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12D miR HR13_24

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Results for Pax8

Z-value: 0.26

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Transcription factors associated with Pax8

Gene Symbol Gene ID Gene Info
ENSMUSG00000026976.9 paired box 8

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Pax8mm10_v2_chr2_-_24475596_24475605-0.451.6e-01Click!

Activity profile of Pax8 motif

Sorted Z-values of Pax8 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_30861470 0.36 ENSMUST00000052700.3
free fatty acid receptor 1
chr1_+_150100093 0.26 ENSMUST00000035065.7
prostaglandin-endoperoxide synthase 2
chr12_-_20900867 0.23 ENSMUST00000079237.5
zinc finger protein 125
chrX_-_105391726 0.20 ENSMUST00000142109.1
RIKEN cDNA 5330434G04 gene
chrX_-_105391770 0.19 ENSMUST00000136406.1
ENSMUST00000150604.1
RIKEN cDNA 5330434G04 gene
chr7_-_141100526 0.17 ENSMUST00000097958.2
single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
chr6_+_139736895 0.15 ENSMUST00000111868.3
phosphatidylinositol 3-kinase, C2 domain containing, gamma polypeptide
chr6_+_30610984 0.15 ENSMUST00000062758.4
carboxypeptidase A5
chr13_+_108214389 0.13 ENSMUST00000022207.8
ELOVL family member 7, elongation of long chain fatty acids (yeast)
chr6_+_30611029 0.12 ENSMUST00000115138.1
carboxypeptidase A5
chr8_+_60655540 0.11 ENSMUST00000034066.3
microfibrillar-associated protein 3-like
chr15_-_101869695 0.10 ENSMUST00000087996.5
keratin 77
chr17_+_45555693 0.10 ENSMUST00000024742.7
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, epsilon
chr17_+_21691860 0.10 ENSMUST00000072133.4
predicted gene 10226
chr13_-_62520451 0.10 ENSMUST00000082203.6
ENSMUST00000101547.4
zinc finger protein 934
chr5_+_91074611 0.09 ENSMUST00000031324.4
epiregulin
chrX_-_7572843 0.09 ENSMUST00000132788.1
protein phosphatase 1, regulatory (inhibitor) subunit 3F
chr4_-_43429071 0.08 ENSMUST00000107929.3
ENSMUST00000107928.2
family with sequence similarity 166, member B
chr10_+_116966274 0.08 ENSMUST00000033651.3
RIKEN cDNA D630029K05 gene
chr18_-_12121460 0.07 ENSMUST00000055447.6
ENSMUST00000050228.7
ENSMUST00000092075.4
transmembrane protein 241
chr1_+_165763746 0.06 ENSMUST00000111432.3
cellular repressor of E1A-stimulated genes 1
chr9_-_103230262 0.06 ENSMUST00000165296.1
ENSMUST00000112645.1
ENSMUST00000166836.1
transferrin
predicted gene 20425
chr13_-_62607499 0.06 ENSMUST00000091563.4
RIKEN cDNA 6720489N17 gene
chr7_-_29906087 0.06 ENSMUST00000053521.8
zinc finger protein 27
chr9_+_109052828 0.05 ENSMUST00000124432.1
shisa homolog 5 (Xenopus laevis)
chr7_+_12897800 0.05 ENSMUST00000055528.4
ENSMUST00000117189.1
ENSMUST00000120809.1
ENSMUST00000119989.1
zinc finger and SCAN domain containing 22
chr18_-_66860458 0.05 ENSMUST00000057942.2
melanocortin 4 receptor
chr2_+_143915273 0.05 ENSMUST00000103172.3
destrin
chr12_+_71048338 0.05 ENSMUST00000135709.1
AT rich interactive domain 4A (RBP1-like)
chr4_-_71757965 0.05 ENSMUST00000084489.2
predicted gene 11232
chr6_+_127072902 0.04 ENSMUST00000000186.6
fibroblast growth factor 23
chr9_-_103230415 0.04 ENSMUST00000035158.9
transferrin
chr19_-_11266122 0.04 ENSMUST00000169159.1
membrane-spanning 4-domains, subfamily A, member 1
chr10_+_18845071 0.04 ENSMUST00000019998.7
PERP, TP53 apoptosis effector
chr1_+_65186727 0.02 ENSMUST00000097707.4
ENSMUST00000081154.7
phosphoinositide kinase, FYVE finger containing
chr5_-_117115972 0.02 ENSMUST00000086471.5
ENSMUST00000166397.1
suppressor of defective silencing 3 homolog (S. cerevisiae)
chr8_-_64849818 0.01 ENSMUST00000034017.7
kelch-like 2, Mayven
chr2_-_150255591 0.01 ENSMUST00000063463.5
predicted gene 21994
chrX_+_82948861 0.01 ENSMUST00000114000.1
dystrophin, muscular dystrophy
chr1_+_64690443 0.01 ENSMUST00000114077.1
cyclin Y-like 1
chr13_-_62777089 0.00 ENSMUST00000167516.2
predicted gene 5141

Network of associatons between targets according to the STRING database.

First level regulatory network of Pax8

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.1 0.2 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.0 0.1 GO:0032329 serine transport(GO:0032329)
0.0 0.1 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.0 0.1 GO:0070447 positive regulation of oligodendrocyte progenitor proliferation(GO:0070447)
0.0 0.0 GO:0030043 actin filament fragmentation(GO:0030043)
0.0 0.1 GO:0072530 purine-containing compound transmembrane transport(GO:0072530)
0.0 0.0 GO:0010980 regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.0 0.1 GO:0034626 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0097433 dense body(GO:0097433)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:2001069 glycogen binding(GO:2001069)
0.0 0.0 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0 0.4 GO:0045125 bioactive lipid receptor activity(GO:0045125)
0.0 0.1 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.0 0.1 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.2 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)