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12D miR HR13_24

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Results for Tfcp2l1

Z-value: 0.57

Motif logo

Transcription factors associated with Tfcp2l1

Gene Symbol Gene ID Gene Info
ENSMUSG00000026380.9 transcription factor CP2-like 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Tfcp2l1mm10_v2_chr1_+_118627943_1186279510.225.1e-01Click!

Activity profile of Tfcp2l1 motif

Sorted Z-values of Tfcp2l1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr16_-_22161450 1.00 ENSMUST00000115379.1
insulin-like growth factor 2 mRNA binding protein 2
chr7_-_141117772 0.91 ENSMUST00000067836.7
anoctamin 9
chr7_-_100656953 0.88 ENSMUST00000107046.1
ENSMUST00000107045.1
ENSMUST00000139708.1
pleckstrin homology domain containing, family B (evectins) member 1
chr1_-_184033998 0.84 ENSMUST00000050306.5
RIKEN cDNA 1700056E22 gene
chr3_+_106486009 0.66 ENSMUST00000183271.1
ENSMUST00000061206.3
DENN/MADD domain containing 2D
chr10_-_81291227 0.66 ENSMUST00000045744.6
tight junction protein 3
chrX_+_52791179 0.61 ENSMUST00000101588.1
coiled-coil domain containing 160
chr10_+_43579161 0.51 ENSMUST00000058714.8
CD24a antigen
chr11_-_116238077 0.48 ENSMUST00000037007.3
envoplakin
chr11_-_99986593 0.46 ENSMUST00000105050.2
keratin associated protein 16-1
chr11_-_3452355 0.45 ENSMUST00000064364.2
ENSMUST00000077078.5
ring finger protein 185
chr11_-_105937798 0.45 ENSMUST00000183493.1
cytochrome b-561
chr1_-_124045247 0.43 ENSMUST00000112603.2
dipeptidylpeptidase 10
chr3_-_107518001 0.42 ENSMUST00000169449.1
ENSMUST00000029499.8
solute carrier family 6 (neurotransmitter transporter), member 17
chr4_-_53262547 0.41 ENSMUST00000098075.2
expressed sequence AI427809
chr3_+_103575275 0.40 ENSMUST00000090697.4
synaptotagmin VI
chr2_+_119237351 0.40 ENSMUST00000028783.7
serine protease inhibitor, Kunitz type 1
chr2_+_119237453 0.39 ENSMUST00000110816.1
serine protease inhibitor, Kunitz type 1
chr6_+_97929799 0.38 ENSMUST00000101123.3
microphthalmia-associated transcription factor
chr8_-_72009619 0.37 ENSMUST00000003574.4
cytochrome P450, family 4, subfamily f, polypeptide 18
chr6_-_112946754 0.37 ENSMUST00000113169.2
SLIT-ROBO Rho GTPase activating protein 3
chr1_-_124045523 0.37 ENSMUST00000112606.1
dipeptidylpeptidase 10
chr1_+_184034381 0.35 ENSMUST00000048655.7
dual specificity phosphatase 10
chr5_-_138263942 0.35 ENSMUST00000048421.7
ENSMUST00000164203.1
cDNA sequence BC037034
cDNA sequence BC037034
chr19_-_24477356 0.34 ENSMUST00000099556.1
family with sequence similarity 122, member A
chr5_+_114568016 0.34 ENSMUST00000043650.7
family with sequence similarity 222, member A
chr19_+_6418731 0.34 ENSMUST00000113462.1
ENSMUST00000077182.6
ENSMUST00000113461.1
neurexin II
chr5_-_138264013 0.32 ENSMUST00000161604.1
ENSMUST00000163268.1
cDNA sequence BC037034
cDNA sequence BC037034
chr12_-_4907705 0.31 ENSMUST00000020962.5
UBX domain protein 2A
chr3_+_103575231 0.31 ENSMUST00000121834.1
synaptotagmin VI
chr6_-_13838432 0.30 ENSMUST00000115492.1
G protein-coupled receptor 85
chr5_+_19227046 0.29 ENSMUST00000088516.3
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr13_-_114932035 0.28 ENSMUST00000056117.8
integrin alpha 2
chr19_-_8929323 0.27 ENSMUST00000096242.3
rod outer segment membrane protein 1
chr1_+_5083105 0.27 ENSMUST00000044369.7
ATPase, H+ transporting, lysosomal V1 subunit H
chr10_+_80019621 0.27 ENSMUST00000043311.6
histocompatibility (minor) HA-1
chr2_+_128126030 0.27 ENSMUST00000089634.5
ENSMUST00000019281.7
ENSMUST00000110341.2
ENSMUST00000103211.1
ENSMUST00000103210.1
BCL2-like 11 (apoptosis facilitator)
chr7_-_79743034 0.26 ENSMUST00000032761.7
peroxisomal biogenesis factor 11 alpha
chr4_-_147936713 0.25 ENSMUST00000105712.1
ENSMUST00000019199.7
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
chr3_-_107517321 0.25 ENSMUST00000166892.1
solute carrier family 6 (neurotransmitter transporter), member 17
chr2_-_163750169 0.23 ENSMUST00000017841.3
adenosine deaminase
chr11_+_69088490 0.23 ENSMUST00000021273.6
ENSMUST00000117780.1
vesicle-associated membrane protein 2
chr12_-_4907229 0.22 ENSMUST00000142867.1
UBX domain protein 2A
chr2_+_172549581 0.22 ENSMUST00000030391.2
transcription factor AP-2, gamma
chr5_-_30907692 0.22 ENSMUST00000132034.2
ENSMUST00000132253.2
oligosaccharyltransferase 4 homolog (S. cerevisiae)
chr1_+_40681659 0.21 ENSMUST00000027231.7
solute carrier family 9 (sodium/hydrogen exchanger), member 2
chr2_+_11339461 0.21 ENSMUST00000131188.1
predicted gene 13293
chr1_+_130731963 0.21 ENSMUST00000039323.6
expressed sequence AA986860
chr4_-_133339238 0.20 ENSMUST00000105906.1
WD and tetratricopeptide repeats 1
chr7_-_97332017 0.20 ENSMUST00000139582.2
ubiquitin specific peptidase 35
chr4_-_133339283 0.19 ENSMUST00000043305.7
WD and tetratricopeptide repeats 1
chr12_+_17544873 0.19 ENSMUST00000171737.1
ornithine decarboxylase, structural 1
chr15_+_102977032 0.19 ENSMUST00000001706.6
homeobox C9
chr9_-_54068346 0.18 ENSMUST00000098760.3
tumor necrosis factor, alpha-induced protein 8-like 3
chr9_+_45138437 0.18 ENSMUST00000060125.5
sodium channel, type IV, beta
chr2_-_120085772 0.18 ENSMUST00000134935.1
spectrin beta, non-erythrocytic 5
chr3_+_138860489 0.17 ENSMUST00000121826.1
tetraspanin 5
chr17_+_35823509 0.16 ENSMUST00000173493.1
ENSMUST00000173147.1
ENSMUST00000172846.1
flotillin 1
chr19_+_48206025 0.16 ENSMUST00000078880.5
sortilin-related VPS10 domain containing receptor 3
chr2_+_157424255 0.16 ENSMUST00000029175.7
ENSMUST00000092576.4
Rous sarcoma oncogene
chr7_+_97332311 0.15 ENSMUST00000054107.5
potassium channel tetramerisation domain containing 21
chr16_-_18622403 0.15 ENSMUST00000167388.1
glycoprotein Ib, beta polypeptide
chr19_+_42045792 0.15 ENSMUST00000172244.1
ENSMUST00000081714.4
4-hydroxy-2-oxoglutarate aldolase 1
chr2_-_38714491 0.15 ENSMUST00000028084.4
nuclear receptor subfamily 5, group A, member 1
chr18_-_9450097 0.15 ENSMUST00000053917.4
cyclin Y
chr16_+_18218170 0.15 ENSMUST00000167061.1
predicted gene 7873
chr19_+_4139799 0.14 ENSMUST00000096338.3
G protein-coupled receptor 152
chr14_+_55765956 0.14 ENSMUST00000057569.3
leukotriene B4 receptor 1
chr2_-_26122769 0.14 ENSMUST00000140993.1
ENSMUST00000028300.5
nucleus accumbens associated 2, BEN and BTB (POZ) domain containing
chr5_-_113081579 0.14 ENSMUST00000131708.1
ENSMUST00000117143.1
ENSMUST00000119627.1
crystallin, beta B3
chr17_+_35823230 0.13 ENSMUST00000001569.8
ENSMUST00000174080.1
flotillin 1
chr19_+_8929628 0.13 ENSMUST00000096241.4
echinoderm microtubule associated protein like 3
chr18_+_6765171 0.13 ENSMUST00000097680.5
RAB18, member RAS oncogene family
chr6_+_56832059 0.13 ENSMUST00000031795.7
FK506 binding protein 9
chr9_-_108649349 0.11 ENSMUST00000013338.8
ariadne homolog 2 (Drosophila)
chr11_-_69822144 0.11 ENSMUST00000045771.6
sperm maturation 1
chr17_-_26199008 0.11 ENSMUST00000142410.1
ENSMUST00000120333.1
ENSMUST00000039113.7
protein disulfide isomerase associated 2
chr7_-_25390098 0.11 ENSMUST00000054301.7
lipase, hormone sensitive
chr4_+_118428078 0.10 ENSMUST00000006557.6
ENSMUST00000167636.1
ENSMUST00000102673.4
elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1
chr11_-_109473598 0.10 ENSMUST00000070152.5
solute carrier family 16 (monocarboxylic acid transporters), member 6
chr3_+_95164306 0.09 ENSMUST00000107217.1
ENSMUST00000168321.1
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C
chr5_-_113080566 0.09 ENSMUST00000140352.1
ENSMUST00000076069.6
crystallin, beta B3
chr4_-_124850473 0.09 ENSMUST00000137769.2
RIKEN cDNA 1110065P20 gene
chr15_+_89386827 0.09 ENSMUST00000166926.2
kelch domain containing 7B
chr17_+_35194405 0.08 ENSMUST00000025262.5
lymphotoxin B
chr2_+_91265252 0.07 ENSMUST00000028691.6
ADP-ribosylation factor GTPase activating protein 2
chr2_+_127341630 0.07 ENSMUST00000089673.3
ENSMUST00000179618.1
astacin-like metalloendopeptidase (M12 family)
chr4_-_134012381 0.06 ENSMUST00000176113.1
lin-28 homolog A (C. elegans)
chr9_+_96119362 0.06 ENSMUST00000085217.5
ENSMUST00000122383.1
glycerol kinase 5 (putative)
chr4_-_117887292 0.06 ENSMUST00000150204.1
ENSMUST00000147845.1
ENSMUST00000036380.7
ENSMUST00000136596.1
ATPase, H+ transporting, lysosomal V0 subunit B
chr4_+_125085134 0.06 ENSMUST00000154689.1
ENSMUST00000055213.4
ENSMUST00000106171.2
MYST/Esa1-associated factor 6
chr8_-_17535251 0.06 ENSMUST00000082104.6
CUB and Sushi multiple domains 1
chrX_-_7319291 0.06 ENSMUST00000128319.1
chloride channel 5
chr4_-_135573623 0.06 ENSMUST00000105855.1
grainyhead-like 3 (Drosophila)
chr14_-_55713088 0.05 ENSMUST00000002389.7
transglutaminase 1, K polypeptide
chr3_-_116662643 0.05 ENSMUST00000029570.5
hippocampus abundant gene transcript 1
chr11_-_69878018 0.05 ENSMUST00000178597.1
transmembrane protein 95
chr4_+_43631935 0.05 ENSMUST00000030191.8
natriuretic peptide receptor 2
chr4_-_133967953 0.04 ENSMUST00000102553.4
high mobility group nucleosomal binding domain 2
chr4_+_117126800 0.04 ENSMUST00000062206.2
Tctex1 domain containing 4
chr4_-_117887279 0.04 ENSMUST00000132073.1
ATPase, H+ transporting, lysosomal V0 subunit B
chr4_+_118961578 0.04 ENSMUST00000058651.4
L-amino acid oxidase 1
chr2_-_119229849 0.03 ENSMUST00000110820.2
protein phosphatase 1, regulatory (inhibitor) subunit 14D
chr4_-_133967893 0.03 ENSMUST00000100472.3
ENSMUST00000136327.1
high mobility group nucleosomal binding domain 2
chr5_-_31202215 0.03 ENSMUST00000176245.1
ENSMUST00000177310.1
ENSMUST00000114590.1
zinc finger protein 513
chr11_+_77982710 0.02 ENSMUST00000108360.1
ENSMUST00000049167.7
PHD finger protein 12
chr18_+_37806389 0.01 ENSMUST00000076807.4
protocadherin gamma subfamily A, 9
chr6_-_84593810 0.01 ENSMUST00000077705.3
ENSMUST00000168003.2
cytochrome P450, family 26, subfamily b, polypeptide 1
chr15_+_80711292 0.01 ENSMUST00000067689.7
trinucleotide repeat containing 6b
chr11_+_49513618 0.01 ENSMUST00000060434.2
olfactory receptor 1384
chr1_-_150466165 0.01 ENSMUST00000162367.1
ENSMUST00000161611.1
ENSMUST00000161320.1
ENSMUST00000159035.1
proteoglycan 4 (megakaryocyte stimulating factor, articular superficial zone protein)
chr13_+_80886095 0.01 ENSMUST00000161441.1
arrestin domain containing 3

Network of associatons between targets according to the STRING database.

First level regulatory network of Tfcp2l1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:2001226 negative regulation of chloride transport(GO:2001226)
0.2 0.5 GO:0046013 positive regulation of T cell mediated immune response to tumor cell(GO:0002842) regulation of T cell homeostatic proliferation(GO:0046013)
0.1 0.7 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.1 0.4 GO:0042376 menaquinone metabolic process(GO:0009233) phylloquinone metabolic process(GO:0042374) phylloquinone catabolic process(GO:0042376) quinone catabolic process(GO:1901662)
0.1 0.7 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.1 0.2 GO:0046100 germinal center B cell differentiation(GO:0002314) adenosine catabolic process(GO:0006154) negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) purine nucleobase salvage(GO:0043096) hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101) purine deoxyribonucleoside metabolic process(GO:0046122) negative regulation of mucus secretion(GO:0070256)
0.1 0.3 GO:1902263 apoptotic process involved in embryonic digit morphogenesis(GO:1902263)
0.1 0.3 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.1 0.2 GO:0009446 putrescine biosynthetic process(GO:0009446)
0.1 0.2 GO:0060598 dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis(GO:0060598)
0.1 0.4 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.0 0.3 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.0 0.1 GO:1900477 negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter(GO:1900477)
0.0 0.5 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.0 0.3 GO:0044375 peroxisome membrane biogenesis(GO:0016557) regulation of peroxisome size(GO:0044375)
0.0 0.3 GO:0010694 hypotonic response(GO:0006971) positive regulation of alkaline phosphatase activity(GO:0010694)
0.0 0.8 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0 0.2 GO:0009436 glyoxylate catabolic process(GO:0009436)
0.0 0.2 GO:0043308 eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil degranulation(GO:0043308)
0.0 0.3 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.0 0.2 GO:0051902 negative regulation of mitochondrial depolarization(GO:0051902)
0.0 0.5 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 0.4 GO:0044336 canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
0.0 0.1 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.0 0.6 GO:0031424 keratinization(GO:0031424)
0.0 0.4 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0 0.1 GO:2000360 negative regulation of binding of sperm to zona pellucida(GO:2000360)
0.0 0.2 GO:2000195 negative regulation of female gonad development(GO:2000195)
0.0 0.3 GO:0042297 vocal learning(GO:0042297) imitative learning(GO:0098596)
0.0 0.2 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.4 GO:0007035 vacuolar acidification(GO:0007035)
0.0 0.8 GO:1903078 positive regulation of protein localization to plasma membrane(GO:1903078)
0.0 0.3 GO:0061298 retina vasculature development in camera-type eye(GO:0061298)
0.0 0.2 GO:0060307 regulation of ventricular cardiac muscle cell membrane repolarization(GO:0060307)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
0.1 0.3 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.1 0.2 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.0 0.2 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 0.5 GO:0001533 cornified envelope(GO:0001533)
0.0 0.5 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.0 0.2 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.7 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.3 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.3 GO:0016600 uropod(GO:0001931) flotillin complex(GO:0016600) cell trailing edge(GO:0031254)
0.0 0.5 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.3 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.3 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.1 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.5 GO:0045095 keratin filament(GO:0045095)
0.0 0.1 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.5 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.9 GO:0001750 photoreceptor outer segment(GO:0001750)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
0.1 0.4 GO:0052870 alkane 1-monooxygenase activity(GO:0018685) tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871)
0.1 0.8 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.1 0.3 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.1 0.3 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 0.1 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 0.9 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.2 GO:0032029 myosin tail binding(GO:0032029)
0.0 0.3 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.2 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.0 1.0 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.5 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.7 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.5 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.1 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.0 0.2 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0 0.4 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.4 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.2 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.2 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.2 GO:0071253 connexin binding(GO:0071253)
0.0 0.2 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.2 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.4 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.0 0.7 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.4 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.7 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.0 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.0 0.1 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.9 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.4 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.2 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.4 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.2 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.2 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.3 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins