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12D miR HR13_24

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Results for Gata6

Z-value: 0.33

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Transcription factors associated with Gata6

Gene Symbol Gene ID Gene Info
ENSMUSG00000005836.8 GATA binding protein 6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Gata6mm10_v2_chr18_+_11052487_110525100.501.2e-01Click!

Activity profile of Gata6 motif

Sorted Z-values of Gata6 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr9_+_46228580 0.98 ENSMUST00000034588.8
apolipoprotein A-I
chr5_+_76840597 0.52 ENSMUST00000120639.2
ENSMUST00000163347.1
ENSMUST00000121851.1
RIKEN cDNA C530008M17 gene
chr2_+_72476159 0.39 ENSMUST00000102691.4
cell division cycle associated 7
chr7_-_139582790 0.36 ENSMUST00000106095.2
NK6 homeobox 2
chr2_+_72476225 0.31 ENSMUST00000157019.1
cell division cycle associated 7
chr2_-_172370506 0.31 ENSMUST00000109139.1
ENSMUST00000028997.7
ENSMUST00000109140.3
aurora kinase A
chr11_+_70505244 0.30 ENSMUST00000019063.2
transmembrane 4 superfamily member 5
chr11_+_3330781 0.28 ENSMUST00000136536.1
ENSMUST00000093399.4
phosphoinositide-3-kinase interacting protein 1
chr2_-_33087169 0.28 ENSMUST00000102810.3
GTPase activating RANGAP domain-like 3
chr2_-_33086366 0.24 ENSMUST00000049618.2
GTPase activating RANGAP domain-like 3
chr7_-_99238564 0.24 ENSMUST00000064231.7
monoacylglycerol O-acyltransferase 2
chr2_+_163547148 0.21 ENSMUST00000109411.1
ENSMUST00000018094.6
hepatic nuclear factor 4, alpha
chr5_-_125294107 0.20 ENSMUST00000127148.1
scavenger receptor class B, member 1
chr2_-_17460610 0.19 ENSMUST00000145492.1
nebulette
chr17_+_71204647 0.18 ENSMUST00000126681.1
lipin 2
chr10_+_40883469 0.18 ENSMUST00000019975.7
WAS protein family, member 1
chr11_+_4883186 0.18 ENSMUST00000139737.1
4-nitrophenylphosphatase domain and non-neuronal SNAP25-like protein homolog 1 (C. elegans)
chr7_+_88278085 0.17 ENSMUST00000032779.5
ENSMUST00000128791.1
cathepsin C
chr7_-_135528645 0.17 ENSMUST00000053716.7
clarin 3
chr4_+_11579647 0.15 ENSMUST00000180239.1
fibrinogen silencer binding protein
chr2_-_126783416 0.15 ENSMUST00000130356.1
ENSMUST00000028842.2
ubiquitin specific peptidase 50
chr6_+_86078070 0.14 ENSMUST00000032069.5
adducin 2 (beta)
chr6_-_136875794 0.13 ENSMUST00000032342.1
matrix Gla protein
chr14_-_70524068 0.13 ENSMUST00000022692.3
surfactant associated protein C
chr8_+_45628176 0.12 ENSMUST00000130850.1
sorbin and SH3 domain containing 2
chr2_+_68104671 0.12 ENSMUST00000042456.3
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr10_+_53337686 0.12 ENSMUST00000046221.6
ENSMUST00000163319.1
phospholamban
chr1_-_14310198 0.12 ENSMUST00000168081.2
ENSMUST00000027066.6
eyes absent 1 homolog (Drosophila)
chr11_+_98026695 0.12 ENSMUST00000092425.4
ribosomal protein L19
chr1_-_144775419 0.12 ENSMUST00000027603.3
regulator of G-protein signaling 18
chr1_-_173333503 0.12 ENSMUST00000038227.4
Duffy blood group, chemokine receptor
chr3_-_20242173 0.11 ENSMUST00000001921.1
carboxypeptidase A3, mast cell
chr11_+_98026918 0.11 ENSMUST00000017548.6
ribosomal protein L19
chr1_+_179803376 0.11 ENSMUST00000097454.2
predicted gene 10518
chr3_-_75270073 0.11 ENSMUST00000039047.4
serine (or cysteine) peptidase inhibitor, clade I, member 2
chr11_-_102365111 0.10 ENSMUST00000006749.9
solute carrier family 4 (anion exchanger), member 1
chrX_+_7579666 0.10 ENSMUST00000115740.1
ENSMUST00000115739.1
forkhead box P3
chr4_+_136143497 0.10 ENSMUST00000008016.2
inhibitor of DNA binding 3
chr1_+_45311538 0.09 ENSMUST00000087883.6
collagen, type III, alpha 1
chr10_+_87861309 0.09 ENSMUST00000122100.1
insulin-like growth factor 1
chr19_-_42202150 0.09 ENSMUST00000018966.7
secreted frizzled-related sequence protein 5
chr8_-_36953139 0.09 ENSMUST00000179501.1
deleted in liver cancer 1
chr16_-_46010212 0.08 ENSMUST00000130481.1
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr18_-_39489157 0.08 ENSMUST00000131885.1
nuclear receptor subfamily 3, group C, member 1
chr3_-_30140407 0.08 ENSMUST00000108271.3
MDS1 and EVI1 complex locus
chr11_-_53707269 0.08 ENSMUST00000124352.1
ENSMUST00000020649.7
RAD50 homolog (S. cerevisiae)
chr2_+_74704615 0.07 ENSMUST00000151380.1
homeobox D8
chr2_-_59948155 0.07 ENSMUST00000153136.1
bromodomain adjacent to zinc finger domain, 2B
chr18_+_11052487 0.07 ENSMUST00000047762.7
GATA binding protein 6
chr16_-_95459245 0.06 ENSMUST00000176345.1
ENSMUST00000121809.2
ENSMUST00000118113.1
ENSMUST00000122199.1
avian erythroblastosis virus E-26 (v-ets) oncogene related
chr15_-_83170168 0.06 ENSMUST00000162834.1
cytochrome b5 reductase 3
chr9_+_62342449 0.06 ENSMUST00000156461.1
acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
chr4_+_13751297 0.06 ENSMUST00000105566.2
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr2_-_125859139 0.06 ENSMUST00000110463.1
ENSMUST00000028635.5
COP9 (constitutive photomorphogenic) homolog, subunit 2 (Arabidopsis thaliana)
chr9_-_44342332 0.05 ENSMUST00000097558.3
hydroxymethylbilane synthase
chr1_-_144177259 0.05 ENSMUST00000111941.1
ENSMUST00000052375.1
regulator of G-protein signaling 13
chr5_-_73191848 0.05 ENSMUST00000176910.1
furry homolog-like (Drosophila)
chr15_-_83170498 0.05 ENSMUST00000162178.1
cytochrome b5 reductase 3
chr4_+_150148905 0.05 ENSMUST00000059893.7
solute carrier family 2 (facilitated glucose transporter), member 7
chr9_-_29963112 0.05 ENSMUST00000075069.4
neurotrimin
chr11_-_46389471 0.05 ENSMUST00000109237.2
IL2 inducible T cell kinase
chr2_+_172370658 0.05 ENSMUST00000151511.1
ENSMUST00000116375.1
cleavage stimulation factor, 3' pre-RNA, subunit 1
chr11_+_87581041 0.04 ENSMUST00000018544.5
ENSMUST00000063156.4
ENSMUST00000107960.1
septin 4
chr18_+_37300799 0.04 ENSMUST00000051754.1
protocadherin beta 3
chrX_+_10485121 0.04 ENSMUST00000076354.6
ENSMUST00000115526.1
tetraspanin 7
chr11_-_46389509 0.04 ENSMUST00000020664.6
IL2 inducible T cell kinase
chr11_-_70220969 0.04 ENSMUST00000060010.2
solute carrier family 16 (monocarboxylic acid transporters), member 13
chr11_-_99493112 0.04 ENSMUST00000006969.7
keratin 23
chr9_+_66350465 0.03 ENSMUST00000042824.6
hect (homologous to the E6-AP (UBE3A) carboxyl terminus) domain and RCC1 (CHC1)-like domain (RLD) 1
chr4_-_137430517 0.03 ENSMUST00000102522.4
chymotrypsin-like elastase family, member 3B
chr3_+_79885930 0.03 ENSMUST00000029567.8
family with sequence similarity 198, member B
chr17_-_33713372 0.03 ENSMUST00000173392.1
membrane-associated ring finger (C3HC4) 2
chr7_+_119900099 0.03 ENSMUST00000106516.1
LYR motif containing 1
chr6_-_38124568 0.03 ENSMUST00000040259.4
ATPase, H+ transporting, lysosomal V0 subunit A4
chr8_+_45627946 0.02 ENSMUST00000145458.1
sorbin and SH3 domain containing 2
chr5_+_91027457 0.02 ENSMUST00000041516.8
epithelial mitogen
chr4_-_137409777 0.02 ENSMUST00000024200.6
predicted gene 13011
chr10_-_62342674 0.02 ENSMUST00000143179.1
ENSMUST00000130422.1
hexokinase 1
chr7_+_28833975 0.02 ENSMUST00000066723.8
lectin, galactose binding, soluble 4
chr2_-_7081256 0.02 ENSMUST00000183209.1
CUGBP, Elav-like family member 2
chr9_-_65827544 0.02 ENSMUST00000159109.1
zinc finger protein 609
chr10_-_40883073 0.02 ENSMUST00000044166.7
cell division cycle 40
chr16_-_34262945 0.02 ENSMUST00000114953.1
kalirin, RhoGEF kinase
chr13_+_24802020 0.00 ENSMUST00000155575.1
cDNA sequence BC005537
chr8_-_117082449 0.00 ENSMUST00000098375.4
ENSMUST00000109093.2
polycystic kidney disease 1 like 2
chr2_-_7395968 0.00 ENSMUST00000002176.6
CUGBP, Elav-like family member 2
chr2_+_65930117 0.00 ENSMUST00000176109.1
cysteine-serine-rich nuclear protein 3
chr2_-_7081207 0.00 ENSMUST00000114923.2
ENSMUST00000182706.1
CUGBP, Elav-like family member 2

Network of associatons between targets according to the STRING database.

First level regulatory network of Gata6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0002740 negative regulation of cytokine secretion involved in immune response(GO:0002740)
0.1 0.2 GO:0046462 monoacylglycerol metabolic process(GO:0046462)
0.1 0.3 GO:0007056 spindle assembly involved in female meiosis(GO:0007056) positive regulation of oocyte development(GO:0060282)
0.1 0.2 GO:1902569 regulation of activation of JAK2 kinase activity(GO:0010534) activation of JAK2 kinase activity(GO:0042977) negative regulation of activation of JAK2 kinase activity(GO:1902569)
0.1 0.2 GO:0010899 regulation of phosphatidylcholine catabolic process(GO:0010899) lipopolysaccharide transport(GO:0015920)
0.1 0.4 GO:0021912 regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.0 0.3 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.0 0.1 GO:0031064 CD4-positive, CD25-positive, alpha-beta regulatory T cell lineage commitment(GO:0002362) negative regulation of histone deacetylation(GO:0031064) positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032831) negative regulation of interferon-gamma biosynthetic process(GO:0045077)
0.0 0.1 GO:2000040 regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
0.0 0.2 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.0 0.1 GO:0007493 endodermal cell fate determination(GO:0007493)
0.0 0.1 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 0.1 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 0.1 GO:1904075 regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.0 0.1 GO:0000019 regulation of mitotic recombination(GO:0000019) telomeric 3' overhang formation(GO:0031860)
0.0 0.1 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.1 GO:0086023 adrenergic receptor signaling pathway involved in heart process(GO:0086023)
0.0 0.1 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169) negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
0.0 0.1 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.1 0.3 GO:0042585 germinal vesicle(GO:0042585)
0.0 0.2 GO:0031209 SCAR complex(GO:0031209)
0.0 0.1 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.1 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.1 GO:0097208 alveolar lamellar body(GO:0097208)
0.0 0.1 GO:0042567 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867) insulin-like growth factor ternary complex(GO:0042567)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.1 0.2 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.1 0.2 GO:0070540 stearic acid binding(GO:0070540)
0.1 0.3 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.1 0.2 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.0 0.2 GO:1990932 5.8S rRNA binding(GO:1990932)
0.0 0.3 GO:0035174 histone serine kinase activity(GO:0035174)
0.0 0.1 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.0 0.2 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.2 GO:0031404 chloride ion binding(GO:0031404)
0.0 0.1 GO:0038049 glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.1 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.0 0.1 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.3 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.2 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE