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12D miR HR13_24

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Results for Gsx1_Alx1_Mixl1_Lbx2

Z-value: 0.86

Motif logo

Transcription factors associated with Gsx1_Alx1_Mixl1_Lbx2

Gene Symbol Gene ID Gene Info
ENSMUSG00000053129.5 GS homeobox 1
ENSMUSG00000036602.7 ALX homeobox 1
ENSMUSG00000026497.7 Mix1 homeobox-like 1 (Xenopus laevis)
ENSMUSG00000034968.2 ladybird homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Alx1mm10_v2_chr10_-_103029043_103029054-0.624.1e-02Click!
Lbx2mm10_v2_chr6_+_83086365_83086365-0.614.7e-02Click!

Activity profile of Gsx1_Alx1_Mixl1_Lbx2 motif

Sorted Z-values of Gsx1_Alx1_Mixl1_Lbx2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr15_-_34356421 2.48 ENSMUST00000179647.1
RIKEN cDNA 9430069I07 gene
chr1_+_110099295 2.19 ENSMUST00000134301.1
cadherin 7, type 2
chr2_-_37359274 1.99 ENSMUST00000009174.8
phosducin-like
chr6_+_29853746 1.65 ENSMUST00000064872.6
ENSMUST00000152581.1
ENSMUST00000176265.1
ENSMUST00000154079.1
S-adenosylhomocysteine hydrolase-like 2
chr15_-_67113909 1.59 ENSMUST00000092640.5
ST3 beta-galactoside alpha-2,3-sialyltransferase 1
chr3_-_75270073 1.57 ENSMUST00000039047.4
serine (or cysteine) peptidase inhibitor, clade I, member 2
chr3_+_60081861 1.45 ENSMUST00000029326.5
succinate receptor 1
chr5_-_62765618 1.41 ENSMUST00000159470.1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr6_-_147264124 1.36 ENSMUST00000052296.6
parathyroid hormone-like peptide
chr6_-_115592571 1.29 ENSMUST00000112957.1
RIKEN cDNA 2510049J12 gene
chr1_-_79440039 1.14 ENSMUST00000049972.4
secretogranin II
chr3_+_159839729 1.13 ENSMUST00000068952.5
wntless homolog (Drosophila)
chr1_+_109983737 1.07 ENSMUST00000172005.1
cadherin 7, type 2
chr13_+_23574381 1.02 ENSMUST00000090776.4
histone cluster 1, H2ad
chr10_-_24092320 1.02 ENSMUST00000092654.2
trace amine-associated receptor 8B
chr14_-_110755100 0.97 ENSMUST00000078386.2
SLIT and NTRK-like family, member 6
chr5_+_95956916 0.96 ENSMUST00000023840.5
chemokine (C-X-C motif) ligand 13
chr17_+_34305883 0.96 ENSMUST00000074557.8
histocompatibility 2, class II antigen E beta
chr15_+_25773985 0.96 ENSMUST00000125667.1
myosin X
chrX_+_159697308 0.95 ENSMUST00000123433.1
SH3-domain kinase binding protein 1
chr9_-_40962333 0.95 ENSMUST00000160120.1
RIKEN cDNA 4931429I11 gene
chr16_-_42340595 0.93 ENSMUST00000102817.4
growth associated protein 43
chr7_+_126950518 0.90 ENSMUST00000106335.1
ENSMUST00000146017.1
seizure related 6 homolog like 2
chrX_+_164438039 0.88 ENSMUST00000033755.5
ankyrin repeat and SOCS box-containing 11
chr7_+_126950687 0.88 ENSMUST00000106333.1
seizure related 6 homolog like 2
chr13_+_23575753 0.87 ENSMUST00000105105.1
histone cluster 1, H3d
chr13_-_23574196 0.85 ENSMUST00000105106.1
histone cluster 1, H2bf
chr17_+_17402672 0.83 ENSMUST00000115576.2
limb expression 1 homolog (chicken)
chrX_+_164436987 0.81 ENSMUST00000036858.4
ankyrin repeat and SOCS box-containing 11
chr1_-_72284248 0.78 ENSMUST00000097698.4
ENSMUST00000027381.6
peroxisomal trans-2-enoyl-CoA reductase
chr2_+_125136692 0.73 ENSMUST00000099452.2
cortexin 2
chrX_-_143933204 0.73 ENSMUST00000112851.1
ENSMUST00000112856.2
ENSMUST00000033642.3
doublecortin
chr6_+_123262107 0.71 ENSMUST00000032240.2
C-type lectin domain family 4, member d
chr13_-_102906046 0.70 ENSMUST00000171791.1
microtubule associated serine/threonine kinase family member 4
chr6_-_116716888 0.69 ENSMUST00000056623.6
transmembrane protein 72
chr5_+_139543889 0.69 ENSMUST00000174792.1
ENSMUST00000031523.8
UNC homeobox
chr4_-_129558355 0.68 ENSMUST00000167288.1
ENSMUST00000134336.1
lymphocyte protein tyrosine kinase
chr13_-_102905740 0.67 ENSMUST00000167462.1
microtubule associated serine/threonine kinase family member 4
chr7_+_30458280 0.66 ENSMUST00000126297.1
nephrosis 1, nephrin
chr10_-_24101951 0.66 ENSMUST00000170267.1
trace amine-associated receptor 8C
chr10_+_39612934 0.65 ENSMUST00000019987.6
TRAF3 interacting protein 2
chrX_-_143933089 0.65 ENSMUST00000087313.3
doublecortin
chr11_+_16752203 0.63 ENSMUST00000102884.3
ENSMUST00000020329.6
epidermal growth factor receptor
chr2_+_105126505 0.63 ENSMUST00000143043.1
Wilms tumor 1 homolog
chr5_+_20702129 0.60 ENSMUST00000101556.4
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr2_+_86046451 0.60 ENSMUST00000079298.2
olfactory receptor 1034
chr3_+_134236483 0.59 ENSMUST00000181904.1
ENSMUST00000053048.9
CXXC finger 4
chr8_+_107031218 0.59 ENSMUST00000034388.9
vacuolar protein sorting 4a (yeast)
chr4_-_42661893 0.58 ENSMUST00000108006.3
interleukin 11 receptor, alpha chain 2
chr1_+_72284367 0.58 ENSMUST00000027380.5
ENSMUST00000141783.1
transmembrane protein 169
chr3_-_133234886 0.57 ENSMUST00000147041.3
ENSMUST00000161022.2
Rho guanine nucleotide exchange factor (GEF) 38
chr11_-_99322943 0.56 ENSMUST00000038004.2
keratin 25
chr9_+_43310763 0.56 ENSMUST00000034511.5
tripartite motif-containing 29
chr2_+_57997884 0.55 ENSMUST00000112616.1
ENSMUST00000166729.1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5
chr7_+_51879041 0.55 ENSMUST00000107591.2
growth arrest specific 2
chr12_+_111814170 0.54 ENSMUST00000021714.7
zinc finger, FYVE domain containing 21
chr3_+_146121655 0.54 ENSMUST00000039450.4
mucolipin 3
chr17_+_35533194 0.54 ENSMUST00000025273.8
psoriasis susceptibility 1 candidate 2 (human)
chr7_+_51880312 0.54 ENSMUST00000145049.1
growth arrest specific 2
chr3_+_106113229 0.51 ENSMUST00000079132.5
ENSMUST00000139086.1
chitinase, acidic
chr4_-_45532470 0.51 ENSMUST00000147448.1
src homology 2 domain-containing transforming protein B
chr12_+_99964499 0.50 ENSMUST00000177549.1
ENSMUST00000160413.1
ENSMUST00000162221.1
ENSMUST00000049788.8
potassium channel, subfamily K, member 13
chr7_-_100656953 0.49 ENSMUST00000107046.1
ENSMUST00000107045.1
ENSMUST00000139708.1
pleckstrin homology domain containing, family B (evectins) member 1
chr5_-_137684665 0.49 ENSMUST00000100544.4
ENSMUST00000031736.9
ENSMUST00000151839.1
ArfGAP with FG repeats 2
chr18_+_57468478 0.49 ENSMUST00000091892.2
cortexin 3
chr12_-_4841583 0.48 ENSMUST00000020964.5
FK506 binding protein 1b
chr15_-_11037968 0.48 ENSMUST00000058007.5
relaxin family peptide receptor 3
chr17_+_25188380 0.48 ENSMUST00000039734.5
unkempt-like (Drosophila)
chr11_+_103133333 0.47 ENSMUST00000124928.1
ENSMUST00000062530.4
hexamethylene bis-acetamide inducible 2
chr11_-_99244058 0.46 ENSMUST00000103132.3
ENSMUST00000038214.6
keratin 222
chr17_+_45734506 0.46 ENSMUST00000180558.1
RIKEN cDNA F630040K05 gene
chr4_+_99030946 0.45 ENSMUST00000030280.6
angiopoietin-like 3
chr6_-_128275577 0.45 ENSMUST00000130454.1
TEA domain family member 4
chr13_-_113663670 0.45 ENSMUST00000054650.4
heat shock protein 3
chr5_-_131616599 0.45 ENSMUST00000161804.1
autism susceptibility candidate 2
chrX_-_9256899 0.44 ENSMUST00000115553.2
predicted gene 14862
chr15_+_9436028 0.44 ENSMUST00000042360.3
calcyphosine-like
chr9_+_21955747 0.44 ENSMUST00000053583.5
SWIM type zinc finger 7 associated protein 1
chr14_-_49245389 0.43 ENSMUST00000130853.1
ENSMUST00000022398.7
RIKEN cDNA 1700011H14 gene
chr6_-_138079916 0.43 ENSMUST00000171804.1
solute carrier family 15, member 5
chrX_+_103356464 0.43 ENSMUST00000116547.2
cysteine-rich hydrophobic domain 1
chr11_-_109298066 0.42 ENSMUST00000106706.1
regulator of G-protein signaling 9
chr11_+_60537978 0.41 ENSMUST00000044250.3
alkB, alkylation repair homolog 5 (E. coli)
chr3_-_122619442 0.41 ENSMUST00000162947.1
formin binding protein 1-like
chr3_+_108186332 0.41 ENSMUST00000050909.6
ENSMUST00000106659.2
ENSMUST00000106656.1
ENSMUST00000106661.2
adhesion molecule with Ig like domain 1
chr7_+_64185459 0.41 ENSMUST00000177102.2
ENSMUST00000107519.1
ENSMUST00000137650.1
ENSMUST00000032737.5
ENSMUST00000107515.1
ENSMUST00000144996.1
transient receptor potential cation channel, subfamily M, member 1
chr14_+_79515618 0.40 ENSMUST00000110835.1
E74-like factor 1
chr11_+_103133303 0.40 ENSMUST00000107037.1
hexamethylene bis-acetamide inducible 2
chrX_-_164258186 0.40 ENSMUST00000112265.2
BMX non-receptor tyrosine kinase
chr11_-_109298121 0.39 ENSMUST00000020920.3
regulator of G-protein signaling 9
chr5_+_14025305 0.39 ENSMUST00000073957.6
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr13_+_23555023 0.39 ENSMUST00000045301.6
histone cluster 1, H1d
chr6_+_30610984 0.39 ENSMUST00000062758.4
carboxypeptidase A5
chr8_+_23411490 0.39 ENSMUST00000033952.7
secreted frizzled-related protein 1
chr13_-_71963713 0.39 ENSMUST00000077337.8
Iroquois related homeobox 1 (Drosophila)
chr6_+_37870786 0.38 ENSMUST00000120428.1
ENSMUST00000031859.7
tripartite motif-containing 24
chr4_+_102254993 0.38 ENSMUST00000106908.2
phosphodiesterase 4B, cAMP specific
chr9_-_22208546 0.38 ENSMUST00000167359.1
RIKEN cDNA 1810064F22 gene
chr17_-_31636631 0.38 ENSMUST00000135425.1
ENSMUST00000151718.1
ENSMUST00000155814.1
cystathionine beta-synthase
chr1_-_9298499 0.38 ENSMUST00000132064.1
syntrophin, gamma 1
chr14_+_33941021 0.38 ENSMUST00000100720.1
growth differentiation factor 2
chr11_+_67798269 0.37 ENSMUST00000168612.1
ENSMUST00000040574.4
dehydrogenase/reductase (SDR family) member 7C
chr18_+_84851338 0.37 ENSMUST00000160180.1
cytochrome b-5
chr7_+_29170345 0.36 ENSMUST00000033886.7
gametogenetin
chr4_-_129558387 0.36 ENSMUST00000067240.4
lymphocyte protein tyrosine kinase
chr17_-_57247632 0.36 ENSMUST00000005975.6
G protein-coupled receptor 108
chr8_-_3624989 0.36 ENSMUST00000142431.1
Purkinje cell protein 2 (L7)
chr9_+_57825918 0.36 ENSMUST00000165858.1
predicted gene 17231
chr11_-_109298090 0.36 ENSMUST00000106704.2
regulator of G-protein signaling 9
chr18_+_68337504 0.36 ENSMUST00000172148.1
melanocortin 5 receptor
chr18_-_38866702 0.36 ENSMUST00000115582.1
fibroblast growth factor 1
chr6_+_30611029 0.35 ENSMUST00000115138.1
carboxypeptidase A5
chr5_+_92137896 0.34 ENSMUST00000031355.6
USO1 vesicle docking factor
chr9_+_5298517 0.34 ENSMUST00000027015.5
caspase 1
chrX_-_139871637 0.34 ENSMUST00000033811.7
ENSMUST00000087401.5
microrchidia 4
chr4_-_155056784 0.34 ENSMUST00000131173.2
phospholipase C, eta 2
chr2_-_5063996 0.34 ENSMUST00000114996.1
optineurin
chr7_-_73537621 0.33 ENSMUST00000172704.1
chromodomain helicase DNA binding protein 2
chr3_+_125404292 0.33 ENSMUST00000144344.1
N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
chr9_-_71163224 0.33 ENSMUST00000074465.2
aquaporin 9
chr2_+_86007778 0.33 ENSMUST00000062166.1
olfactory receptor 1032
chr11_+_26387194 0.33 ENSMUST00000109509.1
ENSMUST00000136830.1
Fanconi anemia, complementation group L
chr15_+_31224371 0.33 ENSMUST00000044524.9
death-associated protein
chr17_+_7170101 0.33 ENSMUST00000024575.6
ribosomal protein S6 kinase, polypeptide 2
chrX_+_56454871 0.32 ENSMUST00000039374.2
ENSMUST00000101553.2
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B
chr3_-_53017195 0.32 ENSMUST00000036665.4
component of oligomeric golgi complex 6
chr3_-_133234939 0.32 ENSMUST00000161932.1
Rho guanine nucleotide exchange factor (GEF) 38
chr15_-_101892916 0.31 ENSMUST00000100179.1
keratin 76
chr5_+_8893677 0.31 ENSMUST00000003717.8
ATP-binding cassette, sub-family B (MDR/TAP), member 4
chr8_-_3625025 0.31 ENSMUST00000133459.1
Purkinje cell protein 2 (L7)
chr5_-_70842617 0.31 ENSMUST00000031119.1
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1
chr3_+_121291725 0.31 ENSMUST00000039442.7
asparagine-linked glycosylation 14
chr1_-_176213934 0.31 ENSMUST00000111167.1
phospholipase D family, member 5
chr3_-_141982224 0.31 ENSMUST00000029948.8
bone morphogenetic protein receptor, type 1B
chrX_+_160768013 0.31 ENSMUST00000033650.7
retinoschisis (X-linked, juvenile) 1 (human)
chr7_+_140247316 0.30 ENSMUST00000164583.1
ENSMUST00000093984.2
RIKEN cDNA 5830411N06 gene
chr15_-_58364148 0.30 ENSMUST00000068515.7
annexin A13
chr8_-_69089200 0.30 ENSMUST00000037478.6
solute carrier family 18 (vesicular monoamine), member 1
chr6_+_92816460 0.30 ENSMUST00000057977.3
RIKEN cDNA A730049H05 gene
chr11_-_103697898 0.29 ENSMUST00000021329.7
golgi SNAP receptor complex member 2
chr6_-_124779686 0.29 ENSMUST00000147669.1
ENSMUST00000128697.1
ENSMUST00000032218.3
ENSMUST00000112475.2
leucine rich repeat containing 23
chr11_+_59306920 0.28 ENSMUST00000000128.3
ENSMUST00000108783.3
wingless-type MMTV integration site 9A
chr1_+_195017399 0.28 ENSMUST00000181273.1
RIKEN cDNA A330023F24 gene
chr5_-_66054499 0.28 ENSMUST00000145625.1
RNA binding motif protein 47
chr11_+_101582236 0.28 ENSMUST00000039581.7
ENSMUST00000100403.2
ENSMUST00000107194.1
ENSMUST00000128614.1
transmembrane protein 106A
chr6_+_29859686 0.27 ENSMUST00000134438.1
S-adenosylhomocysteine hydrolase-like 2
chr19_-_56822161 0.27 ENSMUST00000118592.1
RIKEN cDNA A630007B06 gene
chr14_-_70429072 0.27 ENSMUST00000048129.4
piwi-like RNA-mediated gene silencing 2
chr4_-_14621805 0.27 ENSMUST00000042221.7
solute carrier family 26, member 7
chr6_-_126645784 0.26 ENSMUST00000055168.3
potassium voltage-gated channel, shaker-related subfamily, member 1
chr11_-_103697661 0.26 ENSMUST00000107013.2
golgi SNAP receptor complex member 2
chr13_+_67833235 0.26 ENSMUST00000060609.7
predicted gene 10037
chr6_+_29859662 0.26 ENSMUST00000128927.2
S-adenosylhomocysteine hydrolase-like 2
chr17_-_83846769 0.26 ENSMUST00000000687.7
3-hydroxyanthranilate 3,4-dioxygenase
chr4_+_150853919 0.25 ENSMUST00000073600.2
ERBB receptor feedback inhibitor 1
chr11_-_50292302 0.25 ENSMUST00000059458.4
mastermind like 1 (Drosophila)
chr7_+_45621805 0.25 ENSMUST00000033100.4
izumo sperm-egg fusion 1
chr7_+_29170204 0.25 ENSMUST00000098609.2
gametogenetin
chr8_-_61902669 0.25 ENSMUST00000121785.1
ENSMUST00000034057.7
palladin, cytoskeletal associated protein
chr4_-_3872105 0.25 ENSMUST00000105158.1
Moloney sarcoma oncogene
chr2_-_37359196 0.24 ENSMUST00000147703.1
phosducin-like
chr12_-_91849081 0.24 ENSMUST00000167466.1
ENSMUST00000021347.5
ENSMUST00000178462.1
sel-1 suppressor of lin-12-like (C. elegans)
chr3_+_96268654 0.24 ENSMUST00000098843.2
histone cluster 2, H3b
chr18_+_23752333 0.24 ENSMUST00000170802.1
ENSMUST00000155708.1
ENSMUST00000118826.2
microtubule-associated protein, RP/EB family, member 2
chr6_-_72362382 0.24 ENSMUST00000114095.1
ENSMUST00000069595.6
ENSMUST00000069580.5
ring finger protein 181
chr6_-_137571007 0.24 ENSMUST00000100841.2
epidermal growth factor receptor pathway substrate 8
chr12_+_109545390 0.23 ENSMUST00000146701.1
maternally expressed 3
chrX_-_60893430 0.23 ENSMUST00000135107.2
SRY-box containing gene 3
chr10_-_128525859 0.23 ENSMUST00000026427.6
extended synaptotagmin-like protein 1
chr2_-_37359235 0.23 ENSMUST00000112940.1
phosducin-like
chrX_+_107792583 0.23 ENSMUST00000101292.2
family with sequence similarity 46, member D
chr1_-_74885322 0.23 ENSMUST00000159232.1
ENSMUST00000068631.3
FEV (ETS oncogene family)
chr7_+_5015466 0.23 ENSMUST00000086349.3
zinc finger protein 524
chr2_+_23069210 0.23 ENSMUST00000155602.1
acyl-Coenzyme A binding domain containing 5
chr7_-_5014645 0.23 ENSMUST00000165320.1
Flt3 interacting zinc finger protein 1
chr4_-_43046196 0.23 ENSMUST00000036462.5
family with sequence similarity 214, member B
chr6_+_29859374 0.22 ENSMUST00000115238.3
S-adenosylhomocysteine hydrolase-like 2
chr5_+_135168382 0.22 ENSMUST00000111187.3
ENSMUST00000111188.1
B cell CLL/lymphoma 7B
chr14_+_55559993 0.22 ENSMUST00000117236.1
DDB1 and CUL4 associated factor 11
chr1_-_9299238 0.22 ENSMUST00000140295.1
syntrophin, gamma 1
chr8_+_23669653 0.22 ENSMUST00000042352.4
zinc finger, matrin type 4
chr2_+_109917639 0.22 ENSMUST00000046548.7
ENSMUST00000111037.2
leucine-rich repeat-containing G protein-coupled receptor 4
chr12_+_55089202 0.22 ENSMUST00000021407.10
signal recognition particle 54A
chr5_-_87569023 0.22 ENSMUST00000113314.2
sulfotransferase family 1D, member 1
chr17_+_46161021 0.22 ENSMUST00000024748.7
ENSMUST00000172170.1
GTP binding protein 2
chr13_+_22043189 0.22 ENSMUST00000110452.1
histone cluster 1, H2bj
chrX_-_133981765 0.21 ENSMUST00000113297.2
ENSMUST00000174542.1
ENSMUST00000033608.8
ENSMUST00000113294.1
synaptotagmin-like 4
chr18_+_37518341 0.21 ENSMUST00000097609.1
protocadherin beta 22
chr16_-_74411292 0.21 ENSMUST00000117200.1
roundabout homolog 2 (Drosophila)
chr18_+_61555689 0.21 ENSMUST00000167187.1
casein kinase 1, alpha 1
chr5_+_36484578 0.21 ENSMUST00000060100.1
coiled-coil domain containing 96
chr4_+_80834298 0.21 ENSMUST00000102831.1
tyrosinase-related protein 1
chr4_+_80834123 0.21 ENSMUST00000133655.1
ENSMUST00000006151.6
tyrosinase-related protein 1
chr13_+_23738804 0.21 ENSMUST00000040914.1
histone cluster 1, H1c
chr11_-_26591729 0.20 ENSMUST00000109504.1
vaccinia related kinase 2
chr5_+_17574726 0.20 ENSMUST00000169603.1
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr6_+_142298419 0.20 ENSMUST00000041993.2
islet amyloid polypeptide
chr8_+_45658731 0.20 ENSMUST00000143820.1
ENSMUST00000132139.1
sorbin and SH3 domain containing 2
chr7_+_140247267 0.20 ENSMUST00000059882.6
RIKEN cDNA 5830411N06 gene
chr12_+_52699297 0.20 ENSMUST00000095737.3
A kinase (PRKA) anchor protein 6

Network of associatons between targets according to the STRING database.

First level regulatory network of Gsx1_Alx1_Mixl1_Lbx2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.5 GO:1902605 heterotrimeric G-protein complex assembly(GO:1902605)
0.4 1.1 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.3 2.4 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.2 1.0 GO:0060005 vestibular reflex(GO:0060005)
0.2 1.0 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634) negative regulation of endothelial cell chemotaxis(GO:2001027)
0.2 1.3 GO:0060648 mammary gland bud morphogenesis(GO:0060648)
0.2 0.6 GO:2001074 negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302) regulation of metanephric ureteric bud development(GO:2001074) positive regulation of metanephric ureteric bud development(GO:2001076)
0.2 0.6 GO:1903774 mitotic cytokinesis checkpoint(GO:0044878) positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.2 1.1 GO:0016198 axon choice point recognition(GO:0016198)
0.1 0.4 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.1 0.4 GO:0019343 cysteine biosynthetic process via cystathionine(GO:0019343)
0.1 0.7 GO:0038094 Fc-gamma receptor signaling pathway(GO:0038094)
0.1 0.4 GO:0006583 melanin biosynthetic process from tyrosine(GO:0006583)
0.1 0.4 GO:2000040 regulation of midbrain dopaminergic neuron differentiation(GO:1904956) regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
0.1 0.6 GO:0070459 prolactin secretion(GO:0070459)
0.1 0.3 GO:0003162 atrioventricular node development(GO:0003162)
0.1 1.3 GO:0016056 rhodopsin mediated signaling pathway(GO:0016056)
0.1 0.3 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.1 0.5 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.1 1.0 GO:0070474 positive regulation of uterine smooth muscle contraction(GO:0070474)
0.1 1.1 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.1 0.4 GO:0035553 oxidative single-stranded RNA demethylation(GO:0035553)
0.1 0.4 GO:0015855 nucleobase transport(GO:0015851) pyrimidine nucleobase transport(GO:0015855)
0.1 0.3 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
0.1 0.3 GO:0048880 hindbrain tangential cell migration(GO:0021934) sensory system development(GO:0048880)
0.1 0.7 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.1 0.4 GO:0072272 proximal/distal pattern formation involved in metanephric nephron development(GO:0072272)
0.1 0.8 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.1 0.4 GO:0015825 L-serine transport(GO:0015825)
0.1 0.5 GO:0051005 negative regulation of phospholipase activity(GO:0010519) negative regulation of lipoprotein lipase activity(GO:0051005)
0.1 0.5 GO:0001830 trophectodermal cell fate commitment(GO:0001830)
0.1 0.6 GO:0016584 nucleosome positioning(GO:0016584)
0.1 0.2 GO:0044771 meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.1 1.4 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.1 0.4 GO:0003350 pulmonary myocardium development(GO:0003350)
0.1 0.4 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.1 1.0 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.1 0.5 GO:0051775 response to redox state(GO:0051775)
0.1 0.9 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.1 1.9 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.1 0.3 GO:0000966 RNA 5'-end processing(GO:0000966)
0.1 0.5 GO:0051611 regulation of serotonin uptake(GO:0051611)
0.1 0.3 GO:0050975 sensory perception of touch(GO:0050975)
0.1 0.1 GO:1903537 meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
0.1 0.3 GO:0048165 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.1 0.2 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.1 0.5 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.1 0.2 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.1 0.8 GO:0030497 fatty acid elongation(GO:0030497)
0.1 0.2 GO:0045660 positive regulation of neutrophil differentiation(GO:0045660)
0.1 0.2 GO:2000481 positive regulation of cAMP-dependent protein kinase activity(GO:2000481)
0.1 0.9 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 0.2 GO:0030916 otic vesicle formation(GO:0030916)
0.0 0.2 GO:0060128 regulation of retinal cell programmed cell death(GO:0046668) corticotropin hormone secreting cell differentiation(GO:0060128)
0.0 0.3 GO:0019532 oxalate transport(GO:0019532)
0.0 0.3 GO:0061091 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.0 0.2 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.0 0.2 GO:0000103 sulfate assimilation(GO:0000103)
0.0 0.3 GO:0042536 negative regulation of tumor necrosis factor biosynthetic process(GO:0042536) negative regulation of cardiac muscle hypertrophy in response to stress(GO:1903243)
0.0 0.2 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 0.1 GO:1904742 regulation of telomeric DNA binding(GO:1904742)
0.0 0.3 GO:0002035 brain renin-angiotensin system(GO:0002035)
0.0 0.2 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.0 0.1 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
0.0 0.4 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.1 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.0 1.6 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.2 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.1 GO:0042488 positive regulation of odontogenesis of dentin-containing tooth(GO:0042488)
0.0 0.4 GO:0001865 NK T cell differentiation(GO:0001865)
0.0 0.9 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.2 GO:0030242 pexophagy(GO:0030242)
0.0 0.1 GO:0006868 glutamine transport(GO:0006868)
0.0 0.1 GO:0052203 modulation by symbiont of host molecular function(GO:0052055) modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
0.0 0.7 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.0 0.2 GO:0070777 gamma-aminobutyric acid biosynthetic process(GO:0009449) D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.2 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0 0.2 GO:0046874 quinolinate metabolic process(GO:0046874)
0.0 0.2 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0 2.6 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.2 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.8 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.3 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.3 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.1 GO:0015692 vanadium ion transport(GO:0015676) lead ion transport(GO:0015692)
0.0 0.1 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.0 0.6 GO:0045109 intermediate filament organization(GO:0045109)
0.0 0.2 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.3 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.0 0.2 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.0 0.4 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.2 GO:0090656 t-circle formation(GO:0090656)
0.0 0.1 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.1 GO:0051177 meiotic sister chromatid cohesion(GO:0051177)
0.0 0.5 GO:0042492 gamma-delta T cell differentiation(GO:0042492)
0.0 0.1 GO:0090166 Golgi disassembly(GO:0090166)
0.0 0.5 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 0.1 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.0 0.2 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.0 0.3 GO:0048733 sebaceous gland development(GO:0048733)
0.0 0.1 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.7 GO:0044062 regulation of excretion(GO:0044062)
0.0 0.1 GO:0030210 heparin biosynthetic process(GO:0030210)
0.0 0.1 GO:1900369 negative regulation of RNA interference(GO:1900369)
0.0 0.1 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.0 0.4 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.0 0.1 GO:0030026 cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) manganese ion homeostasis(GO:0055071)
0.0 0.5 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0 0.6 GO:1904030 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.0 3.6 GO:0008360 regulation of cell shape(GO:0008360)
0.0 0.1 GO:2000510 positive regulation of dendritic cell chemotaxis(GO:2000510)
0.0 0.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.1 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.0 0.2 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.0 GO:0060686 negative regulation of prostatic bud formation(GO:0060686)
0.0 0.1 GO:0071285 cellular response to lithium ion(GO:0071285)
0.0 0.1 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0 0.3 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.0 0.2 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.2 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.1 GO:0019344 cysteine biosynthetic process(GO:0019344)
0.0 0.1 GO:2000467 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.0 0.2 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.0 0.1 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.0 0.0 GO:1904959 regulation of electron carrier activity(GO:1904732) regulation of cytochrome-c oxidase activity(GO:1904959)
0.0 0.3 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.1 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.1 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.1 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
0.0 0.1 GO:0061727 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0 0.1 GO:0046504 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.1 GO:0006363 transcription initiation from RNA polymerase I promoter(GO:0006361) termination of RNA polymerase I transcription(GO:0006363)
0.0 0.0 GO:1901529 positive regulation of anion channel activity(GO:1901529)
0.0 0.0 GO:0050787 detoxification of mercury ion(GO:0050787)
0.0 0.2 GO:0021854 hypothalamus development(GO:0021854)
0.0 0.2 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.0 0.2 GO:0040033 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.1 GO:0045925 positive regulation of female receptivity(GO:0045925)
0.0 0.0 GO:0036233 glycine import(GO:0036233)
0.0 0.0 GO:0051684 maintenance of Golgi location(GO:0051684)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.1 0.4 GO:0035841 new growing cell tip(GO:0035841)
0.1 1.5 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 0.3 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.1 1.0 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 0.4 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.1 0.7 GO:0000815 ESCRT III complex(GO:0000815)
0.1 1.1 GO:0031045 dense core granule(GO:0031045)
0.1 0.4 GO:0005726 perichromatin fibrils(GO:0005726)
0.1 0.3 GO:1990923 PET complex(GO:1990923)
0.1 0.3 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1 0.2 GO:1990696 USH2 complex(GO:1990696)
0.0 0.2 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 1.1 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.9 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.9 GO:0031527 filopodium membrane(GO:0031527)
0.0 1.3 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.9 GO:0000242 pericentriolar material(GO:0000242)
0.0 1.1 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.3 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.4 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.2 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0 0.3 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.1 GO:0070826 paraferritin complex(GO:0070826)
0.0 2.2 GO:0005882 intermediate filament(GO:0005882)
0.0 1.1 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.3 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.8 GO:0000786 nucleosome(GO:0000786)
0.0 0.2 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 0.4 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.1 GO:0005927 muscle tendon junction(GO:0005927)
0.0 0.1 GO:0097413 Lewy body(GO:0097413)
0.0 0.2 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 0.1 GO:0032783 ELL-EAF complex(GO:0032783)
0.0 0.1 GO:0045251 mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
0.0 0.2 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.1 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.0 0.2 GO:0042581 specific granule(GO:0042581)
0.0 0.2 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 1.3 GO:0030175 filopodium(GO:0030175)
0.0 0.1 GO:0097441 basilar dendrite(GO:0097441)
0.0 0.1 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.2 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.1 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.1 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.0 0.4 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.2 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.6 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.4 2.5 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.3 2.4 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.3 0.8 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.2 1.0 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.2 0.6 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.2 1.8 GO:0001594 trace-amine receptor activity(GO:0001594)
0.2 1.0 GO:0042610 CD8 receptor binding(GO:0042610)
0.1 0.4 GO:0098809 nitrite reductase activity(GO:0098809)
0.1 0.8 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 0.9 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.1 0.9 GO:0097322 7SK snRNA binding(GO:0097322)
0.1 0.3 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.1 0.4 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.1 0.5 GO:0004966 galanin receptor activity(GO:0004966)
0.1 0.6 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.1 0.4 GO:0005350 purine nucleobase transmembrane transporter activity(GO:0005345) pyrimidine nucleobase transmembrane transporter activity(GO:0005350) nucleobase transmembrane transporter activity(GO:0015205) glycerol channel activity(GO:0015254)
0.1 0.1 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.1 1.4 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.1 0.5 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.1 0.5 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 0.3 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.1 0.4 GO:0004977 melanocortin receptor activity(GO:0004977)
0.1 0.3 GO:0034584 piRNA binding(GO:0034584)
0.1 0.3 GO:0090554 phosphatidylcholine-translocating ATPase activity(GO:0090554)
0.1 0.4 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.1 0.1 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.1 0.4 GO:0034056 estrogen response element binding(GO:0034056)
0.1 1.3 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.8 GO:0038191 neuropilin binding(GO:0038191)
0.0 1.5 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.1 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.0 0.2 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.2 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 1.0 GO:0005549 odorant binding(GO:0005549)
0.0 0.2 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.4 GO:0015180 L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.0 0.5 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.3 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.0 0.1 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.0 0.3 GO:1901611 phosphatidylglycerol binding(GO:1901611)
0.0 0.1 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.0 0.1 GO:0015065 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0 0.6 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.3 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 0.3 GO:0008429 phosphatidylethanolamine binding(GO:0008429) oligosaccharide binding(GO:0070492)
0.0 0.4 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.6 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.6 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.2 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.2 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.3 GO:0050700 CARD domain binding(GO:0050700)
0.0 1.8 GO:0030507 spectrin binding(GO:0030507)
0.0 0.3 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.7 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.3 GO:0070513 death domain binding(GO:0070513)
0.0 0.2 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.0 1.4 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.2 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.1 GO:0015639 cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.0 0.2 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.2 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.3 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 1.0 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.3 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.1 GO:0003692 left-handed Z-DNA binding(GO:0003692)
0.0 0.1 GO:0015410 manganese-transporting ATPase activity(GO:0015410)
0.0 0.1 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.3 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.2 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.2 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.2 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.3 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.6 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.3 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.2 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.5 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.1 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.0 0.1 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0 0.1 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.0 0.3 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.2 GO:0043495 protein anchor(GO:0043495)
0.0 0.2 GO:0019825 oxygen binding(GO:0019825)
0.0 0.3 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.2 GO:0019865 immunoglobulin binding(GO:0019865)
0.0 0.1 GO:0033142 progesterone receptor binding(GO:0033142)
0.0 0.1 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.0 0.1 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.1 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 0.1 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.0 PID ARF6 PATHWAY Arf6 signaling events
0.0 1.2 PID CONE PATHWAY Visual signal transduction: Cones
0.0 1.0 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 1.0 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.9 PID ARF 3PATHWAY Arf1 pathway
0.0 1.3 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.7 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 1.0 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.9 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.5 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 1.0 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 1.2 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 1.0 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 1.0 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 0.3 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.2 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.9 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.4 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.2 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 0.4 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.4 PID FGF PATHWAY FGF signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1 3.6 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 1.6 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 2.3 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 1.0 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.6 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 1.4 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 1.1 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 1.6 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.4 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.5 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.7 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.3 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.3 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.2 REACTOME FGFR1 LIGAND BINDING AND ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.0 1.0 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.4 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.5 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.3 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 1.0 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 1.9 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.3 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.3 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.4 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 1.7 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.0 0.4 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.5 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.1 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.1 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.5 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.4 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.5 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.7 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.2 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.2 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.2 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.2 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.1 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.2 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.4 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.1 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 0.2 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.1 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.3 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein