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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for znf740b

Z-value: 1.04

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Transcription factors associated with znf740b

Gene Symbol Gene ID Gene Info
znf740b
ENSDARG00000061174 zinc finger protein 740b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
znf740bdr11_v1_chr23_-_36418059_364180590.701.2e-03Click!

Activity profile of znf740b motif

Sorted Z-values of znf740b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr25_+_1732838 4.39 ENSDART00000159555
ENSDART00000168161
FBLN1
fibulin 1
chr2_+_22694382 4.10 ENSDART00000139196
kif1ab
kinesin family member 1Ab
chr3_-_16289826 3.52 ENSDART00000131972
bckdhbl
branched chain keto acid dehydrogenase E1, beta polypeptide, like
chr2_-_44183613 3.13 ENSDART00000079596
cadm3
cell adhesion molecule 3
chr17_-_4395373 3.07 ENSDART00000015923
klhl10a
kelch-like family member 10a
chr3_+_62126981 2.95 ENSDART00000060527
drc3
dynein regulatory complex subunit 3
chr14_-_9522364 2.92 ENSDART00000054689
atoh8
atonal bHLH transcription factor 8
chr2_-_44183451 2.89 ENSDART00000111246
cadm3
cell adhesion molecule 3
chr10_-_5857548 2.83 ENSDART00000166933
si:ch211-281k19.2
si:ch211-281k19.2
chr21_-_43117327 2.74 ENSDART00000122352
p4ha2
procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide 2
chr16_+_10963602 2.59 ENSDART00000141032
pou2f2a
POU class 2 homeobox 2a
chr2_-_24907741 2.45 ENSDART00000155013
si:dkey-149i17.11
si:dkey-149i17.11
chr18_-_41232297 2.37 ENSDART00000036928
fbxo36a
F-box protein 36a
chr23_-_524780 2.34 ENSDART00000055139
col9a3
collagen, type IX, alpha 3
chr6_+_26314464 2.32 ENSDART00000115392
dzip1l
DAZ interacting zinc finger protein 1-like
chr15_-_5742531 2.29 ENSDART00000045985
phkg1a
phosphorylase kinase, gamma 1a (muscle)
chr5_-_68022631 2.22 ENSDART00000143199
wasf3a
WAS protein family, member 3a
chr16_+_10918252 2.20 ENSDART00000172949
pou2f2a
POU class 2 homeobox 2a
chr10_+_6613279 2.16 ENSDART00000149643
si:ch211-57m13.1
si:ch211-57m13.1
chr7_-_10606 2.01 ENSDART00000192650
ENSDART00000186761
FO704772.2

chr25_+_150570 2.00 ENSDART00000170892
adam10b
ADAM metallopeptidase domain 10b
chr22_-_15957041 2.00 ENSDART00000149236
ENSDART00000187500
ENSDART00000176304
ENSDART00000080047
ENSDART00000190068
eps15l1a
epidermal growth factor receptor pathway substrate 15-like 1a
chr20_+_26538137 1.99 ENSDART00000045397
stx11b.1
syntaxin 11b, tandem duplicate 1
chr8_-_23578660 1.97 ENSDART00000039080
wasb
Wiskott-Aldrich syndrome (eczema-thrombocytopenia) b
chr20_-_7080427 1.93 ENSDART00000140166
ENSDART00000023677
si:ch211-121a2.2
si:ch211-121a2.2
chr20_+_25340814 1.88 ENSDART00000063028
ctgfa
connective tissue growth factor a
chr19_-_6873107 1.87 ENSDART00000124440
CABZ01029822.1

chr11_-_3334248 1.83 ENSDART00000154314
ENSDART00000121861
prph
peripherin
chr3_-_1190132 1.79 ENSDART00000149709
smdt1a
single-pass membrane protein with aspartate-rich tail 1a
chr25_-_18470695 1.78 ENSDART00000034377
cpa5
carboxypeptidase A5
chr1_-_52498146 1.78 ENSDART00000122217
acy3.2
aspartoacylase (aminocyclase) 3, tandem duplicate 2
chr21_+_7823146 1.75 ENSDART00000030579
crhbp
corticotropin releasing hormone binding protein
chr10_+_8968203 1.74 ENSDART00000110443
ENSDART00000080772
fstb
follistatin b
chr22_+_35068046 1.74 ENSDART00000161660
ENSDART00000169573
si:ch73-173h19.3
si:ch73-173h19.3
chr22_+_24157807 1.73 ENSDART00000159165
b3galt2
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
chr4_-_68563862 1.72 ENSDART00000182970
BX548011.2

chr5_-_16351306 1.71 ENSDART00000168643
CABZ01088700.1

chr24_+_42131564 1.65 ENSDART00000153854
wwp1
WW domain containing E3 ubiquitin protein ligase 1
chr2_-_26527730 1.62 ENSDART00000138693
si:ch211-106k21.5
si:ch211-106k21.5
chr1_-_38709551 1.55 ENSDART00000128794
gpm6ab
glycoprotein M6Ab
chr24_-_28243186 1.54 ENSDART00000105691
cox4i1l
cytochrome c oxidase subunit IV isoform 1, like
chr10_+_10210455 1.54 ENSDART00000144214
sh2d3ca
SH2 domain containing 3Ca
chr13_-_45523026 1.53 ENSDART00000020663
rhd
Rh blood group, D antigen
chr18_+_21122818 1.52 ENSDART00000060015
ENSDART00000060184
chka
choline kinase alpha
chr7_-_35126374 1.51 ENSDART00000141211
hsd11b2
hydroxysteroid (11-beta) dehydrogenase 2
chr7_+_23495986 1.50 ENSDART00000190739
ENSDART00000115299
ENSDART00000101423
ENSDART00000142401
zgc:109889
zgc:109889
chr13_-_8776474 1.45 ENSDART00000122371
STPG4
si:ch211-93n23.7
chr2_-_23004286 1.44 ENSDART00000134664
ENSDART00000110373
ENSDART00000185833
ENSDART00000187235
znf414
mllt1b
zinc finger protein 414
MLLT1, super elongation complex subunit b
chr5_-_19052184 1.42 ENSDART00000133330
fam214b
family with sequence similarity 214, member B
chr3_-_59981162 1.42 ENSDART00000128790
cdr2l
cerebellar degeneration-related protein 2-like
chr24_+_42127983 1.42 ENSDART00000190157
ENSDART00000176032
ENSDART00000175790
wwp1
WW domain containing E3 ubiquitin protein ligase 1
chr24_-_21674950 1.42 ENSDART00000123216
ENSDART00000046211
lnx2a
ligand of numb-protein X 2a
chr15_-_5815006 1.42 ENSDART00000102459
rbp2a
retinol binding protein 2a, cellular
chr20_+_20672163 1.38 ENSDART00000027758
rtn1b
reticulon 1b
chr3_+_40809011 1.35 ENSDART00000033713
arpc1b
actin related protein 2/3 complex, subunit 1B
chr24_+_42132962 1.34 ENSDART00000187739
wwp1
WW domain containing E3 ubiquitin protein ligase 1
chr20_+_18740518 1.34 ENSDART00000142196
fam167ab
family with sequence similarity 167, member Ab
chr3_-_59981476 1.32 ENSDART00000035878
ENSDART00000124038
cdr2l
cerebellar degeneration-related protein 2-like
chr15_-_35246742 1.31 ENSDART00000131479
mff
mitochondrial fission factor
chr23_+_28494189 1.30 ENSDART00000146990
ENSDART00000006657
huwe1
HECT, UBA and WWE domain containing 1
chr19_-_10043142 1.30 ENSDART00000193016
grin2da
glutamate receptor, ionotropic, N-methyl D-aspartate 2D, a
chr2_+_24781026 1.29 ENSDART00000145692
pde4ca
phosphodiesterase 4C, cAMP-specific a
chr11_-_18705303 1.28 ENSDART00000059732
id1
inhibitor of DNA binding 1
chr12_+_2522642 1.24 ENSDART00000152567
frmpd2
FERM and PDZ domain containing 2
chr19_+_5315987 1.22 ENSDART00000145749
si:dkeyp-113d7.1
si:dkeyp-113d7.1
chr18_+_44649804 1.20 ENSDART00000059063
ehd2b
EH-domain containing 2b
chr23_-_19715557 1.17 ENSDART00000143764
rpl10
ribosomal protein L10
chr4_-_5597167 1.16 ENSDART00000132431
vegfab
vascular endothelial growth factor Ab
chr11_-_4298288 1.15 ENSDART00000188239
ENSDART00000183705
ENSDART00000187948
CT033790.1

chr10_-_31563049 1.13 ENSDART00000023575
robo3
roundabout, axon guidance receptor, homolog 3 (Drosophila)
chr25_-_1124851 1.11 ENSDART00000067558
spg11
spastic paraplegia 11
chr3_+_6469754 1.11 ENSDART00000185809
NUP85 (1 of many)
nucleoporin 85
chr1_-_52497834 1.06 ENSDART00000136469
ENSDART00000004233
acy3.2
aspartoacylase (aminocyclase) 3, tandem duplicate 2
chr14_-_32089117 1.05 ENSDART00000158014
si:ch211-69b22.5
si:ch211-69b22.5
chr1_-_52128425 1.04 ENSDART00000149939
rad23aa
RAD23 homolog A, nucleotide excision repair protein a
chr23_+_36083529 1.02 ENSDART00000053295
ENSDART00000130260
hoxc10a
homeobox C10a
chr2_+_33747509 1.02 ENSDART00000134187
si:dkey-31m5.5
si:dkey-31m5.5
chr2_-_16565690 1.01 ENSDART00000022549
atp1b3a
ATPase Na+/K+ transporting subunit beta 3a
chr2_-_23411368 1.01 ENSDART00000159495
si:ch73-129a22.11
si:ch73-129a22.11
chr10_+_2742499 1.00 ENSDART00000122847
grk5
G protein-coupled receptor kinase 5
chr4_-_26108053 1.00 ENSDART00000066951
si:ch211-244b2.4
si:ch211-244b2.4
chr5_-_3839285 0.99 ENSDART00000122292
mlxipl
MLX interacting protein like
chr5_+_6892195 0.97 ENSDART00000048201
gb:cr929477
expressed sequence CR929477
chr15_+_3284684 0.97 ENSDART00000179778
foxo1a
forkhead box O1 a
chr9_+_2522797 0.97 ENSDART00000186786
ENSDART00000147034
gpr155a
G protein-coupled receptor 155a
chr16_-_1709328 0.97 ENSDART00000168865
ascc3
activating signal cointegrator 1 complex subunit 3
chr8_+_8291492 0.94 ENSDART00000151314
srpk3
SRSF protein kinase 3
chr1_+_144284 0.93 ENSDART00000064061
prozb
protein Z, vitamin K-dependent plasma glycoprotein b
chr16_+_9713850 0.92 ENSDART00000164103
ecm1b
extracellular matrix protein 1b
chr2_-_23443189 0.91 ENSDART00000168894
si:ch211-14p21.4
si:ch211-14p21.4
chr11_-_497854 0.89 ENSDART00000104520
cnbpb
CCHC-type zinc finger, nucleic acid binding protein b
chr2_-_23479714 0.89 ENSDART00000167291
si:ch211-14p21.3
si:ch211-14p21.3
chr12_-_22540943 0.89 ENSDART00000172310
zbtb4
zinc finger and BTB domain containing 4
chr15_-_2734560 0.88 ENSDART00000153853
ppp5c
protein phosphatase 5, catalytic subunit
chr12_-_7854216 0.87 ENSDART00000149594
ank3b
ankyrin 3b
chr19_+_22085925 0.87 ENSDART00000185636
atp9b
ATPase phospholipid transporting 9B
chr17_+_3379673 0.87 ENSDART00000176354
sntg2
syntrophin, gamma 2
chr2_+_23790748 0.86 ENSDART00000041877
csrnp1a
cysteine-serine-rich nuclear protein 1a
chr13_-_31435137 0.86 ENSDART00000057441
rtn1a
reticulon 1a
chr15_+_3284416 0.85 ENSDART00000187665
ENSDART00000171723
foxo1a
forkhead box O1 a
chr24_+_41931585 0.85 ENSDART00000130310
epb41l3a
erythrocyte membrane protein band 4.1-like 3a
chr7_+_1449999 0.85 ENSDART00000173864
si:cabz01101003.1
si:cabz01101003.1
chr7_-_48665305 0.84 ENSDART00000190507
cdkn1ca
cyclin-dependent kinase inhibitor 1Ca
chr3_-_33417826 0.84 ENSDART00000084284
abi3a
ABI family, member 3a
chr4_-_26107841 0.83 ENSDART00000172012
si:ch211-244b2.4
si:ch211-244b2.4
chr25_-_11088839 0.82 ENSDART00000154748
sv2bb
synaptic vesicle glycoprotein 2Bb
chr15_-_30832897 0.82 ENSDART00000152330
msi2b
musashi RNA-binding protein 2b
chr12_-_47899497 0.80 ENSDART00000162219
QRFPR
pyroglutamylated RFamide peptide receptor
chr20_-_5052786 0.79 ENSDART00000138818
ENSDART00000181655
ENSDART00000164274
arid1b
AT rich interactive domain 1B (SWI1-like)
chr2_+_3595333 0.79 ENSDART00000041052
c1ql3b
complement component 1, q subcomponent-like 3b
chr23_-_35064785 0.78 ENSDART00000172240
BX294434.1

chr2_-_23515584 0.78 ENSDART00000170748
si:dkey-58b18.5
si:dkey-58b18.5
chr2_-_23577672 0.78 ENSDART00000132003
si:dkey-58b18.5
si:dkey-58b18.5
chr21_-_308852 0.76 ENSDART00000151613
lhfpl2a
LHFPL tetraspan subfamily member 2a
chr5_+_30699260 0.76 ENSDART00000012888
atp5l
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit g
chr9_+_13714379 0.75 ENSDART00000017593
ENSDART00000145503
tmem237a
transmembrane protein 237a
chr2_-_17694504 0.75 ENSDART00000133709
ptprfb
protein tyrosine phosphatase, receptor type, f, b
chr2_+_33052360 0.73 ENSDART00000134651
rnf220a
ring finger protein 220a
chr16_-_41439659 0.73 ENSDART00000191624
cpne4a
copine IVa
chr2_-_6051836 0.73 ENSDART00000092479
si:ch211-284b7.3
si:ch211-284b7.3
chr2_-_23546627 0.73 ENSDART00000141342
si:dkey-58b18.2
si:dkey-58b18.2
chr8_+_46010838 0.73 ENSDART00000143126
si:ch211-119d14.2
si:ch211-119d14.2
chr23_+_36101185 0.72 ENSDART00000103139
hoxc8a
homeobox C8a
chr20_-_51727860 0.72 ENSDART00000147044
brox
BRO1 domain and CAAX motif containing
chr7_+_46261199 0.72 ENSDART00000170390
ENSDART00000183227
znf536
zinc finger protein 536
chr17_+_53418445 0.72 ENSDART00000097631
slc9a1b
solute carrier family 9 member A1b
chr1_-_46632948 0.69 ENSDART00000148893
ENSDART00000053232
cdadc1
cytidine and dCMP deaminase domain containing 1
chr11_-_7078392 0.68 ENSDART00000112156
ENSDART00000188556
si:ch211-253b8.5
si:ch211-253b8.5
chr16_-_23800484 0.67 ENSDART00000139964
rps27.2
ribosomal protein S27, isoform 2
chr20_-_20610812 0.66 ENSDART00000181870
ppm1ab
protein phosphatase, Mg2+/Mn2+ dependent, 1Ab
chr21_+_25660613 0.65 ENSDART00000134017
si:dkey-17e16.15
si:dkey-17e16.15
chr5_-_40510397 0.63 ENSDART00000146237
ENSDART00000051065
fsta
follistatin a
chr2_+_33052169 0.63 ENSDART00000180008
rnf220a
ring finger protein 220a
chr2_+_7192966 0.63 ENSDART00000142735
si:ch211-13f8.1
si:ch211-13f8.1
chr8_+_23711842 0.62 ENSDART00000128783
ppardb
peroxisome proliferator-activated receptor delta b
chr25_-_37501371 0.62 ENSDART00000160498
CABZ01088346.1

chr23_+_5977965 0.61 ENSDART00000115403
ENSDART00000183147
NAV1 (1 of many)
neuron navigator 1
chr1_+_39553040 0.60 ENSDART00000137676
tenm3
teneurin transmembrane protein 3
chr2_+_36004381 0.59 ENSDART00000098706
lamc2
laminin, gamma 2
chr18_-_50845804 0.58 ENSDART00000158517
PDPR
si:cabz01113374.3
chr17_-_8976307 0.57 ENSDART00000092113
zranb1b
zinc finger, RAN-binding domain containing 1b
chr18_+_14529005 0.57 ENSDART00000186379
kcng4a
potassium voltage-gated channel, subfamily G, member 4a
chr18_-_7810214 0.56 ENSDART00000139505
ENSDART00000139188
shank3a
SH3 and multiple ankyrin repeat domains 3a
chr9_-_31278048 0.56 ENSDART00000022204
zic5
zic family member 5 (odd-paired homolog, Drosophila)
chr25_+_35502552 0.55 ENSDART00000189612
ENSDART00000058443
fibina
fin bud initiation factor a
chr7_-_55454406 0.54 ENSDART00000108646
piezo1
piezo-type mechanosensitive ion channel component 1
chr23_+_32499916 0.53 ENSDART00000134811
si:dkey-261h17.1
si:dkey-261h17.1
chr3_+_23703704 0.52 ENSDART00000024256
hoxb6a
homeobox B6a
chr24_-_28381404 0.52 ENSDART00000148406
prkag2a
protein kinase, AMP-activated, gamma 2 non-catalytic subunit a
chr18_+_17827149 0.51 ENSDART00000190237
ENSDART00000189345
ZNF423
si:ch211-216l23.1
chr18_+_35742838 0.51 ENSDART00000088504
ENSDART00000140386
rasgrp4
RAS guanyl releasing protein 4
chr2_+_16487443 0.51 ENSDART00000114980
CR377211.1

chr3_+_37824268 0.50 ENSDART00000137038
asic2
acid-sensing (proton-gated) ion channel 2
chr6_+_15373153 0.50 ENSDART00000155865
tmtops2a
teleost multiple tissue opsin 2a
chr8_+_25267903 0.50 ENSDART00000093090
ampd2b
adenosine monophosphate deaminase 2b
chr1_-_51474974 0.49 ENSDART00000152719
spred2a
sprouty-related, EVH1 domain containing 2a
chr3_+_52467879 0.49 ENSDART00000156039
adgre5a
adhesion G protein-coupled receptor E5a
chr15_+_2534740 0.48 ENSDART00000138469
cux1b
cut-like homeobox 1b
chr11_+_6650966 0.48 ENSDART00000131236
si:dkey-246j7.1
si:dkey-246j7.1
chr3_-_26204867 0.47 ENSDART00000103748
gdpd3a
glycerophosphodiester phosphodiesterase domain containing 3a
chr4_+_34417403 0.47 ENSDART00000186032
ENSDART00000167909
si:ch211-246b8.2
si:ch211-246b8.2
chr7_+_41314862 0.46 ENSDART00000185198
zgc:165532
zgc:165532
chr7_+_8361083 0.46 ENSDART00000102091
jac7
jacalin 7
chr2_+_54389750 0.46 ENSDART00000189236
rab12
RAB12, member RAS oncogene family
chr16_-_31435020 0.46 ENSDART00000138508
zgc:194210
zgc:194210
chr11_-_41130239 0.45 ENSDART00000173268
dnajc11b
DnaJ (Hsp40) homolog, subfamily C, member 11b
chr2_-_16217344 0.44 ENSDART00000152031
arhgef4
Rho guanine nucleotide exchange factor (GEF) 4
chr7_-_69636502 0.44 ENSDART00000126739
tspan5a
tetraspanin 5a
chr13_+_771403 0.44 ENSDART00000093166
nrxn1b
neurexin 1b
chr25_+_4750972 0.43 ENSDART00000168903
si:zfos-2372e4.1
si:zfos-2372e4.1
chr3_+_13440900 0.43 ENSDART00000143715
GNG14
si:dkey-117i10.1
chr21_+_30351256 0.41 ENSDART00000078341
foxi3a
forkhead box I3a
chr22_+_17261801 0.41 ENSDART00000192978
ENSDART00000193187
ENSDART00000179953
ENSDART00000134798
tdrd5
tudor domain containing 5
chr18_+_45990394 0.41 ENSDART00000024068
mmp23bb
matrix metallopeptidase 23bb
chr25_+_13191615 0.40 ENSDART00000168849
si:ch211-147m6.2
si:ch211-147m6.2
chr6_-_43677125 0.40 ENSDART00000150128
foxp1b
forkhead box P1b
chr21_-_11820379 0.39 ENSDART00000126640
RHOBTB3
si:dkey-6b12.5
chr9_-_39968820 0.39 ENSDART00000100311
IKZF2
si:zfos-1425h8.1
chr9_+_29585943 0.38 ENSDART00000185989
ENSDART00000115290
mcf2lb
mcf.2 cell line derived transforming sequence-like b
chr23_-_9864166 0.38 ENSDART00000124510
ENSDART00000187934
prkcbp1l
protein kinase C binding protein 1, like
chr7_+_36552725 0.38 ENSDART00000173682
chd9
chromodomain helicase DNA binding protein 9
chr20_-_25542183 0.38 ENSDART00000024350
cyp2ad2
cytochrome P450, family 2, subfamily AD, polypeptide 2
chr19_-_46957968 0.38 ENSDART00000043713
angpt1
angiopoietin 1
chr25_+_13191391 0.38 ENSDART00000109937
si:ch211-147m6.2
si:ch211-147m6.2
chr24_-_40860603 0.38 ENSDART00000188032
CU633479.7

chr15_-_40267485 0.37 ENSDART00000152253
kcnj13
potassium inwardly-rectifying channel, subfamily J, member 13
chr1_-_44638058 0.37 ENSDART00000081835
slc43a1b
solute carrier family 43 (amino acid system L transporter), member 1b
chr19_+_42983613 0.37 ENSDART00000033724
fabp3
fatty acid binding protein 3, muscle and heart
chr1_+_31112436 0.36 ENSDART00000075340
eef1a1b
eukaryotic translation elongation factor 1 alpha 1b
chr23_+_42434348 0.36 ENSDART00000161027
cyp2aa1
cytochrome P450, family 2, subfamily AA, polypeptide 1
chr13_+_23677949 0.36 ENSDART00000144215
pcnxl2
pecanex-like 2 (Drosophila)
chr3_-_31804481 0.36 ENSDART00000028270
gfap
glial fibrillary acidic protein
chr7_+_38249858 0.35 ENSDART00000150158
si:dkey-78a14.4
si:dkey-78a14.4
chr18_-_16181952 0.35 ENSDART00000157824
slc6a15
solute carrier family 6 (neutral amino acid transporter), member 15
chr10_-_43113731 0.35 ENSDART00000138099
tmem167a
transmembrane protein 167A
chr4_-_73572030 0.34 ENSDART00000121652
znf1015
zinc finger protein 1015
chr23_+_44049509 0.34 ENSDART00000102003
txk
TXK tyrosine kinase
chr17_+_52822422 0.33 ENSDART00000158273
ENSDART00000161414
meis2a
Meis homeobox 2a
chr7_+_61480296 0.33 ENSDART00000083255
adam19a
ADAM metallopeptidase domain 19a
chr11_-_40504170 0.32 ENSDART00000165394
si:dkeyp-61b2.1
si:dkeyp-61b2.1

Network of associatons between targets according to the STRING database.

First level regulatory network of znf740b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 2.9 GO:2001014 regulation of skeletal muscle cell differentiation(GO:2001014)
0.6 1.8 GO:0002792 negative regulation of peptide secretion(GO:0002792) negative regulation of peptide hormone secretion(GO:0090278)
0.4 1.2 GO:1990403 embryonic brain development(GO:1990403)
0.4 5.7 GO:0051127 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.3 0.9 GO:0060031 mediolateral intercalation(GO:0060031)
0.3 1.8 GO:0048745 smooth muscle tissue development(GO:0048745)
0.2 2.4 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.2 1.5 GO:0034650 cortisol metabolic process(GO:0034650)
0.2 1.5 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.2 0.9 GO:2000767 positive regulation of cytoplasmic translation(GO:2000767)
0.2 0.6 GO:0048014 Tie signaling pathway(GO:0048014)
0.2 1.4 GO:1904861 excitatory synapse assembly(GO:1904861)
0.1 0.6 GO:0070983 dendrite guidance(GO:0070983) regulation of homophilic cell adhesion(GO:1903385)
0.1 2.7 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471)
0.1 2.3 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.1 1.7 GO:0030311 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.1 0.8 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.1 1.0 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.1 1.5 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 1.2 GO:0060753 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.1 0.6 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.1 0.5 GO:0003173 ventriculo bulbo valve development(GO:0003173) epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.1 1.3 GO:0060079 excitatory postsynaptic potential(GO:0060079)
0.1 0.4 GO:0009957 epidermal cell fate specification(GO:0009957)
0.1 0.4 GO:0051876 pigment granule dispersal(GO:0051876)
0.1 0.3 GO:0015820 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.1 0.8 GO:0046546 development of primary male sexual characteristics(GO:0046546)
0.1 0.8 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.1 0.5 GO:0010799 regulation of peptidyl-threonine phosphorylation(GO:0010799) negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.1 1.1 GO:0016199 axon midline choice point recognition(GO:0016199)
0.1 0.6 GO:0033278 cell proliferation in midbrain(GO:0033278)
0.1 0.3 GO:0015677 copper ion import(GO:0015677)
0.1 0.7 GO:0098719 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 1.5 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.1 0.6 GO:0010887 negative regulation of cholesterol storage(GO:0010887)
0.1 2.0 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.1 0.3 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.1 1.3 GO:0002574 thrombocyte differentiation(GO:0002574)
0.1 5.9 GO:0045732 positive regulation of protein catabolic process(GO:0045732)
0.1 2.0 GO:0099500 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.1 1.1 GO:0006198 cAMP catabolic process(GO:0006198)
0.1 1.0 GO:0071436 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.1 0.3 GO:0010754 negative regulation of cGMP-mediated signaling(GO:0010754)
0.1 0.8 GO:0021988 olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988)
0.1 1.1 GO:0001966 thigmotaxis(GO:0001966)
0.0 2.3 GO:0009250 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 0.4 GO:0043046 DNA methylation involved in gamete generation(GO:0043046)
0.0 0.5 GO:0032264 IMP salvage(GO:0032264)
0.0 0.9 GO:0070167 regulation of bone mineralization(GO:0030500) regulation of biomineral tissue development(GO:0070167)
0.0 1.1 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.8 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.4 GO:0042407 cristae formation(GO:0042407)
0.0 0.7 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.7 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 1.3 GO:0045103 intermediate filament-based process(GO:0045103) intermediate filament cytoskeleton organization(GO:0045104)
0.0 0.3 GO:0042664 locus ceruleus development(GO:0021703) negative regulation of endodermal cell fate specification(GO:0042664)
0.0 0.2 GO:1902259 regulation of delayed rectifier potassium channel activity(GO:1902259)
0.0 1.1 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.5 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 0.2 GO:0007608 sensory perception of smell(GO:0007608)
0.0 1.0 GO:0042737 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.0 0.4 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 6.5 GO:0046777 protein autophosphorylation(GO:0046777)
0.0 0.2 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.0 0.3 GO:0006228 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.0 0.6 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 2.8 GO:0030705 cytoskeleton-dependent intracellular transport(GO:0030705)
0.0 0.1 GO:0050938 regulation of xanthophore differentiation(GO:0050938)
0.0 0.2 GO:0030816 activation of adenylate cyclase activity(GO:0007190) positive regulation of cAMP metabolic process(GO:0030816) positive regulation of cAMP biosynthetic process(GO:0030819) positive regulation of adenylate cyclase activity(GO:0045762)
0.0 0.5 GO:0032482 Rab protein signal transduction(GO:0032482)
0.0 0.5 GO:0044243 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.0 0.2 GO:0051452 vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452)
0.0 0.1 GO:0097090 presynaptic membrane organization(GO:0097090) postsynaptic membrane assembly(GO:0097104) presynaptic membrane assembly(GO:0097105)
0.0 0.2 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.0 0.2 GO:0060971 embryonic heart tube left/right pattern formation(GO:0060971)
0.0 0.6 GO:0006289 nucleotide-excision repair(GO:0006289)
0.0 0.3 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.3 GO:0001843 neural tube closure(GO:0001843)
0.0 0.6 GO:0043113 receptor clustering(GO:0043113)
0.0 0.9 GO:0007596 blood coagulation(GO:0007596)
0.0 2.0 GO:0016197 endosomal transport(GO:0016197)
0.0 0.1 GO:0032656 interleukin-13 production(GO:0032616) regulation of interleukin-13 production(GO:0032656)
0.0 0.3 GO:0051289 protein homotetramerization(GO:0051289)
0.0 0.6 GO:0000245 spliceosomal complex assembly(GO:0000245)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.7 GO:0031209 SCAR complex(GO:0031209)
0.2 2.3 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.1 1.8 GO:1990246 uniplex complex(GO:1990246)
0.1 0.4 GO:0033391 chromatoid body(GO:0033391)
0.1 1.3 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
0.1 1.5 GO:0044295 axonal growth cone(GO:0044295)
0.1 1.5 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 2.0 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.1 1.7 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.1 1.3 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 2.0 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 2.7 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.8 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.5 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.5 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.4 GO:0061617 MICOS complex(GO:0061617)
0.0 0.2 GO:0043514 interleukin-12 complex(GO:0043514) interleukin-23 complex(GO:0070743)
0.0 0.9 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 1.2 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 2.8 GO:0005871 kinesin complex(GO:0005871)
0.0 3.6 GO:0016607 nuclear speck(GO:0016607)
0.0 2.3 GO:0005814 centriole(GO:0005814)
0.0 3.7 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.8 GO:0035869 ciliary transition zone(GO:0035869)
0.0 0.2 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 1.2 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.7 GO:0022627 cytosolic ribosome(GO:0022626) cytosolic small ribosomal subunit(GO:0022627)
0.0 1.5 GO:0005884 actin filament(GO:0005884)
0.0 0.5 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.5 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.8 GO:0030027 lamellipodium(GO:0030027)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:1902945 metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902945)
0.6 1.7 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.5 2.3 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.4 3.7 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.3 1.2 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.3 2.8 GO:0004046 aminoacylase activity(GO:0004046)
0.2 2.7 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.2 3.5 GO:0033691 sialic acid binding(GO:0033691)
0.1 1.7 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.1 2.4 GO:0048185 activin binding(GO:0048185)
0.1 3.7 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 0.8 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 0.7 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 0.6 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.1 0.3 GO:0072571 ADP-D-ribose binding(GO:0072570) mono-ADP-D-ribose binding(GO:0072571)
0.1 1.2 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.1 0.3 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.1 1.0 GO:0070628 proteasome binding(GO:0070628)
0.1 0.3 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.1 1.8 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 0.7 GO:0015386 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.1 1.3 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.1 0.4 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.1 1.5 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 0.2 GO:2001070 starch binding(GO:2001070)
0.1 0.3 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.1 1.0 GO:0001671 ATPase activator activity(GO:0001671)
0.0 1.8 GO:0017046 peptide hormone binding(GO:0017046)
0.0 1.1 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.5 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.1 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.5 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.1 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 1.0 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 0.6 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.2 GO:0042164 interleukin-12 binding(GO:0019972) interleukin-12 alpha subunit binding(GO:0042164)
0.0 3.5 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 1.1 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.5 GO:0005080 protein kinase C binding(GO:0005080)
0.0 2.1 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.3 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.6 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.5 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 0.2 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 0.6 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 8.5 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 0.1 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.5 GO:0016208 AMP binding(GO:0016208)
0.0 2.3 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.5 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.9 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.2 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
0.0 0.2 GO:0051117 ATPase binding(GO:0051117)
0.0 0.9 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.9 GO:0008201 heparin binding(GO:0008201)
0.0 0.5 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.1 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.4 PID ERBB4 PATHWAY ErbB4 signaling events
0.1 1.3 PID IL3 PATHWAY IL3-mediated signaling events
0.1 1.0 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.1 2.3 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.6 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 1.7 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.2 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 4.7 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.3 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.5 PID RAS PATHWAY Regulation of Ras family activation
0.0 2.7 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.4 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.1 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 2.3 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 4.7 REACTOME SIGNALING BY ERBB4 Genes involved in Signaling by ERBB4
0.0 0.6 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.4 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.2 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.2 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.3 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.3 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 1.6 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events
0.0 1.0 REACTOME INTEGRATION OF ENERGY METABOLISM Genes involved in Integration of energy metabolism
0.0 0.8 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0 0.6 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 1.2 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation