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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for sox9a+sox9b

Z-value: 1.78

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Transcription factors associated with sox9a+sox9b

Gene Symbol Gene ID Gene Info
sox9a
ENSDARG00000003293 SRY-box transcription factor 9a
sox9b
ENSDARG00000043923 SRY-box transcription factor 9b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
sox9adr11_v1_chr12_-_1951233_1951284-0.945.3e-09Click!
sox9bdr11_v1_chr3_-_62527675_625276960.933.2e-08Click!

Activity profile of sox9a+sox9b motif

Sorted Z-values of sox9a+sox9b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr8_-_32385989 7.15 ENSDART00000143716
ENSDART00000098850
lipg
lipase, endothelial
chr19_+_14109348 5.94 ENSDART00000159015
zgc:175136
zgc:175136
chr5_+_57924611 5.60 ENSDART00000050949
btg4
B-cell translocation gene 4
chr18_+_45571378 5.36 ENSDART00000077251
kifc3
kinesin family member C3
chr24_-_2381143 5.25 ENSDART00000144307
rreb1a
ras responsive element binding protein 1a
chr7_+_58751504 4.89 ENSDART00000024185
zgc:56231
zgc:56231
chr16_+_35535375 4.66 ENSDART00000171675
cited4b
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4b
chr23_+_36308428 4.10 ENSDART00000134607
hnrnpa1b
heterogeneous nuclear ribonucleoprotein A1b
chr20_+_54304800 4.05 ENSDART00000121661
zp2.6
zona pellucida glycoprotein 2, tandem duplicate 6
chr24_-_41797681 4.02 ENSDART00000169643
arhgap28
Rho GTPase activating protein 28
chr16_+_35535171 4.02 ENSDART00000167001
cited4b
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4b
chr10_+_15255012 4.01 ENSDART00000023766
vldlr
very low density lipoprotein receptor
chr10_+_15255198 3.99 ENSDART00000139047
ENSDART00000172107
ENSDART00000183413
ENSDART00000185314
vldlr
very low density lipoprotein receptor
chr22_-_10541372 3.88 ENSDART00000179708
si:dkey-42i9.4
si:dkey-42i9.4
chr20_+_54295213 3.88 ENSDART00000074085
zp2.3
zona pellucida glycoprotein 2, tandem duplicate 3
chr16_+_26846495 3.84 ENSDART00000078124
trim35-29
tripartite motif containing 35-29
chr20_+_54299419 3.82 ENSDART00000056089
ENSDART00000193107
si:zfos-1505d6.3
si:zfos-1505d6.3
chr20_+_54312970 3.81 ENSDART00000024598
ENSDART00000193172
zp2.5
zona pellucida glycoprotein 2, tandem duplicate 5
chr15_+_29025090 3.76 ENSDART00000131755
si:ch211-137a8.2
si:ch211-137a8.2
chr20_+_54309148 3.73 ENSDART00000099360
zp2.1
zona pellucida glycoprotein 2, tandem duplicate 1
chr18_-_7032227 3.61 ENSDART00000127138
calub
calumenin b
chr20_+_54290356 3.61 ENSDART00000173347
zp2.2
zona pellucida glycoprotein 2, tandem duplicate 2
chr17_-_45125537 3.56 ENSDART00000113552
zgc:163014
zgc:163014
chr8_-_410199 3.54 ENSDART00000091177
ENSDART00000122979
ENSDART00000151331
ENSDART00000151155
trim36
tripartite motif containing 36
chr8_-_44611357 3.35 ENSDART00000063396
bag4
BCL2 associated athanogene 4
chr24_-_19719240 3.32 ENSDART00000135405
csrnp1b
cysteine-serine-rich nuclear protein 1b
chr3_+_32411343 3.20 ENSDART00000186287
ENSDART00000141793
rras
RAS related
chr22_-_22337382 3.10 ENSDART00000144684
si:ch211-129c21.1
si:ch211-129c21.1
chr12_+_30788912 3.10 ENSDART00000160422
aldh18a1
aldehyde dehydrogenase 18 family, member A1
chr3_+_32410746 3.06 ENSDART00000025496
rras
RAS related
chr19_+_7549854 3.02 ENSDART00000138866
ENSDART00000151758
pbxip1a
pre-B-cell leukemia homeobox interacting protein 1a
chr22_+_15960514 3.00 ENSDART00000181617
stil
scl/tal1 interrupting locus
chr11_-_44979281 2.90 ENSDART00000190972
ldb1b
LIM-domain binding 1b
chr5_-_56964547 2.82 ENSDART00000074400
tia1
TIA1 cytotoxic granule-associated RNA binding protein
chr13_-_35907768 2.80 ENSDART00000147522
mycla
MYCL proto-oncogene, bHLH transcription factor a
chr22_+_14117078 2.79 ENSDART00000013575
bzw1a
basic leucine zipper and W2 domains 1a
chr13_-_36761379 2.78 ENSDART00000131534
ENSDART00000029824
map4k5
mitogen-activated protein kinase kinase kinase kinase 5
chr9_-_46415847 2.77 ENSDART00000009790
cx43.4
connexin 43.4
chr2_+_32846602 2.75 ENSDART00000056649
tmem53
transmembrane protein 53
chr24_-_1985007 2.72 ENSDART00000189870
PARD3 (1 of many)
par-3 family cell polarity regulator
chr13_-_35908275 2.71 ENSDART00000013961
mycla
MYCL proto-oncogene, bHLH transcription factor a
chr14_-_41478265 2.71 ENSDART00000149886
ENSDART00000016002
tspan7
tetraspanin 7
chr6_-_46742455 2.70 ENSDART00000011970
zgc:66479
zgc:66479
chr5_+_44846434 2.69 ENSDART00000145299
ENSDART00000136521
kank1a
KN motif and ankyrin repeat domains 1a
chr4_-_837768 2.68 ENSDART00000185280
ENSDART00000135618
sobpb
sine oculis binding protein homolog (Drosophila) b
chr7_+_22801465 2.67 ENSDART00000052862
ENSDART00000173633
rbm4.1
RNA binding motif protein 4.1
chr11_+_41838801 2.66 ENSDART00000014871
akr7a3
aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase)
chr21_-_30082414 2.64 ENSDART00000157307
ENSDART00000155188
ccnjl
cyclin J-like
chr2_+_34967022 2.56 ENSDART00000134926
astn1
astrotactin 1
chr13_-_6250317 2.56 ENSDART00000180416
tuba4l
tubulin, alpha 4 like
chr15_-_16076399 2.54 ENSDART00000135658
ENSDART00000133755
ENSDART00000080413
srsf1a
serine/arginine-rich splicing factor 1a
chr2_+_44512324 2.53 ENSDART00000155017
ENSDART00000156310
ENSDART00000156686
pask
PAS domain containing serine/threonine kinase
chr14_+_16287968 2.52 ENSDART00000106593
prpf19
pre-mRNA processing factor 19
chr22_-_5171362 2.52 ENSDART00000124889
tnfaip8l1
tumor necrosis factor, alpha-induced protein 8-like 1
chr3_+_54047342 2.52 ENSDART00000178486
olfm2a
olfactomedin 2a
chr10_-_36691681 2.50 ENSDART00000122375
mrpl48
mitochondrial ribosomal protein L48
chr22_+_15960005 2.50 ENSDART00000033617
stil
scl/tal1 interrupting locus
chr5_+_44846280 2.48 ENSDART00000084370
kank1a
KN motif and ankyrin repeat domains 1a
chr16_-_54919260 2.45 ENSDART00000156533
kdf1a
keratinocyte differentiation factor 1a
chr22_+_15959844 2.42 ENSDART00000182201
stil
scl/tal1 interrupting locus
chr9_-_14273652 2.40 ENSDART00000135458
abcb6b
ATP-binding cassette, sub-family B (MDR/TAP), member 6b
chr5_+_58679071 2.39 ENSDART00000019561
zgc:171734
zgc:171734
chr23_+_35426404 2.39 ENSDART00000164658
si:ch211-225h24.2
si:ch211-225h24.2
chr23_+_19590006 2.39 ENSDART00000021231
slmapb
sarcolemma associated protein b
chr2_+_34967210 2.38 ENSDART00000141796
astn1
astrotactin 1
chr6_+_33931095 2.37 ENSDART00000191909
orc1
origin recognition complex, subunit 1
chr15_-_31265375 2.37 ENSDART00000086592
vezf1b
vascular endothelial zinc finger 1b
chr5_-_22130937 2.36 ENSDART00000138606
las1l
LAS1-like, ribosome biogenesis factor
chr14_-_16810401 2.36 ENSDART00000158396
ENSDART00000170758
tcirg1b
T cell immune regulator 1, ATPase H+ transporting V0 subunit a3b
chr9_-_28937880 2.34 ENSDART00000132878
epb41l5
erythrocyte membrane protein band 4.1 like 5
chr1_+_49878000 2.34 ENSDART00000047876
lef1
lymphoid enhancer-binding factor 1
chr14_-_32876280 2.30 ENSDART00000173168
si:rp71-46j2.7
si:rp71-46j2.7
chr14_-_26704829 2.29 ENSDART00000078563
neurog1
neurogenin 1
chr17_+_14965570 2.26 ENSDART00000066604
gpr137c
G protein-coupled receptor 137c
chr19_+_46113828 2.25 ENSDART00000159331
ENSDART00000161826
rbm24a
RNA binding motif protein 24a
chr21_-_11054605 2.25 ENSDART00000191378
ENSDART00000084061
nedd4l
neural precursor cell expressed, developmentally down-regulated 4-like
chr1_+_16574312 2.22 ENSDART00000187067
mtus1b
microtubule associated tumor suppressor 1b
chr18_-_38270430 2.22 ENSDART00000139519
caprin1b
cell cycle associated protein 1b
chr3_+_53156813 2.20 ENSDART00000114343
brd4
bromodomain containing 4
chr12_+_48340133 2.20 ENSDART00000152899
ENSDART00000153335
ENSDART00000054788
ddit4
DNA-damage-inducible transcript 4
chr9_+_24192370 2.18 ENSDART00000003482
stk17b
serine/threonine kinase 17b (apoptosis-inducing)
chr17_+_28005763 2.18 ENSDART00000155838
luzp1
leucine zipper protein 1
chr23_-_40536017 2.12 ENSDART00000153751
ENSDART00000140623
ENSDART00000133356
rnf146
ring finger protein 146
chr7_+_19850889 2.12 ENSDART00000100782
mus81
MUS81 structure-specific endonuclease subunit
chr23_-_14403939 2.08 ENSDART00000090930
nkain4
sodium/potassium transporting ATPase interacting 4
chr14_+_38786298 2.05 ENSDART00000164440
si:ch211-195b11.3
si:ch211-195b11.3
chr6_-_49547680 2.04 ENSDART00000169678
ppp4r1l
protein phosphatase 4, regulatory subunit 1-like
chr14_+_34490445 2.03 ENSDART00000132193
ENSDART00000148044
wnt8a
wingless-type MMTV integration site family, member 8a
chr19_+_41479990 2.03 ENSDART00000087187
ago2
argonaute RISC catalytic component 2
chr13_+_33368503 2.01 ENSDART00000139650
brf1a
BRF1, RNA polymerase III transcription initiation factor a
chr22_-_6420239 2.00 ENSDART00000148385
zgc:171699
zgc:171699
chr9_-_34260214 1.99 ENSDART00000012385
me3
malic enzyme 3, NADP(+)-dependent, mitochondrial
chr6_-_11362871 1.99 ENSDART00000151125
pcnt
pericentrin
chr20_-_3319642 1.97 ENSDART00000186743
ENSDART00000123096
marcksa
myristoylated alanine-rich protein kinase C substrate a
chr10_-_28028998 1.97 ENSDART00000023545
ENSDART00000143487
ints2
integrator complex subunit 2
chr3_+_36127287 1.96 ENSDART00000058605
ENSDART00000182500
scpep1
serine carboxypeptidase 1
chr16_+_35905031 1.95 ENSDART00000162411
sh3d21
SH3 domain containing 21
chr1_+_46493944 1.94 ENSDART00000114083
mcf2la
mcf.2 cell line derived transforming sequence-like a
chr3_-_26805455 1.93 ENSDART00000180648
pigq
phosphatidylinositol glycan anchor biosynthesis, class Q
chr2_-_27651674 1.92 ENSDART00000177402
tgs1
trimethylguanosine synthase 1
chr7_-_39378903 1.92 ENSDART00000173659
slc8b1
solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
chr11_-_27057572 1.91 ENSDART00000043091
iqsec1b
IQ motif and Sec7 domain 1b
chr10_+_15608326 1.90 ENSDART00000188770
zfand5b
zinc finger, AN1-type domain 5b
chr15_+_11644866 1.90 ENSDART00000188716
slc1a5
solute carrier family 1 (neutral amino acid transporter), member 5
chr21_+_37513058 1.89 ENSDART00000141096
amot
angiomotin
chr7_-_39360325 1.88 ENSDART00000098033
ENSDART00000173695
ENSDART00000173466
ENSDART00000173734
ambra1a
autophagy/beclin-1 regulator 1a
chr14_+_16036139 1.88 ENSDART00000190733
prelid1a
PRELI domain containing 1a
chr20_+_13141408 1.88 ENSDART00000034098
dtl
denticleless E3 ubiquitin protein ligase homolog (Drosophila)
chr2_+_36608387 1.85 ENSDART00000159541
pak2a
p21 protein (Cdc42/Rac)-activated kinase 2a
chr17_+_38602790 1.84 ENSDART00000062010
ccdc88c
coiled-coil domain containing 88C
chr20_+_26943072 1.84 ENSDART00000153215
cdca4
cell division cycle associated 4
chr1_+_218524 1.82 ENSDART00000109529
tmco3
transmembrane and coiled-coil domains 3
chr6_-_12172424 1.82 ENSDART00000109344
tanc1a
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1a
chr9_-_22057658 1.81 ENSDART00000101944
crygmxl1
crystallin, gamma MX, like 1
chr5_-_41124241 1.81 ENSDART00000083561
mtmr12
myotubularin related protein 12
chr1_+_52632856 1.76 ENSDART00000011725
slc44a1a
solute carrier family 44 (choline transporter), member 1a
chr21_+_37513488 1.76 ENSDART00000185394
amot
angiomotin
chr12_-_3053699 1.75 ENSDART00000139721
dcxr
dicarbonyl/L-xylulose reductase
chr20_-_31238313 1.74 ENSDART00000028471
hpcal1
hippocalcin-like 1
chr5_+_56277866 1.74 ENSDART00000170610
ENSDART00000028854
ENSDART00000148749
aatf
apoptosis antagonizing transcription factor
chr1_-_21714025 1.74 ENSDART00000129066
zcchc7
zinc finger, CCHC domain containing 7
chr21_-_11054876 1.72 ENSDART00000146576
nedd4l
neural precursor cell expressed, developmentally down-regulated 4-like
chr12_+_33460794 1.70 ENSDART00000007053
ENSDART00000142716
narf
nuclear prelamin A recognition factor
chr24_-_2423791 1.69 ENSDART00000190402
rreb1a
ras responsive element binding protein 1a
chr10_-_15879569 1.69 ENSDART00000136789
tjp2a
tight junction protein 2a (zona occludens 2)
chr23_-_29357764 1.68 ENSDART00000156512
si:ch211-129o18.4
si:ch211-129o18.4
chr24_-_22103585 1.68 ENSDART00000000070
dap
death-associated protein
chr25_+_35891342 1.68 ENSDART00000147093
lsm14aa
LSM14A mRNA processing body assembly factor a
chr20_-_40766387 1.66 ENSDART00000061173
hsdl1
hydroxysteroid dehydrogenase like 1
chr15_+_25439106 1.66 ENSDART00000156252
aifm4
apoptosis-inducing factor, mitochondrion-associated, 4
chr25_+_18475032 1.65 ENSDART00000073564
tes
testis derived transcript (3 LIM domains)
chr3_+_17653784 1.64 ENSDART00000159984
ENSDART00000157682
ENSDART00000187937
kat2a
K(lysine) acetyltransferase 2A
chr23_+_9522942 1.63 ENSDART00000137751
osbpl2b
oxysterol binding protein-like 2b
chr2_-_21167652 1.63 ENSDART00000185792
bmi1b
bmi1 polycomb ring finger oncogene 1b
chr20_+_6533260 1.62 ENSDART00000135005
ENSDART00000166356
si:ch211-191a24.4
si:ch211-191a24.4
chr8_+_42941555 1.61 ENSDART00000183206
slc23a2
solute carrier family 23 (ascorbic acid transporter), member 2
chr12_+_16953415 1.59 ENSDART00000020824
pank1b
pantothenate kinase 1b
chr11_+_18873619 1.59 ENSDART00000176141
magi1b
membrane associated guanylate kinase, WW and PDZ domain containing 1b
chr14_-_24277805 1.58 ENSDART00000054243
dpf2l
D4, zinc and double PHD fingers family 2, like
chr23_+_38171186 1.57 ENSDART00000148188
zgc:112994
zgc:112994
chr21_+_17301790 1.57 ENSDART00000145057
tsc1b
TSC complex subunit 1b
chr6_+_32326074 1.57 ENSDART00000042134
ENSDART00000181177
dock7
dedicator of cytokinesis 7
chr4_-_12040322 1.55 ENSDART00000150583
ENSDART00000102260
si:dkey-222f8.3
si:dkey-222f8.3
chr17_+_33415319 1.54 ENSDART00000140805
ENSDART00000025501
ENSDART00000146447
snap23.1
synaptosomal-associated protein 23.1
chr10_-_28027490 1.53 ENSDART00000185445
ints2
integrator complex subunit 2
chr4_+_5334202 1.53 ENSDART00000150409
apex1
APEX nuclease (multifunctional DNA repair enzyme) 1
chr7_+_32897723 1.51 ENSDART00000146789
ENSDART00000140775
ENSDART00000142049
ENSDART00000145523
ENSDART00000135237
ENSDART00000133584
ENSDART00000140800
ENSDART00000137956
ENSDART00000075263
tssc4
tumor suppressing subtransferable candidate 4
chr9_-_41401564 1.50 ENSDART00000059628
nab1b
NGFI-A binding protein 1b (EGR1 binding protein 1)
chr21_+_38089036 1.50 ENSDART00000147219
klf8
Kruppel-like factor 8
chr15_+_23947932 1.50 ENSDART00000153951
myo18ab
myosin XVIIIAb
chr2_-_5135125 1.49 ENSDART00000164039
ptmab
prothymosin, alpha b
chr20_+_1272526 1.49 ENSDART00000008115
ENSDART00000133825
hsd3b2
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
chr23_+_9522781 1.47 ENSDART00000136486
osbpl2b
oxysterol binding protein-like 2b
chr23_-_27050083 1.47 ENSDART00000142324
ENSDART00000133249
ENSDART00000138751
ENSDART00000128718
zgc:66440
zgc:66440
chr21_+_19368720 1.47 ENSDART00000187759
ENSDART00000185829
ENSDART00000158471
ENSDART00000168728
btc
betacellulin, epidermal growth factor family member
chr19_-_34011340 1.47 ENSDART00000172618
elmo1
engulfment and cell motility 1 (ced-12 homolog, C. elegans)
chr3_-_45778123 1.46 ENSDART00000146211
h3f3b.1
H3 histone, family 3B.1
chr18_+_17493859 1.46 ENSDART00000090754
si:dkey-102f14.5
si:dkey-102f14.5
chr6_-_15491579 1.46 ENSDART00000156439
st6gal2b
ST6 beta-galactosamide alpha-2,6-sialyltranferase 2b
chr19_-_31042570 1.46 ENSDART00000144337
ENSDART00000136213
ENSDART00000133101
ENSDART00000190949
bzw2
basic leucine zipper and W2 domains 2
chr14_-_33978117 1.45 ENSDART00000128515
foxa
forkhead box A sequence
chr2_+_2967255 1.44 ENSDART00000167649
ENSDART00000166449
pik3r3a
phosphoinositide-3-kinase, regulatory subunit 3a (gamma)
chr15_-_20839763 1.44 ENSDART00000141746
ENSDART00000182369
aldh3a2a
aldehyde dehydrogenase 3 family, member A2a
chr18_+_36066389 1.43 ENSDART00000059347
bckdha
branched chain keto acid dehydrogenase E1, alpha polypeptide
chr22_+_4443689 1.43 ENSDART00000185490
ticam1
toll-like receptor adaptor molecule 1
chr6_-_37743724 1.42 ENSDART00000149068
nipa2
non imprinted in Prader-Willi/Angelman syndrome 2 (human)
chr14_+_31473866 1.42 ENSDART00000173088
ccdc160
coiled-coil domain containing 160
chr18_-_38270077 1.41 ENSDART00000185546
caprin1b
cell cycle associated protein 1b
chr23_+_37482727 1.40 ENSDART00000162737
agmat
agmatine ureohydrolase (agmatinase)
chr9_-_34500197 1.40 ENSDART00000114043
ppp2r3b
protein phosphatase 2, regulatory subunit B'', beta
chr7_-_19998723 1.39 ENSDART00000173458
trip6
thyroid hormone receptor interactor 6
chr3_-_49514874 1.39 ENSDART00000167179
asf1ba
anti-silencing function 1Ba histone chaperone
chr24_-_11905911 1.39 ENSDART00000033621
tm9sf1
transmembrane 9 superfamily member 1
chr7_-_59514547 1.38 ENSDART00000168457
slx1b
SLX1 homolog B, structure-specific endonuclease subunit
chr24_-_11076400 1.37 ENSDART00000003195
chmp4c
charged multivesicular body protein 4C
chr2_+_26240631 1.37 ENSDART00000129895
palm1b
paralemmin 1b
chr15_+_23722620 1.37 ENSDART00000011447
sae1
SUMO1 activating enzyme subunit 1
chr17_-_33415740 1.37 ENSDART00000135218
ccdc28a
coiled-coil domain containing 28A
chr24_+_26140855 1.36 ENSDART00000139017
tmtopsb
teleost multiple tissue opsin b
chr18_-_45761868 1.36 ENSDART00000025423
cstf3
cleavage stimulation factor, 3' pre-RNA, subunit 3
chr5_+_25762271 1.36 ENSDART00000181323
tmem2
transmembrane protein 2
chr8_-_11834599 1.35 ENSDART00000190986
rapgef1a
Rap guanine nucleotide exchange factor (GEF) 1a
chr23_-_27235403 1.35 ENSDART00000134418
si:dkey-157g16.6
si:dkey-157g16.6
chr7_-_30624435 1.35 ENSDART00000173828
rnf111
ring finger protein 111
chr7_-_58098814 1.35 ENSDART00000147287
ENSDART00000043984
ank2b
ankyrin 2b, neuronal
chr7_-_40959667 1.32 ENSDART00000084070
rbm33a
RNA binding motif protein 33a
chr19_-_7321221 1.31 ENSDART00000092375
oxr1b
oxidation resistance 1b
chr17_-_7028418 1.31 ENSDART00000188305
ENSDART00000187895
sash1b
SAM and SH3 domain containing 1b
chr22_-_20838011 1.31 ENSDART00000186056
dot1l
DOT1-like histone H3K79 methyltransferase
chr10_+_37173029 1.31 ENSDART00000136510
ksr1a
kinase suppressor of ras 1a
chr18_+_45666489 1.31 ENSDART00000180147
ENSDART00000151351
prrg4
proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
chr19_-_20446756 1.31 ENSDART00000140711
tbc1d5
TBC1 domain family, member 5
chr17_+_33415542 1.29 ENSDART00000183169
snap23.1
synaptosomal-associated protein 23.1
chr18_+_20034023 1.29 ENSDART00000139441
morf4l1
mortality factor 4 like 1
chr2_+_26303627 1.28 ENSDART00000040278
efna2a
ephrin-A2a
chr12_-_17592215 1.28 ENSDART00000134597
usp42
ubiquitin specific peptidase 42
chr2_-_9696283 1.28 ENSDART00000165712
selenot1a
selenoprotein T, 1a
chr13_+_28580357 1.28 ENSDART00000007211
wbp1la
WW domain binding protein 1-like a
chr17_+_24597001 1.28 ENSDART00000191834
rlf
rearranged L-myc fusion
chr2_-_26596794 1.27 ENSDART00000134685
ENSDART00000056787
zgc:113691
zgc:113691

Network of associatons between targets according to the STRING database.

First level regulatory network of sox9a+sox9b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 7.9 GO:0071539 protein localization to centrosome(GO:0071539)
0.8 3.3 GO:0003228 atrial cardiac muscle tissue development(GO:0003228)
0.7 2.2 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
0.7 2.0 GO:0039015 spinal cord anterior/posterior patterning(GO:0021512) cell proliferation involved in pronephros development(GO:0039015) cell proliferation involved in kidney development(GO:0072111)
0.6 3.1 GO:0010692 regulation of alkaline phosphatase activity(GO:0010692) negative regulation of alkaline phosphatase activity(GO:0010693)
0.6 8.6 GO:0035090 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.6 1.8 GO:0005997 xylulose metabolic process(GO:0005997)
0.5 1.6 GO:0019852 L-ascorbic acid transport(GO:0015882) L-ascorbic acid metabolic process(GO:0019852)
0.5 4.0 GO:2000650 negative regulation of sodium ion transmembrane transporter activity(GO:2000650)
0.5 2.4 GO:0010481 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.5 1.4 GO:0035666 regulation of natural killer cell activation(GO:0032814) positive regulation of natural killer cell activation(GO:0032816) TRIF-dependent toll-like receptor signaling pathway(GO:0035666)
0.5 2.3 GO:0060784 regulation of cell proliferation involved in tissue homeostasis(GO:0060784)
0.5 2.3 GO:0048909 dorsal spinal cord development(GO:0021516) anterior lateral line nerve development(GO:0048909)
0.5 3.6 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.4 8.8 GO:0051098 regulation of binding(GO:0051098)
0.4 7.2 GO:0019433 triglyceride catabolic process(GO:0019433)
0.4 2.5 GO:0000393 spliceosomal conformational changes to generate catalytic conformation(GO:0000393)
0.4 2.0 GO:0035279 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.4 1.1 GO:2000434 regulation of protein neddylation(GO:2000434)
0.4 1.1 GO:0072388 FAD biosynthetic process(GO:0006747) FAD metabolic process(GO:0046443) flavin adenine dinucleotide metabolic process(GO:0072387) flavin adenine dinucleotide biosynthetic process(GO:0072388)
0.4 1.5 GO:1902745 skeletal muscle cell proliferation(GO:0014856) regulation of skeletal muscle cell proliferation(GO:0014857) positive regulation of lamellipodium organization(GO:1902745)
0.4 1.1 GO:0061355 Wnt protein secretion(GO:0061355)
0.3 1.4 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.3 3.1 GO:0006561 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.3 1.0 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.3 1.3 GO:0043968 histone H2A acetylation(GO:0043968)
0.3 2.5 GO:0070874 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.3 0.9 GO:0021698 cerebellar Purkinje cell layer structural organization(GO:0021693) cerebellar cortex structural organization(GO:0021698) U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476) nuclear polyadenylation-dependent mRNA catabolic process(GO:0071042) polyadenylation-dependent mRNA catabolic process(GO:0071047)
0.3 2.4 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.3 0.9 GO:0046833 regulation of nucleobase-containing compound transport(GO:0032239) positive regulation of nucleobase-containing compound transport(GO:0032241) positive regulation of nucleocytoplasmic transport(GO:0046824) regulation of RNA export from nucleus(GO:0046831) positive regulation of RNA export from nucleus(GO:0046833) messenger ribonucleoprotein complex assembly(GO:1990120)
0.3 1.3 GO:0036371 protein localization to T-tubule(GO:0036371)
0.3 2.4 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) positive regulation of receptor activity(GO:2000273)
0.3 1.1 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.2 1.2 GO:0000012 single strand break repair(GO:0000012)
0.2 2.4 GO:0015886 heme transport(GO:0015886) iron coordination entity transport(GO:1901678)
0.2 1.9 GO:0072425 mitotic G2 DNA damage checkpoint(GO:0007095) signal transduction involved in DNA integrity checkpoint(GO:0072401) signal transduction involved in DNA damage checkpoint(GO:0072422) signal transduction involved in G2 DNA damage checkpoint(GO:0072425)
0.2 1.3 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.2 0.7 GO:1901096 regulation of autophagosome maturation(GO:1901096)
0.2 0.6 GO:0000066 mitochondrial ornithine transport(GO:0000066) mitochondrial L-ornithine transmembrane transport(GO:1990575)
0.2 1.7 GO:0034063 stress granule assembly(GO:0034063)
0.2 1.0 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.2 2.0 GO:0006108 malate metabolic process(GO:0006108)
0.2 1.0 GO:0051031 tRNA transport(GO:0051031)
0.2 2.2 GO:0039023 pronephric duct morphogenesis(GO:0039023) nephric duct morphogenesis(GO:0072178)
0.2 2.1 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.2 0.6 GO:0010526 regulation of transposition, RNA-mediated(GO:0010525) negative regulation of transposition, RNA-mediated(GO:0010526) transposition, RNA-mediated(GO:0032197) positive regulation of neuron apoptotic process(GO:0043525) positive regulation of neuron death(GO:1901216)
0.2 1.6 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.2 1.4 GO:1901224 positive regulation of NIK/NF-kappaB signaling(GO:1901224)
0.2 1.4 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.2 2.4 GO:0051452 vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452)
0.2 2.1 GO:0051865 protein autoubiquitination(GO:0051865)
0.2 1.8 GO:0021694 cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702) cerebellar granule cell differentiation(GO:0021707)
0.2 1.1 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.2 0.8 GO:0097510 base-excision repair, AP site formation via deaminated base removal(GO:0097510)
0.2 1.1 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.2 0.6 GO:0071459 protein localization to kinetochore(GO:0034501) protein localization to chromosome, centromeric region(GO:0071459)
0.2 2.6 GO:0003382 epithelial cell morphogenesis(GO:0003382)
0.2 2.8 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.2 0.6 GO:0090113 regulation of COPII vesicle coating(GO:0003400) regulation of ER to Golgi vesicle-mediated transport by GTP hydrolysis(GO:0090113)
0.2 1.1 GO:0070073 clustering of voltage-gated calcium channels(GO:0070073)
0.1 4.2 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.1 1.3 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.1 1.4 GO:0043551 regulation of lipid kinase activity(GO:0043550) regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.1 1.5 GO:1903010 regulation of bone development(GO:1903010)
0.1 1.3 GO:0009446 putrescine biosynthetic process(GO:0009446)
0.1 1.6 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.1 2.8 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.1 1.8 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.1 1.6 GO:0099638 neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887) endosome to plasma membrane protein transport(GO:0099638) neurotransmitter receptor transport, endosome to plasma membrane(GO:0099639)
0.1 0.6 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.1 3.5 GO:0006284 base-excision repair(GO:0006284)
0.1 1.2 GO:0072386 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.1 1.2 GO:0031268 pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.1 0.3 GO:1990519 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.1 1.7 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.1 2.8 GO:0010507 negative regulation of autophagy(GO:0010507)
0.1 0.4 GO:0003322 pancreatic A cell development(GO:0003322)
0.1 0.3 GO:0050666 regulation of sulfur amino acid metabolic process(GO:0031335) regulation of homocysteine metabolic process(GO:0050666)
0.1 1.4 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.1 2.1 GO:0006198 cAMP catabolic process(GO:0006198)
0.1 1.2 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.1 3.1 GO:0016082 synaptic vesicle priming(GO:0016082)
0.1 1.3 GO:0030316 osteoclast differentiation(GO:0030316)
0.1 3.9 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.1 9.4 GO:0045930 negative regulation of mitotic cell cycle(GO:0045930)
0.1 0.6 GO:0000455 enzyme-directed rRNA pseudouridine synthesis(GO:0000455)
0.1 1.5 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.1 1.0 GO:0035677 posterior lateral line neuromast hair cell development(GO:0035677)
0.1 3.2 GO:0050821 protein stabilization(GO:0050821)
0.1 0.4 GO:0016180 snRNA processing(GO:0016180)
0.1 1.1 GO:0009303 rRNA transcription(GO:0009303)
0.1 1.2 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.1 0.6 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.1 1.0 GO:0000729 DNA double-strand break processing(GO:0000729)
0.1 1.4 GO:0015693 magnesium ion transport(GO:0015693)
0.1 0.6 GO:0097340 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.1 0.2 GO:0045299 otolith mineralization(GO:0045299)
0.1 2.4 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
0.1 0.6 GO:0071501 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.1 0.5 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1 0.7 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.1 0.3 GO:0038093 Fc receptor signaling pathway(GO:0038093)
0.1 0.2 GO:0003403 optic vesicle formation(GO:0003403)
0.1 1.7 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.1 0.6 GO:0035188 hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.1 0.7 GO:0019720 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.1 0.5 GO:2001271 regulation of execution phase of apoptosis(GO:1900117) negative regulation of execution phase of apoptosis(GO:1900118) regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1 6.3 GO:0030837 negative regulation of actin filament polymerization(GO:0030837) negative regulation of protein polymerization(GO:0032272)
0.1 0.3 GO:0051972 regulation of telomerase activity(GO:0051972)
0.1 0.5 GO:0001839 neural plate morphogenesis(GO:0001839)
0.1 1.3 GO:0042953 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.1 0.3 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.1 1.9 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.1 0.8 GO:0098734 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.1 0.4 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.1 2.6 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.1 0.7 GO:0003310 pancreatic A cell differentiation(GO:0003310)
0.1 4.4 GO:0008203 cholesterol metabolic process(GO:0008203)
0.1 0.3 GO:0034334 adherens junction maintenance(GO:0034334)
0.1 1.3 GO:0006884 cell volume homeostasis(GO:0006884)
0.1 1.3 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.0 0.7 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.4 GO:0030656 regulation of isoprenoid metabolic process(GO:0019747) regulation of vitamin metabolic process(GO:0030656) regulation of retinoic acid biosynthetic process(GO:1900052)
0.0 0.5 GO:0051156 glucose 6-phosphate metabolic process(GO:0051156)
0.0 1.2 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.0 1.1 GO:0007020 microtubule nucleation(GO:0007020)
0.0 1.5 GO:0060415 muscle tissue morphogenesis(GO:0060415)
0.0 0.8 GO:0016584 nucleosome positioning(GO:0016584)
0.0 4.7 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.0 0.2 GO:0051013 microtubule severing(GO:0051013)
0.0 0.7 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.2 GO:0030224 monocyte differentiation(GO:0030224)
0.0 1.8 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 2.5 GO:0015914 phospholipid transport(GO:0015914)
0.0 1.1 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.3 GO:0021628 olfactory nerve development(GO:0021553) olfactory nerve morphogenesis(GO:0021627) olfactory nerve formation(GO:0021628)
0.0 1.7 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.5 GO:0045116 protein neddylation(GO:0045116)
0.0 3.8 GO:0017148 negative regulation of translation(GO:0017148)
0.0 0.6 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.9 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 2.5 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.7 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.1 GO:0015722 canalicular bile acid transport(GO:0015722) bile acid secretion(GO:0032782)
0.0 3.6 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.5 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.6 GO:0035329 hippo signaling(GO:0035329)
0.0 1.4 GO:0031123 RNA 3'-end processing(GO:0031123)
0.0 1.4 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.0 0.2 GO:0097107 postsynaptic density assembly(GO:0097107) modulation of excitatory postsynaptic potential(GO:0098815) positive regulation of excitatory postsynaptic potential(GO:2000463)
0.0 0.3 GO:0050667 homocysteine metabolic process(GO:0050667)
0.0 1.4 GO:0099515 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.0 0.6 GO:0060541 respiratory system development(GO:0060541)
0.0 0.3 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 1.4 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.8 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.1 GO:0060829 negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060829)
0.0 2.4 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 1.3 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800)
0.0 0.3 GO:0051601 exocyst localization(GO:0051601)
0.0 2.6 GO:0032147 activation of protein kinase activity(GO:0032147)
0.0 0.6 GO:0032786 positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.0 0.0 GO:0071421 manganese ion transmembrane transport(GO:0071421)
0.0 1.3 GO:0030901 midbrain development(GO:0030901)
0.0 0.2 GO:0006622 protein targeting to lysosome(GO:0006622) protein retention in Golgi apparatus(GO:0045053)
0.0 0.5 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.1 GO:0055107 Golgi to secretory granule transport(GO:0055107)
0.0 1.4 GO:0045786 negative regulation of cell cycle(GO:0045786)
0.0 0.9 GO:0009948 anterior/posterior axis specification(GO:0009948)
0.0 0.8 GO:0006694 steroid biosynthetic process(GO:0006694)
0.0 0.5 GO:0099518 vesicle cytoskeletal trafficking(GO:0099518)
0.0 0.6 GO:0006688 glycosphingolipid biosynthetic process(GO:0006688)
0.0 1.4 GO:0006081 cellular aldehyde metabolic process(GO:0006081)
0.0 0.5 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.9 GO:0034968 histone lysine methylation(GO:0034968)
0.0 0.5 GO:0001843 neural tube closure(GO:0001843)
0.0 5.1 GO:0007018 microtubule-based movement(GO:0007018)
0.0 0.5 GO:0051289 protein homotetramerization(GO:0051289)
0.0 0.1 GO:0090387 phagosome maturation involved in apoptotic cell clearance(GO:0090386) phagolysosome assembly involved in apoptotic cell clearance(GO:0090387)
0.0 0.4 GO:0031398 positive regulation of protein ubiquitination(GO:0031398)
0.0 0.6 GO:0048264 determination of ventral identity(GO:0048264)
0.0 1.1 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 0.3 GO:0072576 liver morphogenesis(GO:0072576)
0.0 0.2 GO:0035860 esophagus smooth muscle contraction(GO:0014846) glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0 0.3 GO:0006743 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.9 GO:0001764 neuron migration(GO:0001764)
0.0 0.1 GO:0030242 pexophagy(GO:0030242)
0.0 0.2 GO:0032204 regulation of telomere maintenance(GO:0032204)
0.0 0.4 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.6 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 0.7 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 0.2 GO:0016233 telomere capping(GO:0016233)
0.0 1.5 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.0 0.2 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.0 0.8 GO:0060048 cardiac muscle contraction(GO:0060048)
0.0 0.2 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.0 1.5 GO:0006909 phagocytosis(GO:0006909)
0.0 2.7 GO:0006869 lipid transport(GO:0006869)
0.0 0.8 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 0.2 GO:0046520 sphingoid biosynthetic process(GO:0046520)
0.0 0.9 GO:0061640 cytoskeleton-dependent cytokinesis(GO:0061640)
0.0 1.1 GO:0006979 response to oxidative stress(GO:0006979)
0.0 1.6 GO:0016579 protein deubiquitination(GO:0016579)
0.0 0.1 GO:0006693 prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693)
0.0 0.5 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 0.1 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 2.0 GO:0000377 RNA splicing, via transesterification reactions(GO:0000375) RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.0 0.9 GO:0048232 spermatogenesis(GO:0007283) male gamete generation(GO:0048232)
0.0 0.2 GO:0043113 receptor clustering(GO:0043113)
0.0 0.1 GO:0051597 response to methylmercury(GO:0051597)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0097189 apoptotic body(GO:0097189)
0.6 1.9 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.6 8.0 GO:0034361 very-low-density lipoprotein particle(GO:0034361)
0.5 3.6 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.5 1.4 GO:0030062 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.4 2.5 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006) catalytic step 1 spliceosome(GO:0071012)
0.4 3.3 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.4 1.1 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.4 2.1 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.4 1.1 GO:0031213 RSF complex(GO:0031213)
0.3 1.4 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.3 2.0 GO:0005845 mRNA cap binding complex(GO:0005845)
0.3 1.9 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.3 1.6 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.3 0.9 GO:0042382 paraspeckles(GO:0042382)
0.2 2.4 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.2 1.4 GO:0033557 Slx1-Slx4 complex(GO:0033557)
0.2 1.1 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.2 3.8 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.2 2.4 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.2 3.9 GO:0032039 integrator complex(GO:0032039)
0.2 1.6 GO:0045240 dihydrolipoyl dehydrogenase complex(GO:0045240)
0.2 1.5 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.2 0.6 GO:0000818 nuclear MIS12/MIND complex(GO:0000818)
0.2 0.5 GO:0097361 CIA complex(GO:0097361)
0.1 1.2 GO:0035145 exon-exon junction complex(GO:0035145)
0.1 0.6 GO:0070209 ASTRA complex(GO:0070209)
0.1 0.8 GO:0016589 NURF complex(GO:0016589)
0.1 0.9 GO:0043194 axon initial segment(GO:0043194)
0.1 0.7 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.1 0.7 GO:0019008 molybdopterin synthase complex(GO:0019008)
0.1 0.8 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.1 1.7 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 0.4 GO:0016460 myosin II complex(GO:0016460)
0.1 1.3 GO:0016580 Sin3 complex(GO:0016580)
0.1 0.5 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.1 2.4 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.1 2.3 GO:0034399 nuclear periphery(GO:0034399)
0.1 1.4 GO:0000815 ESCRT III complex(GO:0000815)
0.1 1.0 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.1 2.2 GO:0071565 nBAF complex(GO:0071565)
0.1 1.3 GO:0030315 T-tubule(GO:0030315)
0.1 8.5 GO:0016607 nuclear speck(GO:0016607)
0.1 9.3 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.1 0.6 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024) nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.1 6.1 GO:0005871 kinesin complex(GO:0005871)
0.1 2.6 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 1.6 GO:0035102 PRC1 complex(GO:0035102)
0.1 0.5 GO:0071546 pi-body(GO:0071546)
0.1 0.7 GO:0042575 DNA polymerase complex(GO:0042575)
0.1 3.6 GO:0000313 organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.0 1.0 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 1.9 GO:0031970 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 0.3 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.8 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.9 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 4.0 GO:0031201 SNARE complex(GO:0031201)
0.0 1.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 1.6 GO:1903293 protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.0 0.4 GO:0070652 HAUS complex(GO:0070652)
0.0 3.7 GO:0005795 Golgi stack(GO:0005795)
0.0 2.3 GO:0032432 actin filament bundle(GO:0032432)
0.0 0.3 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.3 GO:0071797 LUBAC complex(GO:0071797)
0.0 1.3 GO:0016605 PML body(GO:0016605)
0.0 0.6 GO:0031209 SCAR complex(GO:0031209)
0.0 0.5 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.7 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 1.0 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.1 GO:0034271 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 0.9 GO:0000776 kinetochore(GO:0000776)
0.0 0.6 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 2.4 GO:0005814 centriole(GO:0005814)
0.0 0.3 GO:0000176 nuclear exosome (RNase complex)(GO:0000176) cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.5 GO:0000784 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783) nuclear chromosome, telomeric region(GO:0000784)
0.0 2.3 GO:0000786 nucleosome(GO:0000786)
0.0 1.2 GO:0005776 autophagosome(GO:0005776)
0.0 0.8 GO:0032156 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.2 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 2.6 GO:0000793 condensed chromosome(GO:0000793)
0.0 0.4 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.7 GO:0005861 troponin complex(GO:0005861)
0.0 29.5 GO:0005576 extracellular region(GO:0005576)
0.0 1.3 GO:0043197 dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.0 1.0 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.8 GO:0008021 synaptic vesicle(GO:0008021)
0.0 0.1 GO:0033186 CAF-1 complex(GO:0033186)
0.0 2.4 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 1.4 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 0.9 GO:0030027 lamellipodium(GO:0030027)
0.0 2.0 GO:0005774 vacuolar membrane(GO:0005774)
0.0 0.5 GO:0005770 late endosome(GO:0005770)
0.0 0.3 GO:0031941 filamentous actin(GO:0031941)
0.0 1.4 GO:0016459 myosin complex(GO:0016459)
0.0 0.7 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 1.1 GO:0030658 transport vesicle membrane(GO:0030658)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 8.0 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
0.8 3.8 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309) double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.7 2.2 GO:1990825 mRNA CDS binding(GO:1990715) sequence-specific mRNA binding(GO:1990825)
0.7 7.2 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.6 3.1 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.6 4.2 GO:0000995 transcription factor activity, core RNA polymerase III binding(GO:0000995)
0.5 2.2 GO:0071889 14-3-3 protein binding(GO:0071889)
0.5 2.0 GO:0070883 pre-miRNA binding(GO:0070883)
0.5 2.0 GO:0004471 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.5 4.0 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.5 2.8 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.5 1.4 GO:0008022 protein C-terminus binding(GO:0008022)
0.4 1.3 GO:0032184 SUMO polymer binding(GO:0032184)
0.4 1.3 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.4 1.7 GO:0005521 lamin binding(GO:0005521)
0.4 1.7 GO:0070513 death domain binding(GO:0070513)
0.4 2.0 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.4 1.2 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.4 2.7 GO:0030274 LIM domain binding(GO:0030274)
0.4 1.1 GO:0003919 FMN adenylyltransferase activity(GO:0003919)
0.4 1.1 GO:0043878 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity(GO:0043878)
0.3 1.0 GO:0072590 N-acetyl-L-aspartate-L-glutamate ligase activity(GO:0072590) citrate-L-glutamate ligase activity(GO:0072591)
0.3 3.3 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.3 2.6 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.3 1.3 GO:0031151 histone methyltransferase activity (H3-K79 specific)(GO:0031151)
0.3 2.3 GO:0070888 E-box binding(GO:0070888)
0.3 3.1 GO:0016889 endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
0.3 1.2 GO:0043998 H2A histone acetyltransferase activity(GO:0043998)
0.3 2.4 GO:0015232 heme transporter activity(GO:0015232)
0.3 1.9 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.3 1.9 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.3 1.6 GO:0004594 pantothenate kinase activity(GO:0004594)
0.3 0.8 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.2 4.3 GO:0002039 p53 binding(GO:0002039)
0.2 7.0 GO:0019003 GDP binding(GO:0019003)
0.2 0.6 GO:0008489 UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity(GO:0008489)
0.2 1.2 GO:0008118 N-acetyllactosaminide alpha-2,3-sialyltransferase activity(GO:0008118)
0.2 0.5 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.2 1.5 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.2 2.4 GO:0051117 ATPase binding(GO:0051117)
0.2 1.1 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.2 1.2 GO:0005351 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.2 1.1 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.1 1.9 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 1.4 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.1 1.3 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.1 1.8 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 4.0 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.1 1.1 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.1 0.7 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.1 3.1 GO:0015248 sterol transporter activity(GO:0015248)
0.1 0.3 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.1 0.4 GO:0032038 myosin head/neck binding(GO:0032028) myosin II head/neck binding(GO:0032034) myosin II heavy chain binding(GO:0032038)
0.1 1.0 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.1 3.0 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.1 1.4 GO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor(GO:0016624)
0.1 1.0 GO:0005522 profilin binding(GO:0005522)
0.1 2.4 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 2.2 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 1.0 GO:0031013 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.1 0.4 GO:0008905 mannose-1-phosphate guanylyltransferase activity(GO:0004475) mannose-phosphate guanylyltransferase activity(GO:0008905)
0.1 1.4 GO:0051879 Hsp90 protein binding(GO:0051879)
0.1 2.1 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 0.3 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.1 1.7 GO:0016229 steroid dehydrogenase activity(GO:0016229)
0.1 0.6 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.1 0.5 GO:0005536 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) glucose binding(GO:0005536) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 1.8 GO:0015299 solute:proton antiporter activity(GO:0015299)
0.1 0.9 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 1.2 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.1 0.4 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 0.4 GO:0050699 WW domain binding(GO:0050699)
0.1 0.3 GO:0030586 [methionine synthase] reductase activity(GO:0030586)
0.1 6.0 GO:0003777 microtubule motor activity(GO:0003777)
0.1 1.4 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 0.9 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.1 1.3 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.1 0.6 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.1 1.0 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.1 0.3 GO:0004122 cystathionine beta-synthase activity(GO:0004122)
0.1 4.2 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 0.4 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 9.3 GO:0003713 transcription coactivator activity(GO:0003713)
0.1 0.3 GO:0048156 tau protein binding(GO:0048156)
0.1 1.1 GO:0097602 cullin family protein binding(GO:0097602)
0.1 1.1 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 1.3 GO:0015377 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.1 0.9 GO:0010181 FMN binding(GO:0010181)
0.1 3.3 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 3.1 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 1.1 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 2.5 GO:0017124 SH3 domain binding(GO:0017124)
0.0 1.0 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 1.5 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.1 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0 1.7 GO:0005109 frizzled binding(GO:0005109)
0.0 0.3 GO:0048039 ubiquinone binding(GO:0048039)
0.0 0.8 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.2 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.0 1.2 GO:0003684 damaged DNA binding(GO:0003684)
0.0 0.6 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 1.2 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 1.1 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.2 GO:0030504 inorganic diphosphate transmembrane transporter activity(GO:0030504)
0.0 6.3 GO:0042393 histone binding(GO:0042393)
0.0 0.6 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.2 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.1 GO:0015126 canalicular bile acid transmembrane transporter activity(GO:0015126) bile acid-exporting ATPase activity(GO:0015432)
0.0 0.6 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.6 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.7 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.2 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 1.3 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.3 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 1.4 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.1 GO:0033842 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity(GO:0033842)
0.0 1.4 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.2 GO:0017040 ceramidase activity(GO:0017040)
0.0 9.7 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.1 GO:0098639 C-X3-C chemokine binding(GO:0019960) protein binding involved in cell-matrix adhesion(GO:0098634) collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 8.2 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 2.3 GO:0004519 endonuclease activity(GO:0004519)
0.0 0.9 GO:0008013 beta-catenin binding(GO:0008013)
0.0 3.9 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 2.8 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor(GO:0016616)
0.0 0.2 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.1 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.0 1.0 GO:0009055 electron carrier activity(GO:0009055)
0.0 0.6 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.5 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.3 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.4 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.2 GO:0052795 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 0.4 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.4 GO:0004698 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.0 2.4 GO:0008134 transcription factor binding(GO:0008134)
0.0 0.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.1 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 1.3 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.5 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.4 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.6 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.2 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 1.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 2.1 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 0.1 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.3 GO:0008378 galactosyltransferase activity(GO:0008378)
0.0 3.4 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.2 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 4.1 GO:0061630 ubiquitin protein ligase activity(GO:0061630)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 7.5 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.4 8.0 PID REELIN PATHWAY Reelin signaling pathway
0.2 5.8 PID EPHB FWD PATHWAY EPHB forward signaling
0.2 1.0 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.2 1.5 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 6.8 PID TNF PATHWAY TNF receptor signaling pathway
0.1 5.4 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.1 3.5 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.1 0.6 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.1 2.7 PID NETRIN PATHWAY Netrin-mediated signaling events
0.1 3.0 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.1 0.7 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.1 1.4 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 1.5 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.1 3.5 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.1 1.1 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.1 1.0 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.1 5.4 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.1 4.0 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.1 1.0 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 1.6 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.1 1.6 PID MYC PATHWAY C-MYC pathway
0.1 2.2 PID MTOR 4PATHWAY mTOR signaling pathway
0.1 1.1 PID AURORA A PATHWAY Aurora A signaling
0.1 1.4 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.1 1.3 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.9 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.4 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.3 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.6 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 1.2 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.4 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.2 PID ALK2 PATHWAY ALK2 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 6.5 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.4 5.0 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.3 3.1 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.3 1.0 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.2 1.2 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.2 3.6 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.2 1.5 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.2 1.4 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.2 1.1 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.2 1.9 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS Genes involved in CREB phosphorylation through the activation of Ras
0.1 1.6 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 2.4 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.1 6.0 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 1.4 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.1 2.2 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 2.1 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 1.9 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 1.9 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1 1.4 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.1 3.3 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.1 1.7 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 2.1 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 0.6 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 1.7 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.1 0.6 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 3.4 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 0.9 REACTOME INTEGRATION OF ENERGY METABOLISM Genes involved in Integration of energy metabolism
0.1 1.3 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 1.4 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.6 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 1.5 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 1.5 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 0.3 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.9 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0 1.7 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.2 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.3 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.8 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.5 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 2.3 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.6 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.0 1.7 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.3 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.6 REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.0 0.2 REACTOME SIGNALING BY ERBB2 Genes involved in Signaling by ERBB2
0.0 0.7 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0 0.6 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.7 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.3 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 1.1 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.0 0.2 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.4 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.8 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events