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12D miR HR13_24

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Results for Tbx5

Z-value: 1.56

Motif logo

Transcription factors associated with Tbx5

Gene Symbol Gene ID Gene Info
ENSMUSG00000018263.8 T-box 5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Tbx5mm10_v2_chr5_+_119834663_119834663-0.721.2e-02Click!

Activity profile of Tbx5 motif

Sorted Z-values of Tbx5 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_+_79810727 6.07 ENSMUST00000107394.1
mesoderm posterior 2
chr11_+_120530688 4.07 ENSMUST00000026119.7
glucagon receptor
chr2_-_144331695 3.15 ENSMUST00000103171.3
ovo-like 2 (Drosophila)
chr2_-_144332146 3.14 ENSMUST00000037423.3
ovo-like 2 (Drosophila)
chr7_-_79793788 3.07 ENSMUST00000032760.5
mesoderm posterior 1
chr19_+_54045182 2.94 ENSMUST00000036700.5
adrenergic receptor, alpha 2a
chr7_-_100658394 2.60 ENSMUST00000138830.1
ENSMUST00000107044.3
ENSMUST00000116287.2
pleckstrin homology domain containing, family B (evectins) member 1
chr2_+_70562147 2.37 ENSMUST00000148210.1
glutamate decarboxylase 1
chr4_+_58943575 2.31 ENSMUST00000107554.1
zinc finger with KRAB and SCAN domains 16
chr9_-_95845215 2.31 ENSMUST00000093800.2
plastin 1 (I-isoform)
chr8_-_85119637 2.29 ENSMUST00000098550.3
zinc finger protein 791
chr8_+_76902277 2.17 ENSMUST00000109912.1
ENSMUST00000128862.1
ENSMUST00000109911.1
nuclear receptor subfamily 3, group C, member 2
chr7_-_100658364 2.06 ENSMUST00000107043.1
pleckstrin homology domain containing, family B (evectins) member 1
chr9_-_44320229 1.99 ENSMUST00000065080.8
C2 calcium-dependent domain containing 2-like
chr7_-_141117772 1.81 ENSMUST00000067836.7
anoctamin 9
chr11_+_96929260 1.77 ENSMUST00000054311.5
ENSMUST00000107636.3
proline rich 15-like
chr11_+_69965396 1.77 ENSMUST00000018713.6
claudin 7
chr9_-_62537036 1.71 ENSMUST00000048043.5
coronin, actin binding protein, 2B
chr11_+_96929367 1.69 ENSMUST00000062172.5
proline rich 15-like
chr8_-_105933832 1.65 ENSMUST00000034368.6
chymotrypsin-like
chr2_+_4919004 1.60 ENSMUST00000027975.7
phytanoyl-CoA hydroxylase
chr7_-_4546567 1.58 ENSMUST00000065957.5
synaptotagmin V
chr5_-_139819906 1.53 ENSMUST00000147328.1
transmembrane protein 184a
chr9_+_107581296 1.50 ENSMUST00000040059.2
hyaluronoglucosaminidase 3
chr4_-_134018829 1.37 ENSMUST00000051674.2
lin-28 homolog A (C. elegans)
chr3_+_126596993 1.35 ENSMUST00000163226.1
ENSMUST00000066466.6
ENSMUST00000169051.1
calcium/calmodulin-dependent protein kinase II, delta
chr12_-_113422730 1.34 ENSMUST00000177715.1
ENSMUST00000103426.1
immunoglobulin heavy constant mu
chr3_-_90465858 1.33 ENSMUST00000029540.6
natriuretic peptide receptor 1
chr3_+_126596951 1.32 ENSMUST00000106402.1
calcium/calmodulin-dependent protein kinase II, delta
chr5_-_116591811 1.26 ENSMUST00000076124.5
serine/arginine repetitive matrix 4
chr7_-_19023538 1.24 ENSMUST00000036018.5
forkhead box A3
chrX_+_169036610 1.23 ENSMUST00000087016.4
ENSMUST00000112129.1
ENSMUST00000112131.2
Rho GTPase activating protein 6
chr19_+_6341121 1.21 ENSMUST00000025897.6
ENSMUST00000130382.1
mitogen-activated protein kinase kinase kinase kinase 2
chr1_-_3671498 1.21 ENSMUST00000070533.4
X Kell blood group precursor related family member 4
chr16_+_93683184 1.20 ENSMUST00000039620.6
carbonyl reductase 3
chr9_+_107580746 1.20 ENSMUST00000148440.1
hyaluronoglucosaminidase 3
chrX_+_159840463 1.19 ENSMUST00000112451.1
ENSMUST00000112453.2
SH3-domain kinase binding protein 1
chr17_+_21383725 1.18 ENSMUST00000056107.4
ENSMUST00000162659.1
zinc finger protein 677
chr11_+_72961163 1.18 ENSMUST00000108486.1
ENSMUST00000108484.1
ENSMUST00000021142.7
ENSMUST00000108485.2
ENSMUST00000163326.1
ATPase, Ca++ transporting, ubiquitous
chr9_-_43239816 1.16 ENSMUST00000034512.5
OAF homolog (Drosophila)
chr6_+_30639218 1.14 ENSMUST00000031806.9
carboxypeptidase A1, pancreatic
chr6_-_52012476 1.13 ENSMUST00000078214.5
src family associated phosphoprotein 2
chr15_+_98634743 1.09 ENSMUST00000003442.7
calcium channel, voltage-dependent, beta 3 subunit
chr16_+_17276337 1.08 ENSMUST00000159065.1
ENSMUST00000159494.1
ENSMUST00000159811.1
transmembrane protein 191C
chr8_-_47675556 1.08 ENSMUST00000125536.1
inhibitor of growth family, member 2
chr17_+_32506446 1.07 ENSMUST00000165999.1
cytochrome P450, family 4, subfamily f, polypeptide 17
chr3_+_126597299 1.05 ENSMUST00000106400.2
ENSMUST00000106401.1
calcium/calmodulin-dependent protein kinase II, delta
chr16_+_17276291 1.05 ENSMUST00000164950.1
ENSMUST00000159242.1
transmembrane protein 191C
chrX_+_134295225 1.01 ENSMUST00000037687.7
transmembrane protein 35
chr1_+_188953744 1.01 ENSMUST00000127077.1
Usher syndrome 2A (autosomal recessive, mild)
chr17_+_24488773 1.01 ENSMUST00000024958.7
CASK interacting protein 1
chr3_+_132085281 1.00 ENSMUST00000029665.5
dickkopf homolog 2 (Xenopus laevis)
chr10_-_86705485 1.00 ENSMUST00000020238.7
heat shock protein 90, beta (Grp94), member 1
chr11_-_95076657 1.00 ENSMUST00000001548.7
integrin alpha 3
chr7_+_113513829 0.99 ENSMUST00000033018.8
fatty acyl CoA reductase 1
chr15_-_78468620 0.97 ENSMUST00000017086.3
transmembrane serine protease 6
chr4_-_140665891 0.96 ENSMUST00000069623.5
Rho guanine nucleotide exchange factor (GEF) 10-like
chr17_+_5975740 0.94 ENSMUST00000115790.1
synaptojanin 2
chr4_-_43045686 0.94 ENSMUST00000107956.1
ENSMUST00000107957.1
family with sequence similarity 214, member B
chr11_+_53519725 0.93 ENSMUST00000108987.1
ENSMUST00000121334.1
ENSMUST00000117061.1
septin 8
chr7_-_45238794 0.92 ENSMUST00000098461.1
ENSMUST00000107797.1
CD37 antigen
chrX_-_51205773 0.90 ENSMUST00000114875.1
muscleblind-like 3 (Drosophila)
chr11_-_95076797 0.90 ENSMUST00000145671.1
ENSMUST00000120375.1
integrin alpha 3
chr2_-_32387760 0.89 ENSMUST00000050785.8
lipocalin 2
chr1_+_74601548 0.88 ENSMUST00000087186.4
serine/threonine kinase 36
chr14_-_72709534 0.88 ENSMUST00000162478.1
fibronectin type III domain containing 3A
chr15_-_9748777 0.85 ENSMUST00000159368.1
ENSMUST00000159093.1
ENSMUST00000162780.1
ENSMUST00000160236.1
ENSMUST00000041840.7
sperm flagellar 2
chr19_+_22448242 0.85 ENSMUST00000037901.6
transient receptor potential cation channel, subfamily M, member 3
chr11_+_70700606 0.85 ENSMUST00000137119.2
kinesin family member 1C
chr7_-_19749464 0.84 ENSMUST00000075447.7
ENSMUST00000108450.3
poliovirus receptor-related 2
chr12_-_21417356 0.84 ENSMUST00000103002.1
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide
chr3_+_127789872 0.82 ENSMUST00000054483.7
ENSMUST00000163775.1
TRAF-interacting protein with forkhead-associated domain
chr7_+_113513854 0.82 ENSMUST00000067929.8
ENSMUST00000129087.1
ENSMUST00000164745.1
ENSMUST00000136158.1
fatty acyl CoA reductase 1
chr9_+_108953578 0.81 ENSMUST00000112070.1
collagen, type VII, alpha 1
chr9_-_110476637 0.80 ENSMUST00000111934.1
ENSMUST00000068025.6
kelch-like 18
chr1_-_157108632 0.79 ENSMUST00000118207.1
ENSMUST00000027884.6
ENSMUST00000121911.1
testis expressed 35
chr13_+_13590402 0.79 ENSMUST00000110559.1
lysosomal trafficking regulator
chr10_+_93641041 0.78 ENSMUST00000020204.4
netrin 4
chr18_-_38209762 0.78 ENSMUST00000057185.6
protocadherin 1
chr17_-_6948283 0.77 ENSMUST00000024572.9
radial spoke 3B homolog (Chlamydomonas)
chr6_-_52208694 0.77 ENSMUST00000062829.7
homeobox A6
chr9_+_108953597 0.77 ENSMUST00000026740.5
collagen, type VII, alpha 1
chr11_-_70220776 0.76 ENSMUST00000141290.1
solute carrier family 16 (monocarboxylic acid transporters), member 13
chr6_+_108828633 0.76 ENSMUST00000089162.3
ER degradation enhancer, mannosidase alpha-like 1
chr11_+_70700473 0.75 ENSMUST00000152618.2
ENSMUST00000102554.1
ENSMUST00000094499.4
ENSMUST00000072187.5
kinesin family member 1C
chr10_+_86705811 0.74 ENSMUST00000061458.7
ENSMUST00000075632.6
cDNA sequence BC030307
chr7_-_126898249 0.74 ENSMUST00000121532.1
ENSMUST00000032926.5
transmembrane protein 219
chr7_-_45239108 0.73 ENSMUST00000033063.6
CD37 antigen
chr19_-_6925367 0.72 ENSMUST00000057716.4
testis expressed 40
chr17_+_46681038 0.72 ENSMUST00000002845.6
male enhanced antigen 1
chr1_+_109982710 0.72 ENSMUST00000112701.1
cadherin 7, type 2
chr11_+_69095217 0.72 ENSMUST00000101004.2
period circadian clock 1
chr1_-_156718894 0.72 ENSMUST00000086153.6
family with sequence similarity 20, member B
chr5_-_24329556 0.71 ENSMUST00000115098.2
potassium voltage-gated channel, subfamily H (eag-related), member 2
chr6_+_124663027 0.71 ENSMUST00000004381.7
lysophosphatidylcholine acyltransferase 3
chr15_-_89425795 0.71 ENSMUST00000168376.1
carnitine palmitoyltransferase 1b, muscle
chrX_+_41401304 0.70 ENSMUST00000076349.5
glutamate receptor, ionotropic, AMPA3 (alpha 3)
chr14_+_80000292 0.70 ENSMUST00000088735.3
olfactomedin 4
chr3_-_20275659 0.69 ENSMUST00000011607.5
carboxypeptidase B1 (tissue)
chr11_+_116280939 0.68 ENSMUST00000055872.2
galanin receptor 2
chr1_+_88134786 0.68 ENSMUST00000113134.1
ENSMUST00000140092.1
UDP glucuronosyltransferase 1 family, polypeptide A6A
chr1_+_74601441 0.68 ENSMUST00000087183.4
ENSMUST00000148456.1
ENSMUST00000113694.1
serine/threonine kinase 36
chr4_+_128883549 0.68 ENSMUST00000035667.8
tripartite motif-containing 62
chr9_+_107400043 0.67 ENSMUST00000166799.1
ENSMUST00000170737.1
calcium channel, voltage-dependent, alpha 2/delta subunit 2
chr11_+_110399115 0.67 ENSMUST00000020949.5
ENSMUST00000100260.1
mitogen-activated protein kinase kinase 6
chr3_+_51483966 0.66 ENSMUST00000054387.6
RAB33B, member of RAS oncogene family
chrX_-_51205990 0.66 ENSMUST00000114876.2
muscleblind-like 3 (Drosophila)
chr4_+_9844349 0.64 ENSMUST00000057613.2
growth differentiation factor 6
chr11_-_70220794 0.64 ENSMUST00000159867.1
solute carrier family 16 (monocarboxylic acid transporters), member 13
chrX_+_20364481 0.64 ENSMUST00000033372.6
ENSMUST00000115391.1
ENSMUST00000115387.1
retinitis pigmentosa 2 homolog (human)
chr6_-_52191695 0.64 ENSMUST00000101395.2
homeobox A4
chr2_-_33371400 0.64 ENSMUST00000113164.1
ENSMUST00000091039.2
ENSMUST00000042615.6
Ral GEF with PH domain and SH3 binding motif 1
chr1_+_86045863 0.63 ENSMUST00000165824.1
RIKEN cDNA 2810459M11 gene
chr4_-_151108244 0.62 ENSMUST00000131948.1
calmodulin binding transcription activator 1
chr8_+_13037308 0.62 ENSMUST00000063820.5
ENSMUST00000033821.4
coagulation factor X
chr14_-_66009204 0.61 ENSMUST00000059970.7
gulonolactone (L-) oxidase
chr15_+_79028212 0.61 ENSMUST00000180086.1
H1 histone family, member 0
chr7_-_27396542 0.60 ENSMUST00000108363.1
spectrin beta, non-erythrocytic 4
chr11_+_66911981 0.60 ENSMUST00000123434.2
phosphoinositide-interacting regulator of transient receptor potential channels
chr6_-_113343975 0.60 ENSMUST00000155543.1
ENSMUST00000032409.8
calcium/calmodulin-dependent protein kinase I
chr2_+_11642786 0.59 ENSMUST00000028111.4
interleukin 2 receptor, alpha chain
chrX_+_129749740 0.59 ENSMUST00000167619.2
ENSMUST00000037854.8
diaphanous homolog 2 (Drosophila)
chr3_+_90062781 0.59 ENSMUST00000029551.2
RIKEN cDNA 1700094D03 gene
chr2_-_131187282 0.58 ENSMUST00000028801.1
sperm flagellar 1
chr11_-_99993992 0.58 ENSMUST00000105049.1
keratin associated protein 17-1
chr3_-_94786430 0.58 ENSMUST00000107272.1
cingulin
chr1_+_23761926 0.57 ENSMUST00000063663.5
beta-1,3-glucuronyltransferase 2 (glucuronosyltransferase S)
chr8_+_125669818 0.57 ENSMUST00000053078.3
microtubule-associated protein 10
chr9_+_75232013 0.56 ENSMUST00000036555.6
myosin VC
chr12_-_35534973 0.56 ENSMUST00000116436.2
aryl-hydrocarbon receptor
chr1_+_132417409 0.56 ENSMUST00000045110.7
dual serine/threonine and tyrosine protein kinase
chr1_-_156718989 0.56 ENSMUST00000122424.1
family with sequence similarity 20, member B
chr6_+_48395586 0.56 ENSMUST00000114571.1
ENSMUST00000114572.3
ENSMUST00000031815.5
KRAB-A domain containing 1
chr4_+_84884418 0.55 ENSMUST00000169371.2
centlein, centrosomal protein
chr2_-_121806988 0.55 ENSMUST00000110592.1
FERM domain containing 5
chr10_-_128821576 0.55 ENSMUST00000026409.3
ORM1-like 2 (S. cerevisiae)
chrX_+_129749830 0.55 ENSMUST00000113320.2
diaphanous homolog 2 (Drosophila)
chr7_+_31059342 0.55 ENSMUST00000039775.7
leucine-rich repeat LGI family, member 4
chr13_-_62888282 0.54 ENSMUST00000092888.4
fructose bisphosphatase 1
chr11_+_60479915 0.54 ENSMUST00000126522.1
myosin XV
chr15_-_75888754 0.54 ENSMUST00000184858.1
maestro heat-like repeat family member 6
chr3_-_94786469 0.54 ENSMUST00000107273.1
cingulin
chr13_-_38036923 0.54 ENSMUST00000110233.1
ENSMUST00000074969.4
ENSMUST00000131066.1
cancer antigen 1
chr1_-_87089928 0.53 ENSMUST00000027455.6
alkaline phosphatase, placental-like 2
chr4_+_33078796 0.53 ENSMUST00000131920.1
gamma-aminobutyric acid (GABA) C receptor, subunit rho 2
chr1_+_72284367 0.53 ENSMUST00000027380.5
ENSMUST00000141783.1
transmembrane protein 169
chr19_+_46341118 0.53 ENSMUST00000128041.1
transmembrane protein 180
chrX_+_41401128 0.52 ENSMUST00000115103.2
glutamate receptor, ionotropic, AMPA3 (alpha 3)
chr17_+_5975586 0.52 ENSMUST00000142409.1
ENSMUST00000061091.7
synaptojanin 2
chr17_-_31144271 0.52 ENSMUST00000024826.7
trefoil factor 2 (spasmolytic protein 1)
chr14_+_59440947 0.51 ENSMUST00000022553.5
calcium binding protein 39-like
chr13_-_99900645 0.51 ENSMUST00000022150.6
CART prepropeptide
chr10_+_75566257 0.51 ENSMUST00000129232.1
ENSMUST00000143792.1
gamma-glutamyltransferase 1
chr1_-_75232093 0.51 ENSMUST00000180101.1
RIKEN cDNA A630095N17 gene
chr13_-_56296551 0.51 ENSMUST00000021970.9
chemokine (C-X-C motif) ligand 14
chr9_+_118926453 0.50 ENSMUST00000073109.5
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
chr17_-_42611313 0.50 ENSMUST00000068355.6
opsin 5
chr19_-_41385070 0.50 ENSMUST00000059672.7
phosphoinositide-3-kinase adaptor protein 1
chr2_+_24186469 0.50 ENSMUST00000057567.2
interleukin 1 family, member 9
chrX_-_73458990 0.49 ENSMUST00000033737.8
ENSMUST00000077243.4
HAUS augmin-like complex, subunit 7
chr18_+_61555308 0.49 ENSMUST00000165721.1
ENSMUST00000115246.2
ENSMUST00000166990.1
ENSMUST00000163205.1
ENSMUST00000170862.1
casein kinase 1, alpha 1
chr19_-_6235804 0.49 ENSMUST00000025695.9
protein phosphatase 2, regulatory subunit B (B56), beta isoform
chr8_-_67910911 0.48 ENSMUST00000093468.5
pleckstrin and Sec7 domain containing 3
chr9_+_107547288 0.48 ENSMUST00000010188.7
zinc finger, MYND domain containing 10
chr15_-_101869695 0.48 ENSMUST00000087996.5
keratin 77
chrX_-_49886401 0.47 ENSMUST00000070304.2
olfactory receptor 1322
chr11_+_45980309 0.47 ENSMUST00000049038.3
SRY-box containing gene 30
chr7_+_140845562 0.47 ENSMUST00000035300.5
secretoglobin, family 1C, member 1
chr18_+_61555258 0.46 ENSMUST00000165123.1
casein kinase 1, alpha 1
chr4_-_71757965 0.46 ENSMUST00000084489.2
predicted gene 11232
chr4_-_19708922 0.45 ENSMUST00000108246.2
WW domain containing E3 ubiquitin protein ligase 1
chr11_-_72795801 0.45 ENSMUST00000079681.5
cytochrome b5 domain containing 2
chr2_-_38926217 0.45 ENSMUST00000076275.4
ENSMUST00000142130.1
nuclear receptor subfamily 6, group A, member 1
chr7_-_142666816 0.45 ENSMUST00000105935.1
insulin-like growth factor 2
chr17_+_72836678 0.45 ENSMUST00000045174.5
yippee-like 5 (Drosophila)
chr1_-_74601345 0.44 ENSMUST00000136078.1
ENSMUST00000132081.1
ENSMUST00000113721.1
ENSMUST00000027357.5
ring finger protein 25
chrX_-_59134421 0.44 ENSMUST00000033473.5
fibroblast growth factor 13
chr5_-_5514730 0.44 ENSMUST00000115445.1
ENSMUST00000179804.1
ENSMUST00000125110.1
ENSMUST00000115446.1
claudin 12
chr12_-_84773087 0.43 ENSMUST00000021668.8
Niemann Pick type C2
chr1_+_9798123 0.43 ENSMUST00000168907.1
ENSMUST00000166384.1
serum/glucocorticoid regulated kinase 3
chr6_+_48395652 0.43 ENSMUST00000077093.4
KRAB-A domain containing 1
chr7_+_141461728 0.43 ENSMUST00000167491.1
ENSMUST00000165194.1
EF-hand calcium binding domain 4A
chr5_+_17574726 0.43 ENSMUST00000169603.1
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr7_+_44748584 0.42 ENSMUST00000171821.1
vaccinia related kinase 3
chr4_+_5644084 0.42 ENSMUST00000054857.6
family with sequence similarity 110, member B
chr8_+_88697022 0.42 ENSMUST00000043526.8
cylindromatosis (turban tumor syndrome)
chr18_+_61555689 0.42 ENSMUST00000167187.1
casein kinase 1, alpha 1
chr9_+_88839164 0.42 ENSMUST00000163255.2
tripartite motif-containing 43C
chr4_+_132564051 0.42 ENSMUST00000070690.7
platelet-activating factor receptor
chr18_+_35829798 0.41 ENSMUST00000060722.6
CXXC finger 5
chr6_-_136661928 0.41 ENSMUST00000032336.4
phospholipase B domain containing 1
chr15_-_103255433 0.40 ENSMUST00000075192.6
nuclear factor, erythroid derived 2
chr3_+_92352141 0.40 ENSMUST00000068399.1
small proline-rich protein 2E
chr10_-_127751707 0.40 ENSMUST00000079692.5
G protein-coupled receptor 182
chr6_+_54681687 0.39 ENSMUST00000046276.6
RIKEN cDNA 2410066E13 gene
chr6_+_125049903 0.39 ENSMUST00000112413.1
proacrosin binding protein
chr19_-_10604258 0.39 ENSMUST00000037678.6
dihydroxyacetone kinase 2 homolog (yeast)
chr7_+_89980749 0.39 ENSMUST00000181784.1
predicted gene, 26529
chr2_+_70661556 0.39 ENSMUST00000112201.1
ENSMUST00000028509.4
ENSMUST00000133432.1
ENSMUST00000112205.1
golgi reassembly stacking protein 2
chr19_-_4439388 0.39 ENSMUST00000117462.1
ENSMUST00000048197.3
ras homolog gene family, member D

Network of associatons between targets according to the STRING database.

First level regulatory network of Tbx5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 9.1 GO:0008078 mesodermal cell migration(GO:0008078)
0.8 6.3 GO:0060214 endocardium formation(GO:0060214)
0.7 2.2 GO:0031959 mineralocorticoid receptor signaling pathway(GO:0031959)
0.7 4.1 GO:0033762 response to glucagon(GO:0033762)
0.6 3.7 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
0.6 1.8 GO:2001226 negative regulation of chloride transport(GO:2001226)
0.6 2.3 GO:1902896 terminal web assembly(GO:1902896)
0.5 1.6 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.5 1.6 GO:0007228 positive regulation of hh target transcription factor activity(GO:0007228)
0.5 2.9 GO:0035625 receptor transactivation(GO:0035624) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625)
0.4 1.3 GO:0002343 peripheral B cell selection(GO:0002343) B cell affinity maturation(GO:0002344)
0.4 1.2 GO:0070368 positive regulation of hepatocyte differentiation(GO:0070368)
0.4 1.2 GO:0042376 phylloquinone metabolic process(GO:0042374) phylloquinone catabolic process(GO:0042376) quinone catabolic process(GO:1901662)
0.3 2.4 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.3 2.7 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.3 1.8 GO:0010166 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.3 1.5 GO:0018992 germ-line sex determination(GO:0018992)
0.3 0.8 GO:1904154 positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.2 1.9 GO:0030886 negative regulation of myeloid dendritic cell activation(GO:0030886)
0.2 1.0 GO:0048496 maintenance of organ identity(GO:0048496)
0.2 0.6 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.2 0.8 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.2 0.7 GO:0045054 constitutive secretory pathway(GO:0045054)
0.2 0.7 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.2 0.6 GO:1900060 negative regulation of ceramide biosynthetic process(GO:1900060)
0.2 0.5 GO:0046351 disaccharide biosynthetic process(GO:0046351)
0.2 1.1 GO:0042078 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.2 0.7 GO:1902303 negative regulation of potassium ion export(GO:1902303)
0.2 1.9 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.2 0.5 GO:0070093 negative regulation of glucagon secretion(GO:0070093)
0.2 1.7 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.2 0.8 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.2 0.6 GO:0019853 L-ascorbic acid biosynthetic process(GO:0019853)
0.2 1.4 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.1 0.9 GO:1901678 iron coordination entity transport(GO:1901678)
0.1 0.7 GO:0097167 circadian regulation of translation(GO:0097167)
0.1 0.6 GO:0040010 positive regulation of growth rate(GO:0040010)
0.1 0.7 GO:1902608 regulation of large conductance calcium-activated potassium channel activity(GO:1902606) positive regulation of large conductance calcium-activated potassium channel activity(GO:1902608)
0.1 0.6 GO:0032485 regulation of Ral protein signal transduction(GO:0032485)
0.1 0.4 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.1 0.5 GO:1901740 negative regulation of myoblast fusion(GO:1901740)
0.1 0.4 GO:0042364 water-soluble vitamin biosynthetic process(GO:0042364)
0.1 1.1 GO:0061577 calcium ion transmembrane transport via high voltage-gated calcium channel(GO:0061577)
0.1 0.4 GO:1902941 regulation of voltage-gated chloride channel activity(GO:1902941) positive regulation of voltage-gated chloride channel activity(GO:1902943) positive regulation of gastro-intestinal system smooth muscle contraction(GO:1904306)
0.1 0.5 GO:0060455 negative regulation of gastric acid secretion(GO:0060455)
0.1 0.4 GO:0034242 negative regulation of syncytium formation by plasma membrane fusion(GO:0034242)
0.1 0.3 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
0.1 0.3 GO:0070543 response to linoleic acid(GO:0070543)
0.1 0.3 GO:2000969 positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.1 0.3 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.1 0.3 GO:0071544 diphosphoinositol polyphosphate catabolic process(GO:0071544)
0.1 1.8 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.1 0.2 GO:0046439 cysteine catabolic process(GO:0009093) L-cysteine catabolic process(GO:0019448) L-cysteine metabolic process(GO:0046439)
0.1 0.6 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.1 1.3 GO:1904424 regulation of GTP binding(GO:1904424)
0.1 0.7 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.1 0.4 GO:0097343 ripoptosome assembly(GO:0097343) ripoptosome assembly involved in necroptotic process(GO:1901026)
0.1 0.3 GO:0003218 cardiac left ventricle formation(GO:0003218)
0.1 0.5 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.1 0.2 GO:2001205 negative regulation of osteoclast development(GO:2001205)
0.1 0.6 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.1 1.1 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.1 1.0 GO:0097264 self proteolysis(GO:0097264)
0.1 0.2 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.1 0.4 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.1 0.4 GO:0003350 pulmonary myocardium development(GO:0003350) dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1 0.3 GO:0035565 regulation of pronephros size(GO:0035565) mesonephros morphogenesis(GO:0061206) mesonephric nephron development(GO:0061215) mesonephric nephron morphogenesis(GO:0061228) mesenchymal stem cell maintenance involved in mesonephric nephron morphogenesis(GO:0061235) regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061295) negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061296) mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:1901146)
0.1 0.4 GO:0035262 gonad morphogenesis(GO:0035262)
0.1 0.6 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.1 1.5 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.1 0.5 GO:1904378 maintenance of unfolded protein(GO:0036506) tail-anchored membrane protein insertion into ER membrane(GO:0071816) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.1 0.3 GO:0061589 calcium activated phosphatidylserine scrambling(GO:0061589)
0.1 1.0 GO:0071318 cellular response to ATP(GO:0071318)
0.1 1.3 GO:0015732 prostaglandin transport(GO:0015732)
0.1 0.2 GO:0009726 detection of nodal flow(GO:0003127) detection of endogenous stimulus(GO:0009726)
0.1 0.4 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.1 0.5 GO:1901748 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.1 0.4 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.1 0.5 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.1 0.2 GO:0009957 epidermal cell fate specification(GO:0009957)
0.1 0.2 GO:0010046 response to mycotoxin(GO:0010046)
0.1 0.7 GO:0052697 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.1 0.8 GO:0007288 sperm axoneme assembly(GO:0007288)
0.1 1.0 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.1 1.6 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.1 0.2 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.0 1.2 GO:0051895 activation of phospholipase C activity(GO:0007202) negative regulation of focal adhesion assembly(GO:0051895)
0.0 0.1 GO:0090327 negative regulation of locomotion involved in locomotory behavior(GO:0090327)
0.0 0.5 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.2 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 2.0 GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0035774)
0.0 1.2 GO:0006903 vesicle targeting(GO:0006903)
0.0 0.2 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.0 1.9 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 1.0 GO:0006991 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 0.4 GO:0007343 egg activation(GO:0007343)
0.0 0.5 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.1 GO:2000224 regulation of testosterone biosynthetic process(GO:2000224)
0.0 0.2 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241) detection of muscle stretch(GO:0035995)
0.0 0.4 GO:0036309 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.0 0.2 GO:1903033 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.0 0.3 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.0 0.3 GO:0015871 choline transport(GO:0015871)
0.0 0.9 GO:0060009 Sertoli cell development(GO:0060009)
0.0 0.2 GO:0009235 cobalamin metabolic process(GO:0009235)
0.0 0.1 GO:0002786 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) regulation of antimicrobial peptide production(GO:0002784) regulation of antibacterial peptide production(GO:0002786) positive regulation of antibacterial peptide production(GO:0002803)
0.0 0.4 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.1 GO:0007403 glial cell fate determination(GO:0007403)
0.0 0.2 GO:0010747 positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747)
0.0 0.5 GO:0036159 inner dynein arm assembly(GO:0036159)
0.0 0.9 GO:0032332 positive regulation of chondrocyte differentiation(GO:0032332)
0.0 1.6 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.0 0.7 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.0 0.6 GO:0032252 secretory granule localization(GO:0032252)
0.0 1.2 GO:0001919 regulation of receptor recycling(GO:0001919)
0.0 0.1 GO:0043415 positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.0 0.2 GO:0045900 negative regulation of translational elongation(GO:0045900)
0.0 0.7 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.2 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0 0.5 GO:0006691 leukotriene metabolic process(GO:0006691)
0.0 0.2 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.0 0.4 GO:0032366 intracellular sterol transport(GO:0032366) intracellular cholesterol transport(GO:0032367)
0.0 0.4 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.3 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.0 0.3 GO:0019321 pentose metabolic process(GO:0019321)
0.0 0.3 GO:0021540 corpus callosum morphogenesis(GO:0021540) corticospinal tract morphogenesis(GO:0021957)
0.0 0.3 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.0 0.6 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.0 0.1 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.1 GO:0003349 epicardium-derived cardiac endothelial cell differentiation(GO:0003349)
0.0 0.7 GO:0022011 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0 0.2 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.0 GO:0032430 positive regulation of phospholipase A2 activity(GO:0032430)
0.0 1.0 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.2 GO:0042711 maternal behavior(GO:0042711)
0.0 1.3 GO:0003382 epithelial cell morphogenesis(GO:0003382)
0.0 0.6 GO:0048266 behavioral response to pain(GO:0048266)
0.0 0.9 GO:0015909 long-chain fatty acid transport(GO:0015909)
0.0 0.6 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.5 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 1.3 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 0.1 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.0 0.7 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.0 0.1 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951) positive regulation of inclusion body assembly(GO:0090261)
0.0 0.3 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.0 0.1 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 0.4 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.0 0.2 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.1 GO:1990034 calcium ion export from cell(GO:1990034)
0.0 0.7 GO:0097006 regulation of plasma lipoprotein particle levels(GO:0097006)
0.0 0.4 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.2 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0 0.2 GO:1904376 negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376)
0.0 0.4 GO:0090109 regulation of focal adhesion assembly(GO:0051893) regulation of cell-substrate junction assembly(GO:0090109)
0.0 0.2 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.0 0.3 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.6 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.0 0.5 GO:0060612 adipose tissue development(GO:0060612)
0.0 0.1 GO:0048664 neuron fate determination(GO:0048664)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.6 1.9 GO:0034667 integrin alpha3-beta1 complex(GO:0034667)
0.3 1.6 GO:1990769 proximal neuron projection(GO:1990769)
0.3 2.3 GO:1990357 terminal web(GO:1990357)
0.3 1.0 GO:1990696 USH2 complex(GO:1990696)
0.2 1.3 GO:0019815 B cell receptor complex(GO:0019815)
0.2 1.1 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.2 0.7 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.1 4.3 GO:0043194 axon initial segment(GO:0043194)
0.1 0.6 GO:0035339 SPOTS complex(GO:0035339)
0.1 1.1 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 0.6 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 1.5 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.1 0.7 GO:0005796 Golgi lumen(GO:0005796)
0.1 1.4 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.1 0.5 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.1 0.3 GO:1990590 ATF1-ATF4 transcription factor complex(GO:1990590)
0.1 0.2 GO:0048179 activin receptor complex(GO:0048179)
0.1 0.2 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.1 1.0 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 1.8 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 0.4 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.1 0.5 GO:0070652 HAUS complex(GO:0070652)
0.1 2.4 GO:0060077 inhibitory synapse(GO:0060077)
0.1 1.2 GO:0032279 asymmetric synapse(GO:0032279)
0.1 1.8 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.1 5.2 GO:0001750 photoreceptor outer segment(GO:0001750)
0.1 0.7 GO:0042581 specific granule(GO:0042581)
0.1 1.3 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.3 GO:1990584 cardiac Troponin complex(GO:1990584)
0.0 0.2 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0 0.9 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.4 GO:0042629 mast cell granule(GO:0042629)
0.0 0.3 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.4 GO:0097542 ciliary tip(GO:0097542)
0.0 0.4 GO:0031983 vesicle lumen(GO:0031983)
0.0 0.8 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.4 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.5 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.6 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.4 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.2 GO:0097513 myosin II filament(GO:0097513)
0.0 0.4 GO:0001533 cornified envelope(GO:0001533)
0.0 1.6 GO:0001772 immunological synapse(GO:0001772)
0.0 1.5 GO:0031901 early endosome membrane(GO:0031901)
0.0 1.0 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 1.5 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.2 GO:0070852 cell body fiber(GO:0070852)
0.0 0.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.2 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.1 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.5 GO:0032420 stereocilium(GO:0032420)
0.0 1.4 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.5 GO:0045095 keratin filament(GO:0045095)
0.0 0.1 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.2 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.5 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.4 GO:0031430 M band(GO:0031430)
0.0 0.4 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.3 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.1 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.2 GO:0034704 calcium channel complex(GO:0034704)
0.0 0.6 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 1.8 GO:0005604 basement membrane(GO:0005604)
0.0 0.8 GO:0016459 myosin complex(GO:0016459)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.1 GO:0004967 glucagon receptor activity(GO:0004967)
0.9 2.7 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
0.7 2.9 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.7 2.2 GO:0017082 mineralocorticoid receptor activity(GO:0017082)
0.4 1.2 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.4 3.7 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.4 1.8 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.3 2.4 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.3 1.3 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.2 2.0 GO:0043559 insulin binding(GO:0043559)
0.2 0.6 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.2 0.6 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.2 0.9 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.2 1.2 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.2 0.5 GO:0005502 11-cis retinal binding(GO:0005502)
0.1 0.7 GO:0004966 galanin receptor activity(GO:0004966)
0.1 0.7 GO:1902282 phosphorelay sensor kinase activity(GO:0000155) voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.1 0.7 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.1 0.2 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.1 1.5 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.1 1.0 GO:0046790 virion binding(GO:0046790)
0.1 0.6 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1 0.8 GO:0043237 laminin-1 binding(GO:0043237)
0.1 1.4 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.1 0.3 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.1 0.6 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.1 1.8 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.1 1.6 GO:0031418 L-ascorbic acid binding(GO:0031418)
0.1 1.2 GO:0060229 phospholipase activator activity(GO:0016004) lipase activator activity(GO:0060229)
0.1 0.3 GO:0004492 methylmalonyl-CoA decarboxylase activity(GO:0004492)
0.1 0.8 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 0.4 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.1 0.2 GO:0008158 smoothened binding(GO:0005119) hedgehog receptor activity(GO:0008158)
0.1 1.3 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 1.4 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 0.5 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.1 1.9 GO:0043236 laminin binding(GO:0043236)
0.1 0.4 GO:0034235 GPI anchor binding(GO:0034235)
0.1 0.2 GO:0038100 nodal binding(GO:0038100)
0.1 0.2 GO:0004974 leukotriene receptor activity(GO:0004974)
0.1 0.6 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.1 0.2 GO:0051373 FATZ binding(GO:0051373)
0.1 0.2 GO:0031750 D3 dopamine receptor binding(GO:0031750) D5 dopamine receptor binding(GO:0031752)
0.1 0.5 GO:0015198 oligopeptide transporter activity(GO:0015198)
0.1 1.8 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 1.2 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 0.3 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.1 0.3 GO:0035497 cAMP response element binding(GO:0035497)
0.1 0.4 GO:1990380 Lys63-specific deubiquitinase activity(GO:0061578) Lys48-specific deubiquitinase activity(GO:1990380)
0.1 0.7 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.1 0.5 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 0.3 GO:0030172 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.0 0.3 GO:0000298 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.0 0.4 GO:0039706 co-receptor binding(GO:0039706)
0.0 0.4 GO:0097642 calcitonin family receptor activity(GO:0097642)
0.0 0.2 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0 0.4 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.3 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.4 GO:0034711 inhibin binding(GO:0034711)
0.0 0.5 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.3 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.3 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.6 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.9 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.2 GO:0008453 alanine-glyoxylate transaminase activity(GO:0008453)
0.0 0.3 GO:0045545 syndecan binding(GO:0045545)
0.0 0.5 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.5 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.8 GO:0005549 odorant binding(GO:0005549)
0.0 0.1 GO:0031699 beta-3 adrenergic receptor binding(GO:0031699)
0.0 1.2 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.1 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.2 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 0.2 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 16.6 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.4 GO:0010181 FMN binding(GO:0010181)
0.0 0.4 GO:0050308 sugar-phosphatase activity(GO:0050308)
0.0 1.4 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.9 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.7 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.4 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.5 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.9 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.3 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.0 1.0 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.2 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.5 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.7 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 1.9 GO:1902936 phosphatidylinositol bisphosphate binding(GO:1902936)
0.0 0.3 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.4 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.2 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.6 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.3 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 3.9 GO:0051015 actin filament binding(GO:0051015)
0.0 0.6 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.4 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.6 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.4 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.2 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.1 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.0 0.4 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 1.4 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 3.0 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 0.4 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.1 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.0 0.7 GO:0017022 myosin binding(GO:0017022)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.5 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 1.2 PID TNF PATHWAY TNF receptor signaling pathway
0.1 1.9 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 2.4 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 2.0 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.7 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.9 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 2.7 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.7 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.6 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.2 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.8 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 1.5 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.3 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.5 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 1.2 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.6 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.9 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.4 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.2 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.7 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.2 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.6 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.2 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.1 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.2 5.0 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.1 1.3 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 3.4 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.1 2.4 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.1 4.0 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.1 0.7 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.1 0.8 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 0.5 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 2.8 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 1.1 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 1.1 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 0.5 REACTOME OPSINS Genes involved in Opsins
0.1 1.4 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.9 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.6 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 1.1 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 0.6 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.3 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.6 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 1.5 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 1.3 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 1.5 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.5 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 1.1 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 2.6 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.7 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.6 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.5 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.4 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 1.0 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.4 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.4 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.7 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.6 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.2 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.5 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.3 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.5 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.7 REACTOME REGULATION OF INSULIN SECRETION Genes involved in Regulation of Insulin Secretion
0.0 0.2 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.5 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.3 REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION Genes involved in Nuclear Events (kinase and transcription factor activation)
0.0 0.3 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions