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12D miR HR13_24

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Results for Nr1i2

Z-value: 0.83

Motif logo

Transcription factors associated with Nr1i2

Gene Symbol Gene ID Gene Info
ENSMUSG00000022809.4 nuclear receptor subfamily 1, group I, member 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nr1i2mm10_v2_chr16_-_38294774_38294838-0.422.0e-01Click!

Activity profile of Nr1i2 motif

Sorted Z-values of Nr1i2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr8_-_68121527 0.90 ENSMUST00000178529.1
predicted gene, 21807
chr15_+_85510812 0.62 ENSMUST00000079690.2
predicted pseudogene 4825
chr9_+_65630552 0.57 ENSMUST00000055844.8
RNA binding protein with multiple splicing 2
chr9_+_45055211 0.51 ENSMUST00000114663.2
myelin protein zero-like 3
chr1_+_72824482 0.50 ENSMUST00000047328.4
insulin-like growth factor binding protein 2
chr3_-_94436574 0.49 ENSMUST00000029787.4
ornithine decarboxylase antizyme 3
chr7_-_14562171 0.48 ENSMUST00000181796.1
vomeronasal 1 receptor 90
chr10_-_24101951 0.48 ENSMUST00000170267.1
trace amine-associated receptor 8C
chr13_+_44729794 0.46 ENSMUST00000172830.1
jumonji, AT rich interactive domain 2
chr12_-_27342696 0.45 ENSMUST00000079063.5
SRY-box containing gene 11
chr7_+_121707189 0.40 ENSMUST00000065310.2
RIKEN cDNA 1700069B07 gene
chr1_+_87264345 0.39 ENSMUST00000118687.1
ENSMUST00000027472.6
EF hand domain containing 1
chr16_-_44333135 0.38 ENSMUST00000047446.6
SID1 transmembrane family, member 1
chr15_-_98195542 0.38 ENSMUST00000165379.1
ENSMUST00000142443.1
olfactory receptor 288
chr11_+_42419729 0.38 ENSMUST00000007797.4
gamma-aminobutyric acid (GABA) A receptor, subunit beta 2
chr7_-_141429433 0.37 ENSMUST00000124444.1
cell cycle exit and neuronal differentiation 1
chr7_-_4778141 0.37 ENSMUST00000094892.5
interleukin 11
chr3_+_96525163 0.37 ENSMUST00000049208.9
hemochromatosis type 2 (juvenile) (human homolog)
chr10_+_34389974 0.36 ENSMUST00000105511.1
collagen, type X, alpha 1
chr16_-_44332925 0.35 ENSMUST00000136381.1
SID1 transmembrane family, member 1
chr1_+_135232045 0.35 ENSMUST00000110798.3
predicted gene 4204
chr4_+_104367549 0.35 ENSMUST00000106830.2
disabled 1
chr14_-_87141114 0.34 ENSMUST00000168889.1
diaphanous homolog 3 (Drosophila)
chr7_-_141429351 0.34 ENSMUST00000164387.1
ENSMUST00000137488.1
ENSMUST00000084436.3
cell cycle exit and neuronal differentiation 1
chr1_+_45795485 0.34 ENSMUST00000147308.1
WD repeat domain 75
chr1_-_14755966 0.34 ENSMUST00000027062.5
musculin
chr8_-_70120816 0.33 ENSMUST00000002412.8
neurocan
chr15_-_79285502 0.33 ENSMUST00000165408.1
BAI1-associated protein 2-like 2
chr16_+_21891969 0.33 ENSMUST00000042065.6
mitogen-activated protein kinase kinase kinase 13
chr4_+_54945038 0.32 ENSMUST00000133895.1
zinc finger protein 462
chr17_+_47505073 0.32 ENSMUST00000183210.1
cyclin D3
chr17_-_7385305 0.31 ENSMUST00000070059.3
predicted gene 9992
chr3_+_146149829 0.31 ENSMUST00000011152.7
mucolipin 2
chr4_-_43653542 0.31 ENSMUST00000084646.4
sperm associated antigen 8
chr14_+_47001336 0.30 ENSMUST00000125113.1
sterile alpha motif domain containing 4
chr6_-_113600645 0.30 ENSMUST00000035870.4
Fancd2 opposite strand
chr17_-_45474839 0.30 ENSMUST00000024731.8
spermatogenesis associated, serine-rich 1
chr1_+_134193432 0.29 ENSMUST00000038445.6
myosin binding protein H
chr10_-_80813486 0.29 ENSMUST00000181039.1
ENSMUST00000180438.1
junctional sarcoplasmic reticulum protein 1
chr15_+_78430086 0.29 ENSMUST00000162808.1
potassium channel tetramerisation domain containing 17
chr9_-_29412204 0.29 ENSMUST00000115237.1
neurotrimin
chr19_-_24901309 0.29 ENSMUST00000058600.2
forkhead box D4
chr7_-_46667375 0.28 ENSMUST00000107669.2
tryptophan hydroxylase 1
chr1_-_21961581 0.28 ENSMUST00000029667.6
ENSMUST00000173058.1
ENSMUST00000173404.1
potassium voltage-gated channel, subfamily Q, member 5
chr3_+_129532386 0.28 ENSMUST00000071402.2
ELOVL family member 6, elongation of long chain fatty acids (yeast)
chr2_-_174853355 0.28 ENSMUST00000149377.1
predicted gene 14618
chr19_-_4477447 0.28 ENSMUST00000059295.3
synaptotagmin XII
chr12_+_72441933 0.28 ENSMUST00000161284.1
leucine rich repeat containing 9
chr7_+_5056706 0.27 ENSMUST00000144802.1
coiled-coil domain containing 106
chr8_-_122460666 0.27 ENSMUST00000006762.5
snail homolog 3 (Drosophila)
chr5_-_28210022 0.27 ENSMUST00000118882.1
canopy 1 homolog (zebrafish)
chr15_-_103310425 0.27 ENSMUST00000079824.4
G protein-coupled receptor 84
chr6_+_40110251 0.27 ENSMUST00000061740.7
transmembrane protein 178B
chr4_-_137785371 0.27 ENSMUST00000133473.1
alkaline phosphatase, liver/bone/kidney
chr17_-_47421873 0.26 ENSMUST00000073143.6
RIKEN cDNA 1700001C19 gene
chr17_-_35909626 0.26 ENSMUST00000141132.1
alpha tubulin acetyltransferase 1
chr6_+_21986887 0.26 ENSMUST00000151315.1
cadherin-like and PC-esterase domain containing 1
chr2_+_173153048 0.26 ENSMUST00000029017.5
phosphoenolpyruvate carboxykinase 1, cytosolic
chr16_-_4523056 0.25 ENSMUST00000090500.3
ENSMUST00000023161.7
sarcalumenin
chr3_+_153973436 0.25 ENSMUST00000089948.5
solute carrier family 44, member 5
chr6_+_113531675 0.25 ENSMUST00000036340.5
ENSMUST00000101051.2
Fanconi anemia, complementation group D2
chr17_+_55445375 0.25 ENSMUST00000133899.1
ENSMUST00000086878.3
beta galactoside alpha 2,6 sialyltransferase 2
chr19_+_56548254 0.25 ENSMUST00000071423.5
NHL repeat containing 2
chr11_+_69125896 0.25 ENSMUST00000021268.2
arachidonate lipoxygenase 3
chr6_-_142571303 0.25 ENSMUST00000032374.7
potassium inwardly-rectifying channel, subfamily J, member 8
chr5_-_99037342 0.25 ENSMUST00000161490.1
protein kinase, cGMP-dependent, type II
chr18_-_61036189 0.25 ENSMUST00000025521.8
caudal type homeobox 1
chr4_+_126556994 0.25 ENSMUST00000147675.1
claspin
chr1_+_87470258 0.24 ENSMUST00000027476.4
RIKEN cDNA 3110079O15 gene
chr2_+_112265809 0.24 ENSMUST00000110991.2
solute carrier family 12, member 6
chr4_+_126556935 0.24 ENSMUST00000048391.8
claspin
chr8_-_72435043 0.24 ENSMUST00000109974.1
calreticulin 3
chr11_-_79059872 0.24 ENSMUST00000141409.1
kinase suppressor of ras 1
chr6_-_120364344 0.23 ENSMUST00000146667.1
coiled-coil domain containing 77
chr9_-_21963568 0.23 ENSMUST00000006397.5
erythropoietin receptor
chr11_+_115334731 0.23 ENSMUST00000106543.1
ENSMUST00000019006.4
otopetrin 3
chr7_-_126414855 0.23 ENSMUST00000032968.5
CD19 antigen
chr11_+_7063423 0.23 ENSMUST00000020706.4
adenylate cyclase 1
chr7_-_100514800 0.22 ENSMUST00000054923.7
DnaJ (Hsp40) related, subfamily B, member 13
chr2_+_173022360 0.22 ENSMUST00000173997.1
RNA binding motif protein 38
chr8_-_105471481 0.22 ENSMUST00000014990.6
tubulin polymerization-promoting protein family member 3
chr12_+_37241633 0.22 ENSMUST00000049874.7
alkylglycerol monooxygenase
chr9_-_54661666 0.22 ENSMUST00000128624.1
acyl-CoA synthetase bubblegum family member 1
chr7_+_5056856 0.22 ENSMUST00000131368.1
ENSMUST00000123956.1
coiled-coil domain containing 106
chr10_-_78464853 0.22 ENSMUST00000105385.1
pyridoxal (pyridoxine, vitamin B6) kinase
chr1_+_9547948 0.22 ENSMUST00000144177.1
alcohol dehydrogenase, iron containing, 1
chr10_+_128194631 0.22 ENSMUST00000123291.1
glutaminase 2 (liver, mitochondrial)
chr12_+_72441852 0.22 ENSMUST00000162159.1
leucine rich repeat containing 9
chr7_-_46667303 0.21 ENSMUST00000168335.1
tryptophan hydroxylase 1
chr18_-_66860458 0.21 ENSMUST00000057942.2
melanocortin 4 receptor
chr9_+_31280525 0.21 ENSMUST00000117389.1
PR domain containing 10
chr9_-_65422773 0.21 ENSMUST00000065894.5
solute carrier family 51, beta subunit
chr17_-_36867187 0.21 ENSMUST00000025329.6
ENSMUST00000174195.1
tripartite motif-containing 15
chr17_-_12909912 0.21 ENSMUST00000163394.1
poly(A)-specific ribonuclease (PARN)-like domain containing 1
chr2_+_148395369 0.21 ENSMUST00000109962.2
ENSMUST00000047292.2
somatostatin receptor 4
chr3_+_98013503 0.21 ENSMUST00000079812.6
notch 2
chr5_-_99037035 0.21 ENSMUST00000031277.6
protein kinase, cGMP-dependent, type II
chr1_-_79858627 0.20 ENSMUST00000027467.4
serine (or cysteine) peptidase inhibitor, clade E, member 2
chr4_+_124885799 0.20 ENSMUST00000149146.1
Eph receptor A10
chr6_-_59426279 0.20 ENSMUST00000051065.4
GPRIN family member 3
chr2_-_12301914 0.20 ENSMUST00000028106.4
integrin alpha 8
chr12_+_37241729 0.20 ENSMUST00000160768.1
alkylglycerol monooxygenase
chr2_+_22895482 0.20 ENSMUST00000053729.7
prenyl (solanesyl) diphosphate synthase, subunit 1
chr7_+_112679327 0.20 ENSMUST00000106638.2
TEA domain family member 1
chr16_-_44139630 0.20 ENSMUST00000137557.1
ENSMUST00000147025.1
ATPase, H+ transporting, lysosomal V1 subunit A
chr2_+_174760781 0.20 ENSMUST00000140908.1
endothelin 3
chrX_-_166585679 0.20 ENSMUST00000000412.2
EGF-like-domain, multiple 6
chr9_+_78051938 0.20 ENSMUST00000024104.7
glial cells missing homolog 1 (Drosophila)
chr15_-_102366314 0.20 ENSMUST00000078508.5
Sp7 transcription factor 7
chr7_+_101818306 0.20 ENSMUST00000008090.9
paired-like homeobox 2a
chr2_+_130012336 0.19 ENSMUST00000110299.2
transglutaminase 3, E polypeptide
chr17_-_78985428 0.19 ENSMUST00000118991.1
protein kinase D3
chr9_-_98955302 0.19 ENSMUST00000181706.1
forkhead box L2 opposite strand transcript
chr2_+_158502633 0.19 ENSMUST00000109484.1
adipogenin
chr1_+_156838915 0.19 ENSMUST00000111720.1
angiopoietin-like 1
chr18_+_34542313 0.19 ENSMUST00000012426.2
wingless-related MMTV integration site 8A
chr5_+_107431541 0.18 ENSMUST00000166599.1
lysophosphatidylcholine acyltransferase 2B
chr7_-_45179539 0.18 ENSMUST00000179443.1
predicted gene 581
chr19_+_41582370 0.18 ENSMUST00000172371.1
predicted gene 340
chr1_-_22315792 0.18 ENSMUST00000164877.1
regulating synaptic membrane exocytosis 1
chr5_-_145469723 0.18 ENSMUST00000031633.4
cytochrome P450, family 3, subfamily a, polypeptide 16
chr9_-_106656081 0.18 ENSMUST00000023959.7
glutamate receptor, metabotropic 2
chr4_-_82705735 0.18 ENSMUST00000155821.1
nuclear factor I/B
chr6_-_23650206 0.18 ENSMUST00000115354.1
ring finger protein 133
chr1_+_74791516 0.18 ENSMUST00000006718.8
wingless related MMTV integration site 10a
chr2_+_150190393 0.18 ENSMUST00000109929.2
predicted gene 14139
chr15_+_74563738 0.18 ENSMUST00000170845.1
brain-specific angiogenesis inhibitor 1
chr11_+_75510077 0.17 ENSMUST00000042972.6
Rab interacting lysosomal protein
chr6_+_90333270 0.17 ENSMUST00000164761.1
ENSMUST00000046128.9
urocanase domain containing 1
chr3_-_115888086 0.17 ENSMUST00000067500.5
RIKEN cDNA A930005H10 gene
chr17_-_32917048 0.17 ENSMUST00000054174.7
cytochrome P450, family 4, subfamily f, polypeptide 14
chr4_-_144721404 0.17 ENSMUST00000036876.7
predicted gene 13178
chr8_-_105568298 0.17 ENSMUST00000005849.5
agouti related protein
chrX_-_167855061 0.17 ENSMUST00000112146.1
FERM and PDZ domain containing 4
chrX_+_9885622 0.16 ENSMUST00000067529.2
ENSMUST00000086165.3
synaptotagmin-like 5
chr1_+_75549581 0.16 ENSMUST00000154101.1
solute carrier family 4 (anion exchanger), member 3
chr7_-_109439076 0.16 ENSMUST00000106745.2
ENSMUST00000090414.4
serine/threonine kinase 33
chr11_+_76902152 0.16 ENSMUST00000102495.1
transmembrane and immunoglobulin domain containing 1
chr9_+_108080436 0.16 ENSMUST00000035211.7
ENSMUST00000162886.1
macrophage stimulating 1 (hepatocyte growth factor-like)
chr19_+_8591254 0.16 ENSMUST00000010251.3
ENSMUST00000170817.1
solute carrier family 22 (organic anion transporter), member 8
chr10_+_79881023 0.16 ENSMUST00000166201.1
proteinase 3
chr7_+_3303643 0.16 ENSMUST00000172109.1
protein kinase C, gamma
chr17_+_49615104 0.16 ENSMUST00000162854.1
kinesin family member 6
chr12_-_11150305 0.16 ENSMUST00000055673.1
potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3
chr1_+_15312452 0.16 ENSMUST00000171715.1
potassium voltage gated channel, Shab-related subfamily, member 2
chrX_-_8145679 0.16 ENSMUST00000115619.1
ENSMUST00000115617.3
ENSMUST00000040010.3
RNA binding motif protein 3
chr16_-_14291355 0.15 ENSMUST00000090287.3
myosin, heavy polypeptide 11, smooth muscle
chr17_+_84683131 0.15 ENSMUST00000171915.1
ATP-binding cassette, sub-family G (WHITE), member 8
chr6_-_23650298 0.15 ENSMUST00000063548.3
ring finger protein 133
chr9_+_53537021 0.15 ENSMUST00000035850.7
nuclear protein in the AT region
chr13_-_93144557 0.15 ENSMUST00000062122.3
cardiomyopathy associated 5
chr11_+_49340534 0.15 ENSMUST00000062719.1
olfactory receptor 1390
chr1_-_46030437 0.15 ENSMUST00000171707.1
ENSMUST00000167676.1
ENSMUST00000051224.1
predicted gene 4776
chr3_+_68869563 0.15 ENSMUST00000054551.2
RIKEN cDNA 1110032F04 gene
chr11_-_3722189 0.15 ENSMUST00000102950.3
ENSMUST00000101632.3
oxysterol binding protein 2
chr16_+_43363855 0.15 ENSMUST00000156367.1
zinc finger and BTB domain containing 20
chr4_-_41275091 0.15 ENSMUST00000030143.6
ENSMUST00000108068.1
ubiquitin-associated protein 2
chr1_-_12991109 0.15 ENSMUST00000115403.2
ENSMUST00000115402.1
solute carrier organic anion transporter family, member 5A1
chr2_+_110017879 0.15 ENSMUST00000150183.2
coiled-coil domain containing 34
chr16_-_19883873 0.15 ENSMUST00000100083.3
RIKEN cDNA A930003A15 gene
chr16_+_91269759 0.14 ENSMUST00000056882.5
oligodendrocyte transcription factor 1
chr14_-_21848924 0.14 ENSMUST00000124549.1
catechol-O-methyltransferase domain containing 1
chr6_+_40491238 0.14 ENSMUST00000064932.4
taste receptor, type 2, member 137
chr1_+_127729405 0.14 ENSMUST00000038006.6
amino carboxymuconate semialdehyde decarboxylase
chr1_-_191907527 0.14 ENSMUST00000069573.5
RIKEN cDNA 1700034H15 gene
chr4_-_108625216 0.14 ENSMUST00000166069.1
predicted gene, 20731
chr6_+_63255971 0.14 ENSMUST00000159561.1
ENSMUST00000095852.3
glutamate receptor, ionotropic, delta 2
chr17_-_25880236 0.14 ENSMUST00000176696.1
ENSMUST00000095487.5
WAP, FS, Ig, KU, and NTR-containing protein 1
chr2_+_152911311 0.14 ENSMUST00000028970.7
myosin, light polypeptide kinase 2, skeletal muscle
chr3_+_108256926 0.14 ENSMUST00000090569.5
proteasome (prosome, macropain) subunit, alpha type 5
chr11_+_95837216 0.14 ENSMUST00000107712.1
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
chr4_+_33132552 0.14 ENSMUST00000182186.1
gamma-aminobutyric acid (GABA) C receptor, subunit rho 1
chr4_-_141416002 0.13 ENSMUST00000006378.2
ENSMUST00000105788.1
chloride channel Kb
chr2_-_110362985 0.13 ENSMUST00000099626.3
fin bud initiation factor homolog (zebrafish)
chr4_-_153975038 0.13 ENSMUST00000030893.2
DNA fragmentation factor, beta subunit
chr12_-_3426700 0.13 ENSMUST00000180149.1
RIKEN cDNA 1110002L01 gene
chr18_+_69346143 0.13 ENSMUST00000114980.1
transcription factor 4
chr5_-_28210168 0.13 ENSMUST00000117098.1
canopy 1 homolog (zebrafish)
chr7_-_57387172 0.13 ENSMUST00000068911.6
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 3
chr10_+_59403644 0.13 ENSMUST00000009790.7
phospholipase A2, group XIIB
chr16_+_4036942 0.13 ENSMUST00000137748.1
ENSMUST00000006136.4
ENSMUST00000157044.1
ENSMUST00000120009.1
deoxyribonuclease I
chr2_+_147364989 0.13 ENSMUST00000109968.2
paired box gene 1
chr2_+_155611175 0.13 ENSMUST00000092995.5
myosin, heavy chain 7B, cardiac muscle, beta
chr10_+_52690496 0.13 ENSMUST00000105473.2
solute carrier family 35, member F1
chr2_+_136057927 0.13 ENSMUST00000057503.6
lysosomal-associated membrane protein family, member 5
chr4_-_135573623 0.13 ENSMUST00000105855.1
grainyhead-like 3 (Drosophila)
chr12_+_37242030 0.13 ENSMUST00000160390.1
alkylglycerol monooxygenase
chr11_+_70054334 0.13 ENSMUST00000018699.6
ENSMUST00000108585.2
asialoglycoprotein receptor 1
chr6_-_28447180 0.12 ENSMUST00000174194.1
paired box gene 4
chr4_+_84884366 0.12 ENSMUST00000102819.3
centlein, centrosomal protein
chr13_-_98815408 0.12 ENSMUST00000040340.8
ENSMUST00000099277.4
ENSMUST00000179563.1
ENSMUST00000109403.1
FCH domain only 2
chr1_+_131750485 0.12 ENSMUST00000147800.1
solute carrier family 26, member 9
chr5_+_31094984 0.12 ENSMUST00000066505.1
predicted gene 9924
chr1_+_134037490 0.12 ENSMUST00000162779.1
fibromodulin
chr2_+_110017806 0.12 ENSMUST00000028580.5
coiled-coil domain containing 34
chr10_+_39899304 0.12 ENSMUST00000181590.1
RIKEN cDNA 4930547M16 gene
chr7_-_131327325 0.12 ENSMUST00000033146.7
RIKEN cDNA 1700007K09 gene
chr16_+_34784917 0.12 ENSMUST00000023538.8
myosin, light polypeptide kinase
chr13_+_102693596 0.12 ENSMUST00000172138.1
CD180 antigen
chr1_-_139781236 0.12 ENSMUST00000027612.8
ENSMUST00000111989.2
ENSMUST00000111986.2
predicted gene 4788

Network of associatons between targets according to the STRING database.

First level regulatory network of Nr1i2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0021933 radial glia guided migration of cerebellar granule cell(GO:0021933)
0.2 0.5 GO:2001226 negative regulation of chloride transport(GO:2001226)
0.1 0.5 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.1 0.3 GO:0021589 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)
0.1 0.4 GO:0061386 closure of optic fissure(GO:0061386)
0.1 0.3 GO:0071929 alpha-tubulin acetylation(GO:0071929)
0.1 0.3 GO:0006114 glycerol biosynthetic process(GO:0006114) positive regulation of transcription from RNA polymerase II promoter in response to acidic pH(GO:0061402)
0.1 0.3 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.1 0.7 GO:0033227 dsRNA transport(GO:0033227)
0.1 0.2 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.1 0.2 GO:0042823 pyridoxal phosphate biosynthetic process(GO:0042823)
0.1 0.2 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.1 0.2 GO:1990705 intrahepatic bile duct development(GO:0035622) cholangiocyte proliferation(GO:1990705)
0.1 0.2 GO:0021623 oculomotor nerve morphogenesis(GO:0021622) oculomotor nerve formation(GO:0021623)
0.1 0.2 GO:0035585 calcium-mediated signaling using extracellular calcium source(GO:0035585)
0.1 0.2 GO:0070676 intralumenal vesicle formation(GO:0070676)
0.1 0.3 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.1 0.5 GO:1901162 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.1 0.2 GO:0042939 glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
0.1 0.2 GO:1904730 negative regulation of intestinal phytosterol absorption(GO:0010949) negative regulation of intestinal cholesterol absorption(GO:0045796) intestinal phytosterol absorption(GO:0060752) negative regulation of intestinal lipid absorption(GO:1904730)
0.1 0.2 GO:2000721 positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.1 0.3 GO:0051121 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.2 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0 0.1 GO:0072289 metanephric nephron tubule formation(GO:0072289)
0.0 0.3 GO:0006543 glutamine catabolic process(GO:0006543)
0.0 0.2 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
0.0 0.5 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.2 GO:0006548 histidine catabolic process(GO:0006548)
0.0 0.6 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0 0.5 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 0.2 GO:1901252 regulation of intracellular transport of viral material(GO:1901252)
0.0 0.2 GO:0061110 dense core granule biogenesis(GO:0061110)
0.0 0.1 GO:0071476 cellular hypotonic response(GO:0071476)
0.0 0.1 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.0 0.1 GO:0060447 bud outgrowth involved in lung branching(GO:0060447)
0.0 0.3 GO:0014874 response to stimulus involved in regulation of muscle adaptation(GO:0014874)
0.0 0.1 GO:1900157 regulation of bone mineralization involved in bone maturation(GO:1900157)
0.0 0.1 GO:0015680 intracellular copper ion transport(GO:0015680)
0.0 0.3 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.0 0.1 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.0 0.5 GO:0046485 ether lipid metabolic process(GO:0046485)
0.0 0.2 GO:0032423 regulation of mismatch repair(GO:0032423)
0.0 0.1 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
0.0 0.2 GO:0009946 proximal/distal axis specification(GO:0009946)
0.0 0.2 GO:0070885 negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.0 0.1 GO:1902202 proteoglycan catabolic process(GO:0030167) regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.0 0.1 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.0 0.1 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.0 0.1 GO:0061303 cornea development in camera-type eye(GO:0061303)
0.0 0.4 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.0 0.1 GO:0032971 regulation of muscle filament sliding(GO:0032971)
0.0 0.2 GO:0089700 protein kinase D signaling(GO:0089700)
0.0 0.2 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.2 GO:0060050 positive regulation of protein glycosylation(GO:0060050)
0.0 0.1 GO:0036023 limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023)
0.0 0.1 GO:2001160 regulation of histone H3-K79 methylation(GO:2001160)
0.0 0.1 GO:0061056 sclerotome development(GO:0061056)
0.0 0.3 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.0 0.1 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.0 0.4 GO:0071420 cellular response to histamine(GO:0071420)
0.0 0.2 GO:0098915 membrane repolarization during ventricular cardiac muscle cell action potential(GO:0098915)
0.0 0.1 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.7 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.3 GO:0034625 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.1 GO:0035902 response to immobilization stress(GO:0035902)
0.0 0.4 GO:0016540 protein autoprocessing(GO:0016540)
0.0 0.6 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0 0.1 GO:0003218 cardiac left ventricle formation(GO:0003218)
0.0 0.3 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.2 GO:0008343 adult feeding behavior(GO:0008343) positive regulation of feeding behavior(GO:2000253)
0.0 0.1 GO:0071798 response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799)
0.0 0.1 GO:0071918 urea transmembrane transport(GO:0071918)
0.0 0.3 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.0 0.1 GO:0016103 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.0 0.0 GO:1901420 negative regulation of response to alcohol(GO:1901420)
0.0 0.2 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.3 GO:2000821 regulation of grooming behavior(GO:2000821)
0.0 0.2 GO:0060763 mammary duct terminal end bud growth(GO:0060763)
0.0 0.1 GO:0021780 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.0 0.1 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.0 0.2 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.0 0.1 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.0 0.1 GO:0045794 negative regulation of cell volume(GO:0045794)
0.0 0.1 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.0 0.0 GO:1901662 menaquinone metabolic process(GO:0009233) phylloquinone metabolic process(GO:0042374) phylloquinone catabolic process(GO:0042376) quinone catabolic process(GO:1901662)
0.0 0.1 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.0 0.1 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0 0.1 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 0.1 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)
0.0 0.0 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.0 0.1 GO:2001023 regulation of response to drug(GO:2001023)
0.0 0.1 GO:0006172 ADP biosynthetic process(GO:0006172)
0.0 0.1 GO:1904861 excitatory synapse assembly(GO:1904861)
0.0 0.2 GO:0061032 visceral serous pericardium development(GO:0061032)
0.0 0.1 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.2 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
0.0 0.1 GO:0003100 regulation of systemic arterial blood pressure by endothelin(GO:0003100) vein smooth muscle contraction(GO:0014826)
0.0 0.1 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.2 GO:0006968 cellular defense response(GO:0006968)
0.0 0.2 GO:0014883 transition between fast and slow fiber(GO:0014883)
0.0 0.2 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.1 GO:1900170 negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
0.0 0.1 GO:0010747 positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747)
0.0 0.1 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.0 0.1 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0 0.3 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.2 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.0 0.2 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 0.1 GO:0038044 transforming growth factor-beta secretion(GO:0038044)
0.0 0.1 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.0 0.3 GO:0060314 regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314)
0.0 0.1 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.0 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.0 0.1 GO:0021546 rhombomere development(GO:0021546)
0.0 0.3 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.1 GO:1903351 response to dopamine(GO:1903350) cellular response to dopamine(GO:1903351)
0.0 0.0 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.1 0.5 GO:0097427 microtubule bundle(GO:0097427)
0.1 0.2 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.1 0.2 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.2 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 0.1 GO:0098835 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835)
0.0 0.2 GO:0098831 presynaptic active zone cytoplasmic component(GO:0098831)
0.0 0.8 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.3 GO:0071439 clathrin complex(GO:0071439)
0.0 0.1 GO:0018444 translation release factor complex(GO:0018444)
0.0 0.1 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.0 0.1 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 0.6 GO:0032982 myosin filament(GO:0032982)
0.0 0.2 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.0 0.2 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.1 GO:0005745 m-AAA complex(GO:0005745)
0.0 0.1 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.0 0.3 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.2 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.1 GO:0036019 endolysosome(GO:0036019)
0.0 0.2 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.1 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.5 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.1 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.3 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.0 0.1 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.0 0.1 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.1 GO:0036128 CatSper complex(GO:0036128)
0.0 0.1 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0 0.1 GO:0001520 outer dense fiber(GO:0001520)
0.0 0.0 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.3 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0050479 glyceryl-ether monooxygenase activity(GO:0050479)
0.1 0.7 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.1 0.5 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.1 0.5 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.1 0.3 GO:0052870 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871)
0.1 0.5 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.1 0.2 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.1 0.5 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.1 0.2 GO:0035827 rubidium ion transmembrane transporter activity(GO:0035827)
0.1 0.2 GO:0031403 lithium ion binding(GO:0031403)
0.1 0.4 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 0.2 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.1 0.2 GO:0050347 trans-hexaprenyltranstransferase activity(GO:0000010) trans-octaprenyltranstransferase activity(GO:0050347)
0.1 0.5 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 0.3 GO:0004966 galanin receptor activity(GO:0004966)
0.1 0.2 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
0.1 0.4 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.1 0.2 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.4 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.3 GO:0004359 glutaminase activity(GO:0004359)
0.0 0.2 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.0 0.3 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.2 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 0.3 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.2 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0 0.5 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.1 GO:0050051 alkane 1-monooxygenase activity(GO:0018685) leukotriene-B4 20-monooxygenase activity(GO:0050051)
0.0 0.2 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.1 GO:0051373 FATZ binding(GO:0051373)
0.0 0.4 GO:0098821 BMP binding(GO:0036122) BMP receptor activity(GO:0098821)
0.0 0.1 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.0 0.2 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0 0.1 GO:0043682 copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682)
0.0 0.2 GO:0050649 testosterone 6-beta-hydroxylase activity(GO:0050649)
0.0 0.6 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.2 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.3 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.2 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.0 0.2 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640)
0.0 0.1 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.2 GO:0015651 quaternary ammonium group transmembrane transporter activity(GO:0015651)
0.0 0.1 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.1 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.1 GO:0008527 taste receptor activity(GO:0008527)
0.0 0.1 GO:0051538 3 iron, 4 sulfur cluster binding(GO:0051538)
0.0 0.3 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.2 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.5 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.1 GO:0038051 glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.3 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.2 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.0 0.3 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.9 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.3 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.3 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.1 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 0.2 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.0 GO:0005502 11-cis retinal binding(GO:0005502)
0.0 0.3 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.2 GO:0005372 water transmembrane transporter activity(GO:0005372)
0.0 0.0 GO:0016748 succinyltransferase activity(GO:0016748)
0.0 0.1 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.2 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.1 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0 0.2 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.5 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.1 GO:0035014 phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.0 0.0 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.1 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.9 PID ATR PATHWAY ATR signaling pathway
0.0 0.2 PID LPA4 PATHWAY LPA4-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.6 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.3 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.2 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 0.5 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.2 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.3 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.5 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.2 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.2 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.1 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 0.4 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.1 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.1 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.3 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.6 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.1 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint