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12D miR HR13_24

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Results for Nfic_Nfib

Z-value: 1.75

Motif logo

Transcription factors associated with Nfic_Nfib

Gene Symbol Gene ID Gene Info
ENSMUSG00000055053.11 nuclear factor I/C
ENSMUSG00000008575.11 nuclear factor I/B

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nficmm10_v2_chr10_-_81407641_81407683-0.841.1e-03Click!
Nfibmm10_v2_chr4_-_82505707_82505739-0.757.8e-03Click!

Activity profile of Nfic_Nfib motif

Sorted Z-values of Nfic_Nfib motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_127890918 7.12 ENSMUST00000121394.1
protease, serine, 53
chr5_-_139813237 4.55 ENSMUST00000110832.1
transmembrane protein 184a
chr19_-_42752710 3.77 ENSMUST00000076505.3
pyridine nucleotide-disulphide oxidoreductase domain 2
chr2_-_103283760 3.67 ENSMUST00000111174.1
ets homologous factor
chr11_-_109722214 3.41 ENSMUST00000020938.7
family with sequence similarity 20, member A
chr4_+_120161206 3.33 ENSMUST00000030384.4
endothelin 2
chr11_+_3989924 3.15 ENSMUST00000109981.1
galactose-3-O-sulfotransferase 1
chr16_+_30008657 3.13 ENSMUST00000181485.1
RIKEN cDNA 4632428C04 gene
chr11_+_115154139 3.09 ENSMUST00000021076.5
RAB37, member of RAS oncogene family
chr17_+_69439326 2.87 ENSMUST00000169935.1
RIKEN cDNA A330050F15 gene
chr19_+_32619997 2.64 ENSMUST00000025833.6
3'-phosphoadenosine 5'-phosphosulfate synthase 2
chr17_+_34969912 2.63 ENSMUST00000173680.1
predicted gene 20481
chr4_+_40920047 2.58 ENSMUST00000030122.4
serine peptidase inhibitor, Kazal type 4
chr4_+_143349757 2.50 ENSMUST00000052458.2
leucine rich repeat containing 38
chr1_+_40266578 2.46 ENSMUST00000114795.1
interleukin 1 receptor, type I
chr2_+_181219998 2.43 ENSMUST00000050026.6
ENSMUST00000108835.1
cDNA sequence BC051628
chr4_-_93335510 2.35 ENSMUST00000066774.4
tumor suppressor candidate 1
chr2_+_129592914 2.35 ENSMUST00000103203.1
signal-regulatory protein alpha
chr5_+_102768771 2.32 ENSMUST00000112852.1
Rho GTPase activating protein 24
chr2_+_129592818 2.27 ENSMUST00000153491.1
ENSMUST00000161620.1
ENSMUST00000179001.1
signal-regulatory protein alpha
chr18_-_32139570 2.22 ENSMUST00000171765.1
protein C
chr14_+_59625281 2.01 ENSMUST00000053949.5
shisa homolog 2 (Xenopus laevis)
chr4_+_41762309 1.94 ENSMUST00000108042.2
interleukin 11 receptor, alpha chain 1
chr4_-_57916283 1.93 ENSMUST00000063816.5
RIKEN cDNA D630039A03 gene
chr10_-_81291227 1.81 ENSMUST00000045744.6
tight junction protein 3
chr10_-_105574435 1.77 ENSMUST00000061506.8
transmembrane and tetratricopeptide repeat containing 2
chr18_+_33464163 1.72 ENSMUST00000097634.3
predicted gene 10549
chr8_+_106510853 1.67 ENSMUST00000080797.6
cadherin 3
chr3_+_94933041 1.65 ENSMUST00000090839.5
selenium binding protein 1
chr7_-_19796789 1.62 ENSMUST00000108449.2
ENSMUST00000043822.7
Casitas B-lineage lymphoma c
chr3_+_57736056 1.58 ENSMUST00000041826.9
ring finger protein 13
chr16_+_23429133 1.54 ENSMUST00000038730.6
receptor transporter protein 1
chr15_-_101370125 1.54 ENSMUST00000077196.4
keratin 80
chr11_+_78324200 1.52 ENSMUST00000102478.3
aldolase C, fructose-bisphosphate
chr12_-_78983476 1.47 ENSMUST00000070174.7
transmembrane protein 229B
chr5_+_24413406 1.45 ENSMUST00000049346.5
acid-sensing (proton-gated) ion channel 3
chr14_-_118052235 1.43 ENSMUST00000022725.2
dopachrome tautomerase
chr16_+_90831113 1.40 ENSMUST00000037539.7
ENSMUST00000099543.3
eva-1 homolog C (C. elegans)
chr3_-_85746266 1.40 ENSMUST00000118408.1
family with sequence similarity 160, member A1
chr14_+_103513328 1.38 ENSMUST00000095576.3
sciellin
chr5_+_149006948 1.34 ENSMUST00000124198.1
predicted gene 15408
chr12_-_26456423 1.33 ENSMUST00000020970.7
radical S-adenosyl methionine domain containing 2
chr15_+_102102926 1.32 ENSMUST00000169627.1
ENSMUST00000046144.9
tensin like C1 domain-containing phosphatase
chr6_+_17306415 1.31 ENSMUST00000150901.1
caveolin 1, caveolae protein
chr1_-_126830632 1.31 ENSMUST00000112583.1
ENSMUST00000094609.3
NCK-associated protein 5
chr1_+_40225051 1.30 ENSMUST00000027241.4
interleukin 1 receptor, type I
chr11_+_96931387 1.29 ENSMUST00000107633.1
proline rich 15-like
chr5_-_24329556 1.27 ENSMUST00000115098.2
potassium voltage-gated channel, subfamily H (eag-related), member 2
chr1_+_174501796 1.26 ENSMUST00000030039.7
formin 2
chr6_-_145250177 1.24 ENSMUST00000111710.1
ENSMUST00000155145.1
ENSMUST00000032399.5
v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
chr5_-_139819906 1.18 ENSMUST00000147328.1
transmembrane protein 184a
chr3_-_129755305 1.16 ENSMUST00000029653.2
epidermal growth factor
chr6_-_55175019 1.15 ENSMUST00000003569.5
indolethylamine N-methyltransferase
chr9_-_121792478 1.15 ENSMUST00000035110.4
hedgehog acyltransferase-like
chr10_+_62133082 1.13 ENSMUST00000050103.1
neurogenin 3
chr12_-_80132802 1.13 ENSMUST00000180643.1
RIKEN cDNA 2310015A10 gene
chr11_-_69858723 1.11 ENSMUST00000001626.3
ENSMUST00000108626.1
tyrosine kinase, non-receptor, 1
chr3_+_94693556 1.11 ENSMUST00000090848.3
ENSMUST00000173981.1
ENSMUST00000173849.1
ENSMUST00000174223.1
selenium binding protein 2
chr3_+_90669063 1.10 ENSMUST00000069927.8
S100 calcium binding protein A8 (calgranulin A)
chr3_-_63964659 1.10 ENSMUST00000161659.1
solute carrier family 33 (acetyl-CoA transporter), member 1
chr5_+_30013141 1.09 ENSMUST00000026845.7
interleukin 6
chr3_-_131272077 1.07 ENSMUST00000029610.8
hydroxyacyl-Coenzyme A dehydrogenase
chr2_-_181581996 1.05 ENSMUST00000057816.8
uridine-cytidine kinase 1-like 1
chr4_-_129227883 1.04 ENSMUST00000106051.1
expressed sequence C77080
chr4_-_137118135 1.03 ENSMUST00000154285.1
predicted gene 13001
chr11_+_114851814 1.03 ENSMUST00000053361.5
ENSMUST00000021071.7
ENSMUST00000136785.1
G protein-coupled receptor, family C, group 5, member C
chr4_+_141239499 1.02 ENSMUST00000141834.2
Rho guanine nucleotide exchange factor (GEF) 19
chr11_+_4236411 1.01 ENSMUST00000075221.2
oncostatin M
chr2_+_76650264 1.00 ENSMUST00000099986.2
deafness, autosomal recessive 59 (human)
chr11_-_69858687 0.99 ENSMUST00000125571.1
tyrosine kinase, non-receptor, 1
chr3_+_129836729 0.98 ENSMUST00000077918.5
complement component factor i
chr2_+_129593195 0.97 ENSMUST00000099113.3
ENSMUST00000103202.3
signal-regulatory protein alpha
chr3_-_63964768 0.97 ENSMUST00000029402.8
solute carrier family 33 (acetyl-CoA transporter), member 1
chr15_-_34356421 0.96 ENSMUST00000179647.1
RIKEN cDNA 9430069I07 gene
chr15_+_89322969 0.94 ENSMUST00000066991.5
adrenomedullin 2
chr14_+_65970610 0.91 ENSMUST00000127387.1
clusterin
chr2_-_150362708 0.90 ENSMUST00000051153.5
RIKEN cDNA 3300002I08 gene
chr11_-_94601862 0.90 ENSMUST00000103164.3
acyl-CoA synthetase family member 2
chr14_+_65970804 0.89 ENSMUST00000138191.1
clusterin
chr6_-_83033422 0.87 ENSMUST00000089651.5
docking protein 1
chr14_+_65971164 0.87 ENSMUST00000144619.1
clusterin
chr6_+_43265582 0.86 ENSMUST00000031750.7
Rho guanine nucleotide exchange factor (GEF) 5
chr2_-_104742802 0.85 ENSMUST00000028595.7
DEP domain containing 7
chr19_-_6840590 0.85 ENSMUST00000170516.2
ENSMUST00000025903.5
ribosomal protein S6 kinase, polypeptide 4
chr2_+_104095796 0.84 ENSMUST00000040423.5
ENSMUST00000168176.1
CD59a antigen
chr2_-_165234689 0.84 ENSMUST00000065438.6
cadherin 22
chr14_+_65971049 0.84 ENSMUST00000128539.1
clusterin
chr4_+_45965327 0.83 ENSMUST00000107777.2
tudor domain containing 7
chr11_-_82764303 0.82 ENSMUST00000021040.3
ENSMUST00000100722.4
chaperonin containing Tcp1, subunit 6b (zeta)
chr2_+_24385313 0.81 ENSMUST00000056641.8
pleckstrin and Sec7 domain containing 4
chr4_+_123787857 0.81 ENSMUST00000053202.5
rhomboid, veinlet-like 2 (Drosophila)
chr17_+_36942910 0.81 ENSMUST00000040498.5
ring finger protein 39
chr6_-_34177048 0.81 ENSMUST00000019143.8
solute carrier family 35, member B4
chr1_-_75278345 0.81 ENSMUST00000039534.4
regulated endocrine-specific protein 18
chr1_-_144004142 0.81 ENSMUST00000127206.1
regulator of G-protein signaling 2
chr10_+_81628570 0.80 ENSMUST00000153573.1
ENSMUST00000119336.1
ankyrin repeat domain 24
chr4_-_45532470 0.80 ENSMUST00000147448.1
src homology 2 domain-containing transforming protein B
chr15_+_80671829 0.79 ENSMUST00000023044.5
family with sequence similarity 83, member F
chr3_+_135826075 0.78 ENSMUST00000029810.5
solute carrier family 39 (metal ion transporter), member 8
chr19_+_6164433 0.76 ENSMUST00000045042.7
basic leucine zipper transcription factor, ATF-like 2
chr3_+_89245952 0.76 ENSMUST00000040888.5
keratinocyte associated protein 2
chr5_-_38480131 0.76 ENSMUST00000143758.1
ENSMUST00000067886.5
solute carrier family 2 (facilitated glucose transporter), member 9
chr4_+_41755210 0.76 ENSMUST00000108038.1
ENSMUST00000084695.4
galactose-1-phosphate uridyl transferase
chr4_-_129614254 0.75 ENSMUST00000106037.2
ENSMUST00000179209.1
doublecortin domain containing 2b
chr12_+_95692212 0.75 ENSMUST00000057324.3
fibronectin leucine rich transmembrane protein 2
chr1_-_126830786 0.74 ENSMUST00000162646.1
NCK-associated protein 5
chrX_+_73228272 0.74 ENSMUST00000105111.2
factor 8-associated gene A
chr5_-_137502402 0.74 ENSMUST00000111035.1
ENSMUST00000031728.4
processing of precursor 7, ribonuclease P family, (S. cerevisiae)
chr6_+_78425973 0.73 ENSMUST00000079926.5
regenerating islet-derived 1
chr15_-_78468620 0.72 ENSMUST00000017086.3
transmembrane serine protease 6
chr10_-_89533550 0.70 ENSMUST00000105297.1
nuclear receptor subfamily 1, group H, member 4
chr14_-_50893255 0.70 ENSMUST00000164415.1
kelch-like 33
chr4_-_43454600 0.70 ENSMUST00000098105.3
ENSMUST00000098104.3
ENSMUST00000030179.4
CD72 antigen
chr11_+_97050594 0.69 ENSMUST00000090020.5
oxysterol binding protein-like 7
chr3_+_27317028 0.69 ENSMUST00000046383.5
ENSMUST00000174840.1
tumor necrosis factor (ligand) superfamily, member 10
chr3_-_90389884 0.68 ENSMUST00000029541.5
solute carrier family 27 (fatty acid transporter), member 3
chr10_+_75571522 0.67 ENSMUST00000143226.1
ENSMUST00000124259.1
gamma-glutamyltransferase 1
chr5_-_53707532 0.67 ENSMUST00000031093.3
cholecystokinin A receptor
chr9_-_119339989 0.66 ENSMUST00000035092.6
myeloid differentiation primary response gene 88
chr13_+_55369732 0.65 ENSMUST00000063771.7
regulator of G-protein signaling 14
chr17_+_24470393 0.65 ENSMUST00000053024.6
phosphoglycolate phosphatase
chr7_+_78913765 0.64 ENSMUST00000038142.8
interferon-stimulated protein
chr11_+_78322965 0.63 ENSMUST00000017534.8
aldolase C, fructose-bisphosphate
chr4_-_123750236 0.63 ENSMUST00000102636.3
akirin 1
chr3_+_135825648 0.62 ENSMUST00000180196.1
solute carrier family 39 (metal ion transporter), member 8
chr11_-_96747419 0.62 ENSMUST00000181758.1
RIKEN cDNA 2010300F17 gene
chr3_-_146812951 0.62 ENSMUST00000102515.3
protein kinase, cAMP dependent, catalytic, beta
chr11_+_97050811 0.61 ENSMUST00000168565.1
oxysterol binding protein-like 7
chr8_-_67818284 0.61 ENSMUST00000120071.1
pleckstrin and Sec7 domain containing 3
chr3_+_103575275 0.61 ENSMUST00000090697.4
synaptotagmin VI
chr19_-_5924797 0.61 ENSMUST00000055458.4
CDC42 effector protein (Rho GTPase binding) 2
chr6_+_143167210 0.60 ENSMUST00000032413.4
ethanolamine kinase 1
chr12_-_31950535 0.60 ENSMUST00000172314.2
high mobility group box transcription factor 1
chr5_+_16553488 0.60 ENSMUST00000030683.3
hepatocyte growth factor
chr11_-_120713725 0.60 ENSMUST00000106154.1
ENSMUST00000106155.3
ENSMUST00000055424.6
ENSMUST00000026137.7
stimulated by retinoic acid 13
chr18_-_80986578 0.59 ENSMUST00000057950.7
sal-like 3 (Drosophila)
chr6_-_33060256 0.59 ENSMUST00000066379.4
coiled-coil-helix-coiled-coil-helix domain containing 3
chr11_+_62648811 0.59 ENSMUST00000127589.1
ENSMUST00000155759.2
membrane magnesium transporter 2
chr1_-_37865040 0.59 ENSMUST00000041815.8
testis specific 10
chr4_-_142239356 0.59 ENSMUST00000036476.3
kazrin, periplakin interacting protein
chr6_-_83656082 0.59 ENSMUST00000014686.2
C-type lectin domain family 4, member f
chr1_+_162477680 0.58 ENSMUST00000159707.1
predicted gene 10176
chr7_-_126625676 0.58 ENSMUST00000032961.3
nuclear protein transcription regulator 1
chr17_-_57247632 0.57 ENSMUST00000005975.6
G protein-coupled receptor 108
chr3_-_57847478 0.57 ENSMUST00000120289.1
ENSMUST00000066882.8
profilin 2
chr5_-_115158169 0.57 ENSMUST00000053271.5
ENSMUST00000112121.1
malectin
chr11_-_102296618 0.56 ENSMUST00000107132.2
ENSMUST00000073234.2
ataxin 7-like 3
chr10_+_62920648 0.56 ENSMUST00000144459.1
solute carrier family 25 (mitochondrial carrier, Graves disease autoantigen), member 16
chr1_-_162478004 0.56 ENSMUST00000086074.5
ENSMUST00000070330.7
dynamin 3
chr1_+_92973113 0.56 ENSMUST00000027489.7
G protein-coupled receptor 35
chr5_-_150594493 0.56 ENSMUST00000016279.7
NEDD4 binding protein 2-like 1
chr19_+_4594312 0.55 ENSMUST00000113825.2
pyruvate carboxylase
chr2_-_26604267 0.55 ENSMUST00000028286.5
1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta)
chr6_+_97991776 0.55 ENSMUST00000043628.6
microphthalmia-associated transcription factor
chr9_-_107289847 0.54 ENSMUST00000035194.2
mitogen-activated protein kinase-activated protein kinase 3
chr3_+_103576081 0.54 ENSMUST00000183637.1
ENSMUST00000117221.2
ENSMUST00000118117.1
ENSMUST00000118563.2
synaptotagmin VI
chr3_-_89393294 0.54 ENSMUST00000142119.1
ENSMUST00000029677.8
ENSMUST00000148361.1
zinc finger and BTB domain containing 7B
chr17_-_27728889 0.54 ENSMUST00000167489.1
ENSMUST00000138970.1
ENSMUST00000114870.1
ENSMUST00000025054.2
SAM pointed domain containing ets transcription factor
chr6_+_4600840 0.54 ENSMUST00000015333.5
CAS1 domain containing 1
chr19_-_57118981 0.54 ENSMUST00000111528.1
ENSMUST00000111529.1
ENSMUST00000104902.2
actin-binding LIM protein 1
chr5_+_135887905 0.53 ENSMUST00000005077.6
heat shock protein 1
chr4_-_115647709 0.53 ENSMUST00000102707.3
cytochrome P450, family 4, subfamily b, polypeptide 1
chr8_-_84197667 0.53 ENSMUST00000181282.1
predicted gene, 26887
chr3_-_89393629 0.52 ENSMUST00000124783.1
ENSMUST00000126027.1
zinc finger and BTB domain containing 7B
chr11_-_96747405 0.52 ENSMUST00000180492.1
RIKEN cDNA 2010300F17 gene
chr4_-_43454563 0.52 ENSMUST00000107926.1
CD72 antigen
chr19_+_4097392 0.52 ENSMUST00000174514.1
ENSMUST00000174149.1
CDK2-associated protein 2
chr11_+_62648656 0.52 ENSMUST00000062860.4
membrane magnesium transporter 2
chr16_-_8672145 0.51 ENSMUST00000008537.8
calcium regulated heat stable protein 1
chr17_+_32621319 0.50 ENSMUST00000077639.5
predicted gene 9705
chr4_-_43454582 0.50 ENSMUST00000107925.1
CD72 antigen
chr4_-_45530330 0.49 ENSMUST00000061986.5
src homology 2 domain-containing transforming protein B
chr13_+_29016267 0.49 ENSMUST00000140415.1
RIKEN cDNA A330102I10 gene
chr8_+_22757744 0.49 ENSMUST00000033941.5
plasminogen activator, tissue
chr5_-_100719675 0.49 ENSMUST00000112908.1
ENSMUST00000045617.8
heparanase
chr13_+_74639866 0.49 ENSMUST00000169114.1
endoplasmic reticulum aminopeptidase 1
chr4_-_129239165 0.49 ENSMUST00000097873.3
expressed sequence C77080
chr6_+_4601124 0.48 ENSMUST00000181734.1
ENSMUST00000141359.1
CAS1 domain containing 1
chr1_-_87573825 0.48 ENSMUST00000068681.5
neuronal guanine nucleotide exchange factor
chr11_+_102885160 0.48 ENSMUST00000100369.3
family with sequence similarity 187, member A
chr3_+_41742615 0.48 ENSMUST00000146165.1
ENSMUST00000119572.1
ENSMUST00000108065.2
ENSMUST00000120167.1
ENSMUST00000026867.7
ENSMUST00000026868.7
DNA segment, Chr 3, ERATO Doi 751, expressed
chr10_-_75822521 0.48 ENSMUST00000160211.1
glutathione S-transferase, theta 4
chr11_+_115877497 0.48 ENSMUST00000144032.1
myosin XVB
chr4_-_156059414 0.47 ENSMUST00000184348.1
tubulin tyrosine ligase-like family, member 10
chr8_-_86580664 0.47 ENSMUST00000131423.1
ENSMUST00000152438.1
ATP-binding cassette, sub-family C (CFTR/MRP), member 12
chr19_-_46672883 0.47 ENSMUST00000026012.7
cytochrome P450, family 17, subfamily a, polypeptide 1
chr15_-_98296083 0.47 ENSMUST00000169721.1
ENSMUST00000023722.5
zinc finger protein 641
chr14_+_79481164 0.46 ENSMUST00000040131.5
E74-like factor 1
chr8_+_72161101 0.46 ENSMUST00000003121.8
RAB8A, member RAS oncogene family
chr6_-_33060172 0.46 ENSMUST00000115091.1
ENSMUST00000127666.1
coiled-coil-helix-coiled-coil-helix domain containing 3
chr1_+_93006328 0.46 ENSMUST00000059676.4
aquaporin 12
chr2_+_11642786 0.45 ENSMUST00000028111.4
interleukin 2 receptor, alpha chain
chr8_-_67818218 0.45 ENSMUST00000059374.4
pleckstrin and Sec7 domain containing 3
chr4_-_141239453 0.44 ENSMUST00000168138.1
RIKEN cDNA C630004L07 gene
chr3_-_116423930 0.44 ENSMUST00000106491.2
CDC14 cell division cycle 14A
chr5_-_116288944 0.43 ENSMUST00000086483.3
coiled-coil domain containing 60
chr10_-_81364846 0.43 ENSMUST00000131736.1
RIKEN cDNA 4930404N11 gene
chr13_-_55415166 0.43 ENSMUST00000054146.3
profilin 3
chr1_-_5019342 0.43 ENSMUST00000002533.8
regulator of G-protein signaling 20
chr2_+_164832881 0.43 ENSMUST00000103092.1
ENSMUST00000151493.1
ENSMUST00000127650.1
cathepsin A

Network of associatons between targets according to the STRING database.

First level regulatory network of Nfic_Nfib

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 5.7 GO:0018992 germ-line sex determination(GO:0018992)
0.9 3.8 GO:0010286 heat acclimation(GO:0010286)
0.8 3.3 GO:0060584 ovarian follicle rupture(GO:0001543) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.6 3.5 GO:1902847 regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.6 1.7 GO:0051794 regulation of catagen(GO:0051794)
0.5 2.6 GO:0000103 sulfate assimilation(GO:0000103)
0.5 1.4 GO:0006583 melanin biosynthetic process from tyrosine(GO:0006583)
0.4 1.3 GO:0034165 positive regulation of toll-like receptor 9 signaling pathway(GO:0034165)
0.4 1.3 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344) formin-nucleated actin cable assembly(GO:0070649)
0.4 1.1 GO:0070488 neutrophil aggregation(GO:0070488)
0.4 1.1 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.3 3.1 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.3 1.3 GO:1902303 negative regulation of potassium ion export(GO:1902303)
0.3 2.2 GO:1903142 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.3 1.4 GO:0050915 sensory perception of sour taste(GO:0050915)
0.3 3.4 GO:0070166 enamel mineralization(GO:0070166)
0.3 0.8 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.3 0.8 GO:0090481 pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.3 1.1 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.3 1.6 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.3 2.3 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.3 0.8 GO:0006011 UDP-glucose metabolic process(GO:0006011)
0.2 0.5 GO:0060278 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.2 0.7 GO:0034971 histone H3-R17 methylation(GO:0034971)
0.2 1.2 GO:0007262 STAT protein import into nucleus(GO:0007262)
0.2 1.1 GO:1903059 regulation of protein lipidation(GO:1903059)
0.2 0.7 GO:0002023 reduction of food intake in response to dietary excess(GO:0002023)
0.2 0.9 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
0.2 1.1 GO:0008655 pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.2 1.0 GO:1900085 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
0.2 0.8 GO:0044565 dendritic cell proliferation(GO:0044565)
0.2 1.0 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.2 1.2 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
0.2 1.0 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.2 1.0 GO:0015691 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.2 0.6 GO:0002591 positive regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002591) peptide antigen transport(GO:0046968)
0.2 0.8 GO:0007113 endomitotic cell cycle(GO:0007113) thrombopoietin-mediated signaling pathway(GO:0038163) positive regulation of male germ cell proliferation(GO:2000256)
0.2 0.6 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.2 0.7 GO:0035279 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.2 5.6 GO:0006910 phagocytosis, recognition(GO:0006910)
0.2 0.7 GO:0072566 chemokine (C-X-C motif) ligand 1 production(GO:0072566) regulation of chemokine (C-X-C motif) ligand 1 production(GO:2000338)
0.2 0.5 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.2 1.1 GO:0015675 nickel cation transport(GO:0015675)
0.2 0.5 GO:0019085 early viral transcription(GO:0019085)
0.1 0.4 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.1 1.5 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.1 0.1 GO:0042488 positive regulation of odontogenesis of dentin-containing tooth(GO:0042488)
0.1 0.6 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.1 1.8 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.1 0.8 GO:1904715 negative regulation of chaperone-mediated autophagy(GO:1904715)
0.1 0.8 GO:0010519 negative regulation of phospholipase activity(GO:0010519)
0.1 0.6 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.1 0.4 GO:0034147 regulation of granuloma formation(GO:0002631) negative regulation of granuloma formation(GO:0002632) regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070425) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070433) tolerance induction to lipopolysaccharide(GO:0072573)
0.1 0.4 GO:1904207 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.1 0.8 GO:0001969 activation of membrane attack complex(GO:0001905) regulation of activation of membrane attack complex(GO:0001969)
0.1 0.3 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.1 0.2 GO:1900369 negative regulation of RNA interference(GO:1900369)
0.1 1.1 GO:0071397 cellular response to cholesterol(GO:0071397)
0.1 0.5 GO:0042738 exogenous drug catabolic process(GO:0042738)
0.1 0.3 GO:0006114 glycerol biosynthetic process(GO:0006114)
0.1 0.3 GO:0003195 tricuspid valve formation(GO:0003195)
0.1 0.4 GO:0006566 threonine metabolic process(GO:0006566)
0.1 0.6 GO:1902947 regulation of tau-protein kinase activity(GO:1902947)
0.1 0.3 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.1 1.9 GO:0046697 decidualization(GO:0046697)
0.1 0.4 GO:0007525 somatic muscle development(GO:0007525)
0.1 1.5 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.1 0.9 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.1 1.1 GO:0060290 transdifferentiation(GO:0060290)
0.1 0.8 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.1 0.6 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.1 0.3 GO:0060842 arterial endothelial cell differentiation(GO:0060842) negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000820)
0.1 0.5 GO:0044351 macropinocytosis(GO:0044351)
0.1 1.0 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.1 0.8 GO:0038033 positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway(GO:0038033)
0.1 1.4 GO:0046415 urate metabolic process(GO:0046415)
0.1 0.4 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.1 1.6 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.1 0.7 GO:1901748 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.1 0.7 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.1 0.2 GO:0010046 response to mycotoxin(GO:0010046)
0.1 0.2 GO:2000909 regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909)
0.1 0.6 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
0.1 0.5 GO:0018094 protein polyglycylation(GO:0018094)
0.1 1.0 GO:1903818 positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.1 2.0 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.1 0.2 GO:0003245 cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.1 0.3 GO:0006548 histidine catabolic process(GO:0006548)
0.1 3.5 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.1 0.6 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.1 1.1 GO:0060481 lobar bronchus epithelium development(GO:0060481)
0.1 0.4 GO:0002317 plasma cell differentiation(GO:0002317)
0.1 0.3 GO:0006751 glutathione catabolic process(GO:0006751)
0.1 0.4 GO:0043415 positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.1 0.2 GO:1900477 negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter(GO:1900477)
0.1 0.7 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.1 1.1 GO:0042407 cristae formation(GO:0042407)
0.1 0.3 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.1 0.2 GO:2000611 basement membrane disassembly(GO:0034769) positive regulation of thyroid hormone generation(GO:2000611)
0.1 0.3 GO:0010248 establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.1 0.2 GO:0070103 regulation of interleukin-6-mediated signaling pathway(GO:0070103)
0.1 0.3 GO:0015851 nucleobase transport(GO:0015851) pyrimidine nucleobase transport(GO:0015855)
0.1 0.3 GO:0044376 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.1 0.8 GO:0042448 progesterone metabolic process(GO:0042448)
0.1 1.8 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1 0.2 GO:2001054 negative regulation of mesenchymal cell apoptotic process(GO:2001054)
0.1 0.4 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.1 0.2 GO:0003032 detection of oxygen(GO:0003032) cardiac jelly development(GO:1905072)
0.1 1.1 GO:0014823 response to activity(GO:0014823)
0.1 0.5 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.1 0.7 GO:0097264 self proteolysis(GO:0097264)
0.1 0.2 GO:0009405 pathogenesis(GO:0009405)
0.1 0.5 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1 0.2 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.1 0.5 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.1 0.3 GO:0039019 pronephric nephron development(GO:0039019)
0.1 0.5 GO:0044336 canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
0.1 0.5 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.1 0.5 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.6 GO:0010745 negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.0 0.6 GO:0051132 NK T cell activation(GO:0051132)
0.0 0.6 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.3 GO:0045343 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343) positive regulation of MHC class I biosynthetic process(GO:0045345)
0.0 0.5 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.0 0.1 GO:2001205 negative regulation of osteoclast development(GO:2001205)
0.0 0.3 GO:0055093 response to hyperoxia(GO:0055093) cellular response to hyperoxia(GO:0071455)
0.0 0.8 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.0 0.8 GO:0018195 peptidyl-arginine modification(GO:0018195)
0.0 0.8 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.6 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.0 0.3 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.0 0.2 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.0 0.3 GO:0032264 IMP salvage(GO:0032264)
0.0 0.2 GO:0060709 glycogen cell differentiation involved in embryonic placenta development(GO:0060709)
0.0 0.4 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.0 1.0 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.6 GO:2000194 regulation of female gonad development(GO:2000194)
0.0 0.3 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
0.0 0.3 GO:0033689 negative regulation of osteoblast proliferation(GO:0033689)
0.0 0.3 GO:0019336 phenol-containing compound catabolic process(GO:0019336) retinal cone cell development(GO:0046549)
0.0 0.2 GO:0048014 Tie signaling pathway(GO:0048014)
0.0 0.4 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 0.1 GO:0001743 optic placode formation(GO:0001743)
0.0 0.2 GO:1900147 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.0 0.1 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.0 0.2 GO:1904970 brush border assembly(GO:1904970)
0.0 1.9 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580) negative regulation of small GTPase mediated signal transduction(GO:0051058)
0.0 0.2 GO:0001980 regulation of systemic arterial blood pressure by ischemic conditions(GO:0001980)
0.0 0.7 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.0 0.2 GO:0010993 regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994)
0.0 0.3 GO:0017062 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.1 GO:0035106 angiotensin-mediated drinking behavior(GO:0003051) operant conditioning(GO:0035106)
0.0 1.2 GO:0006458 'de novo' protein folding(GO:0006458)
0.0 0.5 GO:2000035 regulation of stem cell division(GO:2000035)
0.0 0.2 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.6 GO:0031424 keratinization(GO:0031424)
0.0 0.1 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.0 0.8 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.5 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.3 GO:0031937 positive regulation of chromatin silencing(GO:0031937)
0.0 0.2 GO:0070314 G1 to G0 transition(GO:0070314)
0.0 0.2 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.2 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.0 0.2 GO:0071816 maintenance of unfolded protein(GO:0036506) tail-anchored membrane protein insertion into ER membrane(GO:0071816) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.0 0.1 GO:0001830 trophectodermal cell fate commitment(GO:0001830)
0.0 0.1 GO:2000667 positive regulation of interleukin-5 secretion(GO:2000664) positive regulation of interleukin-13 secretion(GO:2000667)
0.0 0.2 GO:0044359 modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.0 0.1 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.0 0.1 GO:0021650 vestibulocochlear nerve formation(GO:0021650)
0.0 0.7 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.0 0.4 GO:0048820 hair follicle maturation(GO:0048820)
0.0 1.6 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.4 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.1 GO:0015825 L-serine transport(GO:0015825)
0.0 0.1 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.0 0.3 GO:0070269 detection of bacterium(GO:0016045) pyroptosis(GO:0070269) detection of other organism(GO:0098543)
0.0 0.9 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.0 GO:0007161 calcium-independent cell-matrix adhesion(GO:0007161)
0.0 0.1 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.0 0.2 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.0 0.3 GO:0048681 negative regulation of axon regeneration(GO:0048681) positive regulation of protein localization to cell surface(GO:2000010)
0.0 0.1 GO:0006689 ganglioside catabolic process(GO:0006689) oligosaccharide catabolic process(GO:0009313)
0.0 0.3 GO:0035428 hexose transmembrane transport(GO:0035428)
0.0 0.1 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.2 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.8 GO:0070830 bicellular tight junction assembly(GO:0070830)
0.0 0.2 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.0 1.2 GO:0030216 keratinocyte differentiation(GO:0030216)
0.0 0.0 GO:0071918 urea transmembrane transport(GO:0071918)
0.0 0.1 GO:0072053 renal inner medulla development(GO:0072053)
0.0 0.2 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.1 GO:0030070 insulin processing(GO:0030070)
0.0 0.4 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.0 GO:0009624 response to nematode(GO:0009624)
0.0 0.2 GO:0006691 leukotriene metabolic process(GO:0006691)
0.0 0.4 GO:0014059 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 0.1 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.2 GO:0071624 positive regulation of granulocyte chemotaxis(GO:0071624)
0.0 0.6 GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189)
0.0 0.3 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.4 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.1 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.0 0.1 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.3 1.1 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.3 3.5 GO:0097418 neurofibrillary tangle(GO:0097418)
0.1 0.6 GO:0098843 postsynaptic endocytic zone(GO:0098843)
0.1 0.8 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.1 0.7 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.1 1.1 GO:0061617 MICOS complex(GO:0061617)
0.1 10.3 GO:0030667 secretory granule membrane(GO:0030667)
0.1 2.9 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 1.7 GO:0045495 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.1 1.1 GO:0072546 ER membrane protein complex(GO:0072546)
0.1 0.3 GO:0097450 astrocyte end-foot(GO:0097450)
0.1 0.6 GO:0042825 TAP complex(GO:0042825)
0.1 0.7 GO:0097512 cardiac myofibril(GO:0097512)
0.1 0.8 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.1 0.7 GO:0042588 zymogen granule(GO:0042588)
0.1 0.2 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.1 0.8 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 1.5 GO:0045095 keratin filament(GO:0045095)
0.0 0.1 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.0 0.6 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.4 GO:0033269 internode region of axon(GO:0033269)
0.0 2.1 GO:0031902 late endosome membrane(GO:0031902)
0.0 0.3 GO:0072557 IPAF inflammasome complex(GO:0072557)
0.0 0.6 GO:0001533 cornified envelope(GO:0001533)
0.0 0.2 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.8 GO:0032433 filopodium tip(GO:0032433)
0.0 0.5 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 0.2 GO:0031933 telomeric heterochromatin(GO:0031933)
0.0 1.4 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.2 GO:0071439 clathrin complex(GO:0071439)
0.0 0.4 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.2 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 0.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.2 GO:0045098 type III intermediate filament(GO:0045098)
0.0 1.0 GO:0015030 Cajal body(GO:0015030)
0.0 0.5 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 1.9 GO:0005811 lipid particle(GO:0005811)
0.0 0.2 GO:0036156 inner dynein arm(GO:0036156)
0.0 3.7 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.3 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.3 GO:0000124 SAGA complex(GO:0000124)
0.0 0.2 GO:0031045 dense core granule(GO:0031045)
0.0 0.2 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.1 GO:0005861 troponin complex(GO:0005861)
0.0 1.0 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.8 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.0 1.0 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.0 0.2 GO:0030057 desmosome(GO:0030057)
0.0 1.7 GO:0001650 fibrillar center(GO:0001650)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.8 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.8 3.3 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733)
0.8 3.3 GO:0031708 endothelin B receptor binding(GO:0031708)
0.5 1.9 GO:0004921 interleukin-11 receptor activity(GO:0004921) interleukin-11 binding(GO:0019970)
0.4 2.2 GO:0070012 oligopeptidase activity(GO:0070012)
0.4 1.2 GO:0019002 GMP binding(GO:0019002)
0.3 2.1 GO:0051185 coenzyme transporter activity(GO:0051185)
0.3 1.0 GO:0005118 sevenless binding(GO:0005118)
0.3 1.5 GO:0031849 olfactory receptor binding(GO:0031849)
0.3 2.2 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.3 1.0 GO:0008859 exoribonuclease II activity(GO:0008859)
0.2 1.2 GO:0008172 S-methyltransferase activity(GO:0008172)
0.2 1.6 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.2 1.3 GO:0000155 phosphorelay sensor kinase activity(GO:0000155) voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.2 2.5 GO:0008430 selenium binding(GO:0008430)
0.2 1.1 GO:0004849 uridine kinase activity(GO:0004849)
0.2 1.0 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.2 0.6 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798)
0.2 0.7 GO:0070976 TIR domain binding(GO:0070976)
0.2 0.6 GO:0008967 phosphoglycolate phosphatase activity(GO:0008967)
0.2 0.6 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.2 1.1 GO:0015099 nickel cation transmembrane transporter activity(GO:0015099)
0.2 0.5 GO:0070737 protein-glycine ligase activity, elongating(GO:0070737)
0.2 0.8 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.1 0.4 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.1 3.5 GO:0051787 misfolded protein binding(GO:0051787)
0.1 0.7 GO:0038181 bile acid receptor activity(GO:0038181)
0.1 1.1 GO:0035662 Toll-like receptor 4 binding(GO:0035662) RAGE receptor binding(GO:0050786)
0.1 0.4 GO:0008732 threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.1 0.3 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.1 1.4 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.1 0.4 GO:0016501 prostacyclin receptor activity(GO:0016501)
0.1 0.2 GO:0008940 nitrate reductase activity(GO:0008940)
0.1 0.6 GO:0046980 peptide antigen-transporting ATPase activity(GO:0015433) tapasin binding(GO:0046980)
0.1 0.8 GO:0005534 galactose binding(GO:0005534)
0.1 1.0 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.1 1.1 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.1 1.1 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 8.7 GO:0045309 protein phosphorylated amino acid binding(GO:0045309)
0.1 1.2 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.1 0.5 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.1 1.0 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.1 3.0 GO:0070566 adenylyltransferase activity(GO:0070566)
0.1 0.3 GO:0035939 microsatellite binding(GO:0035939)
0.1 0.8 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.1 0.6 GO:0001515 opioid peptide activity(GO:0001515)
0.1 0.3 GO:0005333 norepinephrine transmembrane transporter activity(GO:0005333)
0.1 0.3 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.1 3.0 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.1 0.8 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.1 0.3 GO:0050436 microfibril binding(GO:0050436)
0.1 0.8 GO:0070569 uridylyltransferase activity(GO:0070569)
0.1 0.2 GO:0032129 histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969)
0.1 0.2 GO:0003692 left-handed Z-DNA binding(GO:0003692)
0.1 0.2 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.1 0.1 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.1 0.5 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.1 0.6 GO:0009374 biotin binding(GO:0009374)
0.1 0.7 GO:0004526 ribonuclease P activity(GO:0004526)
0.1 0.5 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.1 11.0 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 0.6 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 0.5 GO:0045545 syndecan binding(GO:0045545)
0.1 0.8 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 1.8 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 0.7 GO:0015643 toxic substance binding(GO:0015643)
0.1 0.3 GO:0015254 purine nucleobase transmembrane transporter activity(GO:0005345) pyrimidine nucleobase transmembrane transporter activity(GO:0005350) nucleobase transmembrane transporter activity(GO:0015205) glycerol channel activity(GO:0015254)
0.1 1.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.2 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.4 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.8 GO:0045499 chemorepellent activity(GO:0045499)
0.0 1.0 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.0 1.0 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.3 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.2 GO:0051381 histamine binding(GO:0051381)
0.0 0.2 GO:1990254 keratin filament binding(GO:1990254)
0.0 2.0 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.2 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.1 GO:0004368 glycerol-3-phosphate dehydrogenase activity(GO:0004368) oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.0 0.3 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.7 GO:0016408 C-acyltransferase activity(GO:0016408)
0.0 0.2 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.0 0.4 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.1 GO:0052794 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997) exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 0.3 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.2 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.8 GO:0001848 complement binding(GO:0001848)
0.0 0.2 GO:0030172 troponin C binding(GO:0030172)
0.0 0.4 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.9 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.2 GO:0004920 interleukin-10 receptor activity(GO:0004920)
0.0 1.6 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 1.4 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.4 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.7 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.2 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0 1.0 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.7 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.4 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.4 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 1.3 GO:0032947 protein complex scaffold(GO:0032947)
0.0 0.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.5 GO:0031489 myosin V binding(GO:0031489)
0.0 0.2 GO:0036122 BMP binding(GO:0036122)
0.0 0.5 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.1 GO:0031014 troponin T binding(GO:0031014)
0.0 0.4 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.3 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.0 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.0 0.2 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.3 GO:0005351 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.0 1.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.0 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.6 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.2 GO:0015245 fatty acid transporter activity(GO:0015245)
0.0 0.3 GO:0005123 death receptor binding(GO:0005123)
0.0 0.0 GO:0015166 polyol transmembrane transporter activity(GO:0015166)
0.0 0.1 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.1 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.0 GO:0032190 acrosin binding(GO:0032190)
0.0 0.3 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 0.5 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 2.6 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.4 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.1 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 0.2 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.1 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640)
0.0 0.2 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.5 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.1 4.4 PID IL1 PATHWAY IL1-mediated signaling events
0.1 1.2 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 1.2 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 1.1 ST STAT3 PATHWAY STAT3 Pathway
0.1 1.6 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.1 2.6 PID BCR 5PATHWAY BCR signaling pathway
0.1 1.1 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 3.3 PID ENDOTHELIN PATHWAY Endothelins
0.1 2.9 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 3.1 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.9 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.9 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.7 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 1.1 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.8 PID AURORA A PATHWAY Aurora A signaling
0.0 0.3 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 0.4 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.7 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.2 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.1 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 1.0 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.3 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.3 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.6 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.8 ST FAS SIGNALING PATHWAY Fas Signaling Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 5.6 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.2 2.6 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.2 2.2 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 2.4 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.1 1.1 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 1.1 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 1.3 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 4.1 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.1 3.2 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.1 0.5 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.1 0.9 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.1 1.1 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 0.6 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.1 0.5 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.1 0.4 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.1 0.2 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.1 2.5 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 1.1 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 0.7 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 0.6 REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.0 1.1 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 4.4 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.6 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 1.7 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 1.8 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.9 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.2 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.8 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 1.4 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 1.1 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.6 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.5 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.3 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0 1.3 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 1.3 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.5 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.4 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 3.4 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.3 REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION Genes involved in Cyclin E associated events during G1/S transition
0.0 0.3 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.7 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.8 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.3 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.9 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.3 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.4 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.3 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.3 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.4 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.1 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.1 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.5 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.1 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1