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12D miR HR13_24

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Results for Cdc5l

Z-value: 0.52

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Transcription factors associated with Cdc5l

Gene Symbol Gene ID Gene Info
ENSMUSG00000023932.8 cell division cycle 5-like (S. pombe)

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Cdc5lmm10_v2_chr17_-_45433682_45433709-0.766.9e-03Click!

Activity profile of Cdc5l motif

Sorted Z-values of Cdc5l motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_101869012 1.20 ENSMUST00000123321.1
folate receptor 1 (adult)
chr7_-_101868667 1.08 ENSMUST00000150184.1
folate receptor 1 (adult)
chr13_-_18382041 1.06 ENSMUST00000139064.2
ENSMUST00000175703.2
POU domain, class 6, transcription factor 2
chr2_+_58755177 0.67 ENSMUST00000102755.3
uridine phosphorylase 2
chr5_+_20702129 0.60 ENSMUST00000101556.4
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr2_+_106695594 0.52 ENSMUST00000016530.7
metallophosphoesterase domain containing 2
chr5_+_66968416 0.50 ENSMUST00000038188.7
LIM and calponin homology domains 1
chr6_+_142298419 0.43 ENSMUST00000041993.2
islet amyloid polypeptide
chr5_+_66968559 0.41 ENSMUST00000127184.1
LIM and calponin homology domains 1
chr5_-_136883115 0.41 ENSMUST00000057497.6
ENSMUST00000111103.1
collagen, type XXVI, alpha 1
chr17_-_78684262 0.38 ENSMUST00000145480.1
striatin, calmodulin binding protein
chr14_+_73237891 0.36 ENSMUST00000044405.6
lysophosphatidic acid receptor 6
chr1_+_109993982 0.34 ENSMUST00000027542.6
cadherin 7, type 2
chr10_+_17723220 0.31 ENSMUST00000038107.7
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
chr17_+_47140942 0.30 ENSMUST00000077951.7
transcriptional regulating factor 1
chr8_+_109990430 0.29 ENSMUST00000001720.7
ENSMUST00000143741.1
tyrosine aminotransferase
chr10_+_52391606 0.26 ENSMUST00000067085.4
nephrocan
chr11_+_59306920 0.24 ENSMUST00000000128.3
ENSMUST00000108783.3
wingless-type MMTV integration site 9A
chr12_+_59129757 0.24 ENSMUST00000069430.8
ENSMUST00000177370.1
CTAGE family, member 5
chr6_+_88724828 0.24 ENSMUST00000089449.2
monoglyceride lipase
chr1_+_143640664 0.22 ENSMUST00000038252.2
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
chr19_+_26749726 0.20 ENSMUST00000175842.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr12_+_59129720 0.20 ENSMUST00000175912.1
ENSMUST00000176892.1
CTAGE family, member 5
chr1_+_180330470 0.19 ENSMUST00000070181.6
inositol 1,4,5-trisphosphate 3-kinase B
chr4_+_95967205 0.19 ENSMUST00000030306.7
hook homolog 1 (Drosophila)
chr16_+_36184082 0.18 ENSMUST00000114858.1
predicted gene 5483
chr6_+_86526271 0.18 ENSMUST00000180896.1
RIKEN cDNA 1600020E01 gene
chr1_-_86111970 0.17 ENSMUST00000027431.6
5-hydroxytryptamine (serotonin) receptor 2B
chr4_-_119383732 0.17 ENSMUST00000044781.2
ENSMUST00000084307.3
coiled-coil domain containing 30
chr18_-_22850738 0.16 ENSMUST00000092015.4
ENSMUST00000069215.6
nucleolar protein 4
chr2_+_126034967 0.15 ENSMUST00000110442.1
fibroblast growth factor 7
chr9_-_96752822 0.14 ENSMUST00000152594.1
zinc finger and BTB domain containing 38
chr5_-_31220491 0.14 ENSMUST00000031032.7
protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform
chr1_+_180111339 0.13 ENSMUST00000145181.1
CDC42 binding protein kinase alpha
chr1_+_20730903 0.11 ENSMUST00000027061.4
interleukin 17A
chr6_-_14755250 0.10 ENSMUST00000045096.4
protein phosphatase 1, regulatory (inhibitor) subunit 3A
chr14_+_66635251 0.09 ENSMUST00000159365.1
ENSMUST00000054661.1
ENSMUST00000159068.1
adrenergic receptor, alpha 1a
chr12_+_74297474 0.09 ENSMUST00000072100.3
DNA binding protein with his-thr domain
chr15_-_13173607 0.08 ENSMUST00000036439.4
cadherin 6
chr1_+_60746358 0.08 ENSMUST00000027165.2
CD28 antigen
chrX_-_94366777 0.06 ENSMUST00000044989.5
RIKEN cDNA 4932442L08 gene
chr10_-_107912134 0.06 ENSMUST00000165341.3
otogelin-like
chr14_-_54966570 0.04 ENSMUST00000124930.1
ENSMUST00000134256.1
ENSMUST00000081857.6
ENSMUST00000145322.1
myosin, heavy polypeptide 6, cardiac muscle, alpha
chr19_-_5797410 0.04 ENSMUST00000173314.1
metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA)
chr6_-_86526164 0.02 ENSMUST00000053015.5
poly(rC) binding protein 1
chr9_-_112187766 0.00 ENSMUST00000111872.2
ENSMUST00000164754.2
cyclic AMP-regulated phosphoprotein, 21
chrX_+_136822671 0.00 ENSMUST00000033800.6
proteolipid protein (myelin) 1

Network of associatons between targets according to the STRING database.

First level regulatory network of Cdc5l

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.3 GO:0003147 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713) cellular response to folic acid(GO:0071231)
0.1 0.3 GO:0035801 adrenal cortex development(GO:0035801) adrenal cortex formation(GO:0035802) negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.1 0.6 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.1 0.3 GO:0006572 tyrosine catabolic process(GO:0006572)
0.1 0.2 GO:0007208 phospholipase C-activating serotonin receptor signaling pathway(GO:0007208)
0.1 0.4 GO:0097647 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.1 0.2 GO:0061033 secretion by lung epithelial cell involved in lung growth(GO:0061033)
0.0 0.2 GO:0033030 negative regulation of neutrophil apoptotic process(GO:0033030)
0.0 0.2 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.0 0.1 GO:0001983 baroreceptor response to increased systemic arterial blood pressure(GO:0001983)
0.0 0.2 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.1 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.0 0.2 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.0 0.4 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.3 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.1 0.7 GO:0045098 type III intermediate filament(GO:0045098)
0.0 0.6 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.2 GO:0070695 FHF complex(GO:0070695)
0.0 0.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.2 GO:0043196 varicosity(GO:0043196)
0.0 0.2 GO:0071564 npBAF complex(GO:0071564)
0.0 0.3 GO:0005614 interstitial matrix(GO:0005614)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.3 GO:0051870 methotrexate binding(GO:0051870)
0.1 0.7 GO:0004850 uridine phosphorylase activity(GO:0004850)
0.1 0.3 GO:0080130 L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.1 0.6 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 0.2 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.1 0.4 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.2 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.1 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.2 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.0 0.3 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.4 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.2 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993) serotonin binding(GO:0051378)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.4 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.6 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.2 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.4 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.4 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.2 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis