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12D miR HR13_24

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Results for Zic3

Z-value: 0.76

Motif logo

Transcription factors associated with Zic3

Gene Symbol Gene ID Gene Info
ENSMUSG00000067860.5 zinc finger protein of the cerebellum 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Zic3mm10_v2_chrX_+_58030622_580306430.244.7e-01Click!

Activity profile of Zic3 motif

Sorted Z-values of Zic3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr13_-_29984219 1.08 ENSMUST00000146092.1
E2F transcription factor 3
chr12_+_3806513 0.71 ENSMUST00000172719.1
DNA methyltransferase 3A
chr17_+_86963279 0.55 ENSMUST00000139344.1
ras homolog gene family, member Q
chr7_-_80403315 0.48 ENSMUST00000147150.1
furin (paired basic amino acid cleaving enzyme)
chr3_-_92485886 0.47 ENSMUST00000054599.7
small proline-rich protein 1A
chr13_+_44729535 0.46 ENSMUST00000174068.1
jumonji, AT rich interactive domain 2
chr11_+_115900125 0.44 ENSMUST00000142089.1
ENSMUST00000131566.1
small integral membrane protein 5
chr1_+_92619881 0.40 ENSMUST00000081274.3
olfactory receptor 12
chr8_-_106136792 0.39 ENSMUST00000146940.1
epithelial splicing regulatory protein 2
chr9_-_110645328 0.38 ENSMUST00000149089.1
neurobeachin-like 2
chr3_+_134828993 0.37 ENSMUST00000029822.4
tachykinin receptor 3
chr14_+_121035194 0.34 ENSMUST00000135010.1
FERM, RhoGEF (Arhgef) and pleckstrin domain protein 1 (chondrocyte-derived)
chr15_-_58324161 0.34 ENSMUST00000022985.1
kelch-like 38
chr1_-_153186447 0.33 ENSMUST00000027753.6
laminin, gamma 2
chr7_+_127800604 0.32 ENSMUST00000046863.5
ENSMUST00000106272.1
ENSMUST00000139068.1
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
chr16_+_48842552 0.32 ENSMUST00000023329.4
resistin like alpha
chr9_-_123678873 0.31 ENSMUST00000040960.6
solute carrier family 6 (neurotransmitter transporter), member 20A
chr7_+_35802593 0.30 ENSMUST00000052454.2
RIKEN cDNA E130304I02 gene
chr1_+_193153107 0.30 ENSMUST00000076521.5
interferon regulatory factor 6
chr9_-_77544829 0.30 ENSMUST00000183734.1
leucine rich repeat containing 1
chr4_+_43631935 0.29 ENSMUST00000030191.8
natriuretic peptide receptor 2
chr1_+_187608755 0.29 ENSMUST00000127489.1
estrogen-related receptor gamma
chr10_+_80805233 0.29 ENSMUST00000036016.4
anti-Mullerian hormone
chr10_-_81472859 0.29 ENSMUST00000147524.1
ENSMUST00000119060.1
CUGBP, Elav-like family member 5
chr2_-_146511899 0.28 ENSMUST00000131824.1
Ral GTPase activating protein, alpha subunit 2 (catalytic)
chr2_-_92371039 0.28 ENSMUST00000068586.6
glycosyltransferase-like 1B
chr2_+_55437100 0.28 ENSMUST00000112633.2
ENSMUST00000112632.1
potassium inwardly-rectifying channel, subfamily J, member 3
chr9_-_29412204 0.28 ENSMUST00000115237.1
neurotrimin
chr16_-_91011029 0.28 ENSMUST00000130813.1
synaptojanin 1
chr17_-_83631892 0.27 ENSMUST00000051482.1
potassium voltage-gated channel, subfamily G, member 3
chr13_+_44730726 0.26 ENSMUST00000173704.1
ENSMUST00000044608.7
ENSMUST00000173367.1
jumonji, AT rich interactive domain 2
chr17_-_73710415 0.26 ENSMUST00000112591.2
ENSMUST00000024858.5
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14
chr2_-_92370968 0.26 ENSMUST00000176774.1
glycosyltransferase-like 1B
chr2_-_92370999 0.26 ENSMUST00000176810.1
ENSMUST00000090582.4
glycosyltransferase-like 1B
chr12_-_27342696 0.25 ENSMUST00000079063.5
SRY-box containing gene 11
chr2_-_170427828 0.25 ENSMUST00000013667.2
ENSMUST00000109152.2
ENSMUST00000068137.4
breast carcinoma amplified sequence 1
chr16_-_32810477 0.25 ENSMUST00000179384.2
predicted gene 933
chr2_-_54085542 0.25 ENSMUST00000100089.2
reprimo, TP53 dependent G2 arrest mediator candidate
chr19_+_5878622 0.24 ENSMUST00000136833.1
ENSMUST00000141362.1
solute carrier family 25, member 45
chr15_-_50890396 0.24 ENSMUST00000185183.1
trichorhinophalangeal syndrome I (human)
chr17_+_34187545 0.24 ENSMUST00000170086.1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr9_-_44721383 0.24 ENSMUST00000148929.1
ENSMUST00000123406.1
pleckstrin homology-like domain, family B, member 1
chr11_+_50237002 0.23 ENSMUST00000180443.1
predicted gene, 26542
chr17_-_32788284 0.23 ENSMUST00000159086.2
zinc finger protein 871
chr1_-_134955847 0.23 ENSMUST00000168381.1
protein phosphatase 1, regulatory (inhibitor) subunit 12B
chr11_+_97030130 0.22 ENSMUST00000153482.1
secernin 2
chr5_-_137212389 0.22 ENSMUST00000179412.1
RIKEN cDNA A630081J09 gene
chr8_+_94329192 0.22 ENSMUST00000034218.3
solute carrier family 12, member 3
chr19_-_6921753 0.22 ENSMUST00000173635.1
estrogen related receptor, alpha
chrX_-_61185558 0.21 ENSMUST00000166381.1
cerebellar degeneration related antigen 1
chr11_+_116280939 0.21 ENSMUST00000055872.2
galanin receptor 2
chr1_-_132139605 0.21 ENSMUST00000112362.2
cyclin-dependent kinase 18
chr5_+_107437908 0.21 ENSMUST00000094541.2
BTB (POZ) domain containing 8
chr6_+_48395652 0.20 ENSMUST00000077093.4
KRAB-A domain containing 1
chr8_-_25101734 0.20 ENSMUST00000098866.4
pleckstrin homology domain-containing, family A (phosphoinositide binding specific) member 2
chr2_+_18998332 0.20 ENSMUST00000028069.1
RIKEN cDNA 4930426L09 gene
chr11_+_4267095 0.20 ENSMUST00000040750.3
leukemia inhibitory factor
chr5_+_137288273 0.19 ENSMUST00000024099.4
ENSMUST00000085934.3
acetylcholinesterase
chr4_-_152131865 0.19 ENSMUST00000105653.1
espin
chr1_-_132139666 0.19 ENSMUST00000027697.5
cyclin-dependent kinase 18
chr9_-_123678782 0.19 ENSMUST00000170591.1
ENSMUST00000171647.1
solute carrier family 6 (neurotransmitter transporter), member 20A
chr7_-_17062384 0.18 ENSMUST00000153833.1
ENSMUST00000108492.2
hypoxia inducible factor 3, alpha subunit
chr6_+_7844806 0.18 ENSMUST00000040159.4
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1
chr14_-_30943275 0.18 ENSMUST00000006704.8
ENSMUST00000163118.1
inter-alpha trypsin inhibitor, heavy chain 1
chr15_-_76126538 0.18 ENSMUST00000054022.5
ENSMUST00000089654.3
cDNA sequence BC024139
chr2_+_31640037 0.18 ENSMUST00000113470.2
PR domain containing 12
chr1_-_133801031 0.18 ENSMUST00000143567.1
ATPase, Ca++ transporting, plasma membrane 4
chr13_-_24937585 0.18 ENSMUST00000037615.6
aldhehyde dehydrogenase family 5, subfamily A1
chr2_+_120629113 0.18 ENSMUST00000150912.1
ENSMUST00000180041.1
START domain containing 9
chr4_+_43059028 0.17 ENSMUST00000163653.1
ENSMUST00000107952.2
ENSMUST00000107953.2
unc-13 homolog B (C. elegans)
chr9_-_77544870 0.17 ENSMUST00000183873.1
leucine rich repeat containing 1
chr12_-_103773592 0.17 ENSMUST00000078869.5
serine (or cysteine) peptidase inhibitor, clade A, member 1D
chr9_-_49486209 0.17 ENSMUST00000055096.4
tetratricopeptide repeat domain 12
chr19_+_42045792 0.17 ENSMUST00000172244.1
ENSMUST00000081714.4
4-hydroxy-2-oxoglutarate aldolase 1
chr11_-_109472611 0.17 ENSMUST00000168740.1
solute carrier family 16 (monocarboxylic acid transporters), member 6
chr5_+_105732063 0.17 ENSMUST00000154807.1
leucine rich repeat containing 8D
chr7_+_30169861 0.17 ENSMUST00000085668.4
predicted gene 5113
chr4_+_154856200 0.16 ENSMUST00000050220.2
tetratricopeptide repeat domain 34
chr17_+_13526128 0.16 ENSMUST00000115649.2
sperm motility kinase 4A
chr18_+_37489465 0.16 ENSMUST00000055949.2
protocadherin beta 18
chr16_+_32735886 0.16 ENSMUST00000132475.1
ENSMUST00000096106.3
mucin 4
chr1_-_75232093 0.16 ENSMUST00000180101.1
RIKEN cDNA A630095N17 gene
chr9_+_108648720 0.16 ENSMUST00000098384.2
predicted gene 10621
chr9_-_29411736 0.16 ENSMUST00000115236.1
neurotrimin
chr1_+_91322075 0.16 ENSMUST00000088904.3
espin-like
chr6_+_48395586 0.16 ENSMUST00000114571.1
ENSMUST00000114572.3
ENSMUST00000031815.5
KRAB-A domain containing 1
chr1_-_74951651 0.15 ENSMUST00000164097.1
Indian hedgehog
chr14_+_41131777 0.15 ENSMUST00000022314.3
ENSMUST00000170719.1
surfactant associated protein A1
chr4_-_53159885 0.15 ENSMUST00000030010.3
ATP-binding cassette, sub-family A (ABC1), member 1
chr6_-_40544977 0.15 ENSMUST00000089490.2
olfactory receptor 461
chr2_-_39190687 0.15 ENSMUST00000142872.1
ENSMUST00000038874.5
suppressor of cancer cell invasion
chr15_-_76209056 0.15 ENSMUST00000071869.5
ENSMUST00000170915.1
plectin
chr5_+_105731755 0.15 ENSMUST00000127686.1
leucine rich repeat containing 8D
chr8_-_18950932 0.15 ENSMUST00000055503.5
ENSMUST00000095438.3
X Kell blood group precursor-related family, member 5
chr4_+_43632185 0.15 ENSMUST00000107874.2
natriuretic peptide receptor 2
chr16_-_85550417 0.15 ENSMUST00000175700.1
ENSMUST00000114174.2
cysteine and tyrosine-rich protein 1
chr5_-_107726017 0.15 ENSMUST00000159263.2
growth factor independent 1
chr5_-_134456227 0.14 ENSMUST00000111244.1
general transcription factor II I repeat domain-containing 1
chr9_-_32344237 0.14 ENSMUST00000034533.5
potassium inwardly-rectifying channel, subfamily J, member 5
chr11_-_65269984 0.14 ENSMUST00000108695.2
myocardin
chr1_-_132707304 0.14 ENSMUST00000043189.7
neurofascin
chrX_-_49788204 0.14 ENSMUST00000114893.1
immunoglobulin superfamily, member 1
chr2_+_71529085 0.14 ENSMUST00000152711.1
distal-less homeobox 1
chr8_-_122460666 0.14 ENSMUST00000006762.5
snail homolog 3 (Drosophila)
chr15_-_101370125 0.14 ENSMUST00000077196.4
keratin 80
chrY_-_1245753 0.13 ENSMUST00000154004.1
ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome
chr2_+_127008711 0.13 ENSMUST00000110394.1
ENSMUST00000002063.8
adaptor-related protein complex AP-4, epsilon 1
chr5_-_144026596 0.13 ENSMUST00000031622.6
ENSMUST00000110702.1
oncomodulin
chrX_-_167382747 0.13 ENSMUST00000026839.4
phosphoribosyl pyrophosphate synthetase 2
chr10_+_39732364 0.13 ENSMUST00000164763.1
REV3-like, catalytic subunit of DNA polymerase zeta RAD54 like (S. cerevisiae)
chrX_+_52791179 0.13 ENSMUST00000101588.1
coiled-coil domain containing 160
chr2_-_160327494 0.13 ENSMUST00000099127.2
predicted gene 826
chr4_+_57568144 0.12 ENSMUST00000102904.3
paralemmin 2
chr1_-_191907527 0.12 ENSMUST00000069573.5
RIKEN cDNA 1700034H15 gene
chr4_-_136956784 0.12 ENSMUST00000030420.8
Eph receptor A8
chr1_-_58586191 0.12 ENSMUST00000038372.7
ENSMUST00000097724.3
ENSMUST00000161000.1
ENSMUST00000161600.1
family with sequence similarity 126, member B
chr1_+_75507077 0.12 ENSMUST00000037330.4
inhibin alpha
chr10_+_18845071 0.12 ENSMUST00000019998.7
PERP, TP53 apoptosis effector
chr17_-_68004075 0.12 ENSMUST00000024840.5
Rho GTPase activating protein 28
chr10_+_81575306 0.12 ENSMUST00000146916.1
transducin-like enhancer of split 2, homolog of Drosophila E(spl)
chr2_+_169633517 0.12 ENSMUST00000109157.1
teashirt zinc finger family member 2
chr11_-_69549108 0.12 ENSMUST00000108659.1
dynein, axonemal, heavy chain 2
chr11_+_115899943 0.12 ENSMUST00000152171.1
small integral membrane protein 5
chr8_+_4243264 0.12 ENSMUST00000110996.1
mitogen-activated protein kinase kinase 7
chr2_-_24763047 0.12 ENSMUST00000100348.3
ENSMUST00000041342.5
ENSMUST00000114447.1
ENSMUST00000102939.2
ENSMUST00000070864.7
calcium channel, voltage-dependent, N type, alpha 1B subunit
chr15_-_76232554 0.12 ENSMUST00000166428.1
plectin
chr13_-_54687644 0.11 ENSMUST00000129881.1
ring finger protein 44
chr12_+_83763654 0.11 ENSMUST00000021646.5
papilin, proteoglycan-like sulfated glycoprotein
chr15_-_76232045 0.11 ENSMUST00000167754.1
plectin
chr5_+_30588078 0.11 ENSMUST00000066295.2
potassium channel, subfamily K, member 3
chr8_-_126475062 0.11 ENSMUST00000170518.1
predicted gene, 17296
chr11_-_118248489 0.11 ENSMUST00000100181.4
cytohesin 1
chr10_+_79970715 0.11 ENSMUST00000045085.1
glutamate receptor, ionotropic, NMDA3B
chr10_+_81137953 0.11 ENSMUST00000117956.1
zinc finger and BTB domain containing 7a
chr11_+_98446826 0.11 ENSMUST00000019456.4
growth factor receptor bound protein 7
chr12_+_83763628 0.11 ENSMUST00000121733.1
papilin, proteoglycan-like sulfated glycoprotein
chr14_-_55560340 0.10 ENSMUST00000066106.3
RIKEN cDNA A730061H03 gene
chr9_+_110117703 0.10 ENSMUST00000098355.3
predicted gene 10615
chr17_+_86963077 0.10 ENSMUST00000024956.8
ras homolog gene family, member Q
chr2_-_170497141 0.10 ENSMUST00000038824.5
cytochrome P450, family 24, subfamily a, polypeptide 1
chrY_-_1245685 0.10 ENSMUST00000143286.1
ENSMUST00000137048.1
ENSMUST00000069309.7
ENSMUST00000139365.1
ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome
chr16_+_58670208 0.10 ENSMUST00000060077.5
coproporphyrinogen oxidase
chr15_-_39857459 0.10 ENSMUST00000022915.3
ENSMUST00000110306.1
dihydropyrimidinase
chr17_+_56326045 0.10 ENSMUST00000139679.1
ENSMUST00000025036.4
ENSMUST00000086835.5
lysine (K)-specific demethylase 4B
chr14_-_70524068 0.10 ENSMUST00000022692.3
surfactant associated protein C
chr10_+_82985473 0.10 ENSMUST00000040110.7
carbohydrate sulfotransferase 11
chr8_+_104540800 0.10 ENSMUST00000056051.4
carbonic anhydrase 7
chr3_+_132684106 0.10 ENSMUST00000169172.1
ENSMUST00000029664.6
TBC1 domain containing kinase
chr11_-_85139939 0.09 ENSMUST00000108075.2
ubiquitin specific peptidase 32
chr2_-_144527341 0.09 ENSMUST00000163701.1
ENSMUST00000081982.5
double zinc ribbon and ankyrin repeat domains 1
chr14_+_25607797 0.09 ENSMUST00000160229.1
zinc finger, MIZ-type containing 1
chr17_+_37050631 0.09 ENSMUST00000172792.1
ENSMUST00000174347.1
gamma-aminobutyric acid (GABA) B receptor, 1
chr4_-_154097105 0.09 ENSMUST00000105643.1
ENSMUST00000133533.1
ENSMUST00000097762.4
transformation related protein 73
chr11_-_48826655 0.09 ENSMUST00000104959.1
predicted gene 12184
chr5_-_66151903 0.09 ENSMUST00000167950.1
RNA binding motif protein 47
chr9_+_59750876 0.09 ENSMUST00000136740.1
ENSMUST00000135298.1
ENSMUST00000128341.1
myosin IXa
chr5_+_5573952 0.09 ENSMUST00000101627.2
predicted gene 8773
chr6_+_61180313 0.09 ENSMUST00000126214.1
coiled-coil serine rich 1
chr12_+_3807076 0.09 ENSMUST00000174817.1
DNA methyltransferase 3A
chr14_-_37098211 0.09 ENSMUST00000022337.9
cadherin-related family member 1
chr12_-_111813834 0.09 ENSMUST00000021715.5
X-ray repair complementing defective repair in Chinese hamster cells 3
chr3_-_66981279 0.09 ENSMUST00000162098.2
short stature homeobox 2
chr5_-_24601961 0.09 ENSMUST00000030791.7
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr12_-_76709997 0.09 ENSMUST00000166101.1
spectrin beta, erythrocytic
chr7_+_127800844 0.09 ENSMUST00000106271.1
ENSMUST00000138432.1
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
chr6_+_86404336 0.08 ENSMUST00000113713.2
ENSMUST00000113708.1
cytotoxic granule-associated RNA binding protein 1
chr4_-_70534904 0.08 ENSMUST00000107359.2
multiple EGF-like-domains 9
chr14_-_30353468 0.08 ENSMUST00000112249.1
calcium channel, voltage-dependent, L type, alpha 1D subunit
chr7_-_139978709 0.08 ENSMUST00000121412.1
RIKEN cDNA 6430531B16 gene
chr1_+_179668202 0.08 ENSMUST00000040538.3
saccharopine dehydrogenase (putative)
chr11_-_100354040 0.08 ENSMUST00000173630.1
huntingtin-associated protein 1
chr7_+_45684398 0.08 ENSMUST00000107742.2
ENSMUST00000183120.1
netrin 5
chr7_-_30671571 0.08 ENSMUST00000051495.5
Pmis2, sperm specific protein
chr7_-_100656953 0.08 ENSMUST00000107046.1
ENSMUST00000107045.1
ENSMUST00000139708.1
pleckstrin homology domain containing, family B (evectins) member 1
chr9_+_88438598 0.08 ENSMUST00000181138.1
RIKEN cDNA 4932427H20 gene
chrX_+_86191764 0.08 ENSMUST00000026036.4
nuclear receptor subfamily 0, group B, member 1
chr2_-_168590315 0.08 ENSMUST00000109184.1
nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2
chr10_+_13966268 0.08 ENSMUST00000015645.4
human immunodeficiency virus type I enhancer binding protein 2
chr19_+_4839366 0.08 ENSMUST00000088653.2
coiled-coil domain containing 87
chr1_+_191906743 0.08 ENSMUST00000044954.6
solute carrier family 30 (zinc transporter), member 1
chr14_+_3449379 0.08 ENSMUST00000096168.5
predicted gene 10408
chr5_-_122779278 0.08 ENSMUST00000111668.3
calcium/calmodulin-dependent protein kinase kinase 2, beta
chr9_+_55149364 0.08 ENSMUST00000121677.1
ubiquitin-conjugating enzyme E2Q (putative) 2
chr14_-_73325773 0.07 ENSMUST00000022701.6
retinoblastoma 1
chr11_-_98149551 0.07 ENSMUST00000103143.3
F-box and leucine-rich repeat protein 20
chr9_+_114515697 0.07 ENSMUST00000180393.1
RIKEN cDNA C130032M10 gene
chr11_-_106788845 0.07 ENSMUST00000123339.1
DEAD (Asp-Glu-Ala-Asp) box polypeptide 5
chr7_+_30291941 0.07 ENSMUST00000144508.1
CAP-GLY domain containing linker protein 3
chr4_+_108165449 0.07 ENSMUST00000116309.3
ENSMUST00000116307.1
enoyl Coenzyme A hydratase domain containing 2
chrX_+_71364901 0.07 ENSMUST00000132837.1
myotubularin related protein 1
chr11_-_3371307 0.07 ENSMUST00000101642.3
ENSMUST00000101640.3
LIM motif-containing protein kinase 2
chr10_-_17947997 0.07 ENSMUST00000037879.6
headcase homolog (Drosophila)
chr6_+_63255971 0.07 ENSMUST00000159561.1
ENSMUST00000095852.3
glutamate receptor, ionotropic, delta 2
chr19_+_46397009 0.07 ENSMUST00000118440.1
suppressor of fused homolog (Drosophila)
chr11_+_3332426 0.07 ENSMUST00000136474.1
phosphoinositide-3-kinase interacting protein 1
chr10_+_81575257 0.07 ENSMUST00000135211.1
transducin-like enhancer of split 2, homolog of Drosophila E(spl)
chr1_-_38129618 0.07 ENSMUST00000027251.6
REV1 homolog (S. cerevisiae)
chr11_+_60777525 0.07 ENSMUST00000056907.6
ENSMUST00000102667.3
Smith-Magenis syndrome chromosome region, candidate 8 homolog (human)
chr3_-_104511812 0.07 ENSMUST00000046316.6
leucine-rich repeats and immunoglobulin-like domains 2
chr16_-_89960815 0.07 ENSMUST00000002588.3
T cell lymphoma invasion and metastasis 1

Network of associatons between targets according to the STRING database.

First level regulatory network of Zic3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0090472 dibasic protein processing(GO:0090472)
0.1 1.1 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.1 0.5 GO:0035524 proline transmembrane transport(GO:0035524)
0.1 0.8 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.1 0.4 GO:0070889 platelet alpha granule organization(GO:0070889)
0.1 0.3 GO:1904978 regulation of endosome organization(GO:1904978) positive regulation of endosome organization(GO:1904980)
0.1 0.2 GO:2000724 regulation of phenotypic switching(GO:1900239) negative regulation of vascular associated smooth muscle cell migration(GO:1904753) regulation of cardiac vascular smooth muscle cell differentiation(GO:2000722) positive regulation of cardiac vascular smooth muscle cell differentiation(GO:2000724)
0.1 0.9 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.1 0.3 GO:0061386 closure of optic fissure(GO:0061386)
0.1 0.2 GO:0010751 regulation of arginine metabolic process(GO:0000821) negative regulation of nitric oxide mediated signal transduction(GO:0010751) negative regulation of cellular amino acid metabolic process(GO:0045763) regulation of adrenergic receptor signaling pathway involved in heart process(GO:1901204)
0.1 0.4 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.1 0.3 GO:0060178 regulation of exocyst localization(GO:0060178)
0.1 0.2 GO:0060220 camera-type eye photoreceptor cell fate commitment(GO:0060220)
0.1 0.2 GO:0072108 positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis(GO:0072108)
0.0 0.3 GO:2000354 regulation of ovarian follicle development(GO:2000354)
0.0 0.2 GO:0046967 cytosol to ER transport(GO:0046967)
0.0 0.5 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.1 GO:1902869 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) regulation of amacrine cell differentiation(GO:1902869)
0.0 0.4 GO:0035754 B cell chemotaxis(GO:0035754)
0.0 0.2 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
0.0 0.2 GO:0009436 glyoxylate catabolic process(GO:0009436)
0.0 0.2 GO:1902608 regulation of large conductance calcium-activated potassium channel activity(GO:1902606) positive regulation of large conductance calcium-activated potassium channel activity(GO:1902608)
0.0 0.2 GO:1900619 acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.0 0.2 GO:0060155 platelet dense granule organization(GO:0060155)
0.0 0.1 GO:0071930 negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.0 0.4 GO:0042538 hyperosmotic salinity response(GO:0042538)
0.0 0.2 GO:0006538 glutamate catabolic process(GO:0006538)
0.0 0.1 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.0 0.2 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.1 GO:0032849 positive regulation of cellular pH reduction(GO:0032849)
0.0 0.1 GO:0048687 positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) positive regulation of retinal ganglion cell axon guidance(GO:1902336)
0.0 0.1 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0 0.1 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.0 0.2 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.0 0.5 GO:0070831 basement membrane assembly(GO:0070831)
0.0 0.1 GO:0010956 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956)
0.0 0.4 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.1 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.0 0.1 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 0.1 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.0 0.1 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.0 0.2 GO:0002838 negative regulation of response to tumor cell(GO:0002835) negative regulation of immune response to tumor cell(GO:0002838)
0.0 0.2 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.2 GO:0030046 parallel actin filament bundle assembly(GO:0030046)
0.0 0.1 GO:0071579 regulation of zinc ion transport(GO:0071579)
0.0 0.1 GO:1900149 positive regulation of Schwann cell migration(GO:1900149)
0.0 0.1 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.0 0.1 GO:0032901 positive regulation of neurotrophin production(GO:0032901)
0.0 0.7 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.1 GO:0061762 CAMKK-AMPK signaling cascade(GO:0061762)
0.0 0.2 GO:0008228 opsonization(GO:0008228)
0.0 0.1 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.0 0.5 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.1 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.0 0.0 GO:0060722 spongiotrophoblast cell proliferation(GO:0060720) cell proliferation involved in embryonic placenta development(GO:0060722)
0.0 0.1 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.1 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.1 GO:0014053 negative regulation of gamma-aminobutyric acid secretion(GO:0014053)
0.0 0.1 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.0 0.1 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.0 0.2 GO:1901620 regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901620)
0.0 0.1 GO:0071816 maintenance of unfolded protein(GO:0036506) tail-anchored membrane protein insertion into ER membrane(GO:0071816) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.0 0.1 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.0 0.2 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.2 GO:0060644 mammary gland epithelial cell differentiation(GO:0060644)
0.0 0.3 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0 0.0 GO:0036343 psychomotor behavior(GO:0036343)
0.0 0.1 GO:0036515 serotonergic neuron axon guidance(GO:0036515)
0.0 0.0 GO:0060912 cardiac cell fate specification(GO:0060912)
0.0 0.8 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.0 0.1 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.0 0.0 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.0 0.0 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.1 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.0 0.0 GO:0035621 ER to Golgi ceramide transport(GO:0035621) ceramide transport(GO:0035627)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0005607 laminin-2 complex(GO:0005607)
0.0 0.1 GO:0043512 inhibin-betaglycan-ActRII complex(GO:0034673) inhibin A complex(GO:0043512)
0.0 0.1 GO:0097454 Schwann cell microvillus(GO:0097454)
0.0 0.2 GO:0044305 calyx of Held(GO:0044305)
0.0 0.1 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.0 0.5 GO:0001533 cornified envelope(GO:0001533)
0.0 0.8 GO:0001741 XY body(GO:0001741)
0.0 0.2 GO:0042825 TAP complex(GO:0042825)
0.0 0.5 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.0 0.7 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.1 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.4 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.1 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.0 0.1 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.4 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.1 GO:0097165 nuclear stress granule(GO:0097165)
0.0 0.2 GO:0045180 basal cortex(GO:0045180)
0.0 0.1 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.1 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 0.1 GO:0031501 mannosyltransferase complex(GO:0031501)
0.0 0.3 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.0 0.2 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.1 GO:0008091 spectrin(GO:0008091)
0.0 0.1 GO:0036156 inner dynein arm(GO:0036156)
0.0 0.5 GO:0032590 dendrite membrane(GO:0032590)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 0.8 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 0.4 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.1 0.4 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 0.3 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.1 0.2 GO:0030226 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.1 0.7 GO:0005522 profilin binding(GO:0005522)
0.1 0.2 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.0 0.5 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.0 0.2 GO:0004104 cholinesterase activity(GO:0004104)
0.0 0.2 GO:0046980 peptide antigen-transporting ATPase activity(GO:0015433) tapasin binding(GO:0046980)
0.0 0.4 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.2 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.0 0.2 GO:0004966 galanin receptor activity(GO:0004966)
0.0 0.2 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.5 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.2 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.1 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.0 0.1 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.2 GO:0005113 patched binding(GO:0005113)
0.0 0.1 GO:0035500 MH2 domain binding(GO:0035500)
0.0 0.3 GO:0015377 cation:chloride symporter activity(GO:0015377)
0.0 0.1 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.0 0.3 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.1 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.0 0.2 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.5 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 0.1 GO:0097001 ceramide binding(GO:0097001)
0.0 0.2 GO:0034711 inhibin binding(GO:0034711)
0.0 0.7 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.2 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.4 GO:0005549 odorant binding(GO:0005549)
0.0 0.3 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.1 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 0.1 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.0 0.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.5 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.1 GO:0002054 nucleobase binding(GO:0002054) hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.2 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.1 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.0 0.1 GO:0000150 recombinase activity(GO:0000150)
0.0 0.3 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.2 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.1 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.0 0.4 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.1 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.0 0.2 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.1 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.0 GO:0031711 bradykinin receptor binding(GO:0031711)
0.0 0.1 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.3 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.7 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.5 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 1.1 PID E2F PATHWAY E2F transcription factor network
0.0 0.8 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.0 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.5 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.4 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.2 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.2 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.6 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.5 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits