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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for tbx15_tbx1_mgaa_tbx4

Z-value: 0.84

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Transcription factors associated with tbx15_tbx1_mgaa_tbx4

Gene Symbol Gene ID Gene Info
tbx15
ENSDARG00000002582 T-box transcription factor 15
tbx1
ENSDARG00000031891 T-box transcription factor 1
mgaa
ENSDARG00000078784 MAX dimerization protein MGA a
tbx4
ENSDARG00000030058 T-box transcription factor 4
tbx4
ENSDARG00000113067 T-box transcription factor 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
mgaadr11_v1_chr17_+_10570906_105709060.897.2e-07Click!
tbx1dr11_v1_chr5_+_15203421_152034210.223.8e-01Click!
tbx4dr11_v1_chr15_+_27387555_27387555-0.204.2e-01Click!
tbx15dr11_v1_chr9_-_21067673_210676730.087.7e-01Click!

Activity profile of tbx15_tbx1_mgaa_tbx4 motif

Sorted Z-values of tbx15_tbx1_mgaa_tbx4 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr21_-_3700334 2.56 ENSDART00000137844
atp8b1
ATPase phospholipid transporting 8B1
chr19_-_5332784 1.82 ENSDART00000010373
krt1-19d
keratin, type 1, gene 19d
chr9_-_32912638 1.64 ENSDART00000110582
fam160a2
family with sequence similarity 160, member A2
chr20_+_21268795 1.28 ENSDART00000090016
nudt14
nudix (nucleoside diphosphate linked moiety X)-type motif 14
chr22_+_26600834 1.16 ENSDART00000157411
adcy9
adenylate cyclase 9
chr1_-_52505279 1.11 ENSDART00000052907
acy3.1
aspartoacylase (aminocyclase) 3, tandem duplicate 1
chr2_+_36007449 1.06 ENSDART00000161837
lamc2
laminin, gamma 2
chr22_-_3152357 1.05 ENSDART00000170983
lmnb2
lamin B2
chr12_-_5448993 1.05 ENSDART00000181802
tbc1d12b
TBC1 domain family, member 12b
chr1_-_40341306 1.00 ENSDART00000190649
maml3
mastermind-like transcriptional coactivator 3
chr22_+_15959844 0.99 ENSDART00000182201
stil
scl/tal1 interrupting locus
chr20_-_38778479 0.94 ENSDART00000185599
dnajc5ga
DnaJ (Hsp40) homolog, subfamily C, member 5 gamma a
chr23_-_10175898 0.93 ENSDART00000146185
krt5
keratin 5
chr22_+_15960005 0.92 ENSDART00000033617
stil
scl/tal1 interrupting locus
chr1_-_53625142 0.91 ENSDART00000166852
USP34
ubiquitin specific peptidase 34
chr12_-_35386910 0.91 ENSDART00000153453
camk2g1
calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma 1
chr11_-_3535537 0.89 ENSDART00000165329
ENSDART00000009788
ddx19
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 19 (DBP5 homolog, yeast)
chr16_+_16265110 0.86 ENSDART00000191492
setd2
SET domain containing 2
chr7_-_28647959 0.86 ENSDART00000150148
slc7a6
solute carrier family 7 (amino acid transporter light chain, y+L system), member 6
chr14_+_14841685 0.83 ENSDART00000158291
ENSDART00000162039
slbp
stem-loop binding protein
chr21_+_15709061 0.80 ENSDART00000065772
ddt
D-dopachrome tautomerase
chr11_-_25257045 0.79 ENSDART00000130477
snai1a
snail family zinc finger 1a
chr8_+_10862353 0.78 ENSDART00000140717
brpf3b
bromodomain and PHD finger containing, 3b
chr13_-_24880525 0.77 ENSDART00000136624
kat6b
K(lysine) acetyltransferase 6B
chr24_-_2423791 0.75 ENSDART00000190402
rreb1a
ras responsive element binding protein 1a
chr13_-_24906307 0.75 ENSDART00000148191
ENSDART00000189810
kat6b
K(lysine) acetyltransferase 6B
chr22_+_23430688 0.74 ENSDART00000160457
dennd1b
DENN/MADD domain containing 1B
chr2_+_30531726 0.73 ENSDART00000146518
ankrd33bb
ankyrin repeat domain 33Bb
chr9_-_28255029 0.71 ENSDART00000160387
ccnyl1
cyclin Y-like 1
chr8_-_18225968 0.70 ENSDART00000135504
si:ch211-241d21.5
si:ch211-241d21.5
chr19_+_32456974 0.69 ENSDART00000088265
atxn1a
ataxin 1a
chr7_+_17947217 0.68 ENSDART00000101601
cth1
cysteine three histidine 1
chr7_+_39418869 0.67 ENSDART00000169195
CT030188.1

chr7_+_18100996 0.66 ENSDART00000055810
rab1ba
zRAB1B, member RAS oncogene family a
chr3_-_30888415 0.63 ENSDART00000124458
kmt5c
lysine methyltransferase 5C
chr25_+_37397031 0.62 ENSDART00000193643
ENSDART00000169132
slc1a2b
solute carrier family 1 (glial high affinity glutamate transporter), member 2b
chr16_-_13613475 0.62 ENSDART00000139102
dbpb
D site albumin promoter binding protein b
chr21_-_5831413 0.61 ENSDART00000150914
wu:fj64h06
wu:fj64h06
chr15_-_21669618 0.61 ENSDART00000156995
sorl1
sortilin-related receptor, L(DLR class) A repeats containing
chr8_-_1838315 0.61 ENSDART00000114476
ENSDART00000140077
pi4kab
phosphatidylinositol 4-kinase, catalytic, alpha b
chr16_+_50741154 0.61 ENSDART00000101627
IGLON5
zgc:110372
chr9_+_34334156 0.61 ENSDART00000144272
pou2f1b
POU class 2 homeobox 1b
chr3_-_13955878 0.60 ENSDART00000166804
gcdhb
glutaryl-CoA dehydrogenase b
chr14_+_50937757 0.60 ENSDART00000163865
rnf44
ring finger protein 44
chr21_-_21178410 0.60 ENSDART00000185277
ENSDART00000141341
ENSDART00000145872
ENSDART00000079678
ftsj1
FtsJ RNA methyltransferase homolog 1
chr11_-_26832685 0.60 ENSDART00000153519
iqsec1b
IQ motif and Sec7 domain 1b
chr11_-_25257595 0.59 ENSDART00000123567
snai1a
snail family zinc finger 1a
chr11_-_11910225 0.59 ENSDART00000159922
si:ch211-69b7.6
si:ch211-69b7.6
chr17_+_26965351 0.59 ENSDART00000114215
ENSDART00000147192
grhl3
grainyhead-like transcription factor 3
chr7_-_39378903 0.56 ENSDART00000173659
slc8b1
solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
chr16_-_35532937 0.56 ENSDART00000193209
ctps1b
CTP synthase 1b
chr22_-_4439311 0.56 ENSDART00000169317
uhrf1
ubiquitin-like with PHD and ring finger domains 1
chr12_-_17147473 0.55 ENSDART00000106035
stambpl1
STAM binding protein-like 1
chr19_+_791538 0.53 ENSDART00000146554
ENSDART00000138406
tmem79a
transmembrane protein 79a
chr4_+_9028819 0.53 ENSDART00000102893
aldh1l2
aldehyde dehydrogenase 1 family, member L2
chr14_+_10954345 0.53 ENSDART00000106658
zdhhc15b
zinc finger, DHHC-type containing 15b
chr10_+_43994471 0.53 ENSDART00000138242
ENSDART00000186359
cldn5b
claudin 5b
chr6_-_16394528 0.52 ENSDART00000089445
agap1
ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
chr5_+_60919378 0.52 ENSDART00000184915
doc2b
double C2-like domains, beta
chr12_+_32292564 0.51 ENSDART00000152945
ANKFN1
si:ch211-277e21.2
chr6_-_49537646 0.51 ENSDART00000180438
FO704848.1

chr7_+_31120766 0.51 ENSDART00000173703
tjp1a
tight junction protein 1a
chr13_-_8304605 0.51 ENSDART00000080460
atl2
atlastin GTPase 2
chr13_+_21677767 0.50 ENSDART00000165166
mtg1
mitochondrial ribosome-associated GTPase 1
chr22_+_15960514 0.50 ENSDART00000181617
stil
scl/tal1 interrupting locus
chr7_+_39410180 0.49 ENSDART00000168641
CT030188.1

chr11_+_24729346 0.48 ENSDART00000087740
zgc:153953
zgc:153953
chr8_-_11229523 0.48 ENSDART00000002164
unc45b
unc-45 myosin chaperone B
chr3_-_15451097 0.46 ENSDART00000163836
BX784026.1
Danio rerio linker for activation of T cells (lat), mRNA.
chr17_+_58211 0.46 ENSDART00000157642
si:ch1073-209e23.1
si:ch1073-209e23.1
chr5_+_44654535 0.46 ENSDART00000182190
ENSDART00000181872
dapk1
death-associated protein kinase 1
chr7_+_39410393 0.46 ENSDART00000158561
ENSDART00000185173
CT030188.1

chr13_+_25364324 0.45 ENSDART00000187471
chuk
conserved helix-loop-helix ubiquitous kinase
chr8_+_49092077 0.45 ENSDART00000032355
zgc:56525
zgc:56525
chr24_-_32025637 0.45 ENSDART00000180448
ENSDART00000159034
rsu1
Ras suppressor protein 1
chr14_-_7245971 0.45 ENSDART00000108796
stox2b
storkhead box 2b
chr5_-_22615087 0.45 ENSDART00000146035
zgc:113208
zgc:113208
chr18_+_14307059 0.44 ENSDART00000186558
zgc:173742
zgc:173742
chr24_+_19518303 0.44 ENSDART00000027022
ENSDART00000056080
sulf1
sulfatase 1
chr10_+_26944418 0.44 ENSDART00000135493
frmd8
FERM domain containing 8
chr25_-_17918536 0.43 ENSDART00000148660
arntl1a
aryl hydrocarbon receptor nuclear translocator-like 1a
chr18_+_16053455 0.43 ENSDART00000189163
ENSDART00000188269
FO834850.1

chr5_-_37959874 0.43 ENSDART00000031719
mpzl2b
myelin protein zero-like 2b
chr8_+_10869183 0.43 ENSDART00000188111
brpf3b
bromodomain and PHD finger containing, 3b
chr1_-_23110740 0.42 ENSDART00000171848
ENSDART00000086797
ENSDART00000189344
ENSDART00000190858
adgrl3.1
adhesion G protein-coupled receptor L3.1
chr9_-_14992730 0.42 ENSDART00000137117
pard3bb
par-3 family cell polarity regulator beta b
chr9_-_41323746 0.41 ENSDART00000140564
glsb
glutaminase b
chr13_-_27653679 0.41 ENSDART00000142568
rims1a
regulating synaptic membrane exocytosis 1a
chr24_+_19518570 0.41 ENSDART00000056081
sulf1
sulfatase 1
chr1_-_31515746 0.41 ENSDART00000190886
cenpk
centromere protein K
chr17_-_26537928 0.41 ENSDART00000155692
ENSDART00000122366
ccser2a
coiled-coil serine-rich protein 2a
chr25_-_19666107 0.40 ENSDART00000149889
atp2b1b
ATPase plasma membrane Ca2+ transporting 1b
chr7_+_51795667 0.40 ENSDART00000174201
ENSDART00000073839
slc38a7
solute carrier family 38, member 7
chr12_+_34770531 0.40 ENSDART00000153320
slc38a10
solute carrier family 38, member 10
chr18_+_6536293 0.40 ENSDART00000024576
fkbp4
FK506 binding protein 4
chr25_+_7321675 0.39 ENSDART00000104712
ENSDART00000142934
hmg20a
high mobility group 20A
chr10_-_31805923 0.39 ENSDART00000077785
vps26bl
vacuolar protein sorting 26 homolog B, like
chr2_-_6373829 0.39 ENSDART00000081633
si:dkey-119f1.1
si:dkey-119f1.1
chr21_+_38073210 0.39 ENSDART00000186309
ENSDART00000142106
klf8
Kruppel-like factor 8
chr25_+_418932 0.38 ENSDART00000059193
prtgb
protogenin homolog b (Gallus gallus)
chr19_-_7420867 0.38 ENSDART00000081741
rab25a
RAB25, member RAS oncogene family a
chr14_+_28518349 0.38 ENSDART00000159961
stag2b
stromal antigen 2b
chr15_-_25269028 0.38 ENSDART00000078230
ENSDART00000193872
mettl16
methyltransferase like 16
chr13_+_25364753 0.38 ENSDART00000027428
chuk
conserved helix-loop-helix ubiquitous kinase
chr6_+_68220 0.38 ENSDART00000082955
sowahcb
sosondowah ankyrin repeat domain family Cb
chr1_-_34447515 0.38 ENSDART00000143048
lmo7b
LIM domain 7b
chr15_-_23482088 0.37 ENSDART00000185823
ENSDART00000185523
nlrx1
NLR family member X1
chr19_-_31007417 0.37 ENSDART00000048144
rbbp4
retinoblastoma binding protein 4
chr21_+_26726936 0.37 ENSDART00000065392
calm2a
calmodulin 2a (phosphorylase kinase, delta)
chr6_+_36877968 0.36 ENSDART00000155187
traf3ip2l
TRAF3 interacting protein 2-like
chr23_-_46020226 0.36 ENSDART00000160010
SYDE2
synapse defective Rho GTPase homolog 2
chr15_-_18432673 0.35 ENSDART00000146853
ncam1b
neural cell adhesion molecule 1b
chr17_+_51517750 0.35 ENSDART00000180896
ENSDART00000193528
pxdn
peroxidasin
chr5_+_44655148 0.35 ENSDART00000124059
dapk1
death-associated protein kinase 1
chr18_+_6536598 0.34 ENSDART00000149350
fkbp4
FK506 binding protein 4
chr17_-_10738001 0.34 ENSDART00000051526
jmjd7
jumonji domain containing 7
chr13_-_36535128 0.34 ENSDART00000043312
srsf5a
serine/arginine-rich splicing factor 5a
chr9_-_21970067 0.34 ENSDART00000009920
lmo7a
LIM domain 7a
chr6_-_3924723 0.33 ENSDART00000171804
tlk1b
tousled-like kinase 1b
chr13_-_15928934 0.33 ENSDART00000142732
ttl
tubulin tyrosine ligase
chr16_+_20496691 0.33 ENSDART00000182737
ENSDART00000078984
cpvl
carboxypeptidase, vitellogenic-like
chr7_-_18656069 0.33 ENSDART00000021559
coro1b
coronin, actin binding protein, 1B
chr19_+_43669122 0.32 ENSDART00000139151
si:ch211-193k19.1
si:ch211-193k19.1
chr3_+_33367954 0.32 ENSDART00000103161
mpp2a
membrane protein, palmitoylated 2a (MAGUK p55 subfamily member 2)
chr22_-_29640181 0.32 ENSDART00000059882
shoc2
SHOC2 leucine-rich repeat scaffold protein
chr1_+_45925150 0.32 ENSDART00000074689
eif5b
eukaryotic translation initiation factor 5B
chr7_+_29044888 0.31 ENSDART00000086871
gfod2
glucose-fructose oxidoreductase domain containing 2
chr11_-_40647190 0.31 ENSDART00000173217
ENSDART00000173276
ENSDART00000147264
fam213b
family with sequence similarity 213, member B
chr6_-_3924543 0.31 ENSDART00000170584
tlk1b
tousled-like kinase 1b
chr21_+_10866421 0.31 ENSDART00000137858
alpk2
alpha-kinase 2
chr25_-_13659249 0.31 ENSDART00000045488
csnk2a2b
casein kinase 2, alpha prime polypeptide b
chr2_+_33368414 0.31 ENSDART00000077462
slc6a9
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr17_-_10838434 0.30 ENSDART00000064597
lgals3b
lectin, galactoside binding soluble 3b
chr23_+_27779452 0.30 ENSDART00000134785
kmt2d
lysine (K)-specific methyltransferase 2D
chr20_+_41549200 0.29 ENSDART00000135715
fam184a
family with sequence similarity 184, member A
chr13_+_33368140 0.29 ENSDART00000033848
brf1a
BRF1, RNA polymerase III transcription initiation factor a
chr16_-_26676685 0.29 ENSDART00000103431
esrp1
epithelial splicing regulatory protein 1
chr7_+_27455321 0.28 ENSDART00000148417
cyp2r1
cytochrome P450, family 2, subfamily R, polypeptide 1
chr1_+_37195465 0.28 ENSDART00000043855
ENSDART00000192580
ENSDART00000181666
dclk2a
doublecortin-like kinase 2a
chr21_-_26715270 0.28 ENSDART00000053794
banf1
barrier to autointegration factor 1
chr23_+_44644911 0.28 ENSDART00000140799
zgc:85858
zgc:85858
chr17_+_31739418 0.28 ENSDART00000155073
ENSDART00000156180
arhgap5
Rho GTPase activating protein 5
chr22_-_34872533 0.27 ENSDART00000167176
slit1b
slit homolog 1b (Drosophila)
chr12_-_10567188 0.27 ENSDART00000144283
myof
myoferlin
chr16_+_13822137 0.27 ENSDART00000163251
flcn
folliculin
chr12_-_4475890 0.27 ENSDART00000092492
si:ch211-173d10.1
si:ch211-173d10.1
chr8_-_48847772 0.27 ENSDART00000122458
wrap73
WD repeat containing, antisense to TP73
chr15_-_5580093 0.27 ENSDART00000143726
wdr62
WD repeat domain 62
chr10_-_2788668 0.27 ENSDART00000131749
ENSDART00000124356
ENSDART00000085031
ash2l
ash2 (absent, small, or homeotic)-like (Drosophila)
chr23_-_27442544 0.27 ENSDART00000019521
dip2ba
disco-interacting protein 2 homolog Ba
chr5_+_41146786 0.27 ENSDART00000175766
sub1b
SUB1 homolog, transcriptional regulator b
chr23_+_12840080 0.26 ENSDART00000081016
ENSDART00000121697
smc1al
structural maintenance of chromosomes 1A, like
chr10_-_31782616 0.26 ENSDART00000128839
fez1
fasciculation and elongation protein zeta 1 (zygin I)
chr2_-_42552666 0.26 ENSDART00000141399
dip2cb
disco-interacting protein 2 homolog Cb
chr7_-_5431841 0.26 ENSDART00000173073
arhgef11
Rho guanine nucleotide exchange factor (GEF) 11
chr20_-_3238110 0.26 ENSDART00000008077
spint1b
serine peptidase inhibitor, Kunitz type 1 b
chr6_+_32326074 0.26 ENSDART00000042134
ENSDART00000181177
dock7
dedicator of cytokinesis 7
chr19_-_5812319 0.26 ENSDART00000114472
si:ch211-264f5.8
si:ch211-264f5.8
chr10_+_8437930 0.26 ENSDART00000074553
pptc7b
PTC7 protein phosphatase homolog b
chr19_+_32979331 0.26 ENSDART00000078066
spire1a
spire-type actin nucleation factor 1a
chr2_-_7185460 0.26 ENSDART00000092078
rc3h1b
ring finger and CCCH-type domains 1b
chr25_-_10610961 0.26 ENSDART00000153474
ppp6r3
protein phosphatase 6, regulatory subunit 3
chr20_+_23676649 0.25 ENSDART00000035239
nek1
NIMA-related kinase 1
chr19_+_13375838 0.25 ENSDART00000163093
lrp12
low density lipoprotein receptor-related protein 12
chr3_-_42016693 0.25 ENSDART00000184741
ttyh3a
tweety family member 3a
chr19_-_42588510 0.25 ENSDART00000102583
sytl1
synaptotagmin-like 1
chr12_-_26383242 0.25 ENSDART00000152941
usp54b
ubiquitin specific peptidase 54b
chr9_+_33340311 0.25 ENSDART00000140064
ddx3a
DEAD (Asp-Glu-Ala-Asp) box helicase 3a
chr24_-_36095526 0.25 ENSDART00000158145
CABZ01075509.1

chr7_-_42206720 0.25 ENSDART00000110907
itfg1
integrin alpha FG-GAP repeat containing 1
chr12_+_15290800 0.25 ENSDART00000145656
med1
mediator complex subunit 1
chr5_+_19343880 0.25 ENSDART00000148130
acacb
acetyl-CoA carboxylase beta
chr22_-_14475927 0.25 ENSDART00000135768
lrp1ba
low density lipoprotein receptor-related protein 1Ba
chr1_-_49947290 0.25 ENSDART00000141476
sgms2
sphingomyelin synthase 2
chr23_-_29667716 0.24 ENSDART00000158302
ENSDART00000133902
clstn1
calsyntenin 1
chr10_-_44411032 0.24 ENSDART00000111509
CABZ01072096.1

chr22_+_14117078 0.24 ENSDART00000013575
bzw1a
basic leucine zipper and W2 domains 1a
chr10_+_1052591 0.24 ENSDART00000123405
unc5c
unc-5 netrin receptor C
chr21_+_33503835 0.23 ENSDART00000125658
clint1b
clathrin interactor 1b
chr14_-_7207961 0.23 ENSDART00000167994
ENSDART00000166532
stox2b
storkhead box 2b
chr2_-_42396592 0.23 ENSDART00000127136
slco5a1b
solute carrier organic anion transporter family member 5A1b
chr11_+_18873113 0.23 ENSDART00000103969
ENSDART00000103968
magi1b
membrane associated guanylate kinase, WW and PDZ domain containing 1b
chr12_+_48972915 0.23 ENSDART00000170695
lrit1b
leucine-rich repeat, immunoglobulin-like and transmembrane domains 1b
chr18_-_13360106 0.23 ENSDART00000091512
cmip
c-Maf inducing protein
chr13_-_28610965 0.23 ENSDART00000043156
cyp17a1
cytochrome P450, family 17, subfamily A, polypeptide 1
chr19_-_81851 0.23 ENSDART00000172319
hnrnpr
heterogeneous nuclear ribonucleoprotein R
chr2_-_42558549 0.23 ENSDART00000025997
dip2cb
disco-interacting protein 2 homolog Cb
chr2_+_15069011 0.23 ENSDART00000145893
cnn3b
calponin 3, acidic b
chr22_-_16275236 0.23 ENSDART00000149051
cdc14ab
cell division cycle 14Ab
chr14_-_21660548 0.23 ENSDART00000161713
ENSDART00000089845
kdm3b
lysine (K)-specific demethylase 3B
chr17_-_43031763 0.23 ENSDART00000132754
ENSDART00000050399
npc2
Niemann-Pick disease, type C2
chr6_+_13232934 0.23 ENSDART00000089725
ino80db
INO80 complex subunit Db
chr13_-_2283176 0.23 ENSDART00000158462
lrrc1
leucine rich repeat containing 1
chr23_-_29667544 0.22 ENSDART00000059339
clstn1
calsyntenin 1
chr20_-_26846028 0.22 ENSDART00000136687
mylk4b
myosin light chain kinase family, member 4b
chr8_+_47571211 0.22 ENSDART00000131460
plch2a
phospholipase C, eta 2a
chr15_+_42397125 0.22 ENSDART00000169751
tiam1b
T cell lymphoma invasion and metastasis 1b
chr4_-_60049792 0.22 ENSDART00000158199
znf1033
zinc finger protein 1033
chr5_+_31811662 0.22 ENSDART00000023463
uap1l1
UDP-N-acetylglucosamine pyrophosphorylase 1, like 1
chr18_-_11595567 0.22 ENSDART00000098565
CRACR2A
calcium release activated channel regulator 2A

Network of associatons between targets according to the STRING database.

First level regulatory network of tbx15_tbx1_mgaa_tbx4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.4 GO:0071539 protein localization to centrosome(GO:0071539)
0.2 0.7 GO:0030521 androgen receptor signaling pathway(GO:0030521) regulation of androgen receptor signaling pathway(GO:0060765)
0.2 0.6 GO:0034770 histone H4-K20 methylation(GO:0034770) histone H4-K20 trimethylation(GO:0034773)
0.2 1.0 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.2 0.5 GO:0009258 10-formyltetrahydrofolate metabolic process(GO:0009256) 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
0.2 0.8 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.1 0.9 GO:0097198 histone H3-K36 trimethylation(GO:0097198)
0.1 0.7 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.1 0.6 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.1 0.8 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.1 0.5 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.1 0.9 GO:2000290 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910) regulation of myotome development(GO:2000290)
0.1 0.4 GO:0051660 establishment of centrosome localization(GO:0051660)
0.1 0.3 GO:0060092 regulation of synaptic transmission, glycinergic(GO:0060092)
0.1 0.6 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
0.1 1.2 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.1 0.2 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.1 0.6 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.1 0.3 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1 0.2 GO:0030237 female sex determination(GO:0030237) male sex determination(GO:0030238)
0.1 2.6 GO:0045332 phospholipid translocation(GO:0045332)
0.1 0.4 GO:0006972 hyperosmotic response(GO:0006972)
0.1 0.6 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.1 1.4 GO:0008078 mesodermal cell migration(GO:0008078)
0.1 0.9 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.1 0.2 GO:0050787 response to mercury ion(GO:0046689) detoxification of mercury ion(GO:0050787)
0.1 0.2 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.1 0.2 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.1 0.2 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.1 0.3 GO:0048245 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.1 0.5 GO:0071295 cellular response to nutrient(GO:0031670) cellular response to vitamin(GO:0071295)
0.1 0.3 GO:0007344 karyogamy(GO:0000741) pronuclear fusion(GO:0007344)
0.1 0.2 GO:0001783 B cell apoptotic process(GO:0001783) regulation of B cell apoptotic process(GO:0002902) regulation of lymphocyte apoptotic process(GO:0070228)
0.1 0.4 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.1 0.4 GO:0006543 glutamate biosynthetic process(GO:0006537) glutamine catabolic process(GO:0006543)
0.0 0.1 GO:0006678 glucosylceramide metabolic process(GO:0006678)
0.0 0.5 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.0 0.7 GO:2000785 regulation of autophagosome assembly(GO:2000785)
0.0 0.5 GO:0072698 protein localization to microtubule cytoskeleton(GO:0072698)
0.0 0.5 GO:0016188 synaptic vesicle maturation(GO:0016188)
0.0 0.7 GO:0006265 DNA topological change(GO:0006265)
0.0 0.4 GO:0044030 regulation of DNA methylation(GO:0044030)
0.0 0.5 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.0 0.4 GO:0021683 cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.6 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.3 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0 0.2 GO:0097355 protein localization to heterochromatin(GO:0097355)
0.0 0.2 GO:0006531 aspartate metabolic process(GO:0006531)
0.0 0.2 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.2 GO:0032367 intracellular cholesterol transport(GO:0032367)
0.0 0.3 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.1 GO:0061031 endodermal digestive tract morphogenesis(GO:0061031) pancreas morphogenesis(GO:0061113)
0.0 1.9 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.3 GO:0003422 growth plate cartilage morphogenesis(GO:0003422) chondrocyte intercalation involved in growth plate cartilage morphogenesis(GO:0003428)
0.0 0.3 GO:0040038 meiotic cytokinesis(GO:0033206) polar body extrusion after meiotic divisions(GO:0040038)
0.0 0.8 GO:0030537 larval locomotory behavior(GO:0008345) larval behavior(GO:0030537)
0.0 0.1 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.0 0.3 GO:2000758 positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.0 0.2 GO:0048730 epidermis morphogenesis(GO:0048730)
0.0 0.1 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 0.3 GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 0.2 GO:0021846 cell proliferation in forebrain(GO:0021846)
0.0 0.1 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.0 0.4 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.1 GO:0044380 protein localization to cytoskeleton(GO:0044380)
0.0 0.1 GO:0060832 oocyte animal/vegetal axis specification(GO:0060832)
0.0 0.3 GO:0006527 arginine catabolic process(GO:0006527)
0.0 0.1 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.0 0.2 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.0 0.2 GO:0048662 regulation of smooth muscle cell proliferation(GO:0048660) negative regulation of smooth muscle cell proliferation(GO:0048662)
0.0 0.2 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.0 0.9 GO:0072114 pronephros morphogenesis(GO:0072114)
0.0 1.0 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.5 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 0.1 GO:0006266 DNA ligation(GO:0006266) immunoglobulin V(D)J recombination(GO:0033152) DNA ligation involved in DNA repair(GO:0051103)
0.0 0.2 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.0 0.4 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.2 GO:0033700 phospholipid efflux(GO:0033700)
0.0 0.2 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 0.2 GO:0071459 protein localization to kinetochore(GO:0034501) protein localization to chromosome, centromeric region(GO:0071459) positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.0 0.3 GO:0070897 DNA-templated transcriptional preinitiation complex assembly(GO:0070897)
0.0 0.2 GO:2000273 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) positive regulation of receptor activity(GO:2000273)
0.0 0.2 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.1 GO:1990519 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.0 0.3 GO:0016203 muscle attachment(GO:0016203)
0.0 0.6 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.6 GO:0006360 transcription from RNA polymerase I promoter(GO:0006360)
0.0 0.2 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.1 GO:0031048 chromatin silencing by small RNA(GO:0031048)
0.0 0.4 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 0.8 GO:0043113 receptor clustering(GO:0043113)
0.0 0.2 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.1 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.3 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.7 GO:0043297 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.0 0.7 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.5 GO:0006998 nuclear envelope organization(GO:0006998)
0.0 0.1 GO:0000305 response to superoxide(GO:0000303) response to oxygen radical(GO:0000305) removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.0 0.1 GO:0055091 phospholipid homeostasis(GO:0055091)
0.0 0.4 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 1.6 GO:0031497 chromatin assembly(GO:0031497)
0.0 0.6 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.0 0.1 GO:0021631 optic nerve morphogenesis(GO:0021631)
0.0 0.1 GO:0042438 melanin biosynthetic process(GO:0042438)
0.0 0.1 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.4 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.0 0.1 GO:0038065 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065)
0.0 0.2 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 0.0 GO:0048389 intermediate mesoderm development(GO:0048389)
0.0 0.1 GO:0055071 manganese ion homeostasis(GO:0055071)
0.0 0.1 GO:0030104 water homeostasis(GO:0030104)
0.0 0.0 GO:1904729 regulation of intestinal absorption(GO:1904478) regulation of intestinal lipid absorption(GO:1904729)
0.0 0.3 GO:0030261 chromosome condensation(GO:0030261)
0.0 0.0 GO:0009595 detection of biotic stimulus(GO:0009595) detection of bacterium(GO:0016045) detection of other organism(GO:0098543) detection of external biotic stimulus(GO:0098581)
0.0 0.1 GO:0072393 microtubule anchoring at microtubule organizing center(GO:0072393)
0.0 1.2 GO:0031101 fin regeneration(GO:0031101)
0.0 0.2 GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
0.0 0.2 GO:0009409 response to cold(GO:0009409)
0.0 0.9 GO:0009190 cyclic nucleotide biosynthetic process(GO:0009190)
0.0 0.2 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.3 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.5 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 0.2 GO:2000651 positive regulation of sodium ion transport(GO:0010765) positive regulation of sodium ion transmembrane transport(GO:1902307) regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288) positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.0 0.3 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.1 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0097268 cytoophidium(GO:0097268)
0.1 0.8 GO:0008385 IkappaB kinase complex(GO:0008385)
0.1 0.4 GO:0000941 condensed nuclear chromosome inner kinetochore(GO:0000941)
0.1 0.6 GO:0043034 costamere(GO:0043034)
0.1 0.4 GO:0033186 CAF-1 complex(GO:0033186)
0.1 0.9 GO:0045095 keratin filament(GO:0045095)
0.1 0.6 GO:0001650 fibrillar center(GO:0001650)
0.1 1.2 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1 0.4 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 0.2 GO:1902636 kinociliary basal body(GO:1902636)
0.0 0.3 GO:0001772 immunological synapse(GO:0001772)
0.0 0.1 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0 0.3 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.0 0.4 GO:0030904 retromer complex(GO:0030904)
0.0 2.8 GO:0005814 centriole(GO:0005814)
0.0 3.2 GO:0005882 intermediate filament(GO:0005882)
0.0 0.4 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.1 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.0 0.1 GO:0005592 collagen type XI trimer(GO:0005592)
0.0 0.2 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.0 0.5 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.9 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.2 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.3 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 2.1 GO:0055037 recycling endosome(GO:0055037)
0.0 0.4 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.3 GO:0030893 meiotic cohesin complex(GO:0030893)
0.0 2.2 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.1 GO:1990415 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.0 0.1 GO:0070876 SOSS complex(GO:0070876)
0.0 0.3 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 2.1 GO:0016607 nuclear speck(GO:0016607)
0.0 0.2 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.4 GO:0031672 A band(GO:0031672)
0.0 2.2 GO:0043296 apical junction complex(GO:0043296)
0.0 0.3 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.1 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.2 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.4 GO:0048788 cytoskeleton of presynaptic active zone(GO:0048788)
0.0 0.2 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.1 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 0.2 GO:0000813 ESCRT I complex(GO:0000813)
0.0 1.2 GO:0000786 nucleosome(GO:0000786)
0.0 0.2 GO:0030057 desmosome(GO:0030057)
0.0 1.0 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 1.2 GO:0016324 apical plasma membrane(GO:0016324)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.4 GO:0051059 NF-kappaB binding(GO:0051059)
0.2 0.6 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.2 0.8 GO:0008384 IkappaB kinase activity(GO:0008384)
0.2 0.6 GO:0001164 RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.2 0.7 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.2 0.5 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.1 0.6 GO:0004361 glutaryl-CoA dehydrogenase activity(GO:0004361)
0.1 0.6 GO:0003883 CTP synthase activity(GO:0003883)
0.1 0.4 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.1 0.4 GO:0001734 mRNA (N6-adenosine)-methyltransferase activity(GO:0001734)
0.1 1.3 GO:0004046 aminoacylase activity(GO:0004046)
0.1 0.6 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 1.2 GO:0010484 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.1 0.2 GO:1903136 cuprous ion binding(GO:1903136)
0.1 0.3 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 0.2 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.1 0.2 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.1 0.3 GO:0019865 IgE binding(GO:0019863) immunoglobulin binding(GO:0019865)
0.1 0.9 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.1 0.7 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.1 0.5 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 0.8 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.1 GO:0016649 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.0 0.4 GO:0004359 glutaminase activity(GO:0004359)
0.0 0.2 GO:0003977 UDP-N-acetylglucosamine diphosphorylase activity(GO:0003977)
0.0 0.3 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 1.2 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.2 GO:0004307 diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307)
0.0 0.3 GO:0000995 transcription factor activity, core RNA polymerase III binding(GO:0000995)
0.0 0.9 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.2 GO:0090556 phospholipid-translocating ATPase activity(GO:0004012) phosphatidylcholine-translocating ATPase activity(GO:0090554) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.0 0.2 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.0 0.1 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.5 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.4 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003) ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035)
0.0 0.1 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.0 0.1 GO:0008517 folic acid transporter activity(GO:0008517)
0.0 0.6 GO:0070122 isopeptidase activity(GO:0070122)
0.0 0.1 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.4 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.1 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.3 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 1.0 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.1 GO:0070404 6,7-dihydropteridine reductase activity(GO:0004155) NADH binding(GO:0070404)
0.0 0.3 GO:0043495 protein anchor(GO:0043495)
0.0 0.2 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.3 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.2 GO:0008118 N-acetyllactosaminide alpha-2,3-sialyltransferase activity(GO:0008118)
0.0 0.3 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.1 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.0 0.2 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.3 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.0 0.2 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.5 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.6 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.0 0.3 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 1.2 GO:0003724 RNA helicase activity(GO:0003724)
0.0 0.2 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.7 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 1.4 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.0 0.2 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.0 0.1 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.1 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 0.6 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.1 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.0 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.0 0.1 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.7 GO:0019903 protein phosphatase binding(GO:0019903)
0.0 0.1 GO:0052813 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 0.2 GO:0019870 chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.0 0.1 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.1 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.2 GO:0008301 DNA binding, bending(GO:0008301)
0.0 1.8 GO:0000287 magnesium ion binding(GO:0000287)
0.0 0.2 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 1.2 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 1.7 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.9 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.8 PID IFNG PATHWAY IFN-gamma pathway
0.0 2.2 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.3 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 1.0 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.2 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.3 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.4 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.2 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.6 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.3 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.4 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.1 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.2 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.3 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.1 0.8 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.1 0.9 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 0.8 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 0.8 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.1 0.4 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.1 2.7 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.8 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.8 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.5 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 1.3 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 0.2 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.2 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.5 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.2 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.3 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.3 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.2 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.2 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.3 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.2 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.4 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.4 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.1 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport