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12D miR HR13_24

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Results for Nkx3-2

Z-value: 1.84

Motif logo

Transcription factors associated with Nkx3-2

Gene Symbol Gene ID Gene Info
ENSMUSG00000049691.7 NK3 homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nkx3-2mm10_v2_chr5_-_41764493_417644960.557.8e-02Click!

Activity profile of Nkx3-2 motif

Sorted Z-values of Nkx3-2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr8_+_75213944 7.36 ENSMUST00000139848.1
RASD family, member 2
chr8_+_75214502 6.63 ENSMUST00000132133.1
RASD family, member 2
chr9_-_21037775 5.12 ENSMUST00000180870.1
predicted gene, 26592
chrX_-_102252154 4.59 ENSMUST00000050551.3
Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1
chr4_-_129121699 4.17 ENSMUST00000135763.1
ENSMUST00000149763.1
ENSMUST00000164649.1
hippocalcin
chr6_-_85513586 3.75 ENSMUST00000095759.3
early growth response 4
chr11_+_120949053 2.79 ENSMUST00000154187.1
ENSMUST00000100130.3
ENSMUST00000129473.1
ENSMUST00000168579.1
solute carrier family 16 (monocarboxylic acid transporters), member 3
chr11_+_120948480 2.71 ENSMUST00000070653.6
solute carrier family 16 (monocarboxylic acid transporters), member 3
chr17_-_34627365 2.66 ENSMUST00000064953.8
ENSMUST00000170345.1
ENSMUST00000171121.2
ENSMUST00000168391.2
ENSMUST00000169067.2
palmitoyl-protein thioesterase 2
chr8_-_4779513 2.65 ENSMUST00000022945.7
Shc SH2-domain binding protein 1
chr2_+_3713478 2.64 ENSMUST00000115053.2
family with sequence similarity 107, member B
chr11_-_35798884 2.60 ENSMUST00000160726.2
fibrillarin-like 1
chr19_-_10101501 2.60 ENSMUST00000025567.7
fatty acid desaturase 2
chr13_-_19619820 2.56 ENSMUST00000002885.6
ependymin related protein 1 (zebrafish)
chr3_-_33143227 2.52 ENSMUST00000108219.1
peroxisomal biogenesis factor 5-like
chr2_+_25054396 2.30 ENSMUST00000102931.4
ENSMUST00000074422.7
ENSMUST00000132172.1
ENSMUST00000114388.1
ENSMUST00000114386.1
NMDA receptor synaptonuclear signaling and neuronal migration factor
chr2_+_69670100 2.25 ENSMUST00000100050.3
kelch-like 41
chr1_+_172482199 2.25 ENSMUST00000135267.1
ENSMUST00000052629.6
ENSMUST00000111235.2
immunoglobulin superfamily, member 9
chr17_-_34628005 2.23 ENSMUST00000166040.2
palmitoyl-protein thioesterase 2
chr17_-_45686899 2.13 ENSMUST00000156254.1
transmembrane protein 63b
chr17_-_34628380 1.99 ENSMUST00000167097.2
palmitoyl-protein thioesterase 2
chr2_-_32353283 1.85 ENSMUST00000091089.5
ENSMUST00000113350.1
dynamin 1
chr1_+_161070767 1.85 ENSMUST00000111618.1
ENSMUST00000111620.3
ENSMUST00000028035.7
centromere protein L
chrX_-_97377190 1.73 ENSMUST00000037353.3
ectodysplasin A2 receptor
chr2_+_25054355 1.72 ENSMUST00000100334.4
ENSMUST00000152122.1
ENSMUST00000116574.3
ENSMUST00000006646.8
NMDA receptor synaptonuclear signaling and neuronal migration factor
chr10_+_38965515 1.71 ENSMUST00000019992.5
laminin, alpha 4
chr19_-_34255325 1.70 ENSMUST00000039631.8
actin, alpha 2, smooth muscle, aorta
chr3_-_33143025 1.67 ENSMUST00000108226.1
peroxisomal biogenesis factor 5-like
chr2_-_113848655 1.66 ENSMUST00000102545.1
ENSMUST00000110948.1
Rho GTPase activating protein 11A
chrX_+_110814390 1.66 ENSMUST00000078229.3
POU domain, class 3, transcription factor 4
chr10_+_63100156 1.65 ENSMUST00000044059.3
atonal homolog 7 (Drosophila)
chr11_+_3332426 1.62 ENSMUST00000136474.1
phosphoinositide-3-kinase interacting protein 1
chr7_+_18987518 1.60 ENSMUST00000063563.7
nanos homolog 2 (Drosophila)
chr18_+_5591860 1.59 ENSMUST00000025081.5
ENSMUST00000159390.1
zinc finger E-box binding homeobox 1
chr11_-_101987004 1.58 ENSMUST00000107173.2
ENSMUST00000107172.1
dual specificity phosphatase 3 (vaccinia virus phosphatase VH1-related)
chr8_+_125730005 1.57 ENSMUST00000143504.1
nucleoside-triphosphatase, cancer-related
chr19_-_4877882 1.53 ENSMUST00000006626.3
actinin alpha 3
chr5_-_137858034 1.52 ENSMUST00000110978.2
paired immunoglobin-like type 2 receptor beta 1
chr2_+_32363004 1.51 ENSMUST00000132028.1
ENSMUST00000136079.1
CDKN1A interacting zinc finger protein 1
chr13_-_24761440 1.46 ENSMUST00000176890.1
ENSMUST00000175689.1
geminin
chr7_-_141434402 1.42 ENSMUST00000136354.1
solute carrier family 25 (mitochondrial carrier, glutamate), member 22
chr3_-_108415552 1.40 ENSMUST00000090558.3
cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila)
chrX_-_7947763 1.40 ENSMUST00000154244.1
histone deacetylase 6
chr15_-_103340085 1.39 ENSMUST00000168828.1
zinc finger protein 385A
chr9_+_72806874 1.38 ENSMUST00000055535.8
protogenin homolog (Gallus gallus)
chr19_-_53371766 1.37 ENSMUST00000086887.1
predicted gene 10197
chr19_-_4839286 1.36 ENSMUST00000037246.5
copper chaperone for superoxide dismutase
chr4_-_108032069 1.33 ENSMUST00000106709.2
podocan
chr1_+_172341197 1.28 ENSMUST00000056136.3
potassium inwardly-rectifying channel, subfamily J, member 10
chr2_+_32363163 1.27 ENSMUST00000145635.1
CDKN1A interacting zinc finger protein 1
chrX_+_159414572 1.24 ENSMUST00000112471.2
MAP7 domain containing 2
chr19_+_8740712 1.24 ENSMUST00000163172.1
RIKEN cDNA 1700092M07 gene
chrX_-_7947848 1.20 ENSMUST00000115642.1
ENSMUST00000033501.8
ENSMUST00000145675.1
histone deacetylase 6
chr4_-_108031938 1.19 ENSMUST00000106708.1
podocan
chr3_-_94436574 1.18 ENSMUST00000029787.4
ornithine decarboxylase antizyme 3
chrX_+_153139941 1.17 ENSMUST00000039720.4
ENSMUST00000144175.2
Ras-related GTP binding B
chr16_-_18413452 1.13 ENSMUST00000165430.1
ENSMUST00000147720.1
catechol-O-methyltransferase
chr7_+_6415164 1.11 ENSMUST00000160218.1
small integral membrane protein 17
chr7_+_5057161 1.11 ENSMUST00000045543.5
coiled-coil domain containing 106
chr4_-_131838231 1.09 ENSMUST00000030741.2
ENSMUST00000105987.2
protein tyrosine phosphatase, receptor type, U
chr13_-_98316967 1.09 ENSMUST00000022163.8
ENSMUST00000152704.1
basic transcription factor 3
chr1_-_65032738 1.06 ENSMUST00000162800.1
ENSMUST00000069142.5
aldo-keto reductase family 1, member C-like
chr1_-_161070613 1.05 ENSMUST00000035430.3
aspartyl-tRNA synthetase 2 (mitochondrial)
chr13_-_34963788 1.04 ENSMUST00000164155.1
ENSMUST00000021853.5
enoyl-Coenzyme A delta isomerase 3
chr9_-_43116514 1.01 ENSMUST00000061833.4
transmembrane protein 136
chr3_-_82074639 1.00 ENSMUST00000029635.8
guanylate cyclase 1, soluble, beta 3
chr11_+_87581041 0.98 ENSMUST00000018544.5
ENSMUST00000063156.4
ENSMUST00000107960.1
septin 4
chr2_+_32363192 0.98 ENSMUST00000048964.7
ENSMUST00000113332.1
CDKN1A interacting zinc finger protein 1
chr2_+_11705437 0.98 ENSMUST00000148748.1
interleukin 15 receptor, alpha chain
chr2_-_54085542 0.96 ENSMUST00000100089.2
reprimo, TP53 dependent G2 arrest mediator candidate
chr8_+_45885479 0.96 ENSMUST00000034053.5
PDZ and LIM domain 3
chr11_+_4883186 0.94 ENSMUST00000139737.1
4-nitrophenylphosphatase domain and non-neuronal SNAP25-like protein homolog 1 (C. elegans)
chr4_+_99656299 0.94 ENSMUST00000087285.3
forkhead box D3
chr4_+_130047840 0.92 ENSMUST00000044565.8
ENSMUST00000132251.1
collagen, type XVI, alpha 1
chr2_+_11705459 0.90 ENSMUST00000126394.1
interleukin 15 receptor, alpha chain
chr3_-_80802789 0.89 ENSMUST00000107745.1
ENSMUST00000075316.4
glutamate receptor, ionotropic, AMPA2 (alpha 2)
chr11_+_76202007 0.89 ENSMUST00000094014.3
family with sequence similarity 57, member A
chr7_-_4844665 0.88 ENSMUST00000066041.5
ENSMUST00000172377.1
shisa homolog 7 (Xenopus laevis)
chr13_-_30974023 0.86 ENSMUST00000021785.6
exocyst complex component 2
chr8_-_104631312 0.86 ENSMUST00000034351.6
Ras-related associated with diabetes
chr3_-_95306794 0.83 ENSMUST00000107183.1
ENSMUST00000164406.1
ENSMUST00000123365.1
annexin A9
chr11_+_98927785 0.83 ENSMUST00000107474.1
retinoic acid receptor, alpha
chr19_+_18670780 0.83 ENSMUST00000025632.9
RIKEN cDNA 2410127L17 gene
chr15_+_11064764 0.83 ENSMUST00000061318.7
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 12
chr8_-_56550791 0.83 ENSMUST00000134162.1
ENSMUST00000140107.1
ENSMUST00000040330.8
ENSMUST00000135337.1
centrosomal protein 44
chr2_-_34755229 0.82 ENSMUST00000102800.1
GTPase activating protein and VPS9 domains 1
chr12_-_72408934 0.82 ENSMUST00000078505.7
reticulon 1
chr11_+_70017199 0.82 ENSMUST00000133140.1
discs, large homolog 4 (Drosophila)
chr15_-_56694525 0.82 ENSMUST00000050544.7
hyaluronan synthase 2
chr8_-_109565601 0.82 ENSMUST00000042601.7
DEAH (Asp-Glu-Ala-His) box polypeptide 38
chr2_+_11705287 0.82 ENSMUST00000135341.1
ENSMUST00000138349.1
ENSMUST00000123600.2
interleukin 15 receptor, alpha chain
chr7_-_35556304 0.82 ENSMUST00000040962.5
nudix (nucleoside diphosphate linked moiety X)-type motif 19
chr14_+_51893610 0.79 ENSMUST00000047726.5
ENSMUST00000161888.1
solute carrier family 39 (zinc transporter), member 2
chrX_+_99821021 0.79 ENSMUST00000096363.2
transmembrane protein 28
chr7_-_19359477 0.78 ENSMUST00000047036.8
CD3E antigen, epsilon polypeptide associated protein
chr2_+_32363680 0.78 ENSMUST00000113331.1
ENSMUST00000113338.2
CDKN1A interacting zinc finger protein 1
chr2_+_11705355 0.77 ENSMUST00000128156.2
interleukin 15 receptor, alpha chain
chr5_+_135009152 0.77 ENSMUST00000111216.1
ENSMUST00000046999.8
abhydrolase domain containing 11
chrX_-_7947553 0.76 ENSMUST00000133349.1
histone deacetylase 6
chr2_-_119662756 0.76 ENSMUST00000028768.1
ENSMUST00000110801.1
ENSMUST00000110802.1
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 1
chr4_-_151044564 0.76 ENSMUST00000103204.4
period circadian clock 3
chr8_+_67490758 0.73 ENSMUST00000026677.3
N-acetyl transferase 1
chr11_+_43474276 0.72 ENSMUST00000173002.1
ENSMUST00000057679.3
C1q and tumor necrosis factor related protein 2
chr5_+_90490714 0.72 ENSMUST00000042755.3
alpha fetoprotein
chr2_+_10153563 0.72 ENSMUST00000026886.7
inter-alpha (globulin) inhibitor H5
chr2_+_104027823 0.72 ENSMUST00000111135.1
ENSMUST00000111136.1
ENSMUST00000102565.3
F-box protein 3
chr13_+_44729794 0.72 ENSMUST00000172830.1
jumonji, AT rich interactive domain 2
chr1_-_63730306 0.71 ENSMUST00000114094.2
malate dehydrogenase 1B, NAD (soluble)
chr11_+_3202908 0.71 ENSMUST00000179770.1
ENSMUST00000110048.1
eukaryotic translation initiation factor 4E nuclear import factor 1
chr7_+_80269632 0.70 ENSMUST00000032749.5
vacuolar protein sorting 33B (yeast)
chr3_-_95307132 0.69 ENSMUST00000015846.2
annexin A9
chr6_+_113472276 0.69 ENSMUST00000147316.1
interleukin 17 receptor C
chr4_-_141598206 0.68 ENSMUST00000131317.1
ENSMUST00000006381.4
ENSMUST00000129602.1
filamin binding LIM protein 1
chr11_+_70017085 0.67 ENSMUST00000108589.2
discs, large homolog 4 (Drosophila)
chr9_+_123150941 0.65 ENSMUST00000026890.4
C-type lectin domain family 3, member b
chr17_-_46674255 0.64 ENSMUST00000024766.6
ribosomal RNA processing 36 homolog (S. cerevisiae)
chr13_+_99344775 0.64 ENSMUST00000052249.5
mitochondrial ribosomal protein S27
chr16_+_44347121 0.64 ENSMUST00000050897.6
spindle and centriole associated protein 1
chr7_-_67759735 0.63 ENSMUST00000074233.4
ENSMUST00000051389.8
synemin, intermediate filament protein
chr16_-_19200350 0.63 ENSMUST00000103749.2
immunoglobulin lambda constant 2
chr11_-_120731944 0.62 ENSMUST00000154565.1
ENSMUST00000026148.2
carbonyl reductase 2
chr9_+_40269430 0.62 ENSMUST00000171835.2
sodium channel, voltage-gated, type III, beta
chr6_-_124863877 0.62 ENSMUST00000046893.7
G protein-coupled receptor 162
chr5_-_139130159 0.61 ENSMUST00000129851.1
protein kinase, cAMP dependent regulatory, type I beta
chrX_-_48674478 0.60 ENSMUST00000053970.3
G-protein coupled receptor 119
chr16_+_14705832 0.59 ENSMUST00000023356.6
snail homolog 2 (Drosophila)
chr4_-_133872304 0.59 ENSMUST00000157067.2
ribosomal protein S6 kinase polypeptide 1
chrX_+_134059315 0.57 ENSMUST00000144483.1
cleavage stimulation factor, 3' pre-RNA subunit 2
chrX_+_57043074 0.57 ENSMUST00000033464.3
bombesin-like receptor 3
chr18_-_62179948 0.56 ENSMUST00000053640.3
adrenergic receptor, beta 2
chr4_+_53631460 0.56 ENSMUST00000179534.1
ENSMUST00000132151.1
fibronectin type III and SPRY domain containing 1-like
chr4_+_55350043 0.56 ENSMUST00000030134.8
RAD23b homolog (S. cerevisiae)
chr2_+_104027721 0.55 ENSMUST00000028603.3
F-box protein 3
chrX_+_166170449 0.55 ENSMUST00000130880.2
ENSMUST00000056410.4
ENSMUST00000096252.3
ENSMUST00000087169.4
gem (nuclear organelle) associated protein 8
chr10_+_79879614 0.55 ENSMUST00000006679.8
proteinase 3
chr4_+_130360132 0.54 ENSMUST00000105994.3
small nuclear ribonucleoprotein 40 (U5)
chr6_+_83034173 0.54 ENSMUST00000000707.2
ENSMUST00000101257.3
lysyl oxidase-like 3
chr11_+_50237002 0.54 ENSMUST00000180443.1
predicted gene, 26542
chr9_-_57158288 0.54 ENSMUST00000065358.7
COMM domain containing 4
chr9_-_108094459 0.54 ENSMUST00000081309.7
acylpeptide hydrolase
chr9_-_86464944 0.54 ENSMUST00000034986.7
ubiquitin-conjugating enzyme E2C binding protein
chr1_+_139422196 0.53 ENSMUST00000039867.7
zinc finger and BTB domain containing 41 homolog
chr2_-_166581969 0.53 ENSMUST00000109246.1
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
chr18_+_73863672 0.52 ENSMUST00000134847.1
maestro
chr9_-_86464900 0.52 ENSMUST00000121189.1
ubiquitin-conjugating enzyme E2C binding protein
chr19_+_41593363 0.50 ENSMUST00000099454.3
expressed sequence AI606181
chr3_-_37419566 0.50 ENSMUST00000138949.1
ENSMUST00000149449.1
ENSMUST00000108117.2
ENSMUST00000108118.2
ENSMUST00000099130.2
ENSMUST00000052645.6
nudix (nucleoside diphosphate linked moiety X)-type motif 6
chr7_+_140920940 0.49 ENSMUST00000184560.1
NLR family, pyrin domain containing 6
chr8_-_112011266 0.49 ENSMUST00000164470.1
ENSMUST00000093120.5
lysyl-tRNA synthetase
chr2_+_35691893 0.49 ENSMUST00000065001.5
disabled 2 interacting protein
chr8_-_112011320 0.47 ENSMUST00000034426.6
lysyl-tRNA synthetase
chr4_-_56802265 0.45 ENSMUST00000030140.2
inhibitor of kappa light polypeptide enhancer in B cells, kinase complex-associated protein
chr16_+_22892035 0.45 ENSMUST00000023583.5
alpha-2-HS-glycoprotein
chr4_+_130047914 0.44 ENSMUST00000142293.1
collagen, type XVI, alpha 1
chr14_-_20269162 0.42 ENSMUST00000024155.7
potassium channel, subfamily K, member 16
chr16_-_31081363 0.41 ENSMUST00000055389.7
xyloside xylosyltransferase 1
chr5_-_100674230 0.40 ENSMUST00000031262.7
coenzyme Q2 homolog, prenyltransferase (yeast)
chr7_-_24587612 0.40 ENSMUST00000094705.2
zinc finger protein 575
chr2_+_130424321 0.39 ENSMUST00000128994.1
ENSMUST00000028900.9
vacuolar protein sorting 16 (yeast)
chr1_-_160077918 0.38 ENSMUST00000028061.3
RIKEN cDNA 4930562F07 gene
chr7_-_110982443 0.38 ENSMUST00000005751.6
MRV integration site 1
chrX_-_136741155 0.38 ENSMUST00000166930.1
ENSMUST00000113095.1
ENSMUST00000155207.1
ENSMUST00000080411.6
ENSMUST00000169418.1
mortality factor 4 like 2
chr3_-_57575760 0.37 ENSMUST00000029380.7
WW domain containing transcription regulator 1
chr10_+_42860348 0.37 ENSMUST00000063063.7
sex comb on midleg-like 4 (Drosophila)
chr13_+_44729535 0.37 ENSMUST00000174068.1
jumonji, AT rich interactive domain 2
chr12_+_111039334 0.36 ENSMUST00000084968.7
REST corepressor 1
chr13_-_92483996 0.36 ENSMUST00000040106.7
family with sequence similarity 151, member B
chr14_-_119099399 0.36 ENSMUST00000156203.1
UDP-glucose glycoprotein glucosyltransferase 2
chr2_+_158794807 0.35 ENSMUST00000029186.7
ENSMUST00000109478.2
ENSMUST00000156893.1
DEAH (Asp-Glu-Ala-His) box polypeptide 35
chr1_+_91366412 0.35 ENSMUST00000086861.5
family with sequence similarity 132, member B
chr4_-_40948196 0.35 ENSMUST00000030125.4
ENSMUST00000108089.1
BCL2-associated athanogene 1
chr7_+_125829653 0.35 ENSMUST00000124223.1
RIKEN cDNA D430042O09 gene
chr11_-_100620165 0.35 ENSMUST00000014339.8
DnaJ (Hsp40) homolog, subfamily C, member 7
chr4_+_126096623 0.34 ENSMUST00000055575.7
ENSMUST00000179323.1
ENSMUST00000151831.1
U7 snRNP-specific Sm-like protein LSM10
chr15_+_75596645 0.33 ENSMUST00000023243.4
GPI-anchored HDL-binding protein 1
chr11_-_100619576 0.33 ENSMUST00000155152.1
DnaJ (Hsp40) homolog, subfamily C, member 7
chr7_+_30280094 0.32 ENSMUST00000108187.1
ENSMUST00000014072.5
THAP domain containing 8
chr15_-_66969616 0.32 ENSMUST00000170903.1
ENSMUST00000166420.1
ENSMUST00000005256.6
ENSMUST00000164070.1
N-myc downstream regulated gene 1
chr7_+_92741603 0.32 ENSMUST00000032879.7
RAB30, member RAS oncogene family
chr13_+_23782572 0.31 ENSMUST00000074067.2
tripartite motif-containing 38
chr3_+_88142328 0.31 ENSMUST00000001455.6
ENSMUST00000119251.1
myocyte enhancer factor 2D
chr15_+_98092569 0.31 ENSMUST00000163507.1
phosphofructokinase, muscle
chr10_-_67285180 0.30 ENSMUST00000159002.1
ENSMUST00000077839.6
nuclear receptor binding factor 2
chr1_+_63730614 0.30 ENSMUST00000027103.6
FAST kinase domains 2
chr19_+_24999500 0.30 ENSMUST00000025831.6
dedicator of cytokinesis 8
chr17_+_34031787 0.29 ENSMUST00000044858.8
retinoid X receptor beta
chr1_-_193130201 0.29 ENSMUST00000085555.1
digestive organ expansion factor homolog (zebrafish)
chr9_-_106199253 0.29 ENSMUST00000140761.1
protein phosphatase 1M
chr3_+_157534103 0.29 ENSMUST00000106058.1
zinc finger, RAN-binding domain containing 2
chr10_+_128092771 0.29 ENSMUST00000170054.2
ENSMUST00000045621.8
bromodomain adjacent to zinc finger domain, 2A
chr1_-_88008520 0.29 ENSMUST00000040783.4
ubiquitin specific peptidase 40
chr1_-_74588117 0.29 ENSMUST00000066986.6
zinc finger protein 142
chr8_+_104101625 0.28 ENSMUST00000034339.8
cadherin 5
chr19_-_10881677 0.28 ENSMUST00000128835.1
transmembrane protein 109
chr11_+_97703394 0.28 ENSMUST00000103147.4
proteasome (prosome, macropain) subunit, beta type 3
chr5_+_64230285 0.28 ENSMUST00000119756.1
TBC1 domain family, member 1
chr10_-_128919259 0.27 ENSMUST00000149961.1
ENSMUST00000026406.7
retinol dehydrogenase 5
chr2_-_164404606 0.27 ENSMUST00000109359.1
ENSMUST00000109358.1
ENSMUST00000103103.3
matrilin 4
chr11_-_69795930 0.26 ENSMUST00000045971.8
cholinergic receptor, nicotinic, beta polypeptide 1 (muscle)
chr18_-_80934054 0.26 ENSMUST00000091790.3
ATPase, class II, type 9B

Network of associatons between targets according to the STRING database.

First level regulatory network of Nkx3-2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.2 GO:0031283 negative regulation of cGMP metabolic process(GO:0030824) negative regulation of cGMP biosynthetic process(GO:0030827) negative regulation of guanylate cyclase activity(GO:0031283)
1.1 3.4 GO:0070844 misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846)
1.0 4.0 GO:0099527 postsynapse to nucleus signaling pathway(GO:0099527)
0.9 4.6 GO:0071104 response to interleukin-9(GO:0071104) response to interleukin-11(GO:0071105)
0.9 4.5 GO:0032298 positive regulation of DNA-dependent DNA replication initiation(GO:0032298)
0.6 5.5 GO:0015727 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.5 2.2 GO:0031443 fast-twitch skeletal muscle fiber contraction(GO:0031443)
0.5 4.2 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
0.5 2.1 GO:0070889 platelet alpha granule organization(GO:0070889)
0.5 2.6 GO:0018364 peptidyl-glutamine methylation(GO:0018364)
0.5 14.0 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.4 1.1 GO:0031335 regulation of sulfur amino acid metabolic process(GO:0031335)
0.3 1.0 GO:0099543 trans-synaptic signaling by soluble gas(GO:0099543)
0.3 1.0 GO:0045575 basophil activation involved in immune response(GO:0002276) basophil activation(GO:0045575)
0.3 1.3 GO:0051935 amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
0.3 2.1 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.3 1.2 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.3 2.3 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.3 1.4 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.3 0.8 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.3 0.8 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.3 1.1 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.3 1.8 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.2 1.6 GO:0044838 cell quiescence(GO:0044838)
0.2 0.9 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.2 0.8 GO:1902202 proteoglycan catabolic process(GO:0030167) regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202) negative regulation of cellular response to vascular endothelial growth factor stimulus(GO:1902548)
0.2 0.6 GO:1901420 negative regulation of response to alcohol(GO:1901420)
0.2 0.6 GO:0000715 nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.2 2.3 GO:0031272 regulation of pseudopodium assembly(GO:0031272)
0.1 1.6 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.1 0.9 GO:0001927 exocyst assembly(GO:0001927)
0.1 0.6 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.1 1.0 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.1 3.5 GO:0032825 positive regulation of natural killer cell differentiation(GO:0032825)
0.1 1.6 GO:0021554 optic nerve development(GO:0021554)
0.1 0.5 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)
0.1 1.5 GO:0098953 receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628)
0.1 1.7 GO:2001054 negative regulation of mesenchymal cell apoptotic process(GO:2001054)
0.1 1.2 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.1 0.5 GO:2000320 negative regulation of T-helper 17 type immune response(GO:2000317) negative regulation of T-helper 17 cell differentiation(GO:2000320)
0.1 0.6 GO:0006116 NADH oxidation(GO:0006116)
0.1 0.6 GO:0072307 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.1 1.0 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.1 0.3 GO:0010986 positive regulation of lipoprotein particle clearance(GO:0010986)
0.1 1.1 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.1 0.7 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.1 1.6 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.1 0.6 GO:0060371 regulation of atrial cardiac muscle cell membrane depolarization(GO:0060371) regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.1 2.0 GO:0033622 integrin activation(GO:0033622)
0.1 0.7 GO:0070933 histone H4 deacetylation(GO:0070933)
0.1 0.3 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.1 0.4 GO:0016266 O-glycan processing(GO:0016266)
0.1 0.2 GO:0048691 positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) positive regulation of retinal ganglion cell axon guidance(GO:1902336)
0.1 0.2 GO:0033575 protein glycosylation at cell surface(GO:0033575) protein galactosylation at cell surface(GO:0033580) protein galactosylation(GO:0042125)
0.1 0.7 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.1 1.3 GO:0015813 L-glutamate transport(GO:0015813)
0.1 0.4 GO:0055069 zinc ion homeostasis(GO:0055069)
0.1 0.3 GO:0061622 glycolytic process through glucose-1-phosphate(GO:0061622)
0.0 0.2 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.0 1.3 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.0 0.7 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.0 0.6 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.4 GO:0006071 glycerol metabolic process(GO:0006071)
0.0 0.4 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 0.5 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 0.3 GO:1903142 blood vessel maturation(GO:0001955) positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.0 0.2 GO:0009838 abscission(GO:0009838)
0.0 0.2 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.0 0.2 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
0.0 0.5 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0 0.8 GO:0045187 regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.0 0.1 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.0 0.2 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.0 0.7 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.0 0.2 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.2 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.4 GO:0060087 relaxation of vascular smooth muscle(GO:0060087)
0.0 0.3 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.0 0.2 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.6 GO:0046599 regulation of centriole replication(GO:0046599)
0.0 2.5 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.3 GO:0090232 positive regulation of spindle checkpoint(GO:0090232)
0.0 0.4 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 1.5 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.2 GO:0001302 replicative cell aging(GO:0001302)
0.0 0.6 GO:0000469 cleavage involved in rRNA processing(GO:0000469)
0.0 0.5 GO:0046321 positive regulation of fatty acid oxidation(GO:0046321)
0.0 0.8 GO:0009303 rRNA transcription(GO:0009303)
0.0 0.3 GO:0001771 immunological synapse formation(GO:0001771)
0.0 0.0 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.0 0.0 GO:2000820 negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000820)
0.0 0.4 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 0.3 GO:0035095 behavioral response to nicotine(GO:0035095)
0.0 0.7 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 1.5 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.0 0.7 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 1.4 GO:0006801 superoxide metabolic process(GO:0006801)
0.0 0.4 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.8 GO:0006829 zinc II ion transport(GO:0006829)
0.0 0.4 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.3 GO:0072600 establishment of protein localization to Golgi(GO:0072600)
0.0 0.6 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 0.1 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.0 0.4 GO:0045780 positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.0 0.6 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.0 1.8 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0 2.5 GO:0007605 sensory perception of sound(GO:0007605)
0.0 0.6 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.1 GO:0034058 endosomal vesicle fusion(GO:0034058) positive regulation of pinocytosis(GO:0048549)
0.0 0.0 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.0 0.1 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 1.1 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.0 GO:1902277 negative regulation of pancreatic amylase secretion(GO:1902277)
0.0 0.0 GO:0097021 lymphocyte migration into lymphoid organs(GO:0097021)
0.0 0.2 GO:0007413 axonal fasciculation(GO:0007413)
0.0 0.7 GO:0034394 protein localization to cell surface(GO:0034394)
0.0 0.3 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.5 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.0 0.0 GO:0070813 hydrogen sulfide metabolic process(GO:0070813)
0.0 2.0 GO:0007160 cell-matrix adhesion(GO:0007160)
0.0 1.0 GO:2000177 regulation of neural precursor cell proliferation(GO:2000177)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 4.2 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.4 2.6 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.3 4.2 GO:0044327 dendritic spine head(GO:0044327)
0.2 1.7 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.2 1.2 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.2 0.6 GO:0071920 cleavage body(GO:0071920)
0.1 0.6 GO:0071942 XPC complex(GO:0071942)
0.1 2.3 GO:0031143 pseudopodium(GO:0031143)
0.1 0.5 GO:1990032 parallel fiber(GO:1990032)
0.1 1.0 GO:0097227 sperm annulus(GO:0097227)
0.1 0.7 GO:0001652 granular component(GO:0001652)
0.1 1.5 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 4.0 GO:0097440 apical dendrite(GO:0097440)
0.1 1.3 GO:0097449 astrocyte projection(GO:0097449)
0.1 1.9 GO:0043196 varicosity(GO:0043196)
0.1 1.1 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.1 0.6 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.1 0.3 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.1 0.3 GO:0005683 U7 snRNP(GO:0005683)
0.1 1.7 GO:0005605 basal lamina(GO:0005605)
0.1 3.4 GO:0016235 aggresome(GO:0016235)
0.1 0.2 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.1 0.5 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 0.6 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 1.0 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.1 0.2 GO:0036125 mitochondrial fatty acid beta-oxidation multienzyme complex(GO:0016507) fatty acid beta-oxidation multienzyme complex(GO:0036125)
0.1 2.2 GO:0060077 inhibitory synapse(GO:0060077)
0.1 0.3 GO:0033553 rDNA heterochromatin(GO:0033553)
0.1 0.6 GO:0032797 SMN complex(GO:0032797)
0.1 0.3 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.8 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 1.8 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 1.1 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.9 GO:0000145 exocyst(GO:0000145)
0.0 1.0 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.6 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 1.4 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 0.7 GO:0005682 U5 snRNP(GO:0005682)
0.0 1.6 GO:0001772 immunological synapse(GO:0001772)
0.0 0.2 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 0.4 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.3 GO:0032040 small-subunit processome(GO:0032040)
0.0 0.2 GO:0042629 mast cell granule(GO:0042629)
0.0 0.4 GO:0061702 inflammasome complex(GO:0061702)
0.0 0.8 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 5.4 GO:0031965 nuclear membrane(GO:0031965)
0.0 1.7 GO:0005581 collagen trimer(GO:0005581)
0.0 2.0 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.3 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.6 GO:0030686 90S preribosome(GO:0030686)
0.0 0.4 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 0.3 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.1 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.3 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.2 GO:0090543 Flemming body(GO:0090543)
0.0 0.6 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 1.5 GO:0072562 blood microparticle(GO:0072562)
0.0 1.3 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 0.2 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.1 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.4 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.1 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 5.9 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.4 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.8 5.5 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.7 4.2 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.7 6.9 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.6 14.0 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.5 2.6 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768)
0.4 1.3 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.4 1.1 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.3 4.6 GO:0050693 LBD domain binding(GO:0050693)
0.3 1.2 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.3 1.4 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.3 1.6 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.3 0.8 GO:0015275 stretch-activated, cation-selective, calcium channel activity(GO:0015275)
0.2 0.7 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.2 0.7 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.2 0.8 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.2 0.6 GO:0004946 bombesin receptor activity(GO:0004946)
0.2 1.5 GO:0031812 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.2 0.7 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.2 0.9 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.2 2.6 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.2 0.7 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.2 1.6 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.2 0.6 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.1 0.6 GO:0004939 beta-adrenergic receptor activity(GO:0004939) bradykinin receptor binding(GO:0031711)
0.1 5.6 GO:0030332 cyclin binding(GO:0030332)
0.1 0.3 GO:0071208 histone pre-mRNA DCP binding(GO:0071208) U7 snRNA binding(GO:0071209)
0.1 1.4 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.1 0.5 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 1.7 GO:0003680 AT DNA binding(GO:0003680)
0.1 1.6 GO:0033549 MAP kinase phosphatase activity(GO:0033549)
0.1 0.4 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.1 0.6 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.1 0.7 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.1 1.8 GO:0015464 acetylcholine receptor activity(GO:0015464)
0.1 0.8 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 0.3 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.1 1.5 GO:0042288 MHC class I protein binding(GO:0042288)
0.1 0.5 GO:0005000 vasopressin receptor activity(GO:0005000)
0.1 0.4 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.1 0.9 GO:0042165 neurotransmitter binding(GO:0042165)
0.1 0.2 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.1 0.5 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.1 1.0 GO:0004016 adenylate cyclase activity(GO:0004016)
0.1 0.5 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.1 0.2 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.1 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 0.3 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.6 GO:0017166 vinculin binding(GO:0017166)
0.0 0.4 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.2 GO:0016509 long-chain-enoyl-CoA hydratase activity(GO:0016508) long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0 0.3 GO:0035473 lipase binding(GO:0035473)
0.0 0.2 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 4.0 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.4 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.9 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.2 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.0 0.8 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.2 GO:0047276 N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
0.0 0.6 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.1 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 2.0 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.3 GO:0034511 U3 snoRNA binding(GO:0034511)
0.0 1.8 GO:0016876 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 0.5 GO:0008242 omega peptidase activity(GO:0008242)
0.0 0.3 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.4 GO:0004659 prenyltransferase activity(GO:0004659)
0.0 1.0 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.9 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 1.6 GO:0070888 E-box binding(GO:0070888)
0.0 0.6 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.0 0.7 GO:0031005 filamin binding(GO:0031005)
0.0 0.2 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.4 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 2.1 GO:0005518 collagen binding(GO:0005518)
0.0 0.8 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 1.2 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.2 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.2 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.2 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.1 GO:0004738 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.0 0.6 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.3 GO:0001164 RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.0 0.0 GO:0035939 microsatellite binding(GO:0035939)
0.0 0.7 GO:0032452 histone demethylase activity(GO:0032452)
0.0 1.4 GO:0002039 p53 binding(GO:0002039)
0.0 0.5 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 1.2 GO:0003724 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.2 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.1 GO:0070492 sialic acid binding(GO:0033691) oligosaccharide binding(GO:0070492)
0.0 0.3 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.3 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.6 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.6 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 1.1 GO:0005178 integrin binding(GO:0005178)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.1 2.5 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 3.7 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.1 1.9 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 3.2 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 1.5 ST GA12 PATHWAY G alpha 12 Pathway
0.0 1.4 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 4.6 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 1.1 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.6 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 1.5 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.9 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 1.4 NABA COLLAGENS Genes encoding collagen proteins
0.0 1.4 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 0.3 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 0.9 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.3 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 1.2 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.2 PID AP1 PATHWAY AP-1 transcription factor network
0.0 2.0 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.5 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.4 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 1.8 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.3 PID RHODOPSIN PATHWAY Visual signal transduction: Rods

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 5.5 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.2 0.6 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.1 2.6 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.1 1.6 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.1 1.8 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.1 2.0 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.1 1.5 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 0.8 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 3.5 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 1.9 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.8 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.9 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.9 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.4 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.6 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.9 REACTOME PROCESSING OF CAPPED INTRONLESS PRE MRNA Genes involved in Processing of Capped Intronless Pre-mRNA
0.0 1.4 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.0 0.8 REACTOME CLEAVAGE OF GROWING TRANSCRIPT IN THE TERMINATION REGION Genes involved in Cleavage of Growing Transcript in the Termination Region
0.0 0.4 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.7 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 1.5 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.3 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 0.6 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 0.8 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.3 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 1.8 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.5 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 1.1 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.0 0.6 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.6 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.4 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 1.0 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.6 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import