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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for tgif1

Z-value: 1.24

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Transcription factors associated with tgif1

Gene Symbol Gene ID Gene Info
tgif1
ENSDARG00000059337 TGFB-induced factor homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
tgif1dr11_v1_chr24_-_9294134_92941340.762.6e-04Click!

Activity profile of tgif1 motif

Sorted Z-values of tgif1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr23_+_39963599 1.69 ENSDART00000166539
fyco1a
FYVE and coiled-coil domain containing 1a
chr25_+_19238175 1.52 ENSDART00000110730
ENSDART00000193619
ENSDART00000154420
ppip5k1b
diphosphoinositol pentakisphosphate kinase 1b
chr6_-_11362871 1.27 ENSDART00000151125
pcnt
pericentrin
chr2_+_23808640 1.27 ENSDART00000024619
gorasp1a
golgi reassembly stacking protein 1a
chr13_+_47821524 1.13 ENSDART00000109978
zc3h6
zinc finger CCCH-type containing 6
chr13_+_7575563 1.13 ENSDART00000146592
gbf1
golgi brefeldin A resistant guanine nucleotide exchange factor 1
chr25_+_418932 1.09 ENSDART00000059193
prtgb
protogenin homolog b (Gallus gallus)
chr13_+_26703922 1.06 ENSDART00000020946
fancl
Fanconi anemia, complementation group L
chr23_-_10175898 1.06 ENSDART00000146185
krt5
keratin 5
chr22_-_29640181 1.03 ENSDART00000059882
shoc2
SHOC2 leucine-rich repeat scaffold protein
chr7_-_42206720 1.03 ENSDART00000110907
itfg1
integrin alpha FG-GAP repeat containing 1
chr12_+_2993523 0.95 ENSDART00000082297
lrrc45
leucine rich repeat containing 45
chr15_-_31516558 0.92 ENSDART00000156427
ENSDART00000156072
ENSDART00000156047
hmgb1b
high mobility group box 1b
chr2_-_32386791 0.91 ENSDART00000056634
ubtfl
upstream binding transcription factor, like
chr3_-_4501026 0.90 ENSDART00000163052
zgc:162198
zgc:162198
chr16_-_51072406 0.89 ENSDART00000083777
ago3a
argonaute RISC catalytic component 3a
chr13_+_45524475 0.89 ENSDART00000074567
ENSDART00000019113
maco1b
macoilin 1b
chr11_+_37652870 0.88 ENSDART00000129918
kif17
kinesin family member 17
chr2_-_42558549 0.87 ENSDART00000025997
dip2cb
disco-interacting protein 2 homolog Cb
chr17_-_24587686 0.86 ENSDART00000143084
aftphb
aftiphilin b
chr20_+_19175031 0.86 ENSDART00000138028
blk
BLK proto-oncogene, Src family tyrosine kinase
chr21_+_37477001 0.85 ENSDART00000114778
amot
angiomotin
chr24_+_744713 0.84 ENSDART00000067764
stk17a
serine/threonine kinase 17a
chr20_+_21268795 0.84 ENSDART00000090016
nudt14
nudix (nucleoside diphosphate linked moiety X)-type motif 14
chr3_-_21137362 0.83 ENSDART00000104051
cdipt
CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase)
chr5_-_3991655 0.81 ENSDART00000159368
myo19
myosin XIX
chr10_+_33393829 0.80 ENSDART00000163458
ENSDART00000115379
zgc:153345
zgc:153345
chr2_+_54844755 0.80 ENSDART00000170428
rnf126
ring finger protein 126
chr5_-_39171302 0.79 ENSDART00000020808
paqr3a
progestin and adipoQ receptor family member IIIa
chr20_+_25712276 0.79 ENSDART00000121585
ENSDART00000185772
cep135
centrosomal protein 135
chr18_-_39787040 0.79 ENSDART00000169916
dmxl2
Dmx-like 2
chr7_+_41887429 0.79 ENSDART00000115090
gpt2
glutamic pyruvate transaminase (alanine aminotransferase) 2
chr20_+_25711718 0.78 ENSDART00000033436
cep135
centrosomal protein 135
chr7_+_42206543 0.77 ENSDART00000112543
phkb
phosphorylase kinase, beta
chr15_+_30126971 0.77 ENSDART00000100214
nufip2
nuclear fragile X mental retardation protein interacting protein 2
chr21_+_36623162 0.76 ENSDART00000027459
grk6
G protein-coupled receptor kinase 6
chr19_-_47832853 0.76 ENSDART00000170988
ago4
argonaute RISC catalytic component 4
chr25_+_3549401 0.75 ENSDART00000166312
ccdc77
coiled-coil domain containing 77
chr7_+_36467796 0.75 ENSDART00000146202
aktip
akt interacting protein
chr6_-_39037613 0.75 ENSDART00000098906
tns2b
tensin 2b
chr3_+_39579393 0.74 ENSDART00000055170
cln3
ceroid-lipofuscinosis, neuronal 3
chr11_-_34577034 0.74 ENSDART00000133302
ENSDART00000184367
pfkfb4a
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4a
chr4_-_815871 0.74 ENSDART00000067455
dpysl5b
dihydropyrimidinase-like 5b
chr25_-_18948816 0.72 ENSDART00000091549
nt5dc3
5'-nucleotidase domain containing 3
chr21_-_11367271 0.72 ENSDART00000151000
ENSDART00000151465
zgc:162472
zgc:162472
chr20_-_4049862 0.72 ENSDART00000158057
sprtn
SprT-like N-terminal domain
chr7_+_35193832 0.72 ENSDART00000189002
zdhhc1
zinc finger, DHHC-type containing 1
chr13_-_18011168 0.71 ENSDART00000144813
march8
membrane-associated ring finger (C3HC4) 8
chr19_-_8880688 0.70 ENSDART00000039629
celf3a
cugbp, Elav-like family member 3a
chr3_-_40051425 0.70 ENSDART00000146700
llgl1
lethal giant larvae homolog 1 (Drosophila)
chr22_+_17214389 0.70 ENSDART00000187083
ENSDART00000159468
ENSDART00000129109
ENSDART00000090107
nrd1b
nardilysin b (N-arginine dibasic convertase)
chr12_-_5455936 0.69 ENSDART00000109305
tbc1d12b
TBC1 domain family, member 12b
chr22_+_30089054 0.69 ENSDART00000185369
add3a
adducin 3 (gamma) a
chr7_+_36467315 0.69 ENSDART00000138893
aktip
akt interacting protein
chr1_-_43905252 0.69 ENSDART00000135477
ENSDART00000132089
si:dkey-22i16.3
si:dkey-22i16.3
chr23_-_24682244 0.69 ENSDART00000104035
ctdsp2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
chr2_-_42492201 0.69 ENSDART00000180762
ENSDART00000009093
esyt2a
extended synaptotagmin-like protein 2a
chr1_-_24349759 0.69 ENSDART00000142740
ENSDART00000177989
lrba
LPS-responsive vesicle trafficking, beach and anchor containing
chr2_+_44518636 0.69 ENSDART00000153733
pask
PAS domain containing serine/threonine kinase
chr8_+_17167876 0.68 ENSDART00000134665
cenph
centromere protein H
chr24_+_3478871 0.68 ENSDART00000111491
ENSDART00000134598
ENSDART00000142407
wdr37
WD repeat domain 37
chr3_+_53240562 0.65 ENSDART00000031234
stxbp2
syntaxin binding protein 2
chr5_-_13766651 0.65 ENSDART00000134064
mxd1
MAX dimerization protein 1
chr6_-_42336987 0.64 ENSDART00000128777
ENSDART00000075601
fancd2
Fanconi anemia, complementation group D2
chr7_-_31921687 0.64 ENSDART00000146720
lin7c
lin-7 homolog C (C. elegans)
chr16_-_29164379 0.64 ENSDART00000132589
mef2d
myocyte enhancer factor 2d
chr11_-_43226255 0.64 ENSDART00000172929
sptbn1
spectrin, beta, non-erythrocytic 1
chr17_+_26753967 0.64 ENSDART00000025096
larp1b
La ribonucleoprotein domain family, member 1B
chr24_+_23791758 0.64 ENSDART00000066655
ENSDART00000146580
mybl1
v-myb avian myeloblastosis viral oncogene homolog-like 1
chr23_+_7710721 0.63 ENSDART00000186852
ENSDART00000161193
kif3b
kinesin family member 3B
chr25_+_15938880 0.63 ENSDART00000089035
ppfibp2b
PTPRF interacting protein, binding protein 2b (liprin beta 2)
chr6_+_48206535 0.63 ENSDART00000075172
cttnbp2nla
CTTNBP2 N-terminal like a
chr12_+_33320884 0.62 ENSDART00000188988
csnk1db
casein kinase 1, delta b
chr11_+_13423776 0.62 ENSDART00000102553
homer3b
homer scaffolding protein 3b
chr14_+_16036139 0.62 ENSDART00000190733
prelid1a
PRELI domain containing 1a
chr14_+_26439227 0.62 ENSDART00000054183
gpr137
G protein-coupled receptor 137
chr13_+_35689749 0.62 ENSDART00000158726
psme4a
proteasome activator subunit 4a
chr8_-_18899427 0.62 ENSDART00000079840
rorca
RAR-related orphan receptor C a
chr12_-_3840664 0.62 ENSDART00000160967
taok2b
TAO kinase 2b
chr7_-_39378903 0.62 ENSDART00000173659
slc8b1
solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
chr19_+_9111550 0.61 ENSDART00000088336
setdb1a
SET domain, bifurcated 1a
chr7_+_42206847 0.61 ENSDART00000149250
phkb
phosphorylase kinase, beta
chr2_+_27652386 0.61 ENSDART00000188261
tmem68
transmembrane protein 68
chr23_-_29667544 0.60 ENSDART00000059339
clstn1
calsyntenin 1
chr24_+_37370064 0.60 ENSDART00000185870
si:ch211-183d21.3
si:ch211-183d21.3
chr18_+_15937610 0.60 ENSDART00000061134
ENSDART00000154505
itpr2
inositol 1,4,5-trisphosphate receptor, type 2
chr15_-_23936276 0.59 ENSDART00000137569
appbp2
amyloid beta precursor protein (cytoplasmic tail) binding protein 2
chr13_-_1427240 0.59 ENSDART00000145867
znf451
zinc finger protein 451
chr5_-_37341044 0.59 ENSDART00000084675
wdr44
WD repeat domain 44
chr11_-_15874974 0.59 ENSDART00000166551
ENSDART00000129526
ENSDART00000165836
rap1ab
RAP1A, member of RAS oncogene family b
chr3_+_47322494 0.58 ENSDART00000102202
ppap2d
phosphatidic acid phosphatase type 2D
chr21_+_13233377 0.58 ENSDART00000142569
specc1lb
sperm antigen with calponin homology and coiled-coil domains 1-like b
chr1_+_53321878 0.58 ENSDART00000143909
tbc1d9
TBC1 domain family, member 9 (with GRAM domain)
chr8_+_9699111 0.57 ENSDART00000111853
gripap1
GRIP1 associated protein 1
chr12_+_38563073 0.57 ENSDART00000009172
ttyh2
tweety family member 2
chr12_+_48674381 0.57 ENSDART00000105309
uros
uroporphyrinogen III synthase
chr9_+_21977383 0.57 ENSDART00000135032
si:dkey-57a22.11
si:dkey-57a22.11
chr18_+_17493859 0.56 ENSDART00000090754
si:dkey-102f14.5
si:dkey-102f14.5
chr20_-_43786515 0.56 ENSDART00000004601
laptm4a
lysosomal protein transmembrane 4 alpha
chr11_-_16975190 0.56 ENSDART00000122222
suclg2
succinate-CoA ligase, GDP-forming, beta subunit
chr14_-_32876280 0.56 ENSDART00000173168
si:rp71-46j2.7
si:rp71-46j2.7
chr21_+_25765734 0.55 ENSDART00000021664
cldnb
claudin b
chr4_-_7875808 0.55 ENSDART00000162276
nudt5
nudix (nucleoside diphosphate linked moiety X)-type motif 5
chr8_+_53311965 0.55 ENSDART00000130104
gnb1a
guanine nucleotide binding protein (G protein), beta polypeptide 1a
chr8_+_12118097 0.55 ENSDART00000081819
endog
endonuclease G
chr9_-_5916693 0.55 ENSDART00000115404
ENSDART00000148792
GPR89A
si:ch73-390b10.2
chr1_-_6028876 0.55 ENSDART00000168117
si:ch1073-345a8.1
si:ch1073-345a8.1
chr13_+_39277178 0.54 ENSDART00000113259
si:dkey-85a20.4
si:dkey-85a20.4
chr15_-_4415917 0.54 ENSDART00000062874
atp1b3b
ATPase Na+/K+ transporting subunit beta 3b
chr2_-_39759059 0.54 ENSDART00000007333
slc25a36a
solute carrier family 25 (pyrimidine nucleotide carrier ), member 36a
chr16_-_20932896 0.54 ENSDART00000180646
tax1bp1b
Tax1 (human T-cell leukemia virus type I) binding protein 1b
chr5_-_15283509 0.54 ENSDART00000052712
gnb1l
guanine nucleotide binding protein (G protein), beta polypeptide 1-like
chr7_+_24006875 0.54 ENSDART00000033755
homezb
homeobox and leucine zipper encoding b
chr5_+_25760112 0.54 ENSDART00000088011
ENSDART00000182046
tmem2
transmembrane protein 2
chr16_-_31790285 0.54 ENSDART00000184655
chd4b
chromodomain helicase DNA binding protein 4b
chr21_+_15870752 0.54 ENSDART00000122015
fam169ab
family with sequence similarity 169, member Ab
chr13_+_18366299 0.53 ENSDART00000133057
ccar1
cell division cycle and apoptosis regulator 1
chr6_+_58280936 0.53 ENSDART00000155244
ralgapb
Ral GTPase activating protein, beta subunit (non-catalytic)
chr20_-_45708962 0.53 ENSDART00000124283
gpcpd1
glycerophosphocholine phosphodiesterase 1
chr25_+_4541211 0.53 ENSDART00000129978
pnpla2
patatin-like phospholipase domain containing 2
chr7_-_38714544 0.53 ENSDART00000139382
fbxo3
F-box protein 3
chr11_+_4953964 0.53 ENSDART00000092552
ptprga
protein tyrosine phosphatase, receptor type, g a
chr2_-_26642831 0.53 ENSDART00000132854
ENSDART00000087714
ENSDART00000132651
u2surp
U2 snRNP-associated SURP domain containing
chr8_+_17168114 0.52 ENSDART00000183901
cenph
centromere protein H
chr6_-_57539141 0.52 ENSDART00000156967
itcha
itchy E3 ubiquitin protein ligase a
chr6_+_21227621 0.52 ENSDART00000193583
prkca
protein kinase C, alpha
chr10_-_15849027 0.52 ENSDART00000184682
tjp2a
tight junction protein 2a (zona occludens 2)
chr6_-_37744430 0.52 ENSDART00000150177
ENSDART00000149722
nipa2
non imprinted in Prader-Willi/Angelman syndrome 2 (human)
chr14_+_22397251 0.52 ENSDART00000185239
ENSDART00000124072
ENSDART00000054977
atp7a
ATPase copper transporting alpha
chr10_+_35347993 0.52 ENSDART00000131350
si:dkey-259j3.5
si:dkey-259j3.5
chr11_+_18216404 0.52 ENSDART00000086437
tmcc1b
transmembrane and coiled-coil domain family 1b
chr21_-_43428040 0.51 ENSDART00000148325
stk26
serine/threonine protein kinase 26
chr8_+_2656681 0.51 ENSDART00000185067
ENSDART00000165943
fam102aa
family with sequence similarity 102, member Aa
chr8_+_13064750 0.51 ENSDART00000039878
sap30bp
SAP30 binding protein
chr24_-_21511737 0.51 ENSDART00000109587
rnf6
ring finger protein (C3H2C3 type) 6
chr19_-_24267823 0.51 ENSDART00000132430
s100v2
S100 calcium binding protein V2
chr24_+_10414028 0.50 ENSDART00000193257
myca
MYC proto-oncogene, bHLH transcription factor a
chr1_-_11878845 0.50 ENSDART00000163971
ENSDART00000123431
iqce
IQ motif containing E
chr6_+_37752781 0.50 ENSDART00000154364
herc2
HECT and RLD domain containing E3 ubiquitin protein ligase 2
chr24_+_39034090 0.50 ENSDART00000185763
capn15
calpain 15
chr15_+_42559910 0.50 ENSDART00000075785
cldn17
claudin 17
chr6_+_48041759 0.50 ENSDART00000140086
si:dkey-92f12.2
si:dkey-92f12.2
chr3_-_31715714 0.50 ENSDART00000051542
ccdc47
coiled-coil domain containing 47
chr14_+_10954345 0.50 ENSDART00000106658
zdhhc15b
zinc finger, DHHC-type containing 15b
chr19_+_7575141 0.50 ENSDART00000051528
s100u
S100 calcium binding protein U
chr15_+_23443665 0.49 ENSDART00000059369
phykpl
5-phosphohydroxy-L-lysine phospho-lyase
chr5_+_27404946 0.49 ENSDART00000121886
ENSDART00000005025
hdr
hematopoietic death receptor
chr13_+_2732951 0.49 ENSDART00000136977
ENSDART00000114328
wdr11
WD repeat domain 11
chr17_-_15528597 0.49 ENSDART00000150232
fyna
FYN proto-oncogene, Src family tyrosine kinase a
chr1_+_34695373 0.49 ENSDART00000077744
ENSDART00000102118
ENSDART00000135528
gtf2f2a
general transcription factor IIF, polypeptide 2a
chr25_+_28823952 0.49 ENSDART00000067072
nfybb
nuclear transcription factor Y, beta b
chr16_+_38119004 0.49 ENSDART00000132087
pogzb
pogo transposable element derived with ZNF domain b
chr15_-_8856391 0.49 ENSDART00000008273
rab4b
RAB4B, member RAS oncogene family
chr25_-_19666107 0.49 ENSDART00000149889
atp2b1b
ATPase plasma membrane Ca2+ transporting 1b
chr14_+_35464994 0.49 ENSDART00000115307
si:ch211-203d1.3
si:ch211-203d1.3
chr3_-_31784082 0.49 ENSDART00000134201
kcnh6a
potassium voltage-gated channel, subfamily H (eag-related), member 6a
chr3_-_18805225 0.49 ENSDART00000133471
ENSDART00000131758
msrb1a
methionine sulfoxide reductase B1a
chr12_+_20627164 0.48 ENSDART00000190179
stx4
syntaxin 4
chr19_+_7575341 0.48 ENSDART00000134271
s100u
S100 calcium binding protein U
chr8_-_31384607 0.48 ENSDART00000164134
ENSDART00000024872
creb3l3l
cAMP responsive element binding protein 3-like 3 like
chr13_+_35690023 0.48 ENSDART00000128865
ENSDART00000130050
psme4a
proteasome activator subunit 4a
chr25_-_3590923 0.48 ENSDART00000164149
si:ch211-272n13.3
si:ch211-272n13.3
chr25_-_35599887 0.48 ENSDART00000153827
clpxb
caseinolytic mitochondrial matrix peptidase chaperone subunit b
chr7_-_28647959 0.48 ENSDART00000150148
slc7a6
solute carrier family 7 (amino acid transporter light chain, y+L system), member 6
chr5_+_26686639 0.48 ENSDART00000079064
tango2
transport and golgi organization 2 homolog (Drosophila)
chr4_-_5018705 0.48 ENSDART00000154025
strip2
striatin interacting protein 2
chr12_-_35582521 0.48 ENSDART00000162175
ENSDART00000168958
sec24c
SEC24 homolog C, COPII coat complex component
chr15_-_23523222 0.47 ENSDART00000078396
hmbsb
hydroxymethylbilane synthase, b
chr3_-_40254634 0.47 ENSDART00000154562
top3a
DNA topoisomerase III alpha
chr14_+_23970818 0.47 ENSDART00000123338
ENSDART00000124944
kif3a
kinesin family member 3A
chr15_-_3277635 0.47 ENSDART00000189094
slc25a15a
solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15a
chr5_+_31214341 0.46 ENSDART00000133432
atp2a3
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3
chr7_+_38380135 0.46 ENSDART00000174005
rhpn2
rhophilin, Rho GTPase binding protein 2
chr21_-_11054876 0.46 ENSDART00000146576
nedd4l
neural precursor cell expressed, developmentally down-regulated 4-like
chr19_-_24267410 0.46 ENSDART00000104083
s100v2
S100 calcium binding protein V2
chr6_+_27090800 0.46 ENSDART00000121558
atg4b
autophagy related 4B, cysteine peptidase
chr7_+_13609457 0.46 ENSDART00000172857
ankdd1a
ankyrin repeat and death domain containing 1A
chr8_+_29636431 0.46 ENSDART00000133047
smarcad1a
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 a
chr5_-_69041102 0.46 ENSDART00000161561
ank1a
ankyrin 1, erythrocytic a
chr5_+_872299 0.46 ENSDART00000130042
fubp3
far upstream element (FUSE) binding protein 3
chr12_-_18898413 0.46 ENSDART00000181281
ENSDART00000121866
desi1b
desumoylating isopeptidase 1b
chr18_+_15271993 0.46 ENSDART00000099777
si:dkey-103i16.6
si:dkey-103i16.6
chr25_-_4482449 0.46 ENSDART00000056278
ENSDART00000149425
slc25a22a
solute carrier family 25 member 22a
chr7_+_17908235 0.46 ENSDART00000077113
mta2
metastasis associated 1 family, member 2
chr10_+_26669177 0.46 ENSDART00000143402
si:ch73-52f15.5
si:ch73-52f15.5
chr13_-_36535128 0.45 ENSDART00000043312
srsf5a
serine/arginine-rich splicing factor 5a
chr1_+_41588170 0.45 ENSDART00000139175
si:dkey-56e3.2
si:dkey-56e3.2
chr9_+_35014728 0.45 ENSDART00000100700
gabpa
GA binding protein transcription factor, alpha subunit
chr13_-_23756700 0.45 ENSDART00000057612
rgs17
regulator of G protein signaling 17
chr11_-_21404044 0.45 ENSDART00000080116
ikbke
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
chr23_+_13528053 0.45 ENSDART00000162217
uckl1b
uridine-cytidine kinase 1-like 1b
chr7_+_39664055 0.45 ENSDART00000146171
zgc:158564
zgc:158564
chr12_-_35582683 0.45 ENSDART00000167933
sec24c
SEC24 homolog C, COPII coat complex component
chr11_+_11120532 0.45 ENSDART00000026135
ENSDART00000189872
ly75
lymphocyte antigen 75
chr21_-_38619305 0.45 ENSDART00000139178
slc25a14
solute carrier family 25 (mitochondrial carrier, brain), member 14
chr23_-_14918276 0.45 ENSDART00000179831
ndrg3b
ndrg family member 3b
chr19_-_12212692 0.45 ENSDART00000142077
ENSDART00000151599
ENSDART00000140834
ENSDART00000078781
znf706
zinc finger protein 706
chr5_+_28770273 0.45 ENSDART00000114473
trafd1
TRAF-type zinc finger domain containing 1
chr24_+_10413484 0.45 ENSDART00000111014
myca
MYC proto-oncogene, bHLH transcription factor a
chr10_-_32890617 0.44 ENSDART00000134922
kctd7
potassium channel tetramerization domain containing 7

Network of associatons between targets according to the STRING database.

First level regulatory network of tgif1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.7 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.3 0.9 GO:0001783 B cell apoptotic process(GO:0001783) regulation of B cell apoptotic process(GO:0002902) regulation of lymphocyte apoptotic process(GO:0070228)
0.3 0.8 GO:0032847 regulation of cellular pH reduction(GO:0032847) synaptic vesicle lumen acidification(GO:0097401) regulation of synaptic vesicle lumen acidification(GO:1901546)
0.3 1.6 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.2 0.7 GO:0000066 mitochondrial ornithine transport(GO:0000066) mitochondrial L-ornithine transmembrane transport(GO:1990575)
0.2 0.8 GO:0071788 endoplasmic reticulum tubular network maintenance(GO:0071788)
0.2 1.0 GO:1990918 double-strand break repair involved in meiotic recombination(GO:1990918)
0.2 0.6 GO:0097095 frontonasal suture morphogenesis(GO:0097095)
0.2 1.1 GO:0007289 spermatid nucleus differentiation(GO:0007289) sperm chromatin condensation(GO:0035092) spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.2 0.5 GO:0006864 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.2 0.7 GO:0099623 regulation of membrane repolarization(GO:0060306) regulation of ventricular cardiac muscle cell membrane repolarization(GO:0060307) regulation of cardiac muscle cell membrane repolarization(GO:0099623) ventricular cardiac muscle cell membrane repolarization(GO:0099625)
0.2 0.9 GO:0023041 neuronal signal transduction(GO:0023041)
0.2 0.7 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.2 1.3 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.2 0.6 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.1 0.4 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.1 0.6 GO:0099563 modification of synaptic structure(GO:0099563)
0.1 1.1 GO:0070874 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.1 0.5 GO:0010898 regulation of triglyceride catabolic process(GO:0010896) positive regulation of triglyceride catabolic process(GO:0010898)
0.1 0.5 GO:1902165 regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902165)
0.1 0.6 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.1 0.9 GO:0098937 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937) anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
0.1 2.0 GO:0035278 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.1 0.5 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.1 0.7 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.1 0.6 GO:1902804 negative regulation of neurotransmitter secretion(GO:0046929) response to cAMP(GO:0051591) cellular response to cAMP(GO:0071320) negative regulation of synaptic vesicle transport(GO:1902804) negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.1 0.8 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.1 0.7 GO:0019427 acetate metabolic process(GO:0006083) acetyl-CoA biosynthetic process from acetate(GO:0019427)
0.1 0.7 GO:0015809 arginine transport(GO:0015809)
0.1 0.8 GO:2000650 negative regulation of sodium ion transmembrane transporter activity(GO:2000650)
0.1 1.4 GO:0006020 inositol metabolic process(GO:0006020)
0.1 0.5 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.1 0.3 GO:2000008 regulation of protein localization to cell surface(GO:2000008) negative regulation of protein localization to cell surface(GO:2000009)
0.1 0.4 GO:0042415 norepinephrine metabolic process(GO:0042415)
0.1 0.8 GO:0044211 CTP salvage(GO:0044211)
0.1 0.3 GO:1905072 cardiac jelly development(GO:1905072)
0.1 0.3 GO:0060571 invagination involved in gastrulation with mouth forming second(GO:0055109) morphogenesis of an epithelial fold(GO:0060571)
0.1 0.4 GO:0006114 glycerol biosynthetic process(GO:0006114) alditol biosynthetic process(GO:0019401)
0.1 1.4 GO:0045022 early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.1 0.3 GO:0051026 chiasma assembly(GO:0051026)
0.1 0.6 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.1 0.4 GO:0032370 positive regulation of lipid transport(GO:0032370)
0.1 1.3 GO:0061647 histone H3-K9 methylation(GO:0051567) histone H3-K9 modification(GO:0061647)
0.1 0.3 GO:0060631 regulation of meiosis I(GO:0060631)
0.1 0.3 GO:0061687 detoxification of inorganic compound(GO:0061687)
0.1 0.3 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.1 0.4 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.1 0.3 GO:0038093 Fc receptor signaling pathway(GO:0038093)
0.1 1.1 GO:0032785 negative regulation of DNA-templated transcription, elongation(GO:0032785) negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.1 0.3 GO:0097037 heme export(GO:0097037)
0.1 0.3 GO:0032053 ciliary basal body organization(GO:0032053) negative regulation of centriole elongation(GO:1903723)
0.1 0.2 GO:0015882 L-ascorbic acid transport(GO:0015882) L-ascorbic acid metabolic process(GO:0019852)
0.1 0.5 GO:0018160 peptidyl-pyrromethane cofactor linkage(GO:0018160)
0.1 0.6 GO:0043584 nose development(GO:0043584)
0.1 0.3 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.1 0.5 GO:0030262 apoptotic DNA fragmentation(GO:0006309) cellular component disassembly involved in execution phase of apoptosis(GO:0006921) apoptotic nuclear changes(GO:0030262)
0.1 0.3 GO:0030224 monocyte differentiation(GO:0030224)
0.1 0.2 GO:1990535 posterior lateral line ganglion development(GO:0048917) neuron projection maintenance(GO:1990535)
0.1 1.2 GO:0051382 kinetochore assembly(GO:0051382)
0.1 0.2 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.1 0.5 GO:0034334 adherens junction maintenance(GO:0034334)
0.1 0.7 GO:0032878 regulation of establishment or maintenance of cell polarity(GO:0032878)
0.1 0.2 GO:0032263 guanine salvage(GO:0006178) GMP salvage(GO:0032263) guanine biosynthetic process(GO:0046099)
0.1 0.4 GO:0006013 mannose metabolic process(GO:0006013)
0.1 0.4 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.1 0.8 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.1 0.3 GO:0090153 regulation of sphingolipid biosynthetic process(GO:0090153) negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060) regulation of membrane lipid metabolic process(GO:1905038) regulation of ceramide biosynthetic process(GO:2000303)
0.1 1.1 GO:0015693 magnesium ion transport(GO:0015693)
0.1 2.3 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.1 0.6 GO:1902624 positive regulation of neutrophil migration(GO:1902624)
0.1 0.3 GO:1901841 regulation of high voltage-gated calcium channel activity(GO:1901841) negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 0.2 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.1 0.9 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.1 1.1 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1 0.2 GO:0070987 error-free translesion synthesis(GO:0070987)
0.1 0.3 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.1 0.2 GO:0019284 L-methionine biosynthetic process from S-adenosylmethionine(GO:0019284)
0.1 0.3 GO:1904867 protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) protein localization to nucleoplasm(GO:1990173)
0.1 0.2 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
0.1 0.4 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.1 0.3 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.1 0.2 GO:0009162 deoxyribonucleoside monophosphate metabolic process(GO:0009162)
0.1 0.3 GO:0003232 bulbus arteriosus development(GO:0003232)
0.1 1.0 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.1 0.8 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.1 0.2 GO:0070131 regulation of mitochondrial translation(GO:0070129) positive regulation of mitochondrial translation(GO:0070131)
0.1 0.3 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.1 0.2 GO:0015824 L-alanine transport(GO:0015808) proline transport(GO:0015824)
0.1 0.2 GO:0009085 lysine biosynthetic process(GO:0009085) lysine biosynthetic process via aminoadipic acid(GO:0019878) L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
0.1 0.2 GO:0036306 embryonic heart tube elongation(GO:0036306)
0.1 0.5 GO:0015810 acidic amino acid transport(GO:0015800) aspartate transport(GO:0015810) L-glutamate transport(GO:0015813) malate-aspartate shuttle(GO:0043490)
0.1 0.8 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1 0.6 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.1 0.3 GO:0007603 phototransduction, visible light(GO:0007603)
0.0 0.2 GO:0090527 actin filament reorganization(GO:0090527)
0.0 0.7 GO:2000785 regulation of autophagosome assembly(GO:2000785)
0.0 0.6 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.0 0.1 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.0 0.4 GO:0046341 CDP-diacylglycerol biosynthetic process(GO:0016024) CDP-diacylglycerol metabolic process(GO:0046341)
0.0 0.2 GO:1903846 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0 0.3 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
0.0 0.2 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
0.0 0.1 GO:1904478 regulation of intestinal absorption(GO:1904478) regulation of intestinal lipid absorption(GO:1904729)
0.0 0.2 GO:0072314 glomerular visceral epithelial cell fate commitment(GO:0072149) glomerular epithelial cell fate commitment(GO:0072314)
0.0 0.1 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.0 0.1 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 1.2 GO:1903845 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.0 0.2 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.6 GO:0055117 regulation of cardiac muscle contraction(GO:0055117)
0.0 0.2 GO:0071422 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) C4-dicarboxylate transport(GO:0015740) malate transport(GO:0015743) succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422) malate transmembrane transport(GO:0071423)
0.0 0.4 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 0.1 GO:0099622 membrane repolarization during action potential(GO:0086011) membrane repolarization during cardiac muscle cell action potential(GO:0086013) cardiac muscle cell membrane repolarization(GO:0099622)
0.0 0.3 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.0 0.3 GO:0071233 response to leucine(GO:0043201) cellular response to leucine(GO:0071233) regulation of response to reactive oxygen species(GO:1901031)
0.0 1.4 GO:0006513 protein monoubiquitination(GO:0006513)
0.0 0.1 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.2 GO:0003228 atrial cardiac muscle tissue development(GO:0003228)
0.0 0.5 GO:0035264 multicellular organism growth(GO:0035264)
0.0 0.2 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.5 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.3 GO:0007288 sperm axoneme assembly(GO:0007288)
0.0 1.7 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.2 GO:0045144 meiotic sister chromatid segregation(GO:0045144) meiotic sister chromatid cohesion(GO:0051177)
0.0 0.4 GO:0000729 DNA double-strand break processing(GO:0000729)
0.0 0.3 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.1 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.0 0.6 GO:0071545 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855) inositol phosphate catabolic process(GO:0071545)
0.0 0.1 GO:0019628 urate catabolic process(GO:0019628) urate metabolic process(GO:0046415)
0.0 0.1 GO:1901224 positive regulation of NIK/NF-kappaB signaling(GO:1901224)
0.0 0.2 GO:0010692 regulation of alkaline phosphatase activity(GO:0010692) negative regulation of alkaline phosphatase activity(GO:0010693)
0.0 0.2 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.1 GO:0090113 regulation of COPII vesicle coating(GO:0003400) regulation of ER to Golgi vesicle-mediated transport by GTP hydrolysis(GO:0090113)
0.0 0.8 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.8 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.4 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 0.3 GO:0021634 optic nerve formation(GO:0021634)
0.0 0.5 GO:0033077 T cell differentiation in thymus(GO:0033077) thymocyte aggregation(GO:0071594)
0.0 0.3 GO:2000273 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) positive regulation of receptor activity(GO:2000273)
0.0 0.1 GO:0000390 spliceosomal complex disassembly(GO:0000390)
0.0 0.8 GO:0016925 protein sumoylation(GO:0016925)
0.0 0.1 GO:0035971 peptidyl-histidine dephosphorylation(GO:0035971)
0.0 0.2 GO:0009180 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180)
0.0 0.3 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.2 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.2 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.4 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.0 0.2 GO:0035881 amacrine cell differentiation(GO:0035881)
0.0 0.1 GO:0006600 creatine metabolic process(GO:0006600) creatine biosynthetic process(GO:0006601)
0.0 0.2 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.0 0.4 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.5 GO:0006265 DNA topological change(GO:0006265)
0.0 1.3 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.0 0.4 GO:0032411 positive regulation of transporter activity(GO:0032411)
0.0 0.2 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.0 0.2 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.2 GO:0006477 protein sulfation(GO:0006477) peptidyl-tyrosine sulfation(GO:0006478)
0.0 0.1 GO:0042148 strand invasion(GO:0042148)
0.0 0.2 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.0 0.2 GO:0033522 histone H2A ubiquitination(GO:0033522)
0.0 0.2 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.0 0.4 GO:0008089 anterograde axonal transport(GO:0008089)
0.0 0.6 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 0.1 GO:0043420 anthranilate metabolic process(GO:0043420)
0.0 0.9 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.0 0.4 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.5 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 1.1 GO:0046579 positive regulation of Ras protein signal transduction(GO:0046579) positive regulation of small GTPase mediated signal transduction(GO:0051057)
0.0 0.3 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.0 0.1 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.2 GO:0090178 establishment of planar polarity of embryonic epithelium(GO:0042249) establishment of planar polarity involved in neural tube closure(GO:0090177) regulation of establishment of planar polarity involved in neural tube closure(GO:0090178) planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.0 0.2 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.0 0.1 GO:0007624 ultradian rhythm(GO:0007624)
0.0 0.1 GO:0009794 regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
0.0 0.2 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.1 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.2 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998)
0.0 0.8 GO:0099500 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.0 0.4 GO:0006998 nuclear envelope organization(GO:0006998)
0.0 1.0 GO:1904029 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.0 0.1 GO:0010039 response to iron ion(GO:0010039)
0.0 1.8 GO:0007030 Golgi organization(GO:0007030)
0.0 0.3 GO:0045116 protein neddylation(GO:0045116)
0.0 0.2 GO:0043901 negative regulation of multi-organism process(GO:0043901)
0.0 0.1 GO:0055107 Golgi to secretory granule transport(GO:0055107)
0.0 0.1 GO:0032964 collagen biosynthetic process(GO:0032964)
0.0 0.4 GO:0036376 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.0 0.3 GO:0009408 response to heat(GO:0009408)
0.0 0.1 GO:0034501 protein localization to kinetochore(GO:0034501) protein localization to chromosome, centromeric region(GO:0071459)
0.0 0.1 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.2 GO:0045444 fat cell differentiation(GO:0045444)
0.0 0.1 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.0 0.2 GO:0061028 establishment of endothelial barrier(GO:0061028)
0.0 0.2 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.0 0.1 GO:0007060 male meiosis chromosome segregation(GO:0007060)
0.0 0.3 GO:0097324 melanocyte migration(GO:0097324)
0.0 0.1 GO:0036445 neuronal stem cell division(GO:0036445) somatic stem cell division(GO:0048103)
0.0 0.1 GO:0010872 regulation of cholesterol esterification(GO:0010872) positive regulation of cholesterol esterification(GO:0010873)
0.0 0.2 GO:0009086 methionine biosynthetic process(GO:0009086)
0.0 0.3 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.5 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 0.9 GO:0030050 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.0 0.1 GO:2000136 pharyngeal muscle development(GO:0043282) cell proliferation involved in heart morphogenesis(GO:0061323) regulation of cell proliferation involved in heart morphogenesis(GO:2000136)
0.0 0.2 GO:1990504 dense core granule exocytosis(GO:1990504)
0.0 0.2 GO:0022615 protein import into peroxisome matrix, docking(GO:0016560) protein to membrane docking(GO:0022615)
0.0 0.1 GO:0030242 pexophagy(GO:0030242)
0.0 0.2 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.0 0.3 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 1.0 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 1.1 GO:0005977 glycogen metabolic process(GO:0005977) cellular glucan metabolic process(GO:0006073) glucan metabolic process(GO:0044042)
0.0 1.5 GO:0032272 negative regulation of actin filament polymerization(GO:0030837) negative regulation of protein polymerization(GO:0032272)
0.0 0.1 GO:0001839 neural plate morphogenesis(GO:0001839)
0.0 0.4 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.0 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.0 0.3 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.1 GO:0042779 tRNA 3'-trailer cleavage(GO:0042779)
0.0 0.2 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.0 0.4 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.3 GO:0051560 mitochondrial calcium ion homeostasis(GO:0051560)
0.0 0.7 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 1.7 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.4 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.2 GO:0000710 meiotic mismatch repair(GO:0000710)
0.0 0.3 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208)
0.0 0.3 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.4 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.0 0.0 GO:0006089 lactate metabolic process(GO:0006089) ketone catabolic process(GO:0042182)
0.0 0.3 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.0 0.1 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.1 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.0 0.1 GO:2001106 regulation of guanyl-nucleotide exchange factor activity(GO:1905097) regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.0 0.1 GO:0045843 negative regulation of striated muscle tissue development(GO:0045843) negative regulation of muscle tissue development(GO:1901862)
0.0 0.5 GO:0051225 spindle assembly(GO:0051225)
0.0 0.2 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.0 0.4 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.0 0.4 GO:0090307 mitotic spindle assembly(GO:0090307) microtubule cytoskeleton organization involved in mitosis(GO:1902850)
0.0 0.1 GO:0003404 optic vesicle morphogenesis(GO:0003404)
0.0 0.8 GO:0050919 negative chemotaxis(GO:0050919)
0.0 1.1 GO:0003341 cilium movement(GO:0003341)
0.0 0.1 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026) negative regulation of microtubule polymerization or depolymerization(GO:0031111)
0.0 1.3 GO:0031098 stress-activated protein kinase signaling cascade(GO:0031098)
0.0 0.1 GO:0055129 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.0 0.3 GO:0051092 positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.0 0.1 GO:0016540 protein autoprocessing(GO:0016540)
0.0 0.3 GO:0009072 aromatic amino acid family metabolic process(GO:0009072)
0.0 0.0 GO:0006517 protein deglycosylation(GO:0006517)
0.0 0.0 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.1 GO:0071691 cardiac muscle thin filament assembly(GO:0071691)
0.0 0.5 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 0.4 GO:0032465 regulation of cytokinesis(GO:0032465)
0.0 0.2 GO:0060079 excitatory postsynaptic potential(GO:0060079)
0.0 0.3 GO:0060030 dorsal convergence(GO:0060030)
0.0 0.1 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.0 0.1 GO:0042537 benzene-containing compound metabolic process(GO:0042537)
0.0 0.3 GO:0051282 sequestering of calcium ion(GO:0051208) release of sequestered calcium ion into cytosol(GO:0051209) regulation of sequestering of calcium ion(GO:0051282) negative regulation of sequestering of calcium ion(GO:0051283)
0.0 0.1 GO:0051155 positive regulation of striated muscle cell differentiation(GO:0051155)
0.0 0.1 GO:0006567 threonine metabolic process(GO:0006566) threonine catabolic process(GO:0006567)
0.0 0.0 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.1 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0 0.6 GO:0030336 negative regulation of cell migration(GO:0030336)
0.0 0.1 GO:0098734 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.1 GO:1990111 spermatoproteasome complex(GO:1990111)
0.2 1.4 GO:0070695 FHF complex(GO:0070695)
0.2 1.7 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.2 0.8 GO:0043291 RAVE complex(GO:0043291)
0.2 0.6 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.1 0.6 GO:0008091 spectrin(GO:0008091)
0.1 0.9 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.1 1.3 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.1 1.0 GO:0042788 polysomal ribosome(GO:0042788)
0.1 0.4 GO:0033186 CAF-1 complex(GO:0033186)
0.1 0.4 GO:0097134 cyclin E1-CDK2 complex(GO:0097134)
0.1 0.6 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.1 0.5 GO:0034657 GID complex(GO:0034657)
0.1 0.5 GO:0016589 NURF complex(GO:0016589)
0.1 0.7 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.1 0.3 GO:0042709 succinate-CoA ligase complex(GO:0042709)
0.1 0.4 GO:1990071 TRAPPII protein complex(GO:1990071)
0.1 0.9 GO:0045095 keratin filament(GO:0045095)
0.1 0.7 GO:0032021 NELF complex(GO:0032021)
0.1 0.9 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1 0.5 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.1 1.4 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.1 0.3 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.1 0.3 GO:0035339 SPOTS complex(GO:0035339)
0.1 1.1 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 0.4 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.1 0.7 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.1 1.1 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 0.6 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.5 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.1 GO:0001534 radial spoke(GO:0001534)
0.0 0.1 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0 0.5 GO:0090533 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
0.0 0.4 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.4 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.5 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.1 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.3 GO:0036156 inner dynein arm(GO:0036156)
0.0 0.3 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.6 GO:0016363 nuclear matrix(GO:0016363)
0.0 3.2 GO:0005871 kinesin complex(GO:0005871)
0.0 1.1 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.2 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.3 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.2 GO:0000798 nuclear cohesin complex(GO:0000798) mitotic cohesin complex(GO:0030892) nuclear mitotic cohesin complex(GO:0034990) nuclear meiotic cohesin complex(GO:0034991)
0.0 0.7 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.2 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.5 GO:0005903 brush border(GO:0005903)
0.0 0.4 GO:0002102 podosome(GO:0002102)
0.0 0.7 GO:0005921 gap junction(GO:0005921)
0.0 3.4 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.1 GO:1990513 CLOCK-BMAL transcription complex(GO:1990513)
0.0 0.4 GO:0044545 NSL complex(GO:0044545)
0.0 1.6 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.3 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.2 GO:0038039 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor heterodimeric complex(GO:0038039) G-protein coupled receptor complex(GO:0097648)
0.0 0.1 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.3 GO:0032300 mismatch repair complex(GO:0032300)
0.0 0.6 GO:0030667 secretory granule membrane(GO:0030667)
0.0 0.9 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.2 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.2 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.3 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.1 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.1 GO:0060171 stereocilium membrane(GO:0060171)
0.0 1.0 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.0 0.4 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 1.7 GO:0005814 centriole(GO:0005814)
0.0 0.4 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.3 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.4 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.2 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.3 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.2 GO:1990246 uniplex complex(GO:1990246)
0.0 0.1 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.1 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.2 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 1.1 GO:0005776 autophagosome(GO:0005776)
0.0 0.1 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0 1.8 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.3 GO:0015030 Cajal body(GO:0015030)
0.0 0.2 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.1 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.6 GO:0031941 filamentous actin(GO:0031941)
0.0 0.4 GO:0071010 U2-type prespliceosome(GO:0071004) prespliceosome(GO:0071010)
0.0 0.1 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.6 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.3 GO:0098843 postsynaptic endocytic zone(GO:0098843) postsynaptic endocytic zone membrane(GO:0098844)
0.0 0.3 GO:0060170 ciliary membrane(GO:0060170)
0.0 0.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.8 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.8 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.1 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.2 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.4 GO:0016605 PML body(GO:0016605)
0.0 0.7 GO:0030141 secretory granule(GO:0030141)
0.0 1.4 GO:0060076 excitatory synapse(GO:0060076)
0.0 0.1 GO:0030914 STAGA complex(GO:0030914)
0.0 0.1 GO:0000153 cytoplasmic ubiquitin ligase complex(GO:0000153)
0.0 0.1 GO:0018444 translation release factor complex(GO:0018444)
0.0 0.3 GO:0043204 perikaryon(GO:0043204)
0.0 1.2 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.7 GO:0000793 condensed chromosome(GO:0000793)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.4 GO:0033857 inositol heptakisphosphate kinase activity(GO:0000829) diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.2 2.0 GO:0035198 miRNA binding(GO:0035198)
0.2 0.5 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.2 0.6 GO:0070182 DNA polymerase binding(GO:0070182)
0.2 0.6 GO:0097016 L27 domain binding(GO:0097016)
0.1 0.4 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 1.3 GO:0043515 kinetochore binding(GO:0043515)
0.1 0.5 GO:2001070 starch binding(GO:2001070)
0.1 0.6 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.1 1.0 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.1 0.5 GO:0033745 L-methionine-(R)-S-oxide reductase activity(GO:0033745)
0.1 0.3 GO:0045545 syndecan binding(GO:0045545)
0.1 0.7 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.1 1.0 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.1 1.1 GO:0016504 peptidase activator activity(GO:0016504)
0.1 0.4 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.1 0.3 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 0.8 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.1 0.5 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.1 0.3 GO:0047760 medium-chain fatty acid-CoA ligase activity(GO:0031956) butyrate-CoA ligase activity(GO:0047760)
0.1 0.3 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.1 0.3 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.1 0.8 GO:0004849 uridine kinase activity(GO:0004849)
0.1 0.5 GO:0032183 SUMO binding(GO:0032183)
0.1 0.5 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.1 0.6 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.1 0.3 GO:0004775 succinate-CoA ligase activity(GO:0004774) succinate-CoA ligase (ADP-forming) activity(GO:0004775) succinate-CoA ligase (GDP-forming) activity(GO:0004776)
0.1 0.3 GO:0003868 4-hydroxyphenylpyruvate dioxygenase activity(GO:0003868)
0.1 0.3 GO:0003988 acetyl-CoA C-acyltransferase activity(GO:0003988)
0.1 0.5 GO:0004418 hydroxymethylbilane synthase activity(GO:0004418)
0.1 0.7 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.1 0.3 GO:0017020 myosin phosphatase regulator activity(GO:0017020)
0.1 0.4 GO:0070548 L-glutamine aminotransferase activity(GO:0070548)
0.1 0.7 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.1 0.2 GO:0055105 ubiquitin-protein transferase inhibitor activity(GO:0055105)
0.1 0.2 GO:0004422 hypoxanthine phosphoribosyltransferase activity(GO:0004422)
0.1 1.8 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 0.3 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.1 0.8 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.1 0.3 GO:0034046 poly(G) binding(GO:0034046)
0.1 0.8 GO:0061665 SUMO ligase activity(GO:0061665)
0.1 0.4 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.1 0.2 GO:0004419 hydroxymethylglutaryl-CoA lyase activity(GO:0004419)
0.1 0.3 GO:1990756 protein binding, bridging involved in substrate recognition for ubiquitination(GO:1990756)
0.1 0.7 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.1 2.8 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 0.8 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.1 0.4 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.1 0.2 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.1 0.3 GO:0008311 double-stranded DNA exodeoxyribonuclease activity(GO:0008309) double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.1 1.2 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 0.3 GO:0097363 protein N-acetylglucosaminyltransferase activity(GO:0016262) protein O-GlcNAc transferase activity(GO:0097363)
0.1 0.9 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.1 0.2 GO:0015180 L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.1 0.2 GO:0061656 SUMO conjugating enzyme activity(GO:0061656)
0.1 0.4 GO:0034452 dynactin binding(GO:0034452)
0.0 0.6 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.9 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.2 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0 0.1 GO:0019777 Atg12 transferase activity(GO:0019777)
0.0 1.5 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.2 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.3 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.2 GO:0015140 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131) malate transmembrane transporter activity(GO:0015140)
0.0 0.5 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.2 GO:0051717 inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity(GO:0051717) phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)
0.0 0.3 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.8 GO:0035497 cAMP response element binding(GO:0035497)
0.0 1.2 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.6 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.2 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.0 0.3 GO:0070728 leucine binding(GO:0070728)
0.0 0.5 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.2 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.3 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.1 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.7 GO:0045159 myosin II binding(GO:0045159)
0.0 0.4 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.3 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 0.2 GO:0004373 glycogen (starch) synthase activity(GO:0004373)
0.0 0.5 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 0.2 GO:0015616 DNA translocase activity(GO:0015616)
0.0 0.5 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.0 0.5 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.2 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.2 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.0 1.0 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.3 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.0 0.4 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.3 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.3 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.2 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.1 GO:0052743 inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659) inositol tetrakisphosphate phosphatase activity(GO:0052743)
0.0 0.3 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0 1.5 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.1 GO:0008397 sterol 12-alpha-hydroxylase activity(GO:0008397)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.3 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.1 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.2 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.2 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.0 0.4 GO:0019870 chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.0 1.7 GO:0008094 DNA-dependent ATPase activity(GO:0008094)
0.0 0.4 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.6 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.3 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.6 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.2 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.8 GO:0042287 MHC protein binding(GO:0042287)
0.0 0.3 GO:0043495 protein anchor(GO:0043495)
0.0 2.2 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.2 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.1 GO:0101006 protein histidine phosphatase activity(GO:0101006)
0.0 0.5 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.4 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.3 GO:0070739 protein-glutamic acid ligase activity(GO:0070739) tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.4 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.2 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.0 0.3 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.1 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.0 0.3 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.3 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.0 0.1 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.3 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.4 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.1 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.3 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.2 GO:0005522 profilin binding(GO:0005522)
0.0 1.1 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.2 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.0 0.9 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.2 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.1 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.1 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 0.2 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 0.2 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.2 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.0 0.6 GO:0016769 transferase activity, transferring nitrogenous groups(GO:0016769)
0.0 0.4 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.1 GO:0042781 3'-tRNA processing endoribonuclease activity(GO:0042781)
0.0 0.4 GO:0016251 obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.0 0.1 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.3 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.4 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.6 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.1 GO:0070888 E-box binding(GO:0070888)
0.0 0.1 GO:0008743 L-threonine 3-dehydrogenase activity(GO:0008743)
0.0 0.5 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.1 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 1.1 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.1 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.0 0.6 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.3 GO:0005080 protein kinase C binding(GO:0005080)
0.0 1.2 GO:0003678 DNA helicase activity(GO:0003678)
0.0 0.8 GO:0030170 pyridoxal phosphate binding(GO:0030170)
0.0 0.6 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.2 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.9 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.4 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.3 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.1 GO:0016728 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.1 GO:0004945 angiotensin type I receptor activity(GO:0001596) angiotensin type II receptor activity(GO:0004945)
0.0 0.6 GO:0019003 GDP binding(GO:0019003)
0.0 0.3 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.1 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.3 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.1 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.2 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.3 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.1 GO:0015172 L-glutamate transmembrane transporter activity(GO:0005313) acidic amino acid transmembrane transporter activity(GO:0015172)
0.0 0.1 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.2 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.2 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.3 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.1 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.0 0.3 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.1 GO:0030507 spectrin binding(GO:0030507)
0.0 0.1 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.2 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.1 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.0 0.2 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.5 GO:0015179 L-amino acid transmembrane transporter activity(GO:0015179)
0.0 0.2 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.2 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.1 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.4 GO:0003774 motor activity(GO:0003774)
0.0 3.2 GO:0051015 actin filament binding(GO:0051015)
0.0 0.3 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.1 1.4 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 2.1 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.9 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 1.0 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 1.0 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.7 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 1.0 PID ATM PATHWAY ATM pathway
0.0 0.4 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.8 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.6 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 1.8 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.4 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 1.0 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.2 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.6 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 1.4 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.8 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.3 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.2 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.1 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.2 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.5 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.0 0.3 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.3 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.7 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.2 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.7 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.0 0.2 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 0.2 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 0.4 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 0.2 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.1 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.0 ST GAQ PATHWAY G alpha q Pathway
0.0 0.3 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.2 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 1.0 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.2 PID ARF 3PATHWAY Arf1 pathway
0.0 0.3 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.3 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.3 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.2 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.1 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.5 PID AR PATHWAY Coregulation of Androgen receptor activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 0.3 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.1 1.1 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.1 1.4 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 0.9 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 0.6 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.1 0.8 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 0.6 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 0.9 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.1 0.9 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.1 1.6 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1 2.6 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.1 1.1 REACTOME CA DEPENDENT EVENTS Genes involved in Ca-dependent events
0.1 0.6 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 1.0 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.3 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 1.0 REACTOME KINESINS Genes involved in Kinesins
0.0 0.1 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.9 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.5 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.3 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.2 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.6 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 1.2 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.5 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.3 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.6 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 2.2 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.0 0.3 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.3 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.6 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.8 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.3 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.4 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.6 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.2 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.4 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.1 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.8 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.5 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.3 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 0.5 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.2 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.6 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.4 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.4 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.1 REACTOME SIGNALING BY SCF KIT Genes involved in Signaling by SCF-KIT
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.2 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.3 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.2 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.4 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.2 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.3 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.0 0.1 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.3 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.1 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism