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12D miR HR13_24

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Results for Gcm1

Z-value: 0.58

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Transcription factors associated with Gcm1

Gene Symbol Gene ID Gene Info
ENSMUSG00000023333.7 glial cells missing homolog 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Gcm1mm10_v2_chr9_+_78051938_780519580.412.1e-01Click!

Activity profile of Gcm1 motif

Sorted Z-values of Gcm1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_+_46396439 1.56 ENSMUST00000025202.6
potassium voltage gated channel, Shaw-related subfamily, member 1
chr7_-_99182681 1.22 ENSMUST00000033001.4
diacylglycerol O-acyltransferase 2
chr7_+_131966446 0.91 ENSMUST00000045840.4
G protein-coupled receptor 26
chr8_-_13254154 0.90 ENSMUST00000033825.4
ADP-ribosylhydrolase like 1
chr8_-_13254068 0.81 ENSMUST00000168498.1
ADP-ribosylhydrolase like 1
chr8_+_13339656 0.79 ENSMUST00000170909.1
transcription factor Dp 1
chr4_-_123342803 0.74 ENSMUST00000102641.3
bone morphogenetic protein 8a
chr7_-_45136231 0.70 ENSMUST00000124300.1
ENSMUST00000085377.5
ribosomal protein L13A
FMS-like tyrosine kinase 3 ligand
chr17_-_32189457 0.68 ENSMUST00000087721.3
ENSMUST00000162117.1
epoxide hydrolase 3
chr8_-_13254096 0.67 ENSMUST00000171619.1
ADP-ribosylhydrolase like 1
chr6_-_113501818 0.67 ENSMUST00000101059.1
proline-rich transmembrane protein 3
chr12_-_30373358 0.56 ENSMUST00000021004.7
syntrophin, gamma 2
chr7_-_68264201 0.53 ENSMUST00000032770.2
pyroglutamyl-peptidase I-like
chr11_+_102268732 0.45 ENSMUST00000036467.4
ankyrin repeat and SOCS box-containing 16
chr1_-_183147461 0.44 ENSMUST00000171366.1
dispatched homolog 1 (Drosophila)
chr4_-_136956784 0.44 ENSMUST00000030420.8
Eph receptor A8
chr17_+_25471564 0.43 ENSMUST00000025002.1
tektin 4
chr6_+_86365673 0.41 ENSMUST00000071492.7
family with sequence similarity 136, member A
chrX_-_75130996 0.34 ENSMUST00000033775.2
membrane protein, palmitoylated
chrX_-_75130914 0.34 ENSMUST00000114091.1
membrane protein, palmitoylated
chr7_-_45694369 0.34 ENSMUST00000040636.6
secretory blood group 1
chr13_+_100108155 0.33 ENSMUST00000129014.1
small EDRK-rich factor 1
chr13_+_8202885 0.32 ENSMUST00000139438.1
ENSMUST00000135574.1
adenosine deaminase, RNA-specific, B2
chr13_+_107031963 0.29 ENSMUST00000095459.1
RIKEN cDNA 3830408C21 gene
chr6_-_124636085 0.28 ENSMUST00000068797.2
predicted gene 5077
chr3_+_138217814 0.27 ENSMUST00000090171.5
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr7_+_119900099 0.27 ENSMUST00000106516.1
LYR motif containing 1
chr1_+_53313622 0.26 ENSMUST00000027265.3
O-sialoglycoprotein endopeptidase-like 1
chr15_-_83251720 0.26 ENSMUST00000164614.1
ENSMUST00000049530.6
alpha 1,4-galactosyltransferase
chr11_-_106613370 0.26 ENSMUST00000128933.1
testis expressed gene 2
chr1_+_53313636 0.25 ENSMUST00000114484.1
O-sialoglycoprotein endopeptidase-like 1
chr14_-_19977249 0.23 ENSMUST00000160013.1
guanine nucleotide binding protein (G protein), gamma 2
chr10_-_71285234 0.22 ENSMUST00000020085.6
ubiquitin-conjugating enzyme E2D 1
chr4_-_116167591 0.22 ENSMUST00000030465.3
ENSMUST00000143426.1
tetraspanin 1
chr9_+_5345414 0.22 ENSMUST00000027009.4
caspase 12
chr14_-_32201869 0.22 ENSMUST00000170331.1
ENSMUST00000013845.6
translocase of inner mitochondrial membrane 23
chr11_+_101246960 0.21 ENSMUST00000107282.3
receptor (calcitonin) activity modifying protein 2
chr9_+_5345450 0.20 ENSMUST00000151332.1
caspase 12
chr14_+_55510445 0.20 ENSMUST00000165262.1
ENSMUST00000074225.4
copine VI
chr13_+_100107997 0.20 ENSMUST00000142155.1
ENSMUST00000022145.8
ENSMUST00000132053.1
small EDRK-rich factor 1
chr2_-_155834845 0.20 ENSMUST00000029143.5
family with sequence similarity 83, member C
chr15_+_79348061 0.18 ENSMUST00000163691.1
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian)
chr14_+_55578360 0.18 ENSMUST00000174259.1
ENSMUST00000174563.1
ENSMUST00000089619.6
ENSMUST00000172738.1
proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
chr9_-_107605295 0.17 ENSMUST00000102529.3
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
chr4_-_156234777 0.17 ENSMUST00000105569.3
kelch-like 17
chr1_-_191164815 0.15 ENSMUST00000171798.1
family with sequence similarity 71, member A
chr8_+_105170668 0.15 ENSMUST00000109395.1
ENSMUST00000109394.1
ENSMUST00000052209.2
ENSMUST00000109392.1
core binding factor beta
chr10_+_80148263 0.14 ENSMUST00000099492.3
ENSMUST00000042057.5
midnolin
chr11_-_77188968 0.14 ENSMUST00000108400.1
EF-hand calcium binding domain 5
chr3_-_102782708 0.13 ENSMUST00000029450.3
ENSMUST00000172026.1
ENSMUST00000170856.1
thyroid stimulating hormone, beta subunit
chr2_-_180225812 0.12 ENSMUST00000015791.5
laminin, alpha 5
chr7_+_4922251 0.11 ENSMUST00000047309.5
N-acetyltransferase 14
chr13_+_55369732 0.11 ENSMUST00000063771.7
regulator of G-protein signaling 14
chr16_-_16869255 0.10 ENSMUST00000075017.4
pre-B lymphocyte gene 1
chr15_-_10470490 0.09 ENSMUST00000136591.1
DnaJ (Hsp40) homolog, subfamily C, member 21
chr7_-_45136102 0.08 ENSMUST00000125500.1
FMS-like tyrosine kinase 3 ligand
chrX_+_73503074 0.08 ENSMUST00000114479.1
ENSMUST00000088429.1
ENSMUST00000033744.5
ATPase, Ca++ transporting, plasma membrane 3
chr11_+_120491840 0.08 ENSMUST00000026899.3
solute carrier family 25 (mitochondrial carrier, dicarboxylate transporter), member 10
chr2_+_181864337 0.08 ENSMUST00000039551.8
polymerase (RNA) III (DNA directed) polypeptide K
chr18_-_39487096 0.07 ENSMUST00000097592.2
ENSMUST00000115571.1
nuclear receptor subfamily 3, group C, member 1
chr19_+_6400523 0.06 ENSMUST00000146831.1
ENSMUST00000035716.8
ENSMUST00000138555.1
ENSMUST00000167240.1
RAS, guanyl releasing protein 2
chr2_-_105904484 0.06 ENSMUST00000122965.1
elongation protein 4 homolog (S. cerevisiae)
chr11_-_98149551 0.06 ENSMUST00000103143.3
F-box and leucine-rich repeat protein 20
chr17_+_8311101 0.05 ENSMUST00000154553.1
SFT2 domain containing 1
chr1_-_153487639 0.05 ENSMUST00000042141.5
DEAH (Asp-Glu-Ala-His) box polypeptide 9
chr15_+_81744848 0.04 ENSMUST00000109554.1
zinc finger CCCH type containing 7B
chr7_+_127296369 0.04 ENSMUST00000170971.1
integrin alpha L
chr13_-_95250166 0.03 ENSMUST00000162153.1
ENSMUST00000160957.2
ENSMUST00000159598.1
ENSMUST00000162412.1
phosphodiesterase 8B
chr2_+_96318014 0.03 ENSMUST00000135431.1
ENSMUST00000162807.2
leucine rich repeat containing 4C
chr3_+_89459325 0.03 ENSMUST00000107410.1
phosphomevalonate kinase
chr5_-_35105691 0.03 ENSMUST00000030986.8
low density lipoprotein receptor-related protein associated protein 1
chr7_-_45136391 0.02 ENSMUST00000146760.1
FMS-like tyrosine kinase 3 ligand
chr6_+_52177498 0.02 ENSMUST00000070587.3
RIKEN cDNA 5730596B20 gene
chr14_-_66213552 0.02 ENSMUST00000178730.1
PTK2 protein tyrosine kinase 2 beta
chr8_-_3720640 0.01 ENSMUST00000062037.6
C-type lectin domain family 4, member g
chr3_+_159599177 0.01 ENSMUST00000029824.8
retinal pigment epithelium 65
chr10_-_13868779 0.00 ENSMUST00000105534.3
androgen-induced 1

Network of associatons between targets according to the STRING database.

First level regulatory network of Gcm1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.4 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.2 0.8 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290)
0.2 1.2 GO:0035356 cellular triglyceride homeostasis(GO:0035356)
0.1 0.5 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1 1.6 GO:1903818 positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.1 0.8 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.1 0.4 GO:0080154 regulation of fertilization(GO:0080154)
0.1 0.3 GO:0006069 ethanol oxidation(GO:0006069)
0.0 0.3 GO:0001575 globoside metabolic process(GO:0001575)
0.0 0.7 GO:0002024 diet induced thermogenesis(GO:0002024)
0.0 0.4 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.0 0.4 GO:0097264 self proteolysis(GO:0097264)
0.0 0.2 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0 0.4 GO:0060539 diaphragm development(GO:0060539)
0.0 0.1 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.2 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.7 GO:0090022 regulation of neutrophil chemotaxis(GO:0090022)
0.0 0.1 GO:1990034 calcium ion export from cell(GO:1990034)
0.0 0.9 GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189)
0.0 0.2 GO:1902916 positive regulation of protein polyubiquitination(GO:1902916)
0.0 0.2 GO:0030150 protein import into mitochondrial matrix(GO:0030150)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.1 0.7 GO:0097452 GAIT complex(GO:0097452)
0.0 0.2 GO:0008537 proteasome activator complex(GO:0008537)
0.0 1.6 GO:0030673 axolemma(GO:0030673)
0.0 0.2 GO:1903440 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.0 0.1 GO:0005610 laminin-5 complex(GO:0005610) laminin-10 complex(GO:0043259)
0.0 0.2 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.4 GO:0097225 sperm midpiece(GO:0097225)
0.0 1.2 GO:0005811 lipid particle(GO:0005811)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.4 GO:0003875 ADP-ribosylarginine hydrolase activity(GO:0003875)
0.4 1.2 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846) retinol O-fatty-acyltransferase activity(GO:0050252)
0.2 0.5 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.1 0.3 GO:0031127 galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.1 0.3 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.1 1.6 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 0.7 GO:0070700 BMP receptor binding(GO:0070700)
0.1 0.2 GO:0031208 POZ domain binding(GO:0031208)
0.0 0.4 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.0 0.6 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.2 GO:0097643 amylin receptor activity(GO:0097643)
0.0 0.4 GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.0 0.1 GO:0015140 malate transmembrane transporter activity(GO:0015140)
0.0 0.4 GO:0015197 peptide transporter activity(GO:0015197)
0.0 0.2 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.2 GO:0015266 protein channel activity(GO:0015266)
0.0 0.0 GO:0033680 ATP-dependent DNA/RNA helicase activity(GO:0033680)
0.0 0.3 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.1 GO:0004883 glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.2 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.8 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.2 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.1 GO:0004000 adenosine deaminase activity(GO:0004000)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.4 PID EPHA FWDPATHWAY EPHA forward signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.3 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 1.6 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.1 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 1.2 REACTOME TRIGLYCERIDE BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.0 0.2 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C