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12D miR HR13_24

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Results for Dmc1

Z-value: 1.11

Motif logo

Transcription factors associated with Dmc1

Gene Symbol Gene ID Gene Info
ENSMUSG00000022429.10 DNA meiotic recombinase 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Dmc1mm10_v2_chr15_-_79605084_79605114-0.471.4e-01Click!

Activity profile of Dmc1 motif

Sorted Z-values of Dmc1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_-_86906937 3.72 ENSMUST00000031181.9
ENSMUST00000113333.1
UDP glucuronosyltransferase 2 family, polypeptide B34
chr12_-_84698769 2.30 ENSMUST00000095550.2
synapse differentiation inducing 1 like
chr19_-_10457447 2.28 ENSMUST00000171400.2
leucine rich repeat containing 10B
chr10_+_115817247 2.26 ENSMUST00000035563.7
ENSMUST00000080630.3
ENSMUST00000179196.1
tetraspanin 8
chr2_-_129699833 2.05 ENSMUST00000028883.5
prodynorphin
chr19_+_4081565 1.88 ENSMUST00000159593.1
calcium binding protein 2
chr9_-_45204083 1.72 ENSMUST00000034599.8
transmembrane protease, serine 4
chr2_-_62483637 1.52 ENSMUST00000136686.1
ENSMUST00000102733.3
glucagon
chr7_-_127890918 1.45 ENSMUST00000121394.1
protease, serine, 53
chr4_+_128058962 1.36 ENSMUST00000184063.1
CUB and Sushi multiple domains 2
chr6_-_112489808 1.33 ENSMUST00000053306.6
oxytocin receptor
chr4_+_104766308 1.30 ENSMUST00000031663.3
complement component 8, beta polypeptide
chr18_-_82406777 1.26 ENSMUST00000065224.6
galanin receptor 1
chr7_-_100656953 1.25 ENSMUST00000107046.1
ENSMUST00000107045.1
ENSMUST00000139708.1
pleckstrin homology domain containing, family B (evectins) member 1
chr4_+_104766334 1.22 ENSMUST00000065072.6
complement component 8, beta polypeptide
chr4_-_49549523 1.20 ENSMUST00000029987.9
aldolase B, fructose-bisphosphate
chr10_-_81291227 1.12 ENSMUST00000045744.6
tight junction protein 3
chrX_-_17319316 1.10 ENSMUST00000026014.7
EF-hand domain (C-terminal) containing 2
chr4_-_107307118 1.10 ENSMUST00000126291.1
ENSMUST00000106748.1
ENSMUST00000129138.1
ENSMUST00000082426.3
deiodinase, iodothyronine, type I
chr9_-_62510498 1.10 ENSMUST00000164246.2
coronin, actin binding protein, 2B
chr4_+_58943575 1.04 ENSMUST00000107554.1
zinc finger with KRAB and SCAN domains 16
chr1_-_79440039 1.04 ENSMUST00000049972.4
secretogranin II
chr6_+_107529717 0.98 ENSMUST00000049285.8
leucine rich repeat protein 1, neuronal
chr7_-_30861470 0.93 ENSMUST00000052700.3
free fatty acid receptor 1
chr6_-_5496296 0.91 ENSMUST00000019721.4
pyruvate dehydrogenase kinase, isoenzyme 4
chr10_-_60938123 0.90 ENSMUST00000036304.3
polymorphic derived intron containing
chr4_+_110397764 0.89 ENSMUST00000097920.2
ENSMUST00000080744.6
ATP/GTP binding protein-like 4
chr4_+_110397661 0.89 ENSMUST00000106589.2
ENSMUST00000106587.2
ENSMUST00000106591.1
ENSMUST00000106592.1
ATP/GTP binding protein-like 4
chr4_-_131672133 0.84 ENSMUST00000144212.1
predicted gene 12962
chr6_+_135198034 0.81 ENSMUST00000130612.1
RIKEN cDNA 8430419L09 gene
chr10_+_69212676 0.81 ENSMUST00000167384.1
Rho-related BTB domain containing 1
chr2_-_66634653 0.80 ENSMUST00000164384.2
ENSMUST00000169900.1
sodium channel, voltage-gated, type IX, alpha
chr15_+_33083110 0.79 ENSMUST00000042167.9
carboxypeptidase Q
chr14_-_29721835 0.78 ENSMUST00000022567.7
calcium channel, voltage-dependent, alpha2/delta subunit 3
chr6_+_71199827 0.75 ENSMUST00000067492.7
fatty acid binding protein 1, liver
chr15_-_32244632 0.74 ENSMUST00000181536.1
RIKEN cDNA 0610007N19
chr10_-_75797528 0.74 ENSMUST00000120177.1
glutathione S-transferase, theta 1
chr4_+_108879130 0.71 ENSMUST00000106651.2
RAB3B, member RAS oncogene family
chr4_-_137118135 0.70 ENSMUST00000154285.1
predicted gene 13001
chr8_+_70718534 0.69 ENSMUST00000179347.1
predicted gene 3336
chr1_+_87124946 0.67 ENSMUST00000044878.3
alkaline phosphatase 3, intestine, not Mn requiring
chr4_+_46039202 0.65 ENSMUST00000156200.1
tropomodulin 1
chr4_+_150087365 0.65 ENSMUST00000094451.3
G protein-coupled receptor 157
chr7_-_126649556 0.64 ENSMUST00000084587.1
RIKEN cDNA 2510046G10 gene
chr8_-_71701796 0.62 ENSMUST00000034260.7
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
chr6_+_34384218 0.61 ENSMUST00000038383.7
ENSMUST00000115051.1
aldo-keto reductase family 1, member B10 (aldose reductase)
chr8_-_4105764 0.61 ENSMUST00000138439.1
ENSMUST00000145007.1
CD209f antigen
chr13_-_92030897 0.60 ENSMUST00000149630.1
RAS protein-specific guanine nucleotide-releasing factor 2
chr16_-_44016387 0.60 ENSMUST00000036174.3
GRAM domain containing 1C
chrX_+_23693043 0.60 ENSMUST00000035766.6
ENSMUST00000101670.2
WD repeat domain 44
chr4_+_43267165 0.60 ENSMUST00000107942.2
ENSMUST00000102953.3
ATPase, class I, type 8B, member 5
chr18_+_37447641 0.59 ENSMUST00000052387.3
protocadherin beta 14
chr13_-_23914998 0.59 ENSMUST00000021769.8
ENSMUST00000110407.2
solute carrier family 17 (sodium phosphate), member 4
chr4_+_133553370 0.59 ENSMUST00000042706.2
nuclear receptor subfamily 0, group B, member 2
chr19_-_8929323 0.57 ENSMUST00000096242.3
rod outer segment membrane protein 1
chr18_-_22171392 0.57 ENSMUST00000025160.2
coiled coil domain containing 178
chr16_+_48872608 0.57 ENSMUST00000065666.4
resistin like gamma
chr5_-_6876523 0.57 ENSMUST00000164784.1
zinc finger protein 804B
chr1_+_174501796 0.56 ENSMUST00000030039.7
formin 2
chr15_+_89322969 0.54 ENSMUST00000066991.5
adrenomedullin 2
chr5_+_107437908 0.54 ENSMUST00000094541.2
BTB (POZ) domain containing 8
chr13_+_62129894 0.52 ENSMUST00000099449.3
zinc finger protein 80
chr9_-_105495475 0.51 ENSMUST00000176036.1
ATPase, Ca++-sequestering
chr17_+_70561739 0.49 ENSMUST00000097288.2
discs, large (Drosophila) homolog-associated protein 1
chr5_+_102481374 0.49 ENSMUST00000094559.2
ENSMUST00000073302.5
Rho GTPase activating protein 24
chr15_+_89076124 0.47 ENSMUST00000165690.1
TraB domain containing
chr5_+_102481546 0.47 ENSMUST00000112854.1
Rho GTPase activating protein 24
chr9_+_110476985 0.47 ENSMUST00000084948.4
ENSMUST00000061155.6
ENSMUST00000140686.1
ENSMUST00000084952.5
kinesin family member 9
chr4_-_83285141 0.47 ENSMUST00000150522.1
tetratricopeptide repeat domain 39B
chr3_+_106113229 0.47 ENSMUST00000079132.5
ENSMUST00000139086.1
chitinase, acidic
chr11_+_120348678 0.46 ENSMUST00000143813.1
RIKEN cDNA 0610009L18 gene
chr9_-_37657189 0.46 ENSMUST00000117654.1
transforming growth factor beta regulated gene 1
chr11_+_78322965 0.46 ENSMUST00000017534.8
aldolase C, fructose-bisphosphate
chr13_-_62371936 0.46 ENSMUST00000107989.3
predicted gene 3604
chr19_+_42247544 0.46 ENSMUST00000122375.1
golgi autoantigen, golgin subfamily a, 7B
chr9_-_21592805 0.45 ENSMUST00000034700.7
ENSMUST00000180365.1
ENSMUST00000078572.7
Yip1 domain family, member 2
chr1_+_24005505 0.44 ENSMUST00000181961.1
predicted gene, 26524
chr2_-_26360873 0.44 ENSMUST00000028294.6
caspase recruitment domain family, member 9
chr9_-_100571049 0.44 ENSMUST00000093792.2
solute carrier family 35, member G2
chr18_-_61536522 0.44 ENSMUST00000171629.1
Rho guanine nucleotide exchange factor (GEF) 37
chr14_+_30886476 0.43 ENSMUST00000006703.6
ENSMUST00000078490.5
ENSMUST00000120269.2
inter alpha-trypsin inhibitor, heavy chain 4
chr13_-_49215978 0.43 ENSMUST00000048946.6
RIKEN cDNA 1110007C09 gene
chr4_+_134396320 0.42 ENSMUST00000105869.2
platelet-activating factor acetylhydrolase 2
chr13_-_67755132 0.42 ENSMUST00000091520.6
zinc finger protein 85, related sequence 1
chr7_-_45615484 0.42 ENSMUST00000033099.4
fibroblast growth factor 21
chr19_-_57197556 0.42 ENSMUST00000099294.2
actin-binding LIM protein 1
chr10_-_89533550 0.42 ENSMUST00000105297.1
nuclear receptor subfamily 1, group H, member 4
chr4_-_147936713 0.42 ENSMUST00000105712.1
ENSMUST00000019199.7
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
chr18_+_37421418 0.41 ENSMUST00000053073.4
protocadherin beta 11
chr15_+_34453285 0.41 ENSMUST00000060894.7
cDNA sequence BC030476
chr4_-_41640322 0.41 ENSMUST00000127306.1
energy homeostasis associated
chrX_+_53607918 0.41 ENSMUST00000114827.1
CAAX box 1C
chr16_-_17132377 0.41 ENSMUST00000023453.7
stromal cell-derived factor 2-like 1
chr6_-_131316398 0.41 ENSMUST00000121078.1
serine/threonine/tyrosine kinase 1
chr9_-_104102550 0.40 ENSMUST00000050139.4
atypical chemokine receptor 4
chr18_+_37264998 0.39 ENSMUST00000052366.3
protocadherin beta 1
chr1_+_95313607 0.39 ENSMUST00000059975.6
family with sequence similarity 174, member A
chr1_+_88166004 0.39 ENSMUST00000097659.4
UDP glucuronosyltransferase 1 family, polypeptide A5
chr4_-_150198469 0.39 ENSMUST00000105683.2
carbonic anhydrase 6
chr3_-_63929376 0.39 ENSMUST00000061706.6
RIKEN cDNA E130311K13 gene
chr7_+_27486910 0.39 ENSMUST00000008528.7
SERTA domain containing 1
chr9_+_86743641 0.39 ENSMUST00000179574.1
protease, serine, 35
chrX_+_159697308 0.39 ENSMUST00000123433.1
SH3-domain kinase binding protein 1
chr13_-_67755192 0.39 ENSMUST00000144183.1
zinc finger protein 85, related sequence 1
chr2_+_83724397 0.38 ENSMUST00000028499.4
ENSMUST00000141725.1
ENSMUST00000111740.2
integrin alpha V
chr14_-_30626196 0.38 ENSMUST00000112210.3
ENSMUST00000112211.2
ENSMUST00000112208.1
protein kinase C, delta
chr12_-_84876479 0.38 ENSMUST00000163189.1
ENSMUST00000110254.2
ENSMUST00000002073.6
latent transforming growth factor beta binding protein 2
chr11_-_69880971 0.38 ENSMUST00000050555.3
potassium channel tetramerisation domain containing 11
chr3_+_135825788 0.38 ENSMUST00000167390.1
solute carrier family 39 (metal ion transporter), member 8
chr5_-_92348871 0.38 ENSMUST00000038816.6
ENSMUST00000118006.1
chemokine (C-X-C motif) ligand 10
chrX_+_103630575 0.38 ENSMUST00000033692.7
zinc finger, CCHC domain containing 13
chr6_+_41538218 0.38 ENSMUST00000103291.1
T cell receptor beta, constant region 1
chr16_-_48771956 0.37 ENSMUST00000170861.1
T cell receptor associated transmembrane adaptor 1
chr6_-_69400097 0.37 ENSMUST00000177795.1
immunoglobulin kappa variable 4-62
chr1_+_109983737 0.37 ENSMUST00000172005.1
cadherin 7, type 2
chr11_+_48837465 0.37 ENSMUST00000046903.5
tripartite motif-containing 7
chr18_+_37484955 0.37 ENSMUST00000053856.4
protocadherin beta 17
chr9_+_86743616 0.36 ENSMUST00000036426.6
protease, serine, 35
chrX_+_140907602 0.36 ENSMUST00000033806.4
V-set and immunoglobulin domain containing 1
chr5_+_30013141 0.36 ENSMUST00000026845.7
interleukin 6
chr3_-_121815212 0.36 ENSMUST00000029770.5
ATP-binding cassette, sub-family D (ALD), member 3
chr16_-_43979050 0.35 ENSMUST00000165648.1
ENSMUST00000036321.7
zinc finger, DHHC domain containing 23
chrX_-_73458990 0.35 ENSMUST00000033737.8
ENSMUST00000077243.4
HAUS augmin-like complex, subunit 7
chr9_-_75441652 0.35 ENSMUST00000181896.1
RIKEN cDNA A130057D12 gene
chr19_+_53529100 0.35 ENSMUST00000038287.6
dual specificity phosphatase 5
chr8_-_9976294 0.34 ENSMUST00000095476.4
ligase IV, DNA, ATP-dependent
chr12_-_26456423 0.34 ENSMUST00000020970.7
radical S-adenosyl methionine domain containing 2
chr4_+_95967205 0.34 ENSMUST00000030306.7
hook homolog 1 (Drosophila)
chr2_-_3422576 0.34 ENSMUST00000144584.1
meiosis expressed gene 1
chr11_-_96916448 0.34 ENSMUST00000103152.4
CDK5 regulatory subunit associated protein 3
chr8_+_104733997 0.34 ENSMUST00000034346.8
ENSMUST00000164182.2
carboxylesterase 2A
chr2_-_104742802 0.34 ENSMUST00000028595.7
DEP domain containing 7
chr14_-_121915774 0.34 ENSMUST00000055475.7
G protein-coupled receptor 18
chr16_+_33062512 0.34 ENSMUST00000023497.2
leishmanolysin-like (metallopeptidase M8 family)
chr17_-_66594592 0.33 ENSMUST00000024914.2
thymocyte selection associated family member 3
chr1_+_164062070 0.33 ENSMUST00000097491.3
ENSMUST00000027871.7
selectin, lymphocyte
chr14_+_30886521 0.33 ENSMUST00000168782.1
inter alpha-trypsin inhibitor, heavy chain 4
chr3_+_135825648 0.32 ENSMUST00000180196.1
solute carrier family 39 (metal ion transporter), member 8
chr14_-_55788810 0.32 ENSMUST00000022830.6
ENSMUST00000168716.1
ENSMUST00000178399.1
receptor-interacting serine-threonine kinase 3
chr4_-_132144486 0.32 ENSMUST00000056336.1
opioid receptor, delta 1
chr10_-_117282262 0.31 ENSMUST00000092163.7
lysozyme 2
chr15_-_39112642 0.31 ENSMUST00000022908.8
solute carrier family 25, member 32
chr11_+_5569679 0.31 ENSMUST00000109856.1
ENSMUST00000109855.1
ENSMUST00000118112.2
ankyrin repeat domain 36
chr10_+_116986314 0.31 ENSMUST00000020378.4
bestrophin 3
chr15_+_102270540 0.30 ENSMUST00000181801.1
predicted gene 9918
chr8_-_45410539 0.30 ENSMUST00000034056.4
ENSMUST00000167106.1
toll-like receptor 3
chr4_+_126609818 0.30 ENSMUST00000097886.3
ENSMUST00000164362.1
RIKEN cDNA 5730409E04Rik gene
chrX_-_36864238 0.30 ENSMUST00000115249.3
ENSMUST00000115248.3
RIKEN cDNA C330007P06 gene
chr4_+_98546710 0.30 ENSMUST00000102792.3
InaD-like (Drosophila)
chr6_-_142278836 0.30 ENSMUST00000111825.3
solute carrier organic anion transporter family, member 1a5
chr14_+_61309753 0.30 ENSMUST00000055159.7
ADP-ribosylation factor-like 11
chr8_+_4134733 0.30 ENSMUST00000130372.1
CD209g antigen
chr4_-_134095078 0.30 ENSMUST00000000696.6
CD52 antigen
chr11_+_49280150 0.29 ENSMUST00000078932.1
olfactory receptor 1393
chr5_+_25516061 0.29 ENSMUST00000045016.7
chaperonin containing TCP1, subunit 8 (theta)-like 1
chr7_+_126649297 0.29 ENSMUST00000032956.8
coiled-coil domain containing 101
chr15_+_102102926 0.29 ENSMUST00000169627.1
ENSMUST00000046144.9
tensin like C1 domain-containing phosphatase
chr10_+_75212065 0.29 ENSMUST00000105421.2
sperm antigen with calponin homology and coiled-coil domains 1-like
chr7_+_43634718 0.29 ENSMUST00000032663.8
carcinoembryonic antigen-related cell adhesion molecule 18
chr11_+_116531744 0.28 ENSMUST00000106387.2
ENSMUST00000100201.3
sphingosine kinase 1
chrX_+_134756563 0.28 ENSMUST00000081834.3
ENSMUST00000086880.4
ENSMUST00000086884.4
armadillo repeat containing, X-linked 3
chr6_-_82774448 0.28 ENSMUST00000000642.4
hexokinase 2
chr3_-_59180085 0.28 ENSMUST00000056898.4
G protein-coupled receptor 87
chr7_-_133709051 0.28 ENSMUST00000124759.1
ENSMUST00000106144.1
uroporphyrinogen III synthase
chr18_+_21072329 0.28 ENSMUST00000082235.4
meprin 1 beta
chr10_-_105841323 0.27 ENSMUST00000046638.9
methyltransferase like 25
chr9_+_92275602 0.27 ENSMUST00000034932.7
ENSMUST00000180154.1
phospholipid scramblase 2
chr1_-_193264006 0.27 ENSMUST00000161737.1
hydroxysteroid 11-beta dehydrogenase 1
chr16_-_59027927 0.27 ENSMUST00000062380.2
olfactory receptor 186
chr13_+_21754067 0.27 ENSMUST00000091709.2
histone cluster 1, H2bn
chr1_-_82291370 0.27 ENSMUST00000069799.2
insulin receptor substrate 1
chr9_+_92275746 0.27 ENSMUST00000126911.1
phospholipid scramblase 2
chr11_+_116532441 0.27 ENSMUST00000106386.1
ENSMUST00000145737.1
ENSMUST00000155102.1
ENSMUST00000063446.6
sphingosine kinase 1
chr5_-_123140135 0.27 ENSMUST00000160099.1
expressed sequence AI480526
chr1_+_88095054 0.27 ENSMUST00000150634.1
ENSMUST00000058237.7
UDP glucuronosyltransferase 1 family, polypeptide A7C
chr19_-_46672883 0.27 ENSMUST00000026012.7
cytochrome P450, family 17, subfamily a, polypeptide 1
chr5_+_149265035 0.26 ENSMUST00000130144.1
ENSMUST00000071130.3
arachidonate 5-lipoxygenase activating protein
chr1_-_171281181 0.26 ENSMUST00000073120.4
protoporphyrinogen oxidase
chr7_-_12998172 0.26 ENSMUST00000120903.1
solute carrier family 27 (fatty acid transporter), member 5
chr7_-_102724510 0.26 ENSMUST00000084816.3
olfactory receptor 559
chr10_-_5069044 0.26 ENSMUST00000095899.3
spectrin repeat containing, nuclear envelope 1
chr2_+_28506095 0.26 ENSMUST00000074761.4
predicted gene 10134
chr5_-_113993873 0.26 ENSMUST00000159592.1
slingshot homolog 1 (Drosophila)
chr8_+_83290342 0.26 ENSMUST00000034146.3
uncoupling protein 1 (mitochondrial, proton carrier)
chr16_-_96443595 0.26 ENSMUST00000113773.1
ENSMUST00000000161.7
integrin beta 2-like
chr14_+_62663665 0.26 ENSMUST00000171692.1
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 3
chr10_-_20312239 0.26 ENSMUST00000092680.2
RIKEN cDNA 4933406P04 gene
chr1_-_171535284 0.26 ENSMUST00000043094.6
intelectin 1 (galactofuranose binding)
chr2_-_106003549 0.26 ENSMUST00000102555.4
DnaJ (Hsp40) homolog, subfamily C, member 24
chr8_+_121950492 0.26 ENSMUST00000093078.6
ENSMUST00000170857.1
ENSMUST00000026354.8
ENSMUST00000174753.1
ENSMUST00000172511.1
BTG3 associated nuclear protein
chr3_+_31902507 0.25 ENSMUST00000119310.1
potassium large conductance calcium-activated channel, subfamily M, beta member 2
chr11_+_58786139 0.25 ENSMUST00000076393.3
olfactory receptor 314
chr9_-_26806384 0.25 ENSMUST00000162702.1
ENSMUST00000040398.7
ENSMUST00000066560.6
galactosidase, beta 1-like 2
chr18_-_9450097 0.25 ENSMUST00000053917.4
cyclin Y
chr7_-_119459266 0.25 ENSMUST00000033255.5
glycoprotein 2 (zymogen granule membrane)
chrX_-_49288195 0.25 ENSMUST00000114914.1
ecto-NOX disulfide-thiol exchanger 2
chr11_-_69761963 0.25 ENSMUST00000102586.3
solute carrier family 35, member G3
chr18_-_35662180 0.25 ENSMUST00000025209.4
ENSMUST00000096573.2
spermatogenesis associated 24
chr2_+_113441064 0.25 ENSMUST00000081349.6
formin 1
chr2_+_120567687 0.25 ENSMUST00000028743.3
ENSMUST00000116437.1
ENSMUST00000153580.1
ENSMUST00000142278.1
synaptosomal-associated protein 23

Network of associatons between targets according to the STRING database.

First level regulatory network of Dmc1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.8 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.4 1.3 GO:0051464 positive regulation of cortisol secretion(GO:0051464)
0.3 1.3 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.3 1.2 GO:0061625 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624) glycolytic process through fructose-1-phosphate(GO:0061625)
0.2 0.7 GO:0042197 dichloromethane metabolic process(GO:0018900) chlorinated hydrocarbon metabolic process(GO:0042196) halogenated hydrocarbon metabolic process(GO:0042197)
0.2 0.9 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.2 1.5 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.2 0.2 GO:0034769 basement membrane disassembly(GO:0034769)
0.2 0.6 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344) formin-nucleated actin cable assembly(GO:0070649)
0.2 0.7 GO:0051582 positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944) regulation of vesicle size(GO:0097494)
0.2 2.5 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.2 0.6 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.1 0.6 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
0.1 0.4 GO:0034971 histone H3-R17 methylation(GO:0034971)
0.1 0.6 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.1 0.5 GO:0055071 cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) manganese ion homeostasis(GO:0055071)
0.1 0.4 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.1 0.2 GO:0032849 positive regulation of cellular pH reduction(GO:0032849)
0.1 0.5 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.1 0.4 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.1 0.4 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.1 0.3 GO:0034165 positive regulation of toll-like receptor 9 signaling pathway(GO:0034165)
0.1 0.3 GO:0002304 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.1 1.0 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.1 0.4 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.1 0.3 GO:0098976 excitatory chemical synaptic transmission(GO:0098976) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.1 0.4 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.1 0.4 GO:1901740 negative regulation of myoblast fusion(GO:1901740)
0.1 0.5 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.1 0.3 GO:0006713 glucocorticoid catabolic process(GO:0006713)
0.1 0.3 GO:0046271 coumarin metabolic process(GO:0009804) phenylpropanoid catabolic process(GO:0046271)
0.1 0.2 GO:0043387 mycotoxin metabolic process(GO:0043385) mycotoxin catabolic process(GO:0043387) aflatoxin metabolic process(GO:0046222) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound metabolic process(GO:1901376) organic heteropentacyclic compound catabolic process(GO:1901377)
0.1 0.2 GO:0071338 positive regulation of hair follicle cell proliferation(GO:0071338)
0.1 0.3 GO:2000449 regulation of CD8-positive, alpha-beta T cell extravasation(GO:2000449)
0.1 0.6 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 0.3 GO:0045356 positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.1 0.4 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.1 0.2 GO:0038027 apolipoprotein A-I-mediated signaling pathway(GO:0038027)
0.1 0.8 GO:0006590 thyroid hormone generation(GO:0006590)
0.1 0.3 GO:0006780 uroporphyrinogen III biosynthetic process(GO:0006780)
0.1 1.0 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.1 0.2 GO:0006011 UDP-glucose metabolic process(GO:0006011)
0.1 0.3 GO:0009624 response to nematode(GO:0009624)
0.1 0.3 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.1 1.0 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.1 0.4 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.1 0.2 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.1 0.2 GO:0003127 detection of nodal flow(GO:0003127) detection of endogenous stimulus(GO:0009726)
0.1 0.2 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 0.2 GO:1901475 pyruvate transmembrane transport(GO:1901475)
0.1 0.2 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.1 0.3 GO:0097680 double-strand break repair via classical nonhomologous end joining(GO:0097680)
0.1 0.3 GO:1901526 negative regulation of mitochondrial membrane permeability(GO:0035795) positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.1 0.2 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.1 0.2 GO:0071799 response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799)
0.1 0.7 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.1 0.3 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.1 0.4 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.1 0.2 GO:0052055 response to yeast(GO:0001878) modulation by symbiont of host molecular function(GO:0052055) modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
0.1 0.4 GO:0019348 dolichol metabolic process(GO:0019348)
0.1 0.2 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.1 0.2 GO:0060775 mediolateral intercalation(GO:0060031) planar cell polarity pathway involved in gastrula mediolateral intercalation(GO:0060775)
0.1 0.3 GO:0002386 immune response in mucosal-associated lymphoid tissue(GO:0002386)
0.0 0.6 GO:0060019 radial glial cell differentiation(GO:0060019)
0.0 0.1 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.0 0.2 GO:0097167 circadian regulation of translation(GO:0097167)
0.0 0.2 GO:0038094 Fc-gamma receptor signaling pathway(GO:0038094)
0.0 0.2 GO:0070829 heterochromatin maintenance(GO:0070829)
0.0 0.2 GO:0015820 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.0 0.2 GO:0007060 male meiosis chromosome segregation(GO:0007060)
0.0 0.2 GO:0060455 negative regulation of gastric acid secretion(GO:0060455)
0.0 0.2 GO:1901594 detection of temperature stimulus involved in thermoception(GO:0050960) response to capsazepine(GO:1901594)
0.0 2.3 GO:1900047 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.0 0.3 GO:0090292 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.2 GO:0009115 xanthine catabolic process(GO:0009115)
0.0 0.1 GO:1902093 thymocyte migration(GO:0072679) positive regulation of sperm motility(GO:1902093)
0.0 0.4 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)
0.0 0.2 GO:1902167 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902167)
0.0 0.1 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.0 0.5 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.2 GO:0072092 ureteric bud invasion(GO:0072092)
0.0 0.2 GO:0010166 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.0 0.2 GO:0048050 post-embryonic eye morphogenesis(GO:0048050) post-embryonic camera-type eye morphogenesis(GO:0048597)
0.0 0.2 GO:1904075 regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.0 0.1 GO:0042488 positive regulation of odontogenesis of dentin-containing tooth(GO:0042488) regulation of enamel mineralization(GO:0070173)
0.0 0.2 GO:0038145 macrophage colony-stimulating factor signaling pathway(GO:0038145)
0.0 0.6 GO:0052695 cellular glucuronidation(GO:0052695)
0.0 0.2 GO:0010958 regulation of amino acid import(GO:0010958)
0.0 0.5 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.5 GO:0070842 aggresome assembly(GO:0070842)
0.0 0.3 GO:0071569 protein ufmylation(GO:0071569)
0.0 0.2 GO:0000103 sulfate assimilation(GO:0000103)
0.0 0.2 GO:2000258 negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.0 0.2 GO:1903278 positive regulation of sodium ion export(GO:1903275) positive regulation of sodium ion export from cell(GO:1903278)
0.0 0.5 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.1 GO:1901026 ripoptosome assembly(GO:0097343) ripoptosome assembly involved in necroptotic process(GO:1901026)
0.0 2.1 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.1 GO:1900247 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.0 0.1 GO:0070543 response to linoleic acid(GO:0070543)
0.0 0.2 GO:0033602 negative regulation of dopamine secretion(GO:0033602) negative regulation of ATP biosynthetic process(GO:2001170)
0.0 0.2 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.0 0.4 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 0.1 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.0 0.1 GO:0046010 positive regulation of circadian sleep/wake cycle, non-REM sleep(GO:0046010)
0.0 0.3 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 0.1 GO:0044830 modulation by host of viral RNA genome replication(GO:0044830)
0.0 0.3 GO:0034374 low-density lipoprotein particle remodeling(GO:0034374)
0.0 0.1 GO:0031622 positive regulation of fever generation(GO:0031622)
0.0 0.4 GO:0042226 interleukin-6 biosynthetic process(GO:0042226) regulation of interleukin-6 biosynthetic process(GO:0045408)
0.0 0.1 GO:1902938 regulation of intracellular calcium activated chloride channel activity(GO:1902938)
0.0 0.2 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.0 0.4 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.1 GO:0032379 positive regulation of intracellular lipid transport(GO:0032379) positive regulation of intracellular sterol transport(GO:0032382) positive regulation of intracellular cholesterol transport(GO:0032385) lipid hydroperoxide transport(GO:1901373)
0.0 0.7 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.0 0.3 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.1 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.2 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.0 0.2 GO:0015747 urate transport(GO:0015747)
0.0 0.2 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.3 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.1 GO:1903756 regulation of postsynaptic density protein 95 clustering(GO:1902897) regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.0 0.2 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.2 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.2 GO:0043415 vitamin A metabolic process(GO:0006776) positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.0 0.3 GO:0060837 blood vessel endothelial cell differentiation(GO:0060837)
0.0 0.4 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 0.8 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.2 GO:0021554 optic nerve development(GO:0021554)
0.0 0.1 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 0.3 GO:0042448 progesterone metabolic process(GO:0042448)
0.0 1.1 GO:0070542 response to fatty acid(GO:0070542)
0.0 0.1 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.0 0.6 GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.0 0.1 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.0 0.2 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.0 0.1 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.0 1.1 GO:0042446 hormone biosynthetic process(GO:0042446)
0.0 0.0 GO:0072162 metanephric mesenchymal cell differentiation(GO:0072162)
0.0 0.2 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.0 0.1 GO:0019659 fermentation(GO:0006113) glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661)
0.0 0.4 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.3 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0 0.5 GO:0071801 regulation of podosome assembly(GO:0071801)
0.0 0.2 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.1 GO:0045014 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.0 0.1 GO:0035425 autocrine signaling(GO:0035425)
0.0 0.1 GO:0018307 tRNA wobble position uridine thiolation(GO:0002143) enzyme active site formation(GO:0018307)
0.0 0.1 GO:0045112 tendon development(GO:0035989) integrin biosynthetic process(GO:0045112)
0.0 0.4 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.0 0.5 GO:0048266 behavioral response to pain(GO:0048266)
0.0 0.2 GO:0032495 response to muramyl dipeptide(GO:0032495)
0.0 0.0 GO:0060722 spongiotrophoblast cell proliferation(GO:0060720) cell proliferation involved in embryonic placenta development(GO:0060722)
0.0 0.2 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.1 GO:2000484 positive regulation of interleukin-8 secretion(GO:2000484)
0.0 0.2 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.0 0.4 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.2 GO:0030497 fatty acid elongation(GO:0030497)
0.0 0.2 GO:2000582 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.3 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.7 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.1 GO:0031133 regulation of axon diameter(GO:0031133)
0.0 0.1 GO:0002481 antigen processing and presentation of exogenous peptide antigen via MHC class Ib(GO:0002477) antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent(GO:0002481) regulation of iron ion transport(GO:0034756) regulation of iron ion transmembrane transport(GO:0034759) positive regulation of receptor binding(GO:1900122)
0.0 0.1 GO:0035330 regulation of hippo signaling(GO:0035330)
0.0 0.0 GO:0035754 B cell chemotaxis(GO:0035754)
0.0 0.2 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0 1.8 GO:0007416 synapse assembly(GO:0007416)
0.0 0.1 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0 0.2 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.0 0.2 GO:0042407 cristae formation(GO:0042407)
0.0 0.1 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.0 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.0 0.4 GO:0043304 regulation of mast cell activation involved in immune response(GO:0033006) regulation of mast cell degranulation(GO:0043304)
0.0 0.3 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.0 0.2 GO:0036010 protein localization to endosome(GO:0036010)
0.0 0.1 GO:0071294 cellular response to zinc ion(GO:0071294)
0.0 0.1 GO:0001682 tRNA 5'-leader removal(GO:0001682)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.2 GO:0097425 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.3 2.5 GO:0005579 membrane attack complex(GO:0005579)
0.1 0.4 GO:0034684 integrin alphav-beta5 complex(GO:0034684) integrin alphav-beta6 complex(GO:0034685)
0.1 0.3 GO:0005899 insulin receptor complex(GO:0005899)
0.1 0.4 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.1 0.4 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 0.3 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) DNA ligase IV complex(GO:0032807)
0.1 1.0 GO:0031045 dense core granule(GO:0031045)
0.1 0.8 GO:0045179 apical cortex(GO:0045179)
0.1 0.2 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.1 0.3 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.1 0.3 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.1 GO:0032783 ELL-EAF complex(GO:0032783)
0.0 0.3 GO:0070695 FHF complex(GO:0070695)
0.0 0.2 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.8 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.4 GO:0070652 HAUS complex(GO:0070652)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.6 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.2 GO:0005745 m-AAA complex(GO:0005745)
0.0 0.3 GO:0097342 ripoptosome(GO:0097342)
0.0 0.4 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.4 GO:0031983 vesicle lumen(GO:0031983)
0.0 0.5 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.0 0.2 GO:0000322 storage vacuole(GO:0000322)
0.0 0.2 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.0 0.2 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0 0.2 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.4 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.1 GO:0097443 sorting endosome(GO:0097443)
0.0 0.4 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.2 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0 0.2 GO:0001940 male pronucleus(GO:0001940)
0.0 0.3 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.1 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.0 0.3 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.1 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.3 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.1 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.5 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.4 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.1 GO:0031021 interphase microtubule organizing center(GO:0031021)
0.0 0.5 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.2 GO:0042599 lamellar body(GO:0042599)
0.0 0.8 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 1.2 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.6 GO:0060170 ciliary membrane(GO:0060170)
0.0 0.1 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.2 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.4 GO:0042588 zymogen granule(GO:0042588)
0.0 1.7 GO:0005814 centriole(GO:0005814)
0.0 0.1 GO:0097542 ciliary tip(GO:0097542)
0.0 0.0 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 0.1 GO:0098642 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.0 0.5 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.5 GO:0002102 podosome(GO:0002102)
0.0 0.4 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.1 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.4 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.5 GO:0032590 dendrite membrane(GO:0032590)
0.0 0.4 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.0 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 0.1 GO:0016593 Cdc73/Paf1 complex(GO:0016593)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.3 2.0 GO:0001515 opioid peptide activity(GO:0001515)
0.3 1.3 GO:0004966 galanin receptor activity(GO:0004966)
0.2 0.7 GO:0019120 hydrolase activity, acting on acid halide bonds(GO:0016824) hydrolase activity, acting on acid halide bonds, in C-halide compounds(GO:0019120) alkylhalidase activity(GO:0047651)
0.2 1.7 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.2 0.9 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.2 0.6 GO:0047223 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532) beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity(GO:0047223)
0.2 0.6 GO:0070401 NADP+ binding(GO:0070401)
0.2 0.8 GO:0070573 metallodipeptidase activity(GO:0070573)
0.2 1.1 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.1 1.0 GO:0005000 vasopressin receptor activity(GO:0005000)
0.1 4.8 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 0.5 GO:0015410 manganese-transporting ATPase activity(GO:0015410)
0.1 0.8 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 0.4 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.1 0.4 GO:0070976 TIR domain binding(GO:0070976)
0.1 0.7 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.1 0.3 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.1 0.4 GO:0038181 bile acid receptor activity(GO:0038181)
0.1 0.5 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.1 0.4 GO:0019960 C-X3-C chemokine binding(GO:0019960)
0.1 0.2 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.1 0.4 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 0.2 GO:0034188 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.1 0.2 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.1 0.2 GO:0004771 sterol esterase activity(GO:0004771) retinyl-palmitate esterase activity(GO:0050253)
0.1 0.3 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.1 0.3 GO:0004985 opioid receptor activity(GO:0004985)
0.1 0.2 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.1 0.9 GO:0045125 bioactive lipid receptor activity(GO:0045125)
0.1 1.8 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 0.2 GO:0016501 prostacyclin receptor activity(GO:0016501)
0.1 0.2 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.1 0.7 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.1 0.5 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.1 0.3 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 0.2 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.0 0.1 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.0 0.2 GO:0042806 fucose binding(GO:0042806)
0.0 0.2 GO:0008390 testosterone 16-alpha-hydroxylase activity(GO:0008390)
0.0 0.1 GO:0052870 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871)
0.0 0.4 GO:0015245 fatty acid transporter activity(GO:0015245)
0.0 0.3 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.0 0.4 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 0.2 GO:0004031 aldehyde oxidase activity(GO:0004031) xanthine dehydrogenase activity(GO:0004854) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623) oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor(GO:0016726)
0.0 0.3 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.0 0.8 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.2 GO:0019863 IgE binding(GO:0019863)
0.0 0.6 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.3 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.1 GO:0004945 angiotensin type II receptor activity(GO:0004945)
0.0 1.9 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.2 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.0 0.2 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 1.0 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.7 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.0 0.8 GO:0031402 sodium ion binding(GO:0031402)
0.0 0.8 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.6 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.3 GO:0019158 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 3.3 GO:0005179 hormone activity(GO:0005179)
0.0 0.4 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.3 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.9 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.1 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.0 0.2 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.2 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.1 GO:0047936 glucose 1-dehydrogenase [NAD(P)] activity(GO:0047936)
0.0 0.1 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.0 0.2 GO:0097603 temperature-gated ion channel activity(GO:0097603)
0.0 0.1 GO:0042284 sphingolipid delta-4 desaturase activity(GO:0042284)
0.0 0.1 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.0 0.3 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.8 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.7 GO:0031489 myosin V binding(GO:0031489)
0.0 0.1 GO:0019002 GMP binding(GO:0019002)
0.0 0.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.2 GO:0051022 Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0 0.1 GO:0047522 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.0 0.1 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.0 0.2 GO:0000293 ferric-chelate reductase activity(GO:0000293) cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.2 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.2 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.1 GO:1990269 RNA polymerase II C-terminal domain phosphoserine binding(GO:1990269)
0.0 0.1 GO:0070538 oleic acid binding(GO:0070538)
0.0 0.2 GO:0035473 lipase binding(GO:0035473)
0.0 0.1 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.2 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.4 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
0.0 0.2 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.3 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0 0.4 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.7 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.3 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.6 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.2 GO:0043262 adenosine-diphosphatase activity(GO:0043262)
0.0 0.5 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.5 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 0.3 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.2 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 0.1 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 1.2 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.3 GO:0051861 glycolipid binding(GO:0051861)
0.0 0.2 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 0.1 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.0 0.1 GO:1990380 Lys63-specific deubiquitinase activity(GO:0061578) Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.8 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.2 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.0 0.4 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.3 GO:0005521 lamin binding(GO:0005521)
0.0 0.3 GO:0008517 folic acid transporter activity(GO:0008517)
0.0 0.3 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.1 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.0 0.1 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.1 GO:0097642 calcitonin family receptor activity(GO:0097642)
0.0 0.0 GO:0004998 transferrin receptor activity(GO:0004998)
0.0 2.0 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.0 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.1 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.0 0.1 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.5 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.1 GO:0030171 voltage-gated proton channel activity(GO:0030171)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.2 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 0.2 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.6 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.6 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.3 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 1.3 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.4 ST STAT3 PATHWAY STAT3 Pathway
0.0 0.3 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 0.6 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.2 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.6 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.3 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.2 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 REACTOME KINESINS Genes involved in Kinesins
0.1 2.5 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.1 0.3 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 0.5 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 0.9 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 1.9 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.1 0.3 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 2.0 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.0 0.7 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 1.1 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 1.7 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.7 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.4 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.4 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.6 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.1 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.1 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.4 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.6 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.5 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.2 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.6 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.4 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.6 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 3.0 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.3 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.0 0.8 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.8 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.2 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.4 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.2 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.2 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.3 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.3 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.4 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.4 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.6 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.2 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.4 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.5 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.1 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 0.1 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.3 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.5 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.4 REACTOME CELL CELL JUNCTION ORGANIZATION Genes involved in Cell-cell junction organization
0.0 0.4 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 2.1 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases