436377 0.11 ENSDART00000006612
tbr1b
T-box, brain, 1b
chr8_-_46457233 0.11 ENSDART00000113214
sult1st7
sulfotransferase family 1, cytosolic sulfotransferase 7
chr15_+_17623115 0.11 ENSDART00000062378
adamts15b
ADAM metallopeptidase with thrombospondin type 1 motif, 15b
chr13_+_7292061 0.11 ENSDART00000179504
CABZ01072077.1
Danio rerio neuroblast differentiation-associated protein AHNAK-like (LOC795051), mRNA.
chr25_+_35155676 0.11 ENSDART00000114598
zgc:112234
zgc:112234
chr9_-_11560110 0.10 ENSDART00000176941
cryba2b
crystallin, beta A2b
chr19_+_43715911 0.10 ENSDART00000006344
cap1
CAP, adenylate cyclase-associated protein 1 (yeast)
chr14_+_23717165 0.10 ENSDART00000006373
ndfip1
Nedd4 family interacting protein 1
chr8_-_13541514 0.10 ENSDART00000063834
zgc:86586
zgc:86586
chr18_-_33254039 0.09 ENSDART00000099130
si:ch211-229c8.4
si:ch211-229c8.4
chr8_+_43852743 0.09 ENSDART00000186485
AL808129.2

chr2_-_51500957 0.09 ENSDART00000172481
pigrl3.5
polymeric immunoglobulin receptor-like 3.5
chr21_+_26390549 0.09 ENSDART00000185643
tmsb
thymosin, beta
chr6_-_48473395 0.09 ENSDART00000185096
ppm1j
protein phosphatase, Mg2+/Mn2+ dependent, 1J
chr12_-_4346085 0.09 ENSDART00000112433
ca15c
carbonic anhydrase XV c
chr5_-_57528943 0.09 ENSDART00000130320
pisd
phosphatidylserine decarboxylase
chr16_-_17056630 0.09 ENSDART00000138715
plekhg6
pleckstrin homology domain containing, family G (with RhoGef domain) member 6
chr2_-_25159309 0.09 ENSDART00000137290
si:dkey-223d7.6
si:dkey-223d7.6
chr10_-_25628555 0.09 ENSDART00000143978
tiam1a
T cell lymphoma invasion and metastasis 1a
chr16_-_24703603 0.09 ENSDART00000131167
negaly6
neuromast-expressed gpi-anchored lymphocyte antigen 6
chr4_-_36139585 0.09 ENSDART00000132071
znf992
zinc finger protein 992
chr16_-_24703855 0.09 ENSDART00000182422
negaly6
neuromast-expressed gpi-anchored lymphocyte antigen 6
chr22_-_23781083 0.08 ENSDART00000166563
ENSDART00000170458
ENSDART00000166158
ENSDART00000171246
cfhl3
complement factor H like 3
chr14_-_33095917 0.08 ENSDART00000074720
dlg3
discs, large homolog 3 (Drosophila)
chr12_-_19862912 0.08 ENSDART00000145788
shisa9a
shisa family member 9a
chr16_-_42303856 0.08 ENSDART00000180030
ppox
protoporphyrinogen oxidase
chr2_-_28420415 0.08 ENSDART00000183857
CABZ01056051.1

chr4_+_69262318 0.08 ENSDART00000188841
si:ch211-209j12.6
si:ch211-209j12.6
chr22_-_15693085 0.08 ENSDART00000141861
si:ch1073-396h14.1
si:ch1073-396h14.1
chr18_+_33570170 0.08 ENSDART00000133276
si:dkey-47k20.3
si:dkey-47k20.3
chr16_+_42464613 0.07 ENSDART00000162454
si:ch211-215k15.4
si:ch211-215k15.4
chr21_-_16113477 0.07 ENSDART00000147588
cyb561a3b
cytochrome b561 family, member A3b
chr22_-_10050856 0.07 ENSDART00000144811
zgc:174564
zgc:174564
chr1_-_33557915 0.07 ENSDART00000075632
creb1a
cAMP responsive element binding protein 1a
chr7_-_30694177 0.07 ENSDART00000191633
myo1ea
myosin IE, a
chr21_+_21791343 0.06 ENSDART00000151654
neu3.1
sialidase 3 (membrane sialidase), tandem duplicate 1
chr6_+_30668098 0.06 ENSDART00000112294
ttc22
tetratricopeptide repeat domain 22

Network of associatons between targets according to the STRING database.

First level regulatory network of sox14+sox14-1+sox21a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 0.4 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.3 0.8 GO:1901255 nucleotide-excision repair involved in interstrand cross-link repair(GO:1901255)
0.2 0.6 GO:0044878 B cell apoptotic process(GO:0001783) regulation of B cell apoptotic process(GO:0002902) abscission(GO:0009838) mitotic cytokinesis checkpoint(GO:0044878) regulation of lymphocyte apoptotic process(GO:0070228)
0.2 1.0 GO:0008594 photoreceptor cell morphogenesis(GO:0008594) negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.2 0.5 GO:0000390 spliceosomal complex disassembly(GO:0000390)
0.2 0.5 GO:0010660 negative regulation of muscle cell apoptotic process(GO:0010656) muscle cell apoptotic process(GO:0010657) striated muscle cell apoptotic process(GO:0010658) regulation of muscle cell apoptotic process(GO:0010660) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664)
0.2 0.6 GO:0043968 histone H2A acetylation(GO:0043968)
0.2 0.9 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.1 0.7 GO:0098795 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.1 1.9 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.1 2.1 GO:0019433 triglyceride catabolic process(GO:0019433)
0.1 0.9 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.1 0.6 GO:0000012 single strand break repair(GO:0000012)
0.1 0.6 GO:0098957 anterograde axonal transport of mitochondrion(GO:0098957)
0.1 0.4 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.1 0.3 GO:0035666 regulation of natural killer cell activation(GO:0032814) positive regulation of natural killer cell activation(GO:0032816) TRIF-dependent toll-like receptor signaling pathway(GO:0035666)
0.1 0.3 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.1 0.3 GO:0046824 regulation of nucleobase-containing compound transport(GO:0032239) positive regulation of nucleobase-containing compound transport(GO:0032241) positive regulation of nucleocytoplasmic transport(GO:0046824) regulation of RNA export from nucleus(GO:0046831) positive regulation of RNA export from nucleus(GO:0046833) messenger ribonucleoprotein complex assembly(GO:1990120)
0.1 0.4 GO:0048011 neurotrophin TRK receptor signaling pathway(GO:0048011)
0.1 1.8 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.1 0.7 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.1 0.5 GO:0031048 chromatin silencing by small RNA(GO:0031048)
0.1 0.5 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.1 0.7 GO:0071450 response to superoxide(GO:0000303) response to oxygen radical(GO:0000305) removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.1 0.2 GO:0000066 mitochondrial ornithine transport(GO:0000066) mitochondrial L-ornithine transmembrane transport(GO:1990575)
0.1 0.7 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.1 1.0 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.1 0.2 GO:0043388 positive regulation of DNA binding(GO:0043388)
0.0 0.5 GO:0072386 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0 0.3 GO:0000730 DNA recombinase assembly(GO:0000730)
0.0 1.0 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 0.1 GO:0019418 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.0 0.2 GO:2000815 regulation of mRNA stability involved in response to stress(GO:0010610) regulation of mRNA stability involved in response to oxidative stress(GO:2000815)
0.0 0.9 GO:0007020 microtubule nucleation(GO:0007020)
0.0 0.8 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.2 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 0.1 GO:2000279 negative regulation of DNA biosynthetic process(GO:2000279)
0.0 0.5 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.4 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.3 GO:1902038 positive regulation of hematopoietic stem cell differentiation(GO:1902038)
0.0 0.8 GO:0046855 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855) inositol phosphate catabolic process(GO:0071545)
0.0 1.0 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.0 0.7 GO:0007286 spermatid development(GO:0007286)
0.0 0.2 GO:0032570 ovulation(GO:0030728) response to progesterone(GO:0032570)
0.0 0.6 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.4 GO:0030259 lipid glycosylation(GO:0030259)
0.0 0.1 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.2 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 0.1 GO:0030825 regulation of cGMP metabolic process(GO:0030823) positive regulation of cGMP metabolic process(GO:0030825) regulation of cGMP biosynthetic process(GO:0030826) positive regulation of cGMP biosynthetic process(GO:0030828) regulation of guanylate cyclase activity(GO:0031282) positive regulation of guanylate cyclase activity(GO:0031284)
0.0 0.1 GO:0021877 forebrain neuron fate commitment(GO:0021877)
0.0 0.2 GO:0030810 activation of adenylate cyclase activity(GO:0007190) positive regulation of cyclic nucleotide metabolic process(GO:0030801) positive regulation of cyclic nucleotide biosynthetic process(GO:0030804) positive regulation of nucleotide biosynthetic process(GO:0030810) positive regulation of cAMP metabolic process(GO:0030816) positive regulation of cAMP biosynthetic process(GO:0030819) positive regulation of cyclase activity(GO:0031281) positive regulation of adenylate cyclase activity(GO:0045762) positive regulation of lyase activity(GO:0051349) positive regulation of purine nucleotide biosynthetic process(GO:1900373)
0.0 0.5 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.0 0.2 GO:0046512 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.0 0.3 GO:0097324 melanocyte migration(GO:0097324)
0.0 0.4 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.2 GO:0036065 fucosylation(GO:0036065)
0.0 0.1 GO:0006833 water transport(GO:0006833)
0.0 0.5 GO:0007031 peroxisome organization(GO:0007031)
0.0 0.4 GO:0051014 actin filament severing(GO:0051014)
0.0 0.4 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 1.4 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.2 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173) inositol phosphate-mediated signaling(GO:0048016)
0.0 0.6 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.5 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.1 0.4 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.1 0.5 GO:0000931 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.1 0.7 GO:0005845 mRNA cap binding complex(GO:0005845)
0.1 0.5 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.1 0.6 GO:0032133 chromosome passenger complex(GO:0032133)
0.1 0.3 GO:0033065 Rad51C-XRCC3 complex(GO:0033065)
0.1 0.3 GO:0042382 paraspeckles(GO:0042382)
0.1 1.3 GO:0000815 ESCRT III complex(GO:0000815)
0.1 0.4 GO:0032584 growth cone membrane(GO:0032584)
0.1 1.9 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 0.7 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.1 0.6 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.9 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.4 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.3 GO:0032021 NELF complex(GO:0032021)
0.0 0.6 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.5 GO:0000813 ESCRT I complex(GO:0000813)
0.0 1.0 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.7 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.4 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.5 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 0.2 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.0 1.9 GO:0016607 nuclear speck(GO:0016607)
0.0 2.1 GO:0005769 early endosome(GO:0005769)
0.0 0.5 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.5 GO:0031970 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 3.1 GO:0000785 chromatin(GO:0000785)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.3 1.3 GO:0035197 siRNA binding(GO:0035197)
0.2 0.8 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.2 2.1 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.2 0.5 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.2 0.9 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 1.1 GO:0051920 peroxiredoxin activity(GO:0051920)
0.1 0.8 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.1 0.4 GO:0043621 protein self-association(GO:0043621)
0.1 0.6 GO:0035173 histone kinase activity(GO:0035173)
0.1 1.2 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.1 0.3 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 0.2 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 0.4 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.1 0.5 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.1 0.3 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307)
0.1 0.3 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.1 1.0 GO:0003785 actin monomer binding(GO:0003785)
0.1 1.0 GO:0045159 myosin II binding(GO:0045159)
0.1 0.9 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.7 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.1 GO:0070224 sulfide:quinone oxidoreductase activity(GO:0070224)
0.0 0.9 GO:0008252 nucleotidase activity(GO:0008252)
0.0 2.9 GO:0003724 RNA helicase activity(GO:0003724)
0.0 0.1 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.0 0.6 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.2 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.7 GO:0015299 solute:proton antiporter activity(GO:0015299)
0.0 0.1 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.0 0.6 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.6 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.2 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.6 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 2.0 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.2 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.1 GO:0050699 WW domain binding(GO:0050699)
0.0 0.8 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.1 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 0.2 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 2.7 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 0.2 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.6 GO:0003684 damaged DNA binding(GO:0003684)
0.0 1.6 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.1 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.4 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.1 GO:0015250 water channel activity(GO:0015250)
0.0 0.3 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.3 GO:0004698 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.0 0.2 GO:0000993 RNA polymerase II core binding(GO:0000993)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.9 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.3 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.8 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.9 PID BMP PATHWAY BMP receptor signaling
0.0 1.2 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 1.3 PID TNF PATHWAY TNF receptor signaling pathway
0.0 1.5 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.9 PID ATR PATHWAY ATR signaling pathway
0.0 0.3 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.7 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.0 0.1 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.7 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.4 PID RHOA REG PATHWAY Regulation of RhoA activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 0.5 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 0.9 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 0.8 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 0.9 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.1 0.6 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.7 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.5 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 1.1 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.6 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.0 1.1 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 1.0 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.3 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.2 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 1.3 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.4 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.3 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 1.8 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.6 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.5 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.8 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 2.0 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.3 REACTOME SIGNALING BY FGFR1 MUTANTS Genes involved in Signaling by FGFR1 mutants