Project

12D miR HR13_24

Navigation
Downloads

Results for E2f2_E2f5

Z-value: 4.43

Motif logo

Transcription factors associated with E2f2_E2f5

Gene Symbol Gene ID Gene Info
ENSMUSG00000018983.9 E2F transcription factor 2
ENSMUSG00000027552.8 E2F transcription factor 5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
E2f5mm10_v2_chr3_+_14578609_145786870.793.6e-03Click!
E2f2mm10_v2_chr4_+_136172367_1361723950.775.9e-03Click!

Activity profile of E2f2_E2f5 motif

Sorted Z-values of E2f2_E2f5 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr13_-_55329723 19.46 ENSMUST00000021941.7
Max dimerization protein 3
chr10_-_69352886 17.77 ENSMUST00000119827.1
ENSMUST00000020099.5
cyclin-dependent kinase 1
chr4_+_126556935 16.89 ENSMUST00000048391.8
claspin
chr10_+_110745433 15.79 ENSMUST00000174857.1
ENSMUST00000073781.5
ENSMUST00000173471.1
ENSMUST00000173634.1
E2F transcription factor 7
chr8_+_75109528 13.80 ENSMUST00000164309.1
minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae)
chr9_+_122951051 13.78 ENSMUST00000040717.5
kinesin family member 15
chr17_+_56304313 12.06 ENSMUST00000113035.1
ENSMUST00000113039.2
ENSMUST00000142387.1
ubiquitin-like, containing PHD and RING finger domains, 1
chr2_+_150909565 11.70 ENSMUST00000028948.4
GINS complex subunit 1 (Psf1 homolog)
chr15_-_58135047 11.61 ENSMUST00000038194.3
ATPase family, AAA domain containing 2
chr5_-_138171813 11.10 ENSMUST00000155902.1
ENSMUST00000148879.1
minichromosome maintenance deficient 7 (S. cerevisiae)
chr4_+_126556994 11.00 ENSMUST00000147675.1
claspin
chr2_+_72476159 10.95 ENSMUST00000102691.4
cell division cycle associated 7
chr2_-_113848655 10.85 ENSMUST00000102545.1
ENSMUST00000110948.1
Rho GTPase activating protein 11A
chr4_+_136172367 10.78 ENSMUST00000061721.5
E2F transcription factor 2
chrX_-_93632113 10.65 ENSMUST00000006856.2
polymerase (DNA directed), alpha 1
chr4_+_134468320 10.51 ENSMUST00000030636.4
ENSMUST00000127279.1
ENSMUST00000105867.1
stathmin 1
chr1_-_20820213 10.47 ENSMUST00000053266.9
minichromosome maintenance deficient 3 (S. cerevisiae)
chr2_-_113848601 9.97 ENSMUST00000110949.2
Rho GTPase activating protein 11A
chr15_-_55090422 9.75 ENSMUST00000110231.1
ENSMUST00000023059.6
defective in sister chromatid cohesion 1 homolog (S. cerevisiae)
chr6_+_4747306 9.23 ENSMUST00000175823.1
ENSMUST00000176204.1
ENSMUST00000166678.1
paternally expressed 10
chr2_+_72476225 9.16 ENSMUST00000157019.1
cell division cycle associated 7
chr1_-_128359610 9.14 ENSMUST00000027601.4
minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae)
chr4_+_115000156 8.91 ENSMUST00000030490.6
Scl/Tal1 interrupting locus
chr3_+_98013503 8.62 ENSMUST00000079812.6
notch 2
chr12_-_11265768 8.57 ENSMUST00000166117.1
Gen homolog 1, endonuclease (Drosophila)
chr12_+_24708241 8.44 ENSMUST00000020980.5
ribonucleotide reductase M2
chr13_-_24761440 8.16 ENSMUST00000176890.1
ENSMUST00000175689.1
geminin
chr10_-_5805412 7.99 ENSMUST00000019907.7
F-box protein 5
chr4_+_115000174 7.89 ENSMUST00000129957.1
Scl/Tal1 interrupting locus
chr1_-_191575534 7.53 ENSMUST00000027933.5
denticleless homolog (Drosophila)
chr9_-_20952838 7.09 ENSMUST00000004202.9
DNA methyltransferase (cytosine-5) 1
chr11_+_80089385 7.02 ENSMUST00000108239.1
ENSMUST00000017694.5
ATPase family, AAA domain containing 5
chr2_+_119112793 6.88 ENSMUST00000140939.1
ENSMUST00000028795.3
RAD51 homolog
chr6_-_88898664 6.77 ENSMUST00000058011.6
minichromosome maintenance deficient 2 mitotin (S. cerevisiae)
chr13_-_24761861 6.54 ENSMUST00000006898.3
ENSMUST00000110382.2
geminin
chr1_-_86359455 6.50 ENSMUST00000027438.6
nucleolin
chr5_-_138172383 6.30 ENSMUST00000000505.9
minichromosome maintenance deficient 7 (S. cerevisiae)
chr7_-_48881596 6.23 ENSMUST00000119223.1
E2F transcription factor 8
chr7_+_46397648 6.04 ENSMUST00000160433.1
potassium voltage gated channel, Shaw-related subfamily, member 1
chr9_+_65890237 6.03 ENSMUST00000045802.6
RIKEN cDNA 2810417H13 gene
chr7_-_48881032 5.99 ENSMUST00000058745.8
E2F transcription factor 8
chr5_+_110286306 5.90 ENSMUST00000007296.5
ENSMUST00000112482.1
polymerase (DNA directed), epsilon
chr12_+_116405397 5.81 ENSMUST00000084828.3
non-SMC condensin II complex, subunit G2
chr8_+_105348163 5.61 ENSMUST00000073149.5
solute carrier family 9 (sodium/hydrogen exchanger), member 5
chr13_+_92354783 5.54 ENSMUST00000022218.4
dihydrofolate reductase
chr8_-_53638945 5.32 ENSMUST00000047768.4
nei like 3 (E. coli)
chr15_-_9140374 5.25 ENSMUST00000096482.3
ENSMUST00000110585.2
S-phase kinase-associated protein 2 (p45)
chr7_-_44548733 5.24 ENSMUST00000145956.1
ENSMUST00000049343.8
polymerase (DNA directed), delta 1, catalytic subunit
chr16_-_18811615 5.03 ENSMUST00000096990.3
cell division cycle 45
chr17_+_56303396 4.95 ENSMUST00000113038.1
ubiquitin-like, containing PHD and RING finger domains, 1
chr2_+_132816141 4.86 ENSMUST00000028831.8
ENSMUST00000066559.5
minichromosome maintenance deficient 8 (S. cerevisiae)
chr15_+_102296256 4.76 ENSMUST00000064924.4
extra spindle poles-like 1 (S. cerevisiae)
chr14_-_31019055 4.72 ENSMUST00000037739.6
guanine nucleotide binding protein-like 3 (nucleolar)
chr3_+_104638658 4.70 ENSMUST00000046212.1
solute carrier family 16 (monocarboxylic acid transporters), member 1
chr18_+_10617768 4.63 ENSMUST00000002551.3
small nuclear ribonucleoprotein D1
chr5_+_110839973 4.20 ENSMUST00000066160.1
checkpoint kinase 2
chr4_+_132768325 4.14 ENSMUST00000102561.4
replication protein A2
chr12_+_24708984 4.08 ENSMUST00000154588.1
ribonucleotide reductase M2
chrX_-_8074720 4.05 ENSMUST00000115636.3
ENSMUST00000115638.3
suppressor of variegation 3-9 homolog 1 (Drosophila)
chr6_+_113531675 3.85 ENSMUST00000036340.5
ENSMUST00000101051.2
Fanconi anemia, complementation group D2
chr3_+_88532314 3.81 ENSMUST00000172699.1
mex3 homolog A (C. elegans)
chr7_+_29309429 3.78 ENSMUST00000137848.1
D4, zinc and double PHD fingers family 1
chr4_+_129513581 3.66 ENSMUST00000062356.6
MARCKS-like 1
chr7_-_137314394 3.56 ENSMUST00000168203.1
ENSMUST00000106118.2
ENSMUST00000169486.2
ENSMUST00000033378.5
early B cell factor 3
chr1_+_175880775 3.54 ENSMUST00000039725.6
exonuclease 1
chr19_+_8723478 3.45 ENSMUST00000180819.1
ENSMUST00000181422.1
small nucleolar RNA host gene (non-protein coding) 1
chr12_-_69228167 3.36 ENSMUST00000021359.5
polymerase (DNA directed), epsilon 2 (p59 subunit)
chr6_-_47594967 3.33 ENSMUST00000081721.6
ENSMUST00000114618.1
ENSMUST00000114616.1
enhancer of zeste homolog 2 (Drosophila)
chr17_-_23740301 3.33 ENSMUST00000024702.3
progestin and adipoQ receptor family member IV
chr16_-_15637277 3.15 ENSMUST00000023353.3
minichromosome maintenance deficient 4 homolog (S. cerevisiae)
chr9_+_64281575 3.13 ENSMUST00000034964.6
timeless interacting protein
chr17_+_56303321 3.02 ENSMUST00000001258.8
ubiquitin-like, containing PHD and RING finger domains, 1
chr2_-_5012716 2.99 ENSMUST00000027980.7
minichromosome maintenance deficient 10 (S. cerevisiae)
chr9_+_103305156 2.95 ENSMUST00000035164.3
topoisomerase (DNA) II binding protein 1
chr5_+_88764983 2.95 ENSMUST00000031311.9
deoxycytidine kinase
chr6_-_8259098 2.92 ENSMUST00000012627.4
replication protein A3
chr10_+_128232065 2.92 ENSMUST00000055539.4
ENSMUST00000105244.1
ENSMUST00000105243.2
ENSMUST00000125289.1
ENSMUST00000105242.1
timeless circadian clock 1
chr2_+_24949747 2.87 ENSMUST00000028350.3
zinc finger, MYND domain containing 19
chr10_+_13090788 2.85 ENSMUST00000121646.1
ENSMUST00000121325.1
ENSMUST00000121766.1
pleiomorphic adenoma gene-like 1
chr12_+_11265867 2.79 ENSMUST00000020931.5
structural maintenance of chromosomes 6
chr7_-_19359477 2.76 ENSMUST00000047036.8
CD3E antigen, epsilon polypeptide associated protein
chr5_+_139543889 2.72 ENSMUST00000174792.1
ENSMUST00000031523.8
UNC homeobox
chr6_+_51470633 2.72 ENSMUST00000114445.1
ENSMUST00000114446.1
ENSMUST00000141711.1
chromobox 3
chr17_+_23726336 2.71 ENSMUST00000024701.7
protein kinase, membrane associated tyrosine/threonine 1
chr7_+_102441685 2.71 ENSMUST00000033283.9
ribonucleotide reductase M1
chr9_-_97018823 2.65 ENSMUST00000055433.4
splA/ryanodine receptor domain and SOCS box containing 4
chr5_+_143909964 2.62 ENSMUST00000148011.1
ENSMUST00000110709.3
postmeiotic segregation increased 2 (S. cerevisiae)
chr3_+_116594959 2.61 ENSMUST00000029571.8
spindle assembly 6 homolog (C. elegans)
chr4_-_43010226 2.60 ENSMUST00000030165.4
Fanconi anemia, complementation group G
chr9_+_106477269 2.60 ENSMUST00000047721.8
RRP9, small subunit (SSU) processome component, homolog (yeast)
chr13_-_96132568 2.57 ENSMUST00000161263.1
synaptic vesicle glycoprotein 2c
chr6_+_51470510 2.54 ENSMUST00000031862.7
chromobox 3
chr19_-_10203880 2.40 ENSMUST00000142241.1
ENSMUST00000116542.2
ENSMUST00000025651.5
ENSMUST00000156291.1
flap structure specific endonuclease 1
chr7_+_13278778 2.40 ENSMUST00000098814.4
ENSMUST00000146998.1
ENSMUST00000185145.1
ligase I, DNA, ATP-dependent
chr6_-_148946146 2.40 ENSMUST00000132696.1
family with sequence similarity 60, member A
chr5_+_75574916 2.38 ENSMUST00000144270.1
ENSMUST00000005815.6
kit oncogene
chr10_+_24595623 2.32 ENSMUST00000176228.1
ENSMUST00000129142.1
connective tissue growth factor
chr17_+_87672523 2.31 ENSMUST00000172855.1
mutS homolog 2 (E. coli)
chr10_+_80356459 2.30 ENSMUST00000039836.8
ENSMUST00000105351.1
polo-like kinase 5
chr19_-_53371766 2.27 ENSMUST00000086887.1
predicted gene 10197
chr14_-_76010863 2.26 ENSMUST00000088922.4
general transcription factor IIF, polypeptide 2
chr4_+_11191354 2.24 ENSMUST00000170901.1
cyclin E2
chr6_+_49822710 2.09 ENSMUST00000031843.6
neuropeptide Y
chr2_-_34913976 2.06 ENSMUST00000028232.3
PHD finger protein 19
chr7_-_38107490 2.02 ENSMUST00000108023.3
cyclin E1
chr10_+_7667503 2.00 ENSMUST00000040135.8
nucleoporin 43
chr10_+_107271827 1.98 ENSMUST00000020057.8
ENSMUST00000105280.3
lin-7 homolog A (C. elegans)
chr2_+_55437100 1.97 ENSMUST00000112633.2
ENSMUST00000112632.1
potassium inwardly-rectifying channel, subfamily J, member 3
chr4_-_132843111 1.95 ENSMUST00000105919.1
ENSMUST00000030702.7
protein phosphatase 1, regulatory (inhibitor) subunit 8
chr18_+_56707725 1.95 ENSMUST00000025486.8
lamin B1
chr2_-_154569845 1.90 ENSMUST00000103145.4
E2F transcription factor 1
chr11_+_98907801 1.88 ENSMUST00000092706.6
cell division cycle 6
chr8_-_105707933 1.88 ENSMUST00000013299.9
enkurin domain containing 1
chr4_-_136835843 1.87 ENSMUST00000105846.2
ENSMUST00000059287.7
ENSMUST00000105845.2
Eph receptor B2
chr16_-_11203259 1.85 ENSMUST00000119953.1
ribosomal L1 domain containing 1
chr2_-_132253227 1.85 ENSMUST00000028817.6
proliferating cell nuclear antigen
chr19_-_5964132 1.84 ENSMUST00000025752.7
ENSMUST00000165143.1
polymerase (DNA directed), alpha 2
chr9_+_65630552 1.82 ENSMUST00000055844.8
RNA binding protein with multiple splicing 2
chr10_-_80577285 1.80 ENSMUST00000038558.8
Kruppel-like factor 16
chr11_+_88047302 1.79 ENSMUST00000139129.2
serine/arginine-rich splicing factor 1
chr9_-_13827029 1.79 ENSMUST00000148086.1
ENSMUST00000034398.5
centrosomal protein 57
chr10_-_128891674 1.78 ENSMUST00000026408.6
growth differentiation factor 11
chr1_-_9700209 1.74 ENSMUST00000088658.4
myeloblastosis oncogene-like 1
chr13_-_64153194 1.60 ENSMUST00000059817.4
ENSMUST00000117241.1
zinc finger protein 367
chr19_+_53600377 1.60 ENSMUST00000025930.9
structural maintenance of chromosomes 3
chr8_-_120228221 1.58 ENSMUST00000183235.1
RIKEN cDNA A330074K22 gene
chr7_-_127260677 1.57 ENSMUST00000035276.4
dCTP pyrophosphatase 1
chr15_+_8109313 1.56 ENSMUST00000163765.1
nucleoporin 155
chr14_-_20388822 1.53 ENSMUST00000022345.6
DnaJ (Hsp40) homolog, subfamily C, member 9
chr15_+_55557399 1.51 ENSMUST00000022998.7
Mdm2, transformed 3T3 cell double minute p53 binding protein
chr11_-_118569910 1.51 ENSMUST00000136551.1
RNA binding protein, fox-1 homolog (C. elegans) 3
chr9_-_36726374 1.50 ENSMUST00000172702.2
ENSMUST00000172742.1
ENSMUST00000034625.5
checkpoint kinase 1
chr1_-_156474249 1.49 ENSMUST00000051396.6
sterol O-acyltransferase 1
chrX_-_157492280 1.48 ENSMUST00000112529.1
spermine synthase
chr5_-_110839757 1.46 ENSMUST00000056937.5
HscB iron-sulfur cluster co-chaperone homolog (E. coli)
chr1_+_157412352 1.45 ENSMUST00000061537.5
RIKEN cDNA 2810025M15 gene
chr15_-_33687840 1.45 ENSMUST00000042021.3
testis-specific protein, Y-encoded-like 5
chr18_+_45268876 1.43 ENSMUST00000183850.1
ENSMUST00000066890.7
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chr13_-_92354943 1.41 ENSMUST00000022220.6
mutS homolog 3 (E. coli)
chr11_-_100712429 1.40 ENSMUST00000006973.5
ENSMUST00000103118.3
K(lysine) acetyltransferase 2A
chr4_-_133967953 1.37 ENSMUST00000102553.4
high mobility group nucleosomal binding domain 2
chr7_+_79392305 1.37 ENSMUST00000117227.1
ENSMUST00000118959.1
ENSMUST00000036865.6
Fanconi anemia, complementation group I
chr6_+_51470339 1.36 ENSMUST00000094623.3
chromobox 3
chr5_-_34513892 1.36 ENSMUST00000114359.1
ENSMUST00000030991.7
ENSMUST00000087737.3
TNFAIP3 interacting protein 2
chr13_-_106936907 1.33 ENSMUST00000080856.7
importin 11
chr11_+_101119938 1.33 ENSMUST00000043680.8
tubulin, gamma 1
chr2_+_25054355 1.30 ENSMUST00000100334.4
ENSMUST00000152122.1
ENSMUST00000116574.3
ENSMUST00000006646.8
NMDA receptor synaptonuclear signaling and neuronal migration factor
chr2_-_30474199 1.30 ENSMUST00000065134.2
immediate early response 5-like
chr17_-_71475285 1.29 ENSMUST00000127430.1
SMC hinge domain containing 1
chr13_-_35906324 1.27 ENSMUST00000174230.1
ENSMUST00000171686.2
ribonuclease P 40 subunit
chr3_-_145649970 1.26 ENSMUST00000029846.3
cysteine rich protein 61
chr8_+_95633500 1.24 ENSMUST00000034094.9
GINS complex subunit 3 (Psf3 homolog)
chr8_+_70594466 1.24 ENSMUST00000019283.9
myo-inositol 1-phosphate synthase A1
chr5_+_138171997 1.23 ENSMUST00000019662.4
ENSMUST00000151318.1
adaptor-related protein complex AP-4, mu 1
chr13_-_47106176 1.19 ENSMUST00000021807.6
ENSMUST00000135278.1
DEK oncogene (DNA binding)
chr1_+_181150926 1.19 ENSMUST00000134115.1
ENSMUST00000111059.1
cornichon homolog 4 (Drosophila)
chr5_-_136135989 1.18 ENSMUST00000150406.1
ENSMUST00000006301.4
leucine-rich repeats and WD repeat domain containing 1
chr9_-_21291124 1.17 ENSMUST00000086374.6
cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
chr19_+_46075842 1.16 ENSMUST00000165017.1
nucleolar and coiled-body phosphoprotein 1
chrX_+_135885851 1.15 ENSMUST00000180025.1
ENSMUST00000068755.7
ENSMUST00000148374.1
basic helix-loop-helix domain containing, class B9
chr16_-_18248697 1.15 ENSMUST00000115645.3
RAN binding protein 1
chr16_-_5255923 1.14 ENSMUST00000139584.1
ENSMUST00000064635.5
family with sequence similarity 86
chr6_+_14901344 1.12 ENSMUST00000115477.1
forkhead box P2
chr3_+_10088173 1.10 ENSMUST00000061419.7
predicted gene 9833
chr1_-_191183244 1.10 ENSMUST00000027941.8
activating transcription factor 3
chr13_-_63431737 1.09 ENSMUST00000073029.5
Fanconi anemia, complementation group C
chr8_+_55940453 1.08 ENSMUST00000000275.7
glycine receptor, alpha 3 subunit
chr16_-_45742888 1.07 ENSMUST00000128348.1
ENSMUST00000066983.6
abhydrolase domain containing 10
chr4_+_32615473 1.07 ENSMUST00000178925.1
ENSMUST00000029950.3
caspase 8 associated protein 2
chr15_-_55557748 1.04 ENSMUST00000172387.1
mitochondrial ribosomal protein L13
chr16_-_76373827 1.04 ENSMUST00000121927.1
nuclear receptor interacting protein 1
chr16_-_18876655 1.03 ENSMUST00000023391.8
mitochondrial ribosomal protein L40
chr10_-_21160925 1.03 ENSMUST00000020158.6
myeloblastosis oncogene
chr18_+_31789120 1.02 ENSMUST00000025106.3
polymerase (RNA) II (DNA directed) polypeptide D
chr7_-_122101735 1.02 ENSMUST00000139456.1
ENSMUST00000106471.2
ENSMUST00000123296.1
ENSMUST00000033157.3
NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1
chr11_-_6444352 1.01 ENSMUST00000093346.5
ENSMUST00000109737.2
H2A histone family, member V
chr19_-_5457397 1.00 ENSMUST00000179549.1
coiled-coil domain containing 85B
chr1_-_38129618 0.98 ENSMUST00000027251.6
REV1 homolog (S. cerevisiae)
chr11_+_87405049 0.97 ENSMUST00000060835.5
testis expressed gene 14
chr2_-_157204483 0.97 ENSMUST00000029170.7
retinoblastoma-like 1 (p107)
chr11_-_87404380 0.95 ENSMUST00000067692.6
RAD51 homolog C
chr9_-_21091974 0.94 ENSMUST00000115487.1
ribonucleoprotein, PTB-binding 1
chrX_+_68678541 0.93 ENSMUST00000088546.5
fragile X mental retardation syndrome 1
chr12_+_112644828 0.93 ENSMUST00000021728.4
ENSMUST00000109755.3
SIVA1, apoptosis-inducing factor
chr2_-_152398046 0.90 ENSMUST00000063332.8
ENSMUST00000182625.1
SRY-box containing gene 12
chr11_+_50602072 0.90 ENSMUST00000040523.8
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 2
chr7_+_82867327 0.90 ENSMUST00000082237.5
mex3 homolog B (C. elegans)
chr4_+_109280365 0.89 ENSMUST00000177089.1
ENSMUST00000175776.1
ENSMUST00000132165.2
epidermal growth factor receptor pathway substrate 15
chr5_-_110839575 0.89 ENSMUST00000145318.1
HscB iron-sulfur cluster co-chaperone homolog (E. coli)
chr1_+_86526688 0.88 ENSMUST00000045897.8
prothymosin alpha
chr2_-_34799618 0.88 ENSMUST00000113086.2
ENSMUST00000118108.1
Rab9 effector protein with kelch motifs
chr13_+_100108155 0.87 ENSMUST00000129014.1
small EDRK-rich factor 1
chr5_-_110286159 0.86 ENSMUST00000031472.5
peroxisomal membrane protein 2
chr10_-_128960965 0.85 ENSMUST00000026398.3
methyltransferase like 7B
chr15_+_9140527 0.85 ENSMUST00000090380.4
LMBR1 domain containing 2
chr5_-_24030297 0.84 ENSMUST00000101513.2
family with sequence similarity 126, member A
chr7_-_45395672 0.84 ENSMUST00000074575.7
small nuclear ribonucleoprotein 70 (U1)
chr11_+_69935796 0.83 ENSMUST00000018698.5
Y box protein 2
chr10_-_7956223 0.82 ENSMUST00000146444.1
TGF-beta activated kinase 1/MAP3K7 binding protein 2
chr9_+_109875541 0.81 ENSMUST00000094324.3
cell division cycle 25A

Network of associatons between targets according to the STRING database.

First level regulatory network of E2f2_E2f5

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
9.3 28.0 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
5.2 5.2 GO:0045004 DNA replication proofreading(GO:0045004)
4.6 18.4 GO:0006272 leading strand elongation(GO:0006272)
4.3 43.3 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
2.9 8.6 GO:0035622 intrahepatic bile duct development(GO:0035622) cholangiocyte proliferation(GO:1990705)
2.8 30.8 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
2.2 22.1 GO:1902969 mitotic DNA replication(GO:1902969)
2.0 8.0 GO:0007056 spindle assembly involved in female meiosis(GO:0007056)
2.0 17.6 GO:0090166 Golgi disassembly(GO:0090166)
1.9 9.7 GO:0034421 post-translational protein acetylation(GO:0034421)
1.9 11.6 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
1.9 13.1 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
1.8 7.1 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
1.7 20.0 GO:0090308 regulation of methylation-dependent chromatin silencing(GO:0090308)
1.6 40.1 GO:0006270 DNA replication initiation(GO:0006270)
1.6 1.6 GO:0009211 pyrimidine deoxyribonucleoside triphosphate metabolic process(GO:0009211)
1.5 10.5 GO:0070495 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
1.4 16.8 GO:0033504 floor plate development(GO:0033504)
1.1 5.6 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
1.0 1.0 GO:0031990 mRNA export from nucleus in response to heat stress(GO:0031990)
1.0 11.9 GO:0019985 translesion synthesis(GO:0019985)
1.0 2.9 GO:1904976 response to bleomycin(GO:1904975) cellular response to bleomycin(GO:1904976)
1.0 8.6 GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.9 5.5 GO:0046654 tetrahydrofolate biosynthetic process(GO:0046654)
0.8 15.2 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.8 6.5 GO:2000232 regulation of rRNA processing(GO:2000232)
0.8 2.4 GO:0071707 immunoglobulin heavy chain V-D-J recombination(GO:0071707)
0.8 2.4 GO:1904349 positive regulation of small intestine smooth muscle contraction(GO:1904349)
0.8 6.3 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.8 3.1 GO:0000076 DNA replication checkpoint(GO:0000076)
0.8 0.8 GO:0060382 regulation of DNA strand elongation(GO:0060382)
0.7 2.9 GO:0046125 pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.7 7.0 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.7 2.0 GO:0031662 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662)
0.6 6.1 GO:0000212 meiotic spindle organization(GO:0000212)
0.5 1.6 GO:0099578 regulation of translation at synapse, modulating synaptic transmission(GO:0099547) regulation of translation at postsynapse, modulating synaptic transmission(GO:0099578) positive regulation of intracellular transport of viral material(GO:1901254)
0.5 1.6 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228)
0.5 2.4 GO:0043137 DNA replication, Okazaki fragment processing(GO:0033567) DNA replication, removal of RNA primer(GO:0043137)
0.5 5.2 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.5 3.7 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.5 1.4 GO:0071929 alpha-tubulin acetylation(GO:0071929)
0.5 6.0 GO:1903818 positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.5 2.3 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)
0.5 7.3 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.4 2.2 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.4 5.2 GO:0023035 CD40 signaling pathway(GO:0023035)
0.4 1.3 GO:0060821 inactivation of X chromosome by DNA methylation(GO:0060821)
0.4 4.1 GO:0036123 histone H3-K9 dimethylation(GO:0036123)
0.4 2.0 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.4 2.0 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.4 2.3 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.4 3.7 GO:0015727 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.4 5.6 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.4 1.1 GO:1903984 positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.4 1.1 GO:0035607 orbitofrontal cortex development(GO:0021769) fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604) fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development(GO:0035607) coronal suture morphogenesis(GO:0060365)
0.4 2.2 GO:0021631 optic nerve morphogenesis(GO:0021631)
0.4 1.1 GO:0019389 glucuronoside metabolic process(GO:0019389)
0.3 1.3 GO:0099527 postsynapse to nucleus signaling pathway(GO:0099527)
0.3 12.3 GO:0006284 base-excision repair(GO:0006284)
0.3 2.7 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.3 2.4 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.3 1.2 GO:0071169 establishment of protein localization to chromatin(GO:0071169)
0.3 4.7 GO:1904816 positive regulation of protein localization to chromosome, telomeric region(GO:1904816)
0.3 16.9 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.3 0.8 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.3 1.0 GO:0001543 ovarian follicle rupture(GO:0001543)
0.2 1.0 GO:0032466 negative regulation of cytokinesis(GO:0032466)
0.2 1.4 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.2 1.3 GO:2000304 chondroblast differentiation(GO:0060591) positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.2 1.2 GO:0000731 DNA synthesis involved in DNA repair(GO:0000731)
0.2 0.6 GO:1903438 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
0.2 1.5 GO:0008215 spermine metabolic process(GO:0008215)
0.2 0.7 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.2 1.2 GO:2001032 cell quiescence(GO:0044838) regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.2 2.6 GO:0006895 Golgi to endosome transport(GO:0006895)
0.2 1.1 GO:0036337 Fas signaling pathway(GO:0036337)
0.1 1.5 GO:0042984 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.1 0.4 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.1 5.0 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.1 0.4 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.1 1.8 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.1 1.2 GO:0007000 nucleolus organization(GO:0007000)
0.1 0.9 GO:0072697 protein localization to cell cortex(GO:0072697)
0.1 1.0 GO:0009249 protein lipoylation(GO:0009249)
0.1 2.8 GO:0009303 rRNA transcription(GO:0009303)
0.1 1.2 GO:0006020 inositol metabolic process(GO:0006020)
0.1 1.3 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.1 1.3 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.1 0.4 GO:1901896 protein localization to nuclear pore(GO:0090204) positive regulation of calcium-transporting ATPase activity(GO:1901896)
0.1 1.1 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.1 1.4 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.1 3.2 GO:0007099 centriole replication(GO:0007099)
0.1 2.3 GO:0002347 response to tumor cell(GO:0002347)
0.1 2.1 GO:0032098 regulation of appetite(GO:0032098)
0.1 0.5 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 0.6 GO:0061622 glycolytic process through glucose-1-phosphate(GO:0061622)
0.1 1.9 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.1 0.4 GO:0033092 positive regulation of immature T cell proliferation in thymus(GO:0033092)
0.1 0.4 GO:0003349 epicardium-derived cardiac endothelial cell differentiation(GO:0003349)
0.1 0.8 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.1 1.0 GO:0051571 positive regulation of histone H3-K4 methylation(GO:0051571)
0.1 6.7 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512)
0.1 0.3 GO:1903630 regulation of aminoacyl-tRNA ligase activity(GO:1903630) positive regulation of aminoacyl-tRNA ligase activity(GO:1903632)
0.1 0.2 GO:0086047 membrane depolarization during Purkinje myocyte cell action potential(GO:0086047)
0.1 1.0 GO:0008063 Toll signaling pathway(GO:0008063)
0.1 0.2 GO:0033484 nitric oxide homeostasis(GO:0033484)
0.1 0.9 GO:1901030 positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901030)
0.1 1.4 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.1 0.3 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.1 1.8 GO:0034453 microtubule anchoring(GO:0034453)
0.1 0.7 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.1 1.8 GO:0019430 removal of superoxide radicals(GO:0019430)
0.1 0.6 GO:0035562 negative regulation of chromatin binding(GO:0035562)
0.1 1.8 GO:0021511 spinal cord patterning(GO:0021511)
0.1 1.9 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.1 0.4 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.1 0.4 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.1 1.9 GO:0040034 regulation of development, heterochronic(GO:0040034)
0.1 0.2 GO:0016240 autophagosome docking(GO:0016240)
0.1 0.5 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.1 0.6 GO:0018095 protein polyglutamylation(GO:0018095)
0.1 1.4 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1 0.4 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.1 0.2 GO:0035928 rRNA import into mitochondrion(GO:0035928)
0.0 0.2 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.0 0.5 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.0 0.2 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 0.7 GO:0060134 prepulse inhibition(GO:0060134)
0.0 0.9 GO:0043486 histone exchange(GO:0043486)
0.0 1.0 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.0 1.4 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.3 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.9 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.8 GO:1902751 positive regulation of cell cycle G2/M phase transition(GO:1902751)
0.0 0.3 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.0 0.1 GO:0034088 maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.0 9.2 GO:0007018 microtubule-based movement(GO:0007018)
0.0 1.1 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.0 0.1 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.0 0.3 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 0.2 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.4 GO:0042532 negative regulation of tyrosine phosphorylation of STAT protein(GO:0042532)
0.0 0.1 GO:0046607 positive regulation of centrosome duplication(GO:0010825) positive regulation of centrosome cycle(GO:0046607)
0.0 1.6 GO:0001541 ovarian follicle development(GO:0001541)
0.0 0.4 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.0 0.2 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 1.0 GO:0032781 positive regulation of ATPase activity(GO:0032781)
0.0 1.0 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.0 0.1 GO:1901844 regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844)
0.0 2.5 GO:0006364 rRNA processing(GO:0006364)
0.0 0.2 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.5 GO:0048255 mRNA stabilization(GO:0048255)
0.0 0.0 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.0 0.9 GO:0021510 spinal cord development(GO:0021510)
0.0 1.2 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.0 0.4 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 2.5 GO:0006836 neurotransmitter transport(GO:0006836)
0.0 0.1 GO:1990035 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.0 0.2 GO:0044804 nucleophagy(GO:0044804)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
4.4 65.6 GO:0042555 MCM complex(GO:0042555)
3.5 10.5 GO:0000811 GINS complex(GO:0000811)
3.0 15.2 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
2.5 12.5 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
2.2 11.2 GO:0031298 replication fork protection complex(GO:0031298)
1.8 8.8 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
1.7 5.2 GO:0043625 delta DNA polymerase complex(GO:0043625)
1.3 6.5 GO:0001651 dense fibrillar component(GO:0001651)
1.1 9.7 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.9 4.6 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.9 2.7 GO:0035061 interchromatin granule(GO:0035061)
0.9 7.7 GO:0032300 mismatch repair complex(GO:0032300)
0.8 6.6 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.8 4.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.7 2.2 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
0.7 38.0 GO:0005657 replication fork(GO:0005657)
0.6 5.8 GO:0000796 condensin complex(GO:0000796)
0.5 7.5 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.5 5.8 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.5 2.3 GO:0035189 Rb-E2F complex(GO:0035189)
0.5 0.5 GO:0030893 meiotic cohesin complex(GO:0030893)
0.4 2.6 GO:0098536 deuterosome(GO:0098536)
0.4 2.6 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.4 1.6 GO:0019034 viral replication complex(GO:0019034) dendritic filopodium(GO:1902737)
0.3 19.6 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.3 2.3 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.3 1.6 GO:0044611 nuclear pore inner ring(GO:0044611)
0.3 8.5 GO:0000800 lateral element(GO:0000800)
0.3 2.9 GO:0001673 male germ cell nucleus(GO:0001673)
0.3 2.0 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.3 2.0 GO:0005638 lamin filament(GO:0005638)
0.3 0.8 GO:0018444 translation release factor complex(GO:0018444)
0.3 1.3 GO:0001740 Barr body(GO:0001740)
0.2 1.0 GO:1903349 omegasome membrane(GO:1903349)
0.2 1.1 GO:0034709 methylosome(GO:0034709)
0.2 5.5 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.2 14.1 GO:0005871 kinesin complex(GO:0005871)
0.2 1.3 GO:0005827 polar microtubule(GO:0005827)
0.2 30.8 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.2 2.0 GO:0031080 nuclear pore outer ring(GO:0031080)
0.2 1.3 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.2 2.8 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.2 1.2 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.2 0.6 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.2 3.8 GO:0071565 nBAF complex(GO:0071565)
0.1 6.4 GO:0032590 dendrite membrane(GO:0032590)
0.1 2.4 GO:0016580 Sin3 complex(GO:0016580)
0.1 0.5 GO:0070822 Sin3-type complex(GO:0070822)
0.1 14.2 GO:0005814 centriole(GO:0005814)
0.1 0.7 GO:0044530 supraspliceosomal complex(GO:0044530)
0.1 0.4 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.1 1.8 GO:0051233 spindle midzone(GO:0051233)
0.1 0.8 GO:0000243 commitment complex(GO:0000243)
0.1 1.4 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.1 1.5 GO:0070938 contractile ring(GO:0070938)
0.1 1.1 GO:1904115 axon cytoplasm(GO:1904115)
0.1 5.3 GO:0072686 mitotic spindle(GO:0072686)
0.1 2.4 GO:0035145 exon-exon junction complex(GO:0035145)
0.1 0.4 GO:0000801 central element(GO:0000801)
0.1 1.0 GO:0035631 CD40 receptor complex(GO:0035631)
0.1 1.2 GO:0030131 clathrin adaptor complex(GO:0030131)
0.1 5.3 GO:0016605 PML body(GO:0016605)
0.1 1.2 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.1 0.7 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.1 3.8 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 7.5 GO:0005819 spindle(GO:0005819)
0.1 2.9 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1 1.3 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 2.3 GO:0005801 cis-Golgi network(GO:0005801)
0.0 1.8 GO:0030686 90S preribosome(GO:0030686)
0.0 3.6 GO:0000776 kinetochore(GO:0000776)
0.0 0.7 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 1.9 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 10.6 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.5 GO:0097470 ribbon synapse(GO:0097470)
0.0 1.0 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 1.2 GO:0015030 Cajal body(GO:0015030)
0.0 0.5 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.6 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.9 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.0 0.3 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.2 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.3 GO:0032433 filopodium tip(GO:0032433)
0.0 7.4 GO:0005813 centrosome(GO:0005813)
0.0 2.3 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 1.1 GO:0034707 chloride channel complex(GO:0034707)
0.0 2.2 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 1.9 GO:0043195 terminal bouton(GO:0043195)
0.0 0.1 GO:0031251 PAN complex(GO:0031251)
0.0 0.3 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 5.7 GO:0043235 receptor complex(GO:0043235)
0.0 0.4 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.2 GO:0044754 autolysosome(GO:0044754)
0.0 0.7 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.8 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.1 GO:0061617 MICOS complex(GO:0061617)
0.0 0.2 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.2 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.5 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 1.3 GO:0043197 dendritic spine(GO:0043197)
0.0 14.6 GO:0005794 Golgi apparatus(GO:0005794)
0.0 0.1 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.1 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
4.6 27.9 GO:0010997 anaphase-promoting complex binding(GO:0010997)
3.3 20.0 GO:0031493 nucleosomal histone binding(GO:0031493)
3.0 15.2 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
2.0 28.6 GO:0003688 DNA replication origin binding(GO:0003688)
1.9 5.6 GO:0032139 dinucleotide insertion or deletion binding(GO:0032139)
1.6 3.3 GO:0032138 DNA insertion or deletion binding(GO:0032135) single base insertion or deletion binding(GO:0032138)
1.5 5.9 GO:0048256 flap endonuclease activity(GO:0048256)
1.5 8.9 GO:0044547 DNA topoisomerase binding(GO:0044547)
1.2 6.1 GO:0000150 recombinase activity(GO:0000150)
1.2 9.5 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
1.1 19.3 GO:0035173 histone kinase activity(GO:0035173)
1.1 5.3 GO:0000405 bubble DNA binding(GO:0000405)
1.0 29.7 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.9 26.6 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.9 8.0 GO:0055104 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.9 7.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.9 9.7 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.9 10.5 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.8 4.1 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.7 2.9 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.7 4.7 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.6 5.8 GO:1990446 U1 snRNP binding(GO:1990446)
0.6 0.6 GO:0009008 DNA-methyltransferase activity(GO:0009008)
0.6 0.6 GO:0032137 guanine/thymine mispair binding(GO:0032137)
0.5 2.2 GO:0036033 mediator complex binding(GO:0036033)
0.5 3.7 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.5 5.5 GO:0051870 methotrexate binding(GO:0051870)
0.4 5.6 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.4 2.2 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.4 1.4 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.4 1.4 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.3 8.2 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.3 2.0 GO:0097016 L27 domain binding(GO:0097016)
0.3 5.3 GO:1990226 histone methyltransferase binding(GO:1990226)
0.3 2.0 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.3 2.6 GO:0034511 U3 snoRNA binding(GO:0034511)
0.3 4.2 GO:0043047 single-stranded telomeric DNA binding(GO:0043047) G-rich strand telomeric DNA binding(GO:0098505)
0.3 2.0 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.3 6.1 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.3 2.7 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.3 2.4 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.3 2.4 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.3 5.2 GO:0070182 DNA polymerase binding(GO:0070182)
0.3 2.3 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.2 0.7 GO:0015275 stretch-activated, cation-selective, calcium channel activity(GO:0015275)
0.2 8.6 GO:0051059 NF-kappaB binding(GO:0051059)
0.2 44.2 GO:0003714 transcription corepressor activity(GO:0003714)
0.2 0.5 GO:0000402 open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402)
0.2 1.6 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.2 5.7 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.2 0.7 GO:0097506 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.2 0.6 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.1 4.4 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.1 14.1 GO:0003777 microtubule motor activity(GO:0003777)
0.1 1.1 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.1 8.2 GO:0035064 methylated histone binding(GO:0035064)
0.1 1.3 GO:0004526 ribonuclease P activity(GO:0004526)
0.1 1.2 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.1 14.9 GO:0004386 helicase activity(GO:0004386)
0.1 0.6 GO:0051425 PTB domain binding(GO:0051425)
0.1 0.7 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1 0.3 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.1 0.8 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.1 2.0 GO:0008432 JUN kinase binding(GO:0008432)
0.1 2.1 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 0.4 GO:0051525 NFAT protein binding(GO:0051525)
0.1 0.2 GO:0016748 succinyltransferase activity(GO:0016748)
0.1 0.3 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.1 4.4 GO:0003697 single-stranded DNA binding(GO:0003697)
0.1 0.3 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) chondroitin sulfotransferase activity(GO:0034481)
0.1 0.7 GO:0001055 RNA polymerase II activity(GO:0001055)
0.1 0.7 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.1 18.4 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.1 1.6 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 0.6 GO:0070739 protein-glutamic acid ligase activity(GO:0070739)
0.1 2.3 GO:0001671 ATPase activator activity(GO:0001671)
0.1 1.4 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 0.5 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 0.3 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.1 4.7 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.1 2.0 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.1 1.9 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.7 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 17.4 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.9 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.4 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.9 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 0.4 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 1.4 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.7 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 1.7 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.4 GO:0044388 small protein activating enzyme binding(GO:0044388)
0.0 5.5 GO:0001047 core promoter binding(GO:0001047)
0.0 0.2 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0 0.2 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.1 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 1.5 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0 2.9 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 1.5 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 1.0 GO:0072341 modified amino acid binding(GO:0072341)
0.0 1.2 GO:0042393 histone binding(GO:0042393)
0.0 3.4 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 0.2 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 19.6 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
1.7 77.8 PID ATR PATHWAY ATR signaling pathway
1.2 17.4 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.7 59.8 PID E2F PATHWAY E2F transcription factor network
0.5 16.8 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.4 17.0 PID AURORA B PATHWAY Aurora B signaling
0.4 9.4 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.3 28.9 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.2 6.3 PID BARD1 PATHWAY BARD1 signaling events
0.2 9.4 PID PLK1 PATHWAY PLK1 signaling events
0.2 11.6 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.1 10.0 PID NOTCH PATHWAY Notch signaling pathway
0.1 1.5 ST JAK STAT PATHWAY Jak-STAT Pathway
0.1 3.8 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1 1.6 PID ATM PATHWAY ATM pathway
0.1 1.1 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1 2.9 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.1 1.3 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 3.9 PID CMYB PATHWAY C-MYB transcription factor network
0.0 1.7 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.4 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 1.0 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 1.0 PID CD40 PATHWAY CD40/CD40L signaling
0.0 1.4 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 2.0 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 1.0 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.4 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 1.1 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 1.2 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 0.8 PID P73PATHWAY p73 transcription factor network
0.0 0.8 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.3 PID EPHRINB REV PATHWAY Ephrin B reverse signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
5.1 81.1 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
3.5 63.4 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
2.3 25.5 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
1.7 15.4 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
1.3 9.3 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
1.1 4.2 REACTOME DNA STRAND ELONGATION Genes involved in DNA strand elongation
0.8 8.6 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.6 3.8 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.6 5.2 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.5 6.4 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.5 13.8 REACTOME KINESINS Genes involved in Kinesins
0.5 3.0 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.4 4.4 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.4 4.7 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.2 2.7 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.2 7.4 REACTOME G1 PHASE Genes involved in G1 Phase
0.2 9.0 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.2 1.3 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.2 2.9 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 1.5 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.1 4.1 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.1 1.4 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.1 5.6 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 2.7 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 1.4 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 1.5 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.1 2.4 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.1 18.6 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.1 1.0 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.1 2.3 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 1.1 REACTOME FGFR2C LIGAND BINDING AND ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.0 0.4 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 2.3 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 1.1 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 1.1 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 1.4 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 3.4 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.0 0.5 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.4 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.5 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.7 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 1.3 REACTOME LATE PHASE OF HIV LIFE CYCLE Genes involved in Late Phase of HIV Life Cycle
0.0 0.4 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 1.2 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 1.3 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.7 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.2 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.6 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 2.1 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.9 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.1 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.2 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions