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12D miR HR13_24

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Results for Tlx2

Z-value: 0.95

Motif logo

Transcription factors associated with Tlx2

Gene Symbol Gene ID Gene Info
ENSMUSG00000068327.3 T cell leukemia, homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Tlx2mm10_v2_chr6_-_83070225_83070377-0.244.8e-01Click!

Activity profile of Tlx2 motif

Sorted Z-values of Tlx2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_129121699 1.17 ENSMUST00000135763.1
ENSMUST00000149763.1
ENSMUST00000164649.1
hippocalcin
chr19_-_34255325 1.06 ENSMUST00000039631.8
actin, alpha 2, smooth muscle, aorta
chr4_-_141846359 0.82 ENSMUST00000037059.10
chymotrypsin C (caldecrin)
chr10_+_4710119 0.79 ENSMUST00000105588.1
ENSMUST00000105589.1
estrogen receptor 1 (alpha)
chr4_+_138775735 0.78 ENSMUST00000030528.2
phospholipase A2, group IID
chr14_+_115042752 0.76 ENSMUST00000134140.2
Mir17 host gene 1 (non-protein coding)
chr4_-_141846277 0.73 ENSMUST00000105781.1
chymotrypsin C (caldecrin)
chr9_-_21037775 0.70 ENSMUST00000180870.1
predicted gene, 26592
chr1_+_134962553 0.70 ENSMUST00000027687.7
ubiquitin-conjugating enzyme E2T (putative)
chr18_-_34720269 0.66 ENSMUST00000025224.7
glial cell line derived neurotrophic factor family receptor alpha 3
chr6_+_58596584 0.63 ENSMUST00000031822.6
ATP-binding cassette, sub-family G (WHITE), member 2
chr3_-_59130610 0.60 ENSMUST00000065220.6
ENSMUST00000091112.4
purinergic receptor P2Y, G-protein coupled, 14
chr2_+_163506808 0.59 ENSMUST00000143911.1
hepatic nuclear factor 4, alpha
chr11_+_3332426 0.57 ENSMUST00000136474.1
phosphoinositide-3-kinase interacting protein 1
chr5_+_45669907 0.57 ENSMUST00000117396.1
non-SMC condensin I complex, subunit G
chr14_+_13453937 0.57 ENSMUST00000153954.1
synaptoporin
chr10_-_67912620 0.57 ENSMUST00000064656.7
zinc finger protein 365
chr3_-_113574758 0.56 ENSMUST00000106540.1
amylase 1, salivary
chr7_+_24907618 0.56 ENSMUST00000151121.1
Rho guanine nucleotide exchange factor (GEF) 1
chr12_+_100779074 0.56 ENSMUST00000110073.1
ENSMUST00000110070.1
RIKEN cDNA 9030617O03 gene
chr4_-_99654983 0.55 ENSMUST00000136525.1
predicted gene 12688
chr9_-_103219823 0.54 ENSMUST00000168142.1
transferrin
chr5_-_137858034 0.52 ENSMUST00000110978.2
paired immunoglobin-like type 2 receptor beta 1
chr3_-_113574242 0.51 ENSMUST00000142505.2
amylase 1, salivary
chr19_-_11266122 0.50 ENSMUST00000169159.1
membrane-spanning 4-domains, subfamily A, member 1
chr16_-_17144415 0.50 ENSMUST00000115709.1
coiled-coil domain containing 116
chr8_-_105933832 0.50 ENSMUST00000034368.6
chymotrypsin-like
chr15_+_54745702 0.49 ENSMUST00000050027.8
nephroblastoma overexpressed gene
chr8_+_72761868 0.47 ENSMUST00000058099.8
coagulation factor II (thrombin) receptor-like 3
chr15_-_100687908 0.47 ENSMUST00000023775.7
chymotrypsin-like elastase family, member 1
chr2_-_121235689 0.47 ENSMUST00000142400.1
transformation related protein 53 binding protein 1
chr12_+_100779088 0.47 ENSMUST00000110069.1
RIKEN cDNA 9030617O03 gene
chr3_-_82074639 0.46 ENSMUST00000029635.8
guanylate cyclase 1, soluble, beta 3
chr14_+_66344369 0.45 ENSMUST00000118426.1
ENSMUST00000121955.1
ENSMUST00000120229.1
ENSMUST00000134440.1
stathmin-like 4
chrX_+_20549780 0.45 ENSMUST00000023832.6
regucalcin
chr4_-_128962420 0.44 ENSMUST00000119354.1
ENSMUST00000106068.1
ENSMUST00000030581.3
arginine decarboxylase
chr7_-_101921186 0.43 ENSMUST00000106965.1
ENSMUST00000106968.1
ENSMUST00000106967.1
leucine rich repeat containing 51
chr4_-_155774563 0.43 ENSMUST00000042196.3
von Willebrand factor A domain containing 1
chr1_-_45503282 0.41 ENSMUST00000086430.4
collagen, type V, alpha 2
chr12_+_41024329 0.41 ENSMUST00000134965.1
IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr7_-_46715676 0.41 ENSMUST00000006956.7
serum amyloid A 3
chr3_+_94413244 0.41 ENSMUST00000166032.1
ENSMUST00000045245.5
tudor and KH domain containing protein
chr2_+_38511643 0.40 ENSMUST00000054234.3
ENSMUST00000112902.1
ENSMUST00000112895.1
NIMA (never in mitosis gene a)-related expressed kinase 6
chr14_+_46760526 0.40 ENSMUST00000067426.4
cyclin-dependent kinase inhibitor 3
chr1_-_136960427 0.40 ENSMUST00000027649.7
nuclear receptor subfamily 5, group A, member 2
chr13_-_23430826 0.39 ENSMUST00000153753.1
ENSMUST00000141543.1
RIKEN cDNA C230035I16 gene
chr7_+_82648595 0.39 ENSMUST00000141726.1
ENSMUST00000179489.1
ENSMUST00000039881.3
elongation factor Tu GTP binding domain containing 1
chr6_+_122513583 0.38 ENSMUST00000032210.7
ENSMUST00000148517.1
microfibrillar associated protein 5
chr16_-_36666067 0.38 ENSMUST00000089620.4
CD86 antigen
chr2_-_117342831 0.37 ENSMUST00000178884.1
RAS guanyl releasing protein 1
chr17_-_31144271 0.37 ENSMUST00000024826.7
trefoil factor 2 (spasmolytic protein 1)
chr3_+_88043098 0.37 ENSMUST00000166021.1
ENSMUST00000029707.7
G patch domain containing 4
chr2_+_91922178 0.37 ENSMUST00000170432.1
cholinergic receptor, muscarinic 4
chr14_+_60768120 0.37 ENSMUST00000025940.6
C1q and tumor necrosis factor related protein 9
chr9_+_111439063 0.36 ENSMUST00000111879.3
doublecortin-like kinase 3
chr9_+_65398488 0.36 ENSMUST00000165682.1
ENSMUST00000085453.4
RAS-like, family 12
chr2_-_163397946 0.36 ENSMUST00000017961.4
ENSMUST00000109425.2
junctophilin 2
chr2_-_180954676 0.35 ENSMUST00000148905.1
ENSMUST00000103053.3
ENSMUST00000108873.2
Na+/K+ transporting ATPase interacting 4
chr4_+_130047840 0.35 ENSMUST00000044565.8
ENSMUST00000132251.1
collagen, type XVI, alpha 1
chr18_+_74065102 0.35 ENSMUST00000066583.1
predicted gene 9925
chr11_-_87108656 0.35 ENSMUST00000051395.8
proline rich 11
chr11_-_52282564 0.35 ENSMUST00000086844.3
transcription factor 7, T cell specific
chr10_-_128626464 0.35 ENSMUST00000026420.5
ribosomal protein S26
chr1_-_182409020 0.35 ENSMUST00000097444.1
predicted gene 10517
chr17_+_24632671 0.35 ENSMUST00000047611.2
nth (endonuclease III)-like 1 (E.coli)
chr13_-_21753851 0.34 ENSMUST00000074752.2
histone cluster 1, H2ak
chr2_+_3713449 0.34 ENSMUST00000027965.4
family with sequence similarity 107, member B
chr2_+_25054355 0.33 ENSMUST00000100334.4
ENSMUST00000152122.1
ENSMUST00000116574.3
ENSMUST00000006646.8
NMDA receptor synaptonuclear signaling and neuronal migration factor
chr2_+_25054396 0.33 ENSMUST00000102931.4
ENSMUST00000074422.7
ENSMUST00000132172.1
ENSMUST00000114388.1
ENSMUST00000114386.1
NMDA receptor synaptonuclear signaling and neuronal migration factor
chr4_+_135728116 0.33 ENSMUST00000102546.3
interleukin 22 receptor, alpha 1
chrX_+_100625737 0.33 ENSMUST00000048962.3
kinesin family member 4
chr2_-_117342949 0.33 ENSMUST00000102534.4
RAS guanyl releasing protein 1
chr9_+_109082485 0.32 ENSMUST00000026735.7
coiled-coil domain containing 51
chr6_+_78405148 0.32 ENSMUST00000023906.2
regenerating islet-derived 2
chr15_-_8710734 0.32 ENSMUST00000005493.7
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr6_-_119330723 0.32 ENSMUST00000068351.7
leucine-rich repeats and transmembrane domains 2
chr4_-_117929466 0.32 ENSMUST00000097913.2
artemin
chr8_-_111691002 0.31 ENSMUST00000034435.5
chymotrypsinogen B1
chr2_+_167062934 0.31 ENSMUST00000125674.1
RIKEN cDNA 1500012F01 gene
chr14_+_13454010 0.31 ENSMUST00000112656.2
synaptoporin
chr16_-_18413452 0.31 ENSMUST00000165430.1
ENSMUST00000147720.1
catechol-O-methyltransferase
chr3_-_32365643 0.31 ENSMUST00000029199.5
zinc finger matrin type 3
chr1_-_162898665 0.31 ENSMUST00000111510.1
ENSMUST00000045902.6
flavin containing monooxygenase 2
chr7_+_113766119 0.30 ENSMUST00000084696.4
spondin 1, (f-spondin) extracellular matrix protein
chr4_-_137766474 0.30 ENSMUST00000139951.1
alkaline phosphatase, liver/bone/kidney
chr6_-_119330668 0.30 ENSMUST00000112756.1
leucine-rich repeats and transmembrane domains 2
chr5_+_31251678 0.30 ENSMUST00000054829.7
ENSMUST00000114570.1
ENSMUST00000075611.7
keratinocyte associated protein 3
chr2_-_117342709 0.30 ENSMUST00000173541.1
ENSMUST00000172901.1
ENSMUST00000173252.1
RAS guanyl releasing protein 1
chr7_-_109438786 0.30 ENSMUST00000121748.1
serine/threonine kinase 33
chr16_+_35541275 0.29 ENSMUST00000120756.1
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B
chr3_-_32985076 0.29 ENSMUST00000108221.1
peroxisomal biogenesis factor 5-like
chr9_+_44107268 0.29 ENSMUST00000114821.2
ENSMUST00000114818.2
C1q and tumor necrosis factor related protein 5
chr3_-_32365608 0.29 ENSMUST00000168566.1
zinc finger matrin type 3
chr7_-_30924169 0.29 ENSMUST00000074671.6
hepcidin antimicrobial peptide 2
chr6_+_117168535 0.29 ENSMUST00000112866.1
ENSMUST00000112871.1
ENSMUST00000073043.4
chemokine (C-X-C motif) ligand 12
chr5_-_23783700 0.29 ENSMUST00000119946.1
pseudouridylate synthase 7 homolog (S. cerevisiae)
chr2_-_150668198 0.28 ENSMUST00000028944.3
acyl-CoA synthetase short-chain family member 1
chr7_-_116334132 0.28 ENSMUST00000170953.1
ribosomal protein S13
chr2_+_176431829 0.28 ENSMUST00000172025.1
predicted gene 14435
chr6_+_50110186 0.28 ENSMUST00000166318.1
ENSMUST00000036236.8
ENSMUST00000036225.8
membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
chr3_+_32365775 0.27 ENSMUST00000057768.2
RIKEN cDNA 4930429B21 gene
chr6_-_124636085 0.27 ENSMUST00000068797.2
predicted gene 5077
chr12_+_98268626 0.27 ENSMUST00000075072.4
G-protein coupled receptor 65
chr9_+_44107286 0.27 ENSMUST00000152956.1
ENSMUST00000114815.1
C1q and tumor necrosis factor related protein 5
chr4_-_41517326 0.27 ENSMUST00000030152.6
ENSMUST00000095126.4
RIKEN cDNA 1110017D15 gene
chr3_-_69004475 0.27 ENSMUST00000154741.1
ENSMUST00000148031.1
intraflagellar transport 80
chr7_-_126160992 0.26 ENSMUST00000164741.1
exportin 6
chr13_-_36734450 0.26 ENSMUST00000037623.8
neuritin 1
chr6_+_134981998 0.26 ENSMUST00000167323.1
apolipoprotein L domain containing 1
chr9_+_78113275 0.26 ENSMUST00000009972.5
ENSMUST00000117330.1
ENSMUST00000044551.7
intestinal cell kinase
chr4_+_130360132 0.26 ENSMUST00000105994.3
small nuclear ribonucleoprotein 40 (U5)
chr7_-_134225088 0.26 ENSMUST00000067680.4
a disintegrin and metallopeptidase domain 12 (meltrin alpha)
chr11_+_16257706 0.25 ENSMUST00000109645.2
ENSMUST00000109647.2
V-set and transmembrane domain containing 2A
chr7_-_132852606 0.25 ENSMUST00000120425.1
methyltransferase like 10
chr18_-_74064899 0.25 ENSMUST00000159162.1
ENSMUST00000091851.3
mitogen-activated protein kinase 4
chr6_-_115808736 0.25 ENSMUST00000081840.3
ribosomal protein L32
chr19_+_56287943 0.25 ENSMUST00000166049.1
hyaluronic acid binding protein 2
chr8_+_70594466 0.25 ENSMUST00000019283.9
myo-inositol 1-phosphate synthase A1
chr1_+_132298606 0.25 ENSMUST00000046071.4
kelch domain containing 8A
chr1_-_91413163 0.25 ENSMUST00000086851.1
hairy and enhancer of split 6
chr12_+_41024090 0.25 ENSMUST00000132121.1
IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr15_-_99457742 0.24 ENSMUST00000023747.7
NCK-associated protein 5-like
chr14_-_47394253 0.24 ENSMUST00000177822.1
discs, large (Drosophila) homolog-associated protein 5
chr1_+_134405984 0.24 ENSMUST00000173908.1
cytochrome b5 reductase 1
chr9_-_123678782 0.24 ENSMUST00000170591.1
ENSMUST00000171647.1
solute carrier family 6 (neurotransmitter transporter), member 20A
chr18_+_22345089 0.24 ENSMUST00000120223.1
ENSMUST00000097655.3
additional sex combs like 3 (Drosophila)
chr14_+_66344296 0.24 ENSMUST00000152093.1
ENSMUST00000074523.6
stathmin-like 4
chr4_+_141213948 0.24 ENSMUST00000097813.2
REM2 and RAB-like small GTPase 1
chr19_-_60874526 0.24 ENSMUST00000025961.6
peroxiredoxin 3
chr6_+_135065651 0.24 ENSMUST00000050104.7
G protein-coupled receptor, family C, group 5, member A
chr7_-_24545994 0.24 ENSMUST00000011776.6
phospholipase A2 inhibitor and LY6/PLAUR domain containing
chr7_+_39449479 0.24 ENSMUST00000061201.8
zinc finger protein 939
chr5_-_62766153 0.24 ENSMUST00000076623.4
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr5_+_143933059 0.23 ENSMUST00000166847.1
radial spoke head 10 homolog B (Chlamydomonas)
chr11_+_106751226 0.23 ENSMUST00000147326.2
ENSMUST00000182896.1
ENSMUST00000182908.1
ENSMUST00000086353.4
mast cell immunoglobulin like receptor 1
chr18_-_61786636 0.23 ENSMUST00000120472.1
actin filament associated protein 1-like 1
chr7_-_109439076 0.23 ENSMUST00000106745.2
ENSMUST00000090414.4
serine/threonine kinase 33
chr8_+_104101625 0.23 ENSMUST00000034339.8
cadherin 5
chr9_-_71771535 0.23 ENSMUST00000122065.1
ENSMUST00000121322.1
ENSMUST00000072899.2
cingulin-like 1
chr4_-_136053343 0.23 ENSMUST00000102536.4
ribosomal protein L11
chr3_+_69004969 0.23 ENSMUST00000136502.1
ENSMUST00000107803.1
structural maintenance of chromosomes 4
chr5_+_107900859 0.22 ENSMUST00000153590.1
ribosomal protein L5
chr7_+_28437447 0.22 ENSMUST00000108292.2
ENSMUST00000108289.1
glia maturation factor, gamma
chr15_+_35296090 0.22 ENSMUST00000022952.4
odd-skipped related 2
chr3_+_69004711 0.22 ENSMUST00000042901.8
structural maintenance of chromosomes 4
chr15_+_93398344 0.22 ENSMUST00000109256.3
ENSMUST00000068457.7
ENSMUST00000049122.8
ENSMUST00000165935.1
periphilin 1
chr17_+_35194502 0.22 ENSMUST00000173600.1
lymphotoxin B
chr10_+_79988584 0.22 ENSMUST00000004784.4
ENSMUST00000105374.1
calponin 2
chr15_+_77729091 0.22 ENSMUST00000109775.2
apolipoprotein L 9b
chr17_+_35439155 0.22 ENSMUST00000071951.6
ENSMUST00000078205.7
ENSMUST00000116598.3
ENSMUST00000076256.7
histocompatibility 2, Q region locus 7
chrX_-_48674478 0.21 ENSMUST00000053970.3
G-protein coupled receptor 119
chr9_-_109059216 0.21 ENSMUST00000112053.1
three prime repair exonuclease 1
chr2_+_107290590 0.21 ENSMUST00000037012.2
potassium voltage-gated channel, shaker-related subfamily, member 4
chr9_-_88522876 0.21 ENSMUST00000180563.2
ENSMUST00000183030.1
ENSMUST00000182232.1
small nucleolar RNA host gene 5
chr3_-_145649970 0.21 ENSMUST00000029846.3
cysteine rich protein 61
chr3_+_88615367 0.21 ENSMUST00000176539.1
rho/rac guanine nucleotide exchange factor (GEF) 2
chr11_-_78984831 0.21 ENSMUST00000073001.4
ENSMUST00000108269.3
lectin, galactose binding, soluble 9
chr3_-_154597045 0.21 ENSMUST00000052774.1
ENSMUST00000170461.1
ENSMUST00000122976.1
tRNA-yW synthesizing protein 3 homolog (S. cerevisiae)
chr15_-_103340085 0.21 ENSMUST00000168828.1
zinc finger protein 385A
chr11_+_43474276 0.20 ENSMUST00000173002.1
ENSMUST00000057679.3
C1q and tumor necrosis factor related protein 2
chr13_-_92483996 0.20 ENSMUST00000040106.7
family with sequence similarity 151, member B
chr11_-_78984946 0.20 ENSMUST00000108268.3
lectin, galactose binding, soluble 9
chr9_+_124121534 0.20 ENSMUST00000111442.1
ENSMUST00000171499.2
chemokine (C-C motif) receptor 5
chr11_+_115899943 0.20 ENSMUST00000152171.1
small integral membrane protein 5
chr18_+_75000469 0.20 ENSMUST00000079716.5
ribosomal protein L17
chr14_-_46822232 0.20 ENSMUST00000111817.1
ENSMUST00000079314.5
glia maturation factor, beta
chr2_-_6130117 0.20 ENSMUST00000126551.1
ENSMUST00000054254.5
ENSMUST00000114942.2
proline and serine rich 2
chr2_+_84826997 0.20 ENSMUST00000028470.3
translocase of inner mitochondrial membrane 10
chr11_-_51650813 0.20 ENSMUST00000142721.1
ENSMUST00000156835.1
ENSMUST00000001080.9
NEDD4 binding protein 3
chr7_-_4778141 0.20 ENSMUST00000094892.5
interleukin 11
chr18_+_60376029 0.20 ENSMUST00000066912.5
ENSMUST00000032473.6
interferon inducible GTPase 1
chr14_+_66911170 0.20 ENSMUST00000089236.3
ENSMUST00000122431.2
paraneoplastic antigen MA2
chr2_+_10153563 0.20 ENSMUST00000026886.7
inter-alpha (globulin) inhibitor H5
chr11_-_101987004 0.19 ENSMUST00000107173.2
ENSMUST00000107172.1
dual specificity phosphatase 3 (vaccinia virus phosphatase VH1-related)
chr11_+_78178651 0.19 ENSMUST00000092880.7
ENSMUST00000127587.1
ENSMUST00000108338.1
TLC domain containing 1
chr6_+_50110837 0.19 ENSMUST00000167628.1
membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
chr9_-_121839460 0.19 ENSMUST00000135986.2
coiled-coil domain containing 13
chr11_+_101442298 0.19 ENSMUST00000077856.6
ribosomal protein L27
chr2_+_50066429 0.19 ENSMUST00000112712.3
ENSMUST00000128451.1
ENSMUST00000053208.7
LY6/PLAUR domain containing 6
chr11_+_83437678 0.19 ENSMUST00000037378.4
RIKEN cDNA 1700020L24 gene
chr12_+_102283116 0.19 ENSMUST00000101114.4
ENSMUST00000150795.1
Ras and Rab interactor 3
chr3_-_88772578 0.19 ENSMUST00000090945.4
synaptotagmin XI
chr16_-_56886131 0.19 ENSMUST00000023435.5
transmembrane protein 45a
chr10_+_40883819 0.19 ENSMUST00000105509.1
WAS protein family, member 1
chr5_+_107900502 0.18 ENSMUST00000082223.6
ribosomal protein L5
chr14_-_61360395 0.18 ENSMUST00000022494.8
emopamil binding protein-like
chrX_+_73892102 0.18 ENSMUST00000033765.7
ENSMUST00000101470.2
ENSMUST00000114395.1
arginine vasopressin receptor 2
chr5_+_65107551 0.18 ENSMUST00000101192.2
kelch-like 5
chr8_-_126971062 0.18 ENSMUST00000045994.6
RNA binding motif protein 34
chr19_-_5924797 0.18 ENSMUST00000055458.4
CDC42 effector protein (Rho GTPase binding) 2
chr19_-_46044914 0.18 ENSMUST00000026252.7
LIM domain binding 1
chr13_+_4233730 0.18 ENSMUST00000081326.6
aldo-keto reductase family 1, member C19
chr7_+_109519139 0.18 ENSMUST00000143107.1
ribosomal protein L27A
chr2_+_103073669 0.18 ENSMUST00000011055.6
APAF1 interacting protein
chr3_-_151749877 0.18 ENSMUST00000029671.7
interferon-induced protein 44
chr10_-_128919259 0.18 ENSMUST00000149961.1
ENSMUST00000026406.7
retinol dehydrogenase 5
chr6_+_108660772 0.18 ENSMUST00000163617.1
basic helix-loop-helix family, member e40
chr4_+_57845240 0.18 ENSMUST00000102903.1
ENSMUST00000107598.3
A kinase (PRKA) anchor protein 2
chr1_-_44101982 0.18 ENSMUST00000127923.1
testis expressed 30
chr14_+_32028989 0.17 ENSMUST00000022460.4
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 15

Network of associatons between targets according to the STRING database.

First level regulatory network of Tlx2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0031283 negative regulation of cGMP metabolic process(GO:0030824) negative regulation of cGMP biosynthetic process(GO:0030827) negative regulation of guanylate cyclase activity(GO:0031283)
0.2 0.7 GO:0061300 cerebellum vasculature development(GO:0061300)
0.2 0.9 GO:1903630 regulation of aminoacyl-tRNA ligase activity(GO:1903630)
0.2 0.6 GO:0019389 glucuronoside metabolic process(GO:0019389)
0.2 0.6 GO:0010534 regulation of activation of JAK2 kinase activity(GO:0010534) activation of JAK2 kinase activity(GO:0042977) negative regulation of activation of JAK2 kinase activity(GO:1902569)
0.2 0.6 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.2 0.6 GO:0033566 gamma-tubulin complex localization(GO:0033566)
0.2 0.7 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
0.2 0.7 GO:0099527 postsynapse to nucleus signaling pathway(GO:0099527)
0.2 0.8 GO:0060523 prostate epithelial cord elongation(GO:0060523)
0.2 0.5 GO:0099543 trans-synaptic signaling by soluble gas(GO:0099543)
0.2 0.6 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.1 1.2 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.1 0.9 GO:0061113 pancreas morphogenesis(GO:0061113)
0.1 0.4 GO:0002644 negative regulation of tolerance induction(GO:0002644)
0.1 0.3 GO:0006285 base-excision repair, AP site formation(GO:0006285) nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.1 0.3 GO:0097021 lymphocyte migration into lymphoid organs(GO:0097021)
0.1 0.4 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 0.3 GO:0031335 regulation of sulfur amino acid metabolic process(GO:0031335)
0.1 0.4 GO:0035524 proline transmembrane transport(GO:0035524)
0.1 0.3 GO:0070343 white fat cell proliferation(GO:0070343) regulation of white fat cell proliferation(GO:0070350)
0.1 1.0 GO:0033089 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.1 0.4 GO:2000562 regulation of natural killer cell degranulation(GO:0043321) negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.1 0.2 GO:2000537 regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.1 0.6 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.1 0.8 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.1 0.5 GO:0070447 positive regulation of oligodendrocyte progenitor proliferation(GO:0070447)
0.1 0.2 GO:2000434 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.1 0.2 GO:0071846 actin filament debranching(GO:0071846)
0.1 0.3 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.1 0.4 GO:0007207 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.1 0.4 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.1 0.3 GO:0034757 negative regulation of iron ion transport(GO:0034757) negative regulation of iron ion transmembrane transport(GO:0034760)
0.1 0.3 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.1 0.1 GO:1902567 negative regulation of eosinophil activation(GO:1902567)
0.1 0.2 GO:0090172 microtubule cytoskeleton organization involved in homologous chromosome segregation(GO:0090172)
0.1 0.2 GO:1902162 regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162)
0.1 1.0 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.1 0.3 GO:0036518 chemorepulsion of dopaminergic neuron axon(GO:0036518)
0.1 0.3 GO:0043973 histone H3-K4 acetylation(GO:0043973)
0.1 0.2 GO:1990927 negative regulation of membrane invagination(GO:1905154) calcium ion regulated lysosome exocytosis(GO:1990927)
0.1 0.2 GO:0036023 limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023)
0.1 0.3 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.1 0.3 GO:0072592 oxygen metabolic process(GO:0072592)
0.0 0.2 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.0 0.3 GO:0006083 acetate metabolic process(GO:0006083) short-chain fatty acid biosynthetic process(GO:0051790)
0.0 0.2 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.0 0.2 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.1 GO:0043382 positive regulation of memory T cell differentiation(GO:0043382) regulation of T-helper 17 cell lineage commitment(GO:2000328)
0.0 0.3 GO:0002568 somatic diversification of T cell receptor genes(GO:0002568) somatic recombination of T cell receptor gene segments(GO:0002681) T cell receptor V(D)J recombination(GO:0033153)
0.0 0.2 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.0 0.2 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.1 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.0 0.3 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.0 0.1 GO:2000017 positive regulation of determination of dorsal identity(GO:2000017)
0.0 0.3 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
0.0 0.3 GO:0003278 apoptotic process involved in heart morphogenesis(GO:0003278)
0.0 0.1 GO:0006566 threonine metabolic process(GO:0006566)
0.0 0.1 GO:0007521 muscle cell fate determination(GO:0007521)
0.0 0.1 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.0 0.2 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.0 0.1 GO:0010986 positive regulation of lipoprotein particle clearance(GO:0010986)
0.0 0.1 GO:0002587 negative regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002587)
0.0 0.1 GO:2001160 regulation of histone H3-K79 methylation(GO:2001160)
0.0 0.2 GO:1901552 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.0 0.1 GO:0070844 misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846)
0.0 0.3 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.0 0.8 GO:0048485 sympathetic nervous system development(GO:0048485)
0.0 0.2 GO:0045905 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0 0.1 GO:0015786 UDP-glucose transport(GO:0015786)
0.0 0.5 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.1 GO:0045112 integrin biosynthetic process(GO:0045112) regulation of integrin biosynthetic process(GO:0045113)
0.0 0.5 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.0 0.1 GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.0 0.3 GO:0061727 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0 0.2 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.0 0.1 GO:0002414 immunoglobulin transcytosis in epithelial cells(GO:0002414)
0.0 0.2 GO:0031622 positive regulation of fever generation(GO:0031622) negative regulation of macrophage apoptotic process(GO:2000110)
0.0 0.1 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.0 0.0 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.0 0.1 GO:0045409 negative regulation of interleukin-6 biosynthetic process(GO:0045409)
0.0 0.5 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.0 0.1 GO:0051121 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.2 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.0 0.2 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.0 0.2 GO:0061091 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.0 0.4 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.1 GO:0032489 regulation of Cdc42 protein signal transduction(GO:0032489)
0.0 0.1 GO:2000383 regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
0.0 0.1 GO:0090365 regulation of mRNA modification(GO:0090365)
0.0 0.2 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0 0.2 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.4 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.1 GO:0098961 dendritic transport of ribonucleoprotein complex(GO:0098961) dendritic transport of messenger ribonucleoprotein complex(GO:0098963) anterograde dendritic transport of messenger ribonucleoprotein complex(GO:0098964)
0.0 0.1 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
0.0 0.1 GO:0035521 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.0 0.1 GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987)
0.0 0.2 GO:0033004 negative regulation of mast cell activation(GO:0033004)
0.0 0.2 GO:0098953 receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628)
0.0 0.1 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0 0.1 GO:0001830 trophectodermal cell fate commitment(GO:0001830)
0.0 0.1 GO:0045345 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343) positive regulation of MHC class I biosynthetic process(GO:0045345)
0.0 0.2 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.8 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 0.1 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.0 0.3 GO:0001967 suckling behavior(GO:0001967)
0.0 0.1 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.0 0.3 GO:0001522 pseudouridine synthesis(GO:0001522)
0.0 0.1 GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.0 0.2 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.1 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.0 0.4 GO:0009648 photoperiodism(GO:0009648)
0.0 0.3 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.1 GO:1903874 ferrous iron transmembrane transport(GO:1903874)
0.0 0.1 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 0.3 GO:0033622 integrin activation(GO:0033622)
0.0 0.1 GO:0010593 negative regulation of lamellipodium assembly(GO:0010593)
0.0 0.1 GO:0015862 uridine transport(GO:0015862)
0.0 0.1 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.6 GO:0033119 negative regulation of RNA splicing(GO:0033119)
0.0 0.1 GO:0050917 sensory perception of umami taste(GO:0050917)
0.0 0.0 GO:0006086 acetyl-CoA biosynthetic process from pyruvate(GO:0006086) regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.0 0.1 GO:0006071 glycerol metabolic process(GO:0006071)
0.0 0.2 GO:0050765 negative regulation of phagocytosis(GO:0050765)
0.0 0.1 GO:0019896 axonal transport of mitochondrion(GO:0019896)
0.0 0.1 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.0 0.1 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.0 GO:0032227 negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.0 0.4 GO:0035458 cellular response to interferon-beta(GO:0035458)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.2 1.1 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.1 0.4 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.8 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.1 1.0 GO:0000796 condensin complex(GO:0000796)
0.1 1.2 GO:0044327 dendritic spine head(GO:0044327)
0.1 0.4 GO:0071547 piP-body(GO:0071547)
0.1 0.5 GO:0097433 dense body(GO:0097433)
0.0 0.4 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.3 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.0 0.2 GO:0071942 XPC complex(GO:0071942)
0.0 0.2 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.9 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.2 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.0 0.1 GO:0055087 Ski complex(GO:0055087)
0.0 0.6 GO:0032279 asymmetric synapse(GO:0032279)
0.0 2.0 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.3 GO:0002177 manchette(GO:0002177)
0.0 0.2 GO:0042629 mast cell granule(GO:0042629)
0.0 0.5 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.0 0.1 GO:0005827 polar microtubule(GO:0005827)
0.0 0.2 GO:0005638 lamin filament(GO:0005638)
0.0 0.1 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.0 0.1 GO:0098651 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.0 1.0 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.6 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.3 GO:0097542 ciliary tip(GO:0097542)
0.0 0.3 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.5 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.2 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.5 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.2 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.1 GO:0070652 HAUS complex(GO:0070652)
0.0 0.3 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.4 GO:0005682 U5 snRNP(GO:0005682)
0.0 0.1 GO:0097255 R2TP complex(GO:0097255)
0.0 0.2 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.1 GO:0097447 dendritic tree(GO:0097447)
0.0 0.2 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.4 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.2 GO:0031209 SCAR complex(GO:0031209)
0.0 0.1 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.7 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.1 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.0 0.1 GO:1990393 3M complex(GO:1990393)
0.0 0.2 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.1 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.1 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.2 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.5 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.1 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 1.0 GO:0005581 collagen trimer(GO:0005581)
0.0 0.5 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.1 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 0.1 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.1 GO:0000243 commitment complex(GO:0000243)
0.0 0.1 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0038052 type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.2 0.6 GO:0070540 stearic acid binding(GO:0070540)
0.2 1.1 GO:0004556 alpha-amylase activity(GO:0004556)
0.1 0.5 GO:0015057 thrombin receptor activity(GO:0015057)
0.1 0.3 GO:0042015 interleukin-20 binding(GO:0042015)
0.1 0.3 GO:0030116 glial cell-derived neurotrophic factor receptor binding(GO:0030116)
0.1 0.3 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.1 1.0 GO:0019992 diacylglycerol binding(GO:0019992)
0.1 0.3 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.1 0.6 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.1 0.3 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.1 0.5 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.1 0.5 GO:0072510 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.1 0.4 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.1 0.6 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.1 0.3 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.1 0.3 GO:0000702 oxidized base lesion DNA N-glycosylase activity(GO:0000702)
0.1 0.4 GO:0016936 galactoside binding(GO:0016936)
0.1 0.5 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 0.7 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.3 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.3 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 0.1 GO:0051765 inositol tetrakisphosphate kinase activity(GO:0051765)
0.0 0.1 GO:0035717 chemokine (C-C motif) ligand 7 binding(GO:0035717)
0.0 0.6 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.3 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.2 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 0.3 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 0.2 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.0 0.1 GO:0016964 alpha-2 macroglobulin receptor activity(GO:0016964)
0.0 0.2 GO:0016728 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.4 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.0 0.2 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.0 0.1 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.0 0.4 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.5 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.3 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0 0.3 GO:0043426 MRF binding(GO:0043426)
0.0 0.4 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.1 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
0.0 0.3 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.2 GO:0004920 interleukin-10 receptor activity(GO:0004920)
0.0 0.2 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.1 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.6 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.0 0.8 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.2 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.2 GO:0031812 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.0 0.2 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.2 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.2 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.1 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.0 0.4 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.2 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.2 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 0.1 GO:0034190 apolipoprotein receptor binding(GO:0034190)
0.0 0.2 GO:1990446 U1 snRNP binding(GO:1990446)
0.0 0.2 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.4 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.3 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.3 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.2 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 0.1 GO:0019237 centromeric DNA binding(GO:0019237)
0.0 0.3 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.1 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.0 0.1 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.0 0.1 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.1 GO:0034603 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.0 0.0 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.1 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.0 0.3 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.7 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.1 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.4 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.2 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.0 0.5 GO:0005112 Notch binding(GO:0005112)
0.0 0.1 GO:0043758 acetate-CoA ligase (ADP-forming) activity(GO:0043758)
0.0 0.1 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.0 0.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.1 GO:0031705 bombesin receptor binding(GO:0031705)
0.0 0.1 GO:0051022 Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0 0.1 GO:0035473 lipase binding(GO:0035473)
0.0 0.0 GO:0016979 lipoate-protein ligase activity(GO:0016979)
0.0 0.1 GO:0050694 galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.0 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.2 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.2 GO:0033549 MAP kinase phosphatase activity(GO:0033549)
0.0 0.1 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.4 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 1.1 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.9 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.9 PID AURORA B PATHWAY Aurora B signaling
0.0 0.9 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 1.0 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.3 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 0.7 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.7 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.4 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.1 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.8 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 0.4 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.1 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.3 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.3 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.6 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.6 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.5 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.7 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.0 0.3 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.9 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.6 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 2.6 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 1.0 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.1 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.2 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.9 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 0.2 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.3 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.9 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.6 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.1 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.2 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0 0.3 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.3 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.3 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.1 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.1 REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS Genes involved in NRIF signals cell death from the nucleus
0.0 0.1 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs