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12D miR HR13_24

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Results for Gata2_Gata1

Z-value: 1.52

Motif logo

Transcription factors associated with Gata2_Gata1

Gene Symbol Gene ID Gene Info
ENSMUSG00000015053.8 GATA binding protein 2
ENSMUSG00000031162.8 GATA binding protein 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Gata1mm10_v2_chrX_-_7967817_7967910-0.323.4e-01Click!
Gata2mm10_v2_chr6_+_88198656_88198675-0.185.9e-01Click!

Activity profile of Gata2_Gata1 motif

Sorted Z-values of Gata2_Gata1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr19_+_58670358 3.66 ENSMUST00000057270.7
pancreatic lipase
chr6_+_30639218 3.24 ENSMUST00000031806.9
carboxypeptidase A1, pancreatic
chr5_+_115466234 2.87 ENSMUST00000145785.1
ENSMUST00000031495.4
ENSMUST00000112071.1
ENSMUST00000125568.1
phospholipase A2, group IB, pancreas
chr3_-_84479418 2.59 ENSMUST00000091002.1
FH2 domain containing 1
chr6_+_30541582 2.55 ENSMUST00000096066.4
carboxypeptidase A2, pancreatic
chr17_-_26199008 2.53 ENSMUST00000142410.1
ENSMUST00000120333.1
ENSMUST00000039113.7
protein disulfide isomerase associated 2
chr4_+_40920047 2.45 ENSMUST00000030122.4
serine peptidase inhibitor, Kazal type 4
chr6_+_41302265 2.35 ENSMUST00000031913.4
trypsin 4
chr6_-_136922169 2.32 ENSMUST00000032343.6
endoplasmic reticulum protein 27
chr8_+_84701430 2.25 ENSMUST00000037165.4
lymphoblastomic leukemia 1
chr2_+_164403194 2.15 ENSMUST00000017151.1
recombination signal binding protein for immunoglobulin kappa J region-like
chr14_+_30886476 2.13 ENSMUST00000006703.6
ENSMUST00000078490.5
ENSMUST00000120269.2
inter alpha-trypsin inhibitor, heavy chain 4
chr6_+_41392356 2.09 ENSMUST00000049079.7
predicted gene 5771
chr3_+_135825788 2.05 ENSMUST00000167390.1
solute carrier family 39 (metal ion transporter), member 8
chr4_-_137409777 1.89 ENSMUST00000024200.6
predicted gene 13011
chr4_-_137430517 1.86 ENSMUST00000102522.4
chymotrypsin-like elastase family, member 3B
chr7_-_100662315 1.83 ENSMUST00000151123.1
ENSMUST00000107047.2
pleckstrin homology domain containing, family B (evectins) member 1
chr17_-_28560704 1.82 ENSMUST00000114785.1
ENSMUST00000025062.3
colipase, pancreatic
chr11_+_70505244 1.74 ENSMUST00000019063.2
transmembrane 4 superfamily member 5
chr7_-_100662414 1.66 ENSMUST00000079176.6
pleckstrin homology domain containing, family B (evectins) member 1
chrX_+_140907602 1.62 ENSMUST00000033806.4
V-set and immunoglobulin domain containing 1
chr14_+_30886521 1.61 ENSMUST00000168782.1
inter alpha-trypsin inhibitor, heavy chain 4
chr3_+_135826075 1.49 ENSMUST00000029810.5
solute carrier family 39 (metal ion transporter), member 8
chr17_-_31144271 1.33 ENSMUST00000024826.7
trefoil factor 2 (spasmolytic protein 1)
chr6_+_41458923 1.31 ENSMUST00000031910.7
protease, serine, 1 (trypsin 1)
chr7_+_28540863 1.29 ENSMUST00000119180.2
syncollin
chr1_-_162866502 1.23 ENSMUST00000046049.7
flavin containing monooxygenase 1
chr4_+_41760454 1.21 ENSMUST00000108040.1
interleukin 11 receptor, alpha chain 1
chr3_+_106113229 1.16 ENSMUST00000079132.5
ENSMUST00000139086.1
chitinase, acidic
chr13_+_38345716 1.10 ENSMUST00000171970.1
bone morphogenetic protein 6
chr19_-_6015152 1.09 ENSMUST00000025891.8
calpain 1
chr4_+_134864536 1.07 ENSMUST00000030627.7
Rh blood group, D antigen
chr8_-_110039330 1.07 ENSMUST00000109222.2
carbohydrate (chondroitin 6/keratan) sulfotransferase 4
chr2_+_169633517 1.06 ENSMUST00000109157.1
teashirt zinc finger family member 2
chr3_-_75270073 1.04 ENSMUST00000039047.4
serine (or cysteine) peptidase inhibitor, clade I, member 2
chr19_-_11081088 1.03 ENSMUST00000025636.6
membrane-spanning 4-domains, subfamily A, member 8A
chr14_+_33941021 1.02 ENSMUST00000100720.1
growth differentiation factor 2
chr2_+_169632996 1.01 ENSMUST00000109159.2
teashirt zinc finger family member 2
chr19_-_6015769 0.99 ENSMUST00000164843.1
calpain 1
chr16_+_45093611 0.98 ENSMUST00000099498.2
coiled-coil domain containing 80
chr15_-_103251465 0.97 ENSMUST00000133600.1
ENSMUST00000134554.1
ENSMUST00000156927.1
ENSMUST00000149111.1
ENSMUST00000132836.1
nuclear factor, erythroid derived 2
chr7_-_119459266 0.97 ENSMUST00000033255.5
glycoprotein 2 (zymogen granule membrane)
chr16_+_45094036 0.94 ENSMUST00000061050.5
coiled-coil domain containing 80
chr6_-_41314700 0.91 ENSMUST00000064324.5
trypsin 5
chr16_-_44016387 0.88 ENSMUST00000036174.3
GRAM domain containing 1C
chr8_+_13037802 0.87 ENSMUST00000152034.1
ENSMUST00000128418.1
coagulation factor X
chr10_+_53337686 0.86 ENSMUST00000046221.6
ENSMUST00000163319.1
phospholamban
chrX_-_107403295 0.86 ENSMUST00000033591.5
integral membrane protein 2A
chr4_+_133553370 0.83 ENSMUST00000042706.2
nuclear receptor subfamily 0, group B, member 2
chr17_-_84682932 0.81 ENSMUST00000066175.3
ATP-binding cassette, sub-family G (WHITE), member 5
chr7_-_4522794 0.78 ENSMUST00000140424.1
troponin I, cardiac 3
chr7_+_123462274 0.77 ENSMUST00000033023.3
aquaporin 8
chr10_-_115185015 0.77 ENSMUST00000006949.8
tryptophan hydroxylase 2
chr14_+_55560904 0.75 ENSMUST00000072530.4
ENSMUST00000128490.1
DDB1 and CUL4 associated factor 11
chr17_-_35066170 0.71 ENSMUST00000174190.1
ENSMUST00000097337.1
expressed sequence AU023871
chr2_-_103303179 0.68 ENSMUST00000090475.3
ets homologous factor
chr14_+_55561060 0.67 ENSMUST00000117701.1
DDB1 and CUL4 associated factor 11
chr8_+_13037308 0.67 ENSMUST00000063820.5
ENSMUST00000033821.4
coagulation factor X
chr17_-_35046539 0.66 ENSMUST00000007250.7
mutS homolog 5 (E. coli)
chr3_-_144819494 0.66 ENSMUST00000029929.7
chloride channel calcium activated 2
chr2_-_103303158 0.64 ENSMUST00000111176.2
ets homologous factor
chr3_+_28697901 0.64 ENSMUST00000029240.7
solute carrier family 2 (facilitated glucose transporter), member 2
chr3_+_122895072 0.63 ENSMUST00000023820.5
fatty acid binding protein 2, intestinal
chr19_+_38264761 0.61 ENSMUST00000087252.5
leucine-rich repeat LGI family, member 1
chr5_-_73191848 0.60 ENSMUST00000176910.1
furry homolog-like (Drosophila)
chr10_+_80019621 0.55 ENSMUST00000043311.6
histocompatibility (minor) HA-1
chr4_-_138326234 0.54 ENSMUST00000105817.3
ENSMUST00000030536.6
PTEN induced putative kinase 1
chr16_+_58670208 0.53 ENSMUST00000060077.5
coproporphyrinogen oxidase
chr6_+_17306415 0.52 ENSMUST00000150901.1
caveolin 1, caveolae protein
chr14_+_27000362 0.51 ENSMUST00000035433.8
homeobox gene expressed in ES cells
chr1_-_136960427 0.51 ENSMUST00000027649.7
nuclear receptor subfamily 5, group A, member 2
chr1_+_75507077 0.51 ENSMUST00000037330.4
inhibin alpha
chr13_+_42301270 0.49 ENSMUST00000021796.7
endothelin 1
chr15_-_50890396 0.49 ENSMUST00000185183.1
trichorhinophalangeal syndrome I (human)
chr18_+_76059458 0.49 ENSMUST00000167921.1
zinc finger and BTB domain containing 7C
chr19_-_40187277 0.48 ENSMUST00000051846.6
cytochrome P450, family 2, subfamily c, polypeptide 70
chr11_+_87760533 0.47 ENSMUST00000039627.5
ENSMUST00000100644.3
benzodiazepine receptor associated protein 1
chr11_-_99322943 0.47 ENSMUST00000038004.2
keratin 25
chr2_-_25236787 0.46 ENSMUST00000091318.4
predicted gene 757
chr6_-_31218421 0.46 ENSMUST00000115107.1
cDNA sequence AB041803
chr2_-_77170592 0.44 ENSMUST00000164114.2
ENSMUST00000049544.7
coiled-coil domain containing 141
chr4_-_46404224 0.44 ENSMUST00000107764.2
hemogen
chr10_-_34096507 0.43 ENSMUST00000069125.6
family with sequence similarity 26, member E
chr8_+_105269788 0.42 ENSMUST00000036127.2
ENSMUST00000163734.2
heat shock transcription factor 4
chr17_-_25944932 0.41 ENSMUST00000085027.3
NHL repeat containing 4
chr3_-_59262825 0.41 ENSMUST00000050360.7
purinergic receptor P2Y, G-protein coupled 12
chr4_-_63861326 0.40 ENSMUST00000030047.2
tumor necrosis factor (ligand) superfamily, member 8
chr14_+_55560480 0.40 ENSMUST00000121622.1
ENSMUST00000143431.1
ENSMUST00000150481.1
DDB1 and CUL4 associated factor 11
chr2_-_52558539 0.39 ENSMUST00000102760.3
ENSMUST00000102761.2
calcium channel, voltage-dependent, beta 4 subunit
chr7_-_30856178 0.38 ENSMUST00000094583.1
free fatty acid receptor 3
chr2_+_103957976 0.36 ENSMUST00000156813.1
ENSMUST00000170926.1
LIM domain only 2
chr3_-_102782708 0.34 ENSMUST00000029450.3
ENSMUST00000172026.1
ENSMUST00000170856.1
thyroid stimulating hormone, beta subunit
chr4_-_14621805 0.34 ENSMUST00000042221.7
solute carrier family 26, member 7
chr11_+_67586520 0.34 ENSMUST00000108682.2
growth arrest specific 7
chr2_+_70474923 0.34 ENSMUST00000100043.2
trans-acting transcription factor 5
chr8_+_105269837 0.33 ENSMUST00000172525.1
ENSMUST00000174837.1
ENSMUST00000173859.1
heat shock transcription factor 4
chr11_+_110399115 0.33 ENSMUST00000020949.5
ENSMUST00000100260.1
mitogen-activated protein kinase kinase 6
chr13_+_42709482 0.33 ENSMUST00000066928.5
ENSMUST00000148891.1
phosphatase and actin regulator 1
chr6_-_125380793 0.33 ENSMUST00000042647.6
pleckstrin homology domain containing, family G (with RhoGef domain) member 6
chr15_-_101786458 0.32 ENSMUST00000071104.4
keratin 72
chr2_-_160327494 0.32 ENSMUST00000099127.2
predicted gene 826
chr4_+_150148905 0.29 ENSMUST00000059893.7
solute carrier family 2 (facilitated glucose transporter), member 7
chr7_-_119895446 0.28 ENSMUST00000098080.2
DCN1, defective in cullin neddylation 1, domain containing 3 (S. cerevisiae)
chr13_+_42681513 0.28 ENSMUST00000149235.1
phosphatase and actin regulator 1
chr4_+_145696161 0.27 ENSMUST00000180014.1
predicted gene 13242
chr8_+_105636509 0.27 ENSMUST00000005841.9
CCCTC-binding factor
chr3_+_105904377 0.27 ENSMUST00000000574.1
adenosine A3 receptor
chr6_-_41704339 0.27 ENSMUST00000031899.8
Kell blood group
chr1_+_45311538 0.27 ENSMUST00000087883.6
collagen, type III, alpha 1
chr11_-_116077954 0.26 ENSMUST00000106451.1
ENSMUST00000075036.2
unc-13 homolog D (C. elegans)
chr15_+_80623499 0.26 ENSMUST00000043149.7
GRB2-related adaptor protein 2
chr4_-_82705735 0.25 ENSMUST00000155821.1
nuclear factor I/B
chr3_-_121643485 0.25 ENSMUST00000050571.4
RIKEN cDNA A730020M07 gene
chr7_-_98112618 0.25 ENSMUST00000153657.1
myosin VIIA
chr11_+_95337012 0.24 ENSMUST00000037502.6
family with sequence similarity 117, member A
chr12_+_95692212 0.24 ENSMUST00000057324.3
fibronectin leucine rich transmembrane protein 2
chr16_-_48771956 0.24 ENSMUST00000170861.1
T cell receptor associated transmembrane adaptor 1
chr18_-_78123324 0.24 ENSMUST00000160292.1
ENSMUST00000091813.5
solute carrier family 14 (urea transporter), member 1
chr1_+_135818593 0.24 ENSMUST00000038760.8
ladinin
chr13_-_116309639 0.24 ENSMUST00000036060.6
ISL1 transcription factor, LIM/homeodomain
chr16_-_23520579 0.23 ENSMUST00000089883.5
mannan-binding lectin serine peptidase 1
chr2_-_36104060 0.23 ENSMUST00000112961.3
ENSMUST00000112966.3
LIM homeobox protein 6
chr17_-_85688252 0.23 ENSMUST00000024947.7
ENSMUST00000163568.2
sine oculis-related homeobox 2
chr17_+_84683113 0.23 ENSMUST00000045714.8
ATP-binding cassette, sub-family G (WHITE), member 8
chr11_-_116077606 0.22 ENSMUST00000106450.1
unc-13 homolog D (C. elegans)
chr17_+_84683131 0.22 ENSMUST00000171915.1
ATP-binding cassette, sub-family G (WHITE), member 8
chr10_+_116177217 0.21 ENSMUST00000148731.1
protein tyrosine phosphatase, receptor type, R
chr3_+_79884576 0.21 ENSMUST00000145992.1
family with sequence similarity 198, member B
chr9_+_44379536 0.21 ENSMUST00000161318.1
ENSMUST00000160902.1
hypoxia up-regulated 1
chr10_+_116177351 0.21 ENSMUST00000155606.1
ENSMUST00000128399.1
protein tyrosine phosphatase, receptor type, R
chr4_+_135728116 0.20 ENSMUST00000102546.3
interleukin 22 receptor, alpha 1
chrX_+_38316177 0.19 ENSMUST00000016471.2
ENSMUST00000115134.1
ATPase, (Na+)/K+ transporting, beta 4 polypeptide
chr9_+_44379490 0.19 ENSMUST00000066601.6
hypoxia up-regulated 1
chr11_-_26591729 0.19 ENSMUST00000109504.1
vaccinia related kinase 2
chr11_-_116077927 0.19 ENSMUST00000156545.1
unc-13 homolog D (C. elegans)
chr10_-_14718191 0.18 ENSMUST00000020016.4
gap junction protein, epsilon 1
chr13_-_73700721 0.18 ENSMUST00000022048.5
solute carrier family 6 (neurotransmitter transporter), member 19
chr3_+_79884931 0.18 ENSMUST00000135021.1
family with sequence similarity 198, member B
chr7_-_80403315 0.18 ENSMUST00000147150.1
furin (paired basic amino acid cleaving enzyme)
chr7_+_45413657 0.18 ENSMUST00000058879.6
neurotrophin 5
chr14_-_55560340 0.18 ENSMUST00000066106.3
RIKEN cDNA A730061H03 gene
chr18_+_57142782 0.17 ENSMUST00000139892.1
multiple EGF-like-domains 10
chr11_+_90030295 0.17 ENSMUST00000092788.3
transmembrane protein 100
chr2_-_77170534 0.16 ENSMUST00000111833.2
coiled-coil domain containing 141
chr3_+_3634145 0.16 ENSMUST00000108394.1
hepatocyte nuclear factor 4, gamma
chrX_+_73757069 0.16 ENSMUST00000002079.6
plexin B3
chr13_-_91388079 0.16 ENSMUST00000181054.1
RIKEN cDNA A830009L08 gene
chr11_-_116077562 0.15 ENSMUST00000174822.1
unc-13 homolog D (C. elegans)
chr18_+_7869159 0.15 ENSMUST00000170932.1
ENSMUST00000167020.1
WW domain containing adaptor with coiled-coil
chr6_+_115422040 0.15 ENSMUST00000000450.3
peroxisome proliferator activated receptor gamma
chr11_+_118428203 0.15 ENSMUST00000124861.1
C1q and tumor necrosis factor related protein 1
chr11_-_102469839 0.14 ENSMUST00000103086.3
integrin alpha 2b
chr11_-_99351086 0.14 ENSMUST00000017732.2
keratin 27
chr6_-_71632897 0.14 ENSMUST00000065509.4
lysine (K)-specific demethylase 3A
chr11_+_97801917 0.14 ENSMUST00000127033.2
LIM and SH3 protein 1
chr14_-_68533689 0.14 ENSMUST00000022640.7
a disintegrin and metallopeptidase domain 7
chr4_+_56740070 0.14 ENSMUST00000181745.1
predicted gene, 26657
chr8_-_85365317 0.14 ENSMUST00000034133.7
myosin light chain kinase 3
chr2_+_69135799 0.14 ENSMUST00000041865.7
nitric oxide synthase trafficker
chr10_+_5593718 0.13 ENSMUST00000051809.8
myc target 1
chr1_+_180942500 0.13 ENSMUST00000159436.1
transmembrane protein 63a
chrX_+_10252305 0.13 ENSMUST00000049910.6
ornithine transcarbamylase
chr1_+_40429563 0.13 ENSMUST00000174335.1
interleukin 1 receptor-like 1
chr19_-_37176055 0.13 ENSMUST00000142973.1
ENSMUST00000154376.1
cytoplasmic polyadenylation element binding protein 3
chr6_+_125552948 0.13 ENSMUST00000112254.1
ENSMUST00000112253.1
ENSMUST00000001995.7
Von Willebrand factor homolog
chr6_-_147087023 0.12 ENSMUST00000100780.2
MANSC domain containing 4
chr10_-_83648631 0.12 ENSMUST00000146876.2
ENSMUST00000176294.1
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2
chr12_-_25096080 0.11 ENSMUST00000020974.6
inhibitor of DNA binding 2
chrX_+_99975570 0.11 ENSMUST00000113779.1
ENSMUST00000113776.1
ENSMUST00000113775.1
ENSMUST00000113780.1
ENSMUST00000113778.1
ENSMUST00000113781.1
ENSMUST00000113783.1
ENSMUST00000071453.2
ENSMUST00000113777.1
ectodysplasin-A
chr6_-_138079916 0.11 ENSMUST00000171804.1
solute carrier family 15, member 5
chr8_+_105131800 0.10 ENSMUST00000161289.1
carboxylesterase 4A
chr11_+_118428493 0.10 ENSMUST00000017590.2
C1q and tumor necrosis factor related protein 1
chr14_-_64455903 0.10 ENSMUST00000067927.7
methionine sulfoxide reductase A
chr4_+_117096049 0.10 ENSMUST00000030443.5
patched homolog 2
chr2_+_32621750 0.10 ENSMUST00000113278.2
adenylate kinase 1
chr2_-_121037048 0.10 ENSMUST00000102490.3
erythrocyte protein band 4.2
chr16_-_64786321 0.10 ENSMUST00000052588.4
zinc finger protein 654
chr6_-_136941887 0.10 ENSMUST00000111891.1
Rho, GDP dissociation inhibitor (GDI) beta
chr4_+_124802543 0.10 ENSMUST00000138807.1
ENSMUST00000030723.2
ENSMUST00000175875.1
metal response element binding transcription factor 1
chr2_-_60722636 0.09 ENSMUST00000028348.2
ENSMUST00000112517.1
integrin beta 6
chr11_-_86357570 0.09 ENSMUST00000043624.8
mediator complex subunit 13
chr6_-_136941694 0.09 ENSMUST00000032344.5
Rho, GDP dissociation inhibitor (GDI) beta
chr16_-_29544852 0.08 ENSMUST00000039090.8
ATPase type 13A4
chr3_-_30013156 0.08 ENSMUST00000172694.1
MDS1 and EVI1 complex locus
chr5_+_42067960 0.08 ENSMUST00000087332.4
predicted gene 16223
chr9_-_77251871 0.08 ENSMUST00000183955.1
muscular LMNA-interacting protein
chr6_-_122856151 0.07 ENSMUST00000042081.8
complement component 3a receptor 1
chr3_-_88000350 0.07 ENSMUST00000090971.5
brevican
chr10_-_26078987 0.07 ENSMUST00000066049.6
transmembrane protein 200A
chr8_-_85380964 0.07 ENSMUST00000122452.1
myosin light chain kinase 3
chr3_-_30013388 0.07 ENSMUST00000108270.3
MDS1 and EVI1 complex locus
chr9_-_77251829 0.07 ENSMUST00000184322.1
ENSMUST00000184316.1
muscular LMNA-interacting protein
chr6_+_17463927 0.06 ENSMUST00000115442.1
met proto-oncogene
chr10_+_63457505 0.06 ENSMUST00000105440.1
catenin (cadherin associated protein), alpha 3
chr6_-_136941494 0.06 ENSMUST00000111892.1
Rho, GDP dissociation inhibitor (GDI) beta
chr16_+_25801907 0.05 ENSMUST00000040231.6
ENSMUST00000115306.1
ENSMUST00000115304.1
ENSMUST00000115305.1
transformation related protein 63
chr10_+_90576708 0.05 ENSMUST00000182430.1
ENSMUST00000182960.1
ENSMUST00000182045.1
ENSMUST00000182083.1
ankyrin repeat and sterile alpha motif domain containing 1B
chr10_+_90576777 0.05 ENSMUST00000183136.1
ENSMUST00000182595.1
ankyrin repeat and sterile alpha motif domain containing 1B
chr11_-_5898771 0.04 ENSMUST00000102921.3
myosin, light polypeptide 7, regulatory
chr5_+_24364804 0.04 ENSMUST00000030834.4
ENSMUST00000115090.1
nitric oxide synthase 3, endothelial cell

Network of associatons between targets according to the STRING database.

First level regulatory network of Gata2_Gata1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 2.9 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.4 1.3 GO:0060752 negative regulation of intestinal phytosterol absorption(GO:0010949) negative regulation of intestinal cholesterol absorption(GO:0045796) intestinal phytosterol absorption(GO:0060752) negative regulation of intestinal lipid absorption(GO:1904730)
0.4 1.1 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.4 3.5 GO:0070574 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.3 2.2 GO:0001955 blood vessel maturation(GO:0001955)
0.2 1.3 GO:0060455 negative regulation of gastric acid secretion(GO:0060455)
0.2 1.1 GO:0060586 multicellular organismal iron ion homeostasis(GO:0060586)
0.2 1.0 GO:0002386 immune response in mucosal-associated lymphoid tissue(GO:0002386)
0.2 2.1 GO:0097264 self proteolysis(GO:0097264)
0.1 0.9 GO:0002317 plasma cell differentiation(GO:0002317)
0.1 0.5 GO:1903383 neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036482) positive regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902958) regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903383) negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903384)
0.1 0.3 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1 0.6 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.1 0.4 GO:0002879 positive regulation of acute inflammatory response to non-antigenic stimulus(GO:0002879)
0.1 0.5 GO:0060585 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.1 1.1 GO:0006477 protein sulfation(GO:0006477)
0.1 1.6 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.1 0.8 GO:0015722 canalicular bile acid transport(GO:0015722)
0.1 0.5 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.1 0.8 GO:0002432 granuloma formation(GO:0002432)
0.1 0.4 GO:1904139 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.1 0.5 GO:1903609 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
0.1 0.5 GO:0046882 negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.1 3.7 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.1 0.9 GO:0086023 adrenergic receptor signaling pathway involved in heart process(GO:0086023)
0.1 1.2 GO:0070995 NADPH oxidation(GO:0070995)
0.1 0.8 GO:0042427 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.1 1.0 GO:0034242 negative regulation of syncytium formation by plasma membrane fusion(GO:0034242)
0.1 0.2 GO:0071918 urea transmembrane transport(GO:0071918)
0.1 0.2 GO:0048880 visceral motor neuron differentiation(GO:0021524) sensory system development(GO:0048880) peripheral nervous system neuron axonogenesis(GO:0048936)
0.1 0.5 GO:0061113 pancreas morphogenesis(GO:0061113)
0.1 2.3 GO:1902175 regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902175)
0.1 0.4 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.1 0.2 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
0.1 0.5 GO:0030916 otic vesicle formation(GO:0030916)
0.1 7.0 GO:0007586 digestion(GO:0007586)
0.1 0.3 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.1 1.2 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.1 0.7 GO:0051026 chiasma assembly(GO:0051026)
0.1 0.6 GO:0090527 actin filament reorganization(GO:0090527)
0.1 0.2 GO:0061193 taste bud development(GO:0061193)
0.1 0.2 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137) mesenchymal stem cell proliferation(GO:0097168)
0.1 0.1 GO:0060529 female genitalia morphogenesis(GO:0048807) cloacal septation(GO:0060197) squamous basal epithelial stem cell differentiation involved in prostate gland acinus development(GO:0060529)
0.1 0.3 GO:0031133 regulation of axon diameter(GO:0031133)
0.1 0.1 GO:0009957 epidermal cell fate specification(GO:0009957)
0.1 0.4 GO:1903298 regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903297) negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903298)
0.0 0.1 GO:2000229 pancreatic stellate cell proliferation(GO:0072343) regulation of pancreatic stellate cell proliferation(GO:2000229)
0.0 0.2 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.0 0.1 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.0 0.2 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0 0.2 GO:0090472 dibasic protein processing(GO:0090472)
0.0 0.5 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.0 0.2 GO:0014719 skeletal muscle satellite cell activation(GO:0014719)
0.0 0.1 GO:0002182 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.0 0.3 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.3 GO:0032308 positive regulation of prostaglandin secretion(GO:0032308)
0.0 0.1 GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.0 0.7 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.2 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.0 0.4 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.2 GO:0010593 negative regulation of lamellipodium assembly(GO:0010593)
0.0 0.3 GO:2000860 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.0 0.2 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.0 0.3 GO:0002553 histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
0.0 0.5 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 0.1 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.0 0.2 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.5 GO:0046697 decidualization(GO:0046697)
0.0 0.4 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.2 GO:0050957 equilibrioception(GO:0050957)
0.0 0.1 GO:0060605 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0 0.1 GO:0042450 arginine biosynthetic process via ornithine(GO:0042450)
0.0 0.1 GO:0038044 transforming growth factor-beta secretion(GO:0038044)
0.0 0.6 GO:0031069 hair follicle morphogenesis(GO:0031069)
0.0 0.2 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.0 0.4 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.5 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0 0.1 GO:0006172 ADP biosynthetic process(GO:0006172)
0.0 0.3 GO:0010225 response to UV-C(GO:0010225)
0.0 0.1 GO:0002430 complement receptor mediated signaling pathway(GO:0002430) tolerance induction dependent upon immune response(GO:0002461)
0.0 3.1 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.0 0.0 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.0 1.5 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.0 0.1 GO:0002826 negative regulation of T-helper 1 type immune response(GO:0002826)
0.0 0.6 GO:0051642 centrosome localization(GO:0051642)
0.0 1.9 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.0 GO:0014900 regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900)
0.0 0.2 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.0 0.1 GO:0070495 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.3 0.8 GO:0046691 intracellular canaliculus(GO:0046691)
0.2 0.5 GO:0043512 inhibin-betaglycan-ActRII complex(GO:0034673) inhibin A complex(GO:0043512)
0.1 1.4 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 0.5 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 1.8 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 1.2 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.6 GO:0045179 apical cortex(GO:0045179)
0.0 3.7 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.5 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.1 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.0 0.4 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.2 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.3 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.1 GO:0001520 outer dense fiber(GO:0001520)
0.0 23.9 GO:0005615 extracellular space(GO:0005615)
0.0 1.3 GO:0030667 secretory granule membrane(GO:0030667)
0.0 0.7 GO:0000795 synaptonemal complex(GO:0000795)
0.0 0.3 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.2 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.9 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.3 1.2 GO:0004921 interleukin-11 receptor activity(GO:0004921) interleukin-11 binding(GO:0019970)
0.3 2.5 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.2 1.1 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.2 3.7 GO:0004806 triglyceride lipase activity(GO:0004806)
0.2 0.8 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.2 5.2 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.2 1.2 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.2 3.8 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.1 GO:0070051 fibrinogen binding(GO:0070051)
0.1 0.9 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.1 0.6 GO:0055056 dehydroascorbic acid transporter activity(GO:0033300) D-glucose transmembrane transporter activity(GO:0055056)
0.1 0.5 GO:0031708 endothelin B receptor binding(GO:0031708)
0.1 3.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 1.3 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 0.5 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.1 1.1 GO:0070700 BMP receptor binding(GO:0070700)
0.1 0.6 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.1 2.1 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 0.5 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.1 0.7 GO:0030983 mismatched DNA binding(GO:0030983)
0.1 0.2 GO:0042015 interleukin-20 binding(GO:0042015)
0.1 1.0 GO:0005372 water transmembrane transporter activity(GO:0005372)
0.1 0.7 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.1 10.2 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 1.9 GO:0001968 fibronectin binding(GO:0001968)
0.1 0.5 GO:0034711 inhibin binding(GO:0034711)
0.1 0.5 GO:0008556 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.0 1.1 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.0 0.1 GO:0002113 interleukin-33 binding(GO:0002113)
0.0 0.2 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.1 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0 0.1 GO:0008158 smoothened binding(GO:0005119) hedgehog receptor activity(GO:0008158)
0.0 0.7 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.8 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.2 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 3.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.5 GO:0070330 aromatase activity(GO:0070330)
0.0 0.2 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.0 0.2 GO:0001849 complement component C1q binding(GO:0001849)
0.0 1.2 GO:0050699 WW domain binding(GO:0050699)
0.0 0.4 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 1.0 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.1 GO:0016743 carboxyl- or carbamoyltransferase activity(GO:0016743)
0.0 0.3 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.2 GO:0051022 Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0 0.6 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.1 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.0 0.3 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.0 GO:0004517 nitric-oxide synthase activity(GO:0004517) tetrahydrobiopterin binding(GO:0034617)
0.0 0.2 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.5 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 4.0 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 0.1 GO:0004875 complement receptor activity(GO:0004875)
0.0 1.0 GO:0003823 antigen binding(GO:0003823)
0.0 0.3 GO:0097602 cullin family protein binding(GO:0097602)
0.0 1.3 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 9.9 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.3 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.4 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 2.7 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 2.4 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.3 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 2.6 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 1.1 PID BMP PATHWAY BMP receptor signaling
0.0 0.9 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.7 PID ALK1 PATHWAY ALK1 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.5 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.2 5.2 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.2 2.9 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.1 0.9 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 1.7 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 0.8 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 0.9 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 1.3 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.8 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 1.2 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.7 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 0.2 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.5 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.3 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 0.3 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.4 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.7 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions