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12D miR HR13_24

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Results for Irx6_Irx2_Irx3

Z-value: 0.59

Motif logo

Transcription factors associated with Irx6_Irx2_Irx3

Gene Symbol Gene ID Gene Info
ENSMUSG00000031738.8 Iroquois homeobox 6
ENSMUSG00000001504.9 Iroquois homeobox 2
ENSMUSG00000031734.11 Iroquois related homeobox 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Irx2mm10_v2_chr13_+_72628802_726288250.721.3e-02Click!
Irx3mm10_v2_chr8_-_91801948_918020670.097.8e-01Click!

Activity profile of Irx6_Irx2_Irx3 motif

Sorted Z-values of Irx6_Irx2_Irx3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr16_-_45492962 0.68 ENSMUST00000114585.2
predicted gene 609
chr2_+_24345305 0.58 ENSMUST00000114482.1
interleukin 1 receptor antagonist
chr7_-_24333959 0.52 ENSMUST00000069562.4
tescalcin-like
chr5_-_117389029 0.45 ENSMUST00000111953.1
ENSMUST00000086461.6
replication factor C (activator 1) 5
chr8_+_84872105 0.45 ENSMUST00000136026.1
ENSMUST00000170296.1
synaptonemal complex central element protein 2
chr12_-_81421910 0.43 ENSMUST00000085319.3
a disintegrin and metallopeptidase domain 4
chr1_+_152750527 0.43 ENSMUST00000068875.4
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative)
chr17_-_27133902 0.40 ENSMUST00000119227.1
ENSMUST00000025045.8
ubiquinol-cytochrome c reductase complex assembly factor 2
chr7_-_112159034 0.39 ENSMUST00000033036.5
dickkopf homolog 3 (Xenopus laevis)
chr16_+_32756336 0.37 ENSMUST00000135753.1
mucin 4
chr5_-_6876523 0.34 ENSMUST00000164784.1
zinc finger protein 804B
chr14_+_24622132 0.34 ENSMUST00000159744.1
RIKEN cDNA 4930428N03 gene
chr8_-_25091341 0.34 ENSMUST00000125466.1
pleckstrin homology domain-containing, family A (phosphoinositide binding specific) member 2
chr6_-_113719880 0.33 ENSMUST00000064993.5
ghrelin
chr7_+_12897800 0.33 ENSMUST00000055528.4
ENSMUST00000117189.1
ENSMUST00000120809.1
ENSMUST00000119989.1
zinc finger and SCAN domain containing 22
chr5_-_120887582 0.32 ENSMUST00000086368.5
2'-5' oligoadenylate synthetase 1G
chrX_-_161832112 0.32 ENSMUST00000129329.1
predicted gene 15205
chr4_-_108118504 0.30 ENSMUST00000149106.1
sterol carrier protein 2, liver
chr11_-_76399107 0.30 ENSMUST00000021204.3
nucleoredoxin
chr8_+_13037308 0.30 ENSMUST00000063820.5
ENSMUST00000033821.4
coagulation factor X
chr2_+_24345282 0.29 ENSMUST00000114485.2
interleukin 1 receptor antagonist
chr13_+_76579670 0.29 ENSMUST00000126960.1
ENSMUST00000109583.2
multiple C2 domains, transmembrane 1
chr3_+_40540751 0.28 ENSMUST00000091186.3
inturned planar cell polarity effector homolog (Drosophila)
chr3_+_106113229 0.28 ENSMUST00000079132.5
ENSMUST00000139086.1
chitinase, acidic
chr12_+_52516077 0.28 ENSMUST00000110725.1
Rho GTPase activating protein 5
chr8_+_84908560 0.25 ENSMUST00000003910.6
ENSMUST00000109744.1
deoxyribonuclease II alpha
chr1_+_60181495 0.23 ENSMUST00000160834.1
neurobeachin like 1
chr11_-_26591729 0.23 ENSMUST00000109504.1
vaccinia related kinase 2
chr10_-_125328957 0.23 ENSMUST00000063318.2
solute carrier family 16 (monocarboxylic acid transporters), member 7
chr16_-_17838173 0.22 ENSMUST00000118960.1
carbonic anhydrase 15
chr6_-_56901870 0.22 ENSMUST00000101367.2
5'-nucleotidase, cytosolic III
chr17_+_35506018 0.21 ENSMUST00000025271.10
POU domain, class 5, transcription factor 1
chr13_-_21556020 0.20 ENSMUST00000068163.1
olfactory receptor 1535
chr1_+_191036812 0.20 ENSMUST00000077889.6
RIKEN cDNA 1700022P22 gene
chr8_+_27023793 0.19 ENSMUST00000033873.7
ER lipid raft associated 2
chr3_+_121291725 0.19 ENSMUST00000039442.7
asparagine-linked glycosylation 14
chr15_-_77022632 0.19 ENSMUST00000019037.8
ENSMUST00000169226.1
myoglobin
chr9_+_106514572 0.19 ENSMUST00000085113.3
IQ motif containing F5
chr18_-_20059478 0.18 ENSMUST00000075214.2
ENSMUST00000039247.4
desmocollin 2
chr14_+_44102654 0.18 ENSMUST00000074839.6
eosinophil-associated, ribonuclease A family, member 2
chr3_+_92352141 0.18 ENSMUST00000068399.1
small proline-rich protein 2E
chr6_-_83317589 0.17 ENSMUST00000005810.6
methylenetetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofolate cyclohydrolase
chr7_+_44188205 0.17 ENSMUST00000073713.6
kallikrein 1-related peptidase b24
chr8_-_24725762 0.17 ENSMUST00000171438.1
ENSMUST00000171611.1
ENSMUST00000033958.7
a disintegrin and metallopeptidase domain 3 (cyritestin)
chr1_+_10039762 0.17 ENSMUST00000122156.1
ENSMUST00000118263.1
ENSMUST00000119714.1
centrosome and spindle pole associated protein 1
chr3_-_57651667 0.17 ENSMUST00000160959.1
COMM domain containing 2
chr14_+_31001414 0.17 ENSMUST00000022476.7
glycosyltransferase 8 domain containing 1
chr13_+_4574075 0.17 ENSMUST00000021628.3
aldo-keto reductase family 1, member C21
chr17_-_37280418 0.17 ENSMUST00000077585.2
olfactory receptor 99
chr8_+_84908680 0.16 ENSMUST00000145292.1
deoxyribonuclease II alpha
chr6_+_80019008 0.16 ENSMUST00000126399.1
ENSMUST00000136421.1
leucine rich repeat transmembrane neuronal 4
chr14_+_31001383 0.16 ENSMUST00000168584.1
glycosyltransferase 8 domain containing 1
chr18_-_37178493 0.16 ENSMUST00000181887.1
ENSMUST00000180516.1
predicted gene 10544
chr15_+_102503722 0.16 ENSMUST00000096145.4
predicted gene 10337
chr2_-_144270852 0.15 ENSMUST00000110030.3
sorting nexin 5
chr13_-_34077992 0.15 ENSMUST00000056427.8
tubulin, beta 2A class IIA
chr4_-_76344227 0.15 ENSMUST00000050757.9
protein tyrosine phosphatase, receptor type, D
chr8_-_105991741 0.15 ENSMUST00000117555.1
ENSMUST00000034373.7
dipeptidase 2
chr14_+_24622151 0.14 ENSMUST00000159562.1
RIKEN cDNA 4930428N03 gene
chr5_+_135168283 0.14 ENSMUST00000031692.5
B cell CLL/lymphoma 7B
chr4_-_108118528 0.14 ENSMUST00000030340.8
sterol carrier protein 2, liver
chr3_-_98564038 0.14 ENSMUST00000058728.5
predicted gene 10681
chrX_+_9885622 0.14 ENSMUST00000067529.2
ENSMUST00000086165.3
synaptotagmin-like 5
chr14_-_31001311 0.14 ENSMUST00000161219.1
ENSMUST00000182501.1
signal peptidase complex subunit 1 homolog (S. cerevisiae)
chr11_-_109472611 0.14 ENSMUST00000168740.1
solute carrier family 16 (monocarboxylic acid transporters), member 6
chr3_-_59262825 0.14 ENSMUST00000050360.7
purinergic receptor P2Y, G-protein coupled 12
chr5_-_116288978 0.14 ENSMUST00000050178.6
coiled-coil domain containing 60
chr11_+_100320596 0.13 ENSMUST00000152521.1
eukaryotic translation initiation factor 1
chr1_+_4857760 0.13 ENSMUST00000081551.7
transcription elongation factor A (SII) 1
chr10_+_69151427 0.13 ENSMUST00000167286.1
Rho-related BTB domain containing 1
chr1_+_88087802 0.13 ENSMUST00000113139.1
UDP glucuronosyltransferase 1 family, polypeptide A8
chr5_+_114923234 0.13 ENSMUST00000031540.4
ENSMUST00000112143.3
2'-5' oligoadenylate synthetase-like 1
chr16_+_17331371 0.13 ENSMUST00000023450.6
ENSMUST00000161034.1
serine (or cysteine) peptidase inhibitor, clade D, member 1
chr7_+_82851963 0.13 ENSMUST00000179662.1
RIKEN cDNA 1700010L04 gene
chr5_-_43981757 0.13 ENSMUST00000061299.7
fibroblast growth factor binding protein 1
chr10_-_26078987 0.13 ENSMUST00000066049.6
transmembrane protein 200A
chr6_+_58833689 0.13 ENSMUST00000041401.8
hect domain and RLD 3
chr19_+_53140430 0.13 ENSMUST00000111741.2
adducin 3 (gamma)
chr2_+_86046451 0.12 ENSMUST00000079298.2
olfactory receptor 1034
chr8_+_34154563 0.12 ENSMUST00000033933.5
transmembrane protein 66
chr2_+_25288135 0.12 ENSMUST00000028340.3
transmembrane protein 210
chr10_+_63430092 0.12 ENSMUST00000105441.1
catenin (cadherin associated protein), alpha 3
chr4_-_56865135 0.12 ENSMUST00000107612.2
ENSMUST00000045142.8
catenin (cadherin associated protein), alpha-like 1
chr7_-_125349745 0.12 ENSMUST00000061823.1
RIKEN cDNA 4933440M02 gene
chr14_+_105258673 0.12 ENSMUST00000136040.2
Nedd4 family interacting protein 2
chr6_-_129237948 0.12 ENSMUST00000181238.1
ENSMUST00000180379.1
RIKEN cDNA 2310001H17 gene
chr7_-_3502465 0.12 ENSMUST00000065703.7
T cell-interacting, activating receptor on myeloid cells 1
chr13_+_19214103 0.12 ENSMUST00000103558.1
T cell receptor gamma, constant 1
chr12_+_119443410 0.11 ENSMUST00000048880.6
metastasis associated in colon cancer 1
chr14_+_63436394 0.11 ENSMUST00000121288.1
family with sequence similarity 167, member A
chr14_+_105258573 0.11 ENSMUST00000181969.1
Nedd4 family interacting protein 2
chr4_-_44711446 0.11 ENSMUST00000014174.7
paired box gene 5
chr6_+_78380700 0.11 ENSMUST00000101272.1
regenerating islet-derived 3 alpha
chr7_-_130547358 0.11 ENSMUST00000160289.1
non-SMC element 4 homolog A (S. cerevisiae)
chr1_-_149961230 0.11 ENSMUST00000070200.8
phospholipase A2, group IVA (cytosolic, calcium-dependent)
chrX_-_164980279 0.10 ENSMUST00000112247.2
motile sperm domain containing 2
chr1_+_110099295 0.10 ENSMUST00000134301.1
cadherin 7, type 2
chr14_+_105258712 0.10 ENSMUST00000138283.1
Nedd4 family interacting protein 2
chrX_+_74309089 0.10 ENSMUST00000130581.1
guanosine diphosphate (GDP) dissociation inhibitor 1
chr14_-_108914237 0.10 ENSMUST00000100322.2
SLIT and NTRK-like family, member 1
chr8_-_111876661 0.10 ENSMUST00000034431.1
transmembrane protein 170
chrX_+_100774741 0.10 ENSMUST00000113735.2
discs, large homolog 3 (Drosophila)
chr8_-_69710724 0.10 ENSMUST00000080987.6
zinc finger protein 869
chr12_+_119945957 0.10 ENSMUST00000058644.8
transmembrane protein 196
chr3_-_121643485 0.10 ENSMUST00000050571.4
RIKEN cDNA A730020M07 gene
chr3_+_97628804 0.10 ENSMUST00000107050.1
ENSMUST00000029729.8
ENSMUST00000107049.1
flavin containing monooxygenase 5
chr1_-_139858684 0.09 ENSMUST00000094489.3
complement factor H-related 2
chr6_-_28397999 0.09 ENSMUST00000035930.4
zinc finger protein 800
chr7_-_46672537 0.09 ENSMUST00000049298.7
tryptophan hydroxylase 1
chr6_-_131313827 0.09 ENSMUST00000049150.1
serine/threonine/tyrosine kinase 1
chr2_+_69219971 0.09 ENSMUST00000005364.5
ENSMUST00000112317.2
glucose-6-phosphatase, catalytic, 2
chrX_-_169187200 0.09 ENSMUST00000066112.5
ENSMUST00000112118.1
ENSMUST00000112120.1
ENSMUST00000112119.1
amelogenin, X-linked
chr2_+_144270900 0.09 ENSMUST00000028910.2
ENSMUST00000110027.1
mitochondrial genome maintainance exonuclease 1
chr1_+_58802492 0.09 ENSMUST00000165549.1
caspase 8
chr4_+_98726734 0.09 ENSMUST00000152889.2
ENSMUST00000154279.2
LINE-1 type transposase domain containing 1
chr7_-_44744230 0.09 ENSMUST00000149011.1
zinc finger protein 473
chr7_-_3898120 0.09 ENSMUST00000070639.7
predicted gene 14548
chr1_+_140443101 0.09 ENSMUST00000145077.1
potassium channel, subfamily T, member 2
chr14_+_123659971 0.09 ENSMUST00000049681.7
integrin, beta-like 1
chr9_+_109832749 0.09 ENSMUST00000147777.1
ENSMUST00000035053.5
ENSMUST00000133483.1
NME/NM23 nucleoside diphosphate kinase 6
chr2_-_119271202 0.08 ENSMUST00000037360.7
ras homolog gene family, member V
chr7_-_133702515 0.08 ENSMUST00000153698.1
uroporphyrinogen III synthase
chr2_+_176807362 0.08 ENSMUST00000179435.1
predicted gene 14295
chr3_-_75451818 0.08 ENSMUST00000178270.1
WD repeat domain 49
chr1_-_162813926 0.08 ENSMUST00000144916.1
ENSMUST00000140274.1
flavin containing monooxygenase 4
chr2_-_30967859 0.08 ENSMUST00000028200.8
torsin family 1, member A (torsin A)
chr3_+_27317028 0.08 ENSMUST00000046383.5
ENSMUST00000174840.1
tumor necrosis factor (ligand) superfamily, member 10
chr10_-_127121125 0.08 ENSMUST00000164259.1
ENSMUST00000080975.4
amplified in osteosarcoma
chrX_-_164980310 0.08 ENSMUST00000004715.1
ENSMUST00000112248.2
motile sperm domain containing 2
chr11_-_99979053 0.08 ENSMUST00000105051.1
keratin associated protein 29-1
chr11_+_49794157 0.08 ENSMUST00000020629.4
glutamine fructose-6-phosphate transaminase 2
chr1_-_169969143 0.08 ENSMUST00000027989.6
ENSMUST00000111353.3
hydroxysteroid (17-beta) dehydrogenase 7
chr5_+_75152274 0.08 ENSMUST00000000476.8
platelet derived growth factor receptor, alpha polypeptide
chr8_+_129118043 0.08 ENSMUST00000108744.1
RIKEN cDNA 1700008F21 gene
chr18_+_37447641 0.08 ENSMUST00000052387.3
protocadherin beta 14
chr3_-_137552622 0.08 ENSMUST00000068546.5
predicted gene 4861
chr7_+_128129536 0.08 ENSMUST00000033053.6
integrin alpha X
chr10_-_30618337 0.08 ENSMUST00000019925.5
histidine triad nucleotide binding protein 3
chr5_+_30013141 0.08 ENSMUST00000026845.7
interleukin 6
chr8_+_92901387 0.07 ENSMUST00000104947.2
calpain, small subunit 2
chr3_-_15332285 0.07 ENSMUST00000108361.1
predicted gene 9733
chr9_+_89199209 0.07 ENSMUST00000068569.4
B cell leukemia/lymphoma 2 related protein A1b
chr11_+_81860679 0.07 ENSMUST00000021044.3
RIKEN cDNA 5530401A14 gene
chr12_-_118198917 0.07 ENSMUST00000084806.6
dynein, axonemal, heavy chain 11
chr8_+_60655540 0.07 ENSMUST00000034066.3
microfibrillar-associated protein 3-like
chr17_+_37193889 0.07 ENSMUST00000038844.6
ubiquitin D
chr7_-_126396715 0.07 ENSMUST00000075671.4
nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2 interacting protein
chrX_-_72274747 0.07 ENSMUST00000064780.3
gamma-aminobutyric acid (GABA) A receptor, subunit epsilon
chr6_+_138140521 0.07 ENSMUST00000120939.1
ENSMUST00000120302.1
microsomal glutathione S-transferase 1
chr8_+_10272572 0.07 ENSMUST00000042103.8
myosin XVI
chr6_-_85069449 0.07 ENSMUST00000160783.1
ENSMUST00000160197.1
exocyst complex component 6B
chr13_+_23839445 0.07 ENSMUST00000091698.4
ENSMUST00000110422.1
solute carrier family 17 (sodium phosphate), member 3
chr4_-_139131058 0.07 ENSMUST00000143971.1
mitochondrial inner membrane organizing system 1
chr14_-_68582078 0.07 ENSMUST00000022641.7
ADAM-like, decysin 1
chr6_-_116716888 0.07 ENSMUST00000056623.6
transmembrane protein 72
chr9_+_109832998 0.06 ENSMUST00000119376.1
ENSMUST00000122343.1
NME/NM23 nucleoside diphosphate kinase 6
chr19_-_57118981 0.06 ENSMUST00000111528.1
ENSMUST00000111529.1
ENSMUST00000104902.2
actin-binding LIM protein 1
chr8_+_104250869 0.06 ENSMUST00000034342.5
chemokine-like factor
chr2_+_69790968 0.06 ENSMUST00000180290.1
phosphatase, orphan 2
chr11_+_43151599 0.06 ENSMUST00000077659.5
ATPase, class V, type 10B
chrX_+_8271133 0.06 ENSMUST00000127103.1
ENSMUST00000115591.1
solute carrier family 38, member 5
chr7_+_43791891 0.06 ENSMUST00000005891.5
kallikrein related-peptidase 9
chr14_+_74640840 0.06 ENSMUST00000036653.3
5-hydroxytryptamine (serotonin) receptor 2A
chr7_+_23983961 0.06 ENSMUST00000077386.4
vomeronasal 1 receptor 181
chr8_+_55940453 0.06 ENSMUST00000000275.7
glycine receptor, alpha 3 subunit
chr18_+_51117754 0.06 ENSMUST00000116639.2
proline rich 16
chr3_-_108840477 0.06 ENSMUST00000106596.3
ENSMUST00000102621.4
syntaxin binding protein 3A
chr6_-_40951826 0.06 ENSMUST00000073642.5
predicted gene 4744
chr1_+_52630692 0.06 ENSMUST00000165859.1
transmembrane protein 194B
chrX_+_56346390 0.06 ENSMUST00000101560.3
zinc finger protein 449
chr14_+_3428103 0.06 ENSMUST00000178060.1
predicted gene 3005
chr16_-_52296924 0.06 ENSMUST00000167115.1
activated leukocyte cell adhesion molecule
chr7_-_3720382 0.06 ENSMUST00000078451.6
paired Ig-like receptor B
chr14_-_43875517 0.06 ENSMUST00000179200.1
eosinophil-associated, ribonuclease A family, member 1
chr10_+_61171954 0.06 ENSMUST00000122261.1
ENSMUST00000121297.1
ENSMUST00000035894.5
thymus, brain and testes associated
chr1_-_66863265 0.06 ENSMUST00000027153.5
acyl-Coenzyme A dehydrogenase, long-chain
chr8_+_53511695 0.06 ENSMUST00000033920.4
aspartylglucosaminidase
chr17_-_56512476 0.06 ENSMUST00000052211.2
zinc and ring finger 4
chr7_+_50599180 0.06 ENSMUST00000119710.2
RIKEN cDNA 4933405O20 gene
chr2_-_126783416 0.06 ENSMUST00000130356.1
ENSMUST00000028842.2
ubiquitin specific peptidase 50
chr2_-_119760295 0.05 ENSMUST00000082130.6
ENSMUST00000028759.6
leukocyte tyrosine kinase
chr1_-_53706775 0.05 ENSMUST00000094964.5
dynein, axonemal, heavy chain 7A
chrX_-_38456407 0.05 ENSMUST00000074913.5
ENSMUST00000016678.7
ENSMUST00000061755.8
lysosomal-associated membrane protein 2
chr2_-_79908389 0.05 ENSMUST00000090756.4
phosphodiesterase 1A, calmodulin-dependent
chr6_-_118139094 0.05 ENSMUST00000049344.8
chondroitin sulfate N-acetylgalactosaminyltransferase 2
chr13_-_63398167 0.05 ENSMUST00000160735.1
Fanconi anemia, complementation group C
chr13_-_64129305 0.05 ENSMUST00000099441.4
solute carrier family 35, member D2
chr1_+_185332143 0.05 ENSMUST00000027916.6
ENSMUST00000151769.1
ENSMUST00000110965.1
bisphosphate 3'-nucleotidase 1
chr3_-_106167564 0.05 ENSMUST00000063062.8
chitinase 3-like 3
chr16_-_19983005 0.05 ENSMUST00000058839.8
kelch-like 6
chrX_-_73290515 0.05 ENSMUST00000088450.3
X-linked lymphocyte-regulated 5C
chr13_-_24761861 0.05 ENSMUST00000006898.3
ENSMUST00000110382.2
geminin
chr8_-_129221950 0.05 ENSMUST00000079272.6
RIKEN cDNA 2610044O15 gene
chr7_+_100537192 0.05 ENSMUST00000120454.1
cytochrome c oxidase assembly factor 4
chr10_+_80879720 0.05 ENSMUST00000105333.2
transmembrane protease, serine 9
chr4_+_147507600 0.05 ENSMUST00000063704.7
predicted gene 13152
chr14_+_67716262 0.05 ENSMUST00000150768.1
potassium channel tetramerisation domain containing 9
chr2_-_79908428 0.05 ENSMUST00000102652.3
ENSMUST00000102651.3
phosphodiesterase 1A, calmodulin-dependent
chr7_-_5351035 0.05 ENSMUST00000045022.7
NLR family, pyrin domain containing 2
chr4_+_152199805 0.05 ENSMUST00000105652.2
acyl-CoA thioesterase 7

Network of associatons between targets according to the STRING database.

First level regulatory network of Irx6_Irx2_Irx3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.1 0.4 GO:0032385 positive regulation of intracellular lipid transport(GO:0032379) positive regulation of intracellular sterol transport(GO:0032382) positive regulation of intracellular cholesterol transport(GO:0032385) lipid hydroperoxide transport(GO:1901373)
0.1 0.3 GO:1904000 positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100) positive regulation of cortisol secretion(GO:0051464) positive regulation of eating behavior(GO:1904000) positive regulation of small intestine smooth muscle contraction(GO:1904349)
0.1 0.2 GO:0001712 ectodermal cell fate commitment(GO:0001712) regulation of heart induction by regulation of canonical Wnt signaling pathway(GO:0090081)
0.1 0.4 GO:0002835 negative regulation of response to tumor cell(GO:0002835) negative regulation of immune response to tumor cell(GO:0002838)
0.1 0.2 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.1 0.2 GO:1901475 pyruvate transmembrane transport(GO:1901475)
0.1 0.5 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0 0.4 GO:0097033 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.1 GO:1904139 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.0 0.2 GO:2000065 negative regulation of aldosterone metabolic process(GO:0032345) negative regulation of aldosterone biosynthetic process(GO:0032348) negative regulation of cortisol biosynthetic process(GO:2000065)
0.0 0.2 GO:0015671 oxygen transport(GO:0015671)
0.0 0.2 GO:0090206 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0 0.1 GO:0072276 metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.0 0.3 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 0.2 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.0 0.1 GO:0006780 uroporphyrinogen III biosynthetic process(GO:0006780)
0.0 0.4 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.0 0.1 GO:0007208 phospholipase C-activating serotonin receptor signaling pathway(GO:0007208)
0.0 0.1 GO:1900244 positive regulation of synaptic vesicle endocytosis(GO:1900244)
0.0 0.5 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.0 0.1 GO:0071211 protein targeting to vacuole involved in autophagy(GO:0071211)
0.0 0.1 GO:2001280 positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.0 0.1 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.0 0.1 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 0.2 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.2 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.1 GO:0015747 urate transport(GO:0015747)
0.0 0.1 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.0 0.0 GO:2001205 negative regulation of osteoclast development(GO:2001205)
0.0 0.1 GO:0042737 drug catabolic process(GO:0042737)
0.0 0.1 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.2 GO:1901629 regulation of presynaptic membrane organization(GO:1901629)
0.0 0.1 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.0 0.2 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.0 0.1 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.0 0.1 GO:0060336 negative regulation of response to interferon-gamma(GO:0060331) negative regulation of interferon-gamma-mediated signaling pathway(GO:0060336)
0.0 0.0 GO:0090004 positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.0 0.0 GO:1900535 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.0 0.0 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.1 GO:0015074 DNA integration(GO:0015074)
0.0 0.1 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.0 GO:0051697 protein delipidation(GO:0051697)
0.0 0.1 GO:0050651 dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.0 0.1 GO:1901162 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.0 0.0 GO:0030043 actin filament fragmentation(GO:0030043)
0.0 0.0 GO:0032685 negative regulation of granulocyte macrophage colony-stimulating factor production(GO:0032685)
0.0 0.1 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0005663 DNA replication factor C complex(GO:0005663)
0.1 0.5 GO:0000801 central element(GO:0000801)
0.0 0.4 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0 0.1 GO:0030690 Noc1p-Noc2p complex(GO:0030690)
0.0 0.1 GO:0097422 tubular endosome(GO:0097422)
0.0 0.1 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.1 GO:0031088 platelet dense granule membrane(GO:0031088) intrinsic component of autophagosome membrane(GO:0097636) integral component of autophagosome membrane(GO:0097637)
0.0 0.1 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.1 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 0.4 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.2 GO:0001533 cornified envelope(GO:0001533)
0.0 0.1 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.1 GO:0000836 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0045352 interleukin-1, Type II receptor binding(GO:0005151) interleukin-1 receptor antagonist activity(GO:0005152) interleukin-1 Type I receptor antagonist activity(GO:0045352) interleukin-1 Type II receptor antagonist activity(GO:0045353)
0.1 0.4 GO:0050632 propanoyl-CoA C-acyltransferase activity(GO:0033814) propionyl-CoA C2-trimethyltridecanoyltransferase activity(GO:0050632) phosphatidylethanolamine transporter activity(GO:1904121)
0.1 0.4 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.1 0.4 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 0.2 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.1 0.2 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.1 0.2 GO:0070401 androsterone dehydrogenase activity(GO:0047023) NADP+ binding(GO:0070401) lithocholic acid binding(GO:1902121)
0.1 0.3 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 0.5 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 0.5 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.2 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.1 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0 0.1 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.0 0.2 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.1 GO:0005093 Rab GDP-dissociation inhibitor activity(GO:0005093)
0.0 0.1 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.0 0.1 GO:0035877 death effector domain binding(GO:0035877)
0.0 0.2 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 0.3 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.1 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.0 0.1 GO:0046848 hydroxyapatite binding(GO:0046848)
0.0 0.1 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.0 0.1 GO:0033883 pyridoxal phosphatase activity(GO:0033883)
0.0 0.1 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.0 0.1 GO:0034452 dynactin binding(GO:0034452)
0.0 0.1 GO:0048101 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.1 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.0 0.1 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.1 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 0.1 GO:0047237 glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237)
0.0 0.1 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.2 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.0 GO:0005502 11-cis retinal binding(GO:0005502)
0.0 0.1 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.3 GO:0008252 nucleotidase activity(GO:0008252)
0.0 0.1 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.1 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.4 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814)
0.0 0.0 GO:0004492 methylmalonyl-CoA decarboxylase activity(GO:0004492)
0.0 0.4 GO:0043236 laminin binding(GO:0043236)
0.0 0.0 GO:0004769 steroid delta-isomerase activity(GO:0004769)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.4 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.0 0.5 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.3 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.4 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0 0.4 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.2 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.8 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.2 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.2 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.2 REACTOME GLUCURONIDATION Genes involved in Glucuronidation