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12D miR HR13_24

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Results for Mnx1_Lhx6_Lmx1a

Z-value: 1.47

Motif logo

Transcription factors associated with Mnx1_Lhx6_Lmx1a

Gene Symbol Gene ID Gene Info
ENSMUSG00000001566.8 motor neuron and pancreas homeobox 1
ENSMUSG00000026890.13 LIM homeobox protein 6
ENSMUSG00000026686.8 LIM homeobox transcription factor 1 alpha

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Mnx1mm10_v2_chr5_-_29478470_294785970.875.4e-04Click!
Lmx1amm10_v2_chr1_+_167689552_1676895630.682.1e-02Click!
Lhx6mm10_v2_chr2_-_36104060_361040730.662.7e-02Click!

Activity profile of Mnx1_Lhx6_Lmx1a motif

Sorted Z-values of Mnx1_Lhx6_Lmx1a motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_25372315 4.48 ENSMUST00000028329.6
ENSMUST00000114293.2
ENSMUST00000100323.2
suppressor APC domain containing 2
chr10_+_4611971 4.19 ENSMUST00000105590.1
ENSMUST00000067086.7
estrogen receptor 1 (alpha)
chr3_-_49757257 4.19 ENSMUST00000035931.7
protocadherin 18
chr9_+_65890237 4.02 ENSMUST00000045802.6
RIKEN cDNA 2810417H13 gene
chr18_+_23415400 3.99 ENSMUST00000115832.2
ENSMUST00000047954.7
dystrobrevin alpha
chr16_-_45724600 3.86 ENSMUST00000096057.4
transgelin 3
chr9_+_32116040 3.42 ENSMUST00000174641.1
Rho GTPase activating protein 32
chr15_-_79285502 3.13 ENSMUST00000165408.1
BAI1-associated protein 2-like 2
chr9_+_72806874 2.90 ENSMUST00000055535.8
protogenin homolog (Gallus gallus)
chr15_-_79285470 2.66 ENSMUST00000170955.1
BAI1-associated protein 2-like 2
chr3_-_88410295 2.66 ENSMUST00000056370.7
polyamine-modulated factor 1
chrX_-_74246534 2.63 ENSMUST00000101454.2
ENSMUST00000033699.6
filamin, alpha
chr8_-_62123106 2.62 ENSMUST00000034052.6
ENSMUST00000034054.7
annexin A10
chr5_+_104202609 2.56 ENSMUST00000066708.5
dentin matrix protein 1
chr11_+_115334731 2.50 ENSMUST00000106543.1
ENSMUST00000019006.4
otopetrin 3
chr7_+_30493622 2.44 ENSMUST00000058280.6
ENSMUST00000133318.1
ENSMUST00000142575.1
ENSMUST00000131040.1
proline dehydrogenase (oxidase) 2
chr3_+_122044428 2.14 ENSMUST00000013995.8
ATP-binding cassette, sub-family A (ABC1), member 4
chr7_+_64501687 2.14 ENSMUST00000032732.8
amyloid beta (A4) precursor protein-binding, family A, member 2
chr19_-_55241236 1.87 ENSMUST00000069183.6
guanylate cyclase 2g
chr3_+_54361103 1.85 ENSMUST00000107985.3
ENSMUST00000117373.1
ENSMUST00000073012.6
ENSMUST00000081564.6
periostin, osteoblast specific factor
chr6_+_145934113 1.81 ENSMUST00000032383.7
sarcospan
chr7_-_45830776 1.73 ENSMUST00000107723.2
ENSMUST00000131384.1
glutamate-rich WD repeat containing 1
chr10_+_88091070 1.69 ENSMUST00000048621.7
pro-melanin-concentrating hormone
chr2_+_162987502 1.68 ENSMUST00000117123.1
serum/glucocorticoid regulated kinase 2
chr2_+_162987330 1.67 ENSMUST00000018012.7
serum/glucocorticoid regulated kinase 2
chr5_-_62766153 1.61 ENSMUST00000076623.4
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr12_+_38780284 1.60 ENSMUST00000162563.1
ENSMUST00000161164.1
ENSMUST00000160996.1
ets variant gene 1
chrX_+_169685191 1.59 ENSMUST00000112104.1
ENSMUST00000112107.1
midline 1
chr4_+_108719649 1.54 ENSMUST00000178992.1
RIKEN cDNA 3110021N24 gene
chr5_+_118169712 1.49 ENSMUST00000054836.6
harakiri, BCL2 interacting protein (contains only BH3 domain)
chrM_+_2743 1.49 ENSMUST00000082392.1
mitochondrially encoded NADH dehydrogenase 1
chr11_-_87359011 1.46 ENSMUST00000055438.4
protein phosphatase 1E (PP2C domain containing)
chr6_-_136781718 1.44 ENSMUST00000078095.6
ENSMUST00000032338.7
guanylate cyclase 2c
chr1_-_158356258 1.43 ENSMUST00000004133.8
bone morphogenic protein/retinoic acid inducible neural-specific 2
chr3_+_68572245 1.43 ENSMUST00000170788.2
schwannomin interacting protein 1
chr6_+_8948608 1.42 ENSMUST00000160300.1
neurexophilin 1
chr12_+_38780817 1.41 ENSMUST00000160856.1
ets variant gene 1
chrX_+_166344692 1.36 ENSMUST00000112223.1
ENSMUST00000112224.1
ENSMUST00000112229.2
ENSMUST00000112228.1
ENSMUST00000112227.2
ENSMUST00000112226.2
glycoprotein m6b
chr3_+_55782500 1.33 ENSMUST00000075422.4
mab-21-like 1 (C. elegans)
chrX_+_134308084 1.33 ENSMUST00000081064.5
ENSMUST00000101251.1
ENSMUST00000129782.1
centromere protein I
chrX_-_134111852 1.32 ENSMUST00000033610.6
NADPH oxidase 1
chr18_+_4993795 1.26 ENSMUST00000153016.1
supervillin
chr8_-_31918203 1.23 ENSMUST00000073884.4
neuregulin 1
chrX_+_150547375 1.23 ENSMUST00000066337.6
ENSMUST00000112715.1
aminolevulinic acid synthase 2, erythroid
chrX_-_102157065 1.21 ENSMUST00000056904.2
excision repair cross-complementing rodent repair deficiency complementation group 6 like
chr7_+_64502090 1.17 ENSMUST00000137732.1
amyloid beta (A4) precursor protein-binding, family A, member 2
chr16_-_63864114 1.16 ENSMUST00000064405.6
Eph receptor A3
chr5_-_138170992 1.12 ENSMUST00000139983.1
minichromosome maintenance deficient 7 (S. cerevisiae)
chr2_-_45117349 1.07 ENSMUST00000176438.2
zinc finger E-box binding homeobox 2
chr6_+_34746368 1.04 ENSMUST00000142716.1
caldesmon 1
chr19_-_15924560 1.03 ENSMUST00000162053.1
phosphoserine aminotransferase 1
chr11_-_87108656 1.02 ENSMUST00000051395.8
proline rich 11
chr16_-_92400067 1.02 ENSMUST00000023672.8
regulator of calcineurin 1
chr6_-_136875794 1.01 ENSMUST00000032342.1
matrix Gla protein
chr15_-_103215285 1.01 ENSMUST00000122182.1
ENSMUST00000108813.3
ENSMUST00000127191.1
chromobox 5
chr11_+_115307155 1.01 ENSMUST00000055490.2
otopetrin 2
chr4_-_99654983 1.00 ENSMUST00000136525.1
predicted gene 12688
chr5_-_84417359 1.00 ENSMUST00000113401.1
Eph receptor A5
chrX_-_150657392 1.00 ENSMUST00000151403.2
ENSMUST00000087253.4
ENSMUST00000112709.1
ENSMUST00000163969.1
ENSMUST00000087258.3
trophinin
chr3_-_33082004 0.98 ENSMUST00000108225.3
peroxisomal biogenesis factor 5-like
chr2_-_33086366 0.98 ENSMUST00000049618.2
GTPase activating RANGAP domain-like 3
chr11_+_23306910 0.98 ENSMUST00000137823.1
ubiquitin specific peptidase 34
chr15_+_55307743 0.97 ENSMUST00000023053.5
ENSMUST00000110221.2
ENSMUST00000110217.3
collagen, type XIV, alpha 1
chr5_+_87925579 0.96 ENSMUST00000001667.6
ENSMUST00000113267.1
casein kappa
chr3_+_94372794 0.96 ENSMUST00000029795.3
RAR-related orphan receptor gamma
chr2_+_119047129 0.96 ENSMUST00000153300.1
ENSMUST00000028799.5
cancer susceptibility candidate 5
chr1_+_53061637 0.94 ENSMUST00000027269.5
myostatin
chr9_+_96258697 0.93 ENSMUST00000179416.1
transcription factor Dp 2
chr19_-_15924928 0.93 ENSMUST00000025542.3
phosphoserine aminotransferase 1
chr3_-_116253467 0.92 ENSMUST00000090473.5
G-protein coupled receptor 88
chr8_-_122460666 0.92 ENSMUST00000006762.5
snail homolog 3 (Drosophila)
chr7_-_45103747 0.89 ENSMUST00000003512.7
Fc receptor, IgG, alpha chain transporter
chr9_-_20959785 0.89 ENSMUST00000177754.1
DNA methyltransferase (cytosine-5) 1
chr6_+_63255971 0.88 ENSMUST00000159561.1
ENSMUST00000095852.3
glutamate receptor, ionotropic, delta 2
chr6_+_71909046 0.87 ENSMUST00000055296.8
polymerase (RNA) I polypeptide A
chrM_+_9452 0.87 ENSMUST00000082411.1
mitochondrially encoded NADH dehydrogenase 3
chr18_-_75697639 0.86 ENSMUST00000165559.1
CBP80/20-dependent translation initiation factor
chr11_+_23306884 0.85 ENSMUST00000180046.1
ubiquitin specific peptidase 34
chr2_-_28916412 0.85 ENSMUST00000050776.2
ENSMUST00000113849.1
BarH-like 1 (Drosophila)
chr15_+_92597104 0.85 ENSMUST00000035399.8
PDZ domain containing RING finger 4
chr2_+_116067213 0.83 ENSMUST00000152412.1
RIKEN cDNA G630016G05 gene
chr19_+_30232921 0.83 ENSMUST00000025797.5
mannose-binding lectin (protein C) 2
chrX_-_150657366 0.81 ENSMUST00000148604.1
trophinin
chr7_-_116198487 0.80 ENSMUST00000181981.1
pleckstrin homology domain containing, family A member 7
chr2_+_152754156 0.79 ENSMUST00000010020.5
cytochrome c oxidase subunit IV isoform 2
chr1_+_161494649 0.77 ENSMUST00000086084.1
tumor necrosis factor (ligand) superfamily, member 18
chr3_-_130730375 0.76 ENSMUST00000079085.6
ribosomal protein L34
chr7_-_38019505 0.76 ENSMUST00000085513.4
URI1, prefoldin-like chaperone
chr6_+_15196949 0.75 ENSMUST00000151301.1
ENSMUST00000131414.1
ENSMUST00000140557.1
ENSMUST00000115469.1
forkhead box P2
chrX_-_74246364 0.75 ENSMUST00000130007.1
filamin, alpha
chr1_+_63176818 0.75 ENSMUST00000129339.1
eukaryotic translation elongation factor 1 beta 2
chr17_+_12119274 0.75 ENSMUST00000024594.2
1-acylglycerol-3-phosphate O-acyltransferase 4 (lysophosphatidic acid acyltransferase, delta)
chr17_-_48432723 0.74 ENSMUST00000046549.3
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 2
chrM_+_7005 0.73 ENSMUST00000082405.1
mitochondrially encoded cytochrome c oxidase II
chr1_+_40515362 0.72 ENSMUST00000027237.5
interleukin 18 receptor accessory protein
chr3_-_94436574 0.72 ENSMUST00000029787.4
ornithine decarboxylase antizyme 3
chr2_+_181767040 0.72 ENSMUST00000108756.1
myelin transcription factor 1
chr17_-_45733843 0.71 ENSMUST00000178179.1
RIKEN cDNA 1600014C23 gene
chr2_-_17460610 0.71 ENSMUST00000145492.1
nebulette
chr1_-_172027269 0.70 ENSMUST00000027837.6
ENSMUST00000111264.1
vang-like 2 (van gogh, Drosophila)
chr18_-_24603464 0.70 ENSMUST00000154205.1
solute carrier family 39 (metal ion transporter), member 6
chr13_-_97747399 0.69 ENSMUST00000144993.1
RIKEN cDNA 5330416C01 gene
chr2_+_181767283 0.69 ENSMUST00000108757.2
myelin transcription factor 1
chr1_-_63176653 0.69 ENSMUST00000027111.8
ENSMUST00000168099.2
NADH dehydrogenase (ubiquinone) Fe-S protein 1
chr11_+_116843278 0.68 ENSMUST00000106370.3
methyltransferase like 23
chr19_+_44992127 0.68 ENSMUST00000179305.1
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chr12_-_73047179 0.65 ENSMUST00000050029.7
sine oculis-related homeobox 1
chr6_+_7555053 0.65 ENSMUST00000090679.2
ENSMUST00000184986.1
tachykinin 1
chr1_-_152625212 0.65 ENSMUST00000027760.7
ral guanine nucleotide dissociation stimulator,-like 1
chr12_+_38781093 0.64 ENSMUST00000161513.1
ets variant gene 1
chr7_-_46667375 0.63 ENSMUST00000107669.2
tryptophan hydroxylase 1
chr12_-_54986328 0.61 ENSMUST00000038926.6
bromodomain adjacent to zinc finger domain 1A
chr5_+_135106881 0.61 ENSMUST00000005507.3
MLX interacting protein-like
chr3_-_130730310 0.60 ENSMUST00000062601.7
ribosomal protein L34
chr12_-_54986363 0.58 ENSMUST00000173433.1
ENSMUST00000173803.1
bromodomain adjacent to zinc finger domain 1A
predicted gene 20403
chr19_+_44493472 0.58 ENSMUST00000041163.4
wingless related MMTV integration site 8b
chr2_-_28916668 0.58 ENSMUST00000113847.1
BarH-like 1 (Drosophila)
chr16_-_89818338 0.57 ENSMUST00000164263.2
T cell lymphoma invasion and metastasis 1
chr5_+_87925624 0.55 ENSMUST00000113271.2
casein kappa
chr8_-_84662841 0.55 ENSMUST00000060427.4
immediate early response 2
chrX_+_56779437 0.55 ENSMUST00000114773.3
four and a half LIM domains 1
chr9_+_7571396 0.54 ENSMUST00000120900.1
ENSMUST00000093896.3
ENSMUST00000151853.1
ENSMUST00000152878.1
matrix metallopeptidase 27
chr2_-_174346712 0.54 ENSMUST00000168292.1
predicted gene, 20721
chr10_+_85386813 0.53 ENSMUST00000105307.1
ENSMUST00000020231.3
BTB (POZ) domain containing 11
chr6_+_125552948 0.53 ENSMUST00000112254.1
ENSMUST00000112253.1
ENSMUST00000001995.7
Von Willebrand factor homolog
chr18_+_24603952 0.53 ENSMUST00000025120.6
elongator acetyltransferase complex subunit 2
chr7_+_103550368 0.53 ENSMUST00000106888.1
olfactory receptor 613
chr1_-_183147461 0.52 ENSMUST00000171366.1
dispatched homolog 1 (Drosophila)
chr2_+_20737306 0.52 ENSMUST00000114606.1
ENSMUST00000114608.1
enhancer trap locus 4
chr2_+_65620829 0.52 ENSMUST00000028377.7
sodium channel, voltage-gated, type II, alpha 1
chr16_-_5013505 0.51 ENSMUST00000023191.10
ENSMUST00000090453.5
rogdi homolog (Drosophila)
chr3_-_87174657 0.51 ENSMUST00000159976.1
ENSMUST00000107618.2
kin of IRRE like (Drosophila)
chr9_+_113812547 0.51 ENSMUST00000166734.2
ENSMUST00000111838.2
ENSMUST00000163895.2
CLIP associating protein 2
chr9_-_55919605 0.51 ENSMUST00000037408.8
S phase cyclin A-associated protein in the ER
chr15_-_43869993 0.50 ENSMUST00000067469.4
transmembrane protein 74
chr15_-_9140374 0.50 ENSMUST00000096482.3
ENSMUST00000110585.2
S-phase kinase-associated protein 2 (p45)
chr3_+_68869563 0.50 ENSMUST00000054551.2
RIKEN cDNA 1110032F04 gene
chr10_+_128337761 0.49 ENSMUST00000005826.7
citrate synthase
chr12_+_84361968 0.49 ENSMUST00000021661.6
coenzyme Q6 homolog (yeast)
chr2_-_45112890 0.48 ENSMUST00000076836.6
zinc finger E-box binding homeobox 2
chr3_-_89349968 0.48 ENSMUST00000074582.6
ENSMUST00000107448.2
ENSMUST00000029676.5
a disintegrin and metallopeptidase domain 15 (metargidin)
chr5_-_150518164 0.47 ENSMUST00000118769.1
zygote arrest 1-like
chr1_-_172027251 0.47 ENSMUST00000138714.1
vang-like 2 (van gogh, Drosophila)
chr7_-_19399859 0.46 ENSMUST00000047170.3
ENSMUST00000108459.2
kinesin light chain 3
chr5_+_92809372 0.46 ENSMUST00000113054.2
shroom family member 3
chr7_-_30559600 0.46 ENSMUST00000043975.4
ENSMUST00000156241.1
lin-37 homolog (C. elegans)
chr2_-_5676046 0.46 ENSMUST00000114987.3
calcium/calmodulin-dependent protein kinase ID
chr3_-_89349939 0.44 ENSMUST00000107446.1
a disintegrin and metallopeptidase domain 15 (metargidin)
chr7_-_30559828 0.43 ENSMUST00000108164.1
lin-37 homolog (C. elegans)
chr4_-_149126688 0.43 ENSMUST00000030815.2
cortistatin
chr15_-_8710734 0.43 ENSMUST00000005493.7
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr5_-_66514815 0.43 ENSMUST00000161879.1
ENSMUST00000159357.1
amyloid beta (A4) precursor protein-binding, family B, member 2
chr5_-_34660068 0.43 ENSMUST00000041364.9
NOP14 nucleolar protein
chr18_-_24603791 0.42 ENSMUST00000070726.3
solute carrier family 39 (metal ion transporter), member 6
chr12_+_51348019 0.42 ENSMUST00000054308.6
G2/M-phase specific E3 ubiquitin ligase
chr7_+_25681158 0.42 ENSMUST00000108403.3
B9 protein domain 2
chr1_-_75046639 0.42 ENSMUST00000152855.1
nonhomologous end-joining factor 1
chr16_+_22918378 0.42 ENSMUST00000170805.1
fetuin beta
chr19_-_41933276 0.41 ENSMUST00000075280.4
ENSMUST00000112123.2
exosome component 1
chr1_+_134405984 0.41 ENSMUST00000173908.1
cytochrome b5 reductase 1
chr9_+_62858085 0.40 ENSMUST00000034777.6
ENSMUST00000163820.1
calmodulin-like 4
chr3_+_133338936 0.40 ENSMUST00000150386.1
ENSMUST00000125858.1
pyrophosphatase (inorganic) 2
chr7_+_125829653 0.39 ENSMUST00000124223.1
RIKEN cDNA D430042O09 gene
chr3_-_86548268 0.38 ENSMUST00000077524.3
mab-21-like 2 (C. elegans)
chr7_-_46667303 0.37 ENSMUST00000168335.1
tryptophan hydroxylase 1
chr12_+_51348265 0.36 ENSMUST00000119211.1
G2/M-phase specific E3 ubiquitin ligase
chr5_-_114773488 0.36 ENSMUST00000178440.1
ENSMUST00000043283.7
ENSMUST00000112185.2
G protein-coupled receptor kinase-interactor 2
chr5_+_138187485 0.36 ENSMUST00000110934.2
canopy 4 homolog (zebrafish)
chr9_-_106096776 0.36 ENSMUST00000121963.1
collagen, type VI, alpha 4
chr1_-_55226768 0.36 ENSMUST00000027121.8
ENSMUST00000114428.2
raftlin family member 2
chr6_+_124304646 0.35 ENSMUST00000112541.2
ENSMUST00000032234.2
CD163 antigen
chr4_+_140701466 0.35 ENSMUST00000038893.5
ENSMUST00000138808.1
regulator of chromosome condensation 2
chr7_-_101837776 0.35 ENSMUST00000165052.1
inositol polyphosphate phosphatase-like 1
chr1_-_134955847 0.35 ENSMUST00000168381.1
protein phosphatase 1, regulatory (inhibitor) subunit 12B
chr6_-_145865302 0.34 ENSMUST00000111703.1
basic helix-loop-helix family, member e41
chrX_+_153126897 0.34 ENSMUST00000163801.1
forkhead box R2
chr13_+_109685994 0.34 ENSMUST00000074103.5
phosphodiesterase 4D, cAMP specific
chr8_-_36953139 0.34 ENSMUST00000179501.1
deleted in liver cancer 1
chr12_+_3954943 0.33 ENSMUST00000020990.5
pro-opiomelanocortin-alpha
chr2_+_125068118 0.32 ENSMUST00000070353.3
solute carrier family 24, member 5
chr3_+_18054258 0.32 ENSMUST00000026120.6
basic helix-loop-helix family, member e22
chr12_+_30884321 0.32 ENSMUST00000067087.6
family with sequence similarity 150, member B
chr3_-_50443603 0.32 ENSMUST00000029297.4
solute carrier family 7 (cationic amino acid transporter, y+ system), member 11
chr14_-_48665098 0.32 ENSMUST00000118578.1
orthodenticle homolog 2 (Drosophila)
chrX_-_157415286 0.32 ENSMUST00000079945.4
ENSMUST00000138396.1
phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets)
chr13_-_97747373 0.32 ENSMUST00000123535.1
RIKEN cDNA 5330416C01 gene
chrM_+_14138 0.31 ENSMUST00000082421.1
mitochondrially encoded cytochrome b
chr17_+_71019548 0.31 ENSMUST00000073211.5
ENSMUST00000179759.1
myomesin 1
chr2_+_3114220 0.31 ENSMUST00000072955.5
family with sequence similarity 171, member A1
chr10_+_88146992 0.30 ENSMUST00000052355.7
nucleoporin 37
chr7_-_73541738 0.30 ENSMUST00000169922.2
chromodomain helicase DNA binding protein 2
chr2_+_69897220 0.29 ENSMUST00000055758.9
ENSMUST00000112251.2
ubiquitin protein ligase E3 component n-recognin 3
chr15_-_66812593 0.29 ENSMUST00000100572.3
src-like adaptor
chr2_-_85196697 0.29 ENSMUST00000099930.2
ENSMUST00000111601.1
leucine rich repeat containing 55
chr2_+_69897255 0.28 ENSMUST00000131553.1
ubiquitin protein ligase E3 component n-recognin 3
chr17_+_71019503 0.28 ENSMUST00000024847.7
myomesin 1
chr12_+_51348370 0.28 ENSMUST00000121521.1
G2/M-phase specific E3 ubiquitin ligase
chr4_-_96785186 0.28 ENSMUST00000107071.1
predicted gene 12695
chrX_-_150589844 0.28 ENSMUST00000112725.1
ENSMUST00000112720.1
apurinic/apyrimidinic endonuclease 2
chr17_-_70853482 0.28 ENSMUST00000118283.1
TGFB-induced factor homeobox 1

Network of associatons between targets according to the STRING database.

First level regulatory network of Mnx1_Lhx6_Lmx1a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.4 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.9 2.6 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.8 4.2 GO:0060523 prostate epithelial cord elongation(GO:0060523)
0.8 2.4 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.6 1.8 GO:1904209 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.4 2.0 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.4 1.2 GO:0060489 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.4 1.2 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
0.3 1.0 GO:2000852 corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852)
0.3 0.9 GO:0061743 motor learning(GO:0061743)
0.3 1.2 GO:0045726 positive regulation of integrin biosynthetic process(GO:0045726)
0.3 3.9 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.3 1.8 GO:0051365 cellular response to potassium ion starvation(GO:0051365)
0.3 1.4 GO:0051581 negative regulation of neurotransmitter uptake(GO:0051581) negative regulation of serotonin uptake(GO:0051612)
0.3 1.5 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.3 0.8 GO:2000328 regulation of T-helper 17 cell lineage commitment(GO:2000328)
0.3 5.8 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.2 1.7 GO:0042747 negative regulation of synaptic transmission, dopaminergic(GO:0032227) regulation of circadian sleep/wake cycle, REM sleep(GO:0042320) circadian sleep/wake cycle, REM sleep(GO:0042747)
0.2 0.9 GO:0014732 skeletal muscle atrophy(GO:0014732)
0.2 0.9 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.2 0.7 GO:0061055 myotome development(GO:0061055)
0.2 0.6 GO:1900149 positive regulation of Schwann cell migration(GO:1900149)
0.2 0.7 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.2 1.2 GO:0045213 neurotransmitter receptor metabolic process(GO:0045213)
0.2 4.2 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.2 1.6 GO:0035372 protein localization to microtubule(GO:0035372)
0.1 0.9 GO:1904749 regulation of protein localization to nucleolus(GO:1904749)
0.1 0.6 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 0.3 GO:1902256 apoptotic process involved in outflow tract morphogenesis(GO:0003275) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256)
0.1 0.3 GO:0035633 maintenance of blood-brain barrier(GO:0035633)
0.1 0.8 GO:0045218 zonula adherens maintenance(GO:0045218)
0.1 1.0 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
0.1 0.6 GO:0009756 carbohydrate mediated signaling(GO:0009756) hexose mediated signaling(GO:0009757) sugar mediated signaling pathway(GO:0010182) glucose mediated signaling pathway(GO:0010255)
0.1 2.1 GO:0045332 phospholipid translocation(GO:0045332)
0.1 1.1 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 1.7 GO:0006337 nucleosome disassembly(GO:0006337)
0.1 0.5 GO:0038032 termination of G-protein coupled receptor signaling pathway(GO:0038032)
0.1 0.8 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 0.6 GO:0042706 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.1 1.5 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 1.9 GO:0060539 diaphragm development(GO:0060539)
0.1 1.0 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.1 0.3 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.1 0.3 GO:1904245 regulation of polynucleotide adenylyltransferase activity(GO:1904245)
0.1 0.9 GO:1904861 excitatory synapse assembly(GO:1904861)
0.1 1.0 GO:0072615 interleukin-17 secretion(GO:0072615)
0.1 1.1 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.1 0.3 GO:0032685 negative regulation of granulocyte macrophage colony-stimulating factor production(GO:0032685)
0.1 0.5 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.1 0.3 GO:1900377 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.1 1.0 GO:0061377 mammary gland alveolus development(GO:0060749) mammary gland lobule development(GO:0061377)
0.1 1.2 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.1 0.2 GO:2000583 regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584)
0.1 0.8 GO:0098596 vocal learning(GO:0042297) imitative learning(GO:0098596)
0.1 0.9 GO:1900121 negative regulation of receptor binding(GO:1900121)
0.1 1.4 GO:0001553 luteinization(GO:0001553)
0.1 0.8 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 0.2 GO:1904578 response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579)
0.1 1.8 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.1 0.3 GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987)
0.1 2.8 GO:0006182 cGMP biosynthetic process(GO:0006182)
0.1 1.0 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.1 0.2 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.1 0.3 GO:0033762 response to glucagon(GO:0033762)
0.1 1.4 GO:0033194 response to hydroperoxide(GO:0033194)
0.1 0.4 GO:0032596 protein transport into membrane raft(GO:0032596)
0.1 0.5 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.0 0.1 GO:1900239 regulation of phenotypic switching(GO:1900239) negative regulation of vascular associated smooth muscle cell migration(GO:1904753) regulation of cardiac vascular smooth muscle cell differentiation(GO:2000722) positive regulation of cardiac vascular smooth muscle cell differentiation(GO:2000724)
0.0 1.5 GO:0034508 centromere complex assembly(GO:0034508)
0.0 0.3 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 0.5 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0 0.3 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.3 GO:1901844 regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844)
0.0 0.6 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.7 GO:0080111 DNA demethylation(GO:0080111)
0.0 1.8 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.0 0.1 GO:0002439 chronic inflammatory response to antigenic stimulus(GO:0002439)
0.0 0.4 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 0.3 GO:0021957 corpus callosum morphogenesis(GO:0021540) corticospinal tract morphogenesis(GO:0021957)
0.0 0.5 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.0 0.2 GO:0042420 dopamine catabolic process(GO:0042420)
0.0 0.3 GO:0010944 negative regulation of transcription by competitive promoter binding(GO:0010944)
0.0 0.3 GO:0042635 positive regulation of hair cycle(GO:0042635) positive regulation of hair follicle development(GO:0051798)
0.0 0.5 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
0.0 1.5 GO:0007595 lactation(GO:0007595)
0.0 0.7 GO:1901016 regulation of potassium ion transmembrane transporter activity(GO:1901016)
0.0 3.3 GO:0032411 positive regulation of transporter activity(GO:0032411)
0.0 0.2 GO:0051096 positive regulation of helicase activity(GO:0051096)
0.0 1.0 GO:0061050 regulation of cell growth involved in cardiac muscle cell development(GO:0061050)
0.0 0.4 GO:0045187 regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.0 0.1 GO:1905065 cysteine biosynthetic process via cystathionine(GO:0019343) positive regulation of vascular smooth muscle cell differentiation(GO:1905065)
0.0 1.3 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 0.1 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.1 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.0 0.2 GO:0046601 positive regulation of centriole replication(GO:0046601) de novo centriole assembly(GO:0098535)
0.0 0.9 GO:0071385 cellular response to corticosteroid stimulus(GO:0071384) cellular response to glucocorticoid stimulus(GO:0071385)
0.0 0.4 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.0 0.9 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.1 GO:0070094 positive regulation of glucagon secretion(GO:0070094)
0.0 0.1 GO:0007182 common-partner SMAD protein phosphorylation(GO:0007182)
0.0 0.1 GO:2000121 regulation of removal of superoxide radicals(GO:2000121)
0.0 0.1 GO:0050955 thermoception(GO:0050955)
0.0 0.2 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.1 GO:0061621 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.0 0.3 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 0.5 GO:0048266 behavioral response to pain(GO:0048266)
0.0 1.0 GO:0006940 regulation of smooth muscle contraction(GO:0006940)
0.0 0.1 GO:0032277 negative regulation of gonadotropin secretion(GO:0032277)
0.0 0.7 GO:0045471 response to ethanol(GO:0045471)
0.0 0.2 GO:0060573 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.0 0.3 GO:0021756 striatum development(GO:0021756)
0.0 0.2 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 0.4 GO:0038092 nodal signaling pathway(GO:0038092)
0.0 1.8 GO:2001243 negative regulation of intrinsic apoptotic signaling pathway(GO:2001243)
0.0 0.4 GO:0070208 protein heterotrimerization(GO:0070208)
0.0 0.0 GO:0061146 Peyer's patch morphogenesis(GO:0061146)
0.0 0.3 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 0.3 GO:0007379 segment specification(GO:0007379)
0.0 0.2 GO:1903779 regulation of cardiac conduction(GO:1903779)
0.0 3.1 GO:0007266 Rho protein signal transduction(GO:0007266)
0.0 0.0 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.0 0.2 GO:0030903 notochord development(GO:0030903)
0.0 0.1 GO:0035095 behavioral response to nicotine(GO:0035095)
0.0 0.4 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.0 0.2 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.4 GO:0006953 acute-phase response(GO:0006953)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.4 GO:0031523 Myb complex(GO:0031523)
0.6 4.2 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.6 5.8 GO:0071439 clathrin complex(GO:0071439)
0.4 2.7 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.3 1.2 GO:0008623 CHRAC(GO:0008623)
0.3 1.2 GO:0060187 cell pole(GO:0060187)
0.3 5.8 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.2 1.2 GO:0071438 invadopodium membrane(GO:0071438)
0.1 1.0 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.1 0.5 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.1 0.7 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1 1.0 GO:0030478 actin cap(GO:0030478)
0.1 2.8 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 0.3 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.1 0.4 GO:0030689 Noc complex(GO:0030689)
0.1 1.5 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 1.1 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 0.5 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 1.1 GO:0042555 MCM complex(GO:0042555)
0.1 0.8 GO:0005915 zonula adherens(GO:0005915)
0.1 0.4 GO:0032807 DNA ligase IV complex(GO:0032807)
0.1 3.2 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 0.9 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1 0.5 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 0.2 GO:0042585 germinal vesicle(GO:0042585)
0.1 0.8 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.6 GO:0060091 kinocilium(GO:0060091)
0.0 1.0 GO:0010369 chromocenter(GO:0010369)
0.0 0.4 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.9 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.3 GO:0045275 respiratory chain complex III(GO:0045275)
0.0 1.0 GO:0043034 costamere(GO:0043034)
0.0 0.3 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 3.1 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.5 GO:0032982 myosin filament(GO:0032982)
0.0 0.5 GO:0070469 respiratory chain(GO:0070469)
0.0 0.5 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.3 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.4 GO:0036038 MKS complex(GO:0036038)
0.0 0.2 GO:0098536 deuterosome(GO:0098536)
0.0 1.6 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 3.7 GO:0001650 fibrillar center(GO:0001650)
0.0 0.3 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.1 GO:0032437 cuticular plate(GO:0032437)
0.0 2.4 GO:0000776 kinetochore(GO:0000776)
0.0 1.4 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.2 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.5 GO:0031672 A band(GO:0031672)
0.0 0.9 GO:0098878 ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.0 0.1 GO:0071953 elastic fiber(GO:0071953)
0.0 2.9 GO:0008021 synaptic vesicle(GO:0008021)
0.0 3.6 GO:0043209 myelin sheath(GO:0043209)
0.0 1.0 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.0 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.0 1.2 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 1.3 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.0 GO:0072487 MSL complex(GO:0072487)
0.0 0.1 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.2 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.7 3.4 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.4 1.2 GO:0016748 succinyltransferase activity(GO:0016748)
0.3 1.2 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.2 1.2 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.2 2.2 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.2 1.0 GO:0008142 oxysterol binding(GO:0008142)
0.2 0.7 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.2 0.9 GO:0019770 IgG receptor activity(GO:0019770)
0.2 2.6 GO:0043522 leucine zipper domain binding(GO:0043522)
0.2 1.0 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.2 1.0 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.1 3.4 GO:0017081 chloride channel regulator activity(GO:0017081)
0.1 3.7 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 1.7 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 0.7 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 0.8 GO:0005534 galactose binding(GO:0005534)
0.1 0.3 GO:0071820 N-box binding(GO:0071820)
0.1 0.9 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 2.8 GO:0004383 guanylate cyclase activity(GO:0004383)
0.1 0.3 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
0.1 0.6 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1 0.3 GO:0047256 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.1 0.4 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.1 2.9 GO:0071949 FAD binding(GO:0071949)
0.1 0.3 GO:0008311 double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.1 0.5 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.1 0.3 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.1 0.7 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.1 2.0 GO:0008483 transaminase activity(GO:0008483)
0.1 2.1 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 0.8 GO:0070097 delta-catenin binding(GO:0070097)
0.1 3.8 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 0.5 GO:0019865 immunoglobulin binding(GO:0019865)
0.1 0.9 GO:0001054 RNA polymerase I activity(GO:0001054)
0.1 1.5 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 0.3 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.0 0.2 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.0 2.6 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.2 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.0 0.1 GO:0070698 type I activin receptor binding(GO:0070698)
0.0 0.3 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.5 GO:0002162 dystroglycan binding(GO:0002162)
0.0 2.5 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.4 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.7 GO:0005234 extracellular-glutamate-gated ion channel activity(GO:0005234)
0.0 1.1 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.2 GO:0031013 troponin I binding(GO:0031013)
0.0 0.6 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.5 GO:0015197 peptide transporter activity(GO:0015197)
0.0 0.3 GO:0046030 inositol-polyphosphate 5-phosphatase activity(GO:0004445) inositol trisphosphate phosphatase activity(GO:0046030)
0.0 0.7 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.7 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 1.1 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 1.2 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.3 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 0.1 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.0 0.1 GO:0004145 diamine N-acetyltransferase activity(GO:0004145)
0.0 0.7 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 0.3 GO:0017166 vinculin binding(GO:0017166)
0.0 0.8 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 1.6 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 3.2 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.3 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.3 GO:0048185 activin binding(GO:0048185)
0.0 4.3 GO:0051015 actin filament binding(GO:0051015)
0.0 1.7 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.2 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 8.0 GO:0005543 phospholipid binding(GO:0005543)
0.0 0.5 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.7 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.1 GO:0019158 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 1.0 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 1.5 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 1.0 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.3 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.6 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.3 GO:0008143 poly(A) binding(GO:0008143)
0.0 1.8 GO:0008201 heparin binding(GO:0008201)
0.0 0.1 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.5 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.1 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.0 1.3 GO:0016779 nucleotidyltransferase activity(GO:0016779)
0.0 0.1 GO:0004957 prostaglandin E receptor activity(GO:0004957)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.9 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 4.7 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.1 1.2 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 3.4 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.1 1.2 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.1 2.2 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.5 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 3.1 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 1.0 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 1.0 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 1.0 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 1.5 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.7 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 1.4 PID AP1 PATHWAY AP-1 transcription factor network
0.0 1.0 PID AURORA B PATHWAY Aurora B signaling
0.0 1.1 PID ATR PATHWAY ATR signaling pathway
0.0 1.2 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.3 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 1.3 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.6 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.8 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 1.0 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.9 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.4 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 1.4 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.4 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.4 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 2.3 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.4 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.1 0.8 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 2.0 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 1.1 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.1 7.2 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 2.1 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.1 0.3 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.1 1.2 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 1.1 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.4 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.5 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.9 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.9 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 1.0 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.3 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.5 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.5 REACTOME KINESINS Genes involved in Kinesins
0.0 0.4 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.6 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.3 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.5 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.7 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.2 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 1.0 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.2 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 1.2 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.4 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.2 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.7 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.1 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.1 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.1 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.7 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.3 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events