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12D miR HR13_24

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Results for Xbp1_Creb3l1

Z-value: 3.40

Motif logo

Transcription factors associated with Xbp1_Creb3l1

Gene Symbol Gene ID Gene Info
ENSMUSG00000020484.12 X-box binding protein 1
ENSMUSG00000027230.9 cAMP responsive element binding protein 3-like 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Creb3l1mm10_v2_chr2_-_92024502_920245290.941.8e-05Click!
Xbp1mm10_v2_chr11_+_5520652_55206590.932.6e-05Click!

Activity profile of Xbp1_Creb3l1 motif

Sorted Z-values of Xbp1_Creb3l1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_+_123267445 6.55 ENSMUST00000047923.7
Sec24 related gene family, member D (S. cerevisiae)
chr3_+_93520473 6.08 ENSMUST00000029515.4
S100 calcium binding protein A11 (calgizzarin)
chr2_+_180725263 6.04 ENSMUST00000094218.3
solute carrier family 17, member 9
chr18_+_57354733 5.76 ENSMUST00000025490.8
proline-rich coiled-coil 1
chr4_-_11386679 5.60 ENSMUST00000043781.7
ENSMUST00000108310.1
epithelial splicing regulatory protein 1
chr4_-_11386757 4.88 ENSMUST00000108313.1
ENSMUST00000108311.2
epithelial splicing regulatory protein 1
chr5_+_92137896 4.69 ENSMUST00000031355.6
USO1 vesicle docking factor
chr3_-_27710413 4.54 ENSMUST00000046157.4
fibronectin type III domain containing 3B
chr15_-_32244632 4.28 ENSMUST00000181536.1
RIKEN cDNA 0610007N19
chr6_+_87042838 4.18 ENSMUST00000113658.1
ENSMUST00000113657.1
ENSMUST00000113655.1
ENSMUST00000032057.7
glutamine fructose-6-phosphate transaminase 1
chr19_+_11965817 4.14 ENSMUST00000025590.9
oxysterol binding protein
chr7_+_35555367 4.06 ENSMUST00000181932.1
RIKEN cDNA B230322F03 gene
chr7_-_45092198 3.89 ENSMUST00000140449.1
ENSMUST00000117546.1
ENSMUST00000019683.3
reticulocalbin 3, EF-hand calcium binding domain
chr11_-_108343917 3.86 ENSMUST00000059595.4
protein kinase C, alpha
chr5_+_113735782 3.81 ENSMUST00000065698.5
FIC domain containing
chr1_-_183369529 3.74 ENSMUST00000069922.5
melanoma inhibitory activity 3
chr7_-_45092130 3.70 ENSMUST00000148175.1
reticulocalbin 3, EF-hand calcium binding domain
chr1_+_157506728 3.69 ENSMUST00000086130.2
SEC16 homolog B (S. cerevisiae)
chr13_-_55415166 3.66 ENSMUST00000054146.3
profilin 3
chr1_+_157506777 3.66 ENSMUST00000027881.8
SEC16 homolog B (S. cerevisiae)
chr9_+_72925622 3.62 ENSMUST00000038489.5
pygopus 1
chr7_-_45091713 3.32 ENSMUST00000141576.1
reticulocalbin 3, EF-hand calcium binding domain
chr15_+_79516396 3.27 ENSMUST00000010974.7
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
chr7_+_116504409 3.23 ENSMUST00000183175.1
nucleobindin 2
chr7_+_116504363 3.22 ENSMUST00000032895.8
nucleobindin 2
chr8_-_106136792 3.20 ENSMUST00000146940.1
epithelial splicing regulatory protein 2
chr13_-_37994111 3.08 ENSMUST00000021864.6
signal sequence receptor, alpha
chr5_+_64970069 3.06 ENSMUST00000031080.8
family with sequence similarity 114, member A1
chr4_-_11386394 2.98 ENSMUST00000155519.1
epithelial splicing regulatory protein 1
chr6_+_88084473 2.84 ENSMUST00000032143.6
ribophorin I
chr8_+_70302518 2.82 ENSMUST00000066469.7
coatomer protein complex, subunit epsilon
chr3_-_97767916 2.82 ENSMUST00000045243.8
phosphodiesterase 4D interacting protein (myomegalin)
chr8_-_106136890 2.80 ENSMUST00000115979.2
epithelial splicing regulatory protein 2
chr2_+_70661556 2.71 ENSMUST00000112201.1
ENSMUST00000028509.4
ENSMUST00000133432.1
ENSMUST00000112205.1
golgi reassembly stacking protein 2
chr12_-_36042476 2.66 ENSMUST00000020896.8
tetraspanin 13
chrX_+_73787002 2.63 ENSMUST00000166518.1
signal sequence receptor, delta
chr5_+_124540695 2.63 ENSMUST00000060226.4
transmembrane emp24 domain trafficking protein 2
chr18_+_51117754 2.61 ENSMUST00000116639.2
proline rich 16
chr5_+_137288273 2.60 ENSMUST00000024099.4
ENSMUST00000085934.3
acetylcholinesterase
chrX_+_73787062 2.59 ENSMUST00000002090.2
signal sequence receptor, delta
chr10_-_128400448 2.58 ENSMUST00000167859.1
solute carrier family 39 (metal ion transporter), member 5
chr8_+_70302761 2.48 ENSMUST00000150968.1
coatomer protein complex, subunit epsilon
chr3_-_108562153 2.26 ENSMUST00000106622.2
transmembrane protein 167B
chr10_+_61680302 2.18 ENSMUST00000020285.8
SAR1 gene homolog A (S. cerevisiae)
chr9_-_104063049 2.18 ENSMUST00000035166.5
ubiquitin-like modifier activating enzyme 5
chr15_-_57892358 2.18 ENSMUST00000022993.5
Der1-like domain family, member 1
chr10_+_41519493 2.17 ENSMUST00000019962.8
CD164 antigen
chr5_+_30869623 2.10 ENSMUST00000114716.1
transmembrane protein 214
chr12_+_13269111 2.09 ENSMUST00000042953.8
neuroblastoma amplified sequence
chr1_-_13589717 2.09 ENSMUST00000027068.4
translocating chain-associating membrane protein 1
chr10_+_42761483 2.03 ENSMUST00000019937.4
SEC63-like (S. cerevisiae)
chr6_-_88518760 2.01 ENSMUST00000032168.5
Sec61 alpha 1 subunit (S. cerevisiae)
chr4_-_114908892 2.01 ENSMUST00000068654.3
forkhead box D2
chr10_+_91083036 1.96 ENSMUST00000020149.5
IKBKB interacting protein
chr9_-_103202113 1.95 ENSMUST00000035157.8
signal recognition particle receptor, B subunit
chr1_-_3671498 1.91 ENSMUST00000070533.4
X Kell blood group precursor related family member 4
chr8_+_25720054 1.90 ENSMUST00000068916.8
ENSMUST00000139836.1
phosphatidic acid phosphatase type 2 domain containing 1B
chr7_-_81992277 1.89 ENSMUST00000026096.7
basonuclin 1
chr5_+_30869579 1.83 ENSMUST00000046349.7
transmembrane protein 214
chr7_+_139212974 1.81 ENSMUST00000016124.8
leucine rich repeat containing 27
chr12_+_33957645 1.80 ENSMUST00000049089.5
twist basic helix-loop-helix transcription factor 1
chr10_+_91082940 1.78 ENSMUST00000020150.3
IKBKB interacting protein
chr11_+_3514861 1.77 ENSMUST00000094469.4
selenoprotein M
chr16_-_11134624 1.76 ENSMUST00000038424.7
thioredoxin domain containing 11
chr3_-_108562349 1.72 ENSMUST00000090546.5
transmembrane protein 167B
chr17_-_34031684 1.70 ENSMUST00000169397.1
solute carrier family 39 (zinc transporter), member 7
chr6_-_4086914 1.69 ENSMUST00000049166.4
blocked early in transport 1 homolog (S. cerevisiae)
chr5_-_115158169 1.68 ENSMUST00000053271.5
ENSMUST00000112121.1
malectin
chr17_-_34031544 1.65 ENSMUST00000025186.8
solute carrier family 39 (zinc transporter), member 7
chr12_+_51377560 1.62 ENSMUST00000021335.5
Sec1 family domain containing 1
chr19_+_5088534 1.62 ENSMUST00000025811.4
Yip1 interacting factor homolog A (S. cerevisiae)
chr4_+_43441939 1.61 ENSMUST00000060864.6
testis specific protein kinase 1
chr4_+_43562672 1.58 ENSMUST00000167751.1
ENSMUST00000132631.1
cAMP responsive element binding protein 3
chr9_+_44379536 1.58 ENSMUST00000161318.1
ENSMUST00000160902.1
hypoxia up-regulated 1
chr3_-_65392579 1.56 ENSMUST00000029414.5
signal sequence receptor, gamma
chr6_+_70844499 1.56 ENSMUST00000034093.8
ENSMUST00000162950.1
eukaryotic translation initiation factor 2 alpha kinase 3
chr16_+_36875119 1.56 ENSMUST00000135406.1
ENSMUST00000114812.1
ENSMUST00000134616.1
ENSMUST00000023534.6
golgi autoantigen, golgin subfamily b, macrogolgin 1
golgi autoantigen, golgin subfamily b, macrogolgin 1
chr3_-_65392546 1.55 ENSMUST00000119896.1
signal sequence receptor, gamma
chr7_+_139213003 1.54 ENSMUST00000156768.1
leucine rich repeat containing 27
chr2_-_144011202 1.51 ENSMUST00000016072.5
ENSMUST00000037875.5
ribosome binding protein 1
chr1_-_93478785 1.51 ENSMUST00000170883.1
high density lipoprotein (HDL) binding protein
chr12_+_59130767 1.50 ENSMUST00000175877.1
CTAGE family, member 5
chr5_+_143403819 1.49 ENSMUST00000110731.2
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
chr15_-_102136225 1.49 ENSMUST00000154032.1
SPRY domain containing 3
chr5_+_124541296 1.47 ENSMUST00000124529.1
transmembrane emp24 domain trafficking protein 2
chr9_+_44379490 1.47 ENSMUST00000066601.6
hypoxia up-regulated 1
chr4_-_129640691 1.46 ENSMUST00000084264.5
taxilin alpha
chr17_-_26199008 1.43 ENSMUST00000142410.1
ENSMUST00000120333.1
ENSMUST00000039113.7
protein disulfide isomerase associated 2
chr3_+_96697100 1.42 ENSMUST00000107077.3
protein inhibitor of activated STAT 3
chr14_+_20674311 1.42 ENSMUST00000048657.8
Sec24 related gene family, member C (S. cerevisiae)
chr17_-_35201996 1.41 ENSMUST00000167924.1
ENSMUST00000025263.8
tumor necrosis factor
chr5_+_144190284 1.39 ENSMUST00000060747.7
basic helix-loop-helix family, member a15
chr10_-_24092320 1.39 ENSMUST00000092654.2
trace amine-associated receptor 8B
chr17_-_34031644 1.38 ENSMUST00000171872.1
solute carrier family 39 (zinc transporter), member 7
chr19_+_8741413 1.37 ENSMUST00000176381.1
syntaxin 5A
chr4_-_118544010 1.35 ENSMUST00000128098.1
transmembrane protein 125
chr16_-_11134601 1.32 ENSMUST00000118362.1
ENSMUST00000118679.1
thioredoxin domain containing 11
chr9_-_44767792 1.32 ENSMUST00000034607.9
archain 1
chr2_-_168742100 1.29 ENSMUST00000109177.1
ATPase, class II, type 9A
chr4_-_132144486 1.27 ENSMUST00000056336.1
opioid receptor, delta 1
chr17_+_29490812 1.25 ENSMUST00000024811.6
proviral integration site 1
chr19_+_8741669 1.25 ENSMUST00000176314.1
ENSMUST00000073430.7
ENSMUST00000175901.1
syntaxin 5A
chr11_+_69095217 1.21 ENSMUST00000101004.2
period circadian clock 1
chr5_+_110176640 1.20 ENSMUST00000112512.1
golgi autoantigen, golgin subfamily a, 3
chr7_-_121035096 1.18 ENSMUST00000065740.2
predicted gene 9905
chr3_+_96697076 1.18 ENSMUST00000162778.2
ENSMUST00000064900.9
protein inhibitor of activated STAT 3
chr19_+_8898090 1.15 ENSMUST00000096246.3
alpha glucosidase 2 alpha neutral subunit
chr1_-_93445642 1.15 ENSMUST00000042498.7
high density lipoprotein (HDL) binding protein
chr11_-_72796028 1.13 ENSMUST00000156294.1
cytochrome b5 domain containing 2
chr16_+_52031549 1.10 ENSMUST00000114471.1
Casitas B-lineage lymphoma b
chr4_+_46489248 1.10 ENSMUST00000030018.4
N-acetylneuraminic acid synthase (sialic acid synthase)
chr8_+_108714644 1.10 ENSMUST00000043896.8
zinc finger homeobox 3
chr11_-_96916448 1.09 ENSMUST00000103152.4
CDK5 regulatory subunit associated protein 3
chr19_+_8741473 1.08 ENSMUST00000177373.1
ENSMUST00000010254.9
syntaxin 5A
chr17_-_64331817 1.08 ENSMUST00000172733.1
ENSMUST00000172818.1
praja 2, RING-H2 motif containing
chr14_+_26638074 1.06 ENSMUST00000022429.2
ADP-ribosylation factor 4
chr5_+_110176868 1.05 ENSMUST00000139611.1
ENSMUST00000031477.8
golgi autoantigen, golgin subfamily a, 3
chr11_-_86807624 1.00 ENSMUST00000018569.7
DEAH (Asp-Glu-Ala-His) box polypeptide 40
chr6_-_54593139 1.00 ENSMUST00000046520.6
FK506 binding protein 14
chrX_+_56454871 1.00 ENSMUST00000039374.2
ENSMUST00000101553.2
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B
chr3_-_108086590 0.99 ENSMUST00000102638.1
ENSMUST00000102637.1
adenosine monophosphate deaminase 2
chr11_-_72795801 0.98 ENSMUST00000079681.5
cytochrome b5 domain containing 2
chr6_-_29212240 0.97 ENSMUST00000160878.1
ENSMUST00000078155.5
inosine 5'-phosphate dehydrogenase 1
chr14_+_26638237 0.96 ENSMUST00000112318.3
ADP-ribosylation factor 4
chrX_+_56346390 0.95 ENSMUST00000101560.3
zinc finger protein 449
chr11_-_96916407 0.94 ENSMUST00000130774.1
CDK5 regulatory subunit associated protein 3
chr2_+_155133501 0.94 ENSMUST00000029126.8
ENSMUST00000109685.1
itchy, E3 ubiquitin protein ligase
chr19_-_41263931 0.93 ENSMUST00000025989.8
transmembrane 9 superfamily member 3
chr2_-_155692317 0.92 ENSMUST00000103140.4
transient receptor potential cation channel, subfamily C, member 4 associated protein
chr9_+_57560934 0.92 ENSMUST00000045791.9
secretory carrier membrane protein 2
chr4_-_134000857 0.91 ENSMUST00000105887.1
ENSMUST00000012262.5
ENSMUST00000144668.1
ENSMUST00000105889.3
dehydrodolichyl diphosphate synthase
chr17_-_56183887 0.90 ENSMUST00000019723.7
DNA segment, Chr 17, Wayne State University 104, expressed
chr2_+_153875045 0.89 ENSMUST00000028983.2
BPI fold containing family B, member 2
chr3_+_89246397 0.89 ENSMUST00000168900.1
keratinocyte associated protein 2
chr13_-_100833369 0.89 ENSMUST00000067246.4
solute carrier family 30 (zinc transporter), member 5
chr10_+_85102627 0.88 ENSMUST00000095383.4
expressed sequence AI597468
chr9_+_104063376 0.87 ENSMUST00000120854.1
acyl-Coenzyme A dehydrogenase family, member 11
chr19_-_5771376 0.87 ENSMUST00000025890.8
SCY1-like 1 (S. cerevisiae)
chr11_-_96916366 0.83 ENSMUST00000144731.1
ENSMUST00000127048.1
CDK5 regulatory subunit associated protein 3
chr6_+_29348069 0.83 ENSMUST00000173216.1
ENSMUST00000031779.10
ENSMUST00000090481.7
calumenin
chr13_+_81657732 0.82 ENSMUST00000049055.6
LysM, putative peptidoglycan-binding, domain containing 3
chr3_-_84582616 0.82 ENSMUST00000143514.1
ADP-ribosylation factor interacting protein 1
chr4_+_137594140 0.80 ENSMUST00000105840.1
ENSMUST00000055131.6
ENSMUST00000105839.1
ENSMUST00000105838.1
ubiquitin specific peptidase 48
chr14_-_26638183 0.79 ENSMUST00000166902.1
RIKEN cDNA 4930570N19 gene
chr12_+_69184158 0.79 ENSMUST00000060579.8
mannoside acetylglucosaminyltransferase 2
chr7_+_28693032 0.78 ENSMUST00000151227.1
ENSMUST00000108281.1
F-box protein 27
chr7_-_122067263 0.77 ENSMUST00000033159.3
glutamyl-tRNA synthetase 2 (mitochondrial)(putative)
chr2_-_91070283 0.75 ENSMUST00000111436.2
ENSMUST00000073575.5
solute carrier family 39 (metal ion transporter), member 13
chr14_-_75754475 0.75 ENSMUST00000049168.7
component of oligomeric golgi complex 3
chr2_+_121140498 0.74 ENSMUST00000119031.1
ENSMUST00000110662.2
adenosine deaminase-like
chr10_-_24101951 0.72 ENSMUST00000170267.1
trace amine-associated receptor 8C
chr2_+_150786735 0.71 ENSMUST00000045441.7
brain glycogen phosphorylase
chr19_+_4214238 0.70 ENSMUST00000046506.6
cardiotrophin-like cytokine factor 1
chr11_-_20741580 0.70 ENSMUST00000035350.5
aftiphilin
chr17_-_47833256 0.68 ENSMUST00000152455.1
ENSMUST00000035375.7
MyoD family inhibitor
chr5_+_76974683 0.68 ENSMUST00000101087.3
ENSMUST00000120550.1
signal recognition particle 72
chr4_-_43000451 0.67 ENSMUST00000030164.7
valosin containing protein
chr2_+_121140407 0.67 ENSMUST00000028702.3
ENSMUST00000110665.1
adenosine deaminase-like
chr2_-_157204483 0.67 ENSMUST00000029170.7
retinoblastoma-like 1 (p107)
chr3_+_144570687 0.62 ENSMUST00000106211.1
selenoprotein
chr13_+_72628831 0.62 ENSMUST00000169028.1
Iroquois related homeobox 2 (Drosophila)
chr10_-_78753046 0.61 ENSMUST00000105383.2
coiled-coil domain containing 105
chr2_-_91070180 0.61 ENSMUST00000153367.1
ENSMUST00000079976.3
solute carrier family 39 (metal ion transporter), member 13
chr4_-_129640959 0.60 ENSMUST00000132217.1
ENSMUST00000130017.1
ENSMUST00000154105.1
taxilin alpha
chr11_-_68853119 0.60 ENSMUST00000018880.7
nuclear distribution gene E-like homolog 1 (A. nidulans)
chr4_-_129641060 0.60 ENSMUST00000046425.9
ENSMUST00000133803.1
taxilin alpha
chr7_+_49910112 0.60 ENSMUST00000056442.5
solute carrier family 6 (neurotransmitter transporter, glycine), member 5
chr6_-_82774448 0.60 ENSMUST00000000642.4
hexokinase 2
chr13_-_55321928 0.59 ENSMUST00000035242.7
RAB24, member RAS oncogene family
chr3_-_19628669 0.59 ENSMUST00000119133.1
RIKEN cDNA 1700064H15 gene
chr14_-_79301623 0.59 ENSMUST00000022595.7
regulator of cell cycle
chr7_+_122067164 0.58 ENSMUST00000033158.4
ubiquitin family domain containing 1
chr3_-_84582476 0.56 ENSMUST00000107687.2
ENSMUST00000098990.3
ADP-ribosylation factor interacting protein 1
chr7_+_100706623 0.54 ENSMUST00000107042.1
family with sequence similarity 168, member A
chr11_-_20741447 0.53 ENSMUST00000177543.1
aftiphilin
chr11_-_68853019 0.52 ENSMUST00000108672.1
nuclear distribution gene E-like homolog 1 (A. nidulans)
chr19_+_6276725 0.51 ENSMUST00000025684.3
EH-domain containing 1
chr6_-_52204415 0.50 ENSMUST00000048794.6
homeobox A5
chr6_-_101377342 0.45 ENSMUST00000151175.1
PDZ domain containing RING finger 3
chr1_+_119526125 0.45 ENSMUST00000183952.1
Transmembrane protein 185B
chr16_-_36874806 0.45 ENSMUST00000075946.5
ELL associated factor 2
chr5_-_72559599 0.44 ENSMUST00000074948.4
ENSMUST00000087216.5
nuclear transcription factor, X-box binding-like 1
chr6_-_113740675 0.42 ENSMUST00000032440.4
SEC13 homolog (S. cerevisiae)
chr11_-_59228162 0.42 ENSMUST00000163300.1
ENSMUST00000061242.7
ADP-ribosylation factor 1
chr5_-_100038869 0.42 ENSMUST00000153442.1
heterogeneous nuclear ribonucleoprotein D-like
chr3_-_9004686 0.42 ENSMUST00000120143.1
tumor protein D52
chr15_+_23036449 0.41 ENSMUST00000164787.1
cadherin 18
chr2_-_39065505 0.41 ENSMUST00000039165.8
golgi autoantigen, golgin subfamily a, 1
chr16_-_35490873 0.41 ENSMUST00000023550.7
protein disulfide isomerase associated 5
chrX_+_20658326 0.40 ENSMUST00000089217.4
ubiquitin-like modifier activating enzyme 1
chr14_-_60086832 0.40 ENSMUST00000080368.5
ATPase, aminophospholipid transporter-like, class I, type 8A, member 2
chr11_+_6561133 0.40 ENSMUST00000160633.1
cerebral cavernous malformation 2
chr7_+_100706702 0.39 ENSMUST00000049053.7
family with sequence similarity 168, member A
chr9_+_8900459 0.38 ENSMUST00000098986.3
ENSMUST00000070463.3
progesterone receptor
chr3_+_144570409 0.37 ENSMUST00000082437.3
selenoprotein
chr9_-_89705017 0.37 ENSMUST00000058488.6
transmembrane emp24 domain containing 3
chr16_-_32877723 0.34 ENSMUST00000119810.1
RIKEN cDNA 1700021K19 gene
chr12_+_69372112 0.32 ENSMUST00000050063.7
ADP-ribosylation factor 6
chr2_+_164497518 0.32 ENSMUST00000103101.4
ENSMUST00000117066.1
phosphatidylinositol glycan anchor biosynthesis, class T
chr19_+_8819401 0.32 ENSMUST00000096753.3
heterogeneous nuclear ribonucleoprotein U-like 2

Network of associatons between targets according to the STRING database.

First level regulatory network of Xbp1_Creb3l1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 6.5 GO:2000845 negative regulation of glucagon secretion(GO:0070093) positive regulation of testosterone secretion(GO:2000845)
1.0 13.8 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
1.0 3.9 GO:2000705 negative regulation of anion channel activity(GO:0010360) regulation of dense core granule biogenesis(GO:2000705)
0.9 2.6 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
0.8 4.2 GO:0006041 glucosamine metabolic process(GO:0006041)
0.8 10.1 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.7 7.4 GO:0048208 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.7 4.8 GO:0006621 protein retention in ER lumen(GO:0006621)
0.6 1.8 GO:2000793 cell proliferation involved in heart valve development(GO:2000793)
0.6 5.1 GO:0071569 protein ufmylation(GO:0071569)
0.5 1.6 GO:0019043 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990) establishment of viral latency(GO:0019043) release from viral latency(GO:0019046)
0.5 8.9 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.5 2.6 GO:1900619 acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.5 20.9 GO:0060445 branching involved in salivary gland morphogenesis(GO:0060445)
0.5 1.4 GO:0006154 adenosine catabolic process(GO:0006154)
0.4 1.3 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.4 2.1 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.4 2.0 GO:0002669 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.4 1.1 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.3 6.1 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.3 0.9 GO:1905053 regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053)
0.3 3.0 GO:1903298 regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903297) negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903298)
0.3 4.5 GO:0060510 Type II pneumocyte differentiation(GO:0060510)
0.3 12.1 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.3 4.1 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.3 1.6 GO:0070417 cellular response to cold(GO:0070417)
0.2 0.5 GO:0060435 bronchiole development(GO:0060435)
0.2 1.2 GO:0097167 circadian regulation of translation(GO:0097167)
0.2 0.7 GO:0043396 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397) positive regulation of isotype switching to IgE isotypes(GO:0048295) positive regulation of corticotropin-releasing hormone secretion(GO:0051466)
0.2 0.7 GO:0042726 flavin-containing compound metabolic process(GO:0042726)
0.2 1.3 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.2 0.4 GO:1902953 positive regulation of ER to Golgi vesicle-mediated transport(GO:1902953)
0.2 4.1 GO:0044126 regulation of growth of symbiont in host(GO:0044126)
0.2 0.6 GO:0003330 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.2 1.0 GO:0006177 GMP biosynthetic process(GO:0006177)
0.2 3.6 GO:0007289 spermatid nucleus differentiation(GO:0007289)
0.2 1.3 GO:2000138 positive regulation of cell proliferation involved in heart morphogenesis(GO:2000138)
0.2 0.5 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.2 2.2 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.2 0.6 GO:0072272 proximal/distal pattern formation involved in metanephric nephron development(GO:0072272)
0.2 6.6 GO:1903146 regulation of mitophagy(GO:1903146)
0.1 0.6 GO:0036233 glycine import(GO:0036233)
0.1 2.6 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.1 0.4 GO:0060748 paracrine signaling(GO:0038001) tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.1 1.0 GO:0032264 purine nucleotide salvage(GO:0032261) IMP salvage(GO:0032264)
0.1 1.1 GO:0051081 membrane disassembly(GO:0030397) nuclear envelope disassembly(GO:0051081)
0.1 0.8 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.1 2.6 GO:0045793 positive regulation of cell size(GO:0045793)
0.1 1.0 GO:0016093 polyprenol metabolic process(GO:0016093)
0.1 0.9 GO:0061088 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.1 4.1 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.1 1.4 GO:0006851 mitochondrial calcium ion transport(GO:0006851)
0.1 4.5 GO:0045454 cell redox homeostasis(GO:0045454)
0.1 1.4 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.1 1.2 GO:0006491 N-glycan processing(GO:0006491)
0.1 0.4 GO:0061091 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.1 0.3 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 1.9 GO:0006356 regulation of transcription from RNA polymerase I promoter(GO:0006356)
0.0 3.7 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.0 0.4 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0 0.9 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.9 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.0 0.4 GO:0060837 blood vessel endothelial cell differentiation(GO:0060837)
0.0 2.2 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.2 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 1.1 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 1.8 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 2.7 GO:0007030 Golgi organization(GO:0007030)
0.0 0.2 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.1 GO:2000680 regulation of rubidium ion transport(GO:2000680)
0.0 0.3 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 2.7 GO:0008203 cholesterol metabolic process(GO:0008203)
0.0 0.6 GO:0048820 hair follicle maturation(GO:0048820)
0.0 0.3 GO:0097284 hepatocyte apoptotic process(GO:0097284)
0.0 2.7 GO:1903169 regulation of calcium ion transmembrane transport(GO:1903169)
0.0 8.3 GO:0007283 spermatogenesis(GO:0007283)
0.0 0.1 GO:0061727 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0 0.2 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.0 0.1 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 0.2 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 0.5 GO:0043550 regulation of lipid kinase activity(GO:0043550)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 5.5 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.7 14.7 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.7 2.1 GO:0070939 Dsl1p complex(GO:0070939)
0.6 8.2 GO:0030126 COPI vesicle coat(GO:0030126)
0.5 4.1 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.5 2.3 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.4 9.2 GO:0005797 Golgi medial cisterna(GO:0005797)
0.4 4.5 GO:0030137 COPI-coated vesicle(GO:0030137)
0.3 1.2 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.2 3.7 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.2 0.7 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.2 3.7 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.2 2.4 GO:0017119 Golgi transport complex(GO:0017119)
0.2 2.5 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.2 0.7 GO:0097059 CRLF-CLCF1 complex(GO:0097058) CNTFR-CLCF1 complex(GO:0097059)
0.2 2.6 GO:0043083 synaptic cleft(GO:0043083)
0.2 0.5 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.1 0.4 GO:0032783 ELL-EAF complex(GO:0032783)
0.1 1.1 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.1 4.7 GO:0005801 cis-Golgi network(GO:0005801)
0.1 1.6 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.1 2.7 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 3.7 GO:0031201 SNARE complex(GO:0031201)
0.1 2.3 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 0.9 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.1 3.9 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 0.3 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.1 0.1 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.0 1.4 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.4 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 3.5 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 1.4 GO:0032590 dendrite membrane(GO:0032590)
0.0 0.1 GO:0072487 MSL complex(GO:0072487)
0.0 50.2 GO:0005783 endoplasmic reticulum(GO:0005783)
0.0 0.3 GO:0090543 Flemming body(GO:0090543)
0.0 1.0 GO:0005795 Golgi stack(GO:0005795)
0.0 2.0 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.1 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.3 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.6 GO:0005776 autophagosome(GO:0005776)
0.0 12.9 GO:0016604 nuclear body(GO:0016604)
0.0 15.9 GO:0005794 Golgi apparatus(GO:0005794)
0.0 0.8 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 2.6 GO:0016323 basolateral plasma membrane(GO:0016323)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.9 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
1.2 3.7 GO:0042954 lipoprotein transporter activity(GO:0042954)
1.2 4.8 GO:0046923 ER retention sequence binding(GO:0046923)
0.7 2.6 GO:0004104 cholinesterase activity(GO:0004104)
0.5 1.6 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.4 1.6 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.3 9.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.3 0.9 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.3 3.7 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.3 2.4 GO:0001594 trace-amine receptor activity(GO:0001594)
0.3 1.3 GO:0004985 opioid receptor activity(GO:0004985)
0.2 1.0 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.2 1.1 GO:0070012 oligopeptidase activity(GO:0070012)
0.2 5.0 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.2 2.6 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.2 1.3 GO:0005047 signal recognition particle binding(GO:0005047)
0.2 7.9 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.2 0.7 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.2 0.7 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.2 4.2 GO:0008483 transaminase activity(GO:0008483)
0.2 5.5 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.1 2.7 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.1 1.2 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.1 19.7 GO:0000149 SNARE binding(GO:0000149)
0.1 1.0 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 3.8 GO:0070566 adenylyltransferase activity(GO:0070566)
0.1 2.2 GO:0042288 MHC class I protein binding(GO:0042288)
0.1 1.3 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.1 1.4 GO:0004000 adenosine deaminase activity(GO:0004000)
0.1 2.6 GO:0019789 SUMO transferase activity(GO:0019789)
0.1 0.7 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.1 0.6 GO:0008865 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 0.2 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.1 0.9 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 6.0 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 2.9 GO:0005246 calcium channel regulator activity(GO:0005246)
0.1 0.4 GO:0034046 poly(G) binding(GO:0034046)
0.1 7.7 GO:0008565 protein transporter activity(GO:0008565)
0.1 18.5 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.1 0.3 GO:0031996 thioesterase binding(GO:0031996)
0.1 1.7 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 1.1 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.1 0.9 GO:0004659 prenyltransferase activity(GO:0004659)
0.1 0.3 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.1 3.0 GO:0070888 E-box binding(GO:0070888)
0.0 0.6 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.4 GO:0016004 phospholipase activator activity(GO:0016004) lipase activator activity(GO:0060229)
0.0 0.3 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 1.7 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.2 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 1.2 GO:0030276 clathrin binding(GO:0030276)
0.0 0.1 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.0 1.3 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 2.1 GO:0020037 heme binding(GO:0020037)
0.0 0.1 GO:0046972 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 0.7 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 1.1 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.1 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0 0.8 GO:0000049 tRNA binding(GO:0000049)
0.0 9.1 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.6 GO:0070412 R-SMAD binding(GO:0070412)
0.0 1.0 GO:0003724 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.3 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.1 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0 0.8 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.0 0.0 GO:0072541 peroxynitrite reductase activity(GO:0072541)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.9 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.2 2.6 ST JAK STAT PATHWAY Jak-STAT Pathway
0.2 5.4 PID ARF 3PATHWAY Arf1 pathway
0.1 1.8 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 1.6 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 1.2 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.1 1.3 PID IL5 PATHWAY IL5-mediated signaling events
0.0 1.8 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 2.5 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 2.0 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 3.6 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 6.8 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.8 PID AURORA A PATHWAY Aurora A signaling
0.0 1.4 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 2.0 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.0 0.3 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.4 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.9 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.7 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 7.4 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.4 7.9 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.4 8.2 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.4 3.9 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.3 14.1 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.2 4.1 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.2 1.6 REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.1 2.4 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 1.4 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 14.0 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.1 4.1 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 2.6 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.1 1.0 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 1.6 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 1.6 REACTOME PERK REGULATED GENE EXPRESSION Genes involved in PERK regulated gene expression
0.0 0.8 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 1.7 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.6 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.8 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 1.1 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.7 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 1.2 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 4.1 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.3 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 1.2 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.4 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 1.1 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.2 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.7 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis