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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for sox19b+sox3

Z-value: 0.66

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Transcription factors associated with sox19b+sox3

Gene Symbol Gene ID Gene Info
sox19b
ENSDARG00000040266 SRY-box transcription factor 19b
sox3
ENSDARG00000053569 SRY-box transcription factor 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
sox3dr11_v1_chr14_-_32744464_327444640.475.1e-02Click!
sox19bdr11_v1_chr7_-_26497947_264979470.361.5e-01Click!

Activity profile of sox19b+sox3 motif

Sorted Z-values of sox19b+sox3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr23_-_10175898 1.26 ENSDART00000146185
krt5
keratin 5
chr3_-_25054002 1.22 ENSDART00000086768
ep300b
E1A binding protein p300 b
chr9_+_2393764 1.15 ENSDART00000172624
chn1
chimerin 1
chr12_+_48340133 1.09 ENSDART00000152899
ENSDART00000153335
ENSDART00000054788
ddit4
DNA-damage-inducible transcript 4
chr19_-_18135724 1.07 ENSDART00000186609
cbx3a
chromobox homolog 3a (HP1 gamma homolog, Drosophila)
chr9_+_21793565 1.07 ENSDART00000134915
rev1
REV1, polymerase (DNA directed)
chr8_-_44611357 1.06 ENSDART00000063396
bag4
BCL2 associated athanogene 4
chr16_-_54919260 1.04 ENSDART00000156533
kdf1a
keratinocyte differentiation factor 1a
chr14_-_5642371 1.03 ENSDART00000183859
ENSDART00000054876
npm1b
nucleophosmin 1b
chr15_+_12429206 0.94 ENSDART00000168997
tmprss4a
transmembrane protease, serine 4a
chr7_+_38380135 0.94 ENSDART00000174005
rhpn2
rhophilin, Rho GTPase binding protein 2
chr22_-_22337382 0.90 ENSDART00000144684
si:ch211-129c21.1
si:ch211-129c21.1
chr10_+_17371356 0.89 ENSDART00000122663
sppl3
signal peptide peptidase 3
chr8_-_32385989 0.87 ENSDART00000143716
ENSDART00000098850
lipg
lipase, endothelial
chr1_-_33645967 0.86 ENSDART00000192758
cldng
claudin g
chr16_+_30002605 0.85 ENSDART00000160555
sema6e
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6E
chr7_+_39410180 0.84 ENSDART00000168641
CT030188.1

chr6_-_41138854 0.83 ENSDART00000128723
ENSDART00000151055
ENSDART00000132484
slc6a22.1
solute carrier family 6 member 22, tandem duplicate 1
chr5_+_44846434 0.83 ENSDART00000145299
ENSDART00000136521
kank1a
KN motif and ankyrin repeat domains 1a
chr12_+_16953415 0.82 ENSDART00000020824
pank1b
pantothenate kinase 1b
chr7_+_39410393 0.81 ENSDART00000158561
ENSDART00000185173
CT030188.1

chr13_+_22675802 0.80 ENSDART00000145538
ENSDART00000143312
zgc:193505
zgc:193505
chr6_-_11362871 0.78 ENSDART00000151125
pcnt
pericentrin
chr7_-_53117131 0.77 ENSDART00000169211
ENSDART00000168890
ENSDART00000172179
ENSDART00000167882
cdh1
cadherin 1, type 1, E-cadherin (epithelial)
chr15_+_22435460 0.77 ENSDART00000031976
tmem136a
transmembrane protein 136a
chr13_-_35765028 0.76 ENSDART00000157391
erlec1
endoplasmic reticulum lectin 1
chr3_-_26191960 0.76 ENSDART00000113843
ypel3
yippee-like 3
chr20_+_23498255 0.75 ENSDART00000149922
palld
palladin, cytoskeletal associated protein
chr22_-_10541372 0.73 ENSDART00000179708
si:dkey-42i9.4
si:dkey-42i9.4
chr3_+_53156813 0.71 ENSDART00000114343
brd4
bromodomain containing 4
chr2_+_2967255 0.69 ENSDART00000167649
ENSDART00000166449
pik3r3a
phosphoinositide-3-kinase, regulatory subunit 3a (gamma)
chr11_+_13423776 0.69 ENSDART00000102553
homer3b
homer scaffolding protein 3b
chr1_+_31054915 0.68 ENSDART00000148968
itga6b
integrin, alpha 6b
chr19_+_41479990 0.67 ENSDART00000087187
ago2
argonaute RISC catalytic component 2
chr4_+_26056548 0.66 ENSDART00000171204
SCYL2
si:ch211-244b2.1
chr23_-_27822920 0.66 ENSDART00000023094
acvr1ba
activin A receptor type 1Ba
chr3_+_19245804 0.66 ENSDART00000134514
smarca4a
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4a
chr8_+_23356264 0.65 ENSDART00000145062
dnmt3ba
DNA (cytosine-5-)-methyltransferase 3 beta, duplicate a
chr2_+_15048410 0.65 ENSDART00000058484
cnn3b
calponin 3, acidic b
chr3_-_31258459 0.64 ENSDART00000177928
LO017965.1

chr7_+_41812817 0.63 ENSDART00000174165
orc6
origin recognition complex, subunit 6
chr7_-_32629458 0.63 ENSDART00000001376
arl14ep
ADP-ribosylation factor-like 14 effector protein
chr15_-_16076399 0.62 ENSDART00000135658
ENSDART00000133755
ENSDART00000080413
srsf1a
serine/arginine-rich splicing factor 1a
chr22_+_17531214 0.61 ENSDART00000161174
ENSDART00000088356
hnrnpm
heterogeneous nuclear ribonucleoprotein M
chr17_+_25849332 0.61 ENSDART00000191994
acss1
acyl-CoA synthetase short chain family member 1
chr2_-_21167652 0.61 ENSDART00000185792
bmi1b
bmi1 polycomb ring finger oncogene 1b
chr13_-_36761379 0.59 ENSDART00000131534
ENSDART00000029824
map4k5
mitogen-activated protein kinase kinase kinase kinase 5
chr7_+_41812636 0.59 ENSDART00000174333
orc6
origin recognition complex, subunit 6
chr5_-_56964547 0.59 ENSDART00000074400
tia1
TIA1 cytotoxic granule-associated RNA binding protein
chr24_-_24724233 0.59 ENSDART00000127044
ENSDART00000012399
armc1
armadillo repeat containing 1
chr9_+_4378153 0.58 ENSDART00000191264
ENSDART00000182384
kalrna
kalirin RhoGEF kinase a
chr6_+_58280936 0.58 ENSDART00000155244
ralgapb
Ral GTPase activating protein, beta subunit (non-catalytic)
chr4_+_3438510 0.58 ENSDART00000155320
atxn7l1
ataxin 7-like 1
chr23_+_36308428 0.58 ENSDART00000134607
hnrnpa1b
heterogeneous nuclear ribonucleoprotein A1b
chr2_+_26237322 0.57 ENSDART00000030520
palm1b
paralemmin 1b
chr22_+_15960514 0.57 ENSDART00000181617
stil
scl/tal1 interrupting locus
chr5_-_28149767 0.57 ENSDART00000051515
zgc:110329
zgc:110329
chr3_+_26244353 0.57 ENSDART00000103733
atad5a
ATPase family, AAA domain containing 5a
chr2_+_38025260 0.57 ENSDART00000075905
hnrnpc
heterogeneous nuclear ribonucleoprotein C
chr20_+_6533260 0.57 ENSDART00000135005
ENSDART00000166356
si:ch211-191a24.4
si:ch211-191a24.4
chr21_+_34119759 0.56 ENSDART00000024750
ENSDART00000128242
hmgb3b
high mobility group box 3b
chr1_+_39995008 0.56 ENSDART00000166251
aip
aryl hydrocarbon receptor interacting protein
chr13_-_45022527 0.56 ENSDART00000159021
khdrbs1a
KH domain containing, RNA binding, signal transduction associated 1a
chr18_+_45571378 0.56 ENSDART00000077251
kifc3
kinesin family member C3
chr15_-_5901514 0.55 ENSDART00000155252
si:ch73-281n10.2
si:ch73-281n10.2
chr13_+_33368140 0.55 ENSDART00000033848
brf1a
BRF1, RNA polymerase III transcription initiation factor a
chr15_-_1835189 0.55 ENSDART00000154369
taf15
TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr18_-_7032227 0.55 ENSDART00000127138
calub
calumenin b
chr12_-_10508952 0.55 ENSDART00000152806
zgc:152977
zgc:152977
chr13_-_17860307 0.55 ENSDART00000135920
ENSDART00000054579
march8
membrane-associated ring finger (C3HC4) 8
chr1_+_49878000 0.55 ENSDART00000047876
lef1
lymphoid enhancer-binding factor 1
chr19_-_23249822 0.54 ENSDART00000140665
grb10a
growth factor receptor-bound protein 10a
chr1_+_44173245 0.54 ENSDART00000159450
ENSDART00000106048
ENSDART00000157763
ctnnd1
catenin (cadherin-associated protein), delta 1
chr22_-_4439311 0.54 ENSDART00000169317
uhrf1
ubiquitin-like with PHD and ring finger domains 1
chr25_-_12902242 0.53 ENSDART00000164733
sept15
septin 15
chr10_+_2842923 0.53 ENSDART00000181895
ykt6
YKT6 v-SNARE homolog (S. cerevisiae)
chr8_-_9570511 0.53 ENSDART00000044000
plxna3
plexin A3
chr22_-_5171362 0.53 ENSDART00000124889
tnfaip8l1
tumor necrosis factor, alpha-induced protein 8-like 1
chr5_+_39099380 0.52 ENSDART00000166657
bmp2k
BMP2 inducible kinase
chr22_+_21618121 0.52 ENSDART00000133939
tle2a
transducin like enhancer of split 2a
chr22_+_15960005 0.52 ENSDART00000033617
stil
scl/tal1 interrupting locus
chr5_+_40835601 0.52 ENSDART00000147767
si:dkey-3h3.3
si:dkey-3h3.3
chr1_-_54972170 0.52 ENSDART00000150548
ENSDART00000038330
khsrp
KH-type splicing regulatory protein
chr13_-_45022301 0.52 ENSDART00000183589
ENSDART00000125633
ENSDART00000074787
khdrbs1a
KH domain containing, RNA binding, signal transduction associated 1a
chr21_-_4849029 0.52 ENSDART00000168930
ENSDART00000151019
notch1a
notch 1a
chr24_-_31194847 0.52 ENSDART00000158808
cnn3a
calponin 3, acidic a
chr23_-_10745288 0.51 ENSDART00000140745
ENSDART00000013768
eif4e3
eukaryotic translation initiation factor 4E family member 3
chr1_+_16574312 0.51 ENSDART00000187067
mtus1b
microtubule associated tumor suppressor 1b
chr9_-_30220818 0.51 ENSDART00000140929
si:dkey-100n23.3
si:dkey-100n23.3
chr24_+_32525146 0.50 ENSDART00000132417
ENSDART00000110185
yme1l1a
YME1-like 1a
chr2_-_37134169 0.50 ENSDART00000146123
ENSDART00000146533
ENSDART00000040427
elavl1a
ELAV like RNA binding protein 1a
chr2_-_23390779 0.50 ENSDART00000020136
ivns1abpb
influenza virus NS1A binding protein b
chr20_+_26940178 0.50 ENSDART00000190888
cdca4
cell division cycle associated 4
chr21_-_4793686 0.50 ENSDART00000158232
notch1a
notch 1a
chr2_+_24638367 0.50 ENSDART00000088346
mast3a
microtubule associated serine/threonine kinase 3a
chr23_+_36308717 0.49 ENSDART00000131711
hnrnpa1b
heterogeneous nuclear ribonucleoprotein A1b
chr14_+_16036139 0.49 ENSDART00000190733
prelid1a
PRELI domain containing 1a
chr21_-_30082414 0.49 ENSDART00000157307
ENSDART00000155188
ccnjl
cyclin J-like
chr12_+_30788912 0.49 ENSDART00000160422
aldh18a1
aldehyde dehydrogenase 18 family, member A1
chr23_+_9268083 0.49 ENSDART00000055054
acss2
acyl-CoA synthetase short chain family member 2
chr2_+_26240339 0.49 ENSDART00000191006
palm1b
paralemmin 1b
chr4_-_10835620 0.49 ENSDART00000150739
ppfibp1a
PTPRF interacting protein, binding protein 1a (liprin beta 1)
chr20_+_26939742 0.49 ENSDART00000138369
ENSDART00000062061
ENSDART00000152992
cdca4
cell division cycle associated 4
chr2_-_19234329 0.49 ENSDART00000161106
ENSDART00000160060
ENSDART00000174552
cdc20
cell division cycle 20 homolog
chr19_-_46037835 0.49 ENSDART00000163815
nup153
nucleoporin 153
chr22_+_34784075 0.49 ENSDART00000167538
lcor
ligand dependent nuclear receptor corepressor
chr21_-_30166097 0.48 ENSDART00000130676
hbegfb
heparin-binding EGF-like growth factor b
chr22_+_2751887 0.48 ENSDART00000133652
si:dkey-20i20.11
si:dkey-20i20.11
chr2_+_26240631 0.48 ENSDART00000129895
palm1b
paralemmin 1b
chr16_+_27543545 0.48 ENSDART00000133398
si:ch211-197h24.6
si:ch211-197h24.6
chr9_-_28937880 0.47 ENSDART00000132878
epb41l5
erythrocyte membrane protein band 4.1 like 5
chr1_+_44173506 0.47 ENSDART00000170512
ctnnd1
catenin (cadherin-associated protein), delta 1
chr11_+_13424116 0.47 ENSDART00000125563
homer3b
homer scaffolding protein 3b
chr8_+_35964482 0.47 ENSDART00000129357
ENSDART00000154953
glt1d1
glycosyltransferase 1 domain containing 1
chr13_+_33368503 0.47 ENSDART00000139650
brf1a
BRF1, RNA polymerase III transcription initiation factor a
chr22_-_881080 0.46 ENSDART00000185489
cept1b
choline/ethanolamine phosphotransferase 1b
chr17_-_37474689 0.46 ENSDART00000103980
crip2
cysteine-rich protein 2
chr21_+_3166988 0.46 ENSDART00000168163
hnrnpabb
heterogeneous nuclear ribonucleoprotein A/Bb
chr14_+_6963312 0.46 ENSDART00000150050
hnrnpaba
heterogeneous nuclear ribonucleoprotein A/Ba
chr7_+_55950229 0.46 ENSDART00000082780
ACSF3
acyl-CoA synthetase family member 3
chr14_+_32918172 0.45 ENSDART00000182867
lnx2b
ligand of numb-protein X 2b
chr11_-_11890001 0.45 ENSDART00000081544
wipf2a
WAS/WASL interacting protein family, member 2a
chr19_+_15443540 0.45 ENSDART00000193355
lin28a
lin-28 homolog A (C. elegans)
chr10_-_20537000 0.45 ENSDART00000064603
ENSDART00000135341
plpp5
phospholipid phosphatase 5
chr12_-_27212880 0.45 ENSDART00000002835
psme3
proteasome activator subunit 3
chr17_+_43863708 0.45 ENSDART00000133874
ENSDART00000140316
ENSDART00000142929
ENSDART00000148090
zgc:66313
zgc:66313
chr10_-_36633882 0.45 ENSDART00000077161
ENSDART00000137688
rsf1b.1
rsf1b.1
remodeling and spacing factor 1b, tandem duplicate 1
remodeling and spacing factor 1b, tandem duplicate 1
chr14_+_50937757 0.45 ENSDART00000163865
rnf44
ring finger protein 44
chr6_+_54576520 0.45 ENSDART00000093199
ENSDART00000127519
ENSDART00000157142
tead3b
TEA domain family member 3 b
chr18_+_6638974 0.45 ENSDART00000162398
c2cd5
C2 calcium-dependent domain containing 5
chr2_-_26596794 0.45 ENSDART00000134685
ENSDART00000056787
zgc:113691
zgc:113691
chr17_-_7028418 0.45 ENSDART00000188305
ENSDART00000187895
sash1b
SAM and SH3 domain containing 1b
chr6_-_9676108 0.45 ENSDART00000169915
nop58
NOP58 ribonucleoprotein homolog (yeast)
chr24_-_19719240 0.44 ENSDART00000135405
csrnp1b
cysteine-serine-rich nuclear protein 1b
chr12_-_27212596 0.44 ENSDART00000153101
psme3
proteasome activator subunit 3
chr11_-_26832685 0.44 ENSDART00000153519
iqsec1b
IQ motif and Sec7 domain 1b
chr9_-_14273652 0.44 ENSDART00000135458
abcb6b
ATP-binding cassette, sub-family B (MDR/TAP), member 6b
chr23_-_36670369 0.44 ENSDART00000006881
zbtb39
zinc finger and BTB domain containing 39
chr5_-_22600881 0.44 ENSDART00000176442
nono
non-POU domain containing, octamer-binding
chr12_+_2995887 0.44 ENSDART00000189499
ENSDART00000182597
ENSDART00000184918
ENSDART00000182292
lrrc45
leucine rich repeat containing 45
chr9_-_13963078 0.44 ENSDART00000193398
ENSDART00000061156
raph1a
Ras association (RalGDS/AF-6) and pleckstrin homology domains 1a
chr24_-_34680956 0.44 ENSDART00000171009
ctnna1
catenin (cadherin-associated protein), alpha 1
chr2_-_9971609 0.43 ENSDART00000137924
ENSDART00000048655
ENSDART00000131613
zgc:55943
zgc:55943
chr3_+_29082267 0.43 ENSDART00000145615
cacna1i
calcium channel, voltage-dependent, T type, alpha 1I subunit
chr9_-_7213772 0.43 ENSDART00000174720
ENSDART00000092435
mgat4a
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr18_-_38270430 0.43 ENSDART00000139519
caprin1b
cell cycle associated protein 1b
chr18_+_8912710 0.43 ENSDART00000142866
tmem243a
transmembrane protein 243, mitochondrial a
chr21_+_12056934 0.43 ENSDART00000125380
zgc:162344
zgc:162344
chr9_-_16140860 0.43 ENSDART00000142974
myo1b
myosin IB
chr10_-_25628555 0.43 ENSDART00000143978
tiam1a
T cell lymphoma invasion and metastasis 1a
chr14_-_26392146 0.43 ENSDART00000037999
b4galt7
xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7 (galactosyltransferase I)
chr8_-_43750062 0.42 ENSDART00000142243
ulk1a
unc-51 like autophagy activating kinase 1a
chr19_+_46113828 0.42 ENSDART00000159331
ENSDART00000161826
rbm24a
RNA binding motif protein 24a
chr7_+_24006875 0.42 ENSDART00000033755
homezb
homeobox and leucine zipper encoding b
chr10_-_2788668 0.42 ENSDART00000131749
ENSDART00000124356
ENSDART00000085031
ash2l
ash2 (absent, small, or homeotic)-like (Drosophila)
chr10_-_15879569 0.42 ENSDART00000136789
tjp2a
tight junction protein 2a (zona occludens 2)
chr7_-_24995631 0.42 ENSDART00000173955
ENSDART00000173791
rcor2
REST corepressor 2
chr14_-_24277805 0.42 ENSDART00000054243
dpf2l
D4, zinc and double PHD fingers family 2, like
chr12_+_23991639 0.42 ENSDART00000003143
psme4b
proteasome activator subunit 4b
chr2_-_7185460 0.41 ENSDART00000092078
rc3h1b
ring finger and CCCH-type domains 1b
chr1_-_54971968 0.41 ENSDART00000140016
khsrp
KH-type splicing regulatory protein
chr2_+_27330461 0.41 ENSDART00000087643
tesk2
testis-specific kinase 2
chr10_-_28028998 0.41 ENSDART00000023545
ENSDART00000143487
ints2
integrator complex subunit 2
chr12_+_5048044 0.41 ENSDART00000161548
ENSDART00000172607
kif22
kinesin family member 22
chr8_+_17869225 0.41 ENSDART00000080079
slc44a5b
solute carrier family 44, member 5b
chr23_+_30736895 0.41 ENSDART00000042944
asxl1
additional sex combs like transcriptional regulator 1
chr17_+_26803470 0.40 ENSDART00000023470
pgrmc2
progesterone receptor membrane component 2
chr2_+_32846602 0.40 ENSDART00000056649
tmem53
transmembrane protein 53
chr7_+_16348835 0.40 ENSDART00000002449
mpped2a
metallophosphoesterase domain containing 2a
chr13_+_39277178 0.40 ENSDART00000113259
si:dkey-85a20.4
si:dkey-85a20.4
chr8_+_23658626 0.40 ENSDART00000083605
tbc1d25
TBC1 domain family, member 25
chr15_+_25439106 0.40 ENSDART00000156252
aifm4
apoptosis-inducing factor, mitochondrion-associated, 4
chr12_+_23991276 0.40 ENSDART00000153136
psme4b
proteasome activator subunit 4b
chr21_-_9914745 0.39 ENSDART00000172124
arhgap24
Rho GTPase activating protein 24
chr18_+_8912113 0.39 ENSDART00000147467
tmem243a
transmembrane protein 243, mitochondrial a
chr12_-_33354409 0.39 ENSDART00000178515
slc16a3
solute carrier family 16 (monocarboxylate transporter), member 3
chr7_+_45963767 0.39 ENSDART00000163098
pop4
POP4 homolog, ribonuclease P/MRP subunit
chr14_+_14841685 0.38 ENSDART00000158291
ENSDART00000162039
slbp
stem-loop binding protein
chr9_-_13871935 0.38 ENSDART00000146597
raph1a
Ras association (RalGDS/AF-6) and pleckstrin homology domains 1a
chr2_-_26642831 0.38 ENSDART00000132854
ENSDART00000087714
ENSDART00000132651
u2surp
U2 snRNP-associated SURP domain containing
chr9_+_35832294 0.38 ENSDART00000130549
ENSDART00000122169
si:dkey-67c22.2
si:dkey-67c22.2
chr8_-_410199 0.38 ENSDART00000091177
ENSDART00000122979
ENSDART00000151331
ENSDART00000151155
trim36
tripartite motif containing 36
chr4_+_9178913 0.38 ENSDART00000168558
nfyba
nuclear transcription factor Y, beta a
chr5_+_25762271 0.38 ENSDART00000181323
tmem2
transmembrane protein 2
chr22_-_18546241 0.38 ENSDART00000105404
ENSDART00000105405
cirbpb
cold inducible RNA binding protein b
chr15_+_40079468 0.37 ENSDART00000154947
ngef
neuronal guanine nucleotide exchange factor
chr15_-_17138640 0.37 ENSDART00000080777
mrpl28
mitochondrial ribosomal protein L28
chr5_-_54712159 0.37 ENSDART00000149207
ccnb1
cyclin B1
chr18_-_12327426 0.37 ENSDART00000136992
ENSDART00000114024
fam107b
family with sequence similarity 107, member B
chr6_-_12172424 0.37 ENSDART00000109344
tanc1a
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1a
chr2_-_38206331 0.37 ENSDART00000136082
acin1a
apoptotic chromatin condensation inducer 1a
chr2_-_15040345 0.37 ENSDART00000109657
si:dkey-10f21.4
si:dkey-10f21.4
chr23_+_24989387 0.37 ENSDART00000172299
ENSDART00000145307
arhgap4a
Rho GTPase activating protein 4a
chr13_-_33700461 0.37 ENSDART00000160520
mad2l1bp
MAD2L1 binding protein
chr17_+_24597001 0.37 ENSDART00000191834
rlf
rearranged L-myc fusion
chr3_+_28576173 0.37 ENSDART00000151189
sept12
septin 12
chr24_-_22103585 0.37 ENSDART00000000070
dap
death-associated protein
chr2_-_24069331 0.36 ENSDART00000156972
ENSDART00000181691
ENSDART00000157041
slc12a7a
solute carrier family 12 (potassium/chloride transporter), member 7a
chr23_+_38171186 0.36 ENSDART00000148188
zgc:112994
zgc:112994
chr15_+_39977461 0.36 ENSDART00000063786
cab39
calcium binding protein 39

Network of associatons between targets according to the STRING database.

First level regulatory network of sox19b+sox3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0021531 spinal cord radial glial cell differentiation(GO:0021531)
0.3 1.1 GO:0021557 oculomotor nerve development(GO:0021557)
0.3 1.1 GO:0070987 error-free translesion synthesis(GO:0070987)
0.2 1.0 GO:0010610 regulation of mRNA stability involved in response to stress(GO:0010610) regulation of mRNA stability involved in response to oxidative stress(GO:2000815)
0.2 0.7 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
0.2 1.0 GO:0010482 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.2 1.1 GO:0006083 acetate metabolic process(GO:0006083) acetyl-CoA biosynthetic process from acetate(GO:0019427)
0.2 0.9 GO:0010693 regulation of alkaline phosphatase activity(GO:0010692) negative regulation of alkaline phosphatase activity(GO:0010693)
0.2 0.9 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.2 1.2 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.2 1.0 GO:0034334 adherens junction maintenance(GO:0034334)
0.2 0.6 GO:0003228 atrial cardiac muscle tissue development(GO:0003228)
0.1 0.5 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.1 0.8 GO:0035092 spermatid nucleus differentiation(GO:0007289) sperm chromatin condensation(GO:0035092) spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.1 0.7 GO:0098795 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.1 1.1 GO:0071539 protein localization to centrosome(GO:0071539)
0.1 0.5 GO:0071675 regulation of macrophage chemotaxis(GO:0010758) positive regulation of macrophage chemotaxis(GO:0010759) mononuclear cell migration(GO:0071674) regulation of mononuclear cell migration(GO:0071675) positive regulation of lamellipodium organization(GO:1902745)
0.1 1.0 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.1 0.5 GO:0060784 regulation of cell proliferation involved in tissue homeostasis(GO:0060784)
0.1 0.3 GO:0032814 regulation of natural killer cell activation(GO:0032814) positive regulation of natural killer cell activation(GO:0032816) TRIF-dependent toll-like receptor signaling pathway(GO:0035666)
0.1 0.3 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.1 0.3 GO:0039015 spinal cord anterior/posterior patterning(GO:0021512) cell proliferation involved in pronephros development(GO:0039015) cell proliferation involved in kidney development(GO:0072111)
0.1 0.9 GO:0006465 signal peptide processing(GO:0006465)
0.1 0.9 GO:0072498 embryonic skeletal joint development(GO:0072498)
0.1 0.3 GO:2000434 regulation of protein neddylation(GO:2000434)
0.1 0.4 GO:0010828 positive regulation of glucose transport(GO:0010828)
0.1 0.3 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659) negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.1 0.3 GO:1990575 mitochondrial ornithine transport(GO:0000066) mitochondrial L-ornithine transmembrane transport(GO:1990575)
0.1 0.8 GO:2000273 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) positive regulation of receptor activity(GO:2000273)
0.1 0.7 GO:0021634 optic nerve formation(GO:0021634)
0.1 0.5 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.1 0.6 GO:0030728 ovulation(GO:0030728)
0.1 0.3 GO:1904666 negative regulation of ligase activity(GO:0051352) negative regulation of ubiquitin-protein transferase activity(GO:0051444) regulation of ubiquitin protein ligase activity(GO:1904666) negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.1 0.1 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.1 0.2 GO:0034473 cerebellar Purkinje cell layer structural organization(GO:0021693) cerebellar cortex structural organization(GO:0021698) U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476) nuclear polyadenylation-dependent mRNA catabolic process(GO:0071042) polyadenylation-dependent mRNA catabolic process(GO:0071047)
0.1 0.4 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.1 0.6 GO:0006561 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.1 0.5 GO:0021744 medulla oblongata development(GO:0021550) dorsal motor nucleus of vagus nerve development(GO:0021744)
0.1 0.3 GO:0030219 megakaryocyte differentiation(GO:0030219)
0.1 1.0 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.1 0.4 GO:1900028 wound healing, spreading of epidermal cells(GO:0035313) negative regulation of ruffle assembly(GO:1900028)
0.1 0.7 GO:0001709 cell fate determination(GO:0001709)
0.1 0.3 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.1 0.5 GO:0019747 regulation of isoprenoid metabolic process(GO:0019747) regulation of vitamin metabolic process(GO:0030656) regulation of retinoic acid biosynthetic process(GO:1900052)
0.1 0.4 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.1 0.8 GO:1900077 negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.1 0.7 GO:0043550 regulation of lipid kinase activity(GO:0043550) regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.1 0.9 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.4 GO:1901096 regulation of autophagosome maturation(GO:1901096)
0.0 1.1 GO:0010390 histone monoubiquitination(GO:0010390)
0.0 0.2 GO:0060231 mesenchymal to epithelial transition(GO:0060231)
0.0 0.3 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 1.0 GO:0070897 DNA-templated transcriptional preinitiation complex assembly(GO:0070897)
0.0 0.7 GO:0051310 metaphase plate congression(GO:0051310)
0.0 0.3 GO:0003272 endocardial cushion formation(GO:0003272)
0.0 0.3 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.2 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.0 0.1 GO:1904871 positive regulation of protein localization to nucleus(GO:1900182) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
0.0 0.2 GO:0048103 neuronal stem cell division(GO:0036445) somatic stem cell division(GO:0048103)
0.0 0.4 GO:0034198 cellular response to amino acid starvation(GO:0034198)
0.0 0.5 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.2 GO:0060829 negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060829)
0.0 0.1 GO:0034154 toll-like receptor 3 signaling pathway(GO:0034138) toll-like receptor 7 signaling pathway(GO:0034154)
0.0 0.5 GO:0006285 base-excision repair, AP site formation(GO:0006285)
0.0 0.2 GO:0030220 platelet formation(GO:0030220) platelet morphogenesis(GO:0036344)
0.0 0.6 GO:0016926 protein desumoylation(GO:0016926)
0.0 1.4 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.0 0.6 GO:0008078 mesodermal cell migration(GO:0008078)
0.0 0.5 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.5 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.3 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.7 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.7 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.1 GO:0019417 sulfur oxidation(GO:0019417)
0.0 0.4 GO:0009303 rRNA transcription(GO:0009303)
0.0 0.1 GO:0032801 receptor catabolic process(GO:0032801)
0.0 0.8 GO:0006515 misfolded or incompletely synthesized protein catabolic process(GO:0006515)
0.0 0.2 GO:2000785 regulation of autophagosome assembly(GO:2000785)
0.0 0.3 GO:0050819 negative regulation of coagulation(GO:0050819)
0.0 0.3 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.1 GO:0044090 positive regulation of vacuole organization(GO:0044090)
0.0 0.7 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.2 GO:0072393 microtubule anchoring at microtubule organizing center(GO:0072393)
0.0 1.1 GO:0050821 protein stabilization(GO:0050821)
0.0 0.5 GO:0009409 response to cold(GO:0009409)
0.0 0.1 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 0.2 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.0 0.2 GO:0021628 olfactory nerve development(GO:0021553) olfactory nerve morphogenesis(GO:0021627) olfactory nerve formation(GO:0021628)
0.0 0.3 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 0.2 GO:1904825 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.0 0.2 GO:1903432 regulation of TORC1 signaling(GO:1903432) positive regulation of TORC1 signaling(GO:1904263)
0.0 0.1 GO:2000144 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 0.6 GO:0006284 base-excision repair(GO:0006284)
0.0 2.4 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.0 0.1 GO:0019388 galactose catabolic process(GO:0019388) galactose catabolic process via UDP-galactose(GO:0033499)
0.0 0.2 GO:0048569 post-embryonic organ development(GO:0048569)
0.0 0.3 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.1 GO:0071830 chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830) intermediate-density lipoprotein particle clearance(GO:0071831)
0.0 0.3 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.0 0.5 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.4 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.0 0.4 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.0 0.2 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948) reelin-mediated signaling pathway(GO:0038026)
0.0 0.1 GO:2000279 negative regulation of DNA biosynthetic process(GO:2000279)
0.0 0.2 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.0 0.2 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.5 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.3 GO:0002574 thrombocyte differentiation(GO:0002574)
0.0 0.2 GO:1902624 positive regulation of neutrophil migration(GO:1902624)
0.0 0.4 GO:0050684 regulation of mRNA processing(GO:0050684)
0.0 0.1 GO:0000730 DNA recombinase assembly(GO:0000730)
0.0 0.3 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.5 GO:0006305 DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.0 0.1 GO:0071459 protein localization to kinetochore(GO:0034501) protein localization to chromosome, centromeric region(GO:0071459)
0.0 0.3 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.1 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.0 0.2 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.5 GO:0035329 hippo signaling(GO:0035329)
0.0 0.6 GO:0006998 nuclear envelope organization(GO:0006998)
0.0 0.9 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)
0.0 0.2 GO:1903010 regulation of bone development(GO:1903010)
0.0 0.1 GO:0003232 bulbus arteriosus development(GO:0003232) negative regulation of histone methylation(GO:0031061)
0.0 1.2 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 0.4 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 0.2 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0 0.2 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.0 0.2 GO:0030316 osteoclast differentiation(GO:0030316)
0.0 0.8 GO:0099515 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.0 0.3 GO:0006278 RNA-dependent DNA biosynthetic process(GO:0006278) telomere maintenance via telomerase(GO:0007004)
0.0 0.4 GO:0030048 actin filament-based movement(GO:0030048)
0.0 1.0 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 0.1 GO:0015886 heme transport(GO:0015886) iron coordination entity transport(GO:1901678)
0.0 0.1 GO:0031269 pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.9 GO:0010950 positive regulation of endopeptidase activity(GO:0010950) positive regulation of peptidase activity(GO:0010952)
0.0 0.0 GO:0018872 arsonoacetate metabolic process(GO:0018872)
0.0 1.4 GO:0008360 regulation of cell shape(GO:0008360)
0.0 0.5 GO:0072114 pronephros morphogenesis(GO:0072114)
0.0 0.2 GO:0010996 response to auditory stimulus(GO:0010996)
0.0 0.1 GO:0055107 Golgi to secretory granule transport(GO:0055107)
0.0 0.0 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
0.0 0.1 GO:0071405 response to methanol(GO:0033986) cellular response to methanol(GO:0071405)
0.0 1.2 GO:0016573 histone acetylation(GO:0016573)
0.0 0.2 GO:0019730 antimicrobial humoral response(GO:0019730)
0.0 0.7 GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:0000288)
0.0 0.2 GO:0098887 neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887) endosome to plasma membrane protein transport(GO:0099638) neurotransmitter receptor transport, endosome to plasma membrane(GO:0099639)
0.0 0.4 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.5 GO:0045766 positive regulation of angiogenesis(GO:0045766)
0.0 0.6 GO:0016575 histone deacetylation(GO:0016575)
0.0 0.4 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.1 GO:0051601 exocyst localization(GO:0051601)
0.0 0.7 GO:0071599 otic vesicle development(GO:0071599)
0.0 0.3 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.3 GO:0070936 protein K48-linked ubiquitination(GO:0070936)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0071556 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.2 0.9 GO:0008537 proteasome activator complex(GO:0008537)
0.2 0.8 GO:1990111 spermatoproteasome complex(GO:1990111)
0.2 1.2 GO:0005845 mRNA cap binding complex(GO:0005845)
0.1 0.4 GO:0031213 RSF complex(GO:0031213)
0.1 1.0 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.1 0.4 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.1 1.3 GO:0045095 keratin filament(GO:0045095)
0.1 0.3 GO:0000941 condensed nuclear chromosome inner kinetochore(GO:0000941)
0.1 1.2 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 0.3 GO:0097189 apoptotic body(GO:0097189)
0.1 0.9 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 0.6 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.1 1.5 GO:0030057 desmosome(GO:0030057)
0.1 0.4 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.1 1.0 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.1 0.4 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1 0.2 GO:0089701 U2AF(GO:0089701)
0.1 0.2 GO:1990745 EARP complex(GO:1990745)
0.1 0.4 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.7 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.3 GO:0035517 PR-DUB complex(GO:0035517)
0.0 0.8 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.2 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 0.1 GO:0033065 Rad51C-XRCC3 complex(GO:0033065)
0.0 0.5 GO:0000792 heterochromatin(GO:0000792)
0.0 0.3 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.1 GO:0017177 glucosidase II complex(GO:0017177)
0.0 0.7 GO:0005903 brush border(GO:0005903)
0.0 0.4 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.7 GO:0032039 integrator complex(GO:0032039)
0.0 1.4 GO:0090544 BAF-type complex(GO:0090544)
0.0 0.2 GO:0043194 axon initial segment(GO:0043194)
0.0 0.3 GO:0000243 commitment complex(GO:0000243)
0.0 0.2 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.0 1.1 GO:0005940 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.2 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.6 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.5 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 0.4 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.3 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944) phosphatidylinositol 3-kinase complex, class I(GO:0097651)
0.0 0.5 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.2 GO:0019908 cyclin/CDK positive transcription elongation factor complex(GO:0008024) nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.0 0.3 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.2 GO:0000176 nuclear exosome (RNase complex)(GO:0000176) cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 2.3 GO:0016607 nuclear speck(GO:0016607)
0.0 0.3 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.1 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.0 0.5 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.3 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.6 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 1.9 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 1.2 GO:0005814 centriole(GO:0005814)
0.0 0.7 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 0.1 GO:0016586 RSC complex(GO:0016586)
0.0 0.1 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 0.1 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.5 GO:0005758 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 0.1 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.1 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.3 GO:0000145 exocyst(GO:0000145)
0.0 0.9 GO:0005871 kinesin complex(GO:0005871)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.1 GO:0071889 14-3-3 protein binding(GO:0071889)
0.2 1.2 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.2 1.1 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.2 1.7 GO:0016504 peptidase activator activity(GO:0016504)
0.2 0.7 GO:0070883 pre-miRNA binding(GO:0070883)
0.2 0.5 GO:0072590 N-acetyl-L-aspartate-L-glutamate ligase activity(GO:0072590) citrate-L-glutamate ligase activity(GO:0072591)
0.1 1.0 GO:0000995 transcription factor activity, core RNA polymerase III binding(GO:0000995)
0.1 0.4 GO:1990825 mRNA CDS binding(GO:1990715) sequence-specific mRNA binding(GO:1990825)
0.1 0.8 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 0.6 GO:0008311 double-stranded DNA exodeoxyribonuclease activity(GO:0008309) double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.1 0.9 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 0.7 GO:0016361 activin receptor activity, type I(GO:0016361)
0.1 1.1 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 0.9 GO:0035925 AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 0.5 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.1 0.5 GO:0010997 anaphase-promoting complex binding(GO:0010997) ubiquitin ligase activator activity(GO:1990757)
0.1 0.4 GO:0033204 ribonuclease P RNA binding(GO:0033204)
0.1 0.5 GO:0004307 diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307)
0.1 0.3 GO:0004394 heparan sulfate 2-O-sulfotransferase activity(GO:0004394)
0.1 0.4 GO:0070513 death domain binding(GO:0070513)
0.1 0.4 GO:0001223 transcription coactivator binding(GO:0001223)
0.1 0.4 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 0.6 GO:0035613 RNA stem-loop binding(GO:0035613)
0.1 1.5 GO:0008301 DNA binding, bending(GO:0008301)
0.1 0.9 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.1 0.7 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 0.5 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.1 0.8 GO:0043495 protein anchor(GO:0043495)
0.1 0.8 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.1 0.5 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.1 0.8 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 0.5 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.1 0.3 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.1 0.2 GO:0042806 fucose binding(GO:0042806)
0.1 1.1 GO:0008143 poly(A) binding(GO:0008143)
0.1 0.5 GO:0000700 mismatch base pair DNA N-glycosylase activity(GO:0000700) pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263)
0.1 1.1 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 0.4 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.6 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 1.1 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.4 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.6 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.5 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.3 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.5 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.1 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.0 0.2 GO:0050699 WW domain binding(GO:0050699)
0.0 0.6 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.2 GO:0004471 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.0 1.0 GO:0005112 Notch binding(GO:0005112)
0.0 0.3 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.1 GO:0003978 UDP-glucose 4-epimerase activity(GO:0003978)
0.0 0.3 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0 0.4 GO:0043047 single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.0 0.9 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.8 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.1 GO:0004373 glycogen (starch) synthase activity(GO:0004373)
0.0 0.4 GO:0000217 DNA secondary structure binding(GO:0000217)
0.0 0.4 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.5 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 2.3 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.2 GO:0004356 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.0 1.8 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.6 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.2 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.2 GO:0015616 DNA translocase activity(GO:0015616)
0.0 0.2 GO:0004477 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
0.0 0.3 GO:0035250 UDP-galactosyltransferase activity(GO:0035250)
0.0 0.1 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.1 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 0.4 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 0.4 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.3 GO:0045503 dynein light chain binding(GO:0045503)
0.0 0.2 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.6 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.8 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.2 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 3.6 GO:0042393 histone binding(GO:0042393)
0.0 0.2 GO:0005522 profilin binding(GO:0005522)
0.0 0.6 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 1.2 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 1.3 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.6 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.1 GO:0033842 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity(GO:0033842)
0.0 0.4 GO:0015379 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.0 0.5 GO:0042287 MHC protein binding(GO:0042287)
0.0 1.5 GO:0045296 cadherin binding(GO:0045296)
0.0 0.4 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.8 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.3 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.0 GO:0030792 arsenite methyltransferase activity(GO:0030791) methylarsonite methyltransferase activity(GO:0030792)
0.0 0.3 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.1 GO:0070728 leucine binding(GO:0070728)
0.0 2.4 GO:0060090 binding, bridging(GO:0060090)
0.0 0.4 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.2 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.0 0.2 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.4 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 0.2 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.1 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 0.6 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.2 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.1 1.1 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.8 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 1.6 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 1.1 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 0.3 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.4 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.2 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.6 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 1.0 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.5 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.4 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.6 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.2 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 1.1 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.3 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.6 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.3 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.2 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.4 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.8 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.1 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.0 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.7 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.3 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.3 PID TNF PATHWAY TNF receptor signaling pathway
0.0 0.4 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.8 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.1 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.4 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.2 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.2 PID CASPASE PATHWAY Caspase cascade in apoptosis

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.2 1.1 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 1.6 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.1 0.4 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.1 1.1 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.1 0.6 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 1.3 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 0.6 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.5 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.2 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.0 0.3 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 1.0 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.3 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.4 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.4 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.8 REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.0 0.6 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.3 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.4 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.1 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.4 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.8 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.4 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.3 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.3 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.0 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.3 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.0 1.3 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.4 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.4 REACTOME KINESINS Genes involved in Kinesins
0.0 1.5 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.4 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 2.2 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.1 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.1 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.3 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.1 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.2 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.1 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 1.1 REACTOME DNA REPAIR Genes involved in DNA Repair
0.0 0.0 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.0 0.1 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.3 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions