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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for znf384l

Z-value: 0.87

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Transcription factors associated with znf384l

Gene Symbol Gene ID Gene Info
ENSDARG00000001015 zinc finger protein 384 like

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
znf384ldr11_v1_chr19_-_6983002_69830020.925.0e-08Click!

Activity profile of znf384l motif

Sorted Z-values of znf384l motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_14143344 2.11 ENSDART00000152742
bucky ball 2-like
chr15_+_22394074 1.78 ENSDART00000109931
OAF homolog a (Drosophila)
chr23_+_28322986 1.75 ENSDART00000134710
baculoviral IAP repeat containing 5b
chr11_-_3613558 1.74 ENSDART00000163578
DnaJ (Hsp40) homolog, subfamily C, member 16 like
chr6_+_23809163 1.59 ENSDART00000170402
glutamate-ammonia ligase (glutamine synthase) b
chr2_-_17115256 1.54 ENSDART00000190488
PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)
chr6_-_7109063 1.51 ENSDART00000148548
nonhomologous end-joining factor 1
chr12_-_4249000 1.45 ENSDART00000059298
zgc:92313
chr16_+_35924188 1.45 ENSDART00000165847
SH3 domain containing 21
chr2_+_22416275 1.40 ENSDART00000185179
ENSDART00000172715
protein kinase N2
chr11_-_38554394 1.40 ENSDART00000102858
nuclear casein kinase and cyclin-dependent kinase substrate 1a
chr4_-_27099224 1.36 ENSDART00000048383
cysteine-rich with EGF-like domains 2
chr7_-_4125021 1.34 ENSDART00000167182
ENSDART00000173696
zgc:55733
chr15_+_38308421 1.33 ENSDART00000129941
si:dkey-24p1.6
chr5_+_26212621 1.33 ENSDART00000134432
occludin b
chr17_+_16429826 1.30 ENSDART00000136078
EF-hand calcium binding domain 11
chr7_+_51795667 1.29 ENSDART00000174201
ENSDART00000073839
solute carrier family 38, member 7
chr6_-_40446536 1.29 ENSDART00000153466
TatD DNase domain containing 2
chr13_-_21672131 1.26 ENSDART00000067537
ELOVL family member 6, elongation of long chain fatty acids like
chr2_+_23808640 1.23 ENSDART00000024619
golgi reassembly stacking protein 1a
chr17_+_1544903 1.21 ENSDART00000156244
ENSDART00000112183
centrosomal protein 170B
chr23_-_27822920 1.21 ENSDART00000023094
activin A receptor type 1Ba
chr11_+_5565082 1.19 ENSDART00000112590
ENSDART00000183207
si:ch73-40i7.5
chr15_-_30867594 1.16 ENSDART00000154448
neurofibromin 1a
chr20_+_38543314 1.16 ENSDART00000153416
ENSDART00000020969
ENSDART00000101262
general transcription factor IIIC, polypeptide 2, beta
chr25_+_36292057 1.15 ENSDART00000152329
brambleberry
chr14_+_45028062 1.15 ENSDART00000184717
ENSDART00000185481
ATPase phospholipid transporting 8A1
chr8_-_49725430 1.14 ENSDART00000135675
G kinase anchoring protein 1
chr25_+_36292465 1.14 ENSDART00000152649
brambleberry
chr20_-_13623882 1.13 ENSDART00000125218
ENSDART00000152499
synaptotagmin-like 3
chr6_+_21005725 1.13 ENSDART00000041370
connexin 44.2
chr10_-_22912255 1.11 ENSDART00000131992
si:ch1073-143l10.2
chr17_+_21887823 1.10 ENSDART00000131929
ENSDART00000165192
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1a
chr19_+_9113932 1.09 ENSDART00000060442
SET domain, bifurcated 1a
chr1_+_26676758 1.09 ENSDART00000152299
si:dkey-25o16.4
chr17_+_25871304 1.08 ENSDART00000185143
WAPL cohesin release factor a
chr17_+_32531854 1.07 ENSDART00000123399
GC-rich sequence DNA-binding factor 2
chr24_+_21720304 1.05 ENSDART00000147250
ENSDART00000048273
PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr2_-_38287987 1.03 ENSDART00000185329
ENSDART00000061677
si:ch211-14a17.6
chr1_-_43920371 1.03 ENSDART00000109283
secretory calcium-binding phosphoprotein 7
chr15_-_18115540 1.03 ENSDART00000131639
ENSDART00000047902
archain 1b
chr22_-_17671348 1.03 ENSDART00000137995
tight junction protein 3
chr17_-_8592824 1.02 ENSDART00000127022

chr11_-_15874974 1.02 ENSDART00000166551
ENSDART00000129526
ENSDART00000165836
RAP1A, member of RAS oncogene family b
chr12_+_31783066 0.99 ENSDART00000105584
leucine rich repeat containing 59
chr13_-_45022301 0.99 ENSDART00000183589
ENSDART00000125633
ENSDART00000074787
KH domain containing, RNA binding, signal transduction associated 1a
chr1_+_36772348 0.98 ENSDART00000109314
Rho GTPase activating protein 10
chr4_-_4250317 0.97 ENSDART00000103316
CD9 molecule b
chr5_-_28968964 0.97 ENSDART00000184936
ENSDART00000016628
family with sequence similarity 129, member Bb
chr16_+_22345513 0.96 ENSDART00000078000
zgc:123238
chr23_+_24501918 0.95 ENSDART00000078824
SUZ RNA binding domain containing 1
chr10_+_17371356 0.95 ENSDART00000122663
signal peptide peptidase 3
chr2_-_32688905 0.95 ENSDART00000041146
nuclear receptor binding protein 2a
chr6_-_27108844 0.95 ENSDART00000073883
deoxythymidylate kinase (thymidylate kinase)
chr18_+_35861930 0.94 ENSDART00000185223
protein phosphatase 1, regulatory subunit 13 like
chr22_+_25236888 0.94 ENSDART00000037286
zgc:172218
chr17_-_12758171 0.92 ENSDART00000131564
breast cancer metastasis-suppressor 1-like a
chr23_-_36305874 0.92 ENSDART00000147598
ENSDART00000146986
ENSDART00000086985
ENSDART00000133259
chromobox homolog 5 (HP1 alpha homolog, Drosophila)
chr25_+_8925934 0.92 ENSDART00000073914
1-aminocyclopropane-1-carboxylate synthase homolog (Arabidopsis)(non-functional)
chr10_+_8197827 0.92 ENSDART00000026244
Mtr4 exosome RNA helicase
chr19_+_6938289 0.92 ENSDART00000139122
ENSDART00000178832
flotillin 1b
chr22_-_6562618 0.91 ENSDART00000106100
zgc:171490
chr13_+_22719789 0.90 ENSDART00000057672
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr22_+_25249193 0.89 ENSDART00000171851
si:ch211-226h8.11
chr23_-_36306337 0.89 ENSDART00000142760
ENSDART00000136929
ENSDART00000143340
chromobox homolog 5 (HP1 alpha homolog, Drosophila)
chr13_+_29926326 0.89 ENSDART00000131609
CUE domain containing 2
chr17_+_25187670 0.89 ENSDART00000190873
CLN8, transmembrane ER and ERGIC protein
chr18_+_3634652 0.89 ENSDART00000159913
leucine-rich repeats and calponin homology (CH) domain containing 3
chr22_-_20812822 0.89 ENSDART00000193778
DOT1-like histone H3K79 methyltransferase
chr2_-_47620806 0.88 ENSDART00000038228
adaptor-related protein complex 1, sigma 3 subunit, b
chr20_+_38543542 0.88 ENSDART00000145254
general transcription factor IIIC, polypeptide 2, beta
chr14_+_49153369 0.87 ENSDART00000186170
ENSDART00000181831
nuclear receptor binding SET domain protein 1a
chr4_-_10826575 0.87 ENSDART00000164771
ENSDART00000067256
PTPRF interacting protein, binding protein 1a (liprin beta 1)
chr7_+_36467315 0.86 ENSDART00000138893
akt interacting protein
chr7_-_48251234 0.85 ENSDART00000024062
ENSDART00000098904
cytoplasmic polyadenylation element binding protein 1b
chr8_-_25771474 0.85 ENSDART00000193883
suppressor of variegation 3-9 homolog 1b
chr8_-_36618073 0.84 ENSDART00000047912
G patch domain and KOW motifs
chr20_+_34671386 0.84 ENSDART00000152836
ENSDART00000138226
elongator acetyltransferase complex subunit 3
chr7_-_30560400 0.82 ENSDART00000142680
ENSDART00000142818
SAFB-like, transcription modulator
chr6_-_37749711 0.82 ENSDART00000078324
non imprinted in Prader-Willi/Angelman syndrome 1
chr17_+_28103675 0.81 ENSDART00000188078
zgc:91908
chr6_-_40768654 0.81 ENSDART00000184668
ENSDART00000146470
actin related protein 2/3 complex, subunit 4
chr3_+_53156813 0.81 ENSDART00000114343
bromodomain containing 4
chr15_-_31265375 0.81 ENSDART00000086592
vascular endothelial zinc finger 1b
chr8_+_247163 0.80 ENSDART00000122378
centrosomal protein 120
chr5_-_65662996 0.80 ENSDART00000147707
calmodulin regulated spectrin-associated protein 1b
chr1_-_45213565 0.80 ENSDART00000145757
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39Aa
chr7_-_24838367 0.79 ENSDART00000139455
ENSDART00000012483
ENSDART00000131530
family with sequence similarity 113
chr16_+_46410520 0.79 ENSDART00000131072
rapunzel 2
chr1_-_22652424 0.79 ENSDART00000036797
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr10_-_24765988 0.78 ENSDART00000064463
translocase of inner mitochondrial membrane 10 homolog B (yeast)
chr19_-_32944050 0.77 ENSDART00000137611
antizyme inhibitor 1b
chr14_+_26224541 0.77 ENSDART00000128971
GM2 ganglioside activator
chr8_+_11687254 0.77 ENSDART00000042040
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2a
chr13_+_29926094 0.75 ENSDART00000057528
CUE domain containing 2
chr24_+_37484661 0.75 ENSDART00000165125
ENSDART00000109221
WD repeat domain 90
chr8_+_47683352 0.75 ENSDART00000187320
ENSDART00000192605
dipeptidyl-peptidase 9
chr3_-_55650771 0.74 ENSDART00000162413
axin 2 (conductin, axil)
chr19_+_24324967 0.74 ENSDART00000090081
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4Ab
chr3_-_60856157 0.74 ENSDART00000053502

chr7_-_20241346 0.74 ENSDART00000173619
ENSDART00000127699
si:ch73-335l21.4
chr15_+_23722620 0.72 ENSDART00000011447
SUMO1 activating enzyme subunit 1
chr19_-_2861444 0.71 ENSDART00000169053
C-type lectin domain family 3, member Bb
chr9_+_22632126 0.71 ENSDART00000139434
ets variant 5a
chr23_-_31648026 0.71 ENSDART00000133569
serum/glucocorticoid regulated kinase 1
chr9_-_6618067 0.71 ENSDART00000061585
si:dkeyp-118h3.6
chr5_-_13076779 0.70 ENSDART00000192826
yippee-like 1
chr13_+_46944607 0.70 ENSDART00000187352
F-box protein 5
chr3_-_23574622 0.69 ENSDART00000176012
insulin-like growth factor 2 mRNA binding protein 1
chr9_-_28990649 0.69 ENSDART00000078823
protein tyrosine phosphatase, non-receptor type 4a
chr2_-_44344321 0.69 ENSDART00000084174
ligase I, DNA, ATP-dependent
chr3_-_25054002 0.68 ENSDART00000086768
E1A binding protein p300 b
chr12_+_14084291 0.68 ENSDART00000189734
si:ch211-217a12.1
chr2_-_37803614 0.68 ENSDART00000154124
nuclear factor of activated T cells 4
chr20_+_53368611 0.68 ENSDART00000060432
cell division cycle 40 homolog (S. cerevisiae)
chr13_+_22698215 0.67 ENSDART00000137467
si:ch211-134m17.9
chr5_+_37406358 0.67 ENSDART00000162811
kelch-like family member 13
chr2_+_5406236 0.67 ENSDART00000154167
SFT2 domain containing 3
chr8_+_13700605 0.67 ENSDART00000144516
LON peptidase N-terminal domain and ring finger 1, like
chr10_+_10386435 0.67 ENSDART00000179214
ENSDART00000189799
ENSDART00000193875
sarcosine dehydrogenase
chr25_+_21098675 0.67 ENSDART00000079012
RAD52 homolog, DNA repair protein
chr10_+_8875195 0.66 ENSDART00000141045
integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor), tandem duplicate 3
chr6_+_36821621 0.66 ENSDART00000104157
transmembrane protein 45a
chr23_-_29668286 0.66 ENSDART00000129248
calsyntenin 1
chr3_-_36364903 0.66 ENSDART00000028883
guanine nucleotide binding protein (G protein), alpha 13b
chr14_+_25505468 0.66 ENSDART00000079016
THO complex 3
chr25_-_12805295 0.66 ENSDART00000157629
carbonic anhydrase Va
chr4_-_1801519 0.66 ENSDART00000188604
ENSDART00000135749
nudix (nucleoside diphosphate linked moiety X)-type motif 4b
chr7_-_26497947 0.65 ENSDART00000058910
SRY (sex determining region Y)-box 19b
chr9_-_12659140 0.65 ENSDART00000058565
PTTG1 interacting protein b
chr17_+_50701748 0.65 ENSDART00000191938
ENSDART00000183220
ENSDART00000049464
fermitin family member 2
chr19_-_31035155 0.65 ENSDART00000161882
basic leucine zipper and W2 domains 2
chr24_-_31140356 0.65 ENSDART00000167837
transmembrane protein 56a
chr3_-_40254634 0.65 ENSDART00000154562
DNA topoisomerase III alpha
chr10_+_17345 0.64 ENSDART00000180325
TIP41, TOR signaling pathway regulator-like (S. cerevisiae)
chr20_-_10487951 0.64 ENSDART00000064112
glutaredoxin 5 homolog (S. cerevisiae)
chr10_+_32066537 0.64 ENSDART00000124166
si:dkey-250d21.1
chr19_+_1673599 0.64 ENSDART00000163127
kelch-like family member 7
chr7_-_56766973 0.64 ENSDART00000020967
casein kinase 2, alpha prime polypeptide a
chr3_+_42923275 0.64 ENSDART00000168228
transmembrane protein 184a
chr7_+_17938128 0.64 ENSDART00000141044
metastasis associated 1 family, member 2
chr16_+_33142734 0.63 ENSDART00000138244
rhomboid, veinlet-like 2 (Drosophila)
chr5_+_70271799 0.63 ENSDART00000101316
zinc finger protein 618
chr21_+_4116437 0.63 ENSDART00000167791
ENSDART00000123759
Rap guanine nucleotide exchange factor (GEF) 1b
chr23_+_2704793 0.63 ENSDART00000147953
nuclear receptor coactivator 6
chr23_+_31596194 0.63 ENSDART00000160748
TBP-like 1
chr5_-_67349916 0.63 ENSDART00000144092
MLX interacting protein
chr18_+_18455029 0.63 ENSDART00000165079
siah E3 ubiquitin protein ligase 1
chr19_-_43639331 0.63 ENSDART00000138009
ENSDART00000086138
family with sequence similarity 83, member Hb
chr10_+_32066355 0.62 ENSDART00000062311
si:dkey-250d21.1
chr16_-_21903083 0.62 ENSDART00000165849
SET domain, bifurcated 1b
chr6_+_48206535 0.62 ENSDART00000075172
CTTNBP2 N-terminal like a
chr2_-_58183499 0.62 ENSDART00000172281
ENSDART00000186262
si:ch1073-185p12.2
chr19_-_31035325 0.61 ENSDART00000147504
basic leucine zipper and W2 domains 2
chr7_-_24838857 0.61 ENSDART00000179766
ENSDART00000180892
family with sequence similarity 113
chr6_-_43387920 0.61 ENSDART00000154434
FERM domain containing 4Ba
chr1_-_24255149 0.61 ENSDART00000146960
LPS-responsive vesicle trafficking, beach and anchor containing
chr11_-_4023940 0.61 ENSDART00000058728
ENSDART00000171245
NIMA-related kinase 4
chr7_+_19483277 0.61 ENSDART00000173750
si:ch211-212k18.7
chr5_-_69621227 0.61 ENSDART00000178543
aldehyde dehydrogenase 2 family (mitochondrial), tandem duplicate 2
chr10_+_15454745 0.61 ENSDART00000129441
ENSDART00000123935
ENSDART00000163446
ENSDART00000087680
ENSDART00000193752
erbb2 interacting protein
chr22_+_25088999 0.60 ENSDART00000158225
ribosome binding protein 1b
chr14_+_16036139 0.60 ENSDART00000190733
PRELI domain containing 1a
chr11_+_14333441 0.60 ENSDART00000171969
polypyrimidine tract binding protein 1b
chr2_+_44972720 0.60 ENSDART00000075146
asparagine-linked glycosylation 3 (alpha-1,3-mannosyltransferase)
chr7_-_56766100 0.60 ENSDART00000189934
casein kinase 2, alpha prime polypeptide a
chr4_-_13931293 0.59 ENSDART00000067172
zinc finger CCHC-type and RNA binding motif 1
chr20_-_14462995 0.59 ENSDART00000152418
ENSDART00000044125
gene rich cluster, C10 gene
chr6_+_22104565 0.59 ENSDART00000151747
si:dkey-156n14.5
chr6_-_19310660 0.59 ENSDART00000171110
small ubiquitin-like modifier 2a
chr3_+_27606505 0.59 ENSDART00000150953
ubiquitin specific peptidase 7 (herpes virus-associated)
chr2_+_42871831 0.59 ENSDART00000171393
EFR3 homolog A (S. cerevisiae)
chr16_-_17345377 0.58 ENSDART00000143056
zyxin
chr6_-_18250857 0.58 ENSDART00000159486
APC11 anaphase promoting complex subunit 11 homolog (yeast)
chr23_-_17451264 0.58 ENSDART00000190748
tumor protein D52-like 2b
chr25_+_21098990 0.58 ENSDART00000017488
RAD52 homolog, DNA repair protein
chr5_+_58455488 0.58 ENSDART00000038602
ENSDART00000127958
solute carrier family 37 (glucose-6-phosphate transporter), member 2
chr11_+_2649664 0.57 ENSDART00000166357
si:ch211-160o17.4
chr15_+_2191900 0.57 ENSDART00000185913
arginine/serine-rich coiled-coil 1
chr23_-_29667716 0.57 ENSDART00000158302
ENSDART00000133902
calsyntenin 1
chr7_-_19997095 0.57 ENSDART00000180955
thyroid hormone receptor interactor 6
chr5_+_33289057 0.56 ENSDART00000123210
mediator complex subunit 22
chr23_+_37482727 0.56 ENSDART00000162737
agmatine ureohydrolase (agmatinase)
chr10_+_29771256 0.56 ENSDART00000193195
hypoxia up-regulated 1
chr24_-_3477103 0.56 ENSDART00000143723
isopentenyl-diphosphate delta isomerase 1
chr25_+_19530017 0.56 ENSDART00000144023
SH3-domain GRB2-like 3b
chr5_-_6567464 0.56 ENSDART00000184985
tankyrase 1 binding protein 1
chr3_-_23575007 0.55 ENSDART00000155282
ENSDART00000087726
insulin-like growth factor 2 mRNA binding protein 1
chr12_-_23320266 0.55 ENSDART00000181711
membrane protein, palmitoylated 7a (MAGUK p55 subfamily member 7)
chr6_+_27667359 0.55 ENSDART00000159624
ENSDART00000049177
RAB6B, member RAS oncogene family a
chr20_+_30702531 0.55 ENSDART00000062525
acyl-Coenzyme A binding domain containing 3
chr15_-_8856785 0.55 ENSDART00000192816
RAB4B, member RAS oncogene family
chr20_-_18789543 0.55 ENSDART00000182240
cerebral cavernous malformation 2
chr23_+_1276006 0.55 ENSDART00000162294
utrophin
chr15_+_21707900 0.55 ENSDART00000141948
zgc:162339
chr10_-_35613752 0.54 ENSDART00000158537
SMG6 nonsense mediated mRNA decay factor
chr1_+_41478345 0.54 ENSDART00000134626
docking protein 1a
chr16_-_41488023 0.54 ENSDART00000169312
CKLF-like MARVEL transmembrane domain containing 6
chr6_-_3924543 0.54 ENSDART00000170584
tousled-like kinase 1b
chr10_-_20588787 0.54 ENSDART00000138045
ENSDART00000181885
ENSDART00000091115
nuclear receptor binding SET domain protein 3

Network of associatons between targets according to the STRING database.

First level regulatory network of znf384l

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0000212 meiotic spindle organization(GO:0000212)
0.5 2.3 GO:0000741 karyogamy(GO:0000741) pronuclear fusion(GO:0007344)
0.4 1.2 GO:0045002 double-strand break repair via single-strand annealing(GO:0045002)
0.4 1.1 GO:0060623 regulation of chromosome condensation(GO:0060623)
0.3 0.9 GO:0009211 pyrimidine deoxyribonucleoside triphosphate metabolic process(GO:0009211)
0.3 1.2 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.3 0.9 GO:1901890 positive regulation of cell junction assembly(GO:1901890)
0.3 1.2 GO:1904667 negative regulation of ligase activity(GO:0051352) negative regulation of ubiquitin-protein transferase activity(GO:0051444) negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.3 0.8 GO:0002926 tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridine biosynthesis.(GO:0002926)
0.3 0.8 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
0.3 1.0 GO:0051645 Golgi localization(GO:0051645)
0.2 1.7 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.2 0.7 GO:1901052 sarcosine metabolic process(GO:1901052)
0.2 1.1 GO:0039689 viral genome replication(GO:0019079) negative stranded viral RNA replication(GO:0039689) viral RNA genome replication(GO:0039694) RNA replication(GO:0039703) multi-organism biosynthetic process(GO:0044034)
0.2 0.9 GO:0034729 histone H3-K79 methylation(GO:0034729) regulation of transcription regulatory region DNA binding(GO:2000677)
0.2 1.1 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.2 1.0 GO:0051591 negative regulation of neurotransmitter secretion(GO:0046929) response to cAMP(GO:0051591) cellular response to cAMP(GO:0071320) negative regulation of synaptic vesicle transport(GO:1902804) negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.2 0.8 GO:0010825 positive regulation of centrosome duplication(GO:0010825)
0.2 1.2 GO:0060251 regulation of glial cell proliferation(GO:0060251)
0.2 0.6 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.2 0.8 GO:1900363 regulation of mRNA polyadenylation(GO:1900363)
0.2 0.5 GO:0051973 positive regulation of telomerase activity(GO:0051973)
0.2 0.7 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.1 1.5 GO:0000002 mitochondrial genome maintenance(GO:0000002)
0.1 0.7 GO:0051103 DNA ligation(GO:0006266) DNA ligation involved in DNA repair(GO:0051103)
0.1 1.3 GO:0009446 putrescine biosynthetic process(GO:0009446)
0.1 0.4 GO:0000390 spliceosomal complex disassembly(GO:0000390)
0.1 1.7 GO:0090309 methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.1 0.7 GO:1901910 diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.1 0.5 GO:2000058 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787) regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000058)
0.1 0.5 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.1 1.2 GO:0001709 cell fate determination(GO:0001709)
0.1 0.6 GO:0046490 isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate metabolic process(GO:0046490)
0.1 0.8 GO:1903846 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.1 0.2 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.1 0.5 GO:2000389 neutrophil extravasation(GO:0072672) regulation of neutrophil extravasation(GO:2000389) positive regulation of neutrophil extravasation(GO:2000391)
0.1 0.9 GO:0006465 signal peptide processing(GO:0006465)
0.1 0.9 GO:2000273 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) positive regulation of receptor activity(GO:2000273)
0.1 1.1 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.1 0.8 GO:0031113 regulation of microtubule polymerization(GO:0031113)
0.1 0.5 GO:0003173 ventriculo bulbo valve development(GO:0003173)
0.1 0.3 GO:0019408 dolichol biosynthetic process(GO:0019408)
0.1 0.5 GO:0030576 nuclear body organization(GO:0030575) Cajal body organization(GO:0030576) protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) protein localization to nucleoplasm(GO:1990173)
0.1 0.5 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.1 0.9 GO:0071816 tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.1 0.7 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.1 0.8 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.1 0.4 GO:0045041 protein import into mitochondrial intermembrane space(GO:0045041)
0.1 0.5 GO:0070734 histone H3-K27 methylation(GO:0070734)
0.1 0.3 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.1 1.0 GO:1901970 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of chromosome segregation(GO:0051984) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.1 0.2 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.1 0.4 GO:0070587 regulation of cell-cell adhesion involved in gastrulation(GO:0070587)
0.1 0.4 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.1 0.2 GO:0039531 RIG-I signaling pathway(GO:0039529) regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway(GO:0039531) regulation of RIG-I signaling pathway(GO:0039535)
0.1 0.2 GO:1904478 regulation of intestinal absorption(GO:1904478) regulation of intestinal lipid absorption(GO:1904729)
0.1 0.6 GO:1901224 positive regulation of NIK/NF-kappaB signaling(GO:1901224)
0.1 1.1 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.1 0.3 GO:0021856 pallium development(GO:0021543) cerebral cortex cell migration(GO:0021795) cerebral cortex tangential migration(GO:0021800) cerebral cortex tangential migration using cell-axon interactions(GO:0021824) substrate-dependent cerebral cortex tangential migration(GO:0021825) gonadotrophin-releasing hormone neuronal migration to the hypothalamus(GO:0021828) hypothalamic tangential migration using cell-axon interactions(GO:0021856) cerebral cortex development(GO:0021987)
0.1 0.5 GO:0090497 mesenchymal cell migration(GO:0090497)
0.1 1.2 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1 2.0 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.1 0.4 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.1 0.5 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.1 0.8 GO:0006689 ganglioside catabolic process(GO:0006689)
0.1 1.0 GO:0007339 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.1 0.8 GO:0009791 post-embryonic development(GO:0009791)
0.1 1.5 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.1 1.3 GO:0034626 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 1.4 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.1 0.7 GO:0050714 positive regulation of protein secretion(GO:0050714)
0.1 0.7 GO:2000054 negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.1 0.9 GO:0045022 early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.1 0.2 GO:0071514 genetic imprinting(GO:0071514)
0.1 0.2 GO:0003322 pancreatic A cell development(GO:0003322)
0.1 0.5 GO:0003160 endocardium morphogenesis(GO:0003160)
0.1 0.2 GO:0080182 histone H3-K4 trimethylation(GO:0080182) histone H3-K36 dimethylation(GO:0097676)
0.1 0.7 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.1 1.4 GO:0036297 interstrand cross-link repair(GO:0036297)
0.1 0.3 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.9 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.0 0.3 GO:0070073 regulation of melanocyte differentiation(GO:0045634) clustering of voltage-gated calcium channels(GO:0070073)
0.0 0.2 GO:0048103 neuronal stem cell division(GO:0036445) somatic stem cell division(GO:0048103)
0.0 0.7 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.5 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 0.2 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.0 0.6 GO:0006265 DNA topological change(GO:0006265)
0.0 0.3 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 0.3 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.2 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.0 1.9 GO:0016575 histone deacetylation(GO:0016575)
0.0 0.4 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.0 0.5 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.0 0.3 GO:0006478 protein sulfation(GO:0006477) peptidyl-tyrosine sulfation(GO:0006478)
0.0 0.4 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0 0.2 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.0 0.2 GO:0048680 positive regulation of axon regeneration(GO:0048680) positive regulation of neuron projection regeneration(GO:0070572)
0.0 0.2 GO:0045048 protein insertion into ER membrane(GO:0045048)
0.0 0.8 GO:0050684 regulation of mRNA processing(GO:0050684)
0.0 0.6 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.9 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
0.0 0.3 GO:0019883 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 0.3 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.0 0.5 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 1.2 GO:0007338 single fertilization(GO:0007338)
0.0 0.5 GO:0046855 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855) inositol phosphate catabolic process(GO:0071545)
0.0 0.1 GO:0006535 cysteine biosynthetic process from serine(GO:0006535) hydrogen sulfide biosynthetic process(GO:0070814)
0.0 2.6 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.0 0.2 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 1.5 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 0.2 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.4 GO:0045580 regulation of T cell differentiation(GO:0045580)
0.0 0.1 GO:1904184 regulation of pyruvate dehydrogenase activity(GO:1904182) positive regulation of pyruvate dehydrogenase activity(GO:1904184)
0.0 0.3 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 0.6 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 0.2 GO:0044090 positive regulation of vacuole organization(GO:0044090)
0.0 0.8 GO:0071427 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0 0.3 GO:0034453 microtubule anchoring(GO:0034453)
0.0 0.8 GO:0032482 Rab protein signal transduction(GO:0032482)
0.0 0.5 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.2 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.8 GO:0042632 cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
0.0 0.2 GO:1902038 positive regulation of hematopoietic stem cell differentiation(GO:1902038)
0.0 0.9 GO:0055088 lipid homeostasis(GO:0055088)
0.0 0.5 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.0 0.1 GO:0042148 strand invasion(GO:0042148)
0.0 0.2 GO:1990504 dense core granule exocytosis(GO:1990504)
0.0 0.0 GO:0050996 positive regulation of lipid catabolic process(GO:0050996)
0.0 0.4 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.3 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 0.7 GO:0009950 dorsal/ventral axis specification(GO:0009950)
0.0 0.2 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.3 GO:0003159 morphogenesis of an endothelium(GO:0003159) endothelial tube morphogenesis(GO:0061154) blood vessel lumenization(GO:0072554)
0.0 0.8 GO:0046579 positive regulation of Ras protein signal transduction(GO:0046579) positive regulation of small GTPase mediated signal transduction(GO:0051057)
0.0 0.5 GO:0051492 regulation of stress fiber assembly(GO:0051492)
0.0 0.3 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.2 GO:0046037 GMP biosynthetic process(GO:0006177) GMP metabolic process(GO:0046037)
0.0 0.1 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.1 GO:0046379 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.0 0.1 GO:0006004 fucose metabolic process(GO:0006004)
0.0 1.5 GO:0030837 negative regulation of actin filament polymerization(GO:0030837) negative regulation of protein polymerization(GO:0032272)
0.0 0.6 GO:2001243 negative regulation of intrinsic apoptotic signaling pathway(GO:2001243)
0.0 0.3 GO:0015693 magnesium ion transport(GO:0015693)
0.0 1.1 GO:0042493 response to drug(GO:0042493)
0.0 0.7 GO:0051028 mRNA transport(GO:0051028)
0.0 0.2 GO:0009204 deoxyribonucleoside triphosphate catabolic process(GO:0009204)
0.0 0.2 GO:0043550 regulation of lipid kinase activity(GO:0043550) regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.0 0.4 GO:0006491 N-glycan processing(GO:0006491)
0.0 1.5 GO:0007030 Golgi organization(GO:0007030)
0.0 4.9 GO:0000377 RNA splicing, via transesterification reactions(GO:0000375) RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.0 1.1 GO:0051402 neuron apoptotic process(GO:0051402)
0.0 0.6 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 1.2 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 1.3 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 0.7 GO:0045104 intermediate filament-based process(GO:0045103) intermediate filament cytoskeleton organization(GO:0045104)
0.0 0.1 GO:0055107 Golgi to secretory granule transport(GO:0055107)
0.0 0.6 GO:0071711 basement membrane organization(GO:0071711)
0.0 0.1 GO:1902024 L-histidine transmembrane transport(GO:0089709) L-histidine transport(GO:1902024)
0.0 0.8 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.1 GO:0031282 regulation of cGMP metabolic process(GO:0030823) positive regulation of cGMP metabolic process(GO:0030825) regulation of cGMP biosynthetic process(GO:0030826) positive regulation of cGMP biosynthetic process(GO:0030828) regulation of guanylate cyclase activity(GO:0031282) positive regulation of guanylate cyclase activity(GO:0031284)
0.0 0.4 GO:0031647 regulation of protein stability(GO:0031647)
0.0 0.2 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.0 0.2 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.0 0.6 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 0.1 GO:0007020 microtubule nucleation(GO:0007020)
0.0 0.3 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.3 GO:0002097 tRNA wobble base modification(GO:0002097)
0.0 0.2 GO:0005979 regulation of glycogen biosynthetic process(GO:0005979) regulation of glucan biosynthetic process(GO:0010962)
0.0 0.7 GO:0006606 protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744) single-organism nuclear import(GO:1902593)
0.0 0.1 GO:0040019 positive regulation of embryonic development(GO:0040019)
0.0 0.7 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.4 GO:0048013 negative regulation of Ras protein signal transduction(GO:0046580) ephrin receptor signaling pathway(GO:0048013)
0.0 0.0 GO:0048913 anterior lateral line nerve glial cell differentiation(GO:0048913) myelination of anterior lateral line nerve axons(GO:0048914) anterior lateral line nerve glial cell development(GO:0048939) anterior lateral line nerve glial cell morphogenesis involved in differentiation(GO:0048940)
0.0 0.2 GO:0009408 response to heat(GO:0009408)
0.0 0.6 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.7 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)
0.0 0.2 GO:0051482 negative regulation of cytosolic calcium ion concentration(GO:0051481) positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482) negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.0 GO:1903173 fatty alcohol metabolic process(GO:1903173)
0.0 0.6 GO:0002062 chondrocyte differentiation(GO:0002062)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0031251 PAN complex(GO:0031251)
0.3 2.0 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.3 1.5 GO:0032807 DNA ligase IV complex(GO:0032807)
0.3 0.8 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.2 0.9 GO:0098553 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.2 0.9 GO:0016600 flotillin complex(GO:0016600)
0.2 0.6 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.2 0.7 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.1 0.9 GO:0070695 FHF complex(GO:0070695)
0.1 0.5 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.1 1.2 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.1 0.9 GO:0001650 fibrillar center(GO:0001650)
0.1 1.5 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.1 0.7 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 0.8 GO:0071818 BAT3 complex(GO:0071818)
0.1 0.5 GO:0034448 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 0.7 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1 0.3 GO:0010369 chromocenter(GO:0010369)
0.1 0.6 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.1 1.2 GO:0048179 activin receptor complex(GO:0048179)
0.1 1.0 GO:0030126 COPI vesicle coat(GO:0030126)
0.1 0.8 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 0.8 GO:0036449 microtubule minus-end(GO:0036449)
0.1 0.7 GO:0031526 brush border membrane(GO:0031526)
0.1 0.3 GO:1904423 dehydrodolichyl diphosphate synthase complex(GO:1904423)
0.1 0.5 GO:0000439 core TFIIH complex(GO:0000439)
0.1 0.3 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.1 0.2 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.1 0.6 GO:0005688 U6 snRNP(GO:0005688)
0.1 0.6 GO:0045095 keratin filament(GO:0045095)
0.1 0.8 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 0.5 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.1 1.1 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.1 0.2 GO:0042575 DNA polymerase complex(GO:0042575)
0.1 1.1 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 2.1 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.4 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.3 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.0 0.9 GO:0070822 Sin3-type complex(GO:0070822)
0.0 0.2 GO:0070209 ASTRA complex(GO:0070209)
0.0 0.4 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 1.1 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 0.1 GO:0008274 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0 1.0 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.4 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.5 GO:0015030 Cajal body(GO:0015030)
0.0 0.6 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.3 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.8 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 1.0 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.7 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.4 GO:0045180 basal cortex(GO:0045180)
0.0 1.5 GO:0005657 replication fork(GO:0005657)
0.0 1.9 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.5 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.4 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.3 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.9 GO:0016605 PML body(GO:0016605)
0.0 1.9 GO:0005814 centriole(GO:0005814)
0.0 0.2 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 1.2 GO:0032432 actin filament bundle(GO:0032432)
0.0 2.3 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.6 GO:0031970 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 0.1 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.5 GO:0030686 90S preribosome(GO:0030686)
0.0 0.0 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) anchored component of the cytoplasmic side of the plasma membrane(GO:0098753)
0.0 1.4 GO:0005681 spliceosomal complex(GO:0005681)
0.0 0.3 GO:0005605 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.0 1.8 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.2 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.7 GO:0031902 late endosome membrane(GO:0031902)
0.0 0.6 GO:0016592 mediator complex(GO:0016592)
0.0 0.2 GO:0032420 stereocilium(GO:0032420)
0.0 0.7 GO:0030173 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.3 0.9 GO:0009041 uridylate kinase activity(GO:0009041)
0.3 2.6 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.2 1.7 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.2 0.7 GO:0008022 protein C-terminus binding(GO:0008022)
0.2 0.7 GO:0003909 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.2 0.9 GO:0031151 histone methyltransferase activity (H3-K79 specific)(GO:0031151)
0.2 0.7 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.2 1.0 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.2 0.8 GO:0033204 ribonuclease P RNA binding(GO:0033204)
0.2 0.6 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.2 1.2 GO:0016361 activin receptor activity, type I(GO:0016361)
0.2 0.6 GO:0015315 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.2 1.4 GO:0017070 U6 snRNA binding(GO:0017070)
0.2 0.5 GO:0008517 folic acid transporter activity(GO:0008517)
0.2 0.7 GO:0046997 oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.2 2.1 GO:0043028 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.1 0.6 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.1 0.4 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.1 0.7 GO:0034431 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.1 0.8 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.1 0.6 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.1 0.9 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 0.3 GO:0072590 N-acetyl-L-aspartate-L-glutamate ligase activity(GO:0072590) citrate-L-glutamate ligase activity(GO:0072591)
0.1 0.9 GO:0046625 sphingolipid binding(GO:0046625) ceramide binding(GO:0097001)
0.1 0.5 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.1 1.6 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.1 0.5 GO:0042809 vitamin D receptor binding(GO:0042809)
0.1 0.5 GO:0032183 SUMO binding(GO:0032183)
0.1 0.3 GO:0052717 tRNA-specific adenosine-34 deaminase activity(GO:0052717)
0.1 0.8 GO:0035925 AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 1.1 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.1 0.5 GO:0070034 telomerase RNA binding(GO:0070034)
0.1 0.3 GO:0001096 TFIIF-class transcription factor binding(GO:0001096)
0.1 0.3 GO:0045547 dehydrodolichyl diphosphate synthase activity(GO:0045547)
0.1 1.1 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 0.3 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.1 1.2 GO:0002039 p53 binding(GO:0002039)
0.1 0.6 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.1 0.2 GO:0051059 NF-kappaB binding(GO:0051059)
0.1 1.0 GO:0032190 acrosin binding(GO:0032190)
0.1 1.4 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.1 0.4 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.1 1.3 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 0.3 GO:0001223 transcription coactivator binding(GO:0001223)
0.1 0.5 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.1 0.8 GO:0070628 proteasome binding(GO:0070628)
0.0 0.6 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 1.2 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 1.0 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.2 GO:0008169 C-methyltransferase activity(GO:0008169)
0.0 1.0 GO:0008143 poly(A) binding(GO:0008143)
0.0 1.0 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.8 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 1.2 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.4 GO:0015924 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0 0.2 GO:0038131 neuregulin receptor activity(GO:0038131) neuregulin binding(GO:0038132)
0.0 0.9 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.1 GO:0015928 alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928)
0.0 0.6 GO:0031386 protein tag(GO:0031386)
0.0 0.7 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.3 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.0 0.2 GO:0016415 octanoyltransferase activity(GO:0016415)
0.0 0.2 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.0 0.2 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.0 0.2 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 0.1 GO:0000150 recombinase activity(GO:0000150)
0.0 0.8 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.5 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828)
0.0 0.4 GO:0070740 protein-glutamic acid ligase activity(GO:0070739) tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.4 GO:0016251 obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.0 1.0 GO:0019003 GDP binding(GO:0019003)
0.0 0.1 GO:0004122 cystathionine beta-synthase activity(GO:0004122)
0.0 0.1 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 0.3 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.0 1.2 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.6 GO:0015299 solute:proton antiporter activity(GO:0015299)
0.0 0.2 GO:0005522 profilin binding(GO:0005522)
0.0 1.0 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.7 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.9 GO:0004629 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 0.6 GO:0016876 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 0.7 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.8 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.1 GO:0016920 pyroglutamyl-peptidase activity(GO:0016920)
0.0 0.3 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.6 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.5 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 1.3 GO:0030170 pyridoxal phosphate binding(GO:0030170)
0.0 0.2 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.0 0.2 GO:0043035 chromatin insulator sequence binding(GO:0043035)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.7 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.1 GO:0016436 rRNA (uridine) methyltransferase activity(GO:0016436)
0.0 0.8 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 1.2 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.4 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.2 GO:2001069 glycogen binding(GO:2001069)
0.0 0.3 GO:0008252 nucleotidase activity(GO:0008252)
0.0 1.1 GO:0043566 structure-specific DNA binding(GO:0043566)
0.0 0.2 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.0 0.2 GO:0019211 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.0 0.1 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 0.3 GO:0005112 Notch binding(GO:0005112)
0.0 0.1 GO:0030620 U2 snRNA binding(GO:0030620)
0.0 0.2 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.3 GO:0071617 lysophospholipid acyltransferase activity(GO:0071617)
0.0 0.7 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.6 GO:0000146 microfilament motor activity(GO:0000146)
0.0 0.2 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.4 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.4 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.2 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.0 GO:0019797 procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.0 0.6 GO:0005178 integrin binding(GO:0005178)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.5 PID AURORA B PATHWAY Aurora B signaling
0.1 1.4 PID RHOA PATHWAY RhoA signaling pathway
0.1 0.5 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1 0.6 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.8 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 0.7 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.4 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.8 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 2.4 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.5 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 1.5 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.7 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 1.0 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.7 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.8 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 1.1 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 1.3 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 1.2 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.6 PID ATM PATHWAY ATM pathway
0.0 0.7 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 0.5 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.3 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.2 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.6 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.4 PID MYC PATHWAY C-MYC pathway
0.0 1.0 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.6 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.2 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.5 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.7 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 2.1 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.1 PID CDC42 PATHWAY CDC42 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 2.4 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.1 2.0 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1 0.4 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.1 0.3 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.1 1.1 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 0.7 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 0.9 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 0.7 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 1.0 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.9 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 1.2 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.4 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 1.9 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.6 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.8 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.6 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 1.2 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.6 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.5 REACTOME FORMATION OF THE HIV1 EARLY ELONGATION COMPLEX Genes involved in Formation of the HIV-1 Early Elongation Complex
0.0 0.2 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 1.0 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.6 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.0 0.6 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.4 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.2 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 1.3 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.7 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.5 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.3 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 1.7 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 1.3 REACTOME DIABETES PATHWAYS Genes involved in Diabetes pathways
0.0 0.6 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.4 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.1 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0 0.3 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.1 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.2 REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER Genes involved in Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
0.0 0.3 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.7 REACTOME REGULATION OF APOPTOSIS Genes involved in Regulation of Apoptosis
0.0 0.2 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.3 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.1 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.5 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation