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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for sox6

Z-value: 1.22

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Transcription factors associated with sox6

Gene Symbol Gene ID Gene Info
sox6
ENSDARG00000015536 SRY-box transcription factor 6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
sox6dr11_v1_chr7_+_27250186_27250186-0.983.5e-12Click!

Activity profile of sox6 motif

Sorted Z-values of sox6 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_2578026 6.46 ENSDART00000065821
zp3.2
zona pellucida glycoprotein 3, tandem duplicate 2
chr12_+_48340133 4.90 ENSDART00000152899
ENSDART00000153335
ENSDART00000054788
ddit4
DNA-damage-inducible transcript 4
chr17_-_2590222 4.56 ENSDART00000185711
CR759892.1

chr1_-_33645967 3.94 ENSDART00000192758
cldng
claudin g
chr22_-_10541372 3.83 ENSDART00000179708
si:dkey-42i9.4
si:dkey-42i9.4
chr12_-_33354409 3.79 ENSDART00000178515
slc16a3
solute carrier family 16 (monocarboxylate transporter), member 3
chr19_-_27588842 3.56 ENSDART00000121643
si:dkeyp-46h3.2
si:dkeyp-46h3.2
chr17_-_2573021 3.45 ENSDART00000074181
zp3.2
zona pellucida glycoprotein 3, tandem duplicate 2
chr24_-_24724233 3.38 ENSDART00000127044
ENSDART00000012399
armc1
armadillo repeat containing 1
chr10_+_15608326 3.08 ENSDART00000188770
zfand5b
zinc finger, AN1-type domain 5b
chr24_-_19719240 2.76 ENSDART00000135405
csrnp1b
cysteine-serine-rich nuclear protein 1b
chr16_-_54919260 2.52 ENSDART00000156533
kdf1a
keratinocyte differentiation factor 1a
chr10_+_2842923 2.41 ENSDART00000181895
ykt6
YKT6 v-SNARE homolog (S. cerevisiae)
chr14_-_41478265 2.22 ENSDART00000149886
ENSDART00000016002
tspan7
tetraspanin 7
chr2_+_26240631 2.21 ENSDART00000129895
palm1b
paralemmin 1b
chr2_+_32846602 2.21 ENSDART00000056649
tmem53
transmembrane protein 53
chr13_+_33368503 2.18 ENSDART00000139650
brf1a
BRF1, RNA polymerase III transcription initiation factor a
chr15_+_12429206 2.08 ENSDART00000168997
tmprss4a
transmembrane protease, serine 4a
chr22_-_10541712 2.07 ENSDART00000013933
si:dkey-42i9.4
si:dkey-42i9.4
chr13_+_46941930 1.99 ENSDART00000056962
fbxo5
F-box protein 5
chr1_-_354115 1.92 ENSDART00000141590
ENSDART00000098627
pros1
protein S
chr19_-_23249822 1.90 ENSDART00000140665
grb10a
growth factor receptor-bound protein 10a
chr13_+_42309688 1.85 ENSDART00000158367
ide
insulin-degrading enzyme
chr21_+_34119759 1.83 ENSDART00000024750
ENSDART00000128242
hmgb3b
high mobility group box 3b
chr5_-_28149767 1.69 ENSDART00000051515
zgc:110329
zgc:110329
chr7_+_22801465 1.67 ENSDART00000052862
ENSDART00000173633
rbm4.1
RNA binding motif protein 4.1
chr1_+_39995008 1.66 ENSDART00000166251
aip
aryl hydrocarbon receptor interacting protein
chr24_-_21343982 1.60 ENSDART00000012653
spice1
spindle and centriole associated protein 1
chr9_+_21793565 1.56 ENSDART00000134915
rev1
REV1, polymerase (DNA directed)
chr13_-_33700461 1.56 ENSDART00000160520
mad2l1bp
MAD2L1 binding protein
chr22_-_37565348 1.51 ENSDART00000149482
ENSDART00000104478
fxr1
fragile X mental retardation, autosomal homolog 1
chr3_+_49074008 1.47 ENSDART00000168864
zgc:112146
zgc:112146
chr3_-_25054002 1.41 ENSDART00000086768
ep300b
E1A binding protein p300 b
chr9_+_21795917 1.34 ENSDART00000169069
rev1
REV1, polymerase (DNA directed)
chr3_+_53156813 1.31 ENSDART00000114343
brd4
bromodomain containing 4
chr2_+_49457626 1.26 ENSDART00000129967
sh3gl1a
SH3-domain GRB2-like 1a
chr7_-_24520866 1.25 ENSDART00000077039
faah2b
fatty acid amide hydrolase 2b
chr3_+_29641181 1.25 ENSDART00000151517
eif3d
eukaryotic translation initiation factor 3, subunit D
chr19_-_27339844 1.25 ENSDART00000052358
ENSDART00000148238
ENSDART00000147661
ENSDART00000137346
znrd1
zinc ribbon domain containing 1
chr8_-_49499457 1.24 ENSDART00000098326
opn7d
opsin 7, group member d
chr20_+_733510 1.21 ENSDART00000135066
ENSDART00000015558
ENSDART00000152782
myo6a
myosin VIa
chr22_+_4442473 1.20 ENSDART00000170751
ticam1
toll-like receptor adaptor molecule 1
chr10_+_39200213 1.18 ENSDART00000153727
ei24
etoposide induced 2.4
chr25_+_34862225 1.17 ENSDART00000149782
CHST6
zgc:194879
chr19_+_40069524 1.17 ENSDART00000151365
ENSDART00000140926
zmym4
zinc finger, MYM-type 4
chr15_-_30853246 1.16 ENSDART00000112511
akap1b
A kinase (PRKA) anchor protein 1b
chr2_+_49457449 1.15 ENSDART00000185470
sh3gl1a
SH3-domain GRB2-like 1a
chr8_+_42941555 1.14 ENSDART00000183206
slc23a2
solute carrier family 23 (ascorbic acid transporter), member 2
chr23_-_10175898 1.14 ENSDART00000146185
krt5
keratin 5
chr14_-_33978117 1.12 ENSDART00000128515
foxa
forkhead box A sequence
chr2_+_27386617 1.12 ENSDART00000134976
si:ch73-382f3.1
si:ch73-382f3.1
chr7_-_32895668 1.08 ENSDART00000141828
ano5b
anoctamin 5b
chr7_-_33868903 1.07 ENSDART00000173500
ENSDART00000178746
uacab
uveal autoantigen with coiled-coil domains and ankyrin repeats b
chr7_-_53117131 1.06 ENSDART00000169211
ENSDART00000168890
ENSDART00000172179
ENSDART00000167882
cdh1
cadherin 1, type 1, E-cadherin (epithelial)
chr8_+_26879358 1.05 ENSDART00000132485
rimkla
ribosomal modification protein rimK-like family member A
chr10_-_28028998 1.03 ENSDART00000023545
ENSDART00000143487
ints2
integrator complex subunit 2
chr11_+_31324335 1.03 ENSDART00000088093
sipa1l2
signal-induced proliferation-associated 1 like 2
chr5_+_51833305 1.01 ENSDART00000165276
ENSDART00000166443
papd4
PAP associated domain containing 4
chr10_+_3428194 1.01 ENSDART00000081599
ptpn11a
protein tyrosine phosphatase, non-receptor type 11, a
chr17_+_24597001 1.00 ENSDART00000191834
rlf
rearranged L-myc fusion
chr3_+_26244353 1.00 ENSDART00000103733
atad5a
ATPase family, AAA domain containing 5a
chr15_+_29727799 0.97 ENSDART00000182006
zgc:153372
zgc:153372
chr5_+_40835601 0.97 ENSDART00000147767
si:dkey-3h3.3
si:dkey-3h3.3
chr10_+_17371356 0.96 ENSDART00000122663
sppl3
signal peptide peptidase 3
chr6_-_41138854 0.95 ENSDART00000128723
ENSDART00000151055
ENSDART00000132484
slc6a22.1
solute carrier family 6 member 22, tandem duplicate 1
chr14_+_51056605 0.93 ENSDART00000159639
CABZ01078593.1

chr19_-_43639331 0.93 ENSDART00000138009
ENSDART00000086138
fam83hb
family with sequence similarity 83, member Hb
chr15_-_9321921 0.91 ENSDART00000159676
ENSDART00000033411
trappc4
trafficking protein particle complex 4
chr16_+_53387085 0.89 ENSDART00000154223
ENSDART00000101404
kif13a
kinesin family member 13A
chr25_+_33063762 0.87 ENSDART00000189974
tln2b
talin 2b
chr16_+_24978203 0.86 ENSDART00000156579
si:dkeyp-84f3.5
si:dkeyp-84f3.5
chr23_-_3759345 0.85 ENSDART00000132205
ENSDART00000137707
ENSDART00000189382
hmga1a
high mobility group AT-hook 1a
chr5_+_51833132 0.84 ENSDART00000167491
papd4
PAP associated domain containing 4
chr10_-_36633882 0.80 ENSDART00000077161
ENSDART00000137688
rsf1b.1
rsf1b.1
remodeling and spacing factor 1b, tandem duplicate 1
remodeling and spacing factor 1b, tandem duplicate 1
chr14_+_26247319 0.79 ENSDART00000192793
CCDC69
coiled-coil domain containing 69
chr17_+_27158706 0.79 ENSDART00000151829
rps6ka1
ribosomal protein S6 kinase a, polypeptide 1
chr20_+_31217495 0.78 ENSDART00000020252
pdia6
protein disulfide isomerase family A, member 6
chr10_+_29849497 0.77 ENSDART00000099994
ENSDART00000132212
hspa8
heat shock protein 8
chr22_-_10440688 0.76 ENSDART00000111962
nol8
nucleolar protein 8
chr17_+_5623514 0.75 ENSDART00000171220
ENSDART00000176083
CU571310.1

chr5_+_55221593 0.75 ENSDART00000073638
tmc2a
transmembrane channel-like 2a
chr6_-_11362871 0.74 ENSDART00000151125
pcnt
pericentrin
chr25_-_22889519 0.73 ENSDART00000128250
mob2a
MOB kinase activator 2a
chr10_+_5744941 0.72 ENSDART00000159769
ENSDART00000184734
pam
peptidylglycine alpha-amidating monooxygenase
chr21_+_36396864 0.68 ENSDART00000137309
gemin5
gem (nuclear organelle) associated protein 5
chr19_+_7424347 0.68 ENSDART00000004622
sf3b4
splicing factor 3b, subunit 4
chr22_+_4443689 0.65 ENSDART00000185490
ticam1
toll-like receptor adaptor molecule 1
chr25_+_28567381 0.64 ENSDART00000126552
SLC15A5
si:ch211-190o6.3
chr19_+_16068445 0.62 ENSDART00000138709
gmeb1
glucocorticoid modulatory element binding protein 1
chr7_+_24520518 0.62 ENSDART00000173604
btr09
bloodthirsty-related gene family, member 9
chr13_+_15933168 0.62 ENSDART00000131390
fignl1
fidgetin-like 1
chr6_-_19351495 0.61 ENSDART00000164287
grb2a
growth factor receptor-bound protein 2a
chr13_-_13294847 0.61 ENSDART00000125883
ENSDART00000013534
fgfr3
fibroblast growth factor receptor 3
chr3_+_15773991 0.60 ENSDART00000089923
znf652
zinc finger protein 652
chr5_+_18012154 0.60 ENSDART00000139431
ENSDART00000048859
ascc2
activating signal cointegrator 1 complex subunit 2
chr12_+_19866865 0.59 ENSDART00000045609
cpped1
calcineurin-like phosphoesterase domain containing 1
chr8_+_16990120 0.59 ENSDART00000018934
pde4d
phosphodiesterase 4D, cAMP-specific
chr19_+_24575077 0.58 ENSDART00000167469
si:dkeyp-92c9.4
si:dkeyp-92c9.4
chr23_-_5685023 0.55 ENSDART00000148680
ENSDART00000149365
tnnt2a
troponin T type 2a (cardiac)
chr6_+_58280936 0.55 ENSDART00000155244
ralgapb
Ral GTPase activating protein, beta subunit (non-catalytic)
chr22_+_29113796 0.53 ENSDART00000150264
pla2g6
phospholipase A2, group VI (cytosolic, calcium-independent)
chr13_+_51579851 0.52 ENSDART00000163847
nkx6.2
NK6 homeobox 2
chr9_-_32142311 0.50 ENSDART00000142768
ankrd44
ankyrin repeat domain 44
chr8_+_8671229 0.50 ENSDART00000131963
usp11
ubiquitin specific peptidase 11
chr7_-_49646251 0.48 ENSDART00000193674
hrasb
-Ha-ras Harvey rat sarcoma viral oncogene homolog b
chr9_-_18743012 0.47 ENSDART00000131626
tsc22d1
TSC22 domain family, member 1
chr2_-_30784198 0.46 ENSDART00000182523
ENSDART00000147355
rgs20
regulator of G protein signaling 20
chr9_+_8942258 0.43 ENSDART00000138836
ankrd10b
ankyrin repeat domain 10b
chr15_-_20779624 0.42 ENSDART00000181936
tpst1
tyrosylprotein sulfotransferase 1
chr6_+_54888493 0.42 ENSDART00000113331
nav1b
neuron navigator 1b
chr11_+_34523132 0.40 ENSDART00000192257
zmat3
zinc finger, matrin-type 3
chr25_+_13620555 0.39 ENSDART00000163642
si:ch211-172l8.4
si:ch211-172l8.4
chr11_+_14280598 0.39 ENSDART00000163033
si:ch211-262i1.3
si:ch211-262i1.3
chr22_-_18546241 0.38 ENSDART00000105404
ENSDART00000105405
cirbpb
cold inducible RNA binding protein b
chr5_+_35458346 0.37 ENSDART00000141239
erlin2
ER lipid raft associated 2
chr9_-_18742704 0.37 ENSDART00000145401
tsc22d1
TSC22 domain family, member 1
chr6_-_25180438 0.36 ENSDART00000159696
lrrc8db
leucine rich repeat containing 8 VRAC subunit Db
chr6_-_52675630 0.36 ENSDART00000083830
sdc4
syndecan 4
chr7_+_24006875 0.35 ENSDART00000033755
homezb
homeobox and leucine zipper encoding b
chr12_-_7280551 0.34 ENSDART00000061633
zgc:171971
zgc:171971
chr2_+_26479676 0.33 ENSDART00000056795
ENSDART00000144837
hectd3
HECT domain containing 3
chr5_+_31480342 0.33 ENSDART00000098197
si:dkey-220k22.1
si:dkey-220k22.1
chr1_-_20068155 0.32 ENSDART00000102993
mettl14
methyltransferase like 14
chr7_-_73852594 0.32 ENSDART00000183194
zgc:165555
zgc:165555
chr17_+_7534180 0.31 ENSDART00000187512
shprh
SNF2 histone linker PHD RING helicase
chr7_+_25103965 0.29 ENSDART00000192561
ENSDART00000173721
si:dkey-23i12.9
si:dkey-23i12.9
chr1_-_31534089 0.29 ENSDART00000007770
lbx1b
ladybird homeobox 1b
chr9_-_22272181 0.29 ENSDART00000113174
crygm2d7
crystallin, gamma M2d7
chr9_-_22318511 0.28 ENSDART00000129295
crygm2d2
crystallin, gamma M2d2
chr1_-_18615063 0.28 ENSDART00000014916
klf3
Kruppel-like factor 3 (basic)
chr22_+_17531214 0.28 ENSDART00000161174
ENSDART00000088356
hnrnpm
heterogeneous nuclear ribonucleoprotein M
chr22_-_10570749 0.26 ENSDART00000140736
si:dkey-42i9.6
si:dkey-42i9.6
chr17_+_7534365 0.25 ENSDART00000157123
shprh
SNF2 histone linker PHD RING helicase
chr17_-_45386546 0.24 ENSDART00000182647
tmem206
transmembrane protein 206
chr1_+_41690402 0.23 ENSDART00000177298
fbxo41
F-box protein 41
chr6_-_7735153 0.23 ENSDART00000151545
slc25a38b
solute carrier family 25, member 38b
chr9_-_9242777 0.23 ENSDART00000021191
u2af1
U2 small nuclear RNA auxiliary factor 1
chr8_+_17869225 0.23 ENSDART00000080079
slc44a5b
solute carrier family 44, member 5b
chr12_+_40810418 0.23 ENSDART00000183393
CDH18
cadherin 18
chr5_+_42912966 0.22 ENSDART00000039973
rufy3
RUN and FYVE domain containing 3
chr12_+_22657925 0.20 ENSDART00000153048
si:dkey-219e21.4
si:dkey-219e21.4
chr23_+_3538463 0.19 ENSDART00000172758
si:dkey-9l20.3
si:dkey-9l20.3
chr12_+_19320657 0.17 ENSDART00000100075
ENSDART00000066389
tmem184ba
transmembrane protein 184ba
chr23_-_33944597 0.17 ENSDART00000133223
si:dkey-190g6.2
si:dkey-190g6.2
chr1_+_26480890 0.17 ENSDART00000164430
uso1
USO1 vesicle transport factor
chr25_+_13271458 0.16 ENSDART00000188307
AL772241.1

chr21_+_349091 0.16 ENSDART00000183693
ZNF462
zinc finger protein 462
chr4_+_65607540 0.16 ENSDART00000192218
si:dkey-205i10.2
si:dkey-205i10.2
chr22_-_15693085 0.15 ENSDART00000141861
si:ch1073-396h14.1
si:ch1073-396h14.1
chr12_+_33151246 0.15 ENSDART00000162681
rbfox3a
RNA binding fox-1 homolog 3a
chr2_+_29257942 0.13 ENSDART00000184362
ENSDART00000025562
cdh18a
cadherin 18, type 2a
chr15_-_5563551 0.12 ENSDART00000099520
atg16l2
ATG16 autophagy related 16-like 2 (S. cerevisiae)
chr17_-_44776224 0.12 ENSDART00000156195
zdhhc22
zinc finger, DHHC-type containing 22
chr21_-_9914745 0.12 ENSDART00000172124
arhgap24
Rho GTPase activating protein 24
chr21_-_41028665 0.11 ENSDART00000190531
plac8l1
PLAC8-like 1
chr21_-_43550120 0.11 ENSDART00000151627
si:ch73-362m14.2
si:ch73-362m14.2
chr4_-_5291256 0.10 ENSDART00000150864
SNAP91 (1 of many)
si:ch211-214j24.9
chr9_+_50001746 0.10 ENSDART00000058892
slc38a11
solute carrier family 38, member 11
chr24_-_29868151 0.09 ENSDART00000184802
aglb
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase b
chr11_+_10541258 0.08 ENSDART00000132365
b3gnt5a
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5a
chr10_-_25628555 0.08 ENSDART00000143978
tiam1a
T cell lymphoma invasion and metastasis 1a
chr3_-_9444749 0.08 ENSDART00000182191
FO904885.3

chr17_-_45386823 0.07 ENSDART00000156002
tmem206
transmembrane protein 206
chr20_-_40754794 0.07 ENSDART00000187251
cx32.3
connexin 32.3
chr7_+_31145386 0.07 ENSDART00000075407
ENSDART00000169462
fam189a1
family with sequence similarity 189, member A1
chr18_+_47313899 0.07 ENSDART00000192389
ENSDART00000189592
ENSDART00000184281
barx2
BARX homeobox 2
chr8_+_26205471 0.07 ENSDART00000131888
celsr3
cadherin, EGF LAG seven-pass G-type receptor 3
chr3_+_3992590 0.07 ENSDART00000180211
ENSDART00000054840
BX005421.2

chr10_-_42237304 0.06 ENSDART00000140341
tcf7l1a
transcription factor 7 like 1a
chr5_+_19097194 0.06 ENSDART00000131918
unc13ba
unc-13 homolog Ba (C. elegans)
chr9_-_22339582 0.06 ENSDART00000134805
crygm2d1
crystallin, gamma M2d1
chr15_-_5239536 0.06 ENSDART00000081704
or128-2
odorant receptor, family E, subfamily 128, member 2
chr11_-_7147540 0.06 ENSDART00000143942
bmp7a
bone morphogenetic protein 7a
chr15_+_31462664 0.05 ENSDART00000174267
ENSDART00000185665
ENSDART00000060087
or102-1
odorant receptor, family C, subfamily 102, member 1
chr2_+_23731194 0.05 ENSDART00000155747
slc22a13a
solute carrier family 22 member 13a
chr5_+_25317061 0.05 ENSDART00000170097
trpm6
transient receptor potential cation channel, subfamily M, member 6
chr12_-_30523216 0.05 ENSDART00000152896
ENSDART00000153191
plekhs1
pleckstrin homology domain containing, family S member 1
chr4_+_57046954 0.04 ENSDART00000171796
si:ch211-238e22.7
si:ch211-238e22.7
chr13_-_11699530 0.04 ENSDART00000192161
slc39a8
solute carrier family 39 (zinc transporter), member 8
chr20_+_40237441 0.04 ENSDART00000168928
si:ch211-199i15.5
si:ch211-199i15.5
chr9_+_3055566 0.04 ENSDART00000189906
ENSDART00000175891
ENSDART00000093021
ppp1r9ala
protein phosphatase 1 regulatory subunit 9A-like A
chr7_-_13362590 0.04 ENSDART00000091616
sdhaf2
succinate dehydrogenase complex assembly factor 2
chr19_+_4051695 0.03 ENSDART00000166368
btr24
bloodthirsty-related gene family, member 24
chr24_-_31194847 0.03 ENSDART00000158808
cnn3a
calponin 3, acidic a
chr5_-_46505691 0.03 ENSDART00000111589
ENSDART00000122966
ENSDART00000166907
hapln1a
hyaluronan and proteoglycan link protein 1a
chr4_-_27301356 0.03 ENSDART00000100444
fam19a5a
family with sequence similarity 19 (chemokine (C-C motif)-like), member A5a
chr5_-_33606729 0.02 ENSDART00000137073
si:dkey-34e4.1
si:dkey-34e4.1
chr25_+_26798673 0.01 ENSDART00000157235
ca12
carbonic anhydrase XII
chr16_-_42186093 0.01 ENSDART00000076030
fbl
fibrillarin
chr22_+_30631072 0.01 ENSDART00000059970
zmp:0000000606
zmp:0000000606
chr15_-_41503392 0.01 ENSDART00000169351
si:dkey-230i18.2
si:dkey-230i18.2
chr7_-_24373662 0.01 ENSDART00000173865
PTGR1 (1 of many)
si:dkey-11k2.7
chr6_+_52889353 0.01 ENSDART00000174115
or137-9
odorant receptor, family H, subfamily 137, member 9
chr4_+_29702703 0.01 ENSDART00000167771
si:ch211-214c20.1
si:ch211-214c20.1
chr9_-_14084044 0.01 ENSDART00000141571
fer1l6
fer-1-like family member 6
chr15_+_5287703 0.00 ENSDART00000157261
or122-1
odorant receptor, family E, subfamily 122, member 1

Network of associatons between targets according to the STRING database.

First level regulatory network of sox6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.9 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.7 2.9 GO:0070987 error-free translesion synthesis(GO:0070987)
0.6 1.9 GO:0042730 fibrinolysis(GO:0042730)
0.6 1.9 GO:0032814 regulation of natural killer cell activation(GO:0032814) positive regulation of natural killer cell activation(GO:0032816) TRIF-dependent toll-like receptor signaling pathway(GO:0035666)
0.6 9.9 GO:0035803 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.5 2.5 GO:0010482 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.5 2.0 GO:0051352 negative regulation of ligase activity(GO:0051352) negative regulation of ubiquitin-protein transferase activity(GO:0051444) negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.4 1.3 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
0.4 1.1 GO:0019852 L-ascorbic acid transport(GO:0015882) L-ascorbic acid metabolic process(GO:0019852)
0.4 1.1 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.3 1.0 GO:0018872 arsonoacetate metabolic process(GO:0018872)
0.3 0.9 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.2 1.1 GO:0090134 adherens junction maintenance(GO:0034334) mesendoderm migration(GO:0090133) cell migration involved in mesendoderm migration(GO:0090134)
0.2 1.9 GO:0050435 beta-amyloid metabolic process(GO:0050435)
0.2 1.2 GO:0035479 angioblast cell migration from lateral mesoderm to midline(GO:0035479)
0.1 0.6 GO:0003228 atrial cardiac muscle tissue development(GO:0003228)
0.1 1.9 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.1 0.8 GO:1902946 positive regulation of receptor-mediated endocytosis(GO:0048260) protein localization to early endosome(GO:1902946)
0.1 4.9 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.1 0.7 GO:0030033 microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
0.1 1.6 GO:0046599 regulation of centriole replication(GO:0046599)
0.1 1.0 GO:0006465 signal peptide processing(GO:0006465)
0.1 1.1 GO:0032196 transposition(GO:0032196)
0.1 0.3 GO:0002155 regulation of thyroid hormone mediated signaling pathway(GO:0002155)
0.1 2.2 GO:0070897 DNA-templated transcriptional preinitiation complex assembly(GO:0070897)
0.1 1.6 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.1 0.9 GO:0072386 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.1 0.4 GO:0048103 neuronal stem cell division(GO:0036445) somatic stem cell division(GO:0048103)
0.1 0.7 GO:0060004 reflex(GO:0060004) vestibular reflex(GO:0060005)
0.1 0.2 GO:1904983 transmembrane glycine transport from cytosol to mitochondrion(GO:1904983)
0.1 1.2 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.1 0.3 GO:0010610 regulation of mRNA stability involved in response to stress(GO:0010610) regulation of mRNA stability involved in response to oxidative stress(GO:2000815)
0.1 1.5 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.1 0.3 GO:0060019 radial glial cell differentiation(GO:0060019)
0.1 1.1 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1 2.8 GO:0030901 midbrain development(GO:0030901)
0.1 0.4 GO:0006477 protein sulfation(GO:0006477) peptidyl-tyrosine sulfation(GO:0006478)
0.0 5.9 GO:0008285 negative regulation of cell proliferation(GO:0008285)
0.0 0.2 GO:0048211 Golgi vesicle docking(GO:0048211)
0.0 3.8 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 1.0 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.6 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.4 GO:0032933 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 1.2 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.1 GO:0039703 viral genome replication(GO:0019079) negative stranded viral RNA replication(GO:0039689) viral RNA genome replication(GO:0039694) RNA replication(GO:0039703) multi-organism biosynthetic process(GO:0044034)
0.0 2.2 GO:0031101 fin regeneration(GO:0031101)
0.0 0.9 GO:0045103 intermediate filament-based process(GO:0045103) intermediate filament cytoskeleton organization(GO:0045104)
0.0 2.2 GO:0008360 regulation of cell shape(GO:0008360)
0.0 0.1 GO:1900028 wound healing, spreading of epidermal cells(GO:0035313) wound healing, spreading of cells(GO:0044319) epiboly involved in wound healing(GO:0090505) negative regulation of ruffle assembly(GO:1900028)
0.0 0.3 GO:0003310 pancreatic A cell differentiation(GO:0003310)
0.0 1.4 GO:0033339 pectoral fin development(GO:0033339)
0.0 0.3 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 0.0 GO:0071421 manganese ion transmembrane transport(GO:0071421)
0.0 0.1 GO:0021703 locus ceruleus development(GO:0021703)
0.0 1.7 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.7 GO:0030217 T cell differentiation(GO:0030217)
0.0 1.1 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.1 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.3 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 1.7 GO:0051604 protein maturation(GO:0051604)
0.0 0.1 GO:0016081 synaptic vesicle docking(GO:0016081) presynaptic dense core granule exocytosis(GO:0099525)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.5 GO:0044326 dendritic spine neck(GO:0044326) dendritic filopodium(GO:1902737)
0.3 1.9 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.3 2.2 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.3 0.8 GO:0031213 RSF complex(GO:0031213)
0.2 1.0 GO:0071556 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.2 2.1 GO:0045095 keratin filament(GO:0045095)
0.1 0.3 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.1 0.4 GO:0043194 axon initial segment(GO:0043194)
0.1 1.1 GO:0030057 desmosome(GO:0030057)
0.1 0.9 GO:0030008 TRAPP complex(GO:0030008)
0.0 1.0 GO:0032039 integrator complex(GO:0032039)
0.0 0.9 GO:0016282 eukaryotic 43S preinitiation complex(GO:0016282)
0.0 2.4 GO:0031901 early endosome membrane(GO:0031901)
0.0 3.9 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.7 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 1.2 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.2 GO:0089701 U2AF(GO:0089701)
0.0 0.9 GO:0001726 ruffle(GO:0001726)
0.0 8.9 GO:0031012 extracellular matrix(GO:0031012)
0.0 1.6 GO:0005814 centriole(GO:0005814)
0.0 0.3 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.0 0.3 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 1.7 GO:0016607 nuclear speck(GO:0016607)
0.0 0.8 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 1.1 GO:0000123 histone acetyltransferase complex(GO:0000123)
0.0 0.5 GO:0005861 troponin complex(GO:0005861)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 4.9 GO:0071889 14-3-3 protein binding(GO:0071889)
0.9 9.9 GO:0035804 structural constituent of egg coat(GO:0035804)
0.3 1.0 GO:0072591 N-acetyl-L-aspartate-L-glutamate ligase activity(GO:0072590) citrate-L-glutamate ligase activity(GO:0072591)
0.3 1.0 GO:0030791 arsenite methyltransferase activity(GO:0030791) methylarsonite methyltransferase activity(GO:0030792)
0.3 3.8 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.3 2.2 GO:0000995 transcription factor activity, core RNA polymerase III binding(GO:0000995)
0.3 0.9 GO:0098808 mRNA cap binding(GO:0098808)
0.2 0.7 GO:0016842 amidine-lyase activity(GO:0016842)
0.2 1.9 GO:0005158 insulin receptor binding(GO:0005158)
0.1 2.9 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 1.0 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 0.3 GO:0001734 mRNA (N6-adenosine)-methyltransferase activity(GO:0001734)
0.1 1.3 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 1.8 GO:0008301 DNA binding, bending(GO:0008301)
0.1 1.1 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 0.9 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.1 0.8 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.1 1.2 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.1 0.8 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.1 0.4 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.1 0.8 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.6 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.5 GO:0031013 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.0 1.5 GO:0045182 translation regulator activity(GO:0045182)
0.0 1.7 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 2.1 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.1 GO:0008457 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.0 1.4 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 1.2 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.6 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.2 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 1.2 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.7 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.1 GO:0004134 glycogen debranching enzyme activity(GO:0004133) 4-alpha-glucanotransferase activity(GO:0004134) amylo-alpha-1,6-glucosidase activity(GO:0004135)
0.0 0.2 GO:0048039 ubiquinone binding(GO:0048039)
0.0 0.2 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.2 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 3.5 GO:0042802 identical protein binding(GO:0042802)
0.0 0.9 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 1.3 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.0 0.3 GO:0034062 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.5 GO:0019003 GDP binding(GO:0019003)
0.0 0.1 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 1.1 GO:0005254 chloride channel activity(GO:0005254)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 5.7 PID MTOR 4PATHWAY mTOR signaling pathway
0.1 0.9 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.1 1.1 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 1.3 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 2.0 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.4 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 1.1 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.6 PID FGF PATHWAY FGF signaling pathway
0.0 0.5 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 0.2 PID ARF 3PATHWAY Arf1 pathway
0.0 0.8 PID CMYB PATHWAY C-MYB transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.9 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.4 1.1 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.2 3.8 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.2 1.9 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.1 0.6 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.1 2.0 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.1 0.8 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS Genes involved in CREB phosphorylation through the activation of Ras
0.1 0.8 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.5 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 1.2 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 1.4 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.4 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.7 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 2.9 REACTOME DNA REPAIR Genes involved in DNA Repair
0.0 1.1 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.9 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.8 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.7 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.2 REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM Genes involved in Transport of Mature Transcript to Cytoplasm
0.0 0.5 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.2 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions