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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for sp1

Z-value: 2.23

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Transcription factors associated with sp1

Gene Symbol Gene ID Gene Info
sp1
ENSDARG00000088347 sp1 transcription factor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
sp1dr11_v1_chr11_-_27821_279030.963.5e-10Click!

Activity profile of sp1 motif

Sorted Z-values of sp1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr13_-_17860307 10.99 ENSDART00000135920
ENSDART00000054579
march8
membrane-associated ring finger (C3HC4) 8
chr8_-_410728 9.55 ENSDART00000151255
trim36
tripartite motif containing 36
chr18_-_127558 8.96 ENSDART00000149556
trpm7
transient receptor potential cation channel, subfamily M, member 7
chr8_-_410199 7.29 ENSDART00000091177
ENSDART00000122979
ENSDART00000151331
ENSDART00000151155
trim36
tripartite motif containing 36
chr18_-_127873 6.80 ENSDART00000148490
trpm7
transient receptor potential cation channel, subfamily M, member 7
chr8_-_20230559 6.22 ENSDART00000193677
mllt1a
MLLT1, super elongation complex subunit a
chr7_-_19332293 6.06 ENSDART00000169668
ENSDART00000137575
ENSDART00000090406
dock11
dedicator of cytokinesis 11
chr3_+_51684963 6.01 ENSDART00000091180
ENSDART00000183711
ENSDART00000159493
baiap2a
BAI1-associated protein 2a
chr16_-_7793457 5.86 ENSDART00000113483
trim71
tripartite motif containing 71, E3 ubiquitin protein ligase
chr17_-_23709347 5.80 ENSDART00000124661
papss2a
3'-phosphoadenosine 5'-phosphosulfate synthase 2a
chr2_+_35603637 5.78 ENSDART00000147278
plk3
polo-like kinase 3 (Drosophila)
chr7_+_38349667 5.75 ENSDART00000010046
rhpn2
rhophilin, Rho GTPase binding protein 2
chr6_+_3334392 5.67 ENSDART00000133707
ENSDART00000130879
st3gal3a
ST3 beta-galactoside alpha-2,3-sialyltransferase 3a
chr20_-_182841 5.64 ENSDART00000064546
si:ch211-241j12.3
si:ch211-241j12.3
chr17_+_25856671 5.63 ENSDART00000064817
wapla
WAPL cohesin release factor a
chr25_+_3104959 5.62 ENSDART00000167130
rab3il1
RAB3A interacting protein (rabin3)-like 1
chr5_-_54395488 5.40 ENSDART00000160781
zmynd19
zinc finger, MYND-type containing 19
chr23_-_31645760 5.36 ENSDART00000035031
sgk1
serum/glucocorticoid regulated kinase 1
chr12_-_35505610 5.32 ENSDART00000105518
camk2g1
calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma 1
chr8_-_20230802 5.29 ENSDART00000063400
mllt1a
MLLT1, super elongation complex subunit a
chr7_-_48251234 5.26 ENSDART00000024062
ENSDART00000098904
cpeb1b
cytoplasmic polyadenylation element binding protein 1b
chr19_+_26340736 5.08 ENSDART00000013497
mylipa
myosin regulatory light chain interacting protein a
chr19_-_867071 5.08 ENSDART00000122257
eomesa
eomesodermin homolog a
chr6_+_27991943 5.06 ENSDART00000143974
ENSDART00000141354
ENSDART00000088914
ENSDART00000139367
amotl2a
angiomotin like 2a
chr6_+_32326074 4.99 ENSDART00000042134
ENSDART00000181177
dock7
dedicator of cytokinesis 7
chr5_-_13086616 4.98 ENSDART00000051664
ypel1
yippee-like 1
chr23_-_45955177 4.92 ENSDART00000165963
ENSDART00000186649
ENSDART00000185773
LO017850.1

chr12_+_46634736 4.79 ENSDART00000008009
trim16
tripartite motif containing 16
chr23_+_2740741 4.75 ENSDART00000134938
zgc:114123
zgc:114123
chr6_-_1820606 4.75 ENSDART00000183228
FO834857.1

chr10_-_2942900 4.68 ENSDART00000002622
oclna
occludin a
chr7_+_44802353 4.67 ENSDART00000066380
ca7
carbonic anhydrase VII
chr19_+_30867845 4.67 ENSDART00000047461
mfsd2ab
major facilitator superfamily domain containing 2ab
chr17_-_50071748 4.66 ENSDART00000075188
zgc:113886
zgc:113886
chr19_-_11031145 4.59 ENSDART00000151375
ENSDART00000027598
ENSDART00000137865
ENSDART00000188025
tpm3
tropomyosin 3
chr7_+_1473929 4.56 ENSDART00000050687
lpcat4
lysophosphatidylcholine acyltransferase 4
chr19_-_2029777 4.54 ENSDART00000128639
CABZ01071939.1

chr15_+_29025090 4.41 ENSDART00000131755
si:ch211-137a8.2
si:ch211-137a8.2
chr8_-_38022298 4.40 ENSDART00000067809
rab11fip1a
RAB11 family interacting protein 1 (class I) a
chr13_+_45582391 4.39 ENSDART00000058093
ldlrap1b
low density lipoprotein receptor adaptor protein 1b
chr17_+_12075805 4.36 ENSDART00000155329
cnsta
consortin, connexin sorting protein a
chr13_+_1100197 4.35 ENSDART00000139560
ppp3r1a
protein phosphatase 3, regulatory subunit B, alpha a
chr17_+_14965570 4.34 ENSDART00000066604
gpr137c
G protein-coupled receptor 137c
chr16_-_29387215 4.28 ENSDART00000148787
s100a1
S100 calcium binding protein A1
chr22_+_336256 4.26 ENSDART00000019155
btg2
B-cell translocation gene 2
chr2_+_23006792 4.22 ENSDART00000027782
mknk2a
MAP kinase interacting serine/threonine kinase 2a
chr4_-_4256300 4.22 ENSDART00000103319
ENSDART00000150279
cd9b
CD9 molecule b
chr20_+_39250673 4.20 ENSDART00000153003
reps1
RALBP1 associated Eps domain containing 1
chr25_+_22319940 4.17 ENSDART00000154065
ENSDART00000153492
ENSDART00000024866
ENSDART00000154376
cyp11a1
cytochrome P450, family 11, subfamily A, polypeptide 1
chr10_-_244745 4.17 ENSDART00000136551
klhl35
kelch-like family member 35
chr15_+_29024895 4.17 ENSDART00000141164
ENSDART00000144126
si:ch211-137a8.2
si:ch211-137a8.2
chr7_+_7630409 4.15 ENSDART00000172934
clcn3
chloride channel 3
chr21_-_43398457 4.13 ENSDART00000166530
ccni2
cyclin I family, member 2
chr21_-_30293224 4.12 ENSDART00000101051
slbp2
stem-loop binding protein 2
chr12_-_37449396 4.05 ENSDART00000152951
cdc42ep4b
CDC42 effector protein (Rho GTPase binding) 4b
chr14_-_15763648 4.05 ENSDART00000160712
dusp1
dual specificity phosphatase 1
chr20_+_51061695 4.04 ENSDART00000134416
im:7140055
im:7140055
chr3_-_15470944 4.03 ENSDART00000185302
spns1
spinster homolog 1 (Drosophila)
chr4_-_1720648 4.01 ENSDART00000103484
gas2l3
growth arrest-specific 2 like 3
chr15_-_25435085 4.01 ENSDART00000112079
tlcd2
TLC domain containing 2
chr23_-_10175898 4.00 ENSDART00000146185
krt5
keratin 5
chr6_+_12503849 3.94 ENSDART00000149529
stk24b
serine/threonine kinase 24b (STE20 homolog, yeast)
chr3_-_15131438 3.94 ENSDART00000131720
xpo6
exportin 6
chr2_+_25658112 3.92 ENSDART00000051234
tnika
TRAF2 and NCK interacting kinase a
chr7_-_4125021 3.91 ENSDART00000167182
ENSDART00000173696
zgc:55733
zgc:55733
chr3_-_32362872 3.90 ENSDART00000035545
ENSDART00000012630
prmt1
protein arginine methyltransferase 1
chr23_+_2825940 3.82 ENSDART00000135781
plcg1
phospholipase C, gamma 1
chr9_+_2452672 3.81 ENSDART00000193993
chn1
chimerin 1
chr19_+_20201254 3.73 ENSDART00000010140
igf2bp3
insulin-like growth factor 2 mRNA binding protein 3
chr2_-_47620806 3.69 ENSDART00000038228
ap1s3b
adaptor-related protein complex 1, sigma 3 subunit, b
chr5_-_54714525 3.68 ENSDART00000150138
ENSDART00000150070
ccnb1
cyclin B1
chr3_+_29082267 3.67 ENSDART00000145615
cacna1i
calcium channel, voltage-dependent, T type, alpha 1I subunit
chr15_+_11644866 3.65 ENSDART00000188716
slc1a5
solute carrier family 1 (neutral amino acid transporter), member 5
chr10_+_39199547 3.63 ENSDART00000075943
ei24
etoposide induced 2.4
chr5_-_54714789 3.62 ENSDART00000063357
ccnb1
cyclin B1
chr23_+_35426404 3.60 ENSDART00000164658
si:ch211-225h24.2
si:ch211-225h24.2
chr2_-_52550135 3.49 ENSDART00000044411
gna11b
guanine nucleotide binding protein (G protein), alpha 11b (Gq class)
chr21_-_43398122 3.46 ENSDART00000050533
ccni2
cyclin I family, member 2
chr20_+_26940178 3.45 ENSDART00000190888
cdca4
cell division cycle associated 4
chr15_+_46853252 3.45 ENSDART00000186040
zgc:153039
zgc:153039
chr4_-_77551860 3.45 ENSDART00000188176
AL935186.6

chr22_+_883678 3.44 ENSDART00000140588
stk38b
serine/threonine kinase 38b
chr16_-_26820634 3.43 ENSDART00000111156
pdp1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr17_+_51746830 3.42 ENSDART00000184230
odc1
ornithine decarboxylase 1
chr8_+_11687254 3.42 ENSDART00000042040
atp2a2a
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2a
chr2_+_44512324 3.41 ENSDART00000155017
ENSDART00000156310
ENSDART00000156686
pask
PAS domain containing serine/threonine kinase
chr10_-_25217347 3.36 ENSDART00000036906
kpna7
karyopherin alpha 7 (importin alpha 8)
chr2_+_25657958 3.35 ENSDART00000161407
tnika
TRAF2 and NCK interacting kinase a
chr2_-_58075414 3.35 ENSDART00000161920
nectin4
nectin cell adhesion molecule 4
chr11_-_43226255 3.34 ENSDART00000172929
sptbn1
spectrin, beta, non-erythrocytic 1
chr6_+_41503854 3.34 ENSDART00000136538
ENSDART00000140108
ENSDART00000084861
cish
cytokine inducible SH2-containing protein
chr17_-_2578026 3.31 ENSDART00000065821
zp3.2
zona pellucida glycoprotein 3, tandem duplicate 2
chr21_+_34122801 3.29 ENSDART00000182627
hmgb3b
high mobility group box 3b
chr16_-_8120203 3.27 ENSDART00000193430
snrka
SNF related kinase a
chr25_+_7492663 3.27 ENSDART00000166496
cat
catalase
chr14_+_32926385 3.25 ENSDART00000139159
lnx2b
ligand of numb-protein X 2b
chr9_-_46415847 3.22 ENSDART00000009790
cx43.4
connexin 43.4
chr7_-_45852270 3.22 ENSDART00000170224
shcbp1
SHC SH2-domain binding protein 1
chr9_-_11263228 3.21 ENSDART00000113847
chpfa
chondroitin polymerizing factor a
chr9_-_34269066 3.20 ENSDART00000059955
ildr1b
immunoglobulin-like domain containing receptor 1b
chr3_-_34547000 3.18 ENSDART00000166623
sept9a
septin 9a
chr21_-_39024754 3.18 ENSDART00000056878
traf4b
tnf receptor-associated factor 4b
chr19_+_28291062 3.15 ENSDART00000163382
lpcat1
lysophosphatidylcholine acyltransferase 1
chr18_+_3243292 3.14 ENSDART00000166580
pak1
p21 protein (Cdc42/Rac)-activated kinase 1
chr17_-_2584423 3.13 ENSDART00000013506
zp3.2
zona pellucida glycoprotein 3, tandem duplicate 2
chr20_-_28698172 3.12 ENSDART00000190635
sipa1l1
signal-induced proliferation-associated 1 like 1
chr15_+_47582207 3.12 ENSDART00000159388
CABZ01087566.1

chr10_-_22150419 3.12 ENSDART00000006173
cldn7b
claudin 7b
chr22_+_835728 3.11 ENSDART00000003325
dennd2db
DENN/MADD domain containing 2Db
chr9_-_32343673 3.10 ENSDART00000078499
rftn2
raftlin family member 2
chr14_+_30291611 3.10 ENSDART00000173004
mtus1a
microtubule associated tumor suppressor 1a
chr23_-_32236122 3.10 ENSDART00000103343
grasp
GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein
chr3_+_15776446 3.08 ENSDART00000146651
znf652
zinc finger protein 652
chr1_+_45707219 3.08 ENSDART00000143363
si:ch211-214c7.4
si:ch211-214c7.4
chr1_+_44196236 3.08 ENSDART00000179560
ENSDART00000166324
ctnnd1
catenin (cadherin-associated protein), delta 1
chr2_+_59015878 3.07 ENSDART00000148816
ENSDART00000122795
si:ch1073-391i24.1
si:ch1073-391i24.1
chr13_+_49727333 3.05 ENSDART00000168799
ENSDART00000037559
ggps1
geranylgeranyl diphosphate synthase 1
chr24_+_35387517 3.04 ENSDART00000058571
snai2
snail family zinc finger 2
chr3_-_30909487 3.04 ENSDART00000025046
ppp1caa
protein phosphatase 1, catalytic subunit, alpha isozyme a
chr18_-_3527686 3.02 ENSDART00000169049
capn5a
calpain 5a
chr17_+_4368859 3.02 ENSDART00000055385
crls1
cardiolipin synthase 1
chr20_+_46741074 3.01 ENSDART00000145294
si:ch211-57i17.1
si:ch211-57i17.1
chr24_+_24086249 3.00 ENSDART00000002953
lipib
lipase, member Ib
chr23_+_36306539 2.96 ENSDART00000053267
hnrnpa1b
heterogeneous nuclear ribonucleoprotein A1b
chr13_+_421231 2.95 ENSDART00000188212
ENSDART00000017854
lgi1a
leucine-rich, glioma inactivated 1a
chr7_+_67325933 2.94 ENSDART00000170575
ENSDART00000183342
nfat5b
nuclear factor of activated T cells 5b
chr15_-_25094026 2.94 ENSDART00000129154
exo5
exonuclease 5
chr19_-_6193448 2.94 ENSDART00000151405
erf
Ets2 repressor factor
chr6_+_21005725 2.93 ENSDART00000041370
cx44.2
connexin 44.2
chr6_+_38626684 2.93 ENSDART00000086533
atp10a
ATPase phospholipid transporting 10A
chr16_+_25259313 2.92 ENSDART00000058938
fbxo32
F-box protein 32
chr11_+_31324335 2.92 ENSDART00000088093
sipa1l2
signal-induced proliferation-associated 1 like 2
chr13_-_24218795 2.90 ENSDART00000136217
galnt2
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2
chr3_+_43102010 2.89 ENSDART00000162096
micall2a
mical-like 2a
chr20_+_4157815 2.87 ENSDART00000113132
gnpat
glyceronephosphate O-acyltransferase
chr19_+_14352332 2.83 ENSDART00000164386
arid1ab
AT rich interactive domain 1Ab (SWI-like)
chr7_+_10701938 2.83 ENSDART00000158162
arnt2
aryl-hydrocarbon receptor nuclear translocator 2
chr1_-_40102836 2.82 ENSDART00000147317
cntf
ciliary neurotrophic factor
chr8_-_4618653 2.82 ENSDART00000025535
sept5a
septin 5a
chr20_-_53949798 2.82 ENSDART00000153435
ppp2r5cb
protein phosphatase 2, regulatory subunit B', gamma b
chr3_-_61494840 2.81 ENSDART00000101957
baiap2l1b
BAI1-associated protein 2-like 1b
chr16_-_41667101 2.80 ENSDART00000084528
atp2c1
ATPase secretory pathway Ca2+ transporting 1
chr6_-_7776612 2.80 ENSDART00000190269
myh9a
myosin, heavy chain 9a, non-muscle
chr22_+_11756040 2.79 ENSDART00000105808
krt97
keratin 97
chr7_+_24881680 2.77 ENSDART00000058843
krcp
kelch repeat-containing protein
chr4_-_77563411 2.76 ENSDART00000186841
AL935186.8

chr12_-_25380028 2.76 ENSDART00000142674
zfp36l2
zinc finger protein 36, C3H type-like 2
chr22_-_17688868 2.74 ENSDART00000012336
ENSDART00000147070
tjp3
tight junction protein 3
chr3_-_6417328 2.74 ENSDART00000160979
jpt1b
Jupiter microtubule associated homolog 1b
chr13_+_11829072 2.73 ENSDART00000079356
ENSDART00000170160
sufu
suppressor of fused homolog (Drosophila)
chr19_-_23227582 2.71 ENSDART00000042172
grb10a
growth factor receptor-bound protein 10a
chr3_+_34986837 2.71 ENSDART00000190341
smarce1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
chr15_-_45538773 2.71 ENSDART00000113494
MB21D2
Mab-21 domain containing 2
chr22_-_34979139 2.71 ENSDART00000116455
ENSDART00000133537
arhgap19
Rho GTPase activating protein 19
chr15_+_12435975 2.70 ENSDART00000168011
tmprss4a
transmembrane protease, serine 4a
chr15_+_40188076 2.70 ENSDART00000063779
efhd1
EF-hand domain family, member D1
chr18_+_27337994 2.69 ENSDART00000136172
si:dkey-29p10.4
si:dkey-29p10.4
chr9_+_22780901 2.69 ENSDART00000110992
ENSDART00000143972
rif1
replication timing regulatory factor 1
chr8_+_2656231 2.69 ENSDART00000160833
fam102aa
family with sequence similarity 102, member Aa
chr15_+_12436220 2.68 ENSDART00000169894
tmprss4a
transmembrane protease, serine 4a
chr2_-_39675829 2.68 ENSDART00000147821
spsb4a
splA/ryanodine receptor domain and SOCS box containing 4a
chr1_+_46493944 2.67 ENSDART00000114083
mcf2la
mcf.2 cell line derived transforming sequence-like a
chr20_-_10487951 2.65 ENSDART00000064112
glrx5
glutaredoxin 5 homolog (S. cerevisiae)
chr13_+_47821524 2.65 ENSDART00000109978
zc3h6
zinc finger CCCH-type containing 6
chr8_+_2656681 2.64 ENSDART00000185067
ENSDART00000165943
fam102aa
family with sequence similarity 102, member Aa
chr20_-_1635922 2.61 ENSDART00000181502
CR846082.1

chr15_-_25093680 2.60 ENSDART00000062695
exo5
exonuclease 5
chr3_-_36440705 2.60 ENSDART00000162875
rogdi
rogdi homolog (Drosophila)
chr10_-_35257458 2.60 ENSDART00000143890
ENSDART00000139107
ENSDART00000082445
prr11
proline rich 11
chr12_-_4475890 2.58 ENSDART00000092492
si:ch211-173d10.1
si:ch211-173d10.1
chr12_+_14149686 2.58 ENSDART00000123741
kbtbd2
kelch repeat and BTB (POZ) domain containing 2
chr3_-_60589292 2.58 ENSDART00000157822
jmjd6
jumonji domain containing 6
chr18_+_46151505 2.57 ENSDART00000015034
ENSDART00000141287
blvrb
biliverdin reductase B
chr18_+_38774584 2.57 ENSDART00000129750
fam214a
family with sequence similarity 214, member A
chr19_-_6193067 2.56 ENSDART00000092656
ENSDART00000140347
erf
Ets2 repressor factor
chr7_-_64971839 2.56 ENSDART00000164682
sinhcafl
SIN3-HDAC complex associated factor, like
chr13_+_11828516 2.55 ENSDART00000110141
sufu
suppressor of fused homolog (Drosophila)
chr19_-_23249822 2.54 ENSDART00000140665
grb10a
growth factor receptor-bound protein 10a
chr2_+_15100742 2.53 ENSDART00000027171
f3b
coagulation factor IIIb
chr23_-_36305874 2.51 ENSDART00000147598
ENSDART00000146986
ENSDART00000086985
ENSDART00000133259
cbx5
chromobox homolog 5 (HP1 alpha homolog, Drosophila)
chr22_-_20814450 2.51 ENSDART00000089076
dot1l
DOT1-like histone H3K79 methyltransferase
chr11_-_12158412 2.51 ENSDART00000147670
npepps
aminopeptidase puromycin sensitive
chr22_+_5574952 2.51 ENSDART00000171774
zgc:171566
zgc:171566
chr8_-_26709959 2.50 ENSDART00000135215
tmem51a
transmembrane protein 51a
chr24_+_24086491 2.50 ENSDART00000145092
lipib
lipase, member Ib
chr2_+_25560556 2.50 ENSDART00000133623
pld1a
phospholipase D1a
chr21_-_2042037 2.49 ENSDART00000171131
ENSDART00000160144
add1
adducin 1 (alpha)
chr12_-_4249000 2.49 ENSDART00000059298
zgc:92313
zgc:92313
chr22_-_20924564 2.48 ENSDART00000100642
ENSDART00000032770
ell
elongation factor RNA polymerase II
chr23_-_36306337 2.48 ENSDART00000142760
ENSDART00000136929
ENSDART00000143340
cbx5
chromobox homolog 5 (HP1 alpha homolog, Drosophila)
chr7_+_34794829 2.48 ENSDART00000009698
ENSDART00000075089
ENSDART00000173456
esrp2
epithelial splicing regulatory protein 2
chr6_+_48206535 2.47 ENSDART00000075172
cttnbp2nla
CTTNBP2 N-terminal like a
chr16_-_22585289 2.47 ENSDART00000134239
ENSDART00000193959
ENSDART00000077998
si:dkey-238m4.3
cgna
si:dkey-238m4.3
cingulin a
chr5_+_4533244 2.47 ENSDART00000158826
CABZ01058650.1
Danio rerio thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 1 (LOC561325), mRNA.
chr15_-_31177324 2.47 ENSDART00000008854
wsb1
WD repeat and SOCS box containing 1
chr4_-_5795309 2.45 ENSDART00000039987
pgm3
phosphoglucomutase 3
chr9_+_22677503 2.45 ENSDART00000131429
ENSDART00000080005
ENSDART00000101756
ENSDART00000138148
itgb5
integrin, beta 5
chr14_-_31694274 2.44 ENSDART00000173353
map7d3
MAP7 domain containing 3
chr21_-_37027252 2.43 ENSDART00000076483
zgc:77151
zgc:77151
chr3_-_21118969 2.43 ENSDART00000129016
maza
MYC-associated zinc finger protein a (purine-binding transcription factor)

Network of associatons between targets according to the STRING database.

First level regulatory network of sp1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
5.3 15.8 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
2.7 11.0 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
2.2 6.6 GO:0034035 sulfate assimilation(GO:0000103) purine ribonucleoside bisphosphate metabolic process(GO:0034035) purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
1.9 5.7 GO:0090004 positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
1.9 5.6 GO:0060623 regulation of chromosome condensation(GO:0060623)
1.7 5.1 GO:0060571 invagination involved in gastrulation with mouth forming second(GO:0055109) morphogenesis of an epithelial fold(GO:0060571)
1.4 5.8 GO:0048308 organelle inheritance(GO:0048308) Golgi inheritance(GO:0048313)
1.4 4.2 GO:0045002 double-strand break repair via single-strand annealing(GO:0045002)
1.3 5.3 GO:0042306 regulation of protein import into nucleus(GO:0042306) negative regulation of protein import into nucleus(GO:0042308) negative regulation of nucleocytoplasmic transport(GO:0046823) negative regulation of protein localization to nucleus(GO:1900181) regulation of protein import(GO:1904589) negative regulation of protein import(GO:1904590)
1.3 3.8 GO:0035477 regulation of angioblast cell migration involved in selective angioblast sprouting(GO:0035477)
1.2 3.7 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
1.2 5.9 GO:0010586 miRNA metabolic process(GO:0010586)
1.1 3.4 GO:0045040 outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
1.1 8.8 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
1.1 3.3 GO:1901503 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) cellular lipid biosynthetic process(GO:0097384) ether biosynthetic process(GO:1901503)
1.1 5.3 GO:1900363 regulation of mRNA polyadenylation(GO:1900363)
1.0 4.0 GO:0055091 phospholipid homeostasis(GO:0055091)
1.0 3.9 GO:0034969 histone arginine methylation(GO:0034969)
1.0 3.8 GO:0021557 oculomotor nerve development(GO:0021557)
0.9 4.7 GO:0045056 transcytosis(GO:0045056)
0.9 6.5 GO:0040016 embryonic cleavage(GO:0040016)
0.9 3.4 GO:1904182 regulation of pyruvate dehydrogenase activity(GO:1904182) positive regulation of pyruvate dehydrogenase activity(GO:1904184)
0.8 3.4 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.8 4.2 GO:0010828 positive regulation of glucose transport(GO:0010828)
0.8 4.2 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
0.8 2.5 GO:0045601 regulation of endothelial cell differentiation(GO:0045601)
0.8 2.4 GO:0006601 creatine metabolic process(GO:0006600) creatine biosynthetic process(GO:0006601)
0.8 7.3 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.8 2.4 GO:0035676 anterior lateral line neuromast hair cell development(GO:0035676)
0.8 6.3 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.8 2.3 GO:1903792 negative regulation of anion transport(GO:1903792)
0.7 2.2 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.7 4.2 GO:0042795 snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.7 11.5 GO:0035803 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.7 4.0 GO:1900744 regulation of p38MAPK cascade(GO:1900744)
0.7 2.0 GO:0060063 Spemann organizer formation at the embryonic shield(GO:0060063)
0.6 4.5 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.6 1.9 GO:1904983 transmembrane glycine transport from cytosol to mitochondrion(GO:1904983)
0.6 1.9 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.6 5.8 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.6 6.4 GO:0031268 pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.6 5.1 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.6 2.5 GO:2000677 histone H3-K79 methylation(GO:0034729) regulation of transcription regulatory region DNA binding(GO:2000677)
0.6 2.5 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.6 2.5 GO:0032530 regulation of microvillus organization(GO:0032530) regulation of microvillus assembly(GO:0032534)
0.6 1.9 GO:1990869 response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869) negative regulation of lymphocyte migration(GO:2000402) negative regulation of T cell migration(GO:2000405)
0.6 2.4 GO:0010610 regulation of mRNA stability involved in response to stress(GO:0010610) regulation of mRNA stability involved in response to oxidative stress(GO:2000815)
0.6 4.8 GO:0040038 meiotic cytokinesis(GO:0033206) polar body extrusion after meiotic divisions(GO:0040038)
0.6 2.3 GO:0071869 response to monoamine(GO:0071867) response to catecholamine(GO:0071869) response to epinephrine(GO:0071871)
0.6 3.5 GO:0007603 phototransduction, visible light(GO:0007603)
0.6 1.7 GO:0005997 xylulose metabolic process(GO:0005997)
0.6 1.1 GO:0001692 histamine metabolic process(GO:0001692)
0.6 4.0 GO:0021534 cell proliferation in hindbrain(GO:0021534)
0.6 2.8 GO:0055071 manganese ion homeostasis(GO:0055071)
0.6 2.8 GO:0061439 renal system vasculature morphogenesis(GO:0061438) kidney vasculature morphogenesis(GO:0061439) glomerulus vasculature morphogenesis(GO:0072103) glomerular capillary formation(GO:0072104)
0.6 2.2 GO:0072314 glomerular visceral epithelial cell fate commitment(GO:0072149) glomerular epithelial cell fate commitment(GO:0072314)
0.5 4.4 GO:2000650 negative regulation of sodium ion transmembrane transporter activity(GO:2000650)
0.5 3.3 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.5 3.8 GO:0071233 response to leucine(GO:0043201) cellular response to leucine(GO:0071233) regulation of response to reactive oxygen species(GO:1901031)
0.5 1.6 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
0.5 3.2 GO:0060251 regulation of glial cell proliferation(GO:0060251)
0.5 3.1 GO:0003232 bulbus arteriosus development(GO:0003232)
0.5 3.1 GO:0060876 semicircular canal formation(GO:0060876)
0.5 1.5 GO:0061032 visceral serous pericardium development(GO:0061032)
0.5 1.4 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500) protein localization to ciliary membrane(GO:1903441)
0.5 5.0 GO:0090398 cellular senescence(GO:0090398)
0.4 1.3 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
0.4 3.1 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.4 6.6 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.4 1.8 GO:0003228 atrial cardiac muscle tissue development(GO:0003228)
0.4 3.4 GO:0070874 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.4 1.7 GO:1900120 regulation of cytokine activity(GO:0060300) regulation of receptor binding(GO:1900120) regulation of chemokine activity(GO:1900136)
0.4 1.7 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.4 0.8 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.4 2.0 GO:0017003 protein-heme linkage(GO:0017003) protein-tetrapyrrole linkage(GO:0017006) cytochrome c-heme linkage(GO:0018063)
0.4 1.9 GO:0034505 tooth mineralization(GO:0034505)
0.4 1.5 GO:1901166 neural crest cell migration involved in autonomic nervous system development(GO:1901166)
0.4 2.9 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.4 2.2 GO:0006083 acetate metabolic process(GO:0006083) acetyl-CoA biosynthetic process from acetate(GO:0019427)
0.4 4.3 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.4 3.9 GO:0006611 protein export from nucleus(GO:0006611)
0.4 1.8 GO:0018197 peptidyl-aspartic acid modification(GO:0018197) peptidyl-aspartic acid hydroxylation(GO:0042264)
0.4 0.7 GO:0032211 negative regulation of telomere maintenance via telomerase(GO:0032211) negative regulation of telomere maintenance via telomere lengthening(GO:1904357)
0.3 1.4 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.3 1.0 GO:0070417 cellular response to cold(GO:0070417)
0.3 2.9 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.3 5.5 GO:0019433 triglyceride catabolic process(GO:0019433)
0.3 1.3 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.3 1.6 GO:0080009 mRNA methylation(GO:0080009)
0.3 4.7 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.3 1.2 GO:0016332 establishment or maintenance of polarity of embryonic epithelium(GO:0016332)
0.3 1.5 GO:0060231 mesenchymal to epithelial transition(GO:0060231)
0.3 1.2 GO:0018343 protein farnesylation(GO:0018343)
0.3 2.4 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.3 1.8 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.3 1.7 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.3 6.0 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.3 1.4 GO:0003173 ventriculo bulbo valve development(GO:0003173)
0.3 0.8 GO:0019284 L-methionine biosynthetic process from S-adenosylmethionine(GO:0019284)
0.3 2.8 GO:0035090 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.3 5.8 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.3 2.7 GO:0030104 water homeostasis(GO:0030104)
0.3 1.6 GO:0060339 negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.3 3.0 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.3 1.3 GO:0090527 actin filament reorganization(GO:0090527)
0.3 2.1 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.3 0.8 GO:2000434 regulation of protein neddylation(GO:2000434)
0.3 2.0 GO:0046850 regulation of bone remodeling(GO:0046850)
0.2 2.2 GO:0055129 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.2 1.5 GO:0006013 mannose metabolic process(GO:0006013)
0.2 1.9 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.2 0.7 GO:0097113 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.2 0.5 GO:0090299 regulation of neural crest formation(GO:0090299)
0.2 1.7 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.2 3.5 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.2 1.6 GO:0051310 metaphase plate congression(GO:0051310)
0.2 2.0 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.2 2.5 GO:0042407 cristae formation(GO:0042407)
0.2 0.7 GO:0048682 axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
0.2 2.0 GO:0003160 endocardium morphogenesis(GO:0003160)
0.2 1.3 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.2 0.9 GO:0048011 neurotrophin TRK receptor signaling pathway(GO:0048011)
0.2 1.7 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.2 1.7 GO:0044528 regulation of mitochondrial mRNA stability(GO:0044528)
0.2 5.4 GO:0006884 cell volume homeostasis(GO:0006884)
0.2 1.3 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.2 6.7 GO:0036297 interstrand cross-link repair(GO:0036297)
0.2 0.8 GO:0006046 N-acetylglucosamine catabolic process(GO:0006046)
0.2 3.4 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.2 1.8 GO:0060036 notochord cell vacuolation(GO:0060036)
0.2 1.0 GO:0071322 cellular response to carbohydrate stimulus(GO:0071322) cellular response to monosaccharide stimulus(GO:0071326) cellular response to hexose stimulus(GO:0071331) cellular response to glucose stimulus(GO:0071333)
0.2 1.8 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) positive regulation of receptor activity(GO:2000273)
0.2 2.0 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.2 0.6 GO:1903523 negative regulation of heart contraction(GO:0045822) negative regulation of blood circulation(GO:1903523)
0.2 0.6 GO:0099552 trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
0.2 0.6 GO:0045724 positive regulation of cilium assembly(GO:0045724)
0.2 2.0 GO:0021681 cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702) cerebellar granule cell differentiation(GO:0021707)
0.2 1.3 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
0.2 3.3 GO:0046688 response to copper ion(GO:0046688)
0.2 0.7 GO:0048521 negative regulation of behavior(GO:0048521) negative regulation of feeding behavior(GO:2000252)
0.2 0.9 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.2 1.2 GO:0045050 protein insertion into ER membrane by stop-transfer membrane-anchor sequence(GO:0045050)
0.2 0.9 GO:0048885 neuromast deposition(GO:0048885)
0.2 0.7 GO:0046958 nonassociative learning(GO:0046958) habituation(GO:0046959)
0.2 1.8 GO:0050714 positive regulation of protein secretion(GO:0050714)
0.2 1.1 GO:0048745 smooth muscle tissue development(GO:0048745)
0.2 2.4 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.2 2.1 GO:0031937 methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.2 0.8 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.2 1.3 GO:0002082 regulation of oxidative phosphorylation(GO:0002082)
0.2 0.5 GO:1900180 regulation of protein localization to nucleus(GO:1900180)
0.2 1.7 GO:0006382 adenosine to inosine editing(GO:0006382)
0.2 2.0 GO:0099638 neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887) endosome to plasma membrane protein transport(GO:0099638) neurotransmitter receptor transport, endosome to plasma membrane(GO:0099639)
0.2 2.6 GO:0008089 anterograde axonal transport(GO:0008089)
0.1 0.7 GO:0000012 single strand break repair(GO:0000012)
0.1 1.6 GO:0006735 glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.1 1.7 GO:0048922 posterior lateral line neuromast deposition(GO:0048922)
0.1 4.8 GO:0045332 phospholipid translocation(GO:0045332)
0.1 1.5 GO:0098719 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 1.8 GO:0002084 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.1 0.7 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.1 0.6 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065)
0.1 6.0 GO:0070830 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.1 0.8 GO:0070650 actin filament bundle distribution(GO:0070650)
0.1 0.7 GO:1905097 regulation of guanyl-nucleotide exchange factor activity(GO:1905097) regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.1 0.5 GO:0006526 arginine biosynthetic process(GO:0006526)
0.1 0.8 GO:0015959 diadenosine polyphosphate metabolic process(GO:0015959) diadenosine polyphosphate catabolic process(GO:0015961)
0.1 2.3 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.1 2.1 GO:0030316 osteoclast differentiation(GO:0030316)
0.1 8.2 GO:0051693 actin filament capping(GO:0051693)
0.1 1.5 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026) negative regulation of microtubule polymerization or depolymerization(GO:0031111)
0.1 4.7 GO:0072114 pronephros morphogenesis(GO:0072114)
0.1 3.9 GO:0014866 skeletal myofibril assembly(GO:0014866)
0.1 1.0 GO:0006478 protein sulfation(GO:0006477) peptidyl-tyrosine sulfation(GO:0006478)
0.1 1.7 GO:0009303 rRNA transcription(GO:0009303)
0.1 0.6 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.1 1.3 GO:0046146 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.1 1.4 GO:0006622 protein targeting to lysosome(GO:0006622)
0.1 0.6 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.1 0.7 GO:0010269 response to selenium ion(GO:0010269)
0.1 2.8 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.1 1.2 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.1 9.0 GO:0048916 posterior lateral line development(GO:0048916)
0.1 0.8 GO:0032366 intracellular sterol transport(GO:0032366)
0.1 0.9 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.1 1.6 GO:0061055 myotome development(GO:0061055)
0.1 0.7 GO:0003272 endocardial cushion formation(GO:0003272)
0.1 5.3 GO:0051453 regulation of intracellular pH(GO:0051453)
0.1 1.8 GO:2000117 negative regulation of cysteine-type endopeptidase activity(GO:2000117)
0.1 1.9 GO:0098962 regulation of postsynaptic neurotransmitter receptor activity(GO:0098962)
0.1 1.3 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.1 1.4 GO:0008053 mitochondrial fusion(GO:0008053)
0.1 1.1 GO:0032231 regulation of actin filament bundle assembly(GO:0032231) positive regulation of actin filament bundle assembly(GO:0032233)
0.1 0.3 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 2.5 GO:0048814 regulation of dendrite morphogenesis(GO:0048814)
0.1 1.1 GO:0010765 positive regulation of sodium ion transport(GO:0010765) positive regulation of sodium ion transmembrane transport(GO:1902307) regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288) positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.1 6.1 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.1 0.9 GO:0048207 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.1 1.3 GO:0044275 cellular carbohydrate catabolic process(GO:0044275)
0.1 3.7 GO:0008299 isoprenoid biosynthetic process(GO:0008299)
0.1 1.5 GO:0019985 translesion synthesis(GO:0019985)
0.1 2.6 GO:0090148 membrane fission(GO:0090148)
0.1 9.6 GO:0031098 stress-activated protein kinase signaling cascade(GO:0031098)
0.1 0.2 GO:0042560 10-formyltetrahydrofolate metabolic process(GO:0009256) 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
0.1 0.8 GO:0071684 hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.1 1.4 GO:0006767 water-soluble vitamin metabolic process(GO:0006767)
0.1 0.9 GO:0043931 ossification involved in bone maturation(GO:0043931) bone maturation(GO:0070977)
0.1 0.7 GO:1905066 regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066)
0.1 8.0 GO:0061640 cytoskeleton-dependent cytokinesis(GO:0061640)
0.1 0.5 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.1 0.9 GO:2000036 regulation of stem cell population maintenance(GO:2000036)
0.1 2.3 GO:0045879 negative regulation of smoothened signaling pathway(GO:0045879)
0.1 5.5 GO:0051402 neuron apoptotic process(GO:0051402)
0.1 0.4 GO:0051561 positive regulation of mitochondrial calcium ion concentration(GO:0051561)
0.1 1.0 GO:0003139 secondary heart field specification(GO:0003139)
0.1 0.5 GO:0032218 riboflavin transport(GO:0032218)
0.1 6.5 GO:0051028 mRNA transport(GO:0051028)
0.1 1.5 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.1 2.7 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.1 5.3 GO:0006073 glycogen metabolic process(GO:0005977) cellular glucan metabolic process(GO:0006073) glucan metabolic process(GO:0044042)
0.1 2.6 GO:0030336 negative regulation of cell migration(GO:0030336)
0.1 0.8 GO:0021754 facial nucleus development(GO:0021754)
0.1 2.0 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.1 0.2 GO:0098773 skin epidermis development(GO:0098773)
0.1 1.4 GO:0022011 myelination in peripheral nervous system(GO:0022011)
0.1 0.2 GO:0035767 endothelial cell chemotaxis(GO:0035767)
0.1 2.3 GO:0048538 thymus development(GO:0048538)
0.1 2.1 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.1 2.1 GO:0015012 heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.1 0.2 GO:0001112 DNA-templated transcriptional open complex formation(GO:0001112) transcriptional open complex formation at RNA polymerase II promoter(GO:0001113) protein-DNA complex remodeling(GO:0001120)
0.1 0.3 GO:0072506 phosphate ion homeostasis(GO:0055062) trivalent inorganic anion homeostasis(GO:0072506)
0.1 6.2 GO:0031101 fin regeneration(GO:0031101)
0.1 13.5 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.1 4.5 GO:0042552 myelination(GO:0042552)
0.1 1.6 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.1 1.2 GO:0030259 lipid glycosylation(GO:0030259)
0.1 1.5 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.1 0.5 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.1 6.1 GO:0030178 negative regulation of Wnt signaling pathway(GO:0030178)
0.1 1.6 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.1 1.2 GO:0010737 protein kinase A signaling(GO:0010737)
0.1 0.9 GO:1902254 negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902254)
0.1 0.9 GO:0090114 COPII-coated vesicle budding(GO:0090114)
0.1 0.3 GO:0007624 ultradian rhythm(GO:0007624)
0.1 1.5 GO:0051092 positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.1 0.9 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.1 4.4 GO:0006911 phagocytosis, engulfment(GO:0006911)
0.1 0.2 GO:1990519 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.1 1.3 GO:0055078 sodium ion homeostasis(GO:0055078)
0.1 1.6 GO:0034968 histone lysine methylation(GO:0034968)
0.1 4.0 GO:0044344 fibroblast growth factor receptor signaling pathway(GO:0008543) cellular response to fibroblast growth factor stimulus(GO:0044344) response to fibroblast growth factor(GO:0071774)
0.1 1.0 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.1 0.5 GO:0035372 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.1 0.3 GO:0071380 response to prostaglandin E(GO:0034695) cellular response to prostaglandin E stimulus(GO:0071380)
0.1 0.2 GO:0014909 smooth muscle cell migration(GO:0014909)
0.1 0.5 GO:0000186 activation of MAPKK activity(GO:0000186)
0.1 0.7 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.1 1.6 GO:0030223 neutrophil differentiation(GO:0030223)
0.1 2.3 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1 1.1 GO:0040023 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.0 0.6 GO:0032094 response to food(GO:0032094)
0.0 0.2 GO:0003245 growth involved in heart morphogenesis(GO:0003241) cardiac chamber ballooning(GO:0003242) cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.0 1.3 GO:0046847 filopodium assembly(GO:0046847)
0.0 2.0 GO:0001841 neural tube formation(GO:0001841)
0.0 0.4 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 5.4 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.1 GO:0045921 positive regulation of exocytosis(GO:0045921)
0.0 1.3 GO:0043149 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.0 4.7 GO:0006821 chloride transport(GO:0006821)
0.0 0.6 GO:0099518 vesicle cytoskeletal trafficking(GO:0099518)
0.0 2.1 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 6.5 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 0.4 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 1.2 GO:0043171 peptide catabolic process(GO:0043171)
0.0 1.1 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 2.9 GO:0048846 axon extension involved in axon guidance(GO:0048846) neuron projection extension involved in neuron projection guidance(GO:1902284)
0.0 2.1 GO:0007052 mitotic spindle organization(GO:0007052)
0.0 1.1 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.0 0.5 GO:0010996 response to auditory stimulus(GO:0010996)
0.0 4.4 GO:0016236 macroautophagy(GO:0016236)
0.0 0.2 GO:0048014 Tie signaling pathway(GO:0048014)
0.0 0.8 GO:0006828 manganese ion transport(GO:0006828)
0.0 1.1 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.8 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 0.2 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.0 0.6 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 1.9 GO:0006338 chromatin remodeling(GO:0006338)
0.0 0.4 GO:0015693 magnesium ion transport(GO:0015693)
0.0 2.5 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 0.2 GO:1902742 apoptotic process involved in morphogenesis(GO:0060561) apoptotic process involved in development(GO:1902742)
0.0 0.3 GO:0006024 glycosaminoglycan biosynthetic process(GO:0006024)
0.0 0.0 GO:0007612 learning(GO:0007612)
0.0 1.9 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.0 0.7 GO:0099645 protein localization to postsynaptic specialization membrane(GO:0099633) neurotransmitter receptor localization to postsynaptic specialization membrane(GO:0099645)
0.0 0.4 GO:0046686 response to cadmium ion(GO:0046686)
0.0 0.4 GO:0097192 signal transduction in absence of ligand(GO:0038034) extrinsic apoptotic signaling pathway in absence of ligand(GO:0097192)
0.0 0.2 GO:0009247 glycolipid biosynthetic process(GO:0009247)
0.0 0.9 GO:0016575 histone deacetylation(GO:0016575)
0.0 0.5 GO:0001757 somite specification(GO:0001757) segment specification(GO:0007379)
0.0 2.6 GO:0008654 phospholipid biosynthetic process(GO:0008654)
0.0 0.4 GO:0007041 lysosomal transport(GO:0007041)
0.0 5.7 GO:0043413 protein glycosylation(GO:0006486) macromolecule glycosylation(GO:0043413)
0.0 0.8 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 0.3 GO:1903321 negative regulation of protein ubiquitination(GO:0031397) negative regulation of protein modification by small protein conjugation or removal(GO:1903321)
0.0 0.1 GO:1901162 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.0 2.3 GO:0045055 regulated exocytosis(GO:0045055)
0.0 0.1 GO:0055107 Golgi to secretory granule transport(GO:0055107)
0.0 0.6 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 1.2 GO:0030048 actin filament-based movement(GO:0030048)
0.0 0.2 GO:0001516 prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
0.0 0.1 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.7 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 0.6 GO:0006909 phagocytosis(GO:0006909)
0.0 1.7 GO:0006887 exocytosis(GO:0006887)
0.0 0.5 GO:1902593 protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744) single-organism nuclear import(GO:1902593)
0.0 0.1 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.1 GO:0002154 thyroid hormone mediated signaling pathway(GO:0002154)
0.0 2.7 GO:0006644 phospholipid metabolic process(GO:0006644)
0.0 2.1 GO:0006399 tRNA metabolic process(GO:0006399)
0.0 0.2 GO:0035778 pronephric nephron tubule epithelial cell differentiation(GO:0035778) cell differentiation involved in pronephros development(GO:0039014) nephron tubule epithelial cell differentiation(GO:0072160)
0.0 0.3 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 0.1 GO:0061026 cardiac muscle tissue regeneration(GO:0061026)
0.0 0.3 GO:1904892 regulation of JAK-STAT cascade(GO:0046425) regulation of STAT cascade(GO:1904892)
0.0 0.3 GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity(GO:0051091)
0.0 0.1 GO:0043981 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 0.2 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.5 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.7 GO:0042493 response to drug(GO:0042493)
0.0 0.1 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.0 0.2 GO:0035305 negative regulation of dephosphorylation(GO:0035305) negative regulation of protein dephosphorylation(GO:0035308)
0.0 0.2 GO:0032355 response to estradiol(GO:0032355)
0.0 1.0 GO:0016197 endosomal transport(GO:0016197)
0.0 0.2 GO:0034472 snRNA 3'-end processing(GO:0034472)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 7.3 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
1.3 5.3 GO:0035301 Hedgehog signaling complex(GO:0035301)
0.8 2.4 GO:0098536 deuterosome(GO:0098536)
0.7 3.3 GO:0008091 spectrin(GO:0008091)
0.7 2.6 GO:0043291 RAVE complex(GO:0043291)
0.6 5.0 GO:0035060 brahma complex(GO:0035060)
0.5 8.2 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.5 10.1 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.5 3.8 GO:0061700 GATOR2 complex(GO:0061700)
0.4 4.7 GO:0045095 keratin filament(GO:0045095)
0.4 3.4 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
0.4 1.6 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.4 2.7 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.4 5.2 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.3 2.4 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.3 1.4 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.3 1.0 GO:0070578 RISC-loading complex(GO:0070578)
0.3 2.3 GO:0048500 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.3 1.3 GO:0060171 stereocilium membrane(GO:0060171)
0.3 2.2 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.3 1.2 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.3 2.9 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.3 2.3 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.3 1.4 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.3 0.8 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.3 1.0 GO:1902737 dendritic spine neck(GO:0044326) dendritic filopodium(GO:1902737)
0.2 1.5 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006) catalytic step 1 spliceosome(GO:0071012)
0.2 0.7 GO:1990879 CST complex(GO:1990879)
0.2 0.9 GO:0032584 growth cone membrane(GO:0032584)
0.2 2.6 GO:0016580 Sin3 complex(GO:0016580)
0.2 1.9 GO:0031526 brush border membrane(GO:0031526)
0.2 15.5 GO:0031902 late endosome membrane(GO:0031902)
0.2 2.2 GO:0035101 FACT complex(GO:0035101)
0.2 1.4 GO:0016234 inclusion body(GO:0016234)
0.2 1.5 GO:0000813 ESCRT I complex(GO:0000813)
0.2 1.3 GO:0001650 fibrillar center(GO:0001650)
0.2 1.9 GO:0000812 Swr1 complex(GO:0000812)
0.2 23.7 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.2 3.7 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.2 0.6 GO:0005592 collagen type XI trimer(GO:0005592)
0.2 1.3 GO:0043194 axon initial segment(GO:0043194)
0.2 3.6 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.2 0.8 GO:0042584 chromaffin granule membrane(GO:0042584)
0.2 6.1 GO:0032156 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.2 1.8 GO:0030904 retromer complex(GO:0030904)
0.2 2.4 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.2 0.6 GO:0071556 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.2 0.6 GO:0098890 extrinsic component of postsynaptic membrane(GO:0098890)
0.2 2.1 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.2 1.1 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.1 1.5 GO:0036449 microtubule minus-end(GO:0036449)
0.1 1.6 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.1 6.5 GO:0030175 filopodium(GO:0030175)
0.1 1.4 GO:0060170 ciliary membrane(GO:0060170)
0.1 1.1 GO:0016272 prefoldin complex(GO:0016272)
0.1 1.4 GO:0071782 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.1 7.3 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 1.2 GO:0072546 ER membrane protein complex(GO:0072546)
0.1 10.4 GO:0055037 recycling endosome(GO:0055037)
0.1 1.0 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 0.3 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.1 0.4 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.1 1.0 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 8.2 GO:0000922 spindle pole(GO:0000922)
0.1 0.5 GO:0005903 brush border(GO:0005903)
0.1 3.4 GO:0032432 actin filament bundle(GO:0032432)
0.1 1.8 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 1.3 GO:0015030 Cajal body(GO:0015030)
0.1 1.9 GO:0045180 basal cortex(GO:0045180)
0.1 4.2 GO:0008023 transcription elongation factor complex(GO:0008023)
0.1 1.6 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.1 4.5 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 3.5 GO:0001750 photoreceptor outer segment(GO:0001750)
0.1 1.4 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.1 3.1 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1 0.7 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1 8.0 GO:0016459 myosin complex(GO:0016459)
0.1 1.1 GO:0030008 TRAPP complex(GO:0030008)
0.1 0.6 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.1 0.5 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.1 1.1 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 2.8 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.1 2.5 GO:0000779 condensed chromosome, centromeric region(GO:0000779)
0.1 5.3 GO:0005802 trans-Golgi network(GO:0005802)
0.1 2.4 GO:0098636 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.1 0.9 GO:0030667 secretory granule membrane(GO:0030667)
0.0 0.5 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 2.5 GO:0005773 vacuole(GO:0005773)
0.0 1.4 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.8 GO:0030057 desmosome(GO:0030057)
0.0 0.2 GO:0005673 transcription factor TFIIE complex(GO:0005673)
0.0 2.9 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.9 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.9 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.0 5.2 GO:0030659 cytoplasmic vesicle membrane(GO:0030659)
0.0 3.3 GO:0005871 kinesin complex(GO:0005871)
0.0 0.9 GO:0001518 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 0.5 GO:0051233 spindle midzone(GO:0051233)
0.0 1.2 GO:0030139 endocytic vesicle(GO:0030139)
0.0 0.8 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 2.9 GO:0048475 membrane coat(GO:0030117) coated membrane(GO:0048475)
0.0 1.0 GO:0032587 ruffle membrane(GO:0032587)
0.0 1.2 GO:0072686 mitotic spindle(GO:0072686)
0.0 0.8 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 9.3 GO:0005730 nucleolus(GO:0005730)
0.0 2.4 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 2.4 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 0.6 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 1.3 GO:0005811 lipid particle(GO:0005811)
0.0 2.7 GO:0005884 actin filament(GO:0005884)
0.0 0.3 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 1.9 GO:0016324 apical plasma membrane(GO:0016324)
0.0 1.1 GO:0016592 mediator complex(GO:0016592)
0.0 20.5 GO:0005783 endoplasmic reticulum(GO:0005783)
0.0 0.1 GO:0070319 Golgi to plasma membrane transport vesicle(GO:0070319)
0.0 2.4 GO:0005764 lysosome(GO:0005764)
0.0 0.1 GO:0034359 mature chylomicron(GO:0034359)
0.0 0.7 GO:0098978 glutamatergic synapse(GO:0098978)
0.0 9.5 GO:0005654 nucleoplasm(GO:0005654)
0.0 13.7 GO:0012505 endomembrane system(GO:0012505)
0.0 0.1 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.1 GO:0016602 CCAAT-binding factor complex(GO:0016602)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 6.6 GO:0004020 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
1.8 5.5 GO:0045145 single-stranded DNA 5'-3' exodeoxyribonuclease activity(GO:0045145)
1.4 5.7 GO:0071253 connexin binding(GO:0071253)
1.4 4.2 GO:0008386 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
1.3 3.9 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
1.1 7.4 GO:0008118 N-acetyllactosaminide alpha-2,3-sialyltransferase activity(GO:0008118)
1.0 11.5 GO:0035804 structural constituent of egg coat(GO:0035804)
1.0 13.7 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.9 3.4 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.8 2.5 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.7 2.1 GO:0008517 folic acid transporter activity(GO:0008517)
0.7 2.7 GO:0001096 TFIIF-class transcription factor binding(GO:0001096)
0.7 10.0 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.6 3.1 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184) 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.6 2.5 GO:0031151 histone methyltransferase activity (H3-K79 specific)(GO:0031151)
0.6 5.6 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.6 5.9 GO:0035198 miRNA binding(GO:0035198)
0.6 2.3 GO:0016842 amidine-lyase activity(GO:0016842)
0.6 1.7 GO:0031701 angiotensin receptor binding(GO:0031701)
0.6 1.7 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.5 4.4 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.5 3.8 GO:0070728 leucine binding(GO:0070728)
0.5 2.1 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.5 5.3 GO:0035925 AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.5 2.0 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.5 1.0 GO:0070883 pre-miRNA binding(GO:0070883)
0.5 5.5 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.5 2.8 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.5 1.9 GO:0071889 14-3-3 protein binding(GO:0071889)
0.4 2.2 GO:0050218 propionate-CoA ligase activity(GO:0050218)
0.4 2.2 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.4 5.3 GO:0005158 insulin receptor binding(GO:0005158)
0.4 1.8 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.4 1.3 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.4 2.0 GO:0004408 holocytochrome-c synthase activity(GO:0004408)
0.4 7.4 GO:0008301 DNA binding, bending(GO:0008301)
0.4 1.9 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.4 3.7 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.4 1.1 GO:0004736 pyruvate carboxylase activity(GO:0004736)
0.4 3.3 GO:0004096 catalase activity(GO:0004096)
0.4 2.9 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.4 3.9 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.4 2.5 GO:0004630 phospholipase D activity(GO:0004630)
0.4 1.8 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.3 3.0 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.3 1.3 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.3 1.3 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.3 1.5 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.3 2.7 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.3 1.2 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.3 9.2 GO:0042287 MHC protein binding(GO:0042287)
0.3 2.4 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.3 0.9 GO:0043621 protein self-association(GO:0043621)
0.3 1.1 GO:0004373 glycogen (starch) synthase activity(GO:0004373)
0.3 5.8 GO:0036002 pre-mRNA binding(GO:0036002)
0.3 8.2 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.3 0.5 GO:0008312 7S RNA binding(GO:0008312)
0.3 1.3 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.3 1.3 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.2 5.7 GO:0015299 solute:proton antiporter activity(GO:0015299)
0.2 0.7 GO:0051500 D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500)
0.2 1.9 GO:0072518 Rho-dependent protein serine/threonine kinase activity(GO:0072518)
0.2 0.7 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.2 1.9 GO:0016530 metallochaperone activity(GO:0016530)
0.2 3.0 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.2 1.8 GO:0031419 cobalamin binding(GO:0031419)
0.2 2.5 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.2 10.9 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.2 0.7 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.2 1.3 GO:0017070 U6 snRNA binding(GO:0017070)
0.2 5.4 GO:0015377 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.2 0.8 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.2 1.3 GO:0015616 DNA translocase activity(GO:0015616)
0.2 1.4 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.2 2.0 GO:0050700 CARD domain binding(GO:0050700)
0.2 2.5 GO:0005537 mannose binding(GO:0005537)
0.2 1.1 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.2 3.7 GO:0070411 I-SMAD binding(GO:0070411)
0.2 3.1 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.2 7.0 GO:0015459 potassium channel regulator activity(GO:0015459)
0.2 0.7 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.2 2.3 GO:0034595 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439) phosphatidylinositol phosphate 5-phosphatase activity(GO:0034595)
0.2 0.8 GO:0033842 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity(GO:0033842)
0.2 1.3 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.2 1.5 GO:0030507 spectrin binding(GO:0030507)
0.2 4.3 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.2 0.6 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.2 8.0 GO:0031491 nucleosome binding(GO:0031491)
0.2 1.7 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.2 2.2 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.2 0.6 GO:0046997 oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.1 1.0 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.1 1.8 GO:0043495 protein anchor(GO:0043495)
0.1 4.0 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 3.1 GO:0004659 prenyltransferase activity(GO:0004659)
0.1 4.3 GO:0030165 PDZ domain binding(GO:0030165)
0.1 2.1 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.1 1.6 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.1 4.5 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 1.0 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.1 3.4 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 0.9 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.1 1.6 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.1 1.0 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.1 1.6 GO:0061665 SUMO ligase activity(GO:0061665)
0.1 1.1 GO:0070840 dynein complex binding(GO:0070840)
0.1 0.4 GO:0008022 protein C-terminus binding(GO:0008022)
0.1 0.6 GO:0070644 vitamin D response element binding(GO:0070644)
0.1 5.2 GO:0008013 beta-catenin binding(GO:0008013)
0.1 2.2 GO:0002039 p53 binding(GO:0002039)
0.1 1.5 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.1 1.1 GO:0043515 kinetochore binding(GO:0043515)
0.1 2.8 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 0.8 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 0.3 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.1 0.5 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307)
0.1 2.1 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.1 0.4 GO:0033204 ribonuclease P RNA binding(GO:0033204)
0.1 3.6 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 0.5 GO:0001735 prenylcysteine oxidase activity(GO:0001735)
0.1 1.9 GO:0008242 omega peptidase activity(GO:0008242)
0.1 2.7 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.1 1.3 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 0.8 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.1 1.4 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.1 8.2 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.1 1.3 GO:0016783 sulfurtransferase activity(GO:0016783)
0.1 4.6 GO:0005548 phospholipid transporter activity(GO:0005548)
0.1 1.4 GO:0051879 Hsp90 protein binding(GO:0051879)
0.1 0.5 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.1 1.2 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 0.6 GO:0035173 histone kinase activity(GO:0035173)
0.1 1.8 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 0.5 GO:0032217 riboflavin transporter activity(GO:0032217)
0.1 1.1 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.1 0.6 GO:0099530 G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530)
0.1 1.4 GO:0016273 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.1 1.6 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.1 2.9 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.1 3.5 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 3.0 GO:0003725 double-stranded RNA binding(GO:0003725)
0.1 0.8 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 1.8 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 10.9 GO:0003714 transcription corepressor activity(GO:0003714)
0.1 2.4 GO:0016769 transferase activity, transferring nitrogenous groups(GO:0016769)
0.1 1.1 GO:2001069 glycogen binding(GO:2001069)
0.1 1.4 GO:0051087 chaperone binding(GO:0051087)
0.1 0.9 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1 1.6 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1 2.3 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.1 0.2 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.1 3.4 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.1 0.6 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 1.4 GO:0097602 cullin family protein binding(GO:0097602)
0.1 0.5 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.1 0.8 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.1 1.5 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 4.2 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 2.4 GO:0019003 GDP binding(GO:0019003)
0.1 0.4 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.1 0.4 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 0.7 GO:0004046 aminoacylase activity(GO:0004046)
0.1 0.2 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.1 1.4 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.1 5.3 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.1 0.4 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.1 13.8 GO:0003774 motor activity(GO:0003774)
0.1 2.1 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.1 0.8 GO:0005080 protein kinase C binding(GO:0005080)
0.1 0.8 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 1.4 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 7.7 GO:0060090 binding, bridging(GO:0060090)
0.0 1.1 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.3 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 1.3 GO:0015248 sterol transporter activity(GO:0015248)
0.0 1.0 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 9.8 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 0.9 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.7 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.4 GO:0015168 glycerol transmembrane transporter activity(GO:0015168)
0.0 11.1 GO:0003712 transcription factor activity, transcription factor binding(GO:0000989) transcription cofactor activity(GO:0003712)
0.0 7.8 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.4 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.8 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.4 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 1.2 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.4 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.1 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 11.3 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.4 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 1.0 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 2.1 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 2.1 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.6 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 11.1 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.1 GO:1990699 palmitoleyl hydrolase activity(GO:1990699)
0.0 0.3 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.7 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 2.2 GO:0030276 clathrin binding(GO:0030276)
0.0 0.6 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.3 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 1.9 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 5.0 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.0 0.4 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.2 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.1 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.0 0.8 GO:0019213 deacetylase activity(GO:0019213)
0.0 0.3 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.5 GO:0017069 snRNA binding(GO:0017069)
0.0 0.3 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.3 GO:0050811 GABA receptor binding(GO:0050811)
0.0 1.1 GO:0071949 FAD binding(GO:0071949)
0.0 4.5 GO:0005543 phospholipid binding(GO:0005543)
0.0 0.2 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.5 GO:0016878 acid-thiol ligase activity(GO:0016878)
0.0 3.3 GO:0042393 histone binding(GO:0042393)
0.0 0.7 GO:0003684 damaged DNA binding(GO:0003684)
0.0 0.3 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.3 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.0 18.2 GO:0008270 zinc ion binding(GO:0008270)
0.0 0.6 GO:0000049 tRNA binding(GO:0000049)
0.0 1.1 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.1 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.1 GO:0016405 CoA-ligase activity(GO:0016405)
0.0 4.0 GO:0051015 actin filament binding(GO:0051015)
0.0 0.2 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.3 GO:0045134 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.0 0.1 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.1 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.0 0.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 1.2 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.1 GO:0005042 netrin receptor activity(GO:0005042)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.3 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.4 8.8 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.4 17.1 PID FOXO PATHWAY FoxO family signaling
0.3 3.1 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.3 2.2 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.3 9.9 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.3 3.8 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.3 3.0 PID EPHB FWD PATHWAY EPHB forward signaling
0.3 9.0 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.3 1.8 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.2 2.7 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.2 4.9 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.2 8.3 PID AURORA B PATHWAY Aurora B signaling
0.2 5.4 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.2 4.3 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.2 3.9 PID NCADHERIN PATHWAY N-cadherin signaling events
0.2 3.8 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.2 3.7 PID ARF6 PATHWAY Arf6 signaling events
0.2 3.3 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.2 1.7 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.2 1.4 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.2 10.3 PID P73PATHWAY p73 transcription factor network
0.2 2.7 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.2 3.3 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.2 0.5 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 10.2 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.1 0.5 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.1 1.3 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 2.0 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 1.3 PID NETRIN PATHWAY Netrin-mediated signaling events
0.1 0.5 PID IL3 PATHWAY IL3-mediated signaling events
0.1 1.1 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 1.0 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 4.3 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.1 1.5 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.1 2.9 PID AR PATHWAY Coregulation of Androgen receptor activity
0.1 0.6 PID ATF2 PATHWAY ATF-2 transcription factor network
0.1 1.0 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.1 0.7 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.1 1.1 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 1.4 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.9 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 1.3 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.9 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.9 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.7 PID BMP PATHWAY BMP receptor signaling
0.0 4.6 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 2.0 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 1.1 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 0.3 PID ATM PATHWAY ATM pathway
0.0 0.2 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.5 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.3 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.5 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.0 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.3 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.2 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 0.4 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.1 ST GA13 PATHWAY G alpha 13 Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 10.7 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
1.0 3.8 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.7 7.3 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.7 3.3 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.6 5.6 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.4 3.1 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.4 2.2 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.4 4.7 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.4 9.8 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.3 1.7 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.3 6.9 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.3 2.8 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.3 2.4 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.3 0.3 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.3 4.3 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.2 3.4 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.2 3.5 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.2 3.3 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.2 2.1 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.2 4.1 REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.2 0.8 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.2 9.4 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.2 1.3 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.2 3.3 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.2 3.7 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.2 1.9 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.2 1.9 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.2 1.7 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.2 3.7 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 3.1 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.1 1.8 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 1.0 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.1 0.7 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 2.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 1.1 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.1 0.3 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 1.3 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 0.5 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.1 1.5 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.1 9.1 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.1 1.4 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.1 2.2 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 1.4 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 19.0 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.1 2.1 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.1 1.5 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 2.0 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.1 1.7 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1 2.2 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.1 1.5 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.1 2.5 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.1 0.6 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.1 2.9 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.1 6.0 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.1 6.0 REACTOME DIABETES PATHWAYS Genes involved in Diabetes pathways
0.0 2.1 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.1 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 1.5 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.5 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0 1.1 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 0.2 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.9 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.5 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.2 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0 0.7 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.4 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.2 REACTOME IL 2 SIGNALING Genes involved in Interleukin-2 signaling
0.0 0.4 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 1.9 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.5 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
0.0 0.1 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 1.6 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.1 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex