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12D miR HR13_24

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Results for Dlx5_Dlx4

Z-value: 1.04

Motif logo

Transcription factors associated with Dlx5_Dlx4

Gene Symbol Gene ID Gene Info
ENSMUSG00000029755.9 distal-less homeobox 5
ENSMUSG00000020871.7 distal-less homeobox 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Dlx4mm10_v2_chr11_-_95146263_951462630.831.6e-03Click!
Dlx5mm10_v2_chr6_-_6882068_68820920.352.9e-01Click!

Activity profile of Dlx5_Dlx4 motif

Sorted Z-values of Dlx5_Dlx4 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr8_-_4779513 3.05 ENSMUST00000022945.7
Shc SH2-domain binding protein 1
chr9_-_16378231 2.12 ENSMUST00000082170.5
FAT tumor suppressor homolog 3 (Drosophila)
chr9_+_65890237 2.02 ENSMUST00000045802.6
RIKEN cDNA 2810417H13 gene
chr11_+_115307155 1.98 ENSMUST00000055490.2
otopetrin 2
chr17_+_34039437 1.74 ENSMUST00000131134.1
ENSMUST00000087497.4
ENSMUST00000114255.1
ENSMUST00000114252.1
collagen, type XI, alpha 2
chr7_-_140154712 1.68 ENSMUST00000059241.7
shadow of prion protein
chr10_+_103367748 1.55 ENSMUST00000074204.4
ENSMUST00000179636.1
solute carrier family 6 (neurotransmitter transporter), member 15
chrX_+_73675500 1.54 ENSMUST00000171398.1
solute carrier family 6 (neurotransmitter transporter, creatine), member 8
chr2_-_121235689 1.51 ENSMUST00000142400.1
transformation related protein 53 binding protein 1
chr2_+_118814195 1.45 ENSMUST00000110842.1
kinetochore-localized astrin/SPAG5 binding
chr1_+_139454747 1.33 ENSMUST00000053364.8
ENSMUST00000097554.3
asp (abnormal spindle)-like, microcephaly associated (Drosophila)
chr16_-_45724600 1.32 ENSMUST00000096057.4
transgelin 3
chr2_+_118813995 1.23 ENSMUST00000134661.1
kinetochore-localized astrin/SPAG5 binding
chr13_+_104229366 1.21 ENSMUST00000022227.6
centromere protein K
chr9_+_95857597 1.20 ENSMUST00000034980.7
ataxia telangiectasia and Rad3 related
chr18_+_4993795 1.19 ENSMUST00000153016.1
supervillin
chr2_-_110362985 1.19 ENSMUST00000099626.3
fin bud initiation factor homolog (zebrafish)
chr3_+_9403049 1.15 ENSMUST00000180874.1
ENSMUST00000181331.1
ENSMUST00000181930.1
RIKEN cDNA C030034L19 gene
chr1_-_65123108 1.12 ENSMUST00000050047.3
ENSMUST00000148020.1
RIKEN cDNA D630023F18 gene
chr19_-_32196393 1.10 ENSMUST00000151822.1
sphingomyelin synthase 1
chr2_+_118814237 1.08 ENSMUST00000028803.7
ENSMUST00000126045.1
kinetochore-localized astrin/SPAG5 binding
chrX_-_134111852 1.06 ENSMUST00000033610.6
NADPH oxidase 1
chr16_-_44332925 1.01 ENSMUST00000136381.1
SID1 transmembrane family, member 1
chr4_-_41464816 1.01 ENSMUST00000108055.2
ENSMUST00000154535.1
ENSMUST00000030148.5
kinesin family member 24
chr18_+_4920509 1.01 ENSMUST00000126977.1
supervillin
chr9_-_36726374 0.96 ENSMUST00000172702.2
ENSMUST00000172742.1
ENSMUST00000034625.5
checkpoint kinase 1
chr8_+_116921735 0.96 ENSMUST00000034205.4
centromere protein N
chr16_-_17144415 0.96 ENSMUST00000115709.1
coiled-coil domain containing 116
chr4_+_126556935 0.93 ENSMUST00000048391.8
claspin
chr8_+_85432686 0.93 ENSMUST00000180883.1
RIKEN cDNA 1700051O22 Gene
chr17_-_12868126 0.92 ENSMUST00000089015.3
MAS1 oncogene
chr9_-_86880647 0.92 ENSMUST00000167014.1
synaptosomal-associated protein 91
chr6_-_50456085 0.88 ENSMUST00000146341.1
ENSMUST00000071728.4
oxysterol binding protein-like 3
chr12_-_55014329 0.87 ENSMUST00000172875.1
bromodomain adjacent to zinc finger domain 1A
chr15_+_82256023 0.86 ENSMUST00000143238.1
RIKEN cDNA 1500009C09 gene
chr8_-_70510322 0.85 ENSMUST00000140679.1
ENSMUST00000129909.1
ENSMUST00000081940.4
ubiquitin A-52 residue ribosomal protein fusion product 1
chr9_-_15357692 0.84 ENSMUST00000098979.3
ENSMUST00000161132.1
RIKEN cDNA 5830418K08 gene
chr15_-_76229492 0.83 ENSMUST00000074834.5
plectin
chr18_+_69346143 0.83 ENSMUST00000114980.1
transcription factor 4
chr17_-_24658425 0.83 ENSMUST00000095544.4
neuropeptide W
chr9_+_32224457 0.83 ENSMUST00000183121.1
Rho GTPase activating protein 32
chr2_+_164613519 0.82 ENSMUST00000094346.2
WAP four-disulfide core domain 6B
chr8_+_46010596 0.82 ENSMUST00000110381.2
Lrp2 binding protein
chr2_-_164613600 0.82 ENSMUST00000094351.4
ENSMUST00000109338.1
WAP four-disulfide core domain 8
chr5_-_137858034 0.81 ENSMUST00000110978.2
paired immunoglobin-like type 2 receptor beta 1
chr1_-_134955847 0.77 ENSMUST00000168381.1
protein phosphatase 1, regulatory (inhibitor) subunit 12B
chr2_+_175283298 0.75 ENSMUST00000098998.3
predicted gene 14440
chr14_-_67715585 0.75 ENSMUST00000163100.1
ENSMUST00000132705.1
ENSMUST00000124045.1
cell division cycle associated 2
chrX_+_56786527 0.73 ENSMUST00000144600.1
four and a half LIM domains 1
chr2_-_91950386 0.73 ENSMUST00000111303.1
diacylglycerol kinase zeta
chr17_+_13948373 0.73 ENSMUST00000088809.5
predicted gene 7168
chr19_-_34255325 0.72 ENSMUST00000039631.8
actin, alpha 2, smooth muscle, aorta
chr19_-_55241236 0.71 ENSMUST00000069183.6
guanylate cyclase 2g
chr2_+_119047116 0.70 ENSMUST00000152380.1
ENSMUST00000099542.2
cancer susceptibility candidate 5
chr3_+_54755574 0.70 ENSMUST00000029371.2
SMAD family member 9
chr2_-_127521358 0.70 ENSMUST00000028850.8
ENSMUST00000103215.4
Kv channel interacting protein 3, calsenilin
chr4_+_126556994 0.69 ENSMUST00000147675.1
claspin
chr9_-_21760275 0.69 ENSMUST00000098942.4
SPC24, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chrX_+_153126897 0.68 ENSMUST00000163801.1
forkhead box R2
chrM_+_9452 0.65 ENSMUST00000082411.1
mitochondrially encoded NADH dehydrogenase 3
chr6_+_34746368 0.65 ENSMUST00000142716.1
caldesmon 1
chr4_+_150237694 0.65 ENSMUST00000141931.1
enolase 1, alpha non-neuron
chr16_-_93929512 0.65 ENSMUST00000177648.1
claudin 14
chr17_-_35838208 0.64 ENSMUST00000134978.2
tubulin, beta 5 class I
chrX_+_56787701 0.64 ENSMUST00000151033.1
four and a half LIM domains 1
chr11_+_58171648 0.64 ENSMUST00000020820.1
mitochondrial ribosomal protein L22
chr17_+_27839974 0.64 ENSMUST00000071006.7
U1 small nuclear ribonucleoprotein C
chr9_-_53248106 0.62 ENSMUST00000065630.6
DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
chr11_-_121388186 0.62 ENSMUST00000106107.2
Rab40b, member RAS oncogene family
chrX_+_153139941 0.61 ENSMUST00000039720.4
ENSMUST00000144175.2
Ras-related GTP binding B
chr2_-_71055534 0.61 ENSMUST00000090849.5
ENSMUST00000100037.2
ENSMUST00000112186.2
methyltransferase like 8
chr2_+_11705355 0.60 ENSMUST00000128156.2
interleukin 15 receptor, alpha chain
chr14_+_116925379 0.60 ENSMUST00000088483.3
glypican 6
chr1_+_161070767 0.60 ENSMUST00000111618.1
ENSMUST00000111620.3
ENSMUST00000028035.7
centromere protein L
chr6_-_67376147 0.58 ENSMUST00000018485.3
interleukin 12 receptor, beta 2
chrM_+_7759 0.56 ENSMUST00000082407.1
ENSMUST00000082408.1
mitochondrially encoded ATP synthase 8
mitochondrially encoded ATP synthase 6
chr1_-_38821215 0.56 ENSMUST00000039612.4
LON peptidase N-terminal domain and ring finger 2
chr17_+_8182247 0.56 ENSMUST00000161898.1
Fgfr1 oncogene partner
chr4_-_119658781 0.54 ENSMUST00000106309.2
ENSMUST00000044426.7
guanylate cyclase activator 2b (retina)
chr2_-_5676046 0.53 ENSMUST00000114987.3
calcium/calmodulin-dependent protein kinase ID
chr9_-_20959785 0.53 ENSMUST00000177754.1
DNA methyltransferase (cytosine-5) 1
chr8_-_116921365 0.52 ENSMUST00000128304.1
COX assembly mitochondrial protein 2
chr18_-_34720269 0.52 ENSMUST00000025224.7
glial cell line derived neurotrophic factor family receptor alpha 3
chr12_-_87444017 0.51 ENSMUST00000091090.4
RIKEN cDNA 2700073G19 gene
chr6_+_8948608 0.51 ENSMUST00000160300.1
neurexophilin 1
chrX_+_93675088 0.50 ENSMUST00000045898.3
phosphate cytidylyltransferase 1, choline, beta isoform
chr14_+_32321987 0.50 ENSMUST00000022480.7
oxoglutarate dehydrogenase-like
chr17_-_35838259 0.49 ENSMUST00000001566.8
tubulin, beta 5 class I
chr3_-_129831374 0.48 ENSMUST00000029643.8
GAR1 ribonucleoprotein homolog (yeast)
chr12_+_38780284 0.48 ENSMUST00000162563.1
ENSMUST00000161164.1
ENSMUST00000160996.1
ets variant gene 1
chr9_+_57998036 0.48 ENSMUST00000181289.1
predicted gene, 17322
chr9_+_32224246 0.48 ENSMUST00000168954.2
Rho GTPase activating protein 32
chr7_-_30559600 0.48 ENSMUST00000043975.4
ENSMUST00000156241.1
lin-37 homolog (C. elegans)
chr8_+_84689308 0.47 ENSMUST00000125370.3
ENSMUST00000175784.1
tRNA methyltransferase 1
chr12_-_110696248 0.47 ENSMUST00000124156.1
heat shock protein 90, alpha (cytosolic), class A member 1
chr3_-_94436574 0.47 ENSMUST00000029787.4
ornithine decarboxylase antizyme 3
chr11_-_97782409 0.47 ENSMUST00000103146.4
ribosomal protein L23
chr2_-_73453918 0.47 ENSMUST00000102679.1
WAS/WASL interacting protein family, member 1
chr7_-_62464505 0.47 ENSMUST00000094339.2
paternally expressed 12
chr7_+_16781341 0.47 ENSMUST00000108496.2
solute carrier family 1 (neutral amino acid transporter), member 5
chr14_+_24490678 0.46 ENSMUST00000169826.1
ENSMUST00000112384.3
ribosomal protein S24
chr2_-_80128834 0.45 ENSMUST00000102654.4
ENSMUST00000102655.3
phosphodiesterase 1A, calmodulin-dependent
chr18_-_43687695 0.45 ENSMUST00000082254.6
janus kinase and microtubule interacting protein 2
chr3_-_88410295 0.45 ENSMUST00000056370.7
polyamine-modulated factor 1
chr16_+_94425083 0.45 ENSMUST00000141176.1
tetratricopeptide repeat domain 3
chr8_-_122915987 0.44 ENSMUST00000098333.4
ankyrin repeat domain 11
chr14_-_47276790 0.44 ENSMUST00000111792.1
ENSMUST00000111791.1
ENSMUST00000111790.1
WD repeat and HMG-box DNA binding protein 1
chr2_-_150255591 0.44 ENSMUST00000063463.5
predicted gene 21994
chr19_+_23723279 0.44 ENSMUST00000067077.1
predicted gene 9938
chrX_+_134585644 0.44 ENSMUST00000113211.1
ribosomal protein L36A
chr5_-_148371525 0.44 ENSMUST00000138596.1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr5_-_20882072 0.44 ENSMUST00000118174.1
putative homeodomain transcription factor 2
chr8_-_116921408 0.44 ENSMUST00000078589.6
ENSMUST00000148235.1
COX assembly mitochondrial protein 2
chr5_-_138170992 0.43 ENSMUST00000139983.1
minichromosome maintenance deficient 7 (S. cerevisiae)
chr5_-_138171248 0.43 ENSMUST00000153867.1
minichromosome maintenance deficient 7 (S. cerevisiae)
chr19_-_29523159 0.43 ENSMUST00000180986.1
RIKEN cDNA A930007I19 gene
chr7_+_16875302 0.43 ENSMUST00000108493.1
dapper homolog 3, antagonist of beta-catenin (xenopus)
chr5_+_90768511 0.42 ENSMUST00000031319.6
pro-platelet basic protein
chr10_+_62449489 0.42 ENSMUST00000181110.1
RIKEN cDNA 4930507D05 gene
chr12_+_38780817 0.42 ENSMUST00000160856.1
ets variant gene 1
chr17_-_42692244 0.42 ENSMUST00000170723.1
ENSMUST00000164524.1
ENSMUST00000024711.4
ENSMUST00000167993.1
G protein-coupled receptor 115
chr11_+_68691906 0.42 ENSMUST00000102611.3
myosin, heavy polypeptide 10, non-muscle
chr15_+_25940846 0.41 ENSMUST00000110438.1
family with sequence similarity 134, member B
chr8_+_84990585 0.41 ENSMUST00000064495.6
hook homolog 2 (Drosophila)
chr1_-_93342734 0.41 ENSMUST00000027493.3
PAS domain containing serine/threonine kinase
chr2_-_29787622 0.41 ENSMUST00000177467.1
ENSMUST00000113807.3
TruB pseudouridine (psi) synthase homolog 2 (E. coli)
chrX_+_159303266 0.39 ENSMUST00000112491.1
ribosomal protein S6 kinase polypeptide 3
chr19_-_40588374 0.39 ENSMUST00000175932.1
ENSMUST00000176955.1
ENSMUST00000149476.2
aldehyde dehydrogenase 18 family, member A1
chrX_+_150547375 0.39 ENSMUST00000066337.6
ENSMUST00000112715.1
aminolevulinic acid synthase 2, erythroid
chr19_+_8735808 0.38 ENSMUST00000049424.9
WD repeat domain 74
chr7_+_89404356 0.38 ENSMUST00000058755.3
frizzled homolog 4 (Drosophila)
chr12_+_38781093 0.38 ENSMUST00000161513.1
ets variant gene 1
chr19_-_5875210 0.38 ENSMUST00000155227.1
FERM domain containing 8
chr8_+_84689247 0.38 ENSMUST00000109767.2
ENSMUST00000177084.1
ENSMUST00000109768.2
ENSMUST00000152301.2
ENSMUST00000177423.1
tRNA methyltransferase 1
chr3_-_121171678 0.38 ENSMUST00000170781.1
ENSMUST00000039761.5
ENSMUST00000106467.1
ENSMUST00000106466.3
ENSMUST00000164925.2
RWD domain containing 3
chr5_-_150518164 0.38 ENSMUST00000118769.1
zygote arrest 1-like
chr6_-_136781718 0.37 ENSMUST00000078095.6
ENSMUST00000032338.7
guanylate cyclase 2c
chrM_+_3906 0.37 ENSMUST00000082396.1
mitochondrially encoded NADH dehydrogenase 2
chr3_-_107931579 0.37 ENSMUST00000133947.2
ENSMUST00000124215.1
ENSMUST00000106688.1
ENSMUST00000106687.2
glutathione S-transferase, mu 7
chr1_-_134955908 0.36 ENSMUST00000045665.6
ENSMUST00000086444.4
ENSMUST00000112163.1
protein phosphatase 1, regulatory (inhibitor) subunit 12B
chr1_+_53061637 0.36 ENSMUST00000027269.5
myostatin
chr15_+_92344359 0.35 ENSMUST00000181901.1
predicted gene, 26760
chr1_+_40515362 0.35 ENSMUST00000027237.5
interleukin 18 receptor accessory protein
chr9_-_66514567 0.35 ENSMUST00000056890.8
F-box and leucine-rich repeat protein 22
chr5_-_112228934 0.35 ENSMUST00000181535.2
myocardial infarction associated transcript (non-protein coding)
chr2_-_180104463 0.35 ENSMUST00000056480.3
histamine receptor H3
chr11_+_76179658 0.34 ENSMUST00000129853.1
ENSMUST00000179223.1
family with sequence similarity 57, member A
family with sequence similarity 57, member A
chr13_-_110280103 0.34 ENSMUST00000167824.1
RAB3C, member RAS oncogene family
chr7_+_101378183 0.34 ENSMUST00000084895.5
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr18_+_67641589 0.34 ENSMUST00000025418.3
proteasome (prosome, macropain) assembly chaperone 2
chr5_-_84417359 0.34 ENSMUST00000113401.1
Eph receptor A5
chr9_+_27299205 0.33 ENSMUST00000115247.1
ENSMUST00000133213.1
immunoglobulin superfamily, member 9B
chr9_+_113812547 0.33 ENSMUST00000166734.2
ENSMUST00000111838.2
ENSMUST00000163895.2
CLIP associating protein 2
chr4_-_59783800 0.33 ENSMUST00000107526.1
ENSMUST00000095063.4
INTS3 and NABP interacting protein
chr11_+_116843278 0.32 ENSMUST00000106370.3
methyltransferase like 23
chr5_-_138171216 0.32 ENSMUST00000147920.1
minichromosome maintenance deficient 7 (S. cerevisiae)
chr3_-_33844255 0.32 ENSMUST00000029222.5
coiled-coil domain containing 39
chr14_-_18893376 0.32 ENSMUST00000151926.1
ubiquitin-conjugating enzyme E2E 2
chr5_-_87092546 0.32 ENSMUST00000132667.1
ENSMUST00000145617.1
ENSMUST00000094649.4
UDP glucuronosyltransferase 2 family, polypeptide B36
chr13_-_34963788 0.32 ENSMUST00000164155.1
ENSMUST00000021853.5
enoyl-Coenzyme A delta isomerase 3
chr8_+_45628176 0.32 ENSMUST00000130850.1
sorbin and SH3 domain containing 2
chr16_-_75909272 0.31 ENSMUST00000114239.2
SAM domain, SH3 domain and nuclear localization signals, 1
chr1_-_173367638 0.31 ENSMUST00000005470.4
ENSMUST00000111220.1
cell adhesion molecule 3
chr3_+_79884496 0.31 ENSMUST00000118853.1
family with sequence similarity 198, member B
chr11_-_6626030 0.31 ENSMUST00000000394.7
ENSMUST00000136682.1
transforming growth factor beta regulated gene 4
chr17_+_46496753 0.31 ENSMUST00000046497.6
2'-deoxynucleoside 5'-phosphate N-hydrolase 1
chr4_+_8690399 0.30 ENSMUST00000127476.1
chromodomain helicase DNA binding protein 7
chr7_-_24724237 0.30 ENSMUST00000081657.4
predicted gene 4763
chr12_-_101028983 0.30 ENSMUST00000068411.3
ENSMUST00000085096.3
coiled-coil domain containing 88C
chr12_-_81568474 0.30 ENSMUST00000008582.3
a disintegrin and metallopeptidase domain 21
chr7_-_5413145 0.30 ENSMUST00000108569.2
vomeronasal 1 receptor 58
chr1_-_161070613 0.30 ENSMUST00000035430.3
aspartyl-tRNA synthetase 2 (mitochondrial)
chr9_-_55919605 0.30 ENSMUST00000037408.8
S phase cyclin A-associated protein in the ER
chr5_+_139543889 0.30 ENSMUST00000174792.1
ENSMUST00000031523.8
UNC homeobox
chr13_+_4574075 0.29 ENSMUST00000021628.3
aldo-keto reductase family 1, member C21
chr6_-_124863877 0.29 ENSMUST00000046893.7
G protein-coupled receptor 162
chr15_-_98195542 0.29 ENSMUST00000165379.1
ENSMUST00000142443.1
olfactory receptor 288
chr19_+_55180799 0.29 ENSMUST00000025936.5
tectorin beta
chr7_+_126776939 0.29 ENSMUST00000038614.5
ENSMUST00000170882.1
ENSMUST00000106359.1
ENSMUST00000106357.1
ENSMUST00000145762.1
ENSMUST00000132643.1
ENSMUST00000106356.1
yippee-like 3 (Drosophila)
chr15_+_102073773 0.28 ENSMUST00000169681.1
eukaryotic translation initiation factor 4B
chr3_+_37639945 0.28 ENSMUST00000108109.1
ENSMUST00000038569.1
sprouty homolog 1 (Drosophila)
chr3_+_115888139 0.28 ENSMUST00000106505.1
ENSMUST00000043342.9
DPH5 homolog (S. cerevisiae)
chr7_-_102099932 0.28 ENSMUST00000106934.1
ADP-ribosyltransferase 5
chr17_-_35909626 0.28 ENSMUST00000141132.1
alpha tubulin acetyltransferase 1
chr5_+_108461222 0.28 ENSMUST00000046975.5
ENSMUST00000112597.1
polycomb group ring finger 3
chr18_-_56572888 0.28 ENSMUST00000174518.1
aldehyde dehydrogenase family 7, member A1
chr19_-_56548013 0.28 ENSMUST00000182059.1
DNA cross-link repair 1A, PSO2 homolog (S. cerevisiae)
chr3_+_55782500 0.28 ENSMUST00000075422.4
mab-21-like 1 (C. elegans)
chr2_-_45110336 0.28 ENSMUST00000028229.6
ENSMUST00000152232.1
zinc finger E-box binding homeobox 2
chr9_+_74953053 0.28 ENSMUST00000170846.1
family with sequence similarity 214, member A
chr13_-_24761440 0.28 ENSMUST00000176890.1
ENSMUST00000175689.1
geminin
chr7_+_103550368 0.27 ENSMUST00000106888.1
olfactory receptor 613
chr19_-_41933276 0.27 ENSMUST00000075280.4
ENSMUST00000112123.2
exosome component 1
chr9_+_75051977 0.27 ENSMUST00000170310.1
ENSMUST00000166549.1
cAMP-regulated phosphoprotein 19
chr5_-_145201829 0.27 ENSMUST00000162220.1
ENSMUST00000031632.8
zinc finger with KRAB and SCAN domains 14
chr6_+_41951625 0.27 ENSMUST00000031898.4
seminal vesicle antigen-like 1
chr4_+_95557494 0.27 ENSMUST00000079223.4
ENSMUST00000177394.1
FGGY carbohydrate kinase domain containing
chr7_+_17087934 0.27 ENSMUST00000152671.1
pregnancy specific glycoprotein 16
chr5_-_62766153 0.26 ENSMUST00000076623.4
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr11_-_76217490 0.26 ENSMUST00000102500.4
gem (nuclear organelle) associated protein 4

Network of associatons between targets according to the STRING database.

First level regulatory network of Dlx5_Dlx4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0015881 creatine transport(GO:0015881)
0.4 1.2 GO:1904868 telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
0.3 1.7 GO:0060023 soft palate development(GO:0060023)
0.3 0.9 GO:0002940 tRNA N2-guanine methylation(GO:0002940)
0.2 1.2 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.2 1.0 GO:0045726 positive regulation of integrin biosynthetic process(GO:0045726)
0.2 4.0 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.2 1.0 GO:0051661 maintenance of centrosome location(GO:0051661)
0.2 0.5 GO:0006592 ornithine biosynthetic process(GO:0006592)
0.2 1.0 GO:0045583 regulation of cytotoxic T cell differentiation(GO:0045583) positive regulation of cytotoxic T cell differentiation(GO:0045585)
0.2 0.5 GO:1902071 regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
0.1 1.6 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.1 0.4 GO:0070650 actin filament bundle distribution(GO:0070650)
0.1 1.0 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.1 0.7 GO:0072717 cellular response to actinomycin D(GO:0072717)
0.1 0.5 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.1 0.9 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.1 0.4 GO:0061300 cerebellum vasculature development(GO:0061300)
0.1 1.2 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 0.5 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.1 0.5 GO:0015825 L-serine transport(GO:0015825)
0.1 1.0 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.1 1.0 GO:0033227 dsRNA transport(GO:0033227)
0.1 0.4 GO:0070829 heterochromatin maintenance(GO:0070829)
0.1 1.5 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.1 1.0 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.1 0.7 GO:0001880 Mullerian duct regression(GO:0001880)
0.1 0.5 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.1 0.3 GO:0071929 alpha-tubulin acetylation(GO:0071929)
0.1 1.2 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.1 0.4 GO:0014732 skeletal muscle atrophy(GO:0014732)
0.1 0.7 GO:0035404 histone-serine phosphorylation(GO:0035404)
0.1 0.2 GO:0070827 chromatin maintenance(GO:0070827)
0.1 0.7 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.1 0.4 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.1 0.2 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.1 0.3 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 0.2 GO:2000537 signal complex assembly(GO:0007172) regulation of cGMP-mediated signaling(GO:0010752) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.1 0.2 GO:1904760 myofibroblast differentiation(GO:0036446) regulation of myofibroblast differentiation(GO:1904760)
0.1 0.6 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.1 0.2 GO:0006295 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720) nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295) nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296) positive regulation of t-circle formation(GO:1904431)
0.1 0.3 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.1 0.3 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.1 0.1 GO:2000698 positive regulation of epithelial cell differentiation involved in kidney development(GO:2000698)
0.1 0.9 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.1 0.3 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.1 0.2 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.1 0.3 GO:0048022 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.1 0.2 GO:0010749 regulation of nitric oxide mediated signal transduction(GO:0010749)
0.1 0.8 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 0.2 GO:0019046 release from viral latency(GO:0019046) regulation of DNA strand elongation(GO:0060382)
0.1 0.6 GO:0080009 mRNA methylation(GO:0080009)
0.1 0.1 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.1 0.2 GO:0032685 negative regulation of granulocyte macrophage colony-stimulating factor production(GO:0032685)
0.1 0.5 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.1 0.5 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.1 0.3 GO:0014063 negative regulation of serotonin secretion(GO:0014063)
0.1 0.3 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.1 0.3 GO:0014022 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.1 0.1 GO:1900239 regulation of phenotypic switching(GO:1900239) regulation of cardiac vascular smooth muscle cell differentiation(GO:2000722) positive regulation of cardiac vascular smooth muscle cell differentiation(GO:2000724)
0.1 0.2 GO:1902174 positive regulation of keratinocyte apoptotic process(GO:1902174)
0.1 0.8 GO:0042118 endothelial cell activation(GO:0042118)
0.1 0.3 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.1 0.3 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.1 0.4 GO:0051410 detoxification of nitrogen compound(GO:0051410) cellular detoxification of nitrogen compound(GO:0070458) cellular response to caffeine(GO:0071313)
0.1 0.4 GO:0030035 microspike assembly(GO:0030035)
0.1 1.6 GO:0010842 retina layer formation(GO:0010842)
0.1 0.3 GO:0033762 response to glucagon(GO:0033762)
0.0 0.2 GO:2001168 regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.0 0.1 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0 0.3 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.0 0.1 GO:0006404 RNA import into nucleus(GO:0006404) snRNA transport(GO:0051030)
0.0 0.1 GO:1903632 positive regulation of aminoacyl-tRNA ligase activity(GO:1903632) regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.0 0.3 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.0 1.4 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.0 0.3 GO:0048840 otolith development(GO:0048840)
0.0 0.3 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.0 0.1 GO:1903659 transforming growth factor beta activation(GO:0036363) regulation of complement-dependent cytotoxicity(GO:1903659) negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.0 0.2 GO:0010920 negative regulation of inositol phosphate biosynthetic process(GO:0010920) protein secretion by platelet(GO:0070560)
0.0 0.3 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.6 GO:0035881 amacrine cell differentiation(GO:0035881)
0.0 0.2 GO:2000360 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032) negative regulation of binding of sperm to zona pellucida(GO:2000360)
0.0 0.4 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719)
0.0 0.1 GO:0060221 retinal rod cell differentiation(GO:0060221)
0.0 0.3 GO:0009162 deoxyribonucleoside monophosphate metabolic process(GO:0009162)
0.0 0.2 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.1 GO:0031443 fast-twitch skeletal muscle fiber contraction(GO:0031443)
0.0 1.6 GO:0006182 cGMP biosynthetic process(GO:0006182)
0.0 0.2 GO:0090214 spongiotrophoblast layer developmental growth(GO:0090214)
0.0 0.2 GO:0034628 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.0 0.4 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 0.2 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.0 0.3 GO:0006265 DNA topological change(GO:0006265)
0.0 0.2 GO:2001012 mesenchymal cell differentiation involved in kidney development(GO:0072161) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.0 1.0 GO:0034508 centromere complex assembly(GO:0034508)
0.0 1.0 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.2 GO:0070197 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0 0.2 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.0 0.3 GO:1904871 protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) protein localization to nucleoplasm(GO:1990173)
0.0 0.7 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.0 0.1 GO:1902219 negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
0.0 0.6 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.1 GO:0060912 cardiac cell fate specification(GO:0060912)
0.0 0.3 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.0 0.4 GO:0015809 arginine transport(GO:0015809)
0.0 0.2 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.5 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.2 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.0 0.4 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.0 0.6 GO:0034453 microtubule anchoring(GO:0034453)
0.0 0.3 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.3 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 0.1 GO:0035633 maintenance of blood-brain barrier(GO:0035633)
0.0 0.1 GO:0051790 short-chain fatty acid biosynthetic process(GO:0051790)
0.0 0.1 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.0 0.4 GO:0001522 pseudouridine synthesis(GO:0001522)
0.0 0.7 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.4 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 0.8 GO:0001773 myeloid dendritic cell activation(GO:0001773)
0.0 0.0 GO:0034442 regulation of lipoprotein oxidation(GO:0034442) negative regulation of lipoprotein oxidation(GO:0034443)
0.0 0.5 GO:0032825 positive regulation of natural killer cell differentiation(GO:0032825)
0.0 0.2 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.8 GO:0048266 behavioral response to pain(GO:0048266)
0.0 0.2 GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.0 0.3 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.1 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.1 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0 1.9 GO:0008543 fibroblast growth factor receptor signaling pathway(GO:0008543)
0.0 0.2 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.0 0.7 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 0.1 GO:1903232 melanosome assembly(GO:1903232)
0.0 0.2 GO:2000653 regulation of genetic imprinting(GO:2000653)
0.0 1.0 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 0.1 GO:1904253 positive regulation of bile acid biosynthetic process(GO:0070859) positive regulation of bile acid metabolic process(GO:1904253)
0.0 0.3 GO:0021889 olfactory bulb interneuron differentiation(GO:0021889)
0.0 0.1 GO:2000402 negative regulation of lymphocyte migration(GO:2000402)
0.0 0.1 GO:0090365 regulation of mRNA modification(GO:0090365)
0.0 0.7 GO:0071385 cellular response to corticosteroid stimulus(GO:0071384) cellular response to glucocorticoid stimulus(GO:0071385)
0.0 0.3 GO:0019321 pentose metabolic process(GO:0019321)
0.0 0.5 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.1 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.0 0.2 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.1 GO:0002194 hepatocyte cell migration(GO:0002194) optic placode formation involved in camera-type eye formation(GO:0046619) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.0 0.2 GO:0042178 xenobiotic catabolic process(GO:0042178)
0.0 0.1 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.0 0.1 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.0 0.1 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.0 0.1 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.0 0.3 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 0.0 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.0 0.2 GO:0035095 behavioral response to nicotine(GO:0035095)
0.0 0.1 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.0 0.0 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 0.2 GO:0090266 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.0 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.0 0.1 GO:0060709 glycogen cell differentiation involved in embryonic placenta development(GO:0060709)
0.0 0.2 GO:0048485 sympathetic nervous system development(GO:0048485)
0.0 0.1 GO:0032328 alanine transport(GO:0032328)
0.0 0.2 GO:0007635 chemosensory behavior(GO:0007635)
0.0 0.3 GO:0045652 regulation of megakaryocyte differentiation(GO:0045652)
0.0 0.6 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 0.1 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.6 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.0 0.1 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.1 GO:0098953 receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628) protein localization to postsynaptic specialization membrane(GO:0099633) neurotransmitter receptor localization to postsynaptic specialization membrane(GO:0099645)
0.0 0.4 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.1 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.1 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.2 GO:0032570 response to progesterone(GO:0032570)
0.0 0.2 GO:0050687 negative regulation of defense response to virus(GO:0050687)
0.0 0.1 GO:0002121 inter-male aggressive behavior(GO:0002121)
0.0 0.0 GO:0006566 threonine metabolic process(GO:0006566)
0.0 0.5 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.2 GO:0032060 bleb assembly(GO:0032060)
0.0 0.8 GO:0051225 spindle assembly(GO:0051225)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0098833 presynaptic endosome(GO:0098830) presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835)
0.3 1.3 GO:0036449 microtubule minus-end(GO:0036449)
0.2 0.9 GO:0008623 CHRAC(GO:0008623)
0.2 1.0 GO:0097226 sperm mitochondrial sheath(GO:0097226)
0.1 1.0 GO:0071438 invadopodium membrane(GO:0071438)
0.1 4.3 GO:1990752 microtubule plus-end(GO:0035371) microtubule end(GO:1990752)
0.1 0.7 GO:0031262 Ndc80 complex(GO:0031262)
0.1 1.1 GO:0045298 tubulin complex(GO:0045298)
0.1 1.1 GO:0000138 Golgi trans cisterna(GO:0000138)
0.1 0.7 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.1 0.4 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 0.5 GO:0001651 dense fibrillar component(GO:0001651)
0.1 1.2 GO:0042555 MCM complex(GO:0042555)
0.1 0.2 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.1 0.4 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.1 0.7 GO:0030478 actin cap(GO:0030478)
0.1 0.4 GO:0097513 myosin II filament(GO:0097513)
0.1 0.3 GO:0070876 SOSS complex(GO:0070876)
0.1 0.6 GO:0000243 commitment complex(GO:0000243)
0.1 0.6 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 0.2 GO:0033503 HULC complex(GO:0033503)
0.1 0.3 GO:0097524 sperm plasma membrane(GO:0097524)
0.1 0.7 GO:0032797 SMN complex(GO:0032797)
0.1 0.5 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.1 1.1 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 0.2 GO:0030312 external encapsulating structure(GO:0030312)
0.1 0.2 GO:0070557 PCNA-p21 complex(GO:0070557)
0.0 0.2 GO:0042583 chromaffin granule(GO:0042583)
0.0 0.7 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 1.2 GO:0001741 XY body(GO:0001741)
0.0 2.3 GO:0043034 costamere(GO:0043034)
0.0 0.0 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.0 0.2 GO:0030891 VCB complex(GO:0030891)
0.0 1.1 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 1.6 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.7 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.1 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0 0.1 GO:0060187 cell pole(GO:0060187)
0.0 0.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.1 GO:1990032 parallel fiber(GO:1990032)
0.0 0.3 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.2 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 1.5 GO:0031672 A band(GO:0031672)
0.0 0.2 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.1 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.0 0.2 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.2 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.0 0.0 GO:0044301 climbing fiber(GO:0044301)
0.0 2.1 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.2 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0 1.4 GO:0005657 replication fork(GO:0005657)
0.0 0.2 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.0 0.3 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.2 GO:0005687 U4 snRNP(GO:0005687)
0.0 0.3 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 1.8 GO:0005581 collagen trimer(GO:0005581)
0.0 0.1 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467) 3M complex(GO:1990393)
0.0 0.1 GO:0034709 methylosome(GO:0034709)
0.0 0.2 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.1 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 0.3 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 3.0 GO:0000775 chromosome, centromeric region(GO:0000775)
0.0 1.0 GO:0005871 kinesin complex(GO:0005871)
0.0 0.2 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.3 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.0 GO:0034271 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 0.1 GO:0005688 U6 snRNP(GO:0005688)
0.0 0.7 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.2 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.5 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.1 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.4 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.1 GO:0042382 paraspeckles(GO:0042382)
0.0 0.1 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.2 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.6 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 1.7 GO:0001650 fibrillar center(GO:0001650)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0005308 creatine transmembrane transporter activity(GO:0005308)
0.3 1.0 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.3 1.6 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.3 1.5 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.2 1.1 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.2 0.8 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.2 1.2 GO:0032407 MutLalpha complex binding(GO:0032405) MutSalpha complex binding(GO:0032407)
0.2 1.0 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.2 1.1 GO:0002135 CTP binding(GO:0002135)
0.2 0.5 GO:0004349 glutamate 5-kinase activity(GO:0004349) glutamate-5-semialdehyde dehydrogenase activity(GO:0004350) delta1-pyrroline-5-carboxylate synthetase activity(GO:0017084) amino acid kinase activity(GO:0019202)
0.2 0.9 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.2 1.0 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.2 1.5 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.2 0.9 GO:0001595 angiotensin receptor activity(GO:0001595)
0.1 0.4 GO:0016748 succinyltransferase activity(GO:0016748)
0.1 0.5 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.1 0.6 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.1 0.5 GO:0010853 cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.1 2.2 GO:0042288 MHC class I protein binding(GO:0042288)
0.1 0.5 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 0.3 GO:1902121 androsterone dehydrogenase activity(GO:0047023) NADP+ binding(GO:0070401) lithocholic acid binding(GO:1902121)
0.1 0.8 GO:1990446 U1 snRNP binding(GO:1990446)
0.1 0.8 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.1 0.3 GO:0019150 D-ribulokinase activity(GO:0019150)
0.1 0.2 GO:0001729 ceramide kinase activity(GO:0001729)
0.1 0.7 GO:0035174 histone serine kinase activity(GO:0035174)
0.1 0.9 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.1 0.7 GO:0001727 lipid kinase activity(GO:0001727)
0.1 0.5 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.1 0.3 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.1 0.3 GO:0008802 betaine-aldehyde dehydrogenase activity(GO:0008802)
0.1 0.5 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.1 0.2 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.1 0.5 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 0.3 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.1 0.5 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 0.2 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.1 0.3 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.1 0.6 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 0.2 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.1 0.7 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.1 3.0 GO:0042169 SH2 domain binding(GO:0042169)
0.1 0.4 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.1 0.1 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.1 0.3 GO:0042296 ISG15 transferase activity(GO:0042296)
0.1 0.5 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 0.2 GO:0071207 histone pre-mRNA stem-loop binding(GO:0071207)
0.1 0.2 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.1 0.5 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.1 0.2 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.1 0.2 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.1 0.3 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.2 GO:0043758 acetate-CoA ligase (ADP-forming) activity(GO:0043758)
0.0 0.3 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.0 2.4 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.5 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.0 0.2 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.0 0.4 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.1 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.0 0.1 GO:0042610 CD8 receptor binding(GO:0042610)
0.0 1.1 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.3 GO:0033592 RNA strand annealing activity(GO:0033592)
0.0 0.2 GO:0070728 leucine binding(GO:0070728)
0.0 0.3 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.2 GO:0004568 chitinase activity(GO:0004568)
0.0 0.2 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.5 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.2 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.0 0.3 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.1 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.0 0.1 GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315)
0.0 0.2 GO:0004515 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0 1.0 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 1.3 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.2 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.0 0.4 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.2 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.2 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 0.5 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.1 GO:0031493 nucleosomal histone binding(GO:0031493)
0.0 0.2 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.4 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.3 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.2 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.2 GO:0003909 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 0.3 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.9 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.2 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.4 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.3 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.2 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.6 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.1 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.8 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.1 GO:0045159 myosin II binding(GO:0045159)
0.0 0.1 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.0 0.1 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 0.4 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 1.0 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.1 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.0 0.0 GO:0004356 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211)
0.0 0.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.2 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 1.0 GO:0003777 microtubule motor activity(GO:0003777)
0.0 2.9 GO:0051015 actin filament binding(GO:0051015)
0.0 0.5 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.3 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.0 GO:0004771 sterol esterase activity(GO:0004771)
0.0 0.1 GO:0034235 GPI anchor binding(GO:0034235)
0.0 0.2 GO:0003678 DNA helicase activity(GO:0003678)
0.0 0.2 GO:0042166 acetylcholine-gated cation channel activity(GO:0022848) acetylcholine binding(GO:0042166)
0.0 1.0 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.2 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.0 0.5 GO:0031369 translation initiation factor binding(GO:0031369)
0.0 0.1 GO:1990405 protein antigen binding(GO:1990405)
0.0 0.0 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.1 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.5 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.2 GO:0070402 NADPH binding(GO:0070402)
0.0 0.1 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.0 0.1 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.5 GO:0070063 RNA polymerase binding(GO:0070063)
0.0 0.1 GO:0015924 mannosyl-oligosaccharide mannosidase activity(GO:0015924)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 4.0 PID ATR PATHWAY ATR signaling pathway
0.1 0.3 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.1 0.7 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.9 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 1.3 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 3.7 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 1.6 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.4 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.2 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 1.1 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.6 PID IL27 PATHWAY IL27-mediated signaling events
0.0 1.3 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.3 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.5 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.7 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.4 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.3 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.4 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.7 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 1.0 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.7 PID P53 REGULATION PATHWAY p53 pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.2 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.1 0.9 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.1 1.5 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 1.2 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.1 1.0 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 4.7 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 1.4 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.2 REACTOME ORC1 REMOVAL FROM CHROMATIN Genes involved in Orc1 removal from chromatin
0.0 0.8 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.3 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 0.9 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.6 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.2 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.6 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.2 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.8 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.9 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 1.4 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.4 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.2 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.3 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.7 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.8 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.3 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 1.7 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.4 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.6 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.5 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.3 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 0.4 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.7 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.2 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.2 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.5 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.9 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK