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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for sox17

Z-value: 0.52

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Transcription factors associated with sox17

Gene Symbol Gene ID Gene Info
sox17
ENSDARG00000101717 SRY-box transcription factor 17

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
sox17dr11_v1_chr7_-_58776400_587764000.087.5e-01Click!

Activity profile of sox17 motif

Sorted Z-values of sox17 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr14_-_31854830 0.65 ENSDART00000148550
arhgef6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr12_-_3077395 0.54 ENSDART00000002867
ENSDART00000126315
rfng
RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr16_-_41717063 0.54 ENSDART00000084610
cep85
centrosomal protein 85
chr5_-_67349916 0.53 ENSDART00000144092
mlxip
MLX interacting protein
chr7_+_38349667 0.52 ENSDART00000010046
rhpn2
rhophilin, Rho GTPase binding protein 2
chr7_-_39378903 0.51 ENSDART00000173659
slc8b1
solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
chr3_-_40976288 0.51 ENSDART00000193553
cyp3c1
cytochrome P450, family 3, subfamily c, polypeptide 1
chr11_-_44979281 0.50 ENSDART00000190972
ldb1b
LIM-domain binding 1b
chr25_+_3104959 0.50 ENSDART00000167130
rab3il1
RAB3A interacting protein (rabin3)-like 1
chr15_-_47468085 0.49 ENSDART00000164438
inppl1a
inositol polyphosphate phosphatase-like 1a
chr9_+_38457806 0.47 ENSDART00000142512
mcm3ap
minichromosome maintenance complex component 3 associated protein
chr7_+_66884570 0.47 ENSDART00000082664
sbf2
SET binding factor 2
chr15_-_37543591 0.47 ENSDART00000180400
kmt2bb
lysine (K)-specific methyltransferase 2Bb
chr20_+_4222357 0.46 ENSDART00000188331
ipcef1
interaction protein for cytohesin exchange factors 1
chr15_-_37543839 0.46 ENSDART00000148870
kmt2bb
lysine (K)-specific methyltransferase 2Bb
chr11_-_27537593 0.45 ENSDART00000173444
ENSDART00000172895
ENSDART00000088177
ptpdc1a
protein tyrosine phosphatase domain containing 1a
chr2_+_51818039 0.45 ENSDART00000170353
acvr2bb
activin A receptor type 2Bb
chr20_+_4221978 0.45 ENSDART00000171898
ipcef1
interaction protein for cytohesin exchange factors 1
chr19_-_18135724 0.44 ENSDART00000186609
cbx3a
chromobox homolog 3a (HP1 gamma homolog, Drosophila)
chr9_-_16218097 0.44 ENSDART00000190503
myo1b
myosin IB
chr20_-_18794789 0.44 ENSDART00000003834
ccm2
cerebral cavernous malformation 2
chr3_-_40976463 0.42 ENSDART00000128450
ENSDART00000018676
cyp3c1
cytochrome P450, family 3, subfamily c, polypeptide 1
chr22_+_12361317 0.42 ENSDART00000189963
ENSDART00000159614
r3hdm1
R3H domain containing 1
chr22_+_12361489 0.40 ENSDART00000182483
r3hdm1
R3H domain containing 1
chr13_-_35765028 0.39 ENSDART00000157391
erlec1
endoplasmic reticulum lectin 1
chr4_-_3145359 0.39 ENSDART00000112210
plekha5
pleckstrin homology domain containing, family A member 5
chr3_+_30922947 0.38 ENSDART00000184060
cldni
claudin i
chr3_+_35005730 0.37 ENSDART00000029451
prkcbb
protein kinase C, beta b
chr6_+_30533504 0.37 ENSDART00000155842
wwc3
WWC family member 3
chr17_-_23895026 0.37 ENSDART00000122108
pdzd8
PDZ domain containing 8
chr16_+_50741154 0.37 ENSDART00000101627
IGLON5
zgc:110372
chr21_-_2158298 0.37 ENSDART00000182199
gb:ai877918
expressed sequence AI877918
chr10_-_3258073 0.36 ENSDART00000113162
pi4kaa
phosphatidylinositol 4-kinase, catalytic, alpha a
chr23_+_1414893 0.36 ENSDART00000173020
utrn
utrophin
chr1_+_53321878 0.36 ENSDART00000143909
tbc1d9
TBC1 domain family, member 9 (with GRAM domain)
chr10_-_8434816 0.34 ENSDART00000108643
tctn1
tectonic family member 1
chr18_+_38807239 0.33 ENSDART00000184332
fam214a
family with sequence similarity 214, member A
chr6_+_4299164 0.33 ENSDART00000159759
nbeal1
neurobeachin-like 1
chr2_+_36007449 0.33 ENSDART00000161837
lamc2
laminin, gamma 2
chr12_-_7253270 0.32 ENSDART00000035762
ube2d1b
ubiquitin-conjugating enzyme E2D 1b
chr5_-_69004007 0.32 ENSDART00000137443
ank1a
ankyrin 1, erythrocytic a
chr5_+_53691803 0.32 ENSDART00000163256
taf6
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr1_-_46650022 0.32 ENSDART00000148759
ENSDART00000053222
rcbtb1
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
chr19_-_25114701 0.32 ENSDART00000149035
ptp4a3
protein tyrosine phosphatase type IVA, member 3
chr8_+_23147218 0.32 ENSDART00000030920
ENSDART00000141175
ENSDART00000146264
gid8a
GID complex subunit 8 homolog a (S. cerevisiae)
chr23_+_30730121 0.31 ENSDART00000134141
asxl1
additional sex combs like transcriptional regulator 1
chr23_+_24973773 0.31 ENSDART00000047020
casp9
caspase 9, apoptosis-related cysteine peptidase
chr19_+_46222428 0.31 ENSDART00000183984
vps28
vacuolar protein sorting 28 (yeast)
chr20_+_40457599 0.31 ENSDART00000017553
serinc1
serine incorporator 1
chr5_+_51833305 0.31 ENSDART00000165276
ENSDART00000166443
papd4
PAP associated domain containing 4
chr10_+_15454745 0.30 ENSDART00000129441
ENSDART00000123935
ENSDART00000163446
ENSDART00000087680
ENSDART00000193752
erbin
erbb2 interacting protein
chr5_+_51833132 0.30 ENSDART00000167491
papd4
PAP associated domain containing 4
chr10_-_7988396 0.30 ENSDART00000141445
ENSDART00000024282
ewsr1a
EWS RNA-binding protein 1a
chr16_-_28658341 0.30 ENSDART00000148456
abcb4
ATP-binding cassette, sub-family B (MDR/TAP), member 4
chr15_+_20344670 0.30 ENSDART00000158986
plekhg2
pleckstrin homology domain containing, family G (with RhoGef domain) member 2
chr6_-_7107868 0.30 ENSDART00000171123
nhej1
nonhomologous end-joining factor 1
chr2_+_26240631 0.29 ENSDART00000129895
palm1b
paralemmin 1b
chr23_-_24542156 0.29 ENSDART00000132265
atp13a2
ATPase 13A2
chr8_-_44611357 0.29 ENSDART00000063396
bag4
BCL2 associated athanogene 4
chr21_+_6328801 0.29 ENSDART00000163577
fnbp1b
formin binding protein 1b
chr5_-_68495967 0.29 ENSDART00000188107
ephb4a
eph receptor B4a
chr21_+_12036238 0.29 ENSDART00000102463
ENSDART00000155426
zgc:162344
zgc:162344
chr4_-_2975461 0.29 ENSDART00000150794
plekha5
pleckstrin homology domain containing, family A member 5
chr6_+_55428924 0.29 ENSDART00000018270
ncoa5
nuclear receptor coactivator 5
chr19_+_27970292 0.29 ENSDART00000103887
ENSDART00000145549
med10
mediator complex subunit 10
chr18_-_46183462 0.28 ENSDART00000021192
kcnk6
potassium channel, subfamily K, member 6
chr2_+_22409249 0.28 ENSDART00000182915
zgc:56628
zgc:56628
chr13_-_31687925 0.28 ENSDART00000085989
trmt5
TRM5 tRNA methyltransferase 5 homolog (S. cerevisiae)
chr22_-_14161309 0.28 ENSDART00000133365
si:ch211-246m6.5
si:ch211-246m6.5
chr24_-_16979728 0.28 ENSDART00000005331
klhl15
kelch-like family member 15
chr5_-_15264007 0.27 ENSDART00000180641
gnb1l
guanine nucleotide binding protein (G protein), beta polypeptide 1-like
chr5_+_36896933 0.27 ENSDART00000151984
srsf7a
serine/arginine-rich splicing factor 7a
chr17_+_13031497 0.27 ENSDART00000115208
fbxo33
F-box protein 33
chr15_-_30984804 0.27 ENSDART00000157005
nf1a
neurofibromin 1a
chr20_+_18945057 0.27 ENSDART00000035447
mtmr9
myotubularin related protein 9
chr8_+_23147609 0.27 ENSDART00000180284
gid8a
GID complex subunit 8 homolog a (S. cerevisiae)
chr13_+_31687973 0.27 ENSDART00000076479
slc38a6
solute carrier family 38, member 6
chr12_+_29240124 0.27 ENSDART00000053761
ENSDART00000130172
bms1
BMS1 ribosome biogenesis factor
chr7_-_30624435 0.26 ENSDART00000173828
rnf111
ring finger protein 111
chr13_+_18659325 0.26 ENSDART00000147905
ENSDART00000188249
ENSDART00000134740
selenou1a
selenoprotein U 1a
chr12_-_611367 0.26 ENSDART00000152286
wu:fj29h11
wu:fj29h11
chr15_-_28904371 0.26 ENSDART00000155154
eml2
echinoderm microtubule associated protein like 2
chr17_+_50127648 0.26 ENSDART00000156460
galnt16
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 16
chr13_-_9367647 0.26 ENSDART00000083362
ENSDART00000144146
si:dkey-33c12.4
si:dkey-33c12.4
chr14_+_16036139 0.26 ENSDART00000190733
prelid1a
PRELI domain containing 1a
chr3_-_39363065 0.26 ENSDART00000155894
arhgap23a
Rho GTPase activating protein 23a
chr12_-_30032188 0.26 ENSDART00000042514
atrnl1b
attractin-like 1b
chr10_-_28513861 0.25 ENSDART00000177781
bbx
bobby sox homolog (Drosophila)
chr15_-_2803313 0.25 ENSDART00000060839
tgfb1a
transforming growth factor, beta 1a
chr1_+_46405294 0.25 ENSDART00000143228
tubgcp3
tubulin, gamma complex associated protein 3
chr23_+_16774589 0.25 ENSDART00000104791
zgc:153722
zgc:153722
chr4_-_3064101 0.25 ENSDART00000135701
plekha5
pleckstrin homology domain containing, family A member 5
chr5_+_24086227 0.25 ENSDART00000051549
ENSDART00000177458
ENSDART00000135934
tp53
tumor protein p53
chr19_-_20446756 0.24 ENSDART00000140711
tbc1d5
TBC1 domain family, member 5
chr13_-_533243 0.24 ENSDART00000038315
nvl
nuclear VCP-like
chr17_+_24222190 0.24 ENSDART00000181698
ENSDART00000189411
ehbp1
EH domain binding protein 1
chr7_+_29962559 0.24 ENSDART00000075538
fbxo22
F-box protein 22
chr7_-_24204200 0.24 ENSDART00000087298
gmpr2
guanosine monophosphate reductase 2
chr10_-_6588793 0.24 ENSDART00000163788
chd1
chromodomain helicase DNA binding protein 1
chr4_-_18416566 0.24 ENSDART00000033717
cradd
CASP2 and RIPK1 domain containing adaptor with death domain
chr1_+_46404968 0.24 ENSDART00000042064
tubgcp3
tubulin, gamma complex associated protein 3
chr25_+_23358924 0.24 ENSDART00000156965
osbpl5
oxysterol binding protein-like 5
chr21_+_24536233 0.23 ENSDART00000145448
ENSDART00000109886
ENSDART00000135191
anapc13
anaphase promoting complex subunit 13
chr20_-_31238313 0.23 ENSDART00000028471
hpcal1
hippocalcin-like 1
chr18_-_21725805 0.23 ENSDART00000182185
fan1
FANCD2/FANCI-associated nuclease 1
chr18_+_20560616 0.23 ENSDART00000136710
ENSDART00000151974
ENSDART00000121699
ENSDART00000040074
wee2
WEE1 homolog 2 (S. pombe)
chr11_-_22361306 0.23 ENSDART00000180688
ENSDART00000182200
ENSDART00000006580
tfeb
transcription factor EB
chr11_+_30636351 0.22 ENSDART00000087909
tmem246
transmembrane protein 246
chr7_-_28641522 0.22 ENSDART00000182071
slc7a6
solute carrier family 7 (amino acid transporter light chain, y+L system), member 6
chr19_-_24136233 0.22 ENSDART00000143365
thap7
THAP domain containing 7
chr10_-_22845485 0.22 ENSDART00000079454
vamp2
vesicle-associated membrane protein 2
chr18_-_21725638 0.21 ENSDART00000089853
fan1
FANCD2/FANCI-associated nuclease 1
chr8_-_22326073 0.21 ENSDART00000084965
cep104
centrosomal protein 104
chr13_-_48431766 0.21 ENSDART00000159688
ENSDART00000171765
fbxo11a
F-box protein 11a
chr24_+_41281265 0.21 ENSDART00000156920
ENSDART00000155151
nub1
negative regulator of ubiquitin-like proteins 1
chr4_-_28353538 0.21 ENSDART00000064219
trmu
tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
chr7_-_40122139 0.21 ENSDART00000173982
si:ch73-174h16.5
si:ch73-174h16.5
chr21_+_33503835 0.20 ENSDART00000125658
clint1b
clathrin interactor 1b
chr23_-_36670369 0.20 ENSDART00000006881
zbtb39
zinc finger and BTB domain containing 39
chr1_+_49878000 0.20 ENSDART00000047876
lef1
lymphoid enhancer-binding factor 1
chr22_+_1868983 0.20 ENSDART00000160135
si:dkey-15h8.17
si:dkey-15h8.17
chr22_+_28818291 0.20 ENSDART00000136032
tp53bp2b
tumor protein p53 binding protein, 2b
chr17_-_13070602 0.20 ENSDART00000188311
ENSDART00000193428
CU469462.1

chr7_+_10562118 0.20 ENSDART00000185188
ENSDART00000168801
zfand6
zinc finger, AN1-type domain 6
chr6_-_8392104 0.20 ENSDART00000081561
ENSDART00000181178
ilf3a
interleukin enhancer binding factor 3a
chr17_+_16423721 0.20 ENSDART00000064233
efcab11
EF-hand calcium binding domain 11
chr2_+_43204919 0.19 ENSDART00000160077
ENSDART00000018729
ENSDART00000129134
ENSDART00000056402
pard3ab
par-3 family cell polarity regulator alpha, b
chr21_-_7178348 0.19 ENSDART00000187467
fam69b
family with sequence similarity 69, member B
chr18_+_1837668 0.19 ENSDART00000164210
CABZ01079192.1

chr7_-_64770456 0.19 ENSDART00000192618
zdhhc21
zinc finger, DHHC-type containing 21
chr12_+_19958845 0.19 ENSDART00000193248
ercc4
excision repair cross-complementation group 4
chr8_-_9684872 0.19 ENSDART00000132158
ptpn18
protein tyrosine phosphatase, non-receptor type 18
chr17_-_5769196 0.18 ENSDART00000113885
si:dkey-100n19.2
si:dkey-100n19.2
chr19_+_42886413 0.18 ENSDART00000151298
arpp21
cAMP-regulated phosphoprotein, 21
chr3_-_39190317 0.18 ENSDART00000013167
retsat
retinol saturase (all-trans-retinol 13,14-reductase)
chr11_+_42494531 0.18 ENSDART00000067604
arf4a
ADP-ribosylation factor 4a
chr1_+_29766725 0.18 ENSDART00000054064
zc3h13
zinc finger CCCH-type containing 13
chr16_-_27138478 0.17 ENSDART00000147438
tmem245
transmembrane protein 245
chr10_-_28027490 0.17 ENSDART00000185445
ints2
integrator complex subunit 2
chr1_-_23110740 0.17 ENSDART00000171848
ENSDART00000086797
ENSDART00000189344
ENSDART00000190858
adgrl3.1
adhesion G protein-coupled receptor L3.1
chr6_-_1591002 0.17 ENSDART00000087039
zgc:123305
zgc:123305
chr23_+_32101361 0.17 ENSDART00000138849
zgc:56699
zgc:56699
chr23_+_25201077 0.17 ENSDART00000136675
si:dkey-151g10.3
si:dkey-151g10.3
chr21_-_20381481 0.16 ENSDART00000115236
atp5mea
ATP synthase membrane subunit ea
chr16_+_35905031 0.16 ENSDART00000162411
sh3d21
SH3 domain containing 21
chr25_-_31907590 0.16 ENSDART00000149707
ENSDART00000149471
eif3ja
eukaryotic translation initiation factor 3, subunit Ja
chr10_+_36662640 0.16 ENSDART00000063359
ucp2
uncoupling protein 2
chr5_-_8602937 0.16 ENSDART00000157765
rictora
RPTOR independent companion of MTOR, complex 2 a
chr6_+_54498220 0.15 ENSDART00000103282
si:ch211-233f11.5
si:ch211-233f11.5
chr14_+_29609245 0.15 ENSDART00000043058
TENM2
si:dkey-34l15.2
chr9_+_16854121 0.15 ENSDART00000110866
cln5
CLN5, intracellular trafficking protein
chr11_-_42134968 0.15 ENSDART00000187115
FP325130.1

chr2_+_55199721 0.15 ENSDART00000016143
zmp:0000000521
zmp:0000000521
chr17_+_51520073 0.15 ENSDART00000189646
ENSDART00000170951
ENSDART00000189492
pxdn
peroxidasin
chr9_-_46276626 0.15 ENSDART00000165238
hdac4
histone deacetylase 4
chr24_-_33284945 0.14 ENSDART00000155429
ENSDART00000112845
zgc:195173
zgc:195173
chr14_+_6954579 0.14 ENSDART00000060998
nme5
NME/NM23 family member 5
chr11_-_30636163 0.14 ENSDART00000140516
zgc:153665
zgc:153665
chr25_+_20694177 0.14 ENSDART00000073648
kxd1
KxDL motif containing 1
chr5_-_20678300 0.14 ENSDART00000088639
wscd2
WSC domain containing 2
chr16_+_28764017 0.14 ENSDART00000122433
trim33l
tripartite motif containing 33, like
chr1_-_44704261 0.14 ENSDART00000133210
si:dkey-28b4.8
si:dkey-28b4.8
chr25_-_7686201 0.14 ENSDART00000157267
ENSDART00000155094
si:ch211-286c4.6
si:ch211-286c4.6
chr2_+_24867534 0.14 ENSDART00000158050
rab3aa
RAB3A, member RAS oncogene family, a
chr13_+_6189203 0.13 ENSDART00000109665
ppm1g
protein phosphatase, Mg2+/Mn2+ dependent, 1G
chr9_+_21146862 0.13 ENSDART00000136365
hao2
hydroxyacid oxidase 2 (long chain)
chr16_+_25074029 0.13 ENSDART00000155465
si:dkeyp-84f3.9
si:dkeyp-84f3.9
chr6_+_6780873 0.13 ENSDART00000011865
sec23b
Sec23 homolog B, COPII coat complex component
chr2_-_26596794 0.13 ENSDART00000134685
ENSDART00000056787
zgc:113691
zgc:113691
chr6_-_12314475 0.13 ENSDART00000156898
ENSDART00000157058
si:dkey-276j7.1
si:dkey-276j7.1
chr14_-_25956804 0.13 ENSDART00000135627
ENSDART00000146022
ENSDART00000039660
sparc
secreted protein, acidic, cysteine-rich (osteonectin)
chr4_+_25693463 0.12 ENSDART00000132864
acot18
acyl-CoA thioesterase 18
chr7_+_23495986 0.12 ENSDART00000190739
ENSDART00000115299
ENSDART00000101423
ENSDART00000142401
zgc:109889
zgc:109889
chr5_-_33769211 0.12 ENSDART00000133504
dab2ipb
DAB2 interacting protein b
chr21_-_39628771 0.12 ENSDART00000183995
aldocb
aldolase C, fructose-bisphosphate, b
chr5_-_69314495 0.12 ENSDART00000182335
smtnb
smoothelin b
chr16_+_28994709 0.12 ENSDART00000088023
gon4l
gon-4-like (C. elegans)
chr5_+_59278193 0.12 ENSDART00000160025
rasa4
RAS p21 protein activator 4
chr18_+_31117323 0.12 ENSDART00000059893
tcf25
transcription factor 25 (basic helix-loop-helix)
chr5_-_54790923 0.12 ENSDART00000176835
pik3r1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr22_-_11493236 0.12 ENSDART00000002691
tspan7b
tetraspanin 7b
chr18_+_619619 0.12 ENSDART00000159846
prtga
protogenin homolog a (Gallus gallus)
chr24_+_26997798 0.11 ENSDART00000089506
larp4b
La ribonucleoprotein domain family, member 4B
chr13_-_45201300 0.11 ENSDART00000074750
ENSDART00000180265
runx3
runt-related transcription factor 3
chr20_+_28803977 0.11 ENSDART00000153351
ENSDART00000038149
fntb
farnesyltransferase, CAAX box, beta
chr18_+_31117136 0.11 ENSDART00000138403
tcf25
transcription factor 25 (basic helix-loop-helix)
chr7_-_32020100 0.11 ENSDART00000185433
kif18a
kinesin family member 18A
chr1_-_656693 0.11 ENSDART00000170483
ENSDART00000166786
appa
amyloid beta (A4) precursor protein a
chr3_+_18795570 0.10 ENSDART00000042368
fahd1
fumarylacetoacetate hydrolase domain containing 1
chr20_+_32224405 0.10 ENSDART00000062993
ENSDART00000147448
sesn1
sestrin 1
chr9_-_32813177 0.10 ENSDART00000012694
mxc
myxovirus (influenza virus) resistance C
chr1_-_18772241 0.10 ENSDART00000147645
ENSDART00000133194
ENSDART00000147525
ENSDART00000191493
tbc1d1
TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
chr25_+_19485198 0.10 ENSDART00000156730
glsl
glutaminase like
chr25_-_21894706 0.10 ENSDART00000189158
fbxo31
F-box protein 31
chr8_+_10339869 0.10 ENSDART00000132253
tbc1d22b
TBC1 domain family, member 22B
chr14_+_36246726 0.10 ENSDART00000105602
elovl6
ELOVL fatty acid elongase 6
chr20_-_48898371 0.10 ENSDART00000170617
xrn2
5'-3' exoribonuclease 2
chr4_+_9030609 0.10 ENSDART00000154399
aldh1l2
aldehyde dehydrogenase 1 family, member L2
chr6_-_43092175 0.10 ENSDART00000084389
lrrn1
leucine rich repeat neuronal 1
chr7_-_35314347 0.10 ENSDART00000005053
slc12a4
solute carrier family 12 (potassium/chloride transporter), member 4

Network of associatons between targets according to the STRING database.

First level regulatory network of sox17

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0070900 mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.1 0.3 GO:1905072 cardiac jelly development(GO:1905072)
0.1 0.2 GO:1901216 regulation of transposition, RNA-mediated(GO:0010525) negative regulation of transposition, RNA-mediated(GO:0010526) transposition, RNA-mediated(GO:0032197) positive regulation of neuron apoptotic process(GO:0043525) positive regulation of neuron death(GO:1901216)
0.1 0.2 GO:0051973 positive regulation of telomerase activity(GO:0051973)
0.1 0.3 GO:0061181 regulation of chondrocyte development(GO:0061181)
0.1 0.4 GO:0051659 maintenance of mitochondrion location(GO:0051659)
0.1 0.5 GO:0090024 negative regulation of leukocyte chemotaxis(GO:0002689) negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of neutrophil chemotaxis(GO:0090024) negative regulation of neutrophil migration(GO:1902623)
0.1 0.2 GO:1901255 nucleotide-excision repair involved in interstrand cross-link repair(GO:1901255)
0.1 0.2 GO:0060631 regulation of meiosis I(GO:0060631)
0.1 0.2 GO:2000058 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787) regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000058)
0.0 0.5 GO:0035283 central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0 0.4 GO:0033683 nucleotide-excision repair, DNA incision(GO:0033683)
0.0 0.2 GO:0051660 establishment of centrosome localization(GO:0051660)
0.0 0.1 GO:1902176 regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902175) negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902176)
0.0 0.3 GO:0061298 retina vasculature development in camera-type eye(GO:0061298)
0.0 0.1 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.0 0.3 GO:0060251 regulation of glial cell proliferation(GO:0060251)
0.0 0.3 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.3 GO:0035475 angioblast cell migration involved in selective angioblast sprouting(GO:0035475)
0.0 0.2 GO:0060784 regulation of cell proliferation involved in tissue homeostasis(GO:0060784)
0.0 0.9 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.3 GO:0021588 cerebellum formation(GO:0021588)
0.0 0.1 GO:0090299 regulation of neural crest formation(GO:0090299)
0.0 0.3 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.0 0.1 GO:0009258 10-formyltetrahydrofolate metabolic process(GO:0009256) 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
0.0 0.2 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.3 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.0 0.2 GO:0080009 mRNA methylation(GO:0080009)
0.0 0.1 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.3 GO:0006868 glutamine transport(GO:0006868)
0.0 0.2 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.0 0.2 GO:0035677 posterior lateral line neuromast hair cell development(GO:0035677)
0.0 0.6 GO:0048263 determination of dorsal identity(GO:0048263)
0.0 0.3 GO:0048696 collateral sprouting in absence of injury(GO:0048669) regulation of collateral sprouting in absence of injury(GO:0048696)
0.0 0.1 GO:0038093 Fc receptor signaling pathway(GO:0038093)
0.0 0.3 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.0 0.2 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.5 GO:0007020 microtubule nucleation(GO:0007020)
0.0 0.1 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.0 0.1 GO:0014045 establishment of endothelial blood-brain barrier(GO:0014045)
0.0 0.2 GO:1990845 adaptive thermogenesis(GO:1990845)
0.0 0.3 GO:0000479 endonucleolytic cleavage involved in rRNA processing(GO:0000478) endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479)
0.0 0.2 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.0 0.1 GO:0030220 platelet formation(GO:0030220) platelet morphogenesis(GO:0036344)
0.0 0.3 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.0 0.1 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.1 GO:0035989 tendon development(GO:0035989)
0.0 0.0 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.1 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948) reelin-mediated signaling pathway(GO:0038026)
0.0 0.1 GO:0071233 response to leucine(GO:0043201) cellular response to leucine(GO:0071233) regulation of response to reactive oxygen species(GO:1901031)
0.0 0.2 GO:0035493 SNARE complex assembly(GO:0035493)
0.0 0.2 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.0 GO:0048785 hatching gland development(GO:0048785)
0.0 0.1 GO:0006543 glutamate biosynthetic process(GO:0006537) glutamine catabolic process(GO:0006543)
0.0 0.1 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.0 0.2 GO:2000601 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.5 GO:0006406 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0 0.1 GO:0021553 olfactory nerve development(GO:0021553) olfactory nerve morphogenesis(GO:0021627) olfactory nerve formation(GO:0021628)
0.0 0.2 GO:0022010 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.0 0.3 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.3 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 0.2 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.1 GO:0043551 regulation of lipid kinase activity(GO:0043550) regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.0 0.2 GO:2000651 positive regulation of sodium ion transport(GO:0010765) positive regulation of sodium ion transmembrane transport(GO:1902307) regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288) positive regulation of sodium ion transmembrane transporter activity(GO:2000651)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.1 0.5 GO:0070319 Golgi to plasma membrane transport vesicle(GO:0070319)
0.1 0.5 GO:0070390 transcription export complex 2(GO:0070390)
0.1 0.4 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.1 0.3 GO:0046695 SLIK (SAGA-like) complex(GO:0046695)
0.1 0.2 GO:1902560 GMP reductase complex(GO:1902560)
0.1 0.3 GO:0032807 DNA ligase IV complex(GO:0032807)
0.0 0.2 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.3 GO:0035517 PR-DUB complex(GO:0035517)
0.0 0.2 GO:0045293 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.0 0.2 GO:1990071 TRAPPII protein complex(GO:1990071)
0.0 0.5 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.1 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.0 0.1 GO:0061673 mitotic spindle astral microtubule(GO:0061673)
0.0 0.4 GO:0005903 brush border(GO:0005903)
0.0 0.3 GO:0036038 MKS complex(GO:0036038)
0.0 0.1 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.0 0.1 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.1 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.0 1.4 GO:0030027 lamellipodium(GO:0030027)
0.0 0.2 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.8 GO:0035097 histone methyltransferase complex(GO:0035097)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0070336 flap-structured DNA binding(GO:0070336)
0.1 0.5 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1 0.9 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 0.3 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 0.3 GO:0015562 protein-transmembrane transporting ATPase activity(GO:0015462) efflux transmembrane transporter activity(GO:0015562)
0.1 0.3 GO:0032184 SUMO polymer binding(GO:0032184)
0.1 0.2 GO:0003920 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.1 0.5 GO:0030274 LIM domain binding(GO:0030274)
0.1 0.3 GO:0034511 U3 snoRNA binding(GO:0034511)
0.1 0.3 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 0.2 GO:0070513 death domain binding(GO:0070513)
0.1 0.3 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.1 0.4 GO:0035173 histone kinase activity(GO:0035173)
0.1 0.4 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.2 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.9 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.1 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.2 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.0 0.5 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.2 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 0.3 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.2 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.1 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.0 0.3 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.5 GO:0017002 activin-activated receptor activity(GO:0017002)
0.0 0.1 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.0 0.1 GO:0016823 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.0 0.1 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 0.5 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.3 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.1 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0 0.3 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.4 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.3 GO:0016251 obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.0 0.2 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.2 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.1 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.1 GO:0070728 leucine binding(GO:0070728)
0.0 0.9 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0 0.3 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.1 GO:0004359 glutaminase activity(GO:0004359)
0.0 0.2 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.2 GO:0002039 p53 binding(GO:0002039)
0.0 0.3 GO:0022841 leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.0 0.1 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.2 GO:0019870 chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.0 0.1 GO:0030332 cyclin binding(GO:0030332)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.3 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.3 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.5 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 0.4 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.2 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.6 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.1 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 0.1 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.0 0.2 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.3 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.1 0.7 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.3 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.5 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.3 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.5 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.3 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.2 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.2 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.2 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 0.1 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.1 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.1 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling