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12D miR HR13_24

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Results for Ppard

Z-value: 0.68

Motif logo

Transcription factors associated with Ppard

Gene Symbol Gene ID Gene Info
ENSMUSG00000002250.9 peroxisome proliferator activator receptor delta

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Ppardmm10_v2_chr17_+_28272191_28272205-0.481.4e-01Click!

Activity profile of Ppard motif

Sorted Z-values of Ppard motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_59484645 1.53 ENSMUST00000028369.5
death associated protein-like 1
chr19_-_7607103 1.37 ENSMUST00000079902.5
ENSMUST00000099729.3
ENSMUST00000159983.1
lectin, galactose binding, soluble 12
chr5_-_131538687 1.05 ENSMUST00000161374.1
autism susceptibility candidate 2
chr1_+_74409376 1.00 ENSMUST00000027366.6
villin 1
chr6_+_78370877 0.92 ENSMUST00000096904.3
regenerating islet-derived 3 beta
chr9_+_108392820 0.79 ENSMUST00000035234.4
RIKEN cDNA 1700102P08 gene
chr4_-_106727930 0.72 ENSMUST00000106770.1
ENSMUST00000145044.1
maestro heat-like repeat family member 7
chr15_+_25773985 0.69 ENSMUST00000125667.1
myosin X
chr2_+_160888101 0.52 ENSMUST00000109455.2
ENSMUST00000040872.6
lipin 3
chr17_+_52602700 0.46 ENSMUST00000039366.10
potassium voltage-gated channel, subfamily H (eag-related), member 8
chr15_-_89425795 0.45 ENSMUST00000168376.1
carnitine palmitoyltransferase 1b, muscle
chr2_+_160888156 0.45 ENSMUST00000109457.2
lipin 3
chr5_+_114146525 0.41 ENSMUST00000102582.1
acetyl-Coenzyme A carboxylase beta
chr19_+_46152505 0.39 ENSMUST00000026254.7
golgi-specific brefeldin A-resistance factor 1
chr9_+_46012810 0.39 ENSMUST00000126865.1
SIK family kinase 3
chr11_-_83592981 0.37 ENSMUST00000019071.3
chemokine (C-C motif) ligand 6
chr9_+_118506226 0.35 ENSMUST00000084820.4
golgi autoantigen, golgin subfamily a, 4
chr4_+_131873608 0.35 ENSMUST00000053819.3
serine/arginine-rich splicing factor 4
chr19_-_32061438 0.34 ENSMUST00000096119.4
N-acylsphingosine amidohydrolase 2
chr3_-_88027465 0.33 ENSMUST00000005014.2
hyaluronan and proteoglycan link protein 2
chr17_-_35910032 0.32 ENSMUST00000141662.1
ENSMUST00000056034.6
ENSMUST00000077494.6
ENSMUST00000149277.1
ENSMUST00000061052.5
alpha tubulin acetyltransferase 1
chr15_+_25940846 0.31 ENSMUST00000110438.1
family with sequence similarity 134, member B
chr17_-_46438471 0.31 ENSMUST00000087012.5
solute carrier family 22 (organic anion transporter), member 7
chr1_-_133690100 0.31 ENSMUST00000169295.1
lymphocyte transmembrane adaptor 1
chr4_-_129440800 0.30 ENSMUST00000053042.5
ENSMUST00000106046.1
zinc finger and BTB domain containing 8b
chr3_-_79628660 0.29 ENSMUST00000120992.1
electron transferring flavoprotein, dehydrogenase
chr3_+_98280427 0.28 ENSMUST00000090746.2
ENSMUST00000120541.1
3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2
chr6_+_125145235 0.28 ENSMUST00000119527.1
ENSMUST00000088276.6
ENSMUST00000051171.7
ENSMUST00000117675.1
intermediate filament family orphan 1
chr4_+_59581645 0.27 ENSMUST00000107528.1
hydroxysteroid dehydrogenase like 2
chr9_-_22002599 0.26 ENSMUST00000115336.2
ENSMUST00000044926.5
coiled-coil domain containing 151
chr10_-_125328957 0.26 ENSMUST00000063318.2
solute carrier family 16 (monocarboxylic acid transporters), member 7
chr5_+_129725063 0.26 ENSMUST00000086046.3
glioblastoma amplified sequence
chr6_+_7844806 0.25 ENSMUST00000040159.4
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1
chr9_+_46012822 0.25 ENSMUST00000120463.2
ENSMUST00000120247.1
SIK family kinase 3
chr4_+_59581563 0.25 ENSMUST00000030078.5
hydroxysteroid dehydrogenase like 2
chr9_+_107340593 0.24 ENSMUST00000042581.2
RIKEN cDNA 6430571L13 gene
chr9_+_22003035 0.24 ENSMUST00000115331.2
ENSMUST00000003493.7
protein kinase C substrate 80K-H
chr3_+_51661167 0.23 ENSMUST00000099106.3
microsomal glutathione S-transferase 2
chr1_+_178319130 0.22 ENSMUST00000027781.6
COX20 Cox2 chaperone
chr7_+_141468776 0.21 ENSMUST00000058746.5
CD151 antigen
chr11_+_70657687 0.21 ENSMUST00000134087.1
ENSMUST00000170716.1
enolase 3, beta muscle
chr9_-_110989611 0.21 ENSMUST00000084922.5
receptor transporter protein 3
chr3_+_139205887 0.19 ENSMUST00000062306.6
sperm tail PG rich repeat containing 2
chr6_+_83156401 0.19 ENSMUST00000032106.4
RIKEN cDNA 1700003E16 gene
chr11_-_73326807 0.19 ENSMUST00000134079.1
aspartoacylase
chr10_-_13324160 0.19 ENSMUST00000105545.4
phosphatase and actin regulator 2
chr18_-_36726730 0.19 ENSMUST00000061829.6
CD14 antigen
chr19_+_4594312 0.19 ENSMUST00000113825.2
pyruvate carboxylase
chr15_-_89425856 0.19 ENSMUST00000109313.2
carnitine palmitoyltransferase 1b, muscle
chr4_+_98546919 0.18 ENSMUST00000030290.7
InaD-like (Drosophila)
chr19_-_45998479 0.18 ENSMUST00000045396.7
RIKEN cDNA 9130011E15 gene
chr14_+_75136475 0.18 ENSMUST00000122840.1
lymphocyte cytosolic protein 1
chr16_-_3907651 0.18 ENSMUST00000177221.1
ENSMUST00000177323.1
RIKEN cDNA 1700037C18 gene
chr12_+_84451485 0.17 ENSMUST00000137170.1
lin-52 homolog (C. elegans)
chr19_-_6921753 0.16 ENSMUST00000173635.1
estrogen related receptor, alpha
chr2_+_92375306 0.15 ENSMUST00000028650.8
peroxisomal biogenesis factor 16
chr17_-_35643684 0.15 ENSMUST00000095467.3
diffuse panbronchiolitis critical region 1 (human)
chr4_-_137048695 0.15 ENSMUST00000049583.7
zinc finger and BTB domain containing 40
chr1_+_74506044 0.15 ENSMUST00000087215.5
rcd1 (required for cell differentiation) homolog 1 (S. pombe)
chr4_+_98546710 0.15 ENSMUST00000102792.3
InaD-like (Drosophila)
chr12_-_40223149 0.15 ENSMUST00000171553.1
ENSMUST00000001672.5
interferon-related developmental regulator 1
chr5_-_31697598 0.14 ENSMUST00000031018.7
ribokinase
chr4_-_41048124 0.14 ENSMUST00000030136.6
aquaporin 7
chr11_-_73326472 0.13 ENSMUST00000155630.2
aspartoacylase
chr11_+_4986824 0.12 ENSMUST00000009234.9
ENSMUST00000109897.1
adaptor protein complex AP-1, beta 1 subunit
chr1_+_55088132 0.12 ENSMUST00000075242.6
heat shock protein 1 (chaperonin 10)
chr2_-_127541412 0.12 ENSMUST00000028855.7
prominin 2
chr3_-_79628859 0.11 ENSMUST00000029386.7
electron transferring flavoprotein, dehydrogenase
chr3_+_139205658 0.11 ENSMUST00000106239.1
sperm tail PG rich repeat containing 2
chr8_+_71469186 0.11 ENSMUST00000124745.1
ENSMUST00000138892.1
ENSMUST00000147642.1
DET1 and DDB1 associated 1
chr5_-_110286159 0.10 ENSMUST00000031472.5
peroxisomal membrane protein 2
chr11_+_98446826 0.10 ENSMUST00000019456.4
growth factor receptor bound protein 7
chr19_-_6921804 0.10 ENSMUST00000025906.4
estrogen related receptor, alpha
chr11_-_94499962 0.09 ENSMUST00000127305.1
epsin 3
chr15_-_50890396 0.09 ENSMUST00000185183.1
trichorhinophalangeal syndrome I (human)
chr4_-_155043143 0.09 ENSMUST00000135665.2
phospholipase C, eta 2
chr13_+_23782572 0.09 ENSMUST00000074067.2
tripartite motif-containing 38
chr3_+_90051630 0.08 ENSMUST00000159064.1
RIKEN cDNA 4933434E20 gene
chr19_+_4139799 0.07 ENSMUST00000096338.3
G protein-coupled receptor 152
chr2_-_26237368 0.07 ENSMUST00000036187.8
quiescin Q6 sulfhydryl oxidase 2
chr2_+_165992625 0.07 ENSMUST00000109252.1
ENSMUST00000088095.5
nuclear receptor coactivator 3
chr7_+_43444104 0.06 ENSMUST00000004729.3
electron transferring flavoprotein, beta polypeptide
chr5_+_31698050 0.06 ENSMUST00000114507.3
ENSMUST00000063813.4
ENSMUST00000071531.5
ENSMUST00000131995.1
brain and reproductive organ-expressed protein
chr10_+_58255465 0.06 ENSMUST00000057659.7
ENSMUST00000162041.1
ENSMUST00000162860.1
GRIP and coiled-coil domain containing 2
chr15_-_27630644 0.05 ENSMUST00000059662.7
family with sequence similarity 105, member B
chr15_-_102189032 0.04 ENSMUST00000023805.1
cysteine sulfinic acid decarboxylase
chrX_+_10252361 0.04 ENSMUST00000115528.2
ornithine transcarbamylase
chr1_+_82724909 0.04 ENSMUST00000073025.5
ENSMUST00000161648.1
ENSMUST00000160786.1
ENSMUST00000162003.1
mitochondrial fission factor
chr14_-_8258800 0.03 ENSMUST00000022271.7
acyl-Coenzyme A oxidase 2, branched chain
chr3_-_8923796 0.03 ENSMUST00000042148.5
mitochondrial ribosomal protein S28
chr19_+_5460607 0.03 ENSMUST00000025847.5
fibroblast growth factor (acidic) intracellular binding protein
chr6_-_142473075 0.02 ENSMUST00000032371.7
glycogen synthase 2
chr19_+_5704367 0.02 ENSMUST00000052448.3
potassium channel, subfamily K, member 7
chr1_-_124045247 0.02 ENSMUST00000112603.2
dipeptidylpeptidase 10
chr5_+_31697960 0.02 ENSMUST00000114515.2
brain and reproductive organ-expressed protein
chr7_-_89338709 0.02 ENSMUST00000137723.1
ENSMUST00000117852.1
ENSMUST00000041968.3
transmembrane protein 135
chr10_+_70868633 0.01 ENSMUST00000058942.5
RIKEN cDNA 4930533K18 gene
chr2_+_154436437 0.01 ENSMUST00000109725.1
ENSMUST00000099178.3
ENSMUST00000045270.8
ENSMUST00000109724.1
core-binding factor, runt domain, alpha subunit 2, translocated to, 2 (human)
chr14_+_75136326 0.01 ENSMUST00000145303.1
lymphocyte cytosolic protein 1
chr1_+_171559186 0.00 ENSMUST00000004829.7
CD244 natural killer cell receptor 2B4

Network of associatons between targets according to the STRING database.

First level regulatory network of Ppard

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.3 1.0 GO:1902896 terminal web assembly(GO:1902896)
0.1 0.4 GO:0046949 fatty-acyl-CoA biosynthetic process(GO:0046949) malonyl-CoA metabolic process(GO:2001293)
0.1 0.4 GO:0035964 COPI-coated vesicle budding(GO:0035964) protein localization to endoplasmic reticulum exit site(GO:0070973)
0.1 0.9 GO:1903208 neuron death in response to hydrogen peroxide(GO:0036476) regulation of hydrogen peroxide-induced neuron death(GO:1903207) negative regulation of hydrogen peroxide-induced neuron death(GO:1903208)
0.1 0.3 GO:0071929 alpha-tubulin acetylation(GO:0071929)
0.1 0.5 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.1 0.3 GO:1901475 pyruvate transmembrane transport(GO:1901475)
0.1 0.2 GO:0071727 response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.1 0.2 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.1 0.3 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.1 0.3 GO:0006083 acetate metabolic process(GO:0006083)
0.0 0.1 GO:0006014 D-ribose metabolic process(GO:0006014)
0.0 0.2 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.1 GO:0015793 glycerol transport(GO:0015793)
0.0 0.1 GO:2001287 negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.0 1.5 GO:0034198 cellular response to amino acid starvation(GO:0034198)
0.0 0.2 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.0 0.3 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.3 GO:0035634 response to stilbenoid(GO:0035634) response to phenylpropanoid(GO:0080184)
0.0 0.3 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.0 GO:0019448 cysteine catabolic process(GO:0009093) L-cysteine catabolic process(GO:0019448) L-cysteine metabolic process(GO:0046439)
0.0 0.6 GO:0060351 cartilage development involved in endochondral bone morphogenesis(GO:0060351)
0.0 0.2 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.2 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.2 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.3 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0 0.2 GO:0019370 leukotriene biosynthetic process(GO:0019370)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0045251 mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
0.0 1.0 GO:0032433 filopodium tip(GO:0032433)
0.0 0.2 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.3 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.1 GO:0044393 microspike(GO:0044393)
0.0 0.2 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.5 GO:0042588 zymogen granule(GO:0042588)
0.0 0.2 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0048030 disaccharide binding(GO:0048030)
0.2 1.0 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 0.6 GO:0016416 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.1 1.0 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.1 0.3 GO:0019807 aspartoacylase activity(GO:0019807)
0.1 1.5 GO:0070513 death domain binding(GO:0070513)
0.1 0.4 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.1 0.4 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.1 0.5 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.1 0.2 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.1 0.3 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.1 0.2 GO:0009374 biotin binding(GO:0009374)
0.1 0.3 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.3 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.3 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.2 GO:0031849 olfactory receptor binding(GO:0031849)
0.0 0.2 GO:0071723 lipopeptide binding(GO:0071723)
0.0 0.1 GO:0015254 glycerol channel activity(GO:0015254)
0.0 0.3 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.1 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.0 0.2 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.2 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.0 0.1 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0 0.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.4 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.3 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.4 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.7 GO:0030507 spectrin binding(GO:0030507)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 PID ARF 3PATHWAY Arf1 pathway
0.0 0.7 PID NETRIN PATHWAY Netrin-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 1.1 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.3 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.4 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.2 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.2 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.1 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.7 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling