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12D miR HR13_24

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Results for Ddit3

Z-value: 1.59

Motif logo

Transcription factors associated with Ddit3

Gene Symbol Gene ID Gene Info
ENSMUSG00000025408.9 DNA-damage inducible transcript 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Ddit3mm10_v2_chr10_+_127290774_1272908030.567.4e-02Click!

Activity profile of Ddit3 motif

Sorted Z-values of Ddit3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_45060036 3.35 ENSMUST00000114641.1
contactin associated protein-like 2
chr2_+_119351222 2.99 ENSMUST00000028780.3
ChaC, cation transport regulator 1
chr8_+_106603351 2.59 ENSMUST00000000312.5
ENSMUST00000167688.1
cadherin 1
chr7_+_121083322 2.44 ENSMUST00000047025.8
ENSMUST00000170106.1
otoancorin
chr7_+_18884679 2.41 ENSMUST00000032573.6
peptidoglycan recognition protein 1
chr7_-_79793788 2.31 ENSMUST00000032760.5
mesoderm posterior 1
chr5_+_137288273 2.17 ENSMUST00000024099.4
ENSMUST00000085934.3
acetylcholinesterase
chrX_+_52791179 2.05 ENSMUST00000101588.1
coiled-coil domain containing 160
chr14_+_66868850 2.02 ENSMUST00000100453.1
predicted gene 5464
chr15_-_32244632 1.93 ENSMUST00000181536.1
RIKEN cDNA 0610007N19
chr10_+_112271123 1.89 ENSMUST00000092175.2
potassium voltage gated channel, Shaw-related subfamily, member 2
chr2_-_152344009 1.66 ENSMUST00000040312.6
tribbles homolog 3 (Drosophila)
chr10_+_5639210 1.52 ENSMUST00000019906.4
vasoactive intestinal polypeptide
chr10_-_109823585 1.48 ENSMUST00000161582.1
neuron navigator 3
chr5_-_131538687 1.46 ENSMUST00000161374.1
autism susceptibility candidate 2
chr4_-_117133953 1.46 ENSMUST00000076859.5
polo-like kinase 3
chr3_-_58525867 1.45 ENSMUST00000029385.7
stress-associated endoplasmic reticulum protein 1
chr14_-_66868572 1.43 ENSMUST00000022629.8
dihydropyrimidinase-like 2
chr1_-_127677923 1.41 ENSMUST00000160616.1
transmembrane protein 163
chr11_-_5152218 1.37 ENSMUST00000163299.1
ENSMUST00000062821.6
EMI domain containing 1
chrX_-_162565514 1.35 ENSMUST00000154424.1
RALBP1 associated Eps domain containing protein 2
chr10_+_13501001 1.33 ENSMUST00000060212.6
ENSMUST00000121465.2
fucosidase, alpha-L- 2, plasma
chr14_+_65971164 1.27 ENSMUST00000144619.1
clusterin
chr9_-_95845215 1.14 ENSMUST00000093800.2
plastin 1 (I-isoform)
chr3_+_108186332 1.12 ENSMUST00000050909.6
ENSMUST00000106659.2
ENSMUST00000106656.1
ENSMUST00000106661.2
adhesion molecule with Ig like domain 1
chr1_-_5019342 1.12 ENSMUST00000002533.8
regulator of G-protein signaling 20
chr13_+_42680565 1.12 ENSMUST00000128646.1
phosphatase and actin regulator 1
chr3_-_97297778 1.12 ENSMUST00000181368.1
predicted gene, 17608
chr1_+_174501796 1.10 ENSMUST00000030039.7
formin 2
chr7_-_120982260 1.09 ENSMUST00000033169.8
cerebellar degeneration-related 2
chr16_+_36041184 1.04 ENSMUST00000042203.8
WD repeat domain 5B
chr1_+_188263034 1.04 ENSMUST00000060479.7
Usher syndrome 2A (autosomal recessive, mild)
chr16_+_78301458 0.99 ENSMUST00000023572.7
coxsackie virus and adenovirus receptor
chr18_+_37421418 0.99 ENSMUST00000053073.4
protocadherin beta 11
chr1_-_126492900 0.98 ENSMUST00000161954.1
NCK-associated protein 5
chr14_+_65970804 0.98 ENSMUST00000138191.1
clusterin
chr18_+_38993126 0.97 ENSMUST00000097593.2
Rho GTPase activating protein 26
chr11_-_120643643 0.94 ENSMUST00000141254.1
ENSMUST00000170556.1
ENSMUST00000151876.1
ENSMUST00000026133.8
ENSMUST00000139706.1
pyrroline-5-carboxylate reductase 1
chr11_+_110399115 0.94 ENSMUST00000020949.5
ENSMUST00000100260.1
mitogen-activated protein kinase kinase 6
chrX_+_103422010 0.94 ENSMUST00000182089.1
predicted gene, 26992
chr16_+_24721842 0.93 ENSMUST00000115314.2
LIM domain containing preferred translocation partner in lipoma
chr11_+_71750980 0.93 ENSMUST00000108511.1
WSC domain containing 1
chr14_+_65971049 0.91 ENSMUST00000128539.1
clusterin
chr7_+_107370728 0.90 ENSMUST00000137663.1
ENSMUST00000073459.5
synaptotagmin IX
chr19_-_59076069 0.90 ENSMUST00000047511.7
ENSMUST00000163821.1
RIKEN cDNA 4930506M07 gene
chr1_+_157526127 0.90 ENSMUST00000111700.1
SEC16 homolog B (S. cerevisiae)
chr1_-_126492683 0.90 ENSMUST00000162877.1
NCK-associated protein 5
chr2_-_130839683 0.90 ENSMUST00000119422.1
RIKEN cDNA 4930402H24 gene
chr6_-_115592571 0.89 ENSMUST00000112957.1
RIKEN cDNA 2510049J12 gene
chr15_-_59082026 0.87 ENSMUST00000080371.6
metastasis suppressor 1
chrX_+_94724569 0.87 ENSMUST00000101388.2
zinc finger, X-linked, duplicated B
chr17_+_34417347 0.85 ENSMUST00000142317.1
cDNA sequence BC051142
chr8_-_22476809 0.82 ENSMUST00000163774.1
ENSMUST00000033935.8
small integral membrane protein 19
chr4_-_101844023 0.82 ENSMUST00000106919.1
RIKEN cDNA B020004J07 gene
chr8_+_25720054 0.82 ENSMUST00000068916.8
ENSMUST00000139836.1
phosphatidic acid phosphatase type 2 domain containing 1B
chr13_+_45965211 0.82 ENSMUST00000038032.3
RIKEN cDNA 5033430I15 gene
chr7_+_64287665 0.79 ENSMUST00000032736.4
myotubularin related protein 10
chr15_-_83510793 0.79 ENSMUST00000154401.1
tubulin tyrosine ligase-like 1
chr17_+_37270214 0.78 ENSMUST00000038580.6
histocompatibility 2, M region locus 3
chr4_-_56224520 0.78 ENSMUST00000128591.1
RIKEN cDNA 2310081O03 gene
chr7_+_135268579 0.77 ENSMUST00000097983.3
neuropeptide S
chr11_+_60728398 0.76 ENSMUST00000018743.4
mitochondrial elongation factor 2
chr19_+_47865543 0.75 ENSMUST00000120645.1
glutathione S-transferase omega 2
chr18_-_37644185 0.73 ENSMUST00000066272.4
TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr4_+_115057410 0.72 ENSMUST00000136946.1
T cell acute lymphocytic leukemia 1
chr3_-_108200415 0.71 ENSMUST00000106654.1
cytochrome b-561 domain containing 1
chr2_-_120850598 0.68 ENSMUST00000028740.4
tau tubulin kinase 2
chr5_-_120749848 0.67 ENSMUST00000053909.6
ENSMUST00000081491.6
2'-5' oligoadenylate synthetase 2
chr5_-_43981757 0.63 ENSMUST00000061299.7
fibroblast growth factor binding protein 1
chr6_-_138422898 0.62 ENSMUST00000161450.1
ENSMUST00000163024.1
ENSMUST00000162185.1
LIM domain only 3
chr12_+_105604091 0.61 ENSMUST00000041229.4
bradykinin receptor, beta 1
chr7_+_120982521 0.61 ENSMUST00000149535.1
ENSMUST00000138177.1
RIKEN cDNA 4933427G17 gene
chr2_+_23069210 0.61 ENSMUST00000155602.1
acyl-Coenzyme A binding domain containing 5
chr3_-_108200807 0.60 ENSMUST00000106655.1
ENSMUST00000065664.6
cytochrome b-561 domain containing 1
chr2_-_91194767 0.59 ENSMUST00000111355.1
nuclear receptor subfamily 1, group H, member 3
chr12_-_87102350 0.59 ENSMUST00000110176.1
neuroglobin
chr2_-_91195035 0.58 ENSMUST00000111356.1
nuclear receptor subfamily 1, group H, member 3
chr8_-_67818284 0.56 ENSMUST00000120071.1
pleckstrin and Sec7 domain containing 3
chr5_-_36695969 0.56 ENSMUST00000031091.9
ENSMUST00000140063.1
DNA segment, Chr 5, ERATO Doi 579, expressed
chr8_-_99416397 0.55 ENSMUST00000155527.1
ENSMUST00000142129.1
ENSMUST00000093249.4
ENSMUST00000142475.2
ENSMUST00000128860.1
cadherin 8
chr1_-_165460430 0.54 ENSMUST00000027856.7
DDB1 and CUL4 associated factor 6
chr11_-_115062177 0.54 ENSMUST00000062787.7
CD300e antigen
chr14_-_21052120 0.54 ENSMUST00000130370.1
ENSMUST00000022371.3
adaptor-related protein complex 3, mu 1 subunit
chr2_-_91195097 0.52 ENSMUST00000002177.2
ENSMUST00000111354.1
nuclear receptor subfamily 1, group H, member 3
chr5_-_113081579 0.52 ENSMUST00000131708.1
ENSMUST00000117143.1
ENSMUST00000119627.1
crystallin, beta B3
chr7_+_144896523 0.52 ENSMUST00000033389.5
fibroblast growth factor 15
chr14_+_59201209 0.51 ENSMUST00000173547.1
ENSMUST00000043227.6
ENSMUST00000022551.7
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
chr12_+_10390756 0.51 ENSMUST00000020947.5
retinol dehydrogenase 14 (all-trans and 9-cis)
chr11_-_95146263 0.50 ENSMUST00000021241.6
distal-less homeobox 4
chr1_-_39651165 0.50 ENSMUST00000053355.4
cellular repressor of E1A-stimulated genes 2
chr2_-_32961592 0.50 ENSMUST00000133832.1
ENSMUST00000124492.1
ENSMUST00000145578.1
ENSMUST00000127321.1
ENSMUST00000113200.1
leucine rich repeat and sterile alpha motif containing 1
chr5_-_74531619 0.49 ENSMUST00000113542.2
ENSMUST00000072857.6
ENSMUST00000121330.1
ENSMUST00000151474.1
Sec1 family domain containing 2
chr3_-_151835967 0.48 ENSMUST00000106126.1
prostaglandin F receptor
chr11_+_51763682 0.47 ENSMUST00000020653.5
SAR1 gene homolog B (S. cerevisiae)
chr6_+_88724667 0.45 ENSMUST00000163271.1
monoglyceride lipase
chr9_-_20644726 0.44 ENSMUST00000148631.1
ENSMUST00000131128.1
ENSMUST00000151861.1
ENSMUST00000131343.1
ENSMUST00000086458.3
F-box and leucine-rich repeat protein 12
chr13_+_24614608 0.44 ENSMUST00000091694.3
family with sequence similarity 65, member B
chr5_-_53707532 0.43 ENSMUST00000031093.3
cholecystokinin A receptor
chr7_-_46715676 0.43 ENSMUST00000006956.7
serum amyloid A 3
chr11_-_96075581 0.43 ENSMUST00000107686.1
ENSMUST00000107684.1
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c1 (subunit 9)
chr8_-_67818218 0.42 ENSMUST00000059374.4
pleckstrin and Sec7 domain containing 3
chr11_-_96075655 0.42 ENSMUST00000090541.5
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c1 (subunit 9)
chr6_+_125494419 0.42 ENSMUST00000181266.1
predicted gene, 26728
chr11_-_72550255 0.42 ENSMUST00000021154.6
spinster homolog 3
chr6_+_115675983 0.40 ENSMUST00000068960.9
RIKEN cDNA D830050J10 gene
chr10_+_127195240 0.40 ENSMUST00000181578.1
RIKEN cDNA F420014N23 gene
chr8_+_92961027 0.40 ENSMUST00000072939.6
solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
chr15_-_93595877 0.40 ENSMUST00000048982.4
prickle homolog 1 (Drosophila)
chr1_-_58586191 0.39 ENSMUST00000038372.7
ENSMUST00000097724.3
ENSMUST00000161000.1
ENSMUST00000161600.1
family with sequence similarity 126, member B
chr18_+_37333853 0.39 ENSMUST00000061717.2
protocadherin beta 6
chr8_+_105131800 0.37 ENSMUST00000161289.1
carboxylesterase 4A
chr6_+_88724828 0.34 ENSMUST00000089449.2
monoglyceride lipase
chr11_-_59571813 0.34 ENSMUST00000071943.2
olfactory receptor 222
chr3_-_30509462 0.33 ENSMUST00000173899.1
MDS1 and EVI1 complex locus
chrX_-_60147643 0.33 ENSMUST00000033478.4
ENSMUST00000101531.3
mcf.2 transforming sequence
chr5_-_43235352 0.33 ENSMUST00000140650.2
predicted gene 7854
chr7_-_75309262 0.33 ENSMUST00000165175.1
synaptic vesicle glycoprotein 2 b
chr1_-_195131536 0.33 ENSMUST00000075451.6
complement component (3b/4b) receptor 1-like
chr2_-_6935081 0.32 ENSMUST00000100426.2
predicted gene 10855
chrX_-_75163753 0.32 ENSMUST00000101433.2
small integral membrane protein 9
chr10_-_121626316 0.31 ENSMUST00000039810.7
exportin, tRNA (nuclear export receptor for tRNAs)
chr7_-_126082406 0.31 ENSMUST00000073935.5
GSG1-like
chr15_-_83510861 0.31 ENSMUST00000109479.1
ENSMUST00000109480.1
ENSMUST00000016897.4
tubulin tyrosine ligase-like 1
chr9_-_121495678 0.30 ENSMUST00000035120.4
cholecystokinin
chr6_-_34955903 0.29 ENSMUST00000147169.1
RIKEN cDNA 2010107G12 gene
chr3_-_153906138 0.28 ENSMUST00000005630.4
mutS homolog 4 (E. coli)
chr6_+_48895243 0.27 ENSMUST00000031835.7
amine oxidase, copper-containing 1
chr3_-_127408986 0.26 ENSMUST00000182588.1
ENSMUST00000182959.1
ENSMUST00000182452.1
ankyrin 2, brain
chr19_-_43912392 0.25 ENSMUST00000026209.4
dynamin binding protein
chr1_-_153851189 0.24 ENSMUST00000059607.6
RIKEN cDNA 5830403L16 gene
chr2_-_131328982 0.23 ENSMUST00000110194.1
ring finger protein 24
chr10_+_79996479 0.22 ENSMUST00000132517.1
ATP-binding cassette, sub-family A (ABC1), member 7
chr2_+_147361925 0.22 ENSMUST00000126068.1
paired box gene 1
chr8_+_94386486 0.22 ENSMUST00000034220.7
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr3_+_90526849 0.21 ENSMUST00000167598.2
ENSMUST00000164481.2
S100 calcium binding protein A14
chr8_-_47533439 0.21 ENSMUST00000039061.8
trafficking protein particle complex 11
chr3_-_127408937 0.21 ENSMUST00000183095.1
ENSMUST00000182610.1
ankyrin 2, brain
chr11_+_54303798 0.20 ENSMUST00000093106.5
acyl-CoA synthetase long-chain family member 6
chr17_+_34898463 0.20 ENSMUST00000114033.2
ENSMUST00000078061.6
euchromatic histone lysine N-methyltransferase 2
chr1_+_165461037 0.20 ENSMUST00000027853.5
mitochondrial pyruvate carrier 2
chr16_-_87432597 0.20 ENSMUST00000039449.7
listerin E3 ubiquitin protein ligase 1
chr8_+_45627709 0.20 ENSMUST00000134321.1
ENSMUST00000135336.1
sorbin and SH3 domain containing 2
chr18_+_37307445 0.20 ENSMUST00000056712.2
protocadherin beta 4
chr11_-_116199040 0.19 ENSMUST00000066587.5
acyl-Coenzyme A oxidase 1, palmitoyl
chr9_-_105521147 0.19 ENSMUST00000176770.1
ENSMUST00000085133.6
ATPase, Ca++-sequestering
chr8_+_94386438 0.19 ENSMUST00000161576.1
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr5_-_114273702 0.19 ENSMUST00000144050.1
ENSMUST00000044790.5
forkhead box N4
chr5_+_137553517 0.18 ENSMUST00000136088.1
ENSMUST00000139395.1
ENSMUST00000136565.1
ENSMUST00000149292.1
ENSMUST00000125489.1
actin-like 6B
chr10_+_18055711 0.18 ENSMUST00000154718.1
ENSMUST00000126390.1
ENSMUST00000164556.1
ENSMUST00000150029.1
RalBP1 associated Eps domain containing protein
chr16_+_4939099 0.17 ENSMUST00000050881.8
nudix (nucleoside diphosphate linked moiety X)-type motif 16-like 1
chr14_+_20348159 0.17 ENSMUST00000090503.4
ENSMUST00000090499.5
ENSMUST00000037698.5
ENSMUST00000051915.6
family with sequence similarity 149, member B
chr8_+_47533639 0.15 ENSMUST00000033973.7
ENSMUST00000176379.1
RWD domain containing 4A
chr8_-_64693027 0.15 ENSMUST00000048967.7
carboxypeptidase E
chr2_+_90904740 0.15 ENSMUST00000111464.1
ENSMUST00000090682.3
kelch repeat and BTB (POZ) domain containing 4
chr3_-_127409014 0.14 ENSMUST00000182008.1
ENSMUST00000182711.1
ENSMUST00000182547.1
ankyrin 2, brain
chr11_-_59163696 0.14 ENSMUST00000137433.1
ENSMUST00000054523.5
IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae)
chr14_-_79868398 0.14 ENSMUST00000179430.1
predicted gene 10845
chr14_+_60732906 0.13 ENSMUST00000162945.1
spermatogenesis associated 13
chr11_+_101070012 0.13 ENSMUST00000001802.9
alpha-N-acetylglucosaminidase (Sanfilippo disease IIIB)
chr6_-_71322200 0.13 ENSMUST00000173297.1
ENSMUST00000114188.2
SET and MYND domain containing 1
chr4_-_117765550 0.13 ENSMUST00000062747.5
Kruppel-like factor 17
chr8_+_123443288 0.12 ENSMUST00000108830.1
differentially expressed in FDCP 8
chr16_-_4939579 0.11 ENSMUST00000181498.1
predicted gene, 16861
chr16_+_35983307 0.08 ENSMUST00000004054.6
karyopherin (importin) alpha 1
chr18_+_37355271 0.08 ENSMUST00000051163.1
protocadherin beta 8
chr16_+_35983424 0.08 ENSMUST00000173555.1
karyopherin (importin) alpha 1
chr3_-_127409044 0.08 ENSMUST00000182704.1
ankyrin 2, brain
chr5_+_31526989 0.08 ENSMUST00000114533.2
ENSMUST00000117262.1
ENSMUST00000117319.1
solute carrier family 4 (anion exchanger), member 1, adaptor protein
chr11_+_110997487 0.07 ENSMUST00000106635.1
potassium inwardly-rectifying channel, subfamily J, member 16
chr11_-_61930197 0.07 ENSMUST00000108710.1
A kinase (PRKA) anchor protein 10
chr12_-_69681795 0.06 ENSMUST00000183277.1
ENSMUST00000035773.7
son of sevenless homolog 2 (Drosophila)
chr9_+_20644851 0.06 ENSMUST00000161882.1
ubiquitin-like 5
chr11_+_116198853 0.05 ENSMUST00000021130.6
TEN1 telomerase capping complex subunit
chr2_+_181837854 0.05 ENSMUST00000029116.7
ENSMUST00000108754.1
protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2
chr5_+_32458974 0.05 ENSMUST00000015100.8
protein phosphatase 1, catalytic subunit, beta isoform
chr5_+_76951307 0.05 ENSMUST00000031160.9
ENSMUST00000120912.1
ENSMUST00000117536.1
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoribosylaminoimidazole, succinocarboxamide synthetase
chr19_-_10678001 0.04 ENSMUST00000025647.5
pepsinogen 5, group I
chr9_+_108080436 0.04 ENSMUST00000035211.7
ENSMUST00000162886.1
macrophage stimulating 1 (hepatocyte growth factor-like)
chr6_+_71322775 0.04 ENSMUST00000065248.7
CD8 antigen, beta chain 1
chr9_+_20644792 0.04 ENSMUST00000162303.1
ENSMUST00000161486.1
ubiquitin-like 5
chr11_+_95261529 0.03 ENSMUST00000021242.4
tachykinin 4
chr7_-_126377401 0.03 ENSMUST00000119846.1
ENSMUST00000119754.1
ENSMUST00000032994.8
spinster homolog 1
chr6_-_115675871 0.03 ENSMUST00000112949.1
v-raf-leukemia viral oncogene 1
chr6_+_120093348 0.03 ENSMUST00000112711.2
ninjurin 2
chr18_+_40258361 0.03 ENSMUST00000091927.4
potassium channel tetramerisation domain containing 16
chr10_+_84917616 0.03 ENSMUST00000038523.7
ENSMUST00000095385.3
resistance to inhibitors of cholinesterase 8 homolog B (C. elegans)
chr8_+_45627946 0.03 ENSMUST00000145458.1
sorbin and SH3 domain containing 2
chr4_+_101550411 0.02 ENSMUST00000094953.4
ENSMUST00000106933.1
DnaJ (Hsp40) homolog, subfamily C, member 6
chr11_+_75486813 0.01 ENSMUST00000018449.4
ENSMUST00000102510.1
ENSMUST00000131283.1
pre-mRNA processing factor 8
chr17_-_15564322 0.01 ENSMUST00000147532.1
PR domain containing 9

Network of associatons between targets according to the STRING database.

First level regulatory network of Ddit3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.4 GO:0002325 peptidoglycan metabolic process(GO:0000270) natural killer cell differentiation involved in immune response(GO:0002325) peptidoglycan catabolic process(GO:0009253) negative regulation of natural killer cell differentiation(GO:0032824) regulation of natural killer cell differentiation involved in immune response(GO:0032826) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827)
0.8 2.3 GO:0003137 Notch signaling pathway involved in heart induction(GO:0003137) regulation of Notch signaling pathway involved in heart induction(GO:0035480) positive regulation of Notch signaling pathway involved in heart induction(GO:0035481) regulation of heart induction by regulation of canonical Wnt signaling pathway(GO:0090081)
0.7 3.4 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.6 1.7 GO:0090341 negative regulation of secretion of lysosomal enzymes(GO:0090341)
0.5 3.2 GO:1902998 regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.5 2.6 GO:0060066 oviduct development(GO:0060066)
0.5 1.5 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.4 2.2 GO:1900619 acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.4 1.1 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344) formin-nucleated actin cable assembly(GO:0070649)
0.3 1.5 GO:0010578 regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.3 0.9 GO:0034334 adherens junction maintenance(GO:0034334)
0.3 1.1 GO:1902896 terminal web assembly(GO:1902896)
0.3 1.0 GO:0048496 maintenance of organ identity(GO:0048496)
0.3 0.8 GO:0010841 positive regulation of circadian sleep/wake cycle, wakefulness(GO:0010841)
0.2 3.0 GO:0006751 glutathione catabolic process(GO:0006751)
0.2 0.6 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.2 1.0 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.2 0.8 GO:0002767 immune response-inhibiting cell surface receptor signaling pathway(GO:0002767)
0.2 1.3 GO:0006004 fucose metabolic process(GO:0006004)
0.2 1.5 GO:1904714 Golgi disassembly(GO:0090166) regulation of chaperone-mediated autophagy(GO:1904714)
0.2 0.5 GO:0071798 response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799)
0.1 1.9 GO:0071732 cellular response to nitric oxide(GO:0071732) positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.1 0.4 GO:0002023 reduction of food intake in response to dietary excess(GO:0002023) positive regulation of somatostatin secretion(GO:0090274)
0.1 0.9 GO:0006561 proline biosynthetic process(GO:0006561)
0.1 0.4 GO:0051892 negative regulation of cardioblast differentiation(GO:0051892)
0.1 1.5 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.1 0.8 GO:0090487 toxin catabolic process(GO:0009407) secondary metabolite catabolic process(GO:0090487)
0.1 0.5 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.1 0.8 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.1 0.6 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.1 1.1 GO:0018095 protein polyglutamylation(GO:0018095)
0.1 0.6 GO:0015671 oxygen transport(GO:0015671)
0.1 1.7 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.1 0.7 GO:0018377 protein myristoylation(GO:0018377)
0.1 0.9 GO:0048208 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.1 0.5 GO:0070858 negative regulation of bile acid biosynthetic process(GO:0070858) negative regulation of bile acid metabolic process(GO:1904252)
0.1 0.6 GO:0030242 pexophagy(GO:0030242)
0.1 1.3 GO:0014049 positive regulation of glutamate secretion(GO:0014049)
0.1 0.9 GO:0032308 positive regulation of prostaglandin secretion(GO:0032308)
0.1 0.3 GO:0006409 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.1 0.7 GO:0036309 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.1 0.2 GO:1901074 regulation of engulfment of apoptotic cell(GO:1901074)
0.1 0.4 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
0.1 0.8 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.1 0.4 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.1 0.7 GO:1990403 embryonic brain development(GO:1990403)
0.1 0.2 GO:1901475 pyruvate transmembrane transport(GO:1901475)
0.0 0.2 GO:0030026 cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) manganese ion homeostasis(GO:0055071)
0.0 0.2 GO:0061056 sclerotome development(GO:0061056)
0.0 0.2 GO:0099527 postsynapse to nucleus signaling pathway(GO:0099527)
0.0 0.3 GO:0045916 negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.0 0.2 GO:0030070 insulin processing(GO:0030070)
0.0 0.2 GO:0010747 positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747)
0.0 1.0 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 1.1 GO:1901381 positive regulation of potassium ion transmembrane transport(GO:1901381)
0.0 0.2 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0 0.7 GO:0035067 negative regulation of histone acetylation(GO:0035067)
0.0 0.2 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.0 0.9 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.0 0.8 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.5 GO:0042572 retinol metabolic process(GO:0042572)
0.0 0.3 GO:0051026 chiasma assembly(GO:0051026)
0.0 0.3 GO:0071280 cellular response to copper ion(GO:0071280)
0.0 0.5 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.4 GO:0015874 norepinephrine transport(GO:0015874)
0.0 0.3 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.0 0.4 GO:0035634 response to stilbenoid(GO:0035634) response to phenylpropanoid(GO:0080184)
0.0 0.6 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.1 GO:0071314 cellular response to cocaine(GO:0071314)
0.0 0.2 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 2.4 GO:0007605 sensory perception of sound(GO:0007605)
0.0 0.5 GO:0009409 response to cold(GO:0009409)
0.0 0.3 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0 0.2 GO:0035881 amacrine cell differentiation(GO:0035881)
0.0 0.0 GO:0046878 positive regulation of saliva secretion(GO:0046878)
0.0 0.5 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.2 GO:0090026 positive regulation of monocyte chemotaxis(GO:0090026)
0.0 0.1 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.0 GO:0071550 death-inducing signaling complex assembly(GO:0071550)
0.0 0.6 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:1990696 USH2 complex(GO:1990696)
0.2 3.2 GO:0097418 neurofibrillary tangle(GO:0097418)
0.2 0.6 GO:0033193 Lsd1/2 complex(GO:0033193)
0.2 2.6 GO:0043219 flotillin complex(GO:0016600) lateral loop(GO:0043219)
0.2 2.7 GO:0043083 synaptic cleft(GO:0043083)
0.2 3.4 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 1.1 GO:1990357 terminal web(GO:1990357)
0.1 0.3 GO:0005713 recombination nodule(GO:0005713)
0.1 0.4 GO:1990037 Lewy body core(GO:1990037)
0.1 0.7 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.1 1.1 GO:0031045 dense core granule(GO:0031045)
0.1 1.4 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 0.8 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 1.9 GO:0030673 axolemma(GO:0030673)
0.0 1.0 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.5 GO:1904115 axon cytoplasm(GO:1904115)
0.0 0.8 GO:0042611 MHC protein complex(GO:0042611)
0.0 0.3 GO:0032279 asymmetric synapse(GO:0032279)
0.0 2.5 GO:0043195 terminal bouton(GO:0043195)
0.0 1.5 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 1.0 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.4 GO:0043196 varicosity(GO:0043196)
0.0 5.8 GO:0098791 Golgi subcompartment(GO:0098791)
0.0 0.6 GO:0031430 M band(GO:0031430)
0.0 0.3 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.7 GO:0035869 ciliary transition zone(GO:0035869)
0.0 0.2 GO:0030008 TRAPP complex(GO:0030008)
0.0 1.4 GO:0005581 collagen trimer(GO:0005581)
0.0 0.5 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 2.2 GO:0031225 anchored component of membrane(GO:0031225)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.4 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745) peptidoglycan receptor activity(GO:0016019)
0.6 3.0 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.5 2.2 GO:0004104 cholinesterase activity(GO:0004104)
0.4 1.3 GO:0004560 alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928)
0.3 1.7 GO:0032810 sterol response element binding(GO:0032810)
0.3 1.1 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.3 0.8 GO:0030613 oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672) oxidoreductase activity, acting on phosphorus or arsenic in donors(GO:0030613) oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor(GO:0030614) glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
0.2 0.9 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.2 0.6 GO:0004947 bradykinin receptor activity(GO:0004947)
0.2 0.7 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.2 2.6 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 0.4 GO:0005333 norepinephrine transmembrane transporter activity(GO:0005333)
0.1 3.2 GO:0051787 misfolded protein binding(GO:0051787)
0.1 0.4 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.1 1.0 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.1 0.6 GO:0005344 oxygen transporter activity(GO:0005344)
0.1 1.7 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.1 1.9 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 0.2 GO:0034188 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.1 0.7 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1 0.4 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.1 0.8 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 0.2 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.0 0.8 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.2 GO:0015410 manganese-transporting ATPase activity(GO:0015410)
0.0 0.9 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.5 GO:0004955 prostaglandin receptor activity(GO:0004955)
0.0 0.3 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 1.1 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.5 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.2 GO:0016401 palmitoyl-CoA oxidase activity(GO:0016401)
0.0 0.5 GO:0008106 alcohol dehydrogenase (NADP+) activity(GO:0008106)
0.0 1.0 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.3 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 0.8 GO:0042605 peptide antigen binding(GO:0042605)
0.0 1.8 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.9 GO:0003785 actin monomer binding(GO:0003785)
0.0 3.1 GO:0035326 enhancer binding(GO:0035326)
0.0 1.8 GO:0005179 hormone activity(GO:0005179)
0.0 1.5 GO:0002039 p53 binding(GO:0002039)
0.0 0.6 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.9 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.9 GO:0008146 sulfotransferase activity(GO:0008146)
0.0 2.5 GO:0002020 protease binding(GO:0002020)
0.0 0.5 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 1.0 GO:0005518 collagen binding(GO:0005518)
0.0 0.2 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.2 GO:0050072 m7G(5')pppN diphosphatase activity(GO:0050072)
0.0 0.1 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.2 GO:0102391 decanoate--CoA ligase activity(GO:0102391)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.6 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.9 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 3.0 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 2.2 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 1.7 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 1.2 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 1.0 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 1.0 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.9 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 1.5 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.6 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 1.7 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 1.4 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 2.2 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.1 1.9 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0 0.8 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.5 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.9 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.8 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 1.1 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 1.5 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.0 0.5 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 1.5 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 2.6 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.4 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 1.0 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.8 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.5 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.4 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 1.3 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.9 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.7 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.5 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.2 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.2 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.2 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis