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12D miR HR13_24

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Results for Fosb

Z-value: 0.34

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Transcription factors associated with Fosb

Gene Symbol Gene ID Gene Info
ENSMUSG00000003545.2 FBJ osteosarcoma oncogene B

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Fosbmm10_v2_chr7_-_19310035_193100500.662.9e-02Click!

Activity profile of Fosb motif

Sorted Z-values of Fosb motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_4778141 0.78 ENSMUST00000094892.5
interleukin 11
chr2_+_167777467 0.46 ENSMUST00000139927.1
ENSMUST00000127441.1
predicted gene 14321
chr10_+_88091070 0.38 ENSMUST00000048621.7
pro-melanin-concentrating hormone
chr9_+_7272514 0.36 ENSMUST00000015394.8
matrix metallopeptidase 13
chr5_-_24392012 0.34 ENSMUST00000059401.6
autophagy related 9B
chr1_+_40515362 0.27 ENSMUST00000027237.5
interleukin 18 receptor accessory protein
chr3_-_88503187 0.25 ENSMUST00000120377.1
lamin A
chr14_-_55758458 0.25 ENSMUST00000001497.7
cell death-inducing DNA fragmentation factor, alpha subunit-like effector B
chr17_+_35841668 0.24 ENSMUST00000174124.1
mediator of DNA damage checkpoint 1
chr8_-_41215146 0.24 ENSMUST00000034003.4
fibrinogen-like protein 1
chr3_-_88503331 0.22 ENSMUST00000029699.6
lamin A
chr17_-_45592485 0.21 ENSMUST00000166119.1
solute carrier family 29 (nucleoside transporters), member 1
chr18_+_4994600 0.21 ENSMUST00000140448.1
supervillin
chr3_+_102469918 0.19 ENSMUST00000106925.2
ENSMUST00000035952.3
nerve growth factor
chr17_-_45592262 0.19 ENSMUST00000164769.1
solute carrier family 29 (nucleoside transporters), member 1
chr7_+_127800844 0.18 ENSMUST00000106271.1
ENSMUST00000138432.1
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
chrX_+_73675500 0.17 ENSMUST00000171398.1
solute carrier family 6 (neurotransmitter transporter, creatine), member 8
chr7_-_80401707 0.17 ENSMUST00000120753.1
furin (paired basic amino acid cleaving enzyme)
chr5_-_21785115 0.16 ENSMUST00000115193.1
ENSMUST00000115192.1
ENSMUST00000115195.1
ENSMUST00000030771.5
DnaJ (Hsp40) homolog, subfamily C, member 2
chr6_+_42349826 0.15 ENSMUST00000070635.6
zyxin
chr1_-_12991109 0.15 ENSMUST00000115403.2
ENSMUST00000115402.1
solute carrier organic anion transporter family, member 5A1
chr9_+_78615501 0.15 ENSMUST00000093812.4
CD109 antigen
chr11_-_70015346 0.14 ENSMUST00000018718.7
ENSMUST00000102574.3
acyl-Coenzyme A dehydrogenase, very long chain
chr11_-_100397740 0.13 ENSMUST00000001592.8
ENSMUST00000107403.1
junction plakoglobin
chr14_+_27622433 0.12 ENSMUST00000090302.5
ELKS/RAB6-interacting/CAST family member 2
chr2_+_118663235 0.12 ENSMUST00000099557.3
p21 protein (Cdc42/Rac)-activated kinase 6
chr4_+_42158092 0.12 ENSMUST00000098122.2
predicted gene 13306
chr11_-_120630516 0.11 ENSMUST00000106181.1
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian)
chrX_-_23266751 0.11 ENSMUST00000115316.2
kelch-like 13
chr7_+_126776939 0.10 ENSMUST00000038614.5
ENSMUST00000170882.1
ENSMUST00000106359.1
ENSMUST00000106357.1
ENSMUST00000145762.1
ENSMUST00000132643.1
ENSMUST00000106356.1
yippee-like 3 (Drosophila)
chr9_+_96259246 0.10 ENSMUST00000179065.1
ENSMUST00000165768.2
transcription factor Dp 2
chr6_+_42350000 0.10 ENSMUST00000164375.1
zyxin
chr11_-_102365111 0.10 ENSMUST00000006749.9
solute carrier family 4 (anion exchanger), member 1
chr17_-_35697971 0.09 ENSMUST00000146472.1
discoidin domain receptor family, member 1
chr18_+_40258361 0.09 ENSMUST00000091927.4
potassium channel tetramerisation domain containing 16
chr11_-_69549108 0.09 ENSMUST00000108659.1
dynein, axonemal, heavy chain 2
chr7_-_45920830 0.08 ENSMUST00000164119.1
epithelial membrane protein 3
chr17_+_35841491 0.08 ENSMUST00000082337.6
mediator of DNA damage checkpoint 1
chr11_-_3914664 0.07 ENSMUST00000109995.1
ENSMUST00000051207.1
solute carrier family 35, member E4
chr6_+_29529277 0.07 ENSMUST00000163511.1
interferon regulatory factor 5
chr2_+_151572606 0.07 ENSMUST00000028950.8
syndecan binding protein (syntenin) 2
chr11_+_77801325 0.07 ENSMUST00000151373.2
ENSMUST00000172303.2
ENSMUST00000130305.2
ENSMUST00000164334.1
ENSMUST00000092884.4
myosin XVIIIA
chr2_-_25224653 0.07 ENSMUST00000043584.4
tubulin, beta 4B class IVB
chr7_-_127946725 0.07 ENSMUST00000118755.1
ENSMUST00000094026.3
protease, serine, 36
chr11_+_4257557 0.07 ENSMUST00000066283.5
leukemia inhibitory factor
chr11_+_77801291 0.07 ENSMUST00000100794.3
myosin XVIIIA
chr6_+_86849488 0.06 ENSMUST00000089519.6
ENSMUST00000113668.1
AP2 associated kinase 1
chr11_+_78188422 0.06 ENSMUST00000002128.7
ENSMUST00000150941.1
RAB34, member of RAS oncogene family
chr6_-_113934679 0.06 ENSMUST00000101044.2
ATPase, Ca++ transporting, plasma membrane 2
chr12_+_83632208 0.06 ENSMUST00000048155.9
ENSMUST00000182618.1
ENSMUST00000183154.1
ENSMUST00000182036.1
ENSMUST00000182347.1
RNA binding motif protein 25
chr19_-_38125258 0.06 ENSMUST00000025951.6
retinol binding protein 4, plasma
chr9_-_109059216 0.06 ENSMUST00000112053.1
three prime repair exonuclease 1
chr9_+_96258697 0.06 ENSMUST00000179416.1
transcription factor Dp 2
chr19_+_5447692 0.06 ENSMUST00000025850.5
fos-like antigen 1
chr9_-_32541589 0.06 ENSMUST00000016231.7
Friend leukemia integration 1
chr7_-_100547620 0.06 ENSMUST00000064334.2
RIKEN cDNA D630004N19 gene
chr2_+_30441831 0.06 ENSMUST00000131476.1
protein phosphatase 2A, regulatory subunit B (PR 53)
chr12_-_84194007 0.06 ENSMUST00000110294.1
ELM2 and Myb/SANT-like domain containing 1
chr15_+_102503722 0.05 ENSMUST00000096145.4
predicted gene 10337
chr12_-_85288419 0.05 ENSMUST00000121930.1
acylphosphatase 1, erythrocyte (common) type
chr4_-_43558386 0.05 ENSMUST00000130353.1
talin 1
chr2_-_45110241 0.05 ENSMUST00000177302.1
zinc finger E-box binding homeobox 2
chr18_-_31317043 0.05 ENSMUST00000139924.1
ENSMUST00000153060.1
Ras-like without CAAX 2
chr1_-_51915968 0.05 ENSMUST00000046390.7
myosin IB
chr1_-_171240055 0.05 ENSMUST00000131286.1
NADH dehydrogenase (ubiquinone) Fe-S protein 2
chr5_-_5265224 0.05 ENSMUST00000115450.1
cyclin-dependent kinase 14
chr19_-_32210969 0.04 ENSMUST00000151289.1
sphingomyelin synthase 1
chr9_-_109059711 0.04 ENSMUST00000061973.4
three prime repair exonuclease 1
chr12_+_51690966 0.04 ENSMUST00000021338.8
adaptor-related protein complex AP-4, sigma 1
chr1_+_86064619 0.04 ENSMUST00000027432.8
proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
chr11_+_117232254 0.04 ENSMUST00000106354.2
septin 9
chr6_-_129533267 0.04 ENSMUST00000181594.1
RIKEN cDNA 1700101I11 gene
chr9_+_7445822 0.04 ENSMUST00000034497.6
matrix metallopeptidase 3
chr16_+_78930940 0.03 ENSMUST00000114216.1
ENSMUST00000069148.6
ENSMUST00000023568.7
chondrolectin
chr1_+_134560190 0.03 ENSMUST00000112198.1
ENSMUST00000112197.1
lysine (K)-specific demethylase 5B
chr1_+_134560157 0.03 ENSMUST00000047714.7
lysine (K)-specific demethylase 5B
chrX_+_96455359 0.03 ENSMUST00000033553.7
hephaestin
chr2_-_18048784 0.03 ENSMUST00000142856.1
SKI/DACH domain containing 1
chr11_-_43747963 0.03 ENSMUST00000048578.2
ENSMUST00000109278.1
tetratricopeptide repeat domain 1
chr7_-_29505447 0.03 ENSMUST00000183096.1
ENSMUST00000085809.4
signal-induced proliferation-associated 1 like 3
chr11_+_80428598 0.03 ENSMUST00000173938.1
ENSMUST00000017572.7
proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr15_-_76014318 0.02 ENSMUST00000060807.5
family with sequence similarity 83, member H
chr3_+_55461758 0.02 ENSMUST00000070418.4
doublecortin-like kinase 1
chr9_+_44240668 0.02 ENSMUST00000092426.3
coiled-coil domain containing 153
chr2_+_110721340 0.02 ENSMUST00000111016.2
mucin 15
chr16_-_4880284 0.02 ENSMUST00000037843.6
UBA-like domain containing 1
chr10_-_44458687 0.02 ENSMUST00000105490.2
PR domain containing 1, with ZNF domain
chr11_+_78188806 0.02 ENSMUST00000056241.5
RAB34, member of RAS oncogene family
chr11_-_69666062 0.01 ENSMUST00000108654.2
ENSMUST00000018918.5
CD68 antigen
chr2_+_156475803 0.01 ENSMUST00000029155.8
erythrocyte protein band 4.1-like 1
chr18_+_82910863 0.01 ENSMUST00000171238.1
zinc finger protein 516
chr1_-_74893109 0.01 ENSMUST00000006721.2
crystallin, beta A2
chr2_-_151632471 0.01 ENSMUST00000137936.1
ENSMUST00000146172.1
ENSMUST00000094456.3
ENSMUST00000148755.1
ENSMUST00000109875.1
ENSMUST00000028951.7
ENSMUST00000109877.3
syntaphilin
chr2_+_110721632 0.01 ENSMUST00000090332.4
mucin 15
chr2_+_156475844 0.00 ENSMUST00000103135.1
erythrocyte protein band 4.1-like 1
chr3_+_109573907 0.00 ENSMUST00000106576.2
vav 3 oncogene
chr3_-_88177671 0.00 ENSMUST00000181837.1
RIKEN cDNA 1700113A16 gene

Network of associatons between targets according to the STRING database.

First level regulatory network of Fosb

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.1 0.4 GO:0090187 positive regulation of pancreatic juice secretion(GO:0090187)
0.1 0.3 GO:0044805 late nucleophagy(GO:0044805)
0.1 0.4 GO:0015862 uridine transport(GO:0015862)
0.1 0.2 GO:0015881 creatine transport(GO:0015881)
0.1 0.4 GO:0042320 negative regulation of synaptic transmission, dopaminergic(GO:0032227) regulation of circadian sleep/wake cycle, REM sleep(GO:0042320) circadian sleep/wake cycle, REM sleep(GO:0042747)
0.0 0.2 GO:0090472 dibasic protein processing(GO:0090472)
0.0 0.1 GO:1903027 regulation of opsonization(GO:1903027) positive regulation of opsonization(GO:1903028)
0.0 0.2 GO:0014042 positive regulation of neuron maturation(GO:0014042)
0.0 0.1 GO:0072675 osteoclast fusion(GO:0072675)
0.0 0.1 GO:0071680 response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.0 0.1 GO:2000864 estradiol secretion(GO:0035938) regulation of estradiol secretion(GO:2000864)
0.0 0.2 GO:0035754 B cell chemotaxis(GO:0035754)
0.0 0.1 GO:0072108 positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis(GO:0072108)
0.0 0.1 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.0 0.1 GO:0048807 female genitalia morphogenesis(GO:0048807)
0.0 0.1 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.0 0.2 GO:0035634 response to stilbenoid(GO:0035634) response to phenylpropanoid(GO:0080184)
0.0 0.1 GO:1905169 protein localization to phagocytic vesicle(GO:1905161) regulation of protein localization to phagocytic vesicle(GO:1905169) positive regulation of protein localization to phagocytic vesicle(GO:1905171)
0.0 0.1 GO:0048840 otolith development(GO:0048840)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0005638 lamin filament(GO:0005638)
0.0 0.4 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.1 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 0.0 GO:0097447 dendritic tree(GO:0097447)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0005308 creatine transmembrane transporter activity(GO:0005308)
0.0 0.1 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.0 0.2 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 0.3 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.0 0.2 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 0.1 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 0.2 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.1 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.0 0.1 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.0 0.1 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.0 0.4 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.1 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.4 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 0.2 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.1 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.4 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.2 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 0.7 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)