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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for sox1a+sox1b

Z-value: 0.15

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Transcription factors associated with sox1a+sox1b

Gene Symbol Gene ID Gene Info
sox1b
ENSDARG00000008131 SRY-box transcription factor 1b
sox1a
ENSDARG00000069866 SRY-box transcription factor 1a
sox1a
ENSDARG00000110682 SRY-box transcription factor 1a
sox1a
ENSDARG00000114571 SRY-box transcription factor 1a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
sox1adr11_v1_chr9_+_21722733_21722733-0.662.7e-03Click!
sox1bdr11_v1_chr1_+_46194333_46194333-0.532.3e-02Click!

Activity profile of sox1a+sox1b motif

Sorted Z-values of sox1a+sox1b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr25_+_18475032 0.27 ENSDART00000073564
tes
testis derived transcript (3 LIM domains)
chr14_+_15768942 0.24 ENSDART00000158998
ergic1
endoplasmic reticulum-golgi intermediate compartment 1
chr19_+_15440841 0.21 ENSDART00000182329
lin28a
lin-28 homolog A (C. elegans)
chr8_+_42917515 0.20 ENSDART00000021715
slc23a2
solute carrier family 23 (ascorbic acid transporter), member 2
chr25_+_418932 0.20 ENSDART00000059193
prtgb
protogenin homolog b (Gallus gallus)
chr5_+_51833305 0.19 ENSDART00000165276
ENSDART00000166443
papd4
PAP associated domain containing 4
chr16_-_44878245 0.17 ENSDART00000154391
ENSDART00000154925
ENSDART00000154697
arhgap33
Rho GTPase activating protein 33
chr23_-_24247672 0.17 ENSDART00000141552
zbtb17
zinc finger and BTB domain containing 17
chr19_+_14109348 0.16 ENSDART00000159015
zgc:175136
zgc:175136
chr7_+_31425976 0.16 ENSDART00000075400
eif3jb
eukaryotic translation initiation factor 3, subunit Jb
chr2_+_31308587 0.16 ENSDART00000027090
clul1
clusterin-like 1 (retinal)
chr2_+_36620011 0.15 ENSDART00000177428
pak2a
p21 protein (Cdc42/Rac)-activated kinase 2a
chr5_+_51833132 0.15 ENSDART00000167491
papd4
PAP associated domain containing 4
chr22_+_35131890 0.13 ENSDART00000003303
ENSDART00000130581
rnf13
ring finger protein 13
chr16_-_21047483 0.13 ENSDART00000136235
cbx3b
chromobox homolog 3b
chr5_+_30520249 0.13 ENSDART00000013431
hmbsa
hydroxymethylbilane synthase a
chr2_+_1881334 0.13 ENSDART00000161420
adgrl2b.1
adhesion G protein-coupled receptor L2b, tandem duplicate 1
chr13_+_15581270 0.13 ENSDART00000189880
ENSDART00000190067
ENSDART00000041293
mark3a
MAP/microtubule affinity-regulating kinase 3a
chr18_-_45761868 0.12 ENSDART00000025423
cstf3
cleavage stimulation factor, 3' pre-RNA, subunit 3
chr1_+_50639416 0.12 ENSDART00000141977
herc3
HECT and RLD domain containing E3 ubiquitin protein ligase 3
chr15_+_24005289 0.11 ENSDART00000088648
myo18ab
myosin XVIIIAb
chr20_+_27093042 0.11 ENSDART00000024595
ubr7
ubiquitin protein ligase E3 component n-recognin 7
chr2_-_31833347 0.11 ENSDART00000109460
nol7
nucleolar protein 7
chr11_+_16216909 0.11 ENSDART00000081035
ENSDART00000147190
slc25a26
solute carrier family 25 (S-adenosylmethionine carrier), member 26
chr7_-_18877109 0.10 ENSDART00000113593
mllt3
MLLT3, super elongation complex subunit
chr2_-_54039293 0.10 ENSDART00000166013
abhd8a
abhydrolase domain containing 8a
chr17_-_19463355 0.10 ENSDART00000045881
dicer1
dicer 1, ribonuclease type III
chr8_+_49096486 0.10 ENSDART00000192998
zgc:56525
zgc:56525
chr11_+_31324335 0.09 ENSDART00000088093
sipa1l2
signal-induced proliferation-associated 1 like 2
chr23_-_12158685 0.09 ENSDART00000135035
fam217b
family with sequence similarity 217, member B
chr16_-_21047872 0.08 ENSDART00000131582
cbx3b
chromobox homolog 3b
chr9_+_25853052 0.08 ENSDART00000127135
gtdc1
glycosyltransferase-like domain containing 1
chr16_-_30826712 0.08 ENSDART00000122474
ptk2ab
protein tyrosine kinase 2ab
chr6_-_37513133 0.08 ENSDART00000147826
jade3
jade family PHD finger 3
chr24_-_9291857 0.07 ENSDART00000149875
tgif1
TGFB-induced factor homeobox 1
chr7_+_50796422 0.07 ENSDART00000123868
dthd1
death domain containing 1
chr1_+_59328030 0.05 ENSDART00000172464
CABZ01052576.1

chr21_-_19916021 0.05 ENSDART00000065671
eri1
exoribonuclease 1
chr21_-_19915757 0.05 ENSDART00000164317
eri1
exoribonuclease 1
chr3_+_9588705 0.05 ENSDART00000172543
ENSDART00000104875
trap1
TNF receptor-associated protein 1
chr12_+_26512569 0.04 ENSDART00000066264
chad
chondroadherin
chr7_+_28960518 0.04 ENSDART00000182903
ENSDART00000188250
ENSDART00000191830
dok4
docking protein 4
chr25_-_19661198 0.04 ENSDART00000149641
atp2b1b
ATPase plasma membrane Ca2+ transporting 1b
chr18_+_33464345 0.02 ENSDART00000059447
v2rh9
vomeronasal 2 receptor, h9
chr4_-_9664995 0.02 ENSDART00000180105
ENSDART00000029084
dmtf1
cyclin D binding myb-like transcription factor 1
chr22_+_9994833 0.02 ENSDART00000172696
ENSDART00000192101
BX324216.1

chr4_-_9665267 0.02 ENSDART00000150318
dmtf1
cyclin D binding myb-like transcription factor 1
chr22_-_8931093 0.01 ENSDART00000181813
FO393424.3

chr14_+_6429399 0.01 ENSDART00000149783
ENSDART00000148461
abca1b
ATP-binding cassette, sub-family A (ABC1), member 1B
chr9_-_6624663 0.01 ENSDART00000092537
GPR45
si:dkeyp-118h3.5
chr2_+_48687528 0.01 ENSDART00000158312
si:dkey-53k12.1
si:dkey-53k12.1
chr19_+_20177887 0.01 ENSDART00000008595
tra2a
transformer 2 alpha homolog
chr3_+_4213864 0.01 ENSDART00000059613
si:dkeyp-52c3.5
si:dkeyp-52c3.5
chr10_-_36236610 0.01 ENSDART00000159381
or109-3
odorant receptor, family D, subfamily 109, member 3
chr14_-_17072736 0.00 ENSDART00000106333
phox2bb
paired-like homeobox 2bb
chr10_+_25726694 0.00 ENSDART00000140308
ugt5d1
UDP glucuronosyltransferase 5 family, polypeptide D1
chr7_+_57677120 0.00 ENSDART00000110623
arsj
arylsulfatase family, member J
chr7_-_47148440 0.00 ENSDART00000185435
ENSDART00000189719
BX005073.3

chr2_-_28420415 0.00 ENSDART00000183857
CABZ01056051.1

chr1_+_25732715 0.00 ENSDART00000140172
npy2r
neuropeptide Y receptor Y2
chr15_-_2493771 0.00 ENSDART00000184906
neu4
sialidase 4

Network of associatons between targets according to the STRING database.

First level regulatory network of sox1a+sox1b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0015882 L-ascorbic acid transport(GO:0015882) L-ascorbic acid metabolic process(GO:0019852)
0.0 0.1 GO:0030423 targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.0 0.1 GO:0018160 peptidyl-pyrromethane cofactor linkage(GO:0018160)
0.0 0.1 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0070578 RISC-loading complex(GO:0070578)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0032296 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296) pre-miRNA binding(GO:0070883)
0.0 0.1 GO:0004418 hydroxymethylbilane synthase activity(GO:0004418)
0.0 0.1 GO:0051185 coenzyme transporter activity(GO:0051185)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis