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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for stat3

Z-value: 0.25

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Transcription factors associated with stat3

Gene Symbol Gene ID Gene Info
stat3
ENSDARG00000022712 signal transducer and activator of transcription 3 (acute-phase response factor)

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
stat3dr11_v1_chr3_+_17030665_170307040.068.3e-01Click!

Activity profile of stat3 motif

Sorted Z-values of stat3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_17964525 0.95 ENSDART00000018948
cishb
cytokine inducible SH2-containing protein b
chr24_+_31361407 0.75 ENSDART00000162668
cremb
cAMP responsive element modulator b
chr1_-_51734524 0.63 ENSDART00000109640
ENSDART00000122628
junba
JunB proto-oncogene, AP-1 transcription factor subunit a
chr6_-_40352215 0.63 ENSDART00000103992
ttll3
tubulin tyrosine ligase-like family, member 3
chr3_+_39922602 0.61 ENSDART00000193937
cacna1ha
calcium channel, voltage-dependent, T type, alpha 1H subunit a
chr24_-_37568359 0.59 ENSDART00000056286
h1f0
H1 histone family, member 0
chr22_+_36914636 0.57 ENSDART00000150948
pimr205
Pim proto-oncogene, serine/threonine kinase, related 205
chr13_-_37608441 0.52 ENSDART00000140230
zgc:123068
zgc:123068
chr21_+_35215810 0.50 ENSDART00000135256
ubtd2
ubiquitin domain containing 2
chr19_+_17385561 0.48 ENSDART00000141397
ENSDART00000143913
ENSDART00000133626
rpl15
ribosomal protein L15
chr18_-_21177674 0.47 ENSDART00000060175
si:dkey-12e7.4
si:dkey-12e7.4
chr13_-_37642890 0.47 ENSDART00000146483
ENSDART00000136071
ENSDART00000111786
si:dkey-188i13.9
si:dkey-188i13.9
chr9_+_48219111 0.47 ENSDART00000111225
ENSDART00000145972
ccdc173
coiled-coil domain containing 173
chr14_-_30747686 0.47 ENSDART00000008373
fosl1a
FOS-like antigen 1a
chr1_-_9114936 0.47 ENSDART00000163624
ENSDART00000132910
si:ch211-14k19.8
vap
si:ch211-14k19.8
vascular associated protein
chr9_+_40825065 0.44 ENSDART00000137673
si:dkey-95p16.2
si:dkey-95p16.2
chr3_-_35541378 0.43 ENSDART00000183075
ENSDART00000022147
ndufab1b
NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1b
chr23_-_19715799 0.41 ENSDART00000142072
ENSDART00000032744
ENSDART00000131860
rpl10
ribosomal protein L10
chr7_+_32369026 0.40 ENSDART00000169588
lgr4
leucine-rich repeat containing G protein-coupled receptor 4
chr19_+_712127 0.39 ENSDART00000093281
ENSDART00000180002
ENSDART00000146050
fhod3a
formin homology 2 domain containing 3a
chr8_-_7502166 0.38 ENSDART00000176938
cdk20
cyclin-dependent kinase 20
chr3_-_31655796 0.38 ENSDART00000181052
CU062431.1

chr14_+_11395383 0.38 ENSDART00000106657
glod5
glyoxalase domain containing 5
chr16_-_35394422 0.38 ENSDART00000180593
si:dkey-34d22.3
si:dkey-34d22.3
chr17_+_40989973 0.37 ENSDART00000160049
mrpl33
mitochondrial ribosomal protein L33
chr16_-_12809873 0.37 ENSDART00000146997
ENSDART00000178291
ENSDART00000007842
isoc2
isochorismatase domain containing 2
chr21_-_30545121 0.36 ENSDART00000019199
rab39ba
RAB39B, member RAS oncogene family a
chr3_-_22829710 0.35 ENSDART00000055659
cyb561
cytochrome b561
chr3_+_26734162 0.35 ENSDART00000114552
si:dkey-202l16.5
si:dkey-202l16.5
chr16_+_40560622 0.34 ENSDART00000038294
tp53inp1
tumor protein p53 inducible nuclear protein 1
chr4_-_18436899 0.34 ENSDART00000141671
socs2
suppressor of cytokine signaling 2
chr1_-_46981134 0.34 ENSDART00000130607
pknox1.2
pbx/knotted 1 homeobox 1.2
chr3_-_57425961 0.33 ENSDART00000033716
socs3a
suppressor of cytokine signaling 3a
chr22_+_7480465 0.33 ENSDART00000034545
CELA1 (1 of many)
zgc:92745
chr20_-_35841570 0.33 ENSDART00000037855
tnfrsf21
tumor necrosis factor receptor superfamily, member 21
chr6_+_43015916 0.31 ENSDART00000064888
tcta
T cell leukemia translocation altered
chr3_+_59899452 0.31 ENSDART00000064311
arhgdia
Rho GDP dissociation inhibitor (GDI) alpha
chr21_+_8341774 0.30 ENSDART00000129749
ENSDART00000055325
ENSDART00000133804
psmb7
proteasome subunit beta 7
chr18_+_3332999 0.29 ENSDART00000160857
gdpd4a
glycerophosphodiester phosphodiesterase domain containing 4a
chr3_-_13461056 0.28 ENSDART00000137678
fbxw9
F-box and WD repeat domain containing 9
chr17_+_7522777 0.28 ENSDART00000184723
klhl10b.2
kelch-like family member 10b, tandem duplicate 2
chr16_+_54513267 0.27 ENSDART00000161923
CABZ01088508.1

chr10_-_3332362 0.27 ENSDART00000007577
ENSDART00000055140
tor4aa
torsin family 4, member Aa
chr14_-_28567845 0.26 ENSDART00000126095
insb
preproinsulin b
chr19_+_5418006 0.26 ENSDART00000132874
eif1b
eukaryotic translation initiation factor 1B
chr6_+_33897624 0.26 ENSDART00000166706
ccdc17
coiled-coil domain containing 17
chr16_+_31922065 0.26 ENSDART00000131661
ENSDART00000144194
ENSDART00000145510
rps9
ribosomal protein S9
chr1_-_26398361 0.26 ENSDART00000160183
ppa2
pyrophosphatase (inorganic) 2
chr11_-_6265574 0.26 ENSDART00000181974
ENSDART00000104405
ccl25b
chemokine (C-C motif) ligand 25b
chr3_+_472158 0.25 ENSDART00000134971
zgc:194659
zgc:194659
chr19_+_47783137 0.25 ENSDART00000024777
ENSDART00000158979
c19h1orf109
c19h1orf109 homolog (H. sapiens)
chr23_-_40792128 0.25 ENSDART00000145360
si:dkey-194e6.2
si:dkey-194e6.2
chr13_+_6092135 0.24 ENSDART00000162738
fam120b
family with sequence similarity 120B
chr16_+_31921812 0.24 ENSDART00000176928
ENSDART00000193733
rps9
ribosomal protein S9
chr24_+_5208171 0.24 ENSDART00000155926
ENSDART00000154464
si:ch73-206p6.1
si:ch73-206p6.1
chr9_+_26103814 0.23 ENSDART00000026011
efnb2a
ephrin-B2a
chr13_-_49819027 0.23 ENSDART00000067824
b3galnt2
beta-1,3-N-acetylgalactosaminyltransferase 2
chr15_-_29510074 0.22 ENSDART00000184070
BX324227.3

chr12_-_19346678 0.22 ENSDART00000044860
maff
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
chr24_-_37472727 0.22 ENSDART00000134152
cluap1
clusterin associated protein 1
chr17_+_25397070 0.21 ENSDART00000164254
zgc:154055
zgc:154055
chr1_+_30083578 0.21 ENSDART00000101779
ENSDART00000143639
vps8
vacuolar protein sorting 8 homolog (S. cerevisiae)
chr20_+_52458765 0.21 ENSDART00000057980
tsta3
tissue specific transplantation antigen P35B
chr3_-_13461361 0.21 ENSDART00000080807
fbxw9
F-box and WD repeat domain containing 9
chr14_+_11457500 0.20 ENSDART00000169202
si:ch211-153b23.5
si:ch211-153b23.5
chr7_+_32369463 0.20 ENSDART00000180544
lgr4
leucine-rich repeat containing G protein-coupled receptor 4
chr1_-_10071422 0.20 ENSDART00000135522
ENSDART00000033118
fga
fibrinogen alpha chain
chr25_+_34246625 0.20 ENSDART00000082578
bnip2
BCL2 interacting protein 2
chr5_+_15819651 0.19 ENSDART00000081230
ENSDART00000186969
ENSDART00000134206
hspb8
heat shock protein b8
chr4_-_12323228 0.19 ENSDART00000081089
il17ra1a
interleukin 17 receptor A1a
chr6_+_22679610 0.18 ENSDART00000102701
zmp:0000000634
zmp:0000000634
chr20_-_47188966 0.18 ENSDART00000152965
si:dkeyp-104f11.9
si:dkeyp-104f11.9
chr3_+_4502066 0.18 ENSDART00000088610
rangap1a
RAN GTPase activating protein 1a
chr1_-_17711636 0.18 ENSDART00000148322
ENSDART00000122670
ufsp2
ufm1-specific peptidase 2
chr24_+_16149514 0.18 ENSDART00000152087
si:dkey-118j18.2
si:dkey-118j18.2
chr24_+_16149251 0.18 ENSDART00000188289
si:dkey-118j18.2
si:dkey-118j18.2
chr2_+_26288301 0.17 ENSDART00000017668
ptbp1a
polypyrimidine tract binding protein 1a
chr22_-_15578402 0.17 ENSDART00000062986
hsh2d
hematopoietic SH2 domain containing
chr22_-_834106 0.17 ENSDART00000105873
cry4
cryptochrome circadian clock 4
chr22_+_20427170 0.17 ENSDART00000136744
foxq2
forkhead box Q2
chr20_-_23440955 0.17 ENSDART00000153386
slc10a4
solute carrier family 10, member 4
chr10_-_4375190 0.17 ENSDART00000016102
CABZ01073795.1

chr2_+_17181777 0.17 ENSDART00000112063
ptger4c
prostaglandin E receptor 4 (subtype EP4) c
chr19_+_43359075 0.16 ENSDART00000148287
ENSDART00000149856
ENSDART00000188236
ENSDART00000136695
ENSDART00000193859
yrk
Yes-related kinase
chr4_+_359970 0.16 ENSDART00000139832
tmem181
transmembrane protein 181
chr21_+_45626136 0.16 ENSDART00000158742
irf1b
interferon regulatory factor 1b
chr17_+_10318071 0.16 ENSDART00000161844
foxa1
forkhead box A1
chr7_-_22941472 0.16 ENSDART00000190334
tnfsf10l
TNF superfamily member 10, like
chr21_+_13150937 0.16 ENSDART00000102251
sptan1
spectrin alpha, non-erythrocytic 1
chr21_-_5879897 0.16 ENSDART00000184034
rpl35
ribosomal protein L35
chr1_+_5402476 0.16 ENSDART00000040204
tuba8l2
tubulin, alpha 8 like 2
chr12_-_32013125 0.15 ENSDART00000153355
grin2cb
glutamate receptor, ionotropic, N-methyl D-aspartate 2Cb
chr19_-_41405187 0.15 ENSDART00000038038
ENSDART00000172350
sem1
SEM1, 26S proteasome complex subunit
chr8_+_20918207 0.15 ENSDART00000144039
si:ch73-196i15.5
si:ch73-196i15.5
chr4_+_76735113 0.15 ENSDART00000075602
ms4a17a.6
membrane-spanning 4-domains, subfamily A, member 17A.6
chr18_+_37219140 0.15 ENSDART00000088247
qpctla
glutaminyl-peptide cyclotransferase-like a
chr14_+_15257658 0.15 ENSDART00000161625
ENSDART00000193577
si:dkey-77g12.4
si:dkey-203a12.5
si:dkey-77g12.4
si:dkey-203a12.5
chr22_-_16180467 0.15 ENSDART00000171331
ENSDART00000185607
vcam1b
vascular cell adhesion molecule 1b
chr18_-_3166726 0.14 ENSDART00000165002
aqp11
aquaporin 11
chr21_-_27338639 0.14 ENSDART00000130632
hif1al2
hypoxia-inducible factor 1, alpha subunit, like 2
chr22_-_372723 0.14 ENSDART00000112895
FNDC10
si:zfos-1324h11.5
chr19_+_10587307 0.14 ENSDART00000131225
si:dkey-211g8.4
si:dkey-211g8.4
chr20_+_53521648 0.14 ENSDART00000139794
pak6b
p21 protein (Cdc42/Rac)-activated kinase 6b
chr14_+_6159356 0.14 ENSDART00000157730
bscl2l
Bernardinelli-Seip congenital lipodystrophy 2, like
chr3_+_1219344 0.13 ENSDART00000161945
rrp7a
ribosomal RNA processing 7 homolog A
chr3_-_44059902 0.13 ENSDART00000158485
ENSDART00000159088
ENSDART00000165628
il4r.1
interleukin 4 receptor, tandem duplicate 1
chr4_+_47257854 0.13 ENSDART00000173868
crestin
crestin
chr10_-_20105553 0.13 ENSDART00000184502
pbdc1
polysaccharide biosynthesis domain containing 1
chr22_-_12890921 0.13 ENSDART00000146484
nab1a
NGFI-A binding protein 1a (EGR1 binding protein 1)
chr3_-_40933415 0.13 ENSDART00000055201
foxk1
forkhead box K1
chr5_+_32009956 0.13 ENSDART00000188482
scai
suppressor of cancer cell invasion
chr21_-_21781158 0.13 ENSDART00000113734
chrdl2
chordin-like 2
chr3_-_6709938 0.13 ENSDART00000172196
atg4db
autophagy related 4D, cysteine peptidase b
chr9_-_23922011 0.13 ENSDART00000145734
col6a3
collagen, type VI, alpha 3
chr11_-_762721 0.13 ENSDART00000166465
syn2b
synapsin IIb
chr7_+_25053331 0.13 ENSDART00000173998
si:dkey-23i12.7
si:dkey-23i12.7
chr24_-_27461295 0.12 ENSDART00000110748
ccl34b.9
chemokine (C-C motif) ligand 34b, duplicate 9
chr5_+_24179307 0.12 ENSDART00000051552
mpdu1a
mannose-P-dolichol utilization defect 1a
chr1_-_9195629 0.12 ENSDART00000143587
ENSDART00000192174
ern2
endoplasmic reticulum to nucleus signaling 2
chr24_-_39858710 0.12 ENSDART00000134251
slc12a7b
solute carrier family 12 (potassium/chloride transporter), member 7b
chr16_-_31717851 0.12 ENSDART00000169109
rbp5
retinol binding protein 1a, cellular
chr20_-_39273987 0.12 ENSDART00000127173
clu
clusterin
chr24_+_37406535 0.12 ENSDART00000138264
si:ch211-183d21.1
si:ch211-183d21.1
chr17_-_31308658 0.12 ENSDART00000124505
bahd1
bromo adjacent homology domain containing 1
chr24_-_26485098 0.12 ENSDART00000135496
ENSDART00000009609
ENSDART00000133782
ENSDART00000141029
ENSDART00000113739
eif5a
eukaryotic translation initiation factor 5A
chr7_-_28696556 0.12 ENSDART00000148822
adgrg1
adhesion G protein-coupled receptor G1
chr22_+_1462177 0.12 ENSDART00000164685
si:dkeyp-53d3.5
si:dkeyp-53d3.5
chr7_+_41313568 0.11 ENSDART00000016660
zgc:165532
zgc:165532
chr6_+_11989537 0.11 ENSDART00000190817
baz2ba
bromodomain adjacent to zinc finger domain, 2Ba
chr3_-_44012748 0.11 ENSDART00000167248
ENSDART00000157463
ENSDART00000159111
il4r.1
interleukin 4 receptor, tandem duplicate 1
chr18_-_16801033 0.11 ENSDART00000100100
admb
adrenomedullin b
chr18_-_14860435 0.11 ENSDART00000018502
mapk12a
mitogen-activated protein kinase 12a
chr12_+_17042754 0.11 ENSDART00000066439
ch25h
cholesterol 25-hydroxylase
chr2_+_4402765 0.11 ENSDART00000159525
bambib
BMP and activin membrane-bound inhibitor homolog (Xenopus laevis) b
chr13_-_50366950 0.11 ENSDART00000098209
sirt1
sirtuin 1
chr18_-_28938912 0.11 ENSDART00000136201
si:ch211-174j14.2
si:ch211-174j14.2
chr22_+_3238474 0.11 ENSDART00000157954
si:ch1073-178p5.3
si:ch1073-178p5.3
chr24_-_33291784 0.10 ENSDART00000124938
si:ch1073-406l10.2
si:ch1073-406l10.2
chr16_-_19254323 0.10 ENSDART00000138744
dnah11
dynein, axonemal, heavy chain 11
chr5_-_40734045 0.10 ENSDART00000010896
isl1
ISL LIM homeobox 1
chr16_-_29458806 0.10 ENSDART00000047931
lingo4b
leucine rich repeat and Ig domain containing 4b
chr21_+_19925910 0.10 ENSDART00000111694
ENSDART00000132653
tnksa
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase a
chr19_+_7759354 0.10 ENSDART00000151400
ubap2l
ubiquitin associated protein 2-like
chr20_+_32497260 0.10 ENSDART00000145175
ENSDART00000132921
si:ch73-257c13.2
si:ch73-257c13.2
chr24_-_26383978 0.10 ENSDART00000031426
skilb
SKI-like proto-oncogene b
chr9_+_13985567 0.10 ENSDART00000102296
cd28
CD28 molecule
chr14_+_6159162 0.10 ENSDART00000128638
bscl2l
Bernardinelli-Seip congenital lipodystrophy 2, like
chr6_-_35106425 0.10 ENSDART00000165139
nos1apa
nitric oxide synthase 1 (neuronal) adaptor protein a
chr14_-_49859747 0.10 ENSDART00000169456
ENSDART00000164967
nfkb1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr14_+_7452302 0.10 ENSDART00000130388
gfra3
GDNF family receptor alpha 3
chr24_+_13635108 0.10 ENSDART00000183008
trpa1b
transient receptor potential cation channel, subfamily A, member 1b
chr1_+_51827046 0.09 ENSDART00000052992
dand5
DAN domain family, member 5
chr19_-_26863626 0.09 ENSDART00000145568
prrt1
proline-rich transmembrane protein 1
chr5_-_49012569 0.09 ENSDART00000184690
si:dkey-172m14.2
si:dkey-172m14.2
chr15_+_23550890 0.09 ENSDART00000009796
ENSDART00000152720
MARK4
si:dkey-31m14.7
chr2_+_21063660 0.09 ENSDART00000022765
riok1
RIO kinase 1 (yeast)
chr21_-_4695583 0.09 ENSDART00000031425
zgc:55582
zgc:55582
chr16_-_1502699 0.09 ENSDART00000187189
sim1a
single-minded family bHLH transcription factor 1a
chr24_+_13635387 0.09 ENSDART00000105997
trpa1b
transient receptor potential cation channel, subfamily A, member 1b
chr16_-_31718013 0.09 ENSDART00000190716
rbp5
retinol binding protein 1a, cellular
chr20_+_25552057 0.09 ENSDART00000102913
cyp2v1
cytochrome P450, family 2, subfamily V, polypeptide 1
chr3_-_32170850 0.09 ENSDART00000055307
ENSDART00000157366
tnnt1
troponin T type 1 (skeletal, slow)
chr4_+_76637548 0.08 ENSDART00000133799
ms4a17a.9
membrane-spanning 4-domains, subfamily A, member 17A.9
chr24_-_37877743 0.08 ENSDART00000105658
tmem204
transmembrane protein 204
chr9_+_29585943 0.08 ENSDART00000185989
ENSDART00000115290
mcf2lb
mcf.2 cell line derived transforming sequence-like b
chr11_-_287670 0.08 ENSDART00000035737
slc11a2
solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
chr8_+_52491436 0.08 ENSDART00000164298
si:ch1073-392o20.1
si:ch1073-392o20.1
chr16_-_27749172 0.08 ENSDART00000145198
steap4
STEAP family member 4
chr17_-_23603263 0.08 ENSDART00000079559
ifit16
interferon-induced protein with tetratricopeptide repeats 16
chr6_+_40573365 0.08 ENSDART00000004075
uqcc2
ubiquinol-cytochrome c reductase complex assembly factor 2
chr21_-_34844059 0.08 ENSDART00000136402
zgc:56585
zgc:56585
chr1_-_10647484 0.08 ENSDART00000164541
ENSDART00000188958
ENSDART00000190904
si:dkey-31e10.1
si:dkey-31e10.1
chr11_+_11200550 0.08 ENSDART00000181339
ENSDART00000187116
myom2a
myomesin 2a
chr3_-_16039619 0.08 ENSDART00000143324
spsb3a
splA/ryanodine receptor domain and SOCS box containing 3a
chr25_-_28587896 0.08 ENSDART00000111908
si:dkeyp-67e1.6
si:dkeyp-67e1.6
chr19_+_8973042 0.07 ENSDART00000039597
crabp2b
cellular retinoic acid binding protein 2, b
chr7_+_58686860 0.07 ENSDART00000052332
penkb
proenkephalin b
chr5_-_42883761 0.07 ENSDART00000167374
BX323596.2

chr2_-_37837056 0.07 ENSDART00000158179
ENSDART00000160317
ENSDART00000171409
mettl17
methyltransferase like 17
chr4_+_29206813 0.07 ENSDART00000131893
si:dkey-23a23.1
si:dkey-23a23.1
chr10_+_22134606 0.07 ENSDART00000155228
si:dkey-4c2.11
si:dkey-4c2.11
chr7_+_48319916 0.07 ENSDART00000052122
crabp1b
cellular retinoic acid binding protein 1b
chr11_-_29996344 0.07 ENSDART00000003712
ENSDART00000126110
ace2
angiotensin I converting enzyme 2
chr9_-_23922778 0.07 ENSDART00000135769
col6a3
collagen, type VI, alpha 3
chr16_+_32059785 0.07 ENSDART00000134459
si:dkey-40m6.8
si:dkey-40m6.8
chr13_-_37631092 0.07 ENSDART00000108855
si:dkey-188i13.7
si:dkey-188i13.7
chr21_+_40443118 0.07 ENSDART00000190675
ssh2b
slingshot protein phosphatase 2b
chr21_+_20901505 0.06 ENSDART00000132741
c7b
complement component 7b
chr17_+_53292215 0.06 ENSDART00000170686
si:ch1073-416d2.3
si:ch1073-416d2.3
chr19_+_34311374 0.06 ENSDART00000086617
gabbr2
gamma-aminobutyric acid (GABA) B receptor, 2
chr7_+_27277236 0.06 ENSDART00000185161
sox6
SRY (sex determining region Y)-box 6
chr2_+_10766744 0.06 ENSDART00000015379
gfi1aa
growth factor independent 1A transcription repressor a
chr18_-_44888375 0.06 ENSDART00000160506
si:ch211-71n6.4
si:ch211-71n6.4
chr18_+_10820430 0.06 ENSDART00000161990
mical3a
microtubule associated monooxygenase, calponin and LIM domain containing 3a
chr6_+_55357188 0.06 ENSDART00000158219
pltp
phospholipid transfer protein
chr9_-_54304684 0.06 ENSDART00000109512
il13
interleukin 13
chr23_-_5101847 0.06 ENSDART00000122240
etv7
ets variant 7
chr20_-_25412181 0.06 ENSDART00000062780
itsn2a
intersectin 2a
chr16_+_25809235 0.06 ENSDART00000181196
irgq1
immunity-related GTPase family, q1
chr2_-_37837472 0.06 ENSDART00000165347
mettl17
methyltransferase like 17

Network of associatons between targets according to the STRING database.

First level regulatory network of stat3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:1990403 embryonic brain development(GO:1990403)
0.1 0.5 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.1 0.3 GO:0031642 negative regulation of myelination(GO:0031642) negative regulation of neurological system process(GO:0031645)
0.1 0.6 GO:0021888 hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888)
0.1 0.3 GO:2000471 regulation of hematopoietic stem cell migration(GO:2000471)
0.1 0.2 GO:0002532 production of molecular mediator involved in inflammatory response(GO:0002532)
0.1 0.2 GO:0050968 chemosensory behavior(GO:0007635) detection of chemical stimulus involved in sensory perception of pain(GO:0050968)
0.0 0.2 GO:0007412 axon target recognition(GO:0007412)
0.0 0.2 GO:0060467 negative regulation of fertilization(GO:0060467) prevention of polyspermy(GO:0060468) cortical granule exocytosis(GO:0060471)
0.0 0.3 GO:0048681 negative regulation of axon regeneration(GO:0048681) negative regulation of neuron projection regeneration(GO:0070571)
0.0 0.1 GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186) peptidyl-glutamine modification(GO:0018199)
0.0 0.6 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.0 0.1 GO:0072020 proximal straight tubule development(GO:0072020)
0.0 0.2 GO:0034695 response to prostaglandin E(GO:0034695) cellular response to prostaglandin E stimulus(GO:0071380)
0.0 0.2 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.2 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.0 0.1 GO:0065001 specification of axis polarity(GO:0065001)
0.0 0.2 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.1 GO:0042546 cell wall biogenesis(GO:0042546) cell wall macromolecule biosynthetic process(GO:0044038) cellular component macromolecule biosynthetic process(GO:0070589)
0.0 0.1 GO:2001014 regulation of skeletal muscle cell differentiation(GO:2001014)
0.0 0.1 GO:1904353 positive regulation of telomere maintenance(GO:0032206) regulation of telomere capping(GO:1904353) positive regulation of telomere capping(GO:1904355)
0.0 0.1 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.0 0.5 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.0 0.1 GO:0034375 high-density lipoprotein particle remodeling(GO:0034375)
0.0 0.1 GO:0015677 copper ion import(GO:0015677)
0.0 0.1 GO:0070445 regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.0 0.1 GO:0051561 positive regulation of mitochondrial calcium ion concentration(GO:0051561)
0.0 0.1 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.0 0.2 GO:0006798 polyphosphate metabolic process(GO:0006797) polyphosphate catabolic process(GO:0006798)
0.0 0.1 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.1 GO:0002839 response to tumor cell(GO:0002347) natural killer cell cytokine production(GO:0002370) immune response to tumor cell(GO:0002418) natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of natural killer cell cytokine production(GO:0002727) positive regulation of natural killer cell cytokine production(GO:0002729) positive regulation of response to biotic stimulus(GO:0002833) regulation of response to tumor cell(GO:0002834) positive regulation of response to tumor cell(GO:0002836) regulation of immune response to tumor cell(GO:0002837) positive regulation of immune response to tumor cell(GO:0002839) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860) positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
0.0 0.2 GO:0048319 axial mesoderm morphogenesis(GO:0048319)
0.0 0.0 GO:0033005 positive regulation of mast cell activation(GO:0033005)
0.0 0.1 GO:0045901 positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.0 0.2 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)
0.0 0.0 GO:0035751 regulation of lysosomal lumen pH(GO:0035751)
0.0 0.3 GO:0030316 osteoclast differentiation(GO:0030316)
0.0 0.2 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.0 0.1 GO:0034653 diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.0 0.2 GO:0002831 regulation of response to biotic stimulus(GO:0002831) regulation of defense response to virus(GO:0050688)
0.0 0.4 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 0.1 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.0 0.0 GO:0002792 negative regulation of peptide secretion(GO:0002792) negative regulation of peptide hormone secretion(GO:0090278)
0.0 0.4 GO:0032482 Rab protein signal transduction(GO:0032482)
0.0 0.2 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.6 GO:0035082 axoneme assembly(GO:0035082)
0.0 0.0 GO:1990575 mitochondrial ornithine transport(GO:0000066) mitochondrial L-ornithine transmembrane transport(GO:1990575)
0.0 0.2 GO:0043248 proteasome assembly(GO:0043248)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.7 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.1 0.2 GO:0033268 node of Ranvier(GO:0033268)
0.0 0.1 GO:0034456 CURI complex(GO:0032545) UTP-C complex(GO:0034456)
0.0 0.1 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0 0.2 GO:0030897 HOPS complex(GO:0030897)
0.0 0.6 GO:0001518 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 0.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 1.0 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.1 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 0.2 GO:0042583 chromaffin granule(GO:0042583)
0.0 0.1 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.2 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.2 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.3 GO:0016282 eukaryotic 43S preinitiation complex(GO:0016282)
0.0 0.3 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.2 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.5 GO:0022626 cytosolic ribosome(GO:0022626)
0.0 0.4 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0070738 protein-glycine ligase activity(GO:0070735) tubulin-glycine ligase activity(GO:0070738)
0.1 0.4 GO:0000035 acyl binding(GO:0000035)
0.1 0.4 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.1 0.6 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.1 0.3 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 0.3 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.6 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.3 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.1 GO:0016603 glutaminyl-peptide cyclotransferase activity(GO:0016603)
0.0 0.2 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.1 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086)
0.0 0.3 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.2 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.2 GO:0016918 retinal binding(GO:0016918)
0.0 0.1 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.2 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.2 GO:0004309 exopolyphosphatase activity(GO:0004309)
0.0 0.1 GO:0005252 open rectifier potassium channel activity(GO:0005252)
0.0 0.2 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.1 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.3 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.1 GO:0000254 C-4 methylsterol oxidase activity(GO:0000254)
0.0 0.1 GO:1904121 phosphatidylethanolamine transporter activity(GO:1904121)
0.0 0.4 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0 0.1 GO:0010858 calcium-dependent protein kinase inhibitor activity(GO:0008427) calcium-dependent protein kinase regulator activity(GO:0010858)
0.0 0.2 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.5 GO:0019843 rRNA binding(GO:0019843)
0.0 0.1 GO:0031769 glucagon receptor binding(GO:0031769)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.2 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.2 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.1 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.2 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.2 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.1 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 1.5 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.3 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.1 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS Genes involved in Synthesis of bile acids and bile salts