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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for sp3b

Z-value: 0.83

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Transcription factors associated with sp3b

Gene Symbol Gene ID Gene Info
sp3b
ENSDARG00000007812 Sp3b transcription factor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
sp3bdr11_v1_chr6_-_10728057_10728057-0.898.2e-07Click!

Activity profile of sp3b motif

Sorted Z-values of sp3b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr10_-_44924289 4.57 ENSDART00000171267
tuba7l
tubulin, alpha 7 like
chr10_-_641609 4.13 ENSDART00000041236
rfx3
regulatory factor X, 3 (influences HLA class II expression)
chr6_-_60104628 4.03 ENSDART00000057463
ENSDART00000169188
pmepa1
prostate transmembrane protein, androgen induced 1
chr20_-_147574 3.35 ENSDART00000104762
ENSDART00000131635
slc16a10
solute carrier family 16 (aromatic amino acid transporter), member 10
chr2_-_44183451 3.32 ENSDART00000111246
cadm3
cell adhesion molecule 3
chr7_-_16598212 3.10 ENSDART00000128488
e2f8
E2F transcription factor 8
chr2_-_44183613 2.85 ENSDART00000079596
cadm3
cell adhesion molecule 3
chr6_+_475264 2.68 ENSDART00000193615
LO017974.1

chr3_-_16227683 2.61 ENSDART00000111707
cacnb1
calcium channel, voltage-dependent, beta 1 subunit
chr15_+_19838458 2.27 ENSDART00000101204
alcamb
activated leukocyte cell adhesion molecule b
chr16_-_45058919 2.15 ENSDART00000177134
gapdhs
glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
chr6_+_7249531 2.05 ENSDART00000125912
ENSDART00000083424
ENSDART00000049695
ENSDART00000136088
dzip1
DAZ interacting zinc finger protein 1
chr24_+_33622769 2.03 ENSDART00000079342
dnah5l
dynein, axonemal, heavy chain 5 like
chr19_-_31802296 2.01 ENSDART00000103640
hey1
hes-related family bHLH transcription factor with YRPW motif 1
chr14_-_2933185 1.98 ENSDART00000161677
ENSDART00000162446
ENSDART00000109378
si:dkey-201i24.6
si:dkey-201i24.6
chr3_+_1211242 1.93 ENSDART00000171287
ENSDART00000165769
poldip3
polymerase (DNA-directed), delta interacting protein 3
chr6_+_29217392 1.91 ENSDART00000006386
atp1b1a
ATPase Na+/K+ transporting subunit beta 1a
chr7_-_10560964 1.88 ENSDART00000172761
ENSDART00000170476
mthfs
5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
chr5_-_68022631 1.86 ENSDART00000143199
wasf3a
WAS protein family, member 3a
chr7_+_34688527 1.86 ENSDART00000108473
plekhg4
pleckstrin homology domain containing, family G (with RhoGef domain) member 4
chr19_+_935565 1.81 ENSDART00000113368
RNF5
ring finger protein 5
chr19_+_48111285 1.77 ENSDART00000169420
nme2b.2
NME/NM23 nucleoside diphosphate kinase 2b, tandem duplicate 2
chr25_+_1732838 1.76 ENSDART00000159555
ENSDART00000168161
FBLN1
fibulin 1
chr8_+_27555314 1.75 ENSDART00000135568
ENSDART00000016696
rhocb
ras homolog family member Cb
chr20_-_7080427 1.73 ENSDART00000140166
ENSDART00000023677
si:ch211-121a2.2
si:ch211-121a2.2
chr21_-_43015383 1.73 ENSDART00000065097
dpysl3
dihydropyrimidinase-like 3
chr1_-_59232267 1.72 ENSDART00000169658
ENSDART00000163257
akap8l
A kinase (PRKA) anchor protein 8-like
chr23_+_17220986 1.71 ENSDART00000054761
nol4lb
nucleolar protein 4-like b
chr19_+_636886 1.67 ENSDART00000149192
tert
telomerase reverse transcriptase
chr20_-_53981626 1.66 ENSDART00000023550
hsp90aa1.2
heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2
chr10_-_39154778 1.64 ENSDART00000186811
slc37a4b
solute carrier family 37 (glucose-6-phosphate transporter), member 4b
chr1_-_58562129 1.64 ENSDART00000159070
slc27a1b
solute carrier family 27 (fatty acid transporter), member 1b
chr13_-_36703164 1.63 ENSDART00000044357
cdkl1
cyclin-dependent kinase-like 1 (CDC2-related kinase)
chr17_-_4395373 1.59 ENSDART00000015923
klhl10a
kelch-like family member 10a
chr7_+_568819 1.57 ENSDART00000173716
nrxn2b
neurexin 2b
chr3_-_18030938 1.56 ENSDART00000013540
si:ch73-141c7.1
si:ch73-141c7.1
chr6_+_9241121 1.54 ENSDART00000064989
pimr70
Pim proto-oncogene, serine/threonine kinase, related 70
chr7_+_529522 1.53 ENSDART00000190811
nrxn2b
neurexin 2b
chr3_+_12554801 1.51 ENSDART00000167177
ccnf
cyclin F
chr3_+_14388010 1.50 ENSDART00000171726
ENSDART00000165452
tmem56b
transmembrane protein 56b
chr5_-_1047222 1.47 ENSDART00000181112
mbd2
methyl-CpG binding domain protein 2
chr16_+_4838808 1.47 ENSDART00000179363
ibtk
inhibitor of Bruton agammaglobulinemia tyrosine kinase
chr19_-_12145765 1.45 ENSDART00000032474
pabpc1b
poly A binding protein, cytoplasmic 1 b
chr19_+_4912817 1.44 ENSDART00000101658
ENSDART00000165082
ppp1r1b
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr13_-_33683889 1.43 ENSDART00000136820
ENSDART00000065435
cst3
cystatin C (amyloid angiopathy and cerebral hemorrhage)
chr3_-_22829710 1.42 ENSDART00000055659
cyb561
cytochrome b561
chr3_-_16289826 1.40 ENSDART00000131972
bckdhbl
branched chain keto acid dehydrogenase E1, beta polypeptide, like
chr14_-_9522364 1.37 ENSDART00000054689
atoh8
atonal bHLH transcription factor 8
chr19_-_12145390 1.32 ENSDART00000143087
pabpc1b
poly A binding protein, cytoplasmic 1 b
chr12_+_49125510 1.31 ENSDART00000185804
FO704607.1

chr13_+_37022601 1.30 ENSDART00000131800
ENSDART00000041300
esr2b
estrogen receptor 2b
chr9_-_24413008 1.29 ENSDART00000135897
tmeff2a
transmembrane protein with EGF-like and two follistatin-like domains 2a
chr1_-_58561963 1.29 ENSDART00000165040
slc27a1b
solute carrier family 27 (fatty acid transporter), member 1b
chr7_-_24236364 1.27 ENSDART00000010124
slc7a8a
solute carrier family 7 (amino acid transporter light chain, L system), member 8a
chr22_+_2860260 1.23 ENSDART00000106221
si:dkey-20i20.2
si:dkey-20i20.2
chr13_-_5978433 1.21 ENSDART00000102555
actr2b
ARP2 actin related protein 2b homolog
chr14_-_24391424 1.20 ENSDART00000113376
ENSDART00000126894
fam13b
family with sequence similarity 13, member B
chr10_-_27197044 1.20 ENSDART00000137928
auts2a
autism susceptibility candidate 2a
chr25_+_19149241 1.20 ENSDART00000184982
ENSDART00000067324
mfge8b
milk fat globule-EGF factor 8 protein b
chr16_+_4839078 1.19 ENSDART00000150111
ibtk
inhibitor of Bruton agammaglobulinemia tyrosine kinase
chr5_-_40910749 1.19 ENSDART00000083467
ENSDART00000133183
parp8
poly (ADP-ribose) polymerase family, member 8
chr6_+_9893554 1.14 ENSDART00000064979
pimr74
Pim proto-oncogene, serine/threonine kinase, related 74
chr4_-_18595525 1.13 ENSDART00000049061
cdkn1ba
cyclin-dependent kinase inhibitor 1Ba
chr5_-_46273938 1.13 ENSDART00000080033
si:ch211-130m23.3
si:ch211-130m23.3
chr24_+_40473032 1.09 ENSDART00000084238
ENSDART00000178508
CABZ01076968.1

chr1_-_669717 1.09 ENSDART00000160564
cyyr1
cysteine/tyrosine-rich 1
chr13_+_41022502 1.06 ENSDART00000026808
dkk1a
dickkopf WNT signaling pathway inhibitor 1a
chr9_-_9671244 1.05 ENSDART00000018228
gsk3b
glycogen synthase kinase 3 beta
chr5_-_22619879 1.02 ENSDART00000051623
zgc:113208
zgc:113208
chr22_+_10752511 1.02 ENSDART00000081188
lsm7
LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated
chr12_-_45349849 1.01 ENSDART00000183036
CABZ01068367.1
Danio rerio uncharacterized LOC100332446 (LOC100332446), mRNA.
chr25_-_8138122 1.01 ENSDART00000104659
sergef
secretion regulating guanine nucleotide exchange factor
chr4_+_72742212 1.00 ENSDART00000171021
rab3ip
RAB3A interacting protein (rabin3)
chr17_+_43889371 1.00 ENSDART00000156871
ENSDART00000154702
msh4
mutS homolog 4
chr22_+_10752787 0.98 ENSDART00000186542
lsm7
LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated
chr6_-_43922813 0.97 ENSDART00000123341
prok2
prokineticin 2
chr3_-_16227490 0.96 ENSDART00000057159
ENSDART00000130611
ENSDART00000012835
cacnb1
calcium channel, voltage-dependent, beta 1 subunit
chr2_+_55365727 0.96 ENSDART00000162943
FP245456.1

chr1_-_51157660 0.96 ENSDART00000137172
jag1a
jagged 1a
chr1_+_144284 0.95 ENSDART00000064061
prozb
protein Z, vitamin K-dependent plasma glycoprotein b
chr4_-_15603511 0.94 ENSDART00000122520
ENSDART00000162356
chchd3a
coiled-coil-helix-coiled-coil-helix domain containing 3a
chr3_-_62380146 0.94 ENSDART00000155853
gprc5ba
G protein-coupled receptor, class C, group 5, member Ba
chr7_-_16597130 0.94 ENSDART00000144118
e2f8
E2F transcription factor 8
chr7_-_12968689 0.93 ENSDART00000173115
ENSDART00000013690
rplp2l
ribosomal protein, large P2, like
chr17_-_43466317 0.92 ENSDART00000155313
hspa4l
heat shock protein 4 like
chr7_-_18168493 0.92 ENSDART00000127428
peli3
pellino E3 ubiquitin protein ligase family member 3
chr18_-_15467446 0.92 ENSDART00000187847
endouc
endonuclease, polyU-specific C
chr18_-_50799510 0.91 ENSDART00000174373
taldo1
transaldolase 1
chr6_-_442163 0.89 ENSDART00000163564
ENSDART00000189134
ENSDART00000169789
grap2b
GRB2-related adaptor protein 2b
chr17_+_8925232 0.89 ENSDART00000036668
psmc1a
proteasome 26S subunit, ATPase 1a
chr4_-_37766174 0.88 ENSDART00000170066
si:dkey-207l24.2
si:dkey-207l24.2
chr16_+_11029762 0.88 ENSDART00000091183
erfl3
Ets2 repressor factor like 3
chr23_-_46201008 0.87 ENSDART00000160110
tgm1l4
transglutaminase 1 like 4
chr24_-_4450238 0.87 ENSDART00000066835
fzd8a
frizzled class receptor 8a
chr1_-_18803919 0.86 ENSDART00000020970
pgm2
phosphoglucomutase 2
chr10_+_10210455 0.85 ENSDART00000144214
sh2d3ca
SH2 domain containing 3Ca
chr11_-_236766 0.85 ENSDART00000163978
dusp7
dual specificity phosphatase 7
chr12_+_33919502 0.84 ENSDART00000085888
trim8b
tripartite motif containing 8b
chr22_+_13886821 0.84 ENSDART00000130585
ENSDART00000105711
sh3bp4a
SH3-domain binding protein 4a
chr5_+_51443009 0.83 ENSDART00000083350
rasgrf2b
Ras protein-specific guanine nucleotide-releasing factor 2b
chr8_+_23213320 0.83 ENSDART00000032996
ENSDART00000137536
ppdpfa
pancreatic progenitor cell differentiation and proliferation factor a
chr21_+_28445052 0.83 ENSDART00000077871
pygma
phosphorylase, glycogen, muscle A
chr15_-_47956388 0.82 ENSDART00000116506
si:ch1073-111c8.3
si:ch1073-111c8.3
chr3_-_5964557 0.82 ENSDART00000184738
BX284638.1

chr6_+_58915889 0.82 ENSDART00000083628
ddit3
DNA-damage-inducible transcript 3
chr7_-_41468942 0.82 ENSDART00000174087
smarcd3b
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3b
chr19_+_9186175 0.82 ENSDART00000039325
hcn3
hyperpolarization activated cyclic nucleotide-gated potassium channel 3
chr14_+_24283915 0.81 ENSDART00000172868
klhl3
kelch-like family member 3
chr10_-_28835771 0.81 ENSDART00000192220
ENSDART00000188436
alcama
activated leukocyte cell adhesion molecule a
chr10_+_33895315 0.81 ENSDART00000142881
fryb
furry homolog b (Drosophila)
chr20_+_16173618 0.80 ENSDART00000192109
ENSDART00000104112
ENSDART00000129633
zyg11
zyg-11 homolog (C. elegans)
chr2_-_23479714 0.79 ENSDART00000167291
si:ch211-14p21.3
si:ch211-14p21.3
chr10_+_8629275 0.78 ENSDART00000129643
aplnrb
apelin receptor b
chr16_+_46294337 0.78 ENSDART00000040769
nr2f5
nuclear receptor subfamily 2, group F, member 5
chr7_+_49664174 0.78 ENSDART00000137059
ENSDART00000131210
rassf7b
Ras association (RalGDS/AF-6) domain family (N-terminal) member 7b
chr24_+_35564668 0.77 ENSDART00000122734
cebpd
CCAAT/enhancer binding protein (C/EBP), delta
chr9_+_1654284 0.77 ENSDART00000062854
nfe2l2a
nuclear factor, erythroid 2-like 2a
chr13_-_23007813 0.77 ENSDART00000057638
hk1
hexokinase 1
chr1_-_51157454 0.76 ENSDART00000047851
jag1a
jagged 1a
chr5_+_483965 0.76 ENSDART00000150007
tek
TEK tyrosine kinase, endothelial
chr6_-_59942335 0.76 ENSDART00000168416
fbxl3b
F-box and leucine-rich repeat protein 3b
chr5_-_52784152 0.76 ENSDART00000169307
fam189a2
family with sequence similarity 189, member A2
chr8_+_2456854 0.75 ENSDART00000133938
ENSDART00000002764
polb
polymerase (DNA directed), beta
chr18_-_3166726 0.74 ENSDART00000165002
aqp11
aquaporin 11
chr23_-_44848961 0.74 ENSDART00000136839
wu:fb72h05
wu:fb72h05
chr16_+_50089417 0.74 ENSDART00000153675
nr1d2a
nuclear receptor subfamily 1, group D, member 2a
chr6_+_9421279 0.74 ENSDART00000161036
kalrnb
kalirin RhoGEF kinase b
chr22_+_1006573 0.74 ENSDART00000123458
pparda
peroxisome proliferator-activated receptor delta a
chr14_-_33454595 0.74 ENSDART00000109615
ENSDART00000173267
ENSDART00000185737
ENSDART00000190989
tmem255a
transmembrane protein 255A
chr22_-_17729778 0.74 ENSDART00000192132
si:ch73-63e15.2
si:ch73-63e15.2
chr14_+_30910114 0.73 ENSDART00000187166
ENSDART00000078187
foxo4
forkhead box O4
chr12_+_695619 0.73 ENSDART00000161691
abcc3
ATP-binding cassette, sub-family C (CFTR/MRP), member 3
chr11_-_236984 0.73 ENSDART00000170778
dusp7
dual specificity phosphatase 7
chr25_+_37443194 0.73 ENSDART00000163178
ENSDART00000190262
slc10a3
solute carrier family 10, member 3
chr20_+_13894123 0.73 ENSDART00000007744
slc30a1a
solute carrier family 30 (zinc transporter), member 1a
chr19_-_9472893 0.73 ENSDART00000045565
ENSDART00000137505
vamp1
vesicle-associated membrane protein 1
chr7_-_16596938 0.73 ENSDART00000134548
e2f8
E2F transcription factor 8
chr15_-_21837207 0.72 ENSDART00000089953
sik2b
salt-inducible kinase 2b
chr19_-_44091405 0.71 ENSDART00000132800
rad21b
RAD21 cohesin complex component b
chr20_+_33294428 0.71 ENSDART00000024104
mycn
MYCN proto-oncogene, bHLH transcription factor
chr3_-_33417826 0.71 ENSDART00000084284
abi3a
ABI family, member 3a
chr15_-_20468302 0.70 ENSDART00000018514
dlc
deltaC
chr23_-_40817792 0.69 ENSDART00000136343
si:dkeyp-27c8.1
si:dkeyp-27c8.1
chr24_+_42131564 0.69 ENSDART00000153854
wwp1
WW domain containing E3 ubiquitin protein ligase 1
chr3_+_36284986 0.69 ENSDART00000059533
wipi1
WD repeat domain, phosphoinositide interacting 1
chr1_-_411331 0.68 ENSDART00000092524
rasa3
RAS p21 protein activator 3
chr4_+_57093908 0.66 ENSDART00000170198
si:ch211-238e22.5
si:ch211-238e22.5
chr5_-_2689753 0.66 ENSDART00000172699
gng10
guanine nucleotide binding protein (G protein), gamma 10
chr22_-_607812 0.66 ENSDART00000145983
cdkn1a
cyclin-dependent kinase inhibitor 1A
chr3_+_5575313 0.65 ENSDART00000134693
ENSDART00000101807
si:ch211-106h11.3
si:ch211-106h11.3
chr22_-_367569 0.65 ENSDART00000041895
ssu72
SSU72 homolog, RNA polymerase II CTD phosphatase
chr19_+_48251273 0.64 ENSDART00000157424
CU693379.1

chr3_+_22079219 0.64 ENSDART00000122782
kansl1b
KAT8 regulatory NSL complex subunit 1b
chr22_+_26703026 0.64 ENSDART00000158756
crebbpa
CREB binding protein a
chr18_+_36625490 0.63 ENSDART00000148032
clasrp
CLK4-associating serine/arginine rich protein
chr13_-_45523026 0.63 ENSDART00000020663
rhd
Rh blood group, D antigen
chr2_+_24177006 0.62 ENSDART00000132582
map4l
microtubule associated protein 4 like
chr1_-_39943596 0.62 ENSDART00000149730
stox2a
storkhead box 2a
chr25_-_37331513 0.61 ENSDART00000111862
ldlrad3
low density lipoprotein receptor class A domain containing 3
chr15_-_5742531 0.61 ENSDART00000045985
phkg1a
phosphorylase kinase, gamma 1a (muscle)
chr8_+_1187928 0.61 ENSDART00000127252
slc35d2
solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2
chr4_+_1600034 0.61 ENSDART00000146779
slc38a2
solute carrier family 38, member 2
chr17_-_53329704 0.61 ENSDART00000193895
exd1
exonuclease 3'-5' domain containing 1
chr5_-_1047504 0.59 ENSDART00000159346
mbd2
methyl-CpG binding domain protein 2
chr15_-_47857687 0.59 ENSDART00000098982
ENSDART00000151594
h3f3b.1
H3 histone, family 3B.1
chr19_+_156757 0.59 ENSDART00000167717
carmil1
capping protein regulator and myosin 1 linker 1
chr20_-_16156419 0.58 ENSDART00000037420
ralgps2
Ral GEF with PH domain and SH3 binding motif 2
chr14_-_6225336 0.58 ENSDART00000111681
hdx
highly divergent homeobox
chr20_-_54381034 0.58 ENSDART00000136779
entpd5b
ectonucleoside triphosphate diphosphohydrolase 5b
chr22_-_5441893 0.58 ENSDART00000161421
zgc:194627
zgc:194627
chr6_-_54078623 0.58 ENSDART00000154076
hyal1
hyaluronoglucosaminidase 1
chr15_+_19293744 0.57 ENSDART00000184994
ENSDART00000123815
jam3a
junctional adhesion molecule 3a
chr25_-_36492779 0.57 ENSDART00000042271
irx3b
iroquois homeobox 3b
chr12_-_48671612 0.57 ENSDART00000007202
zgc:92749
zgc:92749
chr25_+_17313568 0.57 ENSDART00000125459
cnot1
CCR4-NOT transcription complex, subunit 1
chr20_+_18740518 0.56 ENSDART00000142196
fam167ab
family with sequence similarity 167, member Ab
chr9_+_993477 0.55 ENSDART00000182045
CABZ01066921.1

chr7_-_66877058 0.55 ENSDART00000155954
adma
adrenomedullin a
chr18_+_36770166 0.55 ENSDART00000078151
fosb
FBJ murine osteosarcoma viral oncogene homolog B
chr1_+_54908895 0.55 ENSDART00000145652
golga7ba
golgin A7 family, member Ba
chr4_-_9852318 0.55 ENSDART00000080702
glt8d2
glycosyltransferase 8 domain containing 2
chr18_-_22414565 0.54 ENSDART00000079158
tmem170a
transmembrane protein 170A
chr9_-_8454060 0.54 ENSDART00000110158
irs2b
insulin receptor substrate 2b
chr2_+_24177190 0.53 ENSDART00000099546
map4l
microtubule associated protein 4 like
chr23_+_14217508 0.53 ENSDART00000143618
birc7
baculoviral IAP repeat containing 7
chr19_-_7450796 0.52 ENSDART00000104750
mllt11
MLLT11, transcription factor 7 cofactor
chr17_+_53418445 0.52 ENSDART00000097631
slc9a1b
solute carrier family 9 member A1b
chr4_-_23839789 0.52 ENSDART00000143571
usp6nl
USP6 N-terminal like
chr18_-_3464222 0.51 ENSDART00000166980
myo7aa
myosin VIIAa
chr5_+_22969651 0.51 ENSDART00000089992
ENSDART00000145477
hmgn7
high mobility group nucleosomal binding domain 7
chr21_-_308852 0.51 ENSDART00000151613
lhfpl2a
LHFPL tetraspan subfamily member 2a
chr18_+_507618 0.51 ENSDART00000159464
nedd4a
neural precursor cell expressed, developmentally down-regulated 4a
chr16_-_52733384 0.50 ENSDART00000147236
ENSDART00000056101
azin1a
antizyme inhibitor 1a
chr11_-_497854 0.50 ENSDART00000104520
cnbpb
CCHC-type zinc finger, nucleic acid binding protein b
chr13_+_4405282 0.50 ENSDART00000148280
prr18
proline rich 18
chr25_+_150570 0.49 ENSDART00000170892
adam10b
ADAM metallopeptidase domain 10b
chr18_-_7810214 0.49 ENSDART00000139505
ENSDART00000139188
shank3a
SH3 and multiple ankyrin repeat domains 3a
chr2_-_42065069 0.49 ENSDART00000140188
cspp1b
centrosome and spindle pole associated protein 1b
chr16_-_8613499 0.49 ENSDART00000189189
cobl
cordon-bleu WH2 repeat protein
chr11_+_40831620 0.49 ENSDART00000160023
errfi1a
ERBB receptor feedback inhibitor 1a

Network of associatons between targets according to the STRING database.

First level regulatory network of sp3b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 4.8 GO:0033301 cell cycle comprising mitosis without cytokinesis(GO:0033301)
0.6 2.9 GO:0071071 heat generation(GO:0031649) regulation of heat generation(GO:0031650) positive regulation of heat generation(GO:0031652) regulation of phospholipid biosynthetic process(GO:0071071) negative regulation of phospholipid biosynthetic process(GO:0071072)
0.6 4.0 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.6 1.7 GO:0007571 age-dependent general metabolic decline(GO:0007571)
0.5 1.4 GO:2001014 regulation of skeletal muscle cell differentiation(GO:2001014)
0.3 1.7 GO:0046677 response to antibiotic(GO:0046677)
0.3 2.3 GO:0021885 forebrain cell migration(GO:0021885)
0.3 0.9 GO:0021531 spinal cord radial glial cell differentiation(GO:0021531) eye field cell fate commitment involved in camera-type eye formation(GO:0060898)
0.3 0.8 GO:0052576 carbohydrate localization(GO:0052575) carbohydrate storage(GO:0052576)
0.3 1.9 GO:0098773 skin epidermis development(GO:0098773)
0.3 0.8 GO:0072156 distal tubule morphogenesis(GO:0072156)
0.3 1.9 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.3 1.3 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.3 1.8 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.2 0.7 GO:0010312 detoxification of zinc ion(GO:0010312) stress response to zinc ion(GO:1990359)
0.2 4.1 GO:0001539 cilium or flagellum-dependent cell motility(GO:0001539) cilium-dependent cell motility(GO:0060285)
0.2 0.6 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.2 0.8 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.2 0.8 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.2 0.6 GO:2000812 regulation of barbed-end actin filament capping(GO:2000812)
0.2 0.8 GO:1903587 regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587) positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903589)
0.2 1.5 GO:0010826 negative regulation of centrosome duplication(GO:0010826) negative regulation of centrosome cycle(GO:0046606)
0.2 0.9 GO:0008592 regulation of Toll signaling pathway(GO:0008592)
0.2 0.5 GO:0090200 regulation of release of cytochrome c from mitochondria(GO:0090199) positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.2 0.9 GO:2000767 positive regulation of cytoplasmic translation(GO:2000767)
0.2 2.1 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.2 1.1 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.2 1.9 GO:0030520 intracellular estrogen receptor signaling pathway(GO:0030520)
0.2 1.2 GO:1905168 positive regulation of double-strand break repair via homologous recombination(GO:1905168) regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.1 2.0 GO:0036158 outer dynein arm assembly(GO:0036158)
0.1 0.9 GO:0097107 postsynaptic density assembly(GO:0097107) modulation of excitatory postsynaptic potential(GO:0098815) positive regulation of excitatory postsynaptic potential(GO:2000463)
0.1 1.9 GO:2000601 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 1.9 GO:0046051 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.1 0.5 GO:1902590 virion assembly(GO:0019068) virus maturation(GO:0019075) multi-organism membrane organization(GO:0044803) viral budding(GO:0046755) multi-organism organelle organization(GO:1902590) multi-organism membrane budding(GO:1902592)
0.1 0.7 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.1 1.6 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 0.4 GO:0097037 heme export(GO:0097037)
0.1 2.0 GO:0030878 thyroid gland development(GO:0030878)
0.1 0.3 GO:0035751 regulation of lysosomal lumen pH(GO:0035751)
0.1 1.7 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208) peripheral nervous system neuron axonogenesis(GO:0048936)
0.1 0.5 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.1 3.8 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.1 1.0 GO:0000710 meiotic mismatch repair(GO:0000710)
0.1 1.0 GO:0034694 response to prostaglandin(GO:0034694)
0.1 0.1 GO:0048389 intermediate mesoderm development(GO:0048389)
0.1 0.8 GO:0032986 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.1 0.7 GO:0043363 nucleate erythrocyte differentiation(GO:0043363)
0.1 0.3 GO:0019242 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.1 0.4 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.1 0.6 GO:0035777 pronephric distal tubule development(GO:0035777)
0.1 0.7 GO:0010887 negative regulation of cholesterol storage(GO:0010887)
0.1 1.0 GO:0030431 sleep(GO:0030431)
0.1 0.7 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.1 0.6 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.1 1.6 GO:1901663 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.1 0.2 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
0.1 0.3 GO:0030859 polarized epithelial cell differentiation(GO:0030859)
0.1 0.4 GO:0035332 positive regulation of hippo signaling(GO:0035332)
0.1 0.4 GO:0010591 regulation of lamellipodium assembly(GO:0010591)
0.1 0.5 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.1 0.1 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228) protein localization to nuclear envelope(GO:0090435)
0.1 0.4 GO:0010801 regulation of peptidyl-threonine phosphorylation(GO:0010799) negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.1 0.2 GO:1905132 meiotic cell cycle phase transition(GO:0044771) metaphase/anaphase transition of meiotic cell cycle(GO:0044785) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994) regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902102) negative regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902103) regulation of meiotic chromosome separation(GO:1905132) negative regulation of meiotic chromosome separation(GO:1905133)
0.1 0.6 GO:0006868 glutamine transport(GO:0006868)
0.1 0.4 GO:0031507 heterochromatin assembly(GO:0031507)
0.1 0.4 GO:0008206 bile acid biosynthetic process(GO:0006699) bile acid metabolic process(GO:0008206)
0.1 1.0 GO:0051156 glucose 6-phosphate metabolic process(GO:0051156)
0.1 0.7 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.1 1.2 GO:0021884 forebrain neuron development(GO:0021884)
0.1 0.5 GO:0046546 development of primary male sexual characteristics(GO:0046546)
0.1 1.1 GO:0070654 sensory epithelium regeneration(GO:0070654) epithelium regeneration(GO:1990399)
0.1 0.4 GO:0010002 cardioblast differentiation(GO:0010002)
0.1 0.7 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.1 0.7 GO:0035493 SNARE complex assembly(GO:0035493)
0.1 0.3 GO:0010482 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.0 1.3 GO:0015804 neutral amino acid transport(GO:0015804)
0.0 0.2 GO:0032207 regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208)
0.0 1.4 GO:0007007 inner mitochondrial membrane organization(GO:0007007)
0.0 0.2 GO:0036268 swimming(GO:0036268)
0.0 0.5 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.0 0.8 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.0 0.6 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 2.1 GO:0006096 glycolytic process(GO:0006096)
0.0 0.9 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.1 GO:0034375 high-density lipoprotein particle remodeling(GO:0034375)
0.0 0.9 GO:0060232 delamination(GO:0060232)
0.0 0.7 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.0 0.4 GO:0042135 neurotransmitter catabolic process(GO:0042135)
0.0 0.1 GO:0090183 regulation of morphogenesis of a branching structure(GO:0060688) positive regulation of mesonephros development(GO:0061213) regulation of mesonephros development(GO:0061217) regulation of kidney development(GO:0090183) positive regulation of kidney development(GO:0090184) regulation of branching involved in ureteric bud morphogenesis(GO:0090189) positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.0 0.2 GO:0042427 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.0 0.4 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.9 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.0 0.2 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 0.8 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 0.2 GO:0071881 adenylate cyclase-inhibiting adrenergic receptor signaling pathway(GO:0071881)
0.0 1.0 GO:0032526 response to retinoic acid(GO:0032526)
0.0 0.7 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.0 0.6 GO:0009134 nucleoside diphosphate catabolic process(GO:0009134)
0.0 0.1 GO:0051012 microtubule sliding(GO:0051012)
0.0 0.1 GO:0014814 regulation of synaptic growth at neuromuscular junction(GO:0008582) axon regeneration at neuromuscular junction(GO:0014814) positive regulation of synaptic growth at neuromuscular junction(GO:0045887)
0.0 1.0 GO:0060122 inner ear receptor stereocilium organization(GO:0060122)
0.0 0.5 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 0.6 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.7 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 0.2 GO:2000765 regulation of cytoplasmic translation(GO:2000765) negative regulation of cytoplasmic translation(GO:2000766)
0.0 1.2 GO:0032402 melanosome transport(GO:0032402) pigment granule transport(GO:0051904)
0.0 0.4 GO:0061001 regulation of dendritic spine morphogenesis(GO:0061001)
0.0 0.2 GO:1902047 polyamine transport(GO:0015846) polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267) positive regulation of polyamine transmembrane transport(GO:1902269)
0.0 0.4 GO:1903286 positive regulation of sodium ion transport(GO:0010765) positive regulation of sodium ion transmembrane transport(GO:1902307) regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288) positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.0 0.3 GO:0070932 histone H3 deacetylation(GO:0070932)
0.0 0.6 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.1 GO:0051792 medium-chain fatty acid biosynthetic process(GO:0051792)
0.0 2.7 GO:0000956 nuclear-transcribed mRNA catabolic process(GO:0000956)
0.0 0.1 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.0 0.4 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.3 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.1 GO:0030219 megakaryocyte differentiation(GO:0030219)
0.0 0.7 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.0 0.2 GO:0021754 facial nucleus development(GO:0021754)
0.0 0.1 GO:0019240 citrulline biosynthetic process(GO:0019240)
0.0 2.8 GO:0001708 cell fate specification(GO:0001708)
0.0 0.1 GO:1902259 regulation of delayed rectifier potassium channel activity(GO:1902259)
0.0 0.8 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 0.2 GO:0061384 trabecula morphogenesis(GO:0061383) heart trabecula morphogenesis(GO:0061384)
0.0 0.8 GO:0060536 cartilage morphogenesis(GO:0060536)
0.0 0.8 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.0 1.4 GO:0022900 electron transport chain(GO:0022900)
0.0 0.7 GO:0050727 regulation of inflammatory response(GO:0050727)
0.0 0.5 GO:0001843 neural tube closure(GO:0001843) tube closure(GO:0060606)
0.0 0.4 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.2 GO:0007608 sensory perception of smell(GO:0007608)
0.0 0.3 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471)
0.0 0.5 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.2 GO:0021772 olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988)
0.0 0.4 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.5 GO:0031398 positive regulation of protein ubiquitination(GO:0031398)
0.0 0.3 GO:0030007 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.0 0.5 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.4 GO:0060037 pharyngeal system development(GO:0060037)
0.0 0.5 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0 0.2 GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation(GO:0050732) negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0 0.3 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.2 GO:0090481 pyrimidine nucleotide-sugar transport(GO:0015781) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.0 0.2 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 0.1 GO:1901315 regulation of histone ubiquitination(GO:0033182) negative regulation of histone ubiquitination(GO:0033183) regulation of protein K63-linked ubiquitination(GO:1900044) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) regulation of protein polyubiquitination(GO:1902914) negative regulation of protein polyubiquitination(GO:1902915)
0.0 1.0 GO:0007596 blood coagulation(GO:0007596)
0.0 0.3 GO:0007548 sex differentiation(GO:0007548)
0.0 0.4 GO:0032869 cellular response to insulin stimulus(GO:0032869)
0.0 0.1 GO:0098719 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.2 GO:0001556 oocyte maturation(GO:0001556)
0.0 0.2 GO:0090309 methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.2 GO:0008354 germ cell migration(GO:0008354)
0.0 0.4 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.4 GO:0042129 regulation of T cell proliferation(GO:0042129)
0.0 0.3 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0 0.3 GO:0032482 Rab protein signal transduction(GO:0032482)
0.0 0.4 GO:0042149 cellular response to glucose starvation(GO:0042149)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.3 2.0 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.3 1.0 GO:0070319 Golgi to plasma membrane transport vesicle(GO:0070319)
0.2 2.2 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
0.2 1.3 GO:0070062 extracellular exosome(GO:0070062)
0.2 2.0 GO:0036157 outer dynein arm(GO:0036157)
0.1 1.4 GO:0061617 MICOS complex(GO:0061617)
0.1 0.6 GO:1990923 PET complex(GO:1990923)
0.1 1.9 GO:0031209 SCAR complex(GO:0031209)
0.1 0.7 GO:0034991 nuclear cohesin complex(GO:0000798) mitotic cohesin complex(GO:0030892) nuclear mitotic cohesin complex(GO:0034990) nuclear meiotic cohesin complex(GO:0034991)
0.1 1.8 GO:0043209 myelin sheath(GO:0043209)
0.1 0.5 GO:0018444 translation release factor complex(GO:0018444)
0.1 0.4 GO:0008290 F-actin capping protein complex(GO:0008290)
0.1 0.7 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 0.2 GO:0010369 chromocenter(GO:0010369)
0.1 1.2 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.1 0.9 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.1 0.3 GO:0033553 rDNA heterochromatin(GO:0033553)
0.1 1.0 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.1 1.0 GO:0000795 synaptonemal complex(GO:0000795)
0.1 0.5 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024) nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.1 3.8 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 0.8 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.1 1.0 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 0.6 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.6 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.6 GO:0044545 NSL complex(GO:0044545)
0.0 0.6 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.5 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.0 4.9 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.4 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 2.8 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.1 GO:0008247 1-alkyl-2-acetylglycerophosphocholine esterase complex(GO:0008247)
0.0 0.1 GO:0044611 nuclear pore inner ring(GO:0044611)
0.0 1.2 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.5 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.8 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.1 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.3 GO:0005869 dynactin complex(GO:0005869)
0.0 0.4 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 1.7 GO:0036064 ciliary basal body(GO:0036064)
0.0 0.7 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.4 GO:0035102 PRC1 complex(GO:0035102)
0.0 5.5 GO:0005874 microtubule(GO:0005874)
0.0 1.3 GO:0030027 lamellipodium(GO:0030027)
0.0 0.4 GO:0048788 cytoskeleton of presynaptic active zone(GO:0048788)
0.0 0.2 GO:0070187 telosome(GO:0070187)
0.0 0.0 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.0 0.3 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 1.4 GO:0016607 nuclear speck(GO:0016607)
0.0 0.7 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.2 GO:0048179 activin receptor complex(GO:0048179)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.3 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.8 4.0 GO:0070412 R-SMAD binding(GO:0070412)
0.6 1.7 GO:0003721 telomerase RNA reverse transcriptase activity(GO:0003721)
0.5 4.4 GO:0001130 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.5 2.1 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.5 1.4 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.4 2.9 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.2 1.8 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.2 1.3 GO:0016744 transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
0.2 1.3 GO:1903924 estradiol binding(GO:1903924)
0.2 1.1 GO:0039706 co-receptor binding(GO:0039706)
0.2 1.9 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.2 1.6 GO:0048039 ubiquinone binding(GO:0048039)
0.2 0.8 GO:0008184 phosphorylase activity(GO:0004645) glycogen phosphorylase activity(GO:0008184)
0.2 0.8 GO:0070004 cysteine-type exopeptidase activity(GO:0070004)
0.2 0.5 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.2 0.8 GO:0060182 apelin receptor activity(GO:0060182)
0.2 2.2 GO:0008327 methyl-CpG binding(GO:0008327)
0.2 0.6 GO:0005461 UDP-glucuronic acid transmembrane transporter activity(GO:0005461) UDP-N-acetylgalactosamine transmembrane transporter activity(GO:0005463)
0.1 0.9 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.1 1.7 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.1 0.9 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.1 0.8 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) glucose binding(GO:0005536) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 3.8 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 0.6 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.1 0.7 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 1.6 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 2.2 GO:0001671 ATPase activator activity(GO:0001671)
0.1 2.7 GO:0005112 Notch binding(GO:0005112)
0.1 0.4 GO:0097108 hedgehog family protein binding(GO:0097108)
0.1 0.6 GO:0030331 estrogen receptor binding(GO:0030331) retinoic acid receptor binding(GO:0042974)
0.1 0.6 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.1 2.1 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.1 1.4 GO:0033691 sialic acid binding(GO:0033691)
0.1 0.3 GO:0004807 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
0.1 0.4 GO:0034046 poly(G) binding(GO:0034046)
0.1 0.3 GO:0035671 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) enone reductase activity(GO:0035671) cholestenone 5-alpha-reductase activity(GO:0047751)
0.1 4.5 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 0.4 GO:0008131 primary amine oxidase activity(GO:0008131)
0.1 0.6 GO:0008420 CTD phosphatase activity(GO:0008420)
0.1 0.9 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.1 0.2 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.1 0.2 GO:1902945 metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902945)
0.1 1.9 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.1 0.1 GO:0016743 carboxyl- or carbamoyltransferase activity(GO:0016743)
0.1 2.0 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.1 0.2 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
0.1 0.4 GO:0015232 heme transporter activity(GO:0015232)
0.1 1.0 GO:0030983 mismatched DNA binding(GO:0030983)
0.1 0.4 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 0.8 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.6 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.7 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 1.0 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.2 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.0 0.4 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0 0.5 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.6 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 1.3 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 0.9 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.1 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.0 1.6 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.3 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 2.4 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.6 GO:0045134 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.0 0.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.7 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.1 GO:1904121 phosphatidylethanolamine transporter activity(GO:1904121)
0.0 0.3 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.2 GO:0034061 DNA polymerase activity(GO:0034061)
0.0 0.2 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.0 0.1 GO:0030116 glial cell-derived neurotrophic factor receptor binding(GO:0030116)
0.0 0.2 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.4 GO:0019870 chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.0 0.4 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.6 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.7 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 1.0 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.7 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.1 GO:0070548 L-glutamine aminotransferase activity(GO:0070548)
0.0 0.3 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.5 GO:0003785 actin monomer binding(GO:0003785)
0.0 1.3 GO:0030295 kinase activator activity(GO:0019209) protein kinase activator activity(GO:0030295)
0.0 1.6 GO:0016879 ligase activity, forming carbon-nitrogen bonds(GO:0016879)
0.0 0.7 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.2 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.0 0.3 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.8 GO:0005272 sodium channel activity(GO:0005272)
0.0 0.4 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.7 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.9 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.3 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.2 GO:0005221 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.4 GO:0022842 leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.0 1.0 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 0.2 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.3 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.2 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.9 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.3 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.5 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.1 GO:0015385 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0 0.1 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.2 GO:0017002 activin-activated receptor activity(GO:0017002)
0.0 2.3 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 1.0 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.4 GO:0005109 frizzled binding(GO:0005109)
0.0 0.1 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 1.8 GO:0042802 identical protein binding(GO:0042802)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 1.7 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.1 1.1 PID REELIN PATHWAY Reelin signaling pathway
0.1 2.0 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.7 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 2.2 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 2.6 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.8 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 1.6 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.3 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.3 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.2 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.5 PID SHP2 PATHWAY SHP2 signaling
0.0 2.0 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.4 PID LKB1 PATHWAY LKB1 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.0 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.2 2.1 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.2 1.7 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 1.6 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.1 2.1 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 0.7 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 1.4 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 2.8 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 3.6 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 1.4 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 0.9 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.1 0.4 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1 0.6 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.1 0.9 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 0.7 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.1 0.9 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 1.0 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.1 1.7 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 2.0 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 1.7 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 0.4 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.7 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.3 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.8 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 1.0 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.3 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.8 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.4 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.0 0.3 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.2 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.1 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.9 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 0.8 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.3 REACTOME SIGNALING BY EGFR IN CANCER Genes involved in Signaling by EGFR in Cancer
0.0 0.9 REACTOME INTEGRATION OF ENERGY METABOLISM Genes involved in Integration of energy metabolism
0.0 1.0 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.6 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.9 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.0 0.2 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.1 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors