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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for stat4

Z-value: 0.60

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Transcription factors associated with stat4

Gene Symbol Gene ID Gene Info
stat4
ENSDARG00000028731 signal transducer and activator of transcription 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
stat4dr11_v1_chr9_+_41156287_41156287-0.272.8e-01Click!

Activity profile of stat4 motif

Sorted Z-values of stat4 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_21005725 2.24 ENSDART00000041370
cx44.2
connexin 44.2
chr21_+_25777425 2.19 ENSDART00000021620
cldnd
claudin d
chr9_+_44994214 1.57 ENSDART00000141434
retsatl
retinol saturase (all-trans-retinol 13,14-reductase) like
chr6_+_41503854 1.51 ENSDART00000136538
ENSDART00000140108
ENSDART00000084861
cish
cytokine inducible SH2-containing protein
chr15_+_25489406 1.49 ENSDART00000162482
zgc:152863
zgc:152863
chr17_+_30591287 1.41 ENSDART00000154243
si:dkey-190l8.2
si:dkey-190l8.2
chr7_-_26518086 1.28 ENSDART00000058913
eif4a1a
eukaryotic translation initiation factor 4A1A
chr8_-_25033681 1.23 ENSDART00000003493
nfyal
nuclear transcription factor Y, alpha, like
chr1_-_38171648 1.22 ENSDART00000137451
ENSDART00000047159
hmgb2a
high mobility group box 2a
chr3_-_31879201 1.21 ENSDART00000076189
zgc:171779
zgc:171779
chr21_-_32060993 1.18 ENSDART00000131651
si:ch211-160j14.2
si:ch211-160j14.2
chr1_-_6085750 1.16 ENSDART00000138891
si:ch1073-345a8.1
si:ch1073-345a8.1
chr17_-_12498096 1.15 ENSDART00000149551
ENSDART00000105215
ENSDART00000191207
emilin1b
elastin microfibril interfacer 1b
chr5_-_57624425 1.11 ENSDART00000167892
zgc:193711
zgc:193711
chr15_+_20529197 1.07 ENSDART00000060935
ENSDART00000137926
ENSDART00000140087
tnfaip1
tumor necrosis factor, alpha-induced protein 1 (endothelial)
chr21_+_39100289 1.03 ENSDART00000075958
slc13a2
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
chr9_-_55946377 1.02 ENSDART00000161536
ENSDART00000169432
SH3RF3
si:ch211-124n19.2
chr14_-_33278084 1.01 ENSDART00000132850
stard14
START domain containing 14
chr18_-_3527988 1.00 ENSDART00000157669
capn5a
calpain 5a
chr1_-_36770883 0.99 ENSDART00000167831
prmt9
protein arginine methyltransferase 9
chr7_+_32693890 0.98 ENSDART00000121972
slc39a13
solute carrier family 39 (zinc transporter), member 13
chr3_+_36646054 0.98 ENSDART00000170013
ENSDART00000159948
gspt1l
G1 to S phase transition 1, like
chr18_-_3527686 0.97 ENSDART00000169049
capn5a
calpain 5a
chr18_-_20444296 0.96 ENSDART00000132993
kif23
kinesin family member 23
chr7_-_50764714 0.93 ENSDART00000110283
iqgap1
IQ motif containing GTPase activating protein 1
chr10_+_29770120 0.92 ENSDART00000100032
ENSDART00000193205
hyou1
hypoxia up-regulated 1
chr6_-_8377055 0.90 ENSDART00000131513
ilf3a
interleukin enhancer binding factor 3a
chr1_+_12177195 0.87 ENSDART00000146842
ENSDART00000142081
stra6l
STRA6-like
chr19_+_43885770 0.87 ENSDART00000135599
lypla2
lysophospholipase II
chr12_+_28888975 0.85 ENSDART00000076362
phkg2
phosphorylase kinase, gamma 2 (testis)
chr4_+_16827390 0.83 ENSDART00000113344
kiss2
kisspeptin 2
chr25_-_36263115 0.83 ENSDART00000143046
ENSDART00000139002
dus2
dihydrouridine synthase 2
chr12_-_37299646 0.81 ENSDART00000146142
ENSDART00000085201
pmp22b
peripheral myelin protein 22b
chr7_-_26497947 0.81 ENSDART00000058910
sox19b
SRY (sex determining region Y)-box 19b
chr24_-_26820698 0.81 ENSDART00000147788
fndc3bb
fibronectin type III domain containing 3Bb
chr3_-_3439150 0.79 ENSDART00000021286
A2ML1 (1 of many)
si:dkey-46g23.5
chr7_+_45963767 0.79 ENSDART00000163098
pop4
POP4 homolog, ribonuclease P/MRP subunit
chr1_-_24458057 0.78 ENSDART00000140197
ENSDART00000181286
sh3d19
SH3 domain containing 19
chr12_-_35393211 0.72 ENSDART00000137139
camk2g1
calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma 1
chr6_-_11800427 0.70 ENSDART00000126243
march7
membrane-associated ring finger (C3HC4) 7
chr5_+_67835595 0.69 ENSDART00000159386
si:ch211-271b14.1
si:ch211-271b14.1
chr7_+_34487833 0.69 ENSDART00000173854
cln6a
CLN6, transmembrane ER protein a
chr23_-_33558161 0.68 ENSDART00000018301
itga5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr22_-_11078988 0.68 ENSDART00000126664
ENSDART00000006927
use1
unconventional SNARE in the ER 1 homolog (S. cerevisiae)
chr19_+_38168006 0.68 ENSDART00000087662
ENSDART00000177759
phf14
PHD finger protein 14
chr2_+_2957515 0.67 ENSDART00000160715
pik3r3a
phosphoinositide-3-kinase, regulatory subunit 3a (gamma)
chr23_+_4350897 0.67 ENSDART00000190593
mybl2a
v-myb avian myeloblastosis viral oncogene homolog-like 2a
chr19_+_1673599 0.66 ENSDART00000163127
klhl7
kelch-like family member 7
chr14_+_28473173 0.66 ENSDART00000017075
xiap
X-linked inhibitor of apoptosis
chr19_-_3821678 0.64 ENSDART00000169639
si:dkey-206d17.12
si:dkey-206d17.12
chr16_+_16266428 0.63 ENSDART00000188433
setd2
SET domain containing 2
chr16_-_2390931 0.62 ENSDART00000149463
hace1
HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1
chr22_-_11493236 0.61 ENSDART00000002691
tspan7b
tetraspanin 7b
chr19_-_46091497 0.61 ENSDART00000178772
ENSDART00000167255
ptdss1b
si:dkey-108k24.2
phosphatidylserine synthase 1b
si:dkey-108k24.2
chr23_+_29966466 0.61 ENSDART00000143583
dvl1a
dishevelled segment polarity protein 1a
chr13_-_9300299 0.59 ENSDART00000144142
HTRA2 (1 of many)
si:dkey-33c12.12
chr16_-_22585289 0.58 ENSDART00000134239
ENSDART00000193959
ENSDART00000077998
si:dkey-238m4.3
cgna
si:dkey-238m4.3
cingulin a
chr19_-_43750389 0.58 ENSDART00000147328
ppt1
palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile)
chr7_+_38770167 0.57 ENSDART00000190827
arhgap1
Rho GTPase activating protein 1
chr11_+_19603251 0.56 ENSDART00000005639
thoc7
THO complex 7
chr16_-_9830451 0.55 ENSDART00000148528
grhl2a
grainyhead-like transcription factor 2a
chr7_+_29065915 0.54 ENSDART00000136657
vrk3
vaccinia related kinase 3
chr9_-_27738110 0.54 ENSDART00000060347
crygs2
crystallin, gamma S2
chr6_+_2195625 0.52 ENSDART00000155659
acvr1bb
activin A receptor type 1Bb
chr14_-_32631519 0.52 ENSDART00000167282
ENSDART00000052938
atp11c
ATPase phospholipid transporting 11C
chr7_-_24875421 0.52 ENSDART00000173920
adad2
adenosine deaminase domain containing 2
chr20_-_30938184 0.52 ENSDART00000147359
ENSDART00000062552
wtap
WT1 associated protein
chr22_+_20172018 0.52 ENSDART00000188104
hmg20b
high mobility group 20B
chr2_+_16449627 0.51 ENSDART00000005381
zgc:110269
zgc:110269
chr12_+_33403694 0.51 ENSDART00000124083
fasn
fatty acid synthase
chr23_+_43718115 0.51 ENSDART00000149266
ENSDART00000149503
anapc10
anaphase promoting complex subunit 10
chr13_+_8255106 0.50 ENSDART00000080465
hells
helicase, lymphoid specific
chr21_+_20488662 0.49 ENSDART00000147951
efna5a
ephrin-A5a
chr15_-_23721618 0.49 ENSDART00000109318
zc3h4
zinc finger CCCH-type containing 4
chr5_-_37959874 0.47 ENSDART00000031719
mpzl2b
myelin protein zero-like 2b
chr5_+_36768674 0.47 ENSDART00000146854
mark4a
MAP/microtubule affinity-regulating kinase 4a
chr10_+_8401929 0.47 ENSDART00000059028
hvcn1
hydrogen voltage-gated channel 1
chr3_-_32275975 0.47 ENSDART00000178448
cpt1cb
carnitine palmitoyltransferase 1Cb
chr1_-_493218 0.47 ENSDART00000031635
ercc5
excision repair cross-complementation group 5
chr21_-_11970199 0.44 ENSDART00000114524
nop56
NOP56 ribonucleoprotein homolog
chr21_-_40049642 0.43 ENSDART00000124416
med31
mediator complex subunit 31
chr7_-_29043075 0.43 ENSDART00000052342
thap11
THAP domain containing 11
chr8_-_18203274 0.43 ENSDART00000134078
ENSDART00000180235
ENSDART00000080006
ENSDART00000125418
ENSDART00000142114
elovl8b
ELOVL fatty acid elongase 8b
chr3_+_40289418 0.43 ENSDART00000017304
cpsf4
cleavage and polyadenylation specific factor 4
chr5_-_41984298 0.43 ENSDART00000189535
ncor1
nuclear receptor corepressor 1
chr2_-_9989919 0.42 ENSDART00000180213
ENSDART00000184369
imp3
IMP3, U3 small nucleolar ribonucleoprotein, homolog (yeast)
chr6_+_29386728 0.42 ENSDART00000104303
actl6a
actin-like 6A
chr25_+_16312258 0.42 ENSDART00000064187
parvaa
parvin, alpha a
chr5_+_54280135 0.42 ENSDART00000170218
ENSDART00000166050
rangrf
RAN guanine nucleotide release factor
chr6_-_3998199 0.42 ENSDART00000059212
unc50
unc-50 homolog (C. elegans)
chr12_+_36109507 0.42 ENSDART00000175409
map2k6
mitogen-activated protein kinase kinase 6
chr9_+_38502524 0.41 ENSDART00000087229
lmln
leishmanolysin-like (metallopeptidase M8 family)
chr23_+_1216215 0.41 ENSDART00000165957
utrn
utrophin
chr13_-_36049008 0.40 ENSDART00000189978
lgmn
legumain
chr21_+_20901505 0.40 ENSDART00000132741
c7b
complement component 7b
chr2_+_42005217 0.40 ENSDART00000143562
gbp2
guanylate binding protein 2
chr21_-_3613702 0.40 ENSDART00000139194
dym
dymeclin
chr18_+_7543347 0.39 ENSDART00000103467
arf5
ADP-ribosylation factor 5
chr8_-_18203092 0.38 ENSDART00000140620
elovl8b
ELOVL fatty acid elongase 8b
chr25_+_32390794 0.38 ENSDART00000012600
galk2
galactokinase 2
chr23_-_5783421 0.36 ENSDART00000131521
ENSDART00000019455
csrp1a
cysteine and glycine-rich protein 1a
chr25_+_11281970 0.35 ENSDART00000180094
AKAP13
si:dkey-187e18.1
chr22_-_20838011 0.35 ENSDART00000186056
dot1l
DOT1-like histone H3K79 methyltransferase
chr14_-_22015232 0.35 ENSDART00000137795
ssrp1a
structure specific recognition protein 1a
chr6_+_4387150 0.35 ENSDART00000181283
rbm26
RNA binding motif protein 26
chr23_-_43718067 0.34 ENSDART00000015777
abce1
ATP-binding cassette, sub-family E (OABP), member 1
chr3_-_61377127 0.34 ENSDART00000155932
si:dkey-111k8.2
si:dkey-111k8.2
chr19_-_12315693 0.34 ENSDART00000151158
ncaldb
neurocalcin delta b
chr22_-_28645676 0.33 ENSDART00000005883
jagn1b
jagunal homolog 1b
chr3_-_13599482 0.33 ENSDART00000166639
tufm
Tu translation elongation factor, mitochondrial
chr21_+_39197628 0.33 ENSDART00000113607
cpdb
carboxypeptidase D, b
chr23_-_17451264 0.32 ENSDART00000190748
tpd52l2b
tumor protein D52-like 2b
chr16_-_4610255 0.32 ENSDART00000081852
ENSDART00000123253
ENSDART00000127554
ENSDART00000029485
arnt
aryl hydrocarbon receptor nuclear translocator
chr22_-_20514043 0.32 ENSDART00000088890
atp8b3
ATPase phospholipid transporting 8B3
chr3_-_43954971 0.32 ENSDART00000167159
ENSDART00000189315
ubfd1
ubiquitin family domain containing 1
chr2_+_42005475 0.32 ENSDART00000056461
gbp2
guanylate binding protein 2
chr6_-_30689126 0.31 ENSDART00000065211
pars2
prolyl-tRNA synthetase 2, mitochondrial
chr8_+_47897734 0.31 ENSDART00000140266
mfn2
mitofusin 2
chr18_-_21047580 0.31 ENSDART00000010189
igf1ra
insulin-like growth factor 1a receptor
chr5_+_36895545 0.30 ENSDART00000135776
ENSDART00000147561
ENSDART00000133842
ENSDART00000051185
ENSDART00000141984
ENSDART00000136301
ENSDART00000142388
srsf7a
serine/arginine-rich splicing factor 7a
chr19_+_40379771 0.30 ENSDART00000017917
ENSDART00000110699
vps50
vps50
VPS50 EARP/GARPII complex subunit
VPS50 EARP/GARPII complex subunit
chr24_+_37484661 0.30 ENSDART00000165125
ENSDART00000109221
wdr90
WD repeat domain 90
chr10_-_34033680 0.30 ENSDART00000180734
rfc3
replication factor C (activator 1) 3
chr2_-_16449504 0.29 ENSDART00000144801
atr
ATR serine/threonine kinase
chr1_-_18585046 0.29 ENSDART00000147228
fam114a1
family with sequence similarity 114, member A1
chr8_-_11067079 0.29 ENSDART00000181986
dennd2c
DENN/MADD domain containing 2C
chr22_-_9861531 0.29 ENSDART00000193197
si:dkey-253d23.2
si:dkey-253d23.2
chr8_-_20838342 0.28 ENSDART00000141345
si:ch211-133l5.7
si:ch211-133l5.7
chr12_+_23371542 0.28 ENSDART00000078896
waca
WW domain containing adaptor with coiled-coil a
chr11_+_5681762 0.27 ENSDART00000179139
arid3a
AT rich interactive domain 3A (BRIGHT-like)
chr11_+_41459408 0.27 ENSDART00000182285
park7
parkinson protein 7
chr12_-_26383242 0.26 ENSDART00000152941
usp54b
ubiquitin specific peptidase 54b
chr7_-_34434889 0.25 ENSDART00000159982
nr1h3
nuclear receptor subfamily 1, group H, member 3
chr2_+_37838259 0.25 ENSDART00000136796
parp2
poly (ADP-ribose) polymerase 2
chr22_-_22130623 0.25 ENSDART00000113168
CU855878.1

chr16_+_45746549 0.25 ENSDART00000190403
paqr6
progestin and adipoQ receptor family member VI
chr14_-_45595711 0.24 ENSDART00000074038
scyl1
SCY1-like, kinase-like 1
chr23_-_31763753 0.24 ENSDART00000053399
aldh8a1
aldehyde dehydrogenase 8 family, member A1
chr14_+_36521005 0.24 ENSDART00000192286
TENM3
si:dkey-237h12.3
chr17_+_24111392 0.23 ENSDART00000180123
ENSDART00000182787
ENSDART00000189752
ENSDART00000184940
ENSDART00000185363
ENSDART00000064067
ehbp1
EH domain binding protein 1
chr15_-_26538989 0.23 ENSDART00000032880
rpa1
replication protein A1
chr19_-_22843480 0.23 ENSDART00000052503
nudcd1
NudC domain containing 1
chr15_-_31508221 0.22 ENSDART00000121464
si:dkey-1m11.5
si:dkey-1m11.5
chr24_-_20599781 0.22 ENSDART00000179664
ENSDART00000141823
zbtb47b
zinc finger and BTB domain containing 47b
chr19_-_10286228 0.22 ENSDART00000027316
cnot3b
CCR4-NOT transcription complex, subunit 3b
chr8_+_54055390 0.21 ENSDART00000102696
magi1a
membrane associated guanylate kinase, WW and PDZ domain containing 1a
chr5_+_36895860 0.20 ENSDART00000134493
srsf7a
serine/arginine-rich splicing factor 7a
chr11_+_43401201 0.20 ENSDART00000190128
vipb
vasoactive intestinal peptide b
chr20_-_28433616 0.20 ENSDART00000169289
wdr21
WD repeat domain 21
chr14_-_52433292 0.20 ENSDART00000164272
rest
RE1-silencing transcription factor
chr19_-_17658160 0.20 ENSDART00000151766
ENSDART00000170790
ENSDART00000186678
ENSDART00000188045
ENSDART00000176980
ENSDART00000166313
ENSDART00000188589
thrb
thyroid hormone receptor beta
chr23_-_25779995 0.20 ENSDART00000110670
si:dkey-21c19.3
si:dkey-21c19.3
chr17_+_12767640 0.20 ENSDART00000112469
ENSDART00000154984
ENSDART00000124584
ENSDART00000193647
ENSDART00000179686
ralgapa1
Ral GTPase activating protein, alpha subunit 1 (catalytic)
chr1_-_28831848 0.18 ENSDART00000148536
GK3P
zgc:172295
chr9_-_16062938 0.18 ENSDART00000099479
crfb4
cytokine receptor family member b4
chr4_-_1818315 0.18 ENSDART00000067433
ube2nb
ubiquitin-conjugating enzyme E2Nb
chr23_-_24483311 0.18 ENSDART00000185793
ENSDART00000109248
spen
spen family transcriptional repressor
chr19_-_2317558 0.17 ENSDART00000190300
sp8a
sp8 transcription factor a
chr6_+_18367388 0.17 ENSDART00000163394
dgke
diacylglycerol kinase, epsilon
chr2_+_25868404 0.17 ENSDART00000143517
ENSDART00000187743
slc7a14a
solute carrier family 7, member 14a
chr17_-_45040813 0.17 ENSDART00000075514
entpd5a
ectonucleoside triphosphate diphosphohydrolase 5a
chr14_+_45970033 0.16 ENSDART00000047716
fermt3b
fermitin family member 3b
chr18_+_17725410 0.16 ENSDART00000090608
rspry1
ring finger and SPRY domain containing 1
chr9_+_27354653 0.15 ENSDART00000134134
tlr20.2
toll-like receptor 20, tandem duplicate 2
chr17_+_32571584 0.15 ENSDART00000087565
eva1a
eva-1 homolog A (C. elegans)
chr17_-_8173380 0.15 ENSDART00000148520
syne1b
spectrin repeat containing, nuclear envelope 1b
chr19_+_7938121 0.14 ENSDART00000140053
ENSDART00000146649
si:dkey-266f7.5
si:dkey-266f7.5
chr11_-_11910225 0.14 ENSDART00000159922
si:ch211-69b7.6
si:ch211-69b7.6
chr1_+_37391716 0.14 ENSDART00000191986
sparcl1
SPARC-like 1
chr12_-_9796237 0.14 ENSDART00000149344
prdm9
PR domain containing 9
chr20_+_18994059 0.13 ENSDART00000152380
tdh
L-threonine dehydrogenase
chr10_+_20392083 0.13 ENSDART00000166867
r3hcc1
R3H domain and coiled-coil containing 1
chr15_-_31390985 0.13 ENSDART00000060117
or111-6
odorant receptor, family D, subfamily 111, member 6
chr6_+_18423402 0.12 ENSDART00000159747
rab11fip4b
RAB11 family interacting protein 4 (class II) b
chr5_-_40190949 0.12 ENSDART00000175588
wdfy3
WD repeat and FYVE domain containing 3
chr7_-_27696958 0.11 ENSDART00000173470
calca
calcitonin/calcitonin-related polypeptide, alpha
chr17_-_45386546 0.11 ENSDART00000182647
tmem206
transmembrane protein 206
chr10_-_36207737 0.11 ENSDART00000159366
or109-13
odorant receptor, family D, subfamily 109, member 13
chr13_+_12405051 0.11 ENSDART00000108543
atp10d
ATPase phospholipid transporting 10D
chr19_-_43750108 0.11 ENSDART00000171806
ppt1
palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile)
chr15_-_31390760 0.10 ENSDART00000190774
or111-6
odorant receptor, family D, subfamily 111, member 6
chr12_+_30367079 0.10 ENSDART00000190112
ccdc186
si:ch211-225b10.4
chr20_+_10166297 0.10 ENSDART00000141877
kcnk10a
potassium channel, subfamily K, member 10a
chr16_+_38394371 0.10 ENSDART00000137954
cd83
CD83 molecule
chr17_-_2834764 0.10 ENSDART00000024027
bdkrb1
bradykinin receptor B1
chr11_-_11882982 0.10 ENSDART00000190853
wipf2a
WAS/WASL interacting protein family, member 2a
chr4_-_13518381 0.10 ENSDART00000067153
ifng1-1
interferon, gamma 1-1
chr11_+_6431133 0.10 ENSDART00000190742
FO904935.1

chr21_+_1378250 0.10 ENSDART00000186912
TCF4
transcription factor 4
chr20_-_43775495 0.10 ENSDART00000100610
ENSDART00000149001
ENSDART00000148809
ENSDART00000100608
matn3a
matrilin 3a
chr3_+_3852614 0.09 ENSDART00000184334
ENSDART00000162313
si:ch73-338o16.4
si:ch73-338o16.4
chr24_+_18299506 0.09 ENSDART00000172056
tpk1
thiamin pyrophosphokinase 1
chr16_-_11859309 0.09 ENSDART00000145754
cxcr3.1
chemokine (C-X-C motif) receptor 3, tandem duplicate 1
chr21_+_39197418 0.09 ENSDART00000076000
cpdb
carboxypeptidase D, b
chr15_-_5245726 0.09 ENSDART00000174079
ENSDART00000174041
or128-1
odorant receptor, family E, subfamily 128, member 1
chr1_-_53407087 0.09 ENSDART00000157910
elmod2
ELMO/CED-12 domain containing 2
chr12_-_17602958 0.09 ENSDART00000134690
ENSDART00000028090
eif2ak1
eukaryotic translation initiation factor 2-alpha kinase 1
chr16_-_10071886 0.08 ENSDART00000136168
ENSDART00000130382
ptpn2a
protein tyrosine phosphatase, non-receptor type 2, a
chr3_+_58119571 0.08 ENSDART00000108979
si:ch211-256e16.4
si:ch211-256e16.4
chr3_-_31057624 0.08 ENSDART00000152901
armc5
armadillo repeat containing 5

Network of associatons between targets according to the STRING database.

First level regulatory network of stat4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.2 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.3 1.5 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.3 0.9 GO:2000378 negative regulation of reactive oxygen species metabolic process(GO:2000378)
0.2 1.0 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.2 0.9 GO:0071938 vitamin A transport(GO:0071938) vitamin A import(GO:0071939)
0.2 0.6 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.2 0.5 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.1 1.0 GO:0040016 embryonic cleavage(GO:0040016)
0.1 0.8 GO:0097198 histone H3-K36 trimethylation(GO:0097198)
0.1 1.6 GO:0098734 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.1 0.7 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
0.1 0.3 GO:0038158 granulocyte colony-stimulating factor signaling pathway(GO:0038158)
0.1 0.3 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.1 0.4 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.1 0.3 GO:2000677 histone H3-K79 methylation(GO:0034729) regulation of transcription regulatory region DNA binding(GO:2000677)
0.1 0.5 GO:0080009 mRNA methylation(GO:0080009)
0.1 0.6 GO:0090177 establishment of planar polarity of embryonic epithelium(GO:0042249) establishment of planar polarity involved in neural tube closure(GO:0090177) regulation of establishment of planar polarity involved in neural tube closure(GO:0090178) planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.1 0.3 GO:1904729 regulation of intestinal absorption(GO:1904478) regulation of intestinal lipid absorption(GO:1904729)
0.1 1.1 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.1 0.5 GO:0048660 regulation of smooth muscle cell proliferation(GO:0048660) negative regulation of smooth muscle cell proliferation(GO:0048662)
0.1 0.2 GO:1903430 branchiomotor neuron axon guidance(GO:0021785) negative regulation of cell maturation(GO:1903430)
0.1 0.4 GO:0071294 cellular response to zinc ion(GO:0071294)
0.1 0.6 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.1 0.2 GO:0042182 ketone catabolic process(GO:0042182)
0.1 0.3 GO:1901207 regulation of heart looping(GO:1901207)
0.1 1.0 GO:0018216 peptidyl-arginine methylation(GO:0018216)
0.1 0.5 GO:0044030 regulation of DNA methylation(GO:0044030)
0.1 0.4 GO:0006012 galactose metabolic process(GO:0006012)
0.1 0.2 GO:0033632 cell-cell adhesion mediated by integrin(GO:0033631) regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.1 0.7 GO:0043551 regulation of lipid kinase activity(GO:0043550) regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.0 1.0 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.2 GO:0042671 retinal cone cell fate determination(GO:0042671) eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate determination(GO:0043703) retinal cone cell fate commitment(GO:0046551) photoreceptor cell fate commitment(GO:0046552) camera-type eye photoreceptor cell fate commitment(GO:0060220)
0.0 0.4 GO:0098789 mRNA cleavage involved in mRNA processing(GO:0098787) pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.5 GO:0006382 adenosine to inosine editing(GO:0006382)
0.0 0.3 GO:0044783 G1 DNA damage checkpoint(GO:0044783)
0.0 0.5 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.8 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 1.3 GO:0002183 cytoplasmic translational initiation(GO:0002183)
0.0 0.1 GO:0002468 dendritic cell antigen processing and presentation(GO:0002468)
0.0 0.1 GO:0009229 thiamine diphosphate biosynthetic process(GO:0009229)
0.0 0.2 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.0 0.9 GO:2001243 negative regulation of intrinsic apoptotic signaling pathway(GO:2001243)
0.0 0.2 GO:0006567 threonine metabolic process(GO:0006566) threonine catabolic process(GO:0006567)
0.0 0.8 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.4 GO:0097324 melanocyte migration(GO:0097324)
0.0 0.2 GO:2000036 regulation of stem cell population maintenance(GO:2000036)
0.0 0.3 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 0.3 GO:0048009 insulin-like growth factor receptor signaling pathway(GO:0048009)
0.0 0.1 GO:0031335 regulation of sulfur amino acid metabolic process(GO:0031335) regulation of homocysteine metabolic process(GO:0050666)
0.0 0.3 GO:0033753 ribosomal subunit export from nucleus(GO:0000054) ribosome localization(GO:0033750) establishment of ribosome localization(GO:0033753) rRNA-containing ribonucleoprotein complex export from nucleus(GO:0071428)
0.0 0.8 GO:0009950 dorsal/ventral axis specification(GO:0009950)
0.0 0.7 GO:0031398 positive regulation of protein ubiquitination(GO:0031398)
0.0 0.9 GO:0009250 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 0.1 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.0 0.5 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.6 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 0.7 GO:0072114 pronephros morphogenesis(GO:0072114)
0.0 0.7 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.1 GO:0050996 positive regulation of lipid catabolic process(GO:0050996)
0.0 0.6 GO:0006406 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0 0.4 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.0 0.2 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.4 GO:0043967 histone H4 acetylation(GO:0043967)
0.0 0.4 GO:0019835 cytolysis(GO:0019835)
0.0 0.1 GO:0003245 growth involved in heart morphogenesis(GO:0003241) cardiac chamber ballooning(GO:0003242) cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.0 0.1 GO:0018063 protein-heme linkage(GO:0017003) protein-tetrapyrrole linkage(GO:0017006) cytochrome c-heme linkage(GO:0018063)
0.0 0.2 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.5 GO:0032924 activin receptor signaling pathway(GO:0032924)
0.0 1.6 GO:0008033 tRNA processing(GO:0008033)
0.0 0.4 GO:0032456 endocytic recycling(GO:0032456)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.2 1.0 GO:0018444 translation release factor complex(GO:0018444)
0.2 0.5 GO:0031362 intrinsic component of external side of plasma membrane(GO:0031233) anchored component of external side of plasma membrane(GO:0031362)
0.1 0.4 GO:0034457 Mpp10 complex(GO:0034457)
0.1 0.5 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.1 0.8 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.1 1.2 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 0.3 GO:1990745 EARP complex(GO:1990745)
0.1 0.6 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1 0.4 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.1 0.9 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.1 0.4 GO:0070847 core mediator complex(GO:0070847)
0.1 0.3 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.3 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 1.3 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.3 GO:0035101 FACT complex(GO:0035101)
0.0 0.5 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.4 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.2 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 1.1 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.1 GO:0043034 costamere(GO:0043034)
0.0 0.2 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)
0.0 0.4 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.4 GO:1902562 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 0.3 GO:0031306 intrinsic component of mitochondrial outer membrane(GO:0031306)
0.0 0.5 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 2.2 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 1.0 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.2 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.7 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.3 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.7 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 0.1 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.6 GO:0032580 Golgi cisterna membrane(GO:0032580)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0033204 ribonuclease P RNA binding(GO:0033204)
0.2 0.9 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.1 0.8 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.1 1.0 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.1 1.0 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.1 0.3 GO:0031151 histone methyltransferase activity (H3-K79 specific)(GO:0031151)
0.1 0.5 GO:0016361 activin receptor activity, type I(GO:0016361)
0.1 1.0 GO:0043028 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.1 1.6 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 0.5 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.1 1.2 GO:0008301 DNA binding, bending(GO:0008301)
0.1 2.0 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 0.4 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 0.2 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.8 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.5 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.9 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.2 GO:0008743 L-threonine 3-dehydrogenase activity(GO:0008743)
0.0 0.8 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 1.0 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.8 GO:0031267 small GTPase binding(GO:0031267)
0.0 0.7 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.1 GO:0004788 thiamine diphosphokinase activity(GO:0004788) thiamine binding(GO:0030975)
0.0 1.0 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.3 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.3 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.2 GO:0098847 single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.0 0.5 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 1.0 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.1 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.5 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.3 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.0 1.3 GO:0003724 RNA helicase activity(GO:0003724)
0.0 0.7 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.4 GO:0042805 actinin binding(GO:0042805)
0.0 0.4 GO:0016875 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 0.1 GO:0004408 holocytochrome-c synthase activity(GO:0004408)
0.0 0.3 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 2.9 GO:0042802 identical protein binding(GO:0042802)
0.0 0.6 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 0.2 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 0.3 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.1 GO:0016972 thiol oxidase activity(GO:0016972)
0.0 0.1 GO:0004122 cystathionine beta-synthase activity(GO:0004122)
0.0 0.3 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.0 0.2 GO:0051428 peptide hormone receptor binding(GO:0051428)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.5 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 0.4 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.7 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.9 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.7 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 1.0 PID AURORA B PATHWAY Aurora B signaling
0.0 0.5 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.3 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 1.0 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.4 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.3 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.3 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.4 PID MYC PATHWAY C-MYC pathway
0.0 0.6 SIG CHEMOTAXIS Genes related to chemotaxis
0.0 0.3 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 0.4 PID PI3KCI PATHWAY Class I PI3K signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.1 0.9 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 1.0 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 1.0 REACTOME KINESINS Genes involved in Kinesins
0.0 0.5 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.9 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.3 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.7 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 0.4 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.5 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.0 0.5 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.4 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.3 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 0.9 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.5 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.9 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.4 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.3 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 0.8 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.3 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.7 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.0 0.4 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.5 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway