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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for tbx5a+tbx5b

Z-value: 1.28

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Transcription factors associated with tbx5a+tbx5b

Gene Symbol Gene ID Gene Info
tbx5a
ENSDARG00000024894 T-box transcription factor 5a
tbx5b
ENSDARG00000092060 T-box transcription factor 5b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
tbx5adr11_v1_chr5_-_72289648_722896480.762.7e-04Click!
tbx5bdr11_v1_chr5_+_23152282_23152282-0.341.7e-01Click!

Activity profile of tbx5a+tbx5b motif

Sorted Z-values of tbx5a+tbx5b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr24_-_10021341 4.69 ENSDART00000137250
zgc:173856
zgc:173856
chr24_-_10006158 4.61 ENSDART00000106244
zgc:171750
zgc:171750
chr3_+_43086548 4.53 ENSDART00000163579
si:dkey-43p13.5
si:dkey-43p13.5
chr24_-_9997948 4.51 ENSDART00000136274
si:ch211-146l10.7
si:ch211-146l10.7
chr24_+_10027902 4.23 ENSDART00000175961
ENSDART00000172773
si:ch211-146l10.8
si:ch211-146l10.8
chr11_+_29537756 4.18 ENSDART00000103388
wu:fi42e03
wu:fi42e03
chr20_-_43743700 4.03 ENSDART00000100620
si:dkeyp-50f7.2
si:dkeyp-50f7.2
chr10_+_19596214 3.74 ENSDART00000183110
CABZ01059626.1

chr19_-_34999379 3.57 ENSDART00000051751
zgc:113424
zgc:113424
chr10_+_19569052 3.56 ENSDART00000058425
CABZ01059627.1

chr10_+_19595009 3.19 ENSDART00000112276
zgc:173837
zgc:173837
chr11_-_6452444 3.10 ENSDART00000137879
ENSDART00000134957
ENSDART00000004483
larp6b
La ribonucleoprotein domain family, member 6b
chr4_-_77114795 2.73 ENSDART00000144849
CU467646.2

chr10_-_21542702 2.40 ENSDART00000146761
ENSDART00000134502
zgc:165539
zgc:165539
chr5_-_68333081 2.17 ENSDART00000168786
h1m
linker histone H1M
chr20_-_14114078 1.82 ENSDART00000168434
ENSDART00000104032
si:ch211-223m11.2
si:ch211-223m11.2
chr21_+_30010061 1.66 ENSDART00000182163
ttc1
tetratricopeptide repeat domain 1
chr22_+_39096911 1.66 ENSDART00000157127
ENSDART00000153841
lmcd1
LIM and cysteine-rich domains 1
chr19_-_34995629 1.65 ENSDART00000141704
si:rp71-45k5.2
si:rp71-45k5.2
chr13_+_2894536 1.60 ENSDART00000183678
CABZ01087629.1

chr23_-_31266586 1.54 ENSDART00000139746
si:dkey-261l7.2
si:dkey-261l7.2
chr3_+_49074008 1.53 ENSDART00000168864
zgc:112146
zgc:112146
chr21_-_35325466 1.49 ENSDART00000134780
ENSDART00000145930
ENSDART00000076715
ENSDART00000065341
ENSDART00000162189
ublcp1
ubiquitin-like domain containing CTD phosphatase 1
chr20_+_9124369 1.45 ENSDART00000064150
si:ch211-59d15.9
si:ch211-59d15.9
chr24_-_38079261 1.43 ENSDART00000105662
crp1
C-reactive protein 1
chr4_+_9478500 1.42 ENSDART00000030738
lmf2b
lipase maturation factor 2b
chr18_+_16053455 1.39 ENSDART00000189163
ENSDART00000188269
FO834850.1

chr3_+_32099507 1.34 ENSDART00000044238
zgc:92066
zgc:92066
chr4_+_14981854 1.33 ENSDART00000067046
cax1
cation/H+ exchanger protein 1
chr8_-_38317914 1.30 ENSDART00000125920
pdlim2
PDZ and LIM domain 2 (mystique)
chr22_+_26853254 1.30 ENSDART00000182487
tmem186
transmembrane protein 186
chr10_-_2522588 1.28 ENSDART00000081926
CU856539.1

chr19_+_791538 1.27 ENSDART00000146554
ENSDART00000138406
tmem79a
transmembrane protein 79a
chr3_+_51563695 1.26 ENSDART00000008607
ttyh2l
tweety homolog 2, like
chr19_-_8812891 1.26 ENSDART00000151134
ENSDART00000025385
ENSDART00000180291
cers2a
ceramide synthase 2a
chr21_+_39197628 1.25 ENSDART00000113607
cpdb
carboxypeptidase D, b
chr5_+_26213874 1.25 ENSDART00000193816
ENSDART00000098514
oclnb
occludin b
chr7_-_38689562 1.21 ENSDART00000167209
aplnr2
apelin receptor 2
chr13_-_51846224 1.20 ENSDART00000184663
LT631684.2

chr22_-_17652914 1.19 ENSDART00000138483
si:ch73-243b8.4
si:ch73-243b8.4
chr21_-_34972872 1.19 ENSDART00000023838
lipia
lipase, member Ia
chr23_+_44614056 1.17 ENSDART00000188379
eno3
enolase 3, (beta, muscle)
chr5_-_32338866 1.16 ENSDART00000017956
ENSDART00000047670
dab2
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr15_-_25365319 1.15 ENSDART00000152651
cluha
clustered mitochondria (cluA/CLU1) homolog a
chr15_+_20530649 1.14 ENSDART00000186312
tnfaip1
tumor necrosis factor, alpha-induced protein 1 (endothelial)
chr5_+_57658898 1.13 ENSDART00000074268
ENSDART00000124568
zgc:153929
zgc:153929
chr19_+_37135700 1.12 ENSDART00000103159
smim12
small integral membrane protein 12
chr9_+_27720428 1.12 ENSDART00000112415
lcmt2
leucine carboxyl methyltransferase 2
chr18_-_14274803 1.10 ENSDART00000166643
mlycd
malonyl-CoA decarboxylase
chr24_-_11908115 1.08 ENSDART00000184329
tm9sf1
transmembrane 9 superfamily member 1
chr22_-_17653143 1.07 ENSDART00000089171
hmha1b
histocompatibility (minor) HA-1 b
chr14_+_41318881 1.05 ENSDART00000192137
xkrx
XK, Kell blood group complex subunit-related, X-linked
chr3_-_54607166 1.04 ENSDART00000021977
dnmt1
DNA (cytosine-5-)-methyltransferase 1
chr3_+_58472305 1.04 ENSDART00000154122
si:ch211-165g14.1
si:ch211-165g14.1
chr15_-_45538773 1.03 ENSDART00000113494
MB21D2
Mab-21 domain containing 2
chr7_-_55648336 1.03 ENSDART00000147792
ENSDART00000135304
ENSDART00000131923
pabpn1l
poly(A) binding protein, nuclear 1-like (cytoplasmic)
chr1_+_19602389 1.01 ENSDART00000088933
ENSDART00000141579
ENSDART00000111555
fbxo10
F-box protein 10
chr15_+_43906043 1.01 ENSDART00000010881
naalad2
N-acetylated alpha-linked acidic dipeptidase 2
chr24_+_26337623 1.01 ENSDART00000145637
mynn
myoneurin
chr2_-_38114370 1.00 ENSDART00000131837
chd8
chromodomain helicase DNA binding protein 8
chr3_+_24062748 0.98 ENSDART00000188574
cbx1a
chromobox homolog 1a (HP1 beta homolog Drosophila)
chr14_+_48862987 0.97 ENSDART00000167810
zgc:154054
zgc:154054
chr1_+_49814461 0.96 ENSDART00000132405
lef1
lymphoid enhancer-binding factor 1
chr21_+_39197418 0.96 ENSDART00000076000
cpdb
carboxypeptidase D, b
chr20_-_38778479 0.95 ENSDART00000185599
dnajc5ga
DnaJ (Hsp40) homolog, subfamily C, member 5 gamma a
chr5_-_64355227 0.94 ENSDART00000170787
fam78aa
family with sequence similarity 78, member Aa
chr3_+_40255408 0.94 ENSDART00000074746
smcr8a
Smith-Magenis syndrome chromosome region, candidate 8a
chr12_+_33460794 0.93 ENSDART00000007053
ENSDART00000142716
narf
nuclear prelamin A recognition factor
chr6_-_39199070 0.93 ENSDART00000131793
c1galt1b
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1b
chr2_-_23391266 0.91 ENSDART00000159048
ivns1abpb
influenza virus NS1A binding protein b
chr1_-_524433 0.90 ENSDART00000147610
si:ch73-41e3.7
si:ch73-41e3.7
chr8_-_39984593 0.87 ENSDART00000140127
asphd2
aspartate beta-hydroxylase domain containing 2
chr2_+_11028923 0.86 ENSDART00000076725
acot11a
acyl-CoA thioesterase 11a
chr10_+_38610741 0.86 ENSDART00000126444
mmp13a
matrix metallopeptidase 13a
chr5_+_37966505 0.86 ENSDART00000127648
pafah1b2
platelet-activating factor acetylhydrolase 1b, catalytic subunit 2
chr20_+_1316803 0.85 ENSDART00000152586
ENSDART00000152165
nup43
nucleoporin 43
chr10_-_1961930 0.85 ENSDART00000122446
tdgf1
teratocarcinoma-derived growth factor 1
chr8_-_3312384 0.84 ENSDART00000035965
fut9b
fucosyltransferase 9b
chr10_+_1052591 0.82 ENSDART00000123405
unc5c
unc-5 netrin receptor C
chr22_+_24603930 0.81 ENSDART00000180240
ENSDART00000164256
CU655842.1

chr2_-_9607879 0.81 ENSDART00000056899
txndc12
thioredoxin domain containing 12 (endoplasmic reticulum)
chr10_+_34001444 0.80 ENSDART00000149934
kl
klotho
chr22_+_26600834 0.80 ENSDART00000157411
adcy9
adenylate cyclase 9
chr8_-_38201415 0.80 ENSDART00000155189
pdlim2
PDZ and LIM domain 2 (mystique)
chr7_+_48297842 0.79 ENSDART00000052123
slc25a44b
solute carrier family 25, member 44 b
chr15_-_19443997 0.78 ENSDART00000114936
esamb
endothelial cell adhesion molecule b
chr7_+_40081630 0.77 ENSDART00000173559
zgc:112356
zgc:112356
chr5_-_69482891 0.77 ENSDART00000109487
CABZ01032476.1

chr8_-_39978767 0.77 ENSDART00000083066
asphd2
aspartate beta-hydroxylase domain containing 2
chr3_-_60027255 0.76 ENSDART00000189252
ENSDART00000154684
recql5
RecQ helicase-like 5
chr16_+_10264601 0.76 ENSDART00000186167
mrs2
MRS2 magnesium transporter
chr5_+_29652513 0.76 ENSDART00000035400
tsc1a
TSC complex subunit 1a
chr8_+_3431671 0.75 ENSDART00000017850
ctu1
cytosolic thiouridylase subunit 1 homolog (S. pombe)
chr4_-_18512550 0.75 ENSDART00000045639
rint1
RAD50 interactor 1
chr6_-_37499574 0.74 ENSDART00000023163
jade3
jade family PHD finger 3
chr11_-_18015534 0.74 ENSDART00000181953
qrich1
glutamine-rich 1
chr10_+_16501699 0.73 ENSDART00000121864
slc27a6
solute carrier family 27 (fatty acid transporter), member 6
chr23_-_12158685 0.73 ENSDART00000135035
fam217b
family with sequence similarity 217, member B
chr15_-_11681653 0.73 ENSDART00000180160
fkrp
fukutin related protein
chr12_-_36045283 0.73 ENSDART00000160646
gprc5c
G protein-coupled receptor, class C, group 5, member C
chr17_-_15029639 0.72 ENSDART00000142941
ero1a
endoplasmic reticulum oxidoreductase alpha
chr25_-_29363934 0.72 ENSDART00000166889
nptna
neuroplastin a
chr21_-_36396334 0.71 ENSDART00000183627
mrpl22
mitochondrial ribosomal protein L22
chr12_-_3053873 0.70 ENSDART00000023796
ENSDART00000137148
dcxr
dicarbonyl/L-xylulose reductase
chr8_-_1838315 0.70 ENSDART00000114476
ENSDART00000140077
pi4kab
phosphatidylinositol 4-kinase, catalytic, alpha b
chr25_+_11281970 0.70 ENSDART00000180094
AKAP13
si:dkey-187e18.1
chr17_+_49276061 0.69 ENSDART00000059255
zgc:113176
zgc:113176
chr12_+_1398404 0.69 ENSDART00000026303
rasd1
RAS, dexamethasone-induced 1
chr18_+_36664654 0.69 ENSDART00000128707
ENSDART00000098972
capn12
calpain 12
chr24_-_32173754 0.69 ENSDART00000048633
trdmt1
tRNA aspartic acid methyltransferase 1
chr11_-_41220794 0.69 ENSDART00000192895
mrps16
mitochondrial ribosomal protein S16
chr4_+_20486041 0.69 ENSDART00000017572
ints13
integrator complex subunit 13
chr6_-_11759860 0.68 ENSDART00000151296
si:ch211-162i14.1
si:ch211-162i14.1
chr2_-_23390779 0.68 ENSDART00000020136
ivns1abpb
influenza virus NS1A binding protein b
chr9_+_25840720 0.67 ENSDART00000024572
gtdc1
glycosyltransferase-like domain containing 1
chr9_-_4606463 0.66 ENSDART00000179110
galnt13
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 13
chr10_+_13000669 0.66 ENSDART00000158919
ENSDART00000172625
lpar1
lysophosphatidic acid receptor 1
chr25_-_6049339 0.65 ENSDART00000075184
snx1a
sorting nexin 1a
chr6_+_13232934 0.64 ENSDART00000089725
ino80db
INO80 complex subunit Db
chr6_+_54498220 0.64 ENSDART00000103282
si:ch211-233f11.5
si:ch211-233f11.5
chr5_+_6670945 0.64 ENSDART00000185686
pxna
paxillin a
chr16_+_10264286 0.63 ENSDART00000091377
mrs2
MRS2 magnesium transporter
chr1_+_49415281 0.63 ENSDART00000015007
taf5
TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr17_-_51262430 0.63 ENSDART00000163222
trappc12
trafficking protein particle complex 12
chr10_-_45029041 0.63 ENSDART00000167878
polm
polymerase (DNA directed), mu
chr5_-_26893310 0.62 ENSDART00000126669
lman2lb
lectin, mannose-binding 2-like b
chr13_-_33246154 0.62 ENSDART00000130127
rtf1
RTF1 homolog, Paf1/RNA polymerase II complex component
chr21_-_2287589 0.62 ENSDART00000161554
si:ch73-299h12.4
si:ch73-299h12.4
chr9_+_34221997 0.62 ENSDART00000028617
mpc2
mitochondrial pyruvate carrier 2
chr3_+_15773991 0.61 ENSDART00000089923
znf652
zinc finger protein 652
chr7_+_15313443 0.61 ENSDART00000045385
mespba
mesoderm posterior ba
chr7_-_69795488 0.60 ENSDART00000162414
USP53 (1 of many)
ubiquitin specific peptidase 53
chr13_-_7031033 0.60 ENSDART00000193211
CABZ01061524.1

chr3_+_34986837 0.60 ENSDART00000190341
smarce1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
chr3_+_26288981 0.60 ENSDART00000163500
rhot1a
ras homolog family member T1a
chr25_+_31405266 0.60 ENSDART00000103395
tnnt3a
troponin T type 3a (skeletal, fast)
chr21_-_14251306 0.60 ENSDART00000114715
ENSDART00000181380
man1b1a
mannosidase, alpha, class 1B, member 1a
chr15_-_1765098 0.59 ENSDART00000149980
ENSDART00000093074
bud23
BUD23, rRNA methyltransferase and ribosome maturation factor
chr15_-_1622468 0.59 ENSDART00000149008
ENSDART00000034456
kpna4
karyopherin alpha 4 (importin alpha 3)
chr3_+_35542067 0.59 ENSDART00000146529
ENSDART00000084549
rpusd1
RNA pseudouridylate synthase domain containing 1
chr5_-_31856681 0.59 ENSDART00000187817
pkn3
protein kinase N3
chr6_-_25165693 0.58 ENSDART00000167259
znf326
zinc finger protein 326
chr3_-_23604396 0.57 ENSDART00000078423
atp5mc1
ATP synthase membrane subunit c locus 1
chr18_+_45666489 0.57 ENSDART00000180147
ENSDART00000151351
prrg4
proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
chr1_+_41131481 0.57 ENSDART00000145272
lrpap1
low density lipoprotein receptor-related protein associated protein 1
chr7_-_54320088 0.56 ENSDART00000172396
fadd
Fas (tnfrsf6)-associated via death domain
chr2_-_32237916 0.56 ENSDART00000141418
fam49ba
family with sequence similarity 49, member Ba
chr23_-_6982966 0.56 ENSDART00000033774
ENSDART00000169965
edem2
ER degradation enhancer, mannosidase alpha-like 2
chr8_-_10947205 0.55 ENSDART00000164467
pqlc2
PQ loop repeat containing 2
chr15_+_40079468 0.55 ENSDART00000154947
ngef
neuronal guanine nucleotide exchange factor
chr10_+_8550435 0.54 ENSDART00000185664
tbc1d10ab
TBC1 domain family, member 10Ab
chr25_-_6292270 0.54 ENSDART00000130809
wdr61
WD repeat domain 61
chr1_+_45002971 0.54 ENSDART00000021336
dnaja1
DnaJ (Hsp40) homolog, subfamily A, member 1
chr20_+_3339248 0.54 ENSDART00000108955
mfsd4b
major facilitator superfamily domain containing 4B
chr2_-_15041846 0.54 ENSDART00000139050
si:dkey-10f21.4
si:dkey-10f21.4
chr9_-_28255029 0.54 ENSDART00000160387
ccnyl1
cyclin Y-like 1
chr21_-_38618540 0.54 ENSDART00000036600
slc25a14
solute carrier family 25 (mitochondrial carrier, brain), member 14
chr25_-_6292560 0.53 ENSDART00000153496
wdr61
WD repeat domain 61
chr24_-_2312868 0.53 ENSDART00000140125
ENSDART00000138432
cul2
cullin 2
chr8_+_32722842 0.53 ENSDART00000147594
hmcn2
hemicentin 2
chr13_+_2538636 0.53 ENSDART00000168927
plpp4
phospholipid phosphatase 4
chr9_-_27720612 0.52 ENSDART00000000566
gtf2e1
general transcription factor IIE, polypeptide 1, alpha
chr2_-_58257624 0.52 ENSDART00000098940
foxl2b
forkhead box L2b
chr13_-_31346392 0.52 ENSDART00000134343
rrp12
ribosomal RNA processing 12 homolog
chr13_+_40334727 0.51 ENSDART00000074950
slc25a28
solute carrier family 25 (mitochondrial iron transporter), member 28
chr15_-_28587490 0.51 ENSDART00000186196
ssh2a
slingshot protein phosphatase 2a
chr16_+_26439518 0.51 ENSDART00000041787
trim35-28
tripartite motif containing 35-28
chr2_+_38226624 0.51 ENSDART00000131384
si:ch211-14a17.11
si:ch211-14a17.11
chr2_-_58075414 0.51 ENSDART00000161920
nectin4
nectin cell adhesion molecule 4
chr10_+_42521943 0.50 ENSDART00000010420
ENSDART00000075303
actr1
ARP1 actin related protein 1, centractin
chr7_+_22718251 0.50 ENSDART00000027718
ENSDART00000143341
fxr2
fragile X mental retardation, autosomal homolog 2
chr14_-_7245971 0.50 ENSDART00000108796
stox2b
storkhead box 2b
chr6_-_10725847 0.49 ENSDART00000184567
sp3b
Sp3b transcription factor
chr21_+_6136981 0.49 ENSDART00000065859
ENSDART00000166287
cdk9
cyclin-dependent kinase 9 (CDC2-related kinase)
chr16_+_50434668 0.49 ENSDART00000193500
IGLON5
zgc:110372
chr21_-_14826066 0.49 ENSDART00000067001
noc4l
nucleolar complex associated 4 homolog
chr23_-_27505825 0.49 ENSDART00000137229
ENSDART00000013797
asb8
ankyrin repeat and SOCS box containing 8
chr16_-_30826712 0.49 ENSDART00000122474
ptk2ab
protein tyrosine kinase 2ab
chr17_+_23753975 0.48 ENSDART00000135561
zgc:91976
zgc:91976
chr18_+_36786842 0.48 ENSDART00000123264
si:ch211-160d20.3
si:ch211-160d20.3
chr16_-_42750295 0.48 ENSDART00000176570
slc4a7
solute carrier family 4, sodium bicarbonate cotransporter, member 7
chr7_-_40578733 0.47 ENSDART00000173926
ENSDART00000010035
dnajb6b
DnaJ (Hsp40) homolog, subfamily B, member 6b
chr24_-_2423791 0.47 ENSDART00000190402
rreb1a
ras responsive element binding protein 1a
chr6_+_23026170 0.47 ENSDART00000186683
srp68
signal recognition particle 68
chr3_-_42016693 0.47 ENSDART00000184741
ttyh3a
tweety family member 3a
chr3_+_60607241 0.47 ENSDART00000167512
mfsd11
major facilitator superfamily domain containing 11
chr20_-_54075136 0.47 ENSDART00000074255
mgat2
mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chr22_-_18749313 0.47 ENSDART00000167466
midn
midnolin
chr11_-_25853212 0.46 ENSDART00000145655
tmem51b
transmembrane protein 51b
chr16_-_7793457 0.46 ENSDART00000113483
trim71
tripartite motif containing 71, E3 ubiquitin protein ligase
chr14_+_7699443 0.46 ENSDART00000123139
brd8
bromodomain containing 8
chr6_-_3978919 0.46 ENSDART00000167753
slc25a12
solute carrier family 25 (aspartate/glutamate carrier), member 12
chr5_+_68807170 0.45 ENSDART00000017849
her7
hairy and enhancer of split related-7
chr3_+_56574623 0.45 ENSDART00000130877
rac1b
Rac family small GTPase 1b
chr3_-_25086986 0.45 ENSDART00000050245
xpnpep3
X-prolyl aminopeptidase 3, mitochondrial
chr5_+_36655522 0.45 ENSDART00000015240
capns1a
calpain, small subunit 1 a
chr13_-_8446341 0.45 ENSDART00000080382
epas1b
endothelial PAS domain protein 1b
chr10_-_35149513 0.44 ENSDART00000063434
ENSDART00000131291
ripk4
receptor-interacting serine-threonine kinase 4
chr2_+_5843694 0.44 ENSDART00000182364
dis3l2
DIS3 like 3'-5' exoribonuclease 2
chr4_-_4834347 0.44 ENSDART00000141803
coa6
cytochrome c oxidase assembly factor 6

Network of associatons between targets according to the STRING database.

First level regulatory network of tbx5a+tbx5b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0005997 xylulose metabolic process(GO:0005997)
0.4 1.1 GO:0031591 wybutosine metabolic process(GO:0031590) wybutosine biosynthetic process(GO:0031591)
0.3 0.9 GO:0090008 hypoblast development(GO:0090008)
0.2 1.1 GO:2001293 malonyl-CoA metabolic process(GO:2001293)
0.2 1.0 GO:0032776 DNA methylation on cytosine(GO:0032776)
0.2 1.0 GO:0060784 regulation of cell proliferation involved in tissue homeostasis(GO:0060784)
0.2 0.9 GO:0010586 miRNA metabolic process(GO:0010586)
0.2 0.5 GO:0001120 DNA-templated transcriptional open complex formation(GO:0001112) transcriptional open complex formation at RNA polymerase II promoter(GO:0001113) protein-DNA complex remodeling(GO:0001120)
0.2 0.5 GO:0048496 maintenance of organ identity(GO:0048496)
0.2 0.8 GO:0061687 detoxification of inorganic compound(GO:0061687)
0.2 0.9 GO:0097101 blood vessel endothelial cell fate specification(GO:0097101)
0.1 0.7 GO:0060049 regulation of protein glycosylation(GO:0060049)
0.1 1.2 GO:1905207 regulation of cardiocyte differentiation(GO:1905207) regulation of cardiac muscle cell differentiation(GO:2000725)
0.1 1.0 GO:2000178 negative regulation of neural precursor cell proliferation(GO:2000178)
0.1 0.6 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.1 0.6 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.1 0.4 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500) protein localization to ciliary membrane(GO:1903441)
0.1 0.5 GO:0000338 protein deneddylation(GO:0000338)
0.1 0.9 GO:0031048 chromatin silencing by small RNA(GO:0031048)
0.1 0.7 GO:0032447 tRNA wobble position uridine thiolation(GO:0002143) protein urmylation(GO:0032447)
0.1 0.7 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.1 1.0 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.1 2.1 GO:0015693 magnesium ion transport(GO:0015693)
0.1 0.6 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.1 0.5 GO:0055024 regulation of cardiac muscle tissue development(GO:0055024)
0.1 2.2 GO:0016584 nucleosome positioning(GO:0016584)
0.1 0.7 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.1 0.3 GO:1902767 farnesyl diphosphate biosynthetic process, mevalonate pathway(GO:0010142) isoprenoid biosynthetic process via mevalonate(GO:1902767)
0.1 0.8 GO:0045950 negative regulation of mitotic recombination(GO:0045950)
0.1 0.6 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.1 0.5 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.1 0.5 GO:0015744 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422) malate transmembrane transport(GO:0071423)
0.1 0.4 GO:0048241 copulation(GO:0007620) regulation of epinephrine secretion(GO:0014060) positive regulation of epinephrine secretion(GO:0032812) positive regulation of catecholamine secretion(GO:0033605) penile erection(GO:0043084) epinephrine transport(GO:0048241) epinephrine secretion(GO:0048242) regulation of penile erection(GO:0060405) positive regulation of penile erection(GO:0060406) prolactin secretion(GO:0070459)
0.1 0.6 GO:0000455 enzyme-directed rRNA pseudouridine synthesis(GO:0000455)
0.1 0.3 GO:0071236 cellular response to antibiotic(GO:0071236) cellular response to toxic substance(GO:0097237)
0.1 1.2 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.1 1.2 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.1 0.4 GO:0006015 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.1 0.2 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
0.1 1.1 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.1 0.4 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.1 0.7 GO:0043981 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.1 0.6 GO:0002090 regulation of receptor internalization(GO:0002090)
0.1 0.4 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 0.5 GO:0090497 mesenchymal cell migration(GO:0090497)
0.1 0.8 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.1 0.2 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.1 1.2 GO:0019433 triglyceride catabolic process(GO:0019433)
0.1 4.3 GO:0048484 enteric nervous system development(GO:0048484)
0.1 0.6 GO:0003160 endocardium morphogenesis(GO:0003160)
0.1 0.6 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.1 0.5 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.1 0.4 GO:0044209 AMP salvage(GO:0044209)
0.1 0.2 GO:0035477 regulation of angioblast cell migration involved in selective angioblast sprouting(GO:0035477)
0.1 0.4 GO:0097341 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.1 0.2 GO:0042373 vitamin K metabolic process(GO:0042373)
0.1 0.9 GO:1900077 negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.1 0.7 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.1 0.5 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.1 0.2 GO:2000389 neutrophil extravasation(GO:0072672) regulation of neutrophil extravasation(GO:2000389) positive regulation of neutrophil extravasation(GO:2000391)
0.1 0.4 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.1 0.4 GO:0035860 esophagus smooth muscle contraction(GO:0014846) glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.1 0.4 GO:0021550 medulla oblongata development(GO:0021550) dorsal motor nucleus of vagus nerve development(GO:0021744)
0.1 1.1 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 0.2 GO:0070734 histone H3-K27 methylation(GO:0070734)
0.0 0.2 GO:0070291 N-acylethanolamine metabolic process(GO:0070291)
0.0 0.6 GO:0048696 collateral sprouting in absence of injury(GO:0048669) regulation of collateral sprouting in absence of injury(GO:0048696)
0.0 0.4 GO:0044528 regulation of mitochondrial mRNA stability(GO:0044528)
0.0 0.3 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 0.4 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.0 0.1 GO:0002857 response to tumor cell(GO:0002347) natural killer cell cytokine production(GO:0002370) immune response to tumor cell(GO:0002418) natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of natural killer cell cytokine production(GO:0002727) positive regulation of natural killer cell cytokine production(GO:0002729) positive regulation of response to biotic stimulus(GO:0002833) regulation of response to tumor cell(GO:0002834) positive regulation of response to tumor cell(GO:0002836) regulation of immune response to tumor cell(GO:0002837) positive regulation of immune response to tumor cell(GO:0002839) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860) positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
0.0 0.4 GO:1990402 embryonic liver development(GO:1990402)
0.0 0.1 GO:0021611 facial nerve formation(GO:0021611)
0.0 0.1 GO:0030521 androgen receptor signaling pathway(GO:0030521) regulation of androgen receptor signaling pathway(GO:0060765)
0.0 0.5 GO:0070307 lens fiber cell development(GO:0070307) lens fiber cell morphogenesis(GO:0070309)
0.0 0.8 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.5 GO:0046512 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.0 0.7 GO:0030216 keratinocyte differentiation(GO:0030216)
0.0 0.6 GO:0061055 myotome development(GO:0061055)
0.0 0.4 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.0 0.3 GO:1901224 positive regulation of NIK/NF-kappaB signaling(GO:1901224)
0.0 0.3 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.0 0.4 GO:0060005 reflex(GO:0060004) vestibular reflex(GO:0060005)
0.0 0.5 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0 0.8 GO:0001757 somite specification(GO:0001757)
0.0 0.7 GO:0051642 centrosome localization(GO:0051642)
0.0 0.3 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.4 GO:2000036 regulation of stem cell population maintenance(GO:2000036)
0.0 0.1 GO:0045932 negative regulation of muscle contraction(GO:0045932)
0.0 0.1 GO:0060330 regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0 0.1 GO:0097688 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.0 0.4 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.0 0.9 GO:0048246 macrophage chemotaxis(GO:0048246)
0.0 0.1 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.0 0.1 GO:1990173 protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) protein localization to nucleoplasm(GO:1990173)
0.0 0.3 GO:0071539 protein localization to centrosome(GO:0071539)
0.0 0.6 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.1 GO:0035767 endothelial cell chemotaxis(GO:0035767)
0.0 0.5 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.2 GO:0006285 base-excision repair, AP site formation(GO:0006285)
0.0 0.6 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.7 GO:0070593 dendrite self-avoidance(GO:0070593)
0.0 0.3 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 0.3 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 0.6 GO:0032784 regulation of DNA-templated transcription, elongation(GO:0032784)
0.0 0.3 GO:0035677 posterior lateral line neuromast hair cell development(GO:0035677)
0.0 0.5 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 0.6 GO:0006942 regulation of striated muscle contraction(GO:0006942)
0.0 0.7 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.0 1.1 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.0 0.2 GO:0035141 medial fin morphogenesis(GO:0035141)
0.0 0.6 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.1 GO:0019284 L-methionine biosynthetic process from S-adenosylmethionine(GO:0019284)
0.0 0.1 GO:1901492 positive regulation of lymphangiogenesis(GO:1901492)
0.0 0.7 GO:0016180 snRNA processing(GO:0016180)
0.0 0.4 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.0 0.5 GO:0009408 response to heat(GO:0009408)
0.0 0.6 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.6 GO:0050870 positive regulation of homotypic cell-cell adhesion(GO:0034112) positive regulation of T cell activation(GO:0050870) positive regulation of leukocyte cell-cell adhesion(GO:1903039)
0.0 0.4 GO:0042761 very long-chain fatty acid metabolic process(GO:0000038) very long-chain fatty acid biosynthetic process(GO:0042761)
0.0 0.3 GO:0061647 histone H3-K9 methylation(GO:0051567) histone H3-K9 modification(GO:0061647)
0.0 0.6 GO:0007568 aging(GO:0007568)
0.0 0.2 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0 0.7 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.0 0.4 GO:1902622 regulation of neutrophil migration(GO:1902622)
0.0 0.5 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.0 1.2 GO:0055088 lipid homeostasis(GO:0055088)
0.0 0.3 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.3 GO:0098962 regulation of postsynaptic neurotransmitter receptor activity(GO:0098962)
0.0 0.6 GO:0015908 fatty acid transport(GO:0015908)
0.0 0.5 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.9 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 0.3 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.4 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.8 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 0.1 GO:2000582 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.5 GO:0006826 iron ion transport(GO:0006826)
0.0 0.3 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 0.1 GO:0045852 pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.0 0.4 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.1 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.1 GO:0031179 peptide modification(GO:0031179)
0.0 1.3 GO:0006637 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.0 0.4 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.1 GO:0006517 protein deglycosylation(GO:0006517)
0.0 1.7 GO:0006821 chloride transport(GO:0006821)
0.0 2.0 GO:0051604 protein maturation(GO:0051604)
0.0 0.1 GO:0055014 atrial cardiac muscle cell development(GO:0055014)
0.0 0.5 GO:0008643 carbohydrate transport(GO:0008643)
0.0 0.3 GO:0044773 mitotic DNA damage checkpoint(GO:0044773)
0.0 0.3 GO:0032482 Rab protein signal transduction(GO:0032482)
0.0 0.1 GO:0031055 chromatin remodeling at centromere(GO:0031055) CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.4 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.4 GO:0006360 transcription from RNA polymerase I promoter(GO:0006360)
0.0 0.1 GO:0035678 neuromast hair cell morphogenesis(GO:0035678)
0.0 0.3 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.1 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.2 1.1 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.2 0.5 GO:0030689 Noc complex(GO:0030689)
0.2 0.6 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.2 0.8 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.1 0.6 GO:0044609 DBIRD complex(GO:0044609)
0.1 0.4 GO:0030062 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.1 0.4 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 0.5 GO:1902737 dendritic spine neck(GO:0044326) dendritic filopodium(GO:1902737)
0.1 1.0 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 0.4 GO:0000941 condensed nuclear chromosome inner kinetochore(GO:0000941)
0.1 0.4 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.1 0.7 GO:0070062 extracellular exosome(GO:0070062)
0.1 0.4 GO:0031310 integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
0.1 0.9 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 0.5 GO:0005673 transcription factor TFIIE complex(GO:0005673)
0.1 0.4 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.1 1.6 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 0.9 GO:0031080 nuclear pore outer ring(GO:0031080)
0.1 0.5 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.1 0.2 GO:0043614 multi-eIF complex(GO:0043614)
0.1 0.4 GO:0005845 mRNA cap binding complex(GO:0005845)
0.1 0.6 GO:0030904 retromer complex(GO:0030904)
0.1 1.1 GO:0032039 integrator complex(GO:0032039)
0.1 0.4 GO:0001650 fibrillar center(GO:0001650)
0.0 0.3 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.5 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.6 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 1.0 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 2.5 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 1.0 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.5 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 0.6 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.3 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.6 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 1.1 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 2.2 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.6 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.7 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.1 GO:0044214 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.0 0.4 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.4 GO:0000178 exosome (RNase complex)(GO:0000178)
0.0 0.4 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 1.7 GO:0034707 chloride channel complex(GO:0034707)
0.0 1.1 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.3 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.3 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.2 GO:0045240 dihydrolipoyl dehydrogenase complex(GO:0045240) oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.4 GO:0060170 ciliary membrane(GO:0060170)
0.0 0.2 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.7 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 2.1 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.5 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.2 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.1 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.3 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 3.9 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 0.5 GO:0016605 PML body(GO:0016605)
0.0 0.3 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.2 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.0 1.1 GO:0000786 nucleosome(GO:0000786)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0051139 calcium:proton antiporter activity(GO:0015369) metal ion:proton antiporter activity(GO:0051139)
0.2 1.2 GO:0060182 apelin receptor activity(GO:0060182)
0.2 0.9 GO:0005521 lamin binding(GO:0005521)
0.2 0.8 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.2 1.7 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.2 0.9 GO:0035197 siRNA binding(GO:0035197)
0.2 1.2 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.1 0.4 GO:0001734 mRNA (N6-adenosine)-methyltransferase activity(GO:0001734)
0.1 1.3 GO:0015924 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.1 1.0 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 0.4 GO:0001163 RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.1 0.3 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.1 1.2 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.1 0.5 GO:0015140 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131) malate transmembrane transporter activity(GO:0015140)
0.1 2.1 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 0.7 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1 2.1 GO:0051393 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.1 0.7 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 2.2 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 0.5 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.1 0.4 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.1 0.3 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.1 0.8 GO:0009378 four-way junction helicase activity(GO:0009378)
0.1 1.3 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.1 0.2 GO:0000703 oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity(GO:0000703)
0.1 0.8 GO:0005042 netrin receptor activity(GO:0005042)
0.1 0.5 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 1.0 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 0.4 GO:0004001 adenosine kinase activity(GO:0004001)
0.1 0.6 GO:0045309 protein phosphorylated amino acid binding(GO:0045309) phosphoprotein binding(GO:0051219)
0.1 0.2 GO:0016649 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.1 0.9 GO:0008422 beta-glucosidase activity(GO:0008422)
0.1 0.6 GO:0048019 receptor antagonist activity(GO:0048019)
0.1 2.8 GO:0004180 carboxypeptidase activity(GO:0004180)
0.1 0.9 GO:0005537 mannose binding(GO:0005537)
0.1 0.6 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.1 0.4 GO:0017040 ceramidase activity(GO:0017040)
0.1 0.4 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.1 0.8 GO:0070697 activin receptor binding(GO:0070697)
0.1 0.9 GO:0005123 death receptor binding(GO:0005123)
0.1 0.3 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.1 0.7 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.1 0.5 GO:0035198 miRNA binding(GO:0035198)
0.1 0.5 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.1 0.6 GO:0030172 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.1 1.0 GO:0002039 p53 binding(GO:0002039)
0.1 1.0 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.7 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.9 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 1.5 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.0 0.5 GO:0031994 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
0.0 0.3 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.0 0.4 GO:0052812 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.0 0.3 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.6 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.0 0.5 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.1 GO:0070051 fibrinogen binding(GO:0070051)
0.0 0.6 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.0 0.4 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.5 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.1 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.3 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.2 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 0.5 GO:0015145 glucose transmembrane transporter activity(GO:0005355) monosaccharide transmembrane transporter activity(GO:0015145) hexose transmembrane transporter activity(GO:0015149)
0.0 0.4 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.2 GO:0048039 ubiquinone binding(GO:0048039)
0.0 0.6 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.9 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.2 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.4 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.2 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.1 GO:0032183 SUMO binding(GO:0032183)
0.0 0.6 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.4 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.3 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.4 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.6 GO:0004698 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.0 0.7 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 0.7 GO:0000049 tRNA binding(GO:0000049)
0.0 0.2 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.1 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.6 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.2 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.1 GO:0051380 norepinephrine binding(GO:0051380)
0.0 0.1 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.0 0.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.3 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.8 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 1.5 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.3 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.1 GO:0050218 propionate-CoA ligase activity(GO:0050218)
0.0 0.5 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 1.2 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.3 GO:0030552 cAMP binding(GO:0030552)
0.0 0.1 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.0 1.1 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.0 0.5 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.3 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.1 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.2 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.1 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.1 GO:0032052 bile acid binding(GO:0032052)
0.0 0.3 GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.0 0.1 GO:0000048 peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.0 1.1 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.5 GO:0045182 translation regulator activity(GO:0045182)
0.0 0.2 GO:0070628 proteasome binding(GO:0070628)
0.0 0.4 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.4 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.0 GO:1901612 phosphatidic acid binding(GO:0070300) phosphatidylglycerol binding(GO:1901611) cardiolipin binding(GO:1901612)
0.0 0.2 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 1.0 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.1 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 0.2 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.1 0.6 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.9 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.8 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.8 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.8 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.6 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.5 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.9 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 1.9 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.5 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 1.2 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.4 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.5 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 0.5 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.3 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.0 PID VEGFR1 PATHWAY VEGFR1 specific signals

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.2 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.1 1.0 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.1 0.9 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 0.6 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 1.5 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.2 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.9 REACTOME FGFR LIGAND BINDING AND ACTIVATION Genes involved in FGFR ligand binding and activation
0.0 0.7 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.5 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 1.8 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.7 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 1.6 REACTOME RNA POL II PRE TRANSCRIPTION EVENTS Genes involved in RNA Polymerase II Pre-transcription Events
0.0 0.8 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.2 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.4 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.4 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.5 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 0.2 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.7 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.1 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.1 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.7 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.2 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.0 0.3 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.4 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 0.3 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.2 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.4 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.1 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.5 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.0 0.1 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.1 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.3 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis