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12D miR HR13_24

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Results for Nr4a2

Z-value: 0.85

Motif logo

Transcription factors associated with Nr4a2

Gene Symbol Gene ID Gene Info
ENSMUSG00000026826.7 nuclear receptor subfamily 4, group A, member 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nr4a2mm10_v2_chr2_-_57113053_57113072-0.749.7e-03Click!

Activity profile of Nr4a2 motif

Sorted Z-values of Nr4a2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_129699833 3.56 ENSMUST00000028883.5
prodynorphin
chr11_-_109722214 2.04 ENSMUST00000020938.7
family with sequence similarity 20, member A
chr17_+_69439326 1.87 ENSMUST00000169935.1
RIKEN cDNA A330050F15 gene
chr17_+_70522083 1.54 ENSMUST00000148486.1
ENSMUST00000133717.1
discs, large (Drosophila) homolog-associated protein 1
chr13_-_92131494 1.22 ENSMUST00000099326.3
ENSMUST00000146492.1
RAS protein-specific guanine nucleotide-releasing factor 2
chr8_+_68880491 1.10 ENSMUST00000015712.8
lipoprotein lipase
chr6_+_96113146 1.05 ENSMUST00000122120.1
family with sequence similarity 19, member A1
chr1_-_124045247 1.05 ENSMUST00000112603.2
dipeptidylpeptidase 10
chr8_-_64733534 0.99 ENSMUST00000141021.1
sterol-C4-methyl oxidase-like
chr15_-_68363139 0.98 ENSMUST00000175699.1
predicted gene 20732
chr5_+_102845007 0.97 ENSMUST00000070000.4
Rho GTPase activating protein 24
chr9_+_108392820 0.87 ENSMUST00000035234.4
RIKEN cDNA 1700102P08 gene
chr17_+_29360923 0.77 ENSMUST00000024810.6
FYVE, RhoGEF and PH domain containing 2
chr4_+_150914562 0.67 ENSMUST00000135169.1
tumor necrosis factor receptor superfamily, member 9
chr7_+_102267795 0.62 ENSMUST00000033289.4
stromal interaction molecule 1
chr13_+_74121435 0.61 ENSMUST00000036208.6
solute carrier family 9 (sodium/hydrogen exchanger), member 3
chr9_-_22002599 0.55 ENSMUST00000115336.2
ENSMUST00000044926.5
coiled-coil domain containing 151
chr2_+_61593125 0.54 ENSMUST00000112494.1
TRAF family member-associated Nf-kappa B activator
chr4_+_33081505 0.51 ENSMUST00000147889.1
gamma-aminobutyric acid (GABA) C receptor, subunit rho 2
chr10_-_42478280 0.51 ENSMUST00000151747.1
lactation elevated 1
chr6_-_138422898 0.51 ENSMUST00000161450.1
ENSMUST00000163024.1
ENSMUST00000162185.1
LIM domain only 3
chr3_+_89436699 0.50 ENSMUST00000038942.3
ENSMUST00000130858.1
pre B cell leukemia transcription factor interacting protein 1
chr3_-_88027465 0.48 ENSMUST00000005014.2
hyaluronan and proteoglycan link protein 2
chr15_+_25773985 0.48 ENSMUST00000125667.1
myosin X
chr2_+_30595037 0.48 ENSMUST00000102853.3
CSA-conditional, T cell activation-dependent protein
chr9_+_98864767 0.47 ENSMUST00000167951.1
RIKEN cDNA 2410012M07 gene
chr5_-_67099235 0.46 ENSMUST00000012664.8
paired-like homeobox 2b
chr19_-_32061438 0.46 ENSMUST00000096119.4
N-acylsphingosine amidohydrolase 2
chr2_+_61593077 0.46 ENSMUST00000112495.1
ENSMUST00000112501.2
TRAF family member-associated Nf-kappa B activator
chr10_-_20725023 0.45 ENSMUST00000020165.7
phosphodiesterase 7B
chr4_-_42528175 0.44 ENSMUST00000180201.1
predicted gene 13298
chr9_+_118506226 0.44 ENSMUST00000084820.4
golgi autoantigen, golgin subfamily a, 4
chr3_-_108086590 0.44 ENSMUST00000102638.1
ENSMUST00000102637.1
adenosine monophosphate deaminase 2
chr7_+_105554360 0.43 ENSMUST00000046983.8
sphingomyelin phosphodiesterase 1, acid lysosomal
chr7_+_4119525 0.43 ENSMUST00000119661.1
ENSMUST00000129423.1
tweety homolog 1 (Drosophila)
chr7_+_4119556 0.42 ENSMUST00000079415.5
tweety homolog 1 (Drosophila)
chr18_+_86711059 0.40 ENSMUST00000068423.3
cerebellin 2 precursor protein
chr19_+_46152505 0.39 ENSMUST00000026254.7
golgi-specific brefeldin A-resistance factor 1
chr10_-_20724696 0.39 ENSMUST00000170265.1
phosphodiesterase 7B
chr5_-_66151903 0.38 ENSMUST00000167950.1
RNA binding motif protein 47
chr3_+_89436736 0.35 ENSMUST00000146630.1
ENSMUST00000145753.1
pre B cell leukemia transcription factor interacting protein 1
chr11_+_70657687 0.35 ENSMUST00000134087.1
ENSMUST00000170716.1
enolase 3, beta muscle
chr9_+_22003035 0.35 ENSMUST00000115331.2
ENSMUST00000003493.7
protein kinase C substrate 80K-H
chr11_+_70657196 0.34 ENSMUST00000157027.1
ENSMUST00000072841.5
ENSMUST00000108548.1
ENSMUST00000126241.1
enolase 3, beta muscle
chr5_+_63649335 0.33 ENSMUST00000159584.1
RIKEN cDNA 3110047P20 gene
chr16_+_8830093 0.33 ENSMUST00000023150.5
RIKEN cDNA 1810013L24 gene
chr5_+_111581422 0.32 ENSMUST00000064930.3
RIKEN cDNA C130026L21 gene
chr2_-_13491900 0.31 ENSMUST00000091436.5
cubilin (intrinsic factor-cobalamin receptor)
chr3_+_122895072 0.31 ENSMUST00000023820.5
fatty acid binding protein 2, intestinal
chr15_+_54952939 0.30 ENSMUST00000181704.1
predicted gene, 26684
chr11_-_79504078 0.30 ENSMUST00000164465.2
oligodendrocyte myelin glycoprotein
chr1_-_167393826 0.29 ENSMUST00000028005.2
microsomal glutathione S-transferase 3
chr3_-_95133989 0.29 ENSMUST00000172572.2
ENSMUST00000173462.2
sodium channel modifier 1
chr19_-_45998479 0.28 ENSMUST00000045396.7
RIKEN cDNA 9130011E15 gene
chr8_+_104847061 0.28 ENSMUST00000055052.5
carboxylesterase 2C
chr17_+_47737030 0.28 ENSMUST00000086932.3
transcription factor EB
chr4_-_42853888 0.27 ENSMUST00000107979.1
predicted gene 12429
chr7_-_100514800 0.27 ENSMUST00000054923.7
DnaJ (Hsp40) related, subfamily B, member 13
chrX_+_160768013 0.27 ENSMUST00000033650.7
retinoschisis (X-linked, juvenile) 1 (human)
chr3_+_95134088 0.27 ENSMUST00000066386.5
LysM, putative peptidoglycan-binding, domain containing 1
chr5_-_67099045 0.27 ENSMUST00000174251.1
paired-like homeobox 2b
chr19_+_43782181 0.26 ENSMUST00000026208.4
ATP-binding cassette, sub-family C (CFTR/MRP), member 2
chr19_+_45998131 0.26 ENSMUST00000181820.1
RIKEN cDNA 4930505N22 gene
chr3_-_144932523 0.26 ENSMUST00000098549.3
expressed sequence AI747448
chr16_-_20426375 0.26 ENSMUST00000079158.6
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr7_-_19950729 0.26 ENSMUST00000043440.6
immunoglobulin superfamily, member 23
chr9_-_32344237 0.26 ENSMUST00000034533.5
potassium inwardly-rectifying channel, subfamily J, member 5
chr16_-_20426322 0.26 ENSMUST00000115547.2
ENSMUST00000096199.4
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr18_+_57142782 0.25 ENSMUST00000139892.1
multiple EGF-like-domains 10
chr6_+_92091378 0.25 ENSMUST00000113460.1
nuclear receptor subfamily 2, group C, member 2
chr4_+_99955715 0.24 ENSMUST00000102783.4
phosphoglucomutase 2
chr10_-_42478488 0.24 ENSMUST00000041024.8
lactation elevated 1
chr5_-_66151323 0.24 ENSMUST00000131838.1
RNA binding motif protein 47
chr1_+_182409162 0.23 ENSMUST00000117245.1
transformation related protein 53 binding protein 2
chr1_-_24100306 0.23 ENSMUST00000027337.8
family with sequence similarity 135, member A
chr2_-_73892588 0.21 ENSMUST00000154456.1
ENSMUST00000090802.4
ENSMUST00000055833.5
activating transcription factor 2
chr9_-_64737623 0.20 ENSMUST00000169058.1
RAB11a, member RAS oncogene family
chr2_-_73892619 0.20 ENSMUST00000112007.1
ENSMUST00000112016.2
activating transcription factor 2
chrX_-_142390334 0.20 ENSMUST00000112907.1
acyl-CoA synthetase long-chain family member 4
chr4_+_102760135 0.20 ENSMUST00000066824.7
SH3-domain GRB2-like (endophilin) interacting protein 1
chr9_-_64737684 0.20 ENSMUST00000171100.1
ENSMUST00000167569.1
ENSMUST00000004892.6
ENSMUST00000172298.1
RAB11a, member RAS oncogene family
chr18_-_56975333 0.20 ENSMUST00000139243.2
ENSMUST00000025488.8
RIKEN cDNA C330018D20 gene
chr4_-_83021102 0.19 ENSMUST00000071708.5
Fras1 related extracellular matrix protein 1
chr5_-_121527186 0.18 ENSMUST00000152270.1
MAP kinase-activated protein kinase 5
chr11_-_100822525 0.17 ENSMUST00000107358.2
signal transducer and activator of transcription 5B
chr11_-_61494173 0.17 ENSMUST00000101085.2
ENSMUST00000079080.6
ENSMUST00000108714.1
mitogen-activated protein kinase 7
chr4_-_36136463 0.17 ENSMUST00000098151.2
leucine rich repeat and Ig domain containing 2
chr1_-_87573825 0.17 ENSMUST00000068681.5
neuronal guanine nucleotide exchange factor
chr2_+_127338639 0.17 ENSMUST00000059839.2
astacin-like metalloendopeptidase (M12 family)
chrX_+_150589907 0.16 ENSMUST00000080884.4
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr2_-_163417092 0.16 ENSMUST00000127038.1
oxidative stress responsive serine rich 1
chr14_-_30915387 0.16 ENSMUST00000166622.1
inter-alpha trypsin inhibitor, heavy chain 3
chr1_+_57845534 0.15 ENSMUST00000169772.1
spermatogenesis associated, serine-rich 2-like
chr17_-_35910032 0.14 ENSMUST00000141662.1
ENSMUST00000056034.6
ENSMUST00000077494.6
ENSMUST00000149277.1
ENSMUST00000061052.5
alpha tubulin acetyltransferase 1
chr7_+_125603420 0.14 ENSMUST00000033000.6
interleukin 21 receptor
chr8_-_84044982 0.14 ENSMUST00000061923.4
relaxin 3
chr16_-_44139630 0.14 ENSMUST00000137557.1
ENSMUST00000147025.1
ATPase, H+ transporting, lysosomal V1 subunit A
chr2_-_155945282 0.14 ENSMUST00000040162.2
growth differentiation factor 5
chr10_+_53337686 0.13 ENSMUST00000046221.6
ENSMUST00000163319.1
phospholamban
chr1_+_137966529 0.13 ENSMUST00000182158.1
RIKEN cDNA A430106G13 gene
chr4_+_102760294 0.13 ENSMUST00000072481.5
ENSMUST00000156596.1
ENSMUST00000080728.6
ENSMUST00000106882.2
SH3-domain GRB2-like (endophilin) interacting protein 1
chr13_+_94875600 0.13 ENSMUST00000022195.10
orthopedia homolog (Drosophila)
chr4_+_136357423 0.12 ENSMUST00000182167.1
predicted gene, 17388
chr17_-_17624458 0.12 ENSMUST00000041047.2
leucyl/cystinyl aminopeptidase
chr4_-_141623799 0.12 ENSMUST00000038661.7
solute carrier family 25, member 34
chr12_+_31438209 0.12 ENSMUST00000001254.5
solute carrier family 26, member 3
chr15_-_42676967 0.12 ENSMUST00000022921.5
angiopoietin 1
chr2_-_73892530 0.12 ENSMUST00000136958.1
ENSMUST00000112010.2
ENSMUST00000128531.1
ENSMUST00000112017.1
activating transcription factor 2
chr2_+_144033059 0.12 ENSMUST00000037722.2
ENSMUST00000110032.1
barrier to autointegration factor 2
chr11_+_121702591 0.12 ENSMUST00000125580.1
meteorin, glial cell differentiation regulator-like
chr13_-_17805093 0.11 ENSMUST00000042365.7
cyclin-dependent kinase 13
chr6_-_125236974 0.11 ENSMUST00000112281.1
CD27 antigen
chr3_-_20275659 0.11 ENSMUST00000011607.5
carboxypeptidase B1 (tissue)
chr16_-_44139196 0.11 ENSMUST00000063661.6
ENSMUST00000114666.2
ATPase, H+ transporting, lysosomal V1 subunit A
chr2_+_132781278 0.10 ENSMUST00000028826.3
chromogranin B
chr19_-_8405060 0.10 ENSMUST00000064507.5
ENSMUST00000120540.1
ENSMUST00000096269.4
solute carrier family 22, member 30
chr19_+_3767953 0.10 ENSMUST00000113970.1
suppressor of variegation 4-20 homolog 1 (Drosophila)
chr10_+_90829835 0.10 ENSMUST00000179964.1
ankyrin repeat and sterile alpha motif domain containing 1B
chr13_+_118714678 0.09 ENSMUST00000022246.8
fibroblast growth factor 10
chr12_-_76795489 0.09 ENSMUST00000082431.3
glutathione peroxidase 2
chr10_+_42502197 0.09 ENSMUST00000105499.1
sorting nexin 3
chr11_-_109472611 0.09 ENSMUST00000168740.1
solute carrier family 16 (monocarboxylic acid transporters), member 6
chr15_-_89425795 0.08 ENSMUST00000168376.1
carnitine palmitoyltransferase 1b, muscle
chr8_-_119840522 0.08 ENSMUST00000168698.1
ENSMUST00000034285.6
coactosin-like 1 (Dictyostelium)
chr2_-_101621033 0.08 ENSMUST00000090513.4
RIKEN cDNA B230118H07 gene
chr2_-_59160644 0.07 ENSMUST00000077687.5
coiled-coil domain containing 148
chr6_-_125236996 0.06 ENSMUST00000032486.6
CD27 antigen
chr10_+_90829780 0.06 ENSMUST00000179337.2
ankyrin repeat and sterile alpha motif domain containing 1B
chr18_+_36664060 0.05 ENSMUST00000036765.7
eukaryotic translation initiation factor 4E binding protein 3
chr6_-_125236953 0.05 ENSMUST00000112282.2
CD27 antigen
chr2_+_105668888 0.05 ENSMUST00000111086.4
ENSMUST00000111087.3
paired box gene 6
chr5_-_31202215 0.05 ENSMUST00000176245.1
ENSMUST00000177310.1
ENSMUST00000114590.1
zinc finger protein 513
chr6_+_113697050 0.04 ENSMUST00000089018.4
TatD DNase domain containing 2
chr6_+_48613180 0.03 ENSMUST00000061720.4
zinc finger protein 775
chr18_-_15063560 0.03 ENSMUST00000168989.1
potassium channel tetramerisation domain containing 1
chr5_+_135187251 0.03 ENSMUST00000002825.5
bromodomain adjacent to zinc finger domain, 1B
chr17_-_43667015 0.03 ENSMUST00000024705.4
solute carrier family 25, member 27
chr2_+_173153048 0.02 ENSMUST00000029017.5
phosphoenolpyruvate carboxykinase 1, cytosolic
chr8_-_13494479 0.01 ENSMUST00000033828.5
growth arrest specific 6
chr2_-_120563795 0.01 ENSMUST00000055241.6
ENSMUST00000135625.1
zinc finger protein 106
chr7_-_133602110 0.01 ENSMUST00000033275.2
testis expressed 36
chr13_-_97747373 0.01 ENSMUST00000123535.1
RIKEN cDNA 5330416C01 gene
chr10_-_40302186 0.01 ENSMUST00000099945.4
S-adenosylmethionine decarboxylase 1
chr3_-_144975011 0.01 ENSMUST00000075496.4
ENSMUST00000029923.6
chloride channel calcium activated 6
chr19_+_3768112 0.01 ENSMUST00000005518.9
ENSMUST00000113967.1
ENSMUST00000152935.1
ENSMUST00000176262.1
ENSMUST00000176407.1
ENSMUST00000176926.1
ENSMUST00000176512.1
suppressor of variegation 4-20 homolog 1 (Drosophila)

Network of associatons between targets according to the STRING database.

First level regulatory network of Nr4a2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.2 0.7 GO:0048880 hindbrain tangential cell migration(GO:0021934) sensory system development(GO:0048880)
0.2 2.7 GO:0070166 enamel mineralization(GO:0070166)
0.2 1.1 GO:0055096 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096)
0.2 0.7 GO:2001183 negative regulation of interleukin-12 secretion(GO:2001183)
0.1 0.4 GO:0035964 COPI-coated vesicle budding(GO:0035964) protein localization to endoplasmic reticulum exit site(GO:0070973)
0.1 1.5 GO:0070842 aggresome assembly(GO:0070842)
0.1 1.0 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.1 0.5 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
0.1 0.3 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.1 0.3 GO:0036367 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.1 0.4 GO:0010796 regulation of multivesicular body size(GO:0010796)
0.1 0.5 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.1 0.3 GO:0009816 defense response to bacterium, incompatible interaction(GO:0009816) regulation of defense response to bacterium, incompatible interaction(GO:1902477)
0.1 0.6 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 0.2 GO:0070375 ERK5 cascade(GO:0070375)
0.1 0.4 GO:0032264 IMP salvage(GO:0032264)
0.1 0.4 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 0.3 GO:0015889 cobalamin transport(GO:0015889)
0.1 0.3 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.1 0.2 GO:0032304 negative regulation of icosanoid secretion(GO:0032304)
0.1 3.5 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.2 GO:0050787 detoxification of mercury ion(GO:0050787)
0.0 0.1 GO:0070676 intralumenal vesicle formation(GO:0070676)
0.0 0.2 GO:2000360 negative regulation of binding of sperm to zona pellucida(GO:2000360)
0.0 0.6 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.1 GO:0030210 heparin biosynthetic process(GO:0030210)
0.0 0.3 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.2 GO:0043654 skeletal muscle satellite cell activation(GO:0014719) recognition of apoptotic cell(GO:0043654)
0.0 0.6 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.1 GO:0060435 bronchiole development(GO:0060435) secretion by lung epithelial cell involved in lung growth(GO:0061033) white fat cell proliferation(GO:0070343) regulation of white fat cell proliferation(GO:0070350) positive regulation of hair follicle cell proliferation(GO:0071338)
0.0 0.2 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.2 GO:0070672 development of secondary male sexual characteristics(GO:0046544) response to interleukin-15(GO:0070672)
0.0 0.9 GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.0 0.2 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.0 0.1 GO:0060591 chondroblast differentiation(GO:0060591)
0.0 0.2 GO:0090400 stress-induced premature senescence(GO:0090400)
0.0 0.5 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.2 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.1 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.0 0.3 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.2 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 1.0 GO:1903078 positive regulation of protein localization to plasma membrane(GO:1903078)
0.0 0.8 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.1 GO:0086023 adrenergic receptor signaling pathway involved in heart process(GO:0086023)
0.0 0.2 GO:0048520 positive regulation of behavior(GO:0048520)
0.0 0.2 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0 0.2 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 0.1 GO:0015747 urate transport(GO:0015747)
0.0 0.0 GO:0071929 alpha-tubulin acetylation(GO:0071929)
0.0 0.1 GO:0008272 sulfate transport(GO:0008272)
0.0 0.3 GO:0032291 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.0 0.2 GO:0036295 cellular response to increased oxygen levels(GO:0036295)
0.0 0.1 GO:0021979 hypothalamus cell differentiation(GO:0021979)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.1 0.7 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 0.3 GO:0043202 lysosomal lumen(GO:0043202)
0.1 0.6 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.1 1.1 GO:0042627 chylomicron(GO:0042627)
0.1 0.4 GO:0005828 kinetochore microtubule(GO:0005828)
0.1 0.2 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.0 0.4 GO:0042599 lamellar body(GO:0042599)
0.0 0.5 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.2 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.0 0.2 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.3 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 0.3 GO:0045179 apical cortex(GO:0045179)
0.0 0.3 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 3.6 GO:0043679 axon terminus(GO:0043679)
0.0 0.2 GO:0032156 septin cytoskeleton(GO:0032156)
0.0 0.5 GO:0035861 site of double-strand break(GO:0035861)
0.0 1.0 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.1 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.6 GO:0001515 opioid peptide activity(GO:0001515)
0.2 1.0 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.2 0.8 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.1 1.0 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.1 0.3 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.1 0.7 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 0.5 GO:0017040 ceramidase activity(GO:0017040)
0.1 0.3 GO:0030492 hemoglobin binding(GO:0030492)
0.1 2.0 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.1 0.4 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.5 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.4 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.6 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.6 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.3 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.2 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.2 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.3 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.9 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.8 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.2 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 0.5 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.2 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 2.2 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.2 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.4 GO:0031489 myosin V binding(GO:0031489)
0.0 0.4 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.1 GO:0036122 BMP binding(GO:0036122)
0.0 0.1 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.0 0.1 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 0.4 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.1 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.2 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 1.1 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.4 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.4 PID ARF 3PATHWAY Arf1 pathway
0.0 0.4 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.0 0.5 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.4 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.7 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.6 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 2.4 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.2 PID IL5 PATHWAY IL5-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.6 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.1 0.6 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 1.0 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 1.2 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.1 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.4 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.3 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.5 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.5 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.4 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.5 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 0.4 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0 0.2 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.2 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.3 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.9 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.3 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.4 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.4 REACTOME GLYCOLYSIS Genes involved in Glycolysis