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12D miR HR13_24

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Results for Foxa3

Z-value: 1.55

Motif logo

Transcription factors associated with Foxa3

Gene Symbol Gene ID Gene Info
ENSMUSG00000040891.5 forkhead box A3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Foxa3mm10_v2_chr7_-_19023538_190235460.539.1e-02Click!

Activity profile of Foxa3 motif

Sorted Z-values of Foxa3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_104766308 8.31 ENSMUST00000031663.3
complement component 8, beta polypeptide
chr4_+_104766334 7.71 ENSMUST00000065072.6
complement component 8, beta polypeptide
chrX_-_108664891 6.80 ENSMUST00000178160.1
predicted gene 379
chr3_+_138277489 3.64 ENSMUST00000004232.9
alcohol dehydrogenase 1 (class I)
chr13_-_95478655 3.32 ENSMUST00000022186.3
S100 calcium binding protein, zeta
chr2_-_62483637 2.87 ENSMUST00000136686.1
ENSMUST00000102733.3
glucagon
chr5_-_86906937 2.68 ENSMUST00000031181.9
ENSMUST00000113333.1
UDP glucuronosyltransferase 2 family, polypeptide B34
chr3_+_106113229 2.33 ENSMUST00000079132.5
ENSMUST00000139086.1
chitinase, acidic
chr6_+_97991776 2.29 ENSMUST00000043628.6
microphthalmia-associated transcription factor
chr3_-_145032765 2.23 ENSMUST00000029919.5
chloride channel calcium activated 3
chr11_-_99993992 2.16 ENSMUST00000105049.1
keratin associated protein 17-1
chr11_-_99986593 2.02 ENSMUST00000105050.2
keratin associated protein 16-1
chr8_+_107119110 1.98 ENSMUST00000046116.1
RIKEN cDNA C630050I24 gene
chr8_+_106603351 1.80 ENSMUST00000000312.5
ENSMUST00000167688.1
cadherin 1
chr14_-_110755100 1.79 ENSMUST00000078386.2
SLIT and NTRK-like family, member 6
chr14_-_41185188 1.75 ENSMUST00000077136.3
surfactant associated protein D
chr4_-_57916283 1.74 ENSMUST00000063816.5
RIKEN cDNA D630039A03 gene
chrX_+_164140447 1.74 ENSMUST00000073973.4
angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
chr6_+_5390387 1.71 ENSMUST00000183358.1
ankyrin repeat and SOCS box-containing 4
chr3_-_113258837 1.67 ENSMUST00000098673.3
amylase 2a5
chr17_-_31144271 1.56 ENSMUST00000024826.7
trefoil factor 2 (spasmolytic protein 1)
chr16_-_45492962 1.51 ENSMUST00000114585.2
predicted gene 609
chr8_+_105427634 1.50 ENSMUST00000067305.6
leucine rich repeat containing 36
chr2_+_58755177 1.46 ENSMUST00000102755.3
uridine phosphorylase 2
chr16_+_17331371 1.45 ENSMUST00000023450.6
ENSMUST00000161034.1
serine (or cysteine) peptidase inhibitor, clade D, member 1
chr7_+_131032061 1.41 ENSMUST00000084509.3
deleted in malignant brain tumors 1
chr9_+_53301571 1.40 ENSMUST00000051014.1
exophilin 5
chr17_+_70522083 1.40 ENSMUST00000148486.1
ENSMUST00000133717.1
discs, large (Drosophila) homolog-associated protein 1
chr9_+_98490522 1.37 ENSMUST00000035029.2
retinol binding protein 2, cellular
chr14_-_30943275 1.35 ENSMUST00000006704.8
ENSMUST00000163118.1
inter-alpha trypsin inhibitor, heavy chain 1
chr11_-_100146120 1.34 ENSMUST00000007317.7
keratin 19
chr2_+_58754910 1.33 ENSMUST00000059102.6
uridine phosphorylase 2
chr3_-_106406090 1.30 ENSMUST00000029510.7
cDNA sequence BC051070
chr5_-_108795352 1.29 ENSMUST00000004943.1
transmembrane emp24 protein transport domain containing
chrX_+_140907602 1.24 ENSMUST00000033806.4
V-set and immunoglobulin domain containing 1
chr19_-_58454435 1.16 ENSMUST00000169850.1
glial cell line derived neurotrophic factor family receptor alpha 1
chr3_-_113532288 1.14 ENSMUST00000132353.1
amylase 2a1
chr2_-_104742802 1.12 ENSMUST00000028595.7
DEP domain containing 7
chr4_+_45965327 1.11 ENSMUST00000107777.2
tudor domain containing 7
chr10_+_127898515 1.07 ENSMUST00000047134.7
4short chain dehydrogenase/reductase family 9C, member 7
chr6_+_139621888 1.06 ENSMUST00000032353.8
phosphatidylinositol 3-kinase, C2 domain containing, gamma polypeptide
chr3_-_106167564 1.05 ENSMUST00000063062.8
chitinase 3-like 3
chr17_+_34969912 1.04 ENSMUST00000173680.1
predicted gene 20481
chr13_+_23738804 1.03 ENSMUST00000040914.1
histone cluster 1, H1c
chr1_+_110099295 1.00 ENSMUST00000134301.1
cadherin 7, type 2
chr2_+_164403194 0.99 ENSMUST00000017151.1
recombination signal binding protein for immunoglobulin kappa J region-like
chr2_+_24345305 0.99 ENSMUST00000114482.1
interleukin 1 receptor antagonist
chr3_-_20275659 0.97 ENSMUST00000011607.5
carboxypeptidase B1 (tissue)
chr4_-_127354074 0.97 ENSMUST00000106090.1
ENSMUST00000060419.1
gap junction protein, beta 4
chr2_-_170194033 0.97 ENSMUST00000180625.1
predicted gene, 17619
chrX_+_139563316 0.92 ENSMUST00000113027.1
ring finger protein 128
chr3_+_3508024 0.89 ENSMUST00000108393.1
ENSMUST00000017832.8
hepatocyte nuclear factor 4, gamma
chr1_+_43445736 0.85 ENSMUST00000086421.5
ENSMUST00000114744.1
non-catalytic region of tyrosine kinase adaptor protein 2
chr5_-_103211251 0.85 ENSMUST00000060871.5
ENSMUST00000112846.1
ENSMUST00000170792.1
ENSMUST00000112847.2
mitogen-activated protein kinase 10
chr2_+_24345282 0.81 ENSMUST00000114485.2
interleukin 1 receptor antagonist
chr10_-_93310963 0.80 ENSMUST00000151153.1
ELK3, member of ETS oncogene family
chr17_+_70522149 0.78 ENSMUST00000140728.1
discs, large (Drosophila) homolog-associated protein 1
chr13_-_13393592 0.77 ENSMUST00000021738.8
G protein-coupled receptor 137B
chr11_-_69805617 0.76 ENSMUST00000051025.4
transmembrane protein 102
chr1_+_157526127 0.75 ENSMUST00000111700.1
SEC16 homolog B (S. cerevisiae)
chr4_-_25281752 0.73 ENSMUST00000038705.7
UFM1 specific ligase 1
chr16_-_43664145 0.73 ENSMUST00000096065.4
T cell immunoreceptor with Ig and ITIM domains
chr12_+_59131473 0.73 ENSMUST00000177162.1
CTAGE family, member 5
chr6_-_137571007 0.72 ENSMUST00000100841.2
epidermal growth factor receptor pathway substrate 8
chr4_-_58499398 0.72 ENSMUST00000107570.1
lysophosphatidic acid receptor 1
chr13_-_74807913 0.71 ENSMUST00000065629.4
calpastatin
chr6_-_40951826 0.70 ENSMUST00000073642.5
predicted gene 4744
chr1_+_88166004 0.70 ENSMUST00000097659.4
UDP glucuronosyltransferase 1 family, polypeptide A5
chr19_+_20601958 0.69 ENSMUST00000087638.3
aldehyde dehydrogenase family 1, subfamily A1
chr5_+_102481374 0.67 ENSMUST00000094559.2
ENSMUST00000073302.5
Rho GTPase activating protein 24
chr10_-_93311073 0.67 ENSMUST00000008542.5
ELK3, member of ETS oncogene family
chr19_+_26623419 0.64 ENSMUST00000176584.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr5_+_102481546 0.63 ENSMUST00000112854.1
Rho GTPase activating protein 24
chr19_-_20727533 0.62 ENSMUST00000025656.3
aldehyde dehydrogenase family 1, subfamily A7
chr15_-_95830072 0.61 ENSMUST00000168960.1
predicted gene, 17546
chr19_+_29951808 0.60 ENSMUST00000136850.1
interleukin 33
chr13_+_40859768 0.60 ENSMUST00000110191.2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme
chr15_-_3303521 0.60 ENSMUST00000165386.1
coiled-coil domain containing 152
chr16_+_36156801 0.58 ENSMUST00000079184.4
stefin A2 like 1
chr10_-_128744014 0.58 ENSMUST00000026414.7
diacylglycerol kinase, alpha
chr9_+_109931458 0.58 ENSMUST00000072772.5
ENSMUST00000035055.8
microtubule-associated protein 4
chr12_+_71016658 0.58 ENSMUST00000125125.1
AT rich interactive domain 4A (RBP1-like)
chr11_-_99438143 0.56 ENSMUST00000017743.2
keratin 20
chr16_+_49699198 0.56 ENSMUST00000046777.4
ENSMUST00000142682.1
intraflagellar transport 57
chr12_+_8012359 0.55 ENSMUST00000171239.1
apolipoprotein B
chr18_-_62756275 0.55 ENSMUST00000067450.1
ENSMUST00000048109.5
RIKEN cDNA 2700046A07 gene
chrX_-_141725181 0.55 ENSMUST00000067841.7
insulin receptor substrate 4
chr5_-_5664196 0.55 ENSMUST00000061008.3
ENSMUST00000054865.6
RIKEN cDNA A330021E22 gene
chr3_+_96219858 0.53 ENSMUST00000073115.4
histone cluster 2, H2ab
chr18_-_38918642 0.53 ENSMUST00000040647.4
fibroblast growth factor 1
chr2_-_90479165 0.52 ENSMUST00000111495.2
protein tyrosine phosphatase, receptor type, J
chr15_-_101869695 0.51 ENSMUST00000087996.5
keratin 77
chr1_-_156034826 0.50 ENSMUST00000141878.1
ENSMUST00000123705.1
torsin A interacting protein 1
chr16_-_88563166 0.49 ENSMUST00000049697.4
claudin 8
chr4_-_63154130 0.49 ENSMUST00000030041.4
alpha 1 microglobulin/bikunin
chr17_-_12675833 0.48 ENSMUST00000024596.8
solute carrier family 22 (organic cation transporter), member 1
chr18_+_37742088 0.47 ENSMUST00000003599.6
protocadherin gamma subfamily A, 9
chr15_-_54920115 0.46 ENSMUST00000171545.1
ectonucleotide pyrophosphatase/phosphodiesterase 2
chrX_+_142227923 0.45 ENSMUST00000042329.5
nuclear transport factor 2-like export factor 2
chr11_+_69364010 0.45 ENSMUST00000166700.1
predicted gene, 17305
chr12_+_7977640 0.45 ENSMUST00000171271.1
ENSMUST00000037811.6
ENSMUST00000037520.7
apolipoprotein B
chr4_-_55532453 0.44 ENSMUST00000132746.1
ENSMUST00000107619.2
Kruppel-like factor 4 (gut)
chr11_-_69197809 0.44 ENSMUST00000094078.3
ENSMUST00000021262.3
arachidonate 8-lipoxygenase
chr11_-_46389454 0.44 ENSMUST00000101306.3
IL2 inducible T cell kinase
chr3_+_134236483 0.44 ENSMUST00000181904.1
ENSMUST00000053048.9
CXXC finger 4
chrX_+_142228177 0.44 ENSMUST00000112914.1
nuclear transport factor 2-like export factor 2
chr14_+_46832127 0.44 ENSMUST00000068532.8
cell growth regulator with ring finger domain 1
chr2_+_143915273 0.43 ENSMUST00000103172.3
destrin
chr7_-_34655500 0.43 ENSMUST00000032709.1
potassium channel tetramerisation domain containing 15
chr12_+_84451485 0.43 ENSMUST00000137170.1
lin-52 homolog (C. elegans)
chr12_+_55089202 0.42 ENSMUST00000021407.10
signal recognition particle 54A
chr18_+_36952621 0.41 ENSMUST00000115661.2
protocadherin alpha 2
chr4_-_121109199 0.41 ENSMUST00000106268.3
transmembrane and coiled-coil domains 2
chr12_+_119443410 0.41 ENSMUST00000048880.6
metastasis associated in colon cancer 1
chr4_+_150853919 0.39 ENSMUST00000073600.2
ERBB receptor feedback inhibitor 1
chr8_+_11556061 0.39 ENSMUST00000054399.4
inhibitor of growth family, member 1
chr15_+_102407144 0.38 ENSMUST00000169619.1
trans-acting transcription factor 1
chr12_-_84450944 0.38 ENSMUST00000085192.5
aldehyde dehydrogenase family 6, subfamily A1
chr2_-_163645125 0.37 ENSMUST00000017851.3
serine incorporator 3
chr7_+_30565410 0.36 ENSMUST00000043850.7
IGF-like family receptor 1
chr12_-_57546121 0.35 ENSMUST00000044380.6
forkhead box A1
chr19_-_8713862 0.35 ENSMUST00000010239.4
solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2
chr7_+_30458280 0.34 ENSMUST00000126297.1
nephrosis 1, nephrin
chrX_+_129749830 0.34 ENSMUST00000113320.2
diaphanous homolog 2 (Drosophila)
chr6_+_34863130 0.34 ENSMUST00000074949.3
transmembrane protein 140
chr15_-_5108492 0.33 ENSMUST00000118365.2
caspase recruitment domain family, member 6
chr1_+_165763746 0.33 ENSMUST00000111432.3
cellular repressor of E1A-stimulated genes 1
chr8_+_70373541 0.33 ENSMUST00000003659.7
cartilage oligomeric matrix protein
chr1_+_93373874 0.31 ENSMUST00000058682.4
anoctamin 7
chr10_-_52195244 0.31 ENSMUST00000020045.3
Ros1 proto-oncogene
chr15_-_54919961 0.29 ENSMUST00000167541.2
ENSMUST00000041591.9
ENSMUST00000173516.1
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr14_-_49245389 0.29 ENSMUST00000130853.1
ENSMUST00000022398.7
RIKEN cDNA 1700011H14 gene
chr2_+_80617045 0.29 ENSMUST00000028384.4
dual specificity phosphatase 19
chr9_-_101198999 0.28 ENSMUST00000066773.7
protein phosphatase 2, regulatory subunit B'', alpha
chr18_+_67133713 0.28 ENSMUST00000076605.7
guanine nucleotide binding protein, alpha stimulating, olfactory type
chr2_-_126500631 0.27 ENSMUST00000129187.1
ATPase, class I, type 8B, member 4
chr12_-_87200200 0.27 ENSMUST00000037418.5
transmembrane emp24 domain containing 8
chr1_+_17145357 0.27 ENSMUST00000026879.7
ganglioside-induced differentiation-associated-protein 1
chr18_-_88927447 0.26 ENSMUST00000147313.1
suppressor of cytokine signaling 6
chr2_-_77519565 0.26 ENSMUST00000111830.2
zinc finger protein 385B
chr5_+_90561102 0.26 ENSMUST00000094615.4
RIKEN cDNA 5830473C10 gene
chr10_+_21992216 0.26 ENSMUST00000150089.1
ENSMUST00000100036.3
serum/glucocorticoid regulated kinase 1
chr1_-_170867761 0.25 ENSMUST00000027974.6
activating transcription factor 6
chr8_-_47713920 0.25 ENSMUST00000038738.5
CDKN2A interacting protein
chr10_+_21690845 0.25 ENSMUST00000071008.3
predicted gene 5420
chr16_-_29378667 0.24 ENSMUST00000143373.1
ENSMUST00000075806.4
ATPase type 13A5
chr11_-_69662625 0.24 ENSMUST00000018905.5
mannose-P-dolichol utilization defect 1
chr5_+_88487982 0.24 ENSMUST00000031222.8
enamelin
chr11_+_77765588 0.24 ENSMUST00000164315.1
myosin XVIIIA
chr3_-_89764581 0.23 ENSMUST00000029562.3
cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal)
chr12_-_31950535 0.23 ENSMUST00000172314.2
high mobility group box transcription factor 1
chr12_+_87200524 0.22 ENSMUST00000182869.1
sterile alpha motif domain containing 15
chr17_+_34238914 0.22 ENSMUST00000167280.1
histocompatibility 2, O region beta locus
chr10_+_96616998 0.22 ENSMUST00000038377.7
B cell translocation gene 1, anti-proliferative
chr11_+_46810792 0.21 ENSMUST00000068877.6
T cell immunoglobulin and mucin domain containing 4
chr4_-_36056726 0.21 ENSMUST00000108124.3
leucine rich repeat and Ig domain containing 2
chr11_-_54860564 0.21 ENSMUST00000144164.1
LYR motif containing 7
chr6_+_41860239 0.21 ENSMUST00000014248.4
seminal vesicle antigen-like 2
chr15_-_5108469 0.21 ENSMUST00000141020.1
caspase recruitment domain family, member 6
chr4_+_139653538 0.20 ENSMUST00000030510.7
ENSMUST00000166773.1
taste receptor, type 1, member 2
chr11_-_76027726 0.20 ENSMUST00000021207.6
family with sequence similarity 101, member B
chr2_+_91730127 0.20 ENSMUST00000099712.3
ENSMUST00000111317.2
ENSMUST00000111316.2
ENSMUST00000045705.7
autophagy/beclin 1 regulator 1
chr3_-_144202300 0.19 ENSMUST00000121796.1
ENSMUST00000121112.1
LIM domain only 4
chr7_-_65371210 0.19 ENSMUST00000102592.3
tight junction protein 1
chr10_+_23851454 0.19 ENSMUST00000020190.7
vanin 3
chr15_-_99820072 0.18 ENSMUST00000109024.2
LIM domain and actin binding 1
chr18_+_23752333 0.18 ENSMUST00000170802.1
ENSMUST00000155708.1
ENSMUST00000118826.2
microtubule-associated protein, RP/EB family, member 2
chr10_-_57532489 0.18 ENSMUST00000020027.4
serine incorporator 1
chrX_-_75578188 0.18 ENSMUST00000033545.5
RAB39B, member RAS oncogene family
chr17_-_42611313 0.17 ENSMUST00000068355.6
opsin 5
chr3_-_155055341 0.17 ENSMUST00000064076.3
TNNI3 interacting kinase
chr11_+_65162132 0.17 ENSMUST00000181156.1
RIKEN cDNA B430202K04 gene
chr1_-_13374072 0.17 ENSMUST00000068304.6
ENSMUST00000006037.6
nuclear receptor coactivator 2
chr19_-_58455903 0.16 ENSMUST00000131877.1
glial cell line derived neurotrophic factor family receptor alpha 1
chr11_+_96133786 0.16 ENSMUST00000167258.1
tubulin tyrosine ligase-like family, member 6
chr2_+_52072823 0.15 ENSMUST00000112693.2
ENSMUST00000069794.5
Rap1 interacting factor 1 homolog (yeast)
chr1_-_180245757 0.15 ENSMUST00000111104.1
presenilin 2
chr3_-_146781351 0.14 ENSMUST00000005164.7
protein kinase, cAMP dependent, catalytic, beta
chr19_-_37207293 0.14 ENSMUST00000132580.1
ENSMUST00000079754.4
ENSMUST00000136286.1
ENSMUST00000126188.1
ENSMUST00000126781.1
cytoplasmic polyadenylation element binding protein 3
chr7_+_102229999 0.14 ENSMUST00000120119.1
post-GPI attachment to proteins 2
chr9_-_71163224 0.13 ENSMUST00000074465.2
aquaporin 9
chr2_-_126499839 0.13 ENSMUST00000040128.5
ATPase, class I, type 8B, member 4
chr2_+_173737492 0.13 ENSMUST00000067530.4
vesicle-associated membrane protein, associated protein B and C
chr2_+_153161303 0.13 ENSMUST00000089027.2
transmembrane 9 superfamily protein member 4
chr17_+_47505211 0.13 ENSMUST00000182935.1
ENSMUST00000182506.1
cyclin D3
chr1_+_75142775 0.13 ENSMUST00000097694.4
family with sequence similarity 134, member A
chr1_-_168431695 0.12 ENSMUST00000176790.1
pre B cell leukemia homeobox 1
chr9_-_99710063 0.12 ENSMUST00000035048.5
claudin 18
chr10_-_128919259 0.12 ENSMUST00000149961.1
ENSMUST00000026406.7
retinol dehydrogenase 5
chr15_-_81104999 0.12 ENSMUST00000109579.2
MKL (megakaryoblastic leukemia)/myocardin-like 1
chr7_+_19228334 0.12 ENSMUST00000063976.8
optic atrophy 3
chr2_+_164833781 0.11 ENSMUST00000143780.1
cathepsin A
chr11_+_78465697 0.11 ENSMUST00000001126.3
solute carrier family 46, member 1
chr6_-_145434925 0.11 ENSMUST00000111708.2
intermediate filament tail domain containing 1
chr11_-_69662564 0.11 ENSMUST00000129224.1
ENSMUST00000155200.1
mannose-P-dolichol utilization defect 1
chr7_-_84679346 0.11 ENSMUST00000069537.2
ENSMUST00000178385.1
zinc finger, AN1-type domain 6
chr10_+_97565436 0.10 ENSMUST00000038160.4
lumican
chr4_+_42916647 0.10 ENSMUST00000132173.1
ENSMUST00000107975.1
expressed sequence N28178
chr11_-_42000532 0.10 ENSMUST00000070735.3
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2
chr1_-_66935333 0.09 ENSMUST00000120415.1
ENSMUST00000119429.1
myosin, light polypeptide 1

Network of associatons between targets according to the STRING database.

First level regulatory network of Foxa3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 16.0 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.9 3.7 GO:0006069 ethanol oxidation(GO:0006069)
0.4 1.8 GO:0060005 vestibular reflex(GO:0060005)
0.4 1.8 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.4 1.7 GO:0015801 aromatic amino acid transport(GO:0015801) tryptophan transport(GO:0015827)
0.4 2.9 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.4 1.8 GO:0060066 oviduct development(GO:0060066)
0.4 1.8 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.3 1.6 GO:0060455 negative regulation of gastric acid secretion(GO:0060455)
0.2 1.4 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.2 2.3 GO:0044336 canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
0.2 0.7 GO:1903898 positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493) negative regulation of PERK-mediated unfolded protein response(GO:1903898)
0.2 0.7 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.2 0.7 GO:1904566 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.2 2.2 GO:0070842 aggresome assembly(GO:0070842)
0.2 1.3 GO:0006776 vitamin A metabolic process(GO:0006776)
0.2 1.7 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.1 1.0 GO:0016584 nucleosome positioning(GO:0016584)
0.1 1.3 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.1 0.8 GO:0007258 JUN phosphorylation(GO:0007258)
0.1 0.4 GO:0006210 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.1 0.7 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.1 0.5 GO:0010248 establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.1 0.6 GO:0002282 microglial cell activation involved in immune response(GO:0002282)
0.1 0.6 GO:0036438 maintenance of lens transparency(GO:0036438)
0.1 0.4 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743) alveolar secondary septum development(GO:0061144)
0.1 0.6 GO:0051012 microtubule sliding(GO:0051012)
0.1 0.4 GO:0045415 regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900) negative regulation of interleukin-8 biosynthetic process(GO:0045415) positive regulation of core promoter binding(GO:1904798)
0.1 1.0 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
0.1 0.4 GO:0030043 actin filament fragmentation(GO:0030043)
0.1 0.7 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.1 0.5 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.1 0.7 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.1 0.6 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.1 0.4 GO:0051121 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.1 0.2 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
0.1 0.2 GO:0070173 positive regulation of odontogenesis of dentin-containing tooth(GO:0042488) regulation of enamel mineralization(GO:0070173)
0.1 0.4 GO:0042536 negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.1 1.2 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.1 0.2 GO:0060084 synaptic transmission involved in micturition(GO:0060084)
0.1 0.7 GO:0048207 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.1 1.4 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.1 0.4 GO:0009597 detection of virus(GO:0009597)
0.1 0.6 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.1 0.3 GO:0007525 somatic muscle development(GO:0007525)
0.1 0.3 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.1 0.6 GO:0042573 retinoic acid metabolic process(GO:0042573)
0.1 1.0 GO:0042048 olfactory behavior(GO:0042048)
0.1 0.4 GO:0070814 hydrogen sulfide biosynthetic process(GO:0070814)
0.1 0.3 GO:0061589 calcium activated phosphatidylserine scrambling(GO:0061589)
0.1 0.9 GO:0010820 positive regulation of T cell chemotaxis(GO:0010820)
0.1 0.2 GO:1903027 regulation of opsonization(GO:1903027) positive regulation of opsonization(GO:1903028)
0.1 0.7 GO:2000675 egg activation(GO:0007343) negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.1 0.7 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.1 0.7 GO:0018298 protein-chromophore linkage(GO:0018298)
0.1 0.2 GO:0002587 negative regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002587)
0.1 0.3 GO:0010966 regulation of phosphate transport(GO:0010966)
0.1 0.5 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 1.2 GO:0039694 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.0 0.1 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.0 0.1 GO:1900248 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.0 0.3 GO:0009405 pathogenesis(GO:0009405)
0.0 0.6 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.0 0.1 GO:2001205 negative regulation of osteoclast development(GO:2001205)
0.0 0.2 GO:0015886 heme transport(GO:0015886)
0.0 0.2 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.0 0.7 GO:0032695 negative regulation of interleukin-12 production(GO:0032695)
0.0 0.6 GO:0001865 NK T cell differentiation(GO:0001865)
0.0 0.9 GO:0042036 negative regulation of cytokine biosynthetic process(GO:0042036)
0.0 0.2 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.0 0.1 GO:0015855 nucleobase transport(GO:0015851) pyrimidine nucleobase transport(GO:0015855)
0.0 1.1 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 1.4 GO:0060706 cell differentiation involved in embryonic placenta development(GO:0060706)
0.0 0.5 GO:0043116 negative regulation of vascular permeability(GO:0043116)
0.0 0.2 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.0 0.4 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 1.0 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.6 GO:0044458 motile cilium assembly(GO:0044458)
0.0 0.2 GO:0045925 positive regulation of female receptivity(GO:0045925)
0.0 0.3 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.1 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.0 0.6 GO:0045109 intermediate filament organization(GO:0045109)
0.0 0.3 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 2.5 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.2 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.0 0.3 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.2 GO:0003352 regulation of cilium movement(GO:0003352)
0.0 2.8 GO:0009166 nucleotide catabolic process(GO:0009166)
0.0 0.1 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.2 GO:0017062 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.2 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.2 GO:0086069 bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.0 0.1 GO:0015727 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.0 0.1 GO:0043589 skin morphogenesis(GO:0043589)
0.0 0.0 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
0.0 0.2 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.0 0.1 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.0 0.1 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.0 0.2 GO:0098780 response to mitochondrial depolarisation(GO:0098780)
0.0 0.3 GO:0044062 regulation of excretion(GO:0044062)
0.0 0.3 GO:0008053 mitochondrial fusion(GO:0008053)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 16.3 GO:0005579 membrane attack complex(GO:0005579)
0.3 2.8 GO:0045098 type III intermediate filament(GO:0045098)
0.2 1.7 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.2 1.4 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.2 1.3 GO:1990357 terminal web(GO:1990357)
0.1 1.8 GO:0016600 flotillin complex(GO:0016600) lateral loop(GO:0043219)
0.1 1.0 GO:0031983 vesicle lumen(GO:0031983)
0.1 2.5 GO:0045095 keratin filament(GO:0045095)
0.1 1.1 GO:0033391 chromatoid body(GO:0033391)
0.1 0.4 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.1 1.0 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 1.0 GO:0005922 connexon complex(GO:0005922)
0.0 1.8 GO:0005771 multivesicular body(GO:0005771)
0.0 0.4 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.7 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 1.1 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.2 GO:0001652 granular component(GO:0001652)
0.0 0.6 GO:0071564 npBAF complex(GO:0071564)
0.0 0.6 GO:0044292 dendrite terminus(GO:0044292)
0.0 0.2 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.7 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.3 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 2.2 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.1 GO:0001940 male pronucleus(GO:0001940)
0.0 0.2 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.2 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.1 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.0 GO:0044279 other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.0 0.8 GO:0001772 immunological synapse(GO:0001772)
0.0 0.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.4 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.6 GO:0005882 intermediate filament(GO:0005882)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.7 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.6 1.8 GO:0045352 interleukin-1, Type II receptor binding(GO:0005151) interleukin-1 receptor antagonist activity(GO:0005152) interleukin-1 Type I receptor antagonist activity(GO:0045352) interleukin-1 Type II receptor antagonist activity(GO:0045353)
0.6 2.8 GO:0004850 uridine phosphorylase activity(GO:0004850)
0.4 1.3 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.4 1.5 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.2 1.7 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.2 0.7 GO:0071568 UFM1 transferase activity(GO:0071568)
0.2 1.7 GO:0004556 alpha-amylase activity(GO:0004556)
0.2 0.8 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.2 0.5 GO:0005333 norepinephrine transmembrane transporter activity(GO:0005333)
0.1 0.6 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1 1.0 GO:0035473 lipase binding(GO:0035473)
0.1 0.7 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.1 1.6 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 1.4 GO:0019841 retinol binding(GO:0019841)
0.1 1.8 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 0.7 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.1 3.4 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 0.3 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 0.4 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.1 0.2 GO:0005502 11-cis retinal binding(GO:0005502)
0.1 0.4 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.1 1.2 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.1 1.1 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 1.8 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.1 0.5 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.3 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.6 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.6 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 2.3 GO:0070888 E-box binding(GO:0070888)
0.0 0.2 GO:0015232 heme transporter activity(GO:0015232)
0.0 1.0 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.5 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.5 GO:0019865 immunoglobulin binding(GO:0019865)
0.0 0.3 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 0.2 GO:0031013 troponin I binding(GO:0031013)
0.0 0.2 GO:0033142 progesterone receptor binding(GO:0033142)
0.0 0.1 GO:0005345 purine nucleobase transmembrane transporter activity(GO:0005345) pyrimidine nucleobase transmembrane transporter activity(GO:0005350) nucleobase transmembrane transporter activity(GO:0015205) glycerol channel activity(GO:0015254)
0.0 1.3 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 1.1 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.2 GO:0008527 taste receptor activity(GO:0008527)
0.0 0.1 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.5 GO:0005521 lamin binding(GO:0005521)
0.0 0.1 GO:0023025 MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
0.0 0.2 GO:0071253 connexin binding(GO:0071253)
0.0 0.1 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 1.0 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.2 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.4 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.2 GO:0070739 protein-glutamic acid ligase activity(GO:0070739)
0.0 0.2 GO:0042166 acetylcholine-gated cation channel activity(GO:0022848) acetylcholine binding(GO:0042166)
0.0 0.3 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 1.3 GO:0035591 signaling adaptor activity(GO:0035591)
0.0 0.6 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.8 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.4 GO:0071837 HMG box domain binding(GO:0071837)
0.0 19.2 GO:0032403 protein complex binding(GO:0032403)
0.0 0.2 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.7 GO:0098531 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 0.1 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 1.4 GO:0008201 heparin binding(GO:0008201)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 6.1 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 4.2 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 1.8 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 2.1 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 1.8 PID IL1 PATHWAY IL1-mediated signaling events
0.0 1.1 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 1.1 PID AURORA A PATHWAY Aurora A signaling
0.0 1.6 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.3 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.5 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 1.1 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.5 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.8 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.7 PID CDC42 PATHWAY CDC42 signaling events
0.0 0.8 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.6 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 2.5 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 3.2 NABA SECRETED FACTORS Genes encoding secreted soluble factors

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 13.8 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.2 3.3 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.2 2.8 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.1 2.0 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 0.7 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 0.3 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.1 1.0 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.1 0.7 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.1 0.5 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.1 1.0 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.8 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.7 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 1.0 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 1.4 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 1.8 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.5 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 1.0 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.2 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.9 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 1.3 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.6 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.2 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 1.1 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.2 REACTOME OPSINS Genes involved in Opsins
0.0 0.3 REACTOME SIGNALING BY NOTCH2 Genes involved in Signaling by NOTCH2
0.0 0.4 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.3 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.6 REACTOME CELL CELL JUNCTION ORGANIZATION Genes involved in Cell-cell junction organization
0.0 0.6 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.3 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.1 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.1 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.2 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.3 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions