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12D miR HR13_24

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Results for Nfe2_Bach1_Mafk

Z-value: 0.64

Motif logo

Transcription factors associated with Nfe2_Bach1_Mafk

Gene Symbol Gene ID Gene Info
ENSMUSG00000058794.6 nuclear factor, erythroid derived 2
ENSMUSG00000025612.5 BTB and CNC homology 1, basic leucine zipper transcription factor 1
ENSMUSG00000018143.4 v-maf musculoaponeurotic fibrosarcoma oncogene family, protein K (avian)

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Bach1mm10_v2_chr16_+_87698904_876989590.721.3e-02Click!
Mafkmm10_v2_chr5_+_139791513_1397915390.691.9e-02Click!
Nfe2mm10_v2_chr15_-_103252810_1032528290.682.0e-02Click!

Activity profile of Nfe2_Bach1_Mafk motif

Sorted Z-values of Nfe2_Bach1_Mafk motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_33907721 2.06 ENSMUST00000115161.1
ENSMUST00000062289.8
BEN domain containing 6
chr10_+_4611971 1.08 ENSMUST00000105590.1
ENSMUST00000067086.7
estrogen receptor 1 (alpha)
chrX_+_164269371 0.94 ENSMUST00000145412.1
ENSMUST00000033749.7
pirin
chr9_+_7272514 0.92 ENSMUST00000015394.8
matrix metallopeptidase 13
chr2_+_11705437 0.81 ENSMUST00000148748.1
interleukin 15 receptor, alpha chain
chr2_+_11705459 0.79 ENSMUST00000126394.1
interleukin 15 receptor, alpha chain
chr2_+_11705712 0.75 ENSMUST00000138856.1
ENSMUST00000078834.5
ENSMUST00000114834.3
ENSMUST00000114833.3
ENSMUST00000114831.2
ENSMUST00000114832.2
interleukin 15 receptor, alpha chain
chr7_+_127800604 0.74 ENSMUST00000046863.5
ENSMUST00000106272.1
ENSMUST00000139068.1
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
chr2_-_42653598 0.70 ENSMUST00000052550.6
low density lipoprotein-related protein 1B (deleted in tumors)
chr9_+_32224457 0.70 ENSMUST00000183121.1
Rho GTPase activating protein 32
chr16_-_18811972 0.69 ENSMUST00000000028.7
ENSMUST00000115585.1
cell division cycle 45
chr2_+_11705287 0.65 ENSMUST00000135341.1
ENSMUST00000138349.1
ENSMUST00000123600.2
interleukin 15 receptor, alpha chain
chr2_+_11705355 0.61 ENSMUST00000128156.2
interleukin 15 receptor, alpha chain
chr6_+_129397478 0.60 ENSMUST00000112081.2
ENSMUST00000112079.2
C-type lectin domain family 1, member b
chr6_+_129397297 0.51 ENSMUST00000032262.7
C-type lectin domain family 1, member b
chr12_+_70974621 0.51 ENSMUST00000160027.1
ENSMUST00000160864.1
proteasome (prosome, macropain) subunit, alpha type 3
chrX_+_73675500 0.48 ENSMUST00000171398.1
solute carrier family 6 (neurotransmitter transporter, creatine), member 8
chr7_+_126766397 0.48 ENSMUST00000032944.7
glycerophosphodiester phosphodiesterase domain containing 3
chr2_-_32353247 0.46 ENSMUST00000078352.5
ENSMUST00000113352.2
ENSMUST00000113365.1
dynamin 1
chr7_+_127800844 0.46 ENSMUST00000106271.1
ENSMUST00000138432.1
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
chr11_+_78178651 0.45 ENSMUST00000092880.7
ENSMUST00000127587.1
ENSMUST00000108338.1
TLC domain containing 1
chr9_-_42461414 0.44 ENSMUST00000066179.7
tubulin folding cofactor E-like
chr17_-_45573253 0.42 ENSMUST00000165127.1
ENSMUST00000166469.1
ENSMUST00000024739.7
heat shock protein 90 alpha (cytosolic), class B member 1
chr9_+_32224246 0.41 ENSMUST00000168954.2
Rho GTPase activating protein 32
chr12_+_80518990 0.39 ENSMUST00000021558.6
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 16
chr17_+_35841668 0.37 ENSMUST00000174124.1
mediator of DNA damage checkpoint 1
chr18_+_61045139 0.36 ENSMUST00000025522.4
ENSMUST00000115274.1
platelet derived growth factor receptor, beta polypeptide
chr12_-_108275409 0.36 ENSMUST00000136175.1
coiled-coil domain containing 85C
chr8_-_107588392 0.35 ENSMUST00000044106.4
proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
chrX_-_134583114 0.35 ENSMUST00000113213.1
ENSMUST00000033617.6
Bruton agammaglobulinemia tyrosine kinase
chr7_-_30419802 0.34 ENSMUST00000075062.3
hematopoietic cell signal transducer
chr10_+_128933782 0.34 ENSMUST00000099112.2
integrin alpha 7
chr1_+_174172738 0.34 ENSMUST00000027817.7
spectrin alpha, erythrocytic 1
chr7_-_34230281 0.33 ENSMUST00000038027.4
glucose phosphate isomerase 1
chr9_+_64117147 0.33 ENSMUST00000034969.7
lactase-like
chr15_+_84669565 0.33 ENSMUST00000171460.1
proline rich 5 (renal)
chr3_+_122245557 0.33 ENSMUST00000029769.7
glutamate-cysteine ligase, modifier subunit
chr5_-_124187150 0.32 ENSMUST00000161938.1
phosphatidylinositol transfer protein, membrane-associated 2
chrX_+_93675088 0.32 ENSMUST00000045898.3
phosphate cytidylyltransferase 1, choline, beta isoform
chr17_-_45572495 0.32 ENSMUST00000130406.1
heat shock protein 90 alpha (cytosolic), class B member 1
chr13_-_14613017 0.31 ENSMUST00000015816.3
mitochondrial ribosomal protein L32
chr6_-_16898441 0.31 ENSMUST00000031533.7
transcription factor EC
chr11_+_76945719 0.31 ENSMUST00000125145.1
bleomycin hydrolase
chr2_+_167777467 0.31 ENSMUST00000139927.1
ENSMUST00000127441.1
predicted gene 14321
chr11_+_78178105 0.31 ENSMUST00000147819.1
TLC domain containing 1
chr6_+_5725639 0.30 ENSMUST00000115556.1
ENSMUST00000115555.1
ENSMUST00000115559.3
dynein cytoplasmic 1 intermediate chain 1
chr11_-_120630516 0.30 ENSMUST00000106181.1
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian)
chr4_+_116685859 0.30 ENSMUST00000129315.1
ENSMUST00000106470.1
peroxiredoxin 1
chrX_-_97377190 0.29 ENSMUST00000037353.3
ectodysplasin A2 receptor
chr12_-_84400929 0.29 ENSMUST00000122194.1
ectonucleoside triphosphate diphosphohydrolase 5
chr12_-_84400851 0.29 ENSMUST00000117286.1
ectonucleoside triphosphate diphosphohydrolase 5
chr7_+_120917744 0.28 ENSMUST00000033173.7
ENSMUST00000106483.2
polymerase (RNA) III (DNA directed) polypeptide E
chr2_-_20943413 0.28 ENSMUST00000140230.1
Rho GTPase activating protein 21
chr15_-_76206309 0.28 ENSMUST00000073418.6
ENSMUST00000171634.1
ENSMUST00000076442.5
plectin
chr5_+_112255813 0.28 ENSMUST00000031286.6
ENSMUST00000131673.1
ENSMUST00000112375.1
crystallin, beta B1
chr14_+_54476100 0.27 ENSMUST00000164766.1
ENSMUST00000164697.1
rad and gem related GTP binding protein 2
chr18_-_10030017 0.27 ENSMUST00000116669.1
ENSMUST00000092096.6
ubiquitin specific peptidase 14
chr18_-_43059418 0.27 ENSMUST00000025377.7
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform
chr15_-_79834261 0.26 ENSMUST00000148358.1
chromobox 6
chr4_-_57956283 0.26 ENSMUST00000030051.5
thioredoxin 1
chr2_+_163547148 0.25 ENSMUST00000109411.1
ENSMUST00000018094.6
hepatic nuclear factor 4, alpha
chr8_-_62123106 0.25 ENSMUST00000034052.6
ENSMUST00000034054.7
annexin A10
chr17_-_45592485 0.25 ENSMUST00000166119.1
solute carrier family 29 (nucleoside transporters), member 1
chr2_+_3713478 0.25 ENSMUST00000115053.2
family with sequence similarity 107, member B
chr5_-_38159457 0.25 ENSMUST00000031009.4
neuron specific gene family member 1
chr7_-_144751968 0.25 ENSMUST00000155175.1
anoctamin 1, calcium activated chloride channel
chr4_+_116685544 0.25 ENSMUST00000135573.1
ENSMUST00000151129.1
peroxiredoxin 1
chr8_-_107403197 0.24 ENSMUST00000003947.8
NAD(P)H dehydrogenase, quinone 1
chr2_+_3713449 0.24 ENSMUST00000027965.4
family with sequence similarity 107, member B
chr12_-_40248073 0.24 ENSMUST00000169926.1
interferon-related developmental regulator 1
chr7_+_84528964 0.24 ENSMUST00000180387.1
predicted gene 2115
chr8_-_126945841 0.23 ENSMUST00000179857.1
translocase of outer mitochondrial membrane 20 homolog (yeast)
chr15_-_76195710 0.23 ENSMUST00000023226.6
plectin
chr5_-_137613759 0.23 ENSMUST00000155251.1
ENSMUST00000124693.1
procollagen C-endopeptidase enhancer protein
chrX_+_74424534 0.23 ENSMUST00000135165.1
ENSMUST00000114128.1
ENSMUST00000114133.2
ENSMUST00000004330.3
inhibitor of kappaB kinase gamma
chr17_-_45592262 0.23 ENSMUST00000164769.1
solute carrier family 29 (nucleoside transporters), member 1
chr3_-_95228636 0.23 ENSMUST00000065482.5
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr10_-_62899118 0.23 ENSMUST00000174189.1
tet methylcytosine dioxygenase 1
chr17_-_56133817 0.22 ENSMUST00000167545.1
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
chr1_+_173673651 0.22 ENSMUST00000085876.4
pyrin domain containing 3
chr5_+_128601106 0.21 ENSMUST00000117102.2
frizzled homolog 10 (Drosophila)
chr5_+_34525797 0.21 ENSMUST00000125817.1
ENSMUST00000067638.7
SH3-domain binding protein 2
chr3_+_28805436 0.21 ENSMUST00000043867.5
ribosomal protein L22 like 1
chr18_+_73863672 0.21 ENSMUST00000134847.1
maestro
chr15_-_27681498 0.21 ENSMUST00000100739.3
family with sequence similarity 105, member A
chr11_-_120630126 0.20 ENSMUST00000106180.1
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian)
chrX_-_97377150 0.20 ENSMUST00000113832.1
ectodysplasin A2 receptor
chr3_-_116508035 0.20 ENSMUST00000153005.1
RNA 3'-terminal phosphate cyclase
chr6_-_120357342 0.20 ENSMUST00000163827.1
coiled-coil domain containing 77
chr1_-_173367638 0.20 ENSMUST00000005470.4
ENSMUST00000111220.1
cell adhesion molecule 3
chr5_+_66676098 0.20 ENSMUST00000031131.9
ubiquitin carboxy-terminal hydrolase L1
chr12_+_55398775 0.20 ENSMUST00000021412.8
proteasome (prosome, macropain) subunit, alpha type 6
chr15_+_11064764 0.20 ENSMUST00000061318.7
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 12
chr2_+_155775333 0.20 ENSMUST00000029141.5
matrix metallopeptidase 24
chr11_+_87582201 0.20 ENSMUST00000133202.1
septin 4
chr1_+_127306706 0.19 ENSMUST00000171405.1
mannoside acetylglucosaminyltransferase 5
chr11_+_80428598 0.19 ENSMUST00000173938.1
ENSMUST00000017572.7
proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr18_+_37955544 0.18 ENSMUST00000070709.2
ENSMUST00000177058.1
ENSMUST00000169360.2
ENSMUST00000163591.2
ENSMUST00000091932.5
RELT-like 2
chr11_+_62077018 0.18 ENSMUST00000092415.5
sperm antigen with calponin homology and coiled-coil domains 1
chr14_+_70077375 0.18 ENSMUST00000035908.1
early growth response 3
chr19_-_8839181 0.18 ENSMUST00000096259.4
guanine nucleotide binding protein (G protein), gamma 3
chr2_+_112261926 0.18 ENSMUST00000028553.3
NOP10 ribonucleoprotein
chr4_-_126321669 0.18 ENSMUST00000102617.4
ADP-ribosylhydrolase like 2
chr16_+_90220742 0.17 ENSMUST00000023707.9
superoxide dismutase 1, soluble
chrX_+_159372175 0.17 ENSMUST00000087143.6
eukaryotic translation initiation factor 1A, X-linked
chr5_-_49524809 0.17 ENSMUST00000087395.4
Kv channel interacting protein 4
chr16_+_20694908 0.17 ENSMUST00000056518.6
family with sequence similarity 131, member A
chrX_+_56779437 0.17 ENSMUST00000114773.3
four and a half LIM domains 1
chr5_-_21785115 0.17 ENSMUST00000115193.1
ENSMUST00000115192.1
ENSMUST00000115195.1
ENSMUST00000030771.5
DnaJ (Hsp40) homolog, subfamily C, member 2
chr14_+_67716262 0.17 ENSMUST00000150768.1
potassium channel tetramerisation domain containing 9
chr6_-_129533267 0.17 ENSMUST00000181594.1
RIKEN cDNA 1700101I11 gene
chrX_+_74424632 0.16 ENSMUST00000114129.2
ENSMUST00000132749.1
inhibitor of kappaB kinase gamma
chrX_+_71050160 0.16 ENSMUST00000082088.3
ENSMUST00000114629.3
mastermind-like domain containing 1
chr12_-_11150305 0.16 ENSMUST00000055673.1
potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3
chr2_+_155751117 0.16 ENSMUST00000029140.5
ENSMUST00000132608.1
protein C receptor, endothelial
chr7_-_105482197 0.16 ENSMUST00000047040.2
protein kinase C, delta binding protein
chr2_+_61711694 0.16 ENSMUST00000028278.7
proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
chrX_+_163911401 0.16 ENSMUST00000140845.1
adaptor-related protein complex 1, sigma 2 subunit
chr1_-_36535719 0.15 ENSMUST00000054665.4
ankyrin repeat domain 23
chr1_-_167285110 0.15 ENSMUST00000027839.8
uridine-cytidine kinase 2
chr6_-_67037399 0.15 ENSMUST00000043098.6
growth arrest and DNA-damage-inducible 45 alpha
chrX_+_56779699 0.15 ENSMUST00000114772.2
ENSMUST00000114768.3
ENSMUST00000155882.1
four and a half LIM domains 1
chr10_-_116473875 0.15 ENSMUST00000068233.4
potassium large conductance calcium-activated channel, subfamily M, beta member 4
chr7_+_127244511 0.15 ENSMUST00000052509.4
zinc finger protein 771
chr3_+_138217814 0.15 ENSMUST00000090171.5
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr2_-_44927161 0.14 ENSMUST00000130991.1
glycosyltransferase-like domain containing 1
chr6_+_124996681 0.14 ENSMUST00000032479.4
PILR alpha associated neural protein
chr3_+_87948666 0.14 ENSMUST00000005019.5
cellular retinoic acid binding protein II
chr12_-_85288419 0.13 ENSMUST00000121930.1
acylphosphatase 1, erythrocyte (common) type
chr8_+_79028587 0.13 ENSMUST00000119254.1
zinc finger protein 827
chr2_+_163995503 0.13 ENSMUST00000131288.1
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
chr11_+_101331069 0.13 ENSMUST00000017316.6
amine oxidase, copper containing 3
chr4_-_43558386 0.13 ENSMUST00000130353.1
talin 1
chr15_+_3270767 0.13 ENSMUST00000082424.4
ENSMUST00000159158.1
ENSMUST00000159216.1
ENSMUST00000160311.1
selenoprotein P, plasma, 1
chr19_+_6080029 0.12 ENSMUST00000149347.1
ENSMUST00000143303.1
cDNA sequence BC048609
chr16_-_76373827 0.12 ENSMUST00000121927.1
nuclear receptor interacting protein 1
chr1_-_75046639 0.12 ENSMUST00000152855.1
nonhomologous end-joining factor 1
chr13_+_14613242 0.12 ENSMUST00000170836.2
proteasome (prosome, macropain) subunit, alpha type 2
chr1_-_120074023 0.12 ENSMUST00000056089.7
transmembrane protein 37
chr19_-_12501996 0.12 ENSMUST00000045521.7
deltex 4 homolog (Drosophila)
chr6_-_34910869 0.12 ENSMUST00000081214.5
WD repeat domain 91
chr14_+_11553523 0.12 ENSMUST00000022264.6
protein tyrosine phosphatase, receptor type, G
chr17_+_27839974 0.12 ENSMUST00000071006.7
U1 small nuclear ribonucleoprotein C
chr2_-_27507656 0.12 ENSMUST00000154316.1
bromodomain containing 3
chr6_+_41951625 0.12 ENSMUST00000031898.4
seminal vesicle antigen-like 1
chr3_+_81999461 0.12 ENSMUST00000107736.1
acid-sensing (proton-gated) ion channel family member 5
chr17_-_24644933 0.11 ENSMUST00000019684.5
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2
chr10_+_80148263 0.11 ENSMUST00000099492.3
ENSMUST00000042057.5
midnolin
chr6_+_38918969 0.11 ENSMUST00000003017.6
thromboxane A synthase 1, platelet
chr2_+_28533355 0.11 ENSMUST00000113893.1
ENSMUST00000100241.3
ral guanine nucleotide dissociation stimulator
chr16_+_20651652 0.11 ENSMUST00000007212.8
proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
chr19_-_4037910 0.11 ENSMUST00000169613.1
glutathione S-transferase, pi 1
chr8_+_69822429 0.11 ENSMUST00000164890.1
ENSMUST00000034325.4
lysophosphatidic acid receptor 2
chr6_-_120357440 0.11 ENSMUST00000112703.1
coiled-coil domain containing 77
chr18_+_84088077 0.11 ENSMUST00000060223.2
zinc binding alcohol dehydrogenase, domain containing 2
chr5_-_65428354 0.11 ENSMUST00000131263.1
UDP-glucose dehydrogenase
chr2_+_181319714 0.11 ENSMUST00000098971.4
ENSMUST00000054622.8
ENSMUST00000108814.1
ENSMUST00000048608.9
ENSMUST00000108815.1
regulator of telomere elongation helicase 1
chr7_+_101321703 0.11 ENSMUST00000174291.1
ENSMUST00000167888.2
ENSMUST00000172662.1
ENSMUST00000173270.1
ENSMUST00000174083.1
START domain containing 10
chr2_+_119799514 0.11 ENSMUST00000028763.9
TYRO3 protein tyrosine kinase 3
chr2_+_25428699 0.11 ENSMUST00000102919.3
ATP-binding cassette, sub-family A (ABC1), member 2
chr18_+_37955685 0.10 ENSMUST00000169498.2
RELT-like 2
chr3_-_116508071 0.10 ENSMUST00000000348.8
RNA 3'-terminal phosphate cyclase
chr19_-_4042165 0.10 ENSMUST00000042700.9
glutathione S-transferase, pi 2
chr11_+_107479478 0.10 ENSMUST00000021063.6
ENSMUST00000106752.3
proteasome (prosome, macropain) 26S subunit, non-ATPase, 12
chr1_+_86064619 0.10 ENSMUST00000027432.8
proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
chr6_-_86793522 0.10 ENSMUST00000001187.8
annexin A4
chr19_+_8839298 0.10 ENSMUST00000160556.1
Bernardinelli-Seip congenital lipodystrophy 2 homolog (human)
chr11_-_43747963 0.10 ENSMUST00000048578.2
ENSMUST00000109278.1
tetratricopeptide repeat domain 1
chr6_+_5725812 0.10 ENSMUST00000115554.1
ENSMUST00000153942.1
dynein cytoplasmic 1 intermediate chain 1
chr5_+_22550391 0.10 ENSMUST00000181374.1
ENSMUST00000181764.1
ENSMUST00000181209.1
RIKEN cDNA 6030443J06 gene
chr3_+_122245625 0.10 ENSMUST00000178826.1
glutamate-cysteine ligase, modifier subunit
chr11_+_107479549 0.09 ENSMUST00000106750.4
proteasome (prosome, macropain) 26S subunit, non-ATPase, 12
chr8_+_125995102 0.09 ENSMUST00000046765.8
potassium channel, subfamily K, member 1
chr6_-_120357422 0.09 ENSMUST00000032283.5
coiled-coil domain containing 77
chr7_+_49759100 0.09 ENSMUST00000085272.5
HIV-1 tat interactive protein 2, homolog (human)
chr5_-_139484420 0.09 ENSMUST00000150992.1
zinc finger, AN1-type domain 2A
chr4_-_133874682 0.09 ENSMUST00000168974.2
ribosomal protein S6 kinase polypeptide 1
chr1_-_180199587 0.09 ENSMUST00000161743.1
aarF domain containing kinase 3
chr9_+_5345450 0.09 ENSMUST00000151332.1
caspase 12
chr6_+_51523901 0.09 ENSMUST00000049152.8
sorting nexin 10
chr7_-_126861648 0.09 ENSMUST00000129812.1
ENSMUST00000106342.1
INO80 complex subunit E
chr10_-_116473418 0.09 ENSMUST00000087965.4
ENSMUST00000164271.1
potassium large conductance calcium-activated channel, subfamily M, beta member 4
chr11_-_106256045 0.09 ENSMUST00000021048.6
FtsJ homolog 3 (E. coli)
chr9_+_124021965 0.09 ENSMUST00000039171.7
chemokine (C-C motif) receptor 3
chr8_+_79028317 0.09 ENSMUST00000087927.4
ENSMUST00000098614.2
zinc finger protein 827
chr2_-_25272380 0.09 ENSMUST00000028342.6
Sjogren's syndrome nuclear autoantigen 1
chr2_+_18064645 0.09 ENSMUST00000114680.2
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
chr17_-_24220738 0.08 ENSMUST00000024930.7
RIKEN cDNA 1600002H07 gene
chr9_-_106476104 0.08 ENSMUST00000156426.1
poly (ADP-ribose) polymerase family, member 3
chr8_+_123332676 0.08 ENSMUST00000010298.6
spire homolog 2 (Drosophila)
chr9_+_54950808 0.08 ENSMUST00000172407.1
proteasome (prosome, macropain) subunit, alpha type 4
chr14_-_21848924 0.08 ENSMUST00000124549.1
catechol-O-methyltransferase domain containing 1
chr14_+_120275669 0.08 ENSMUST00000088419.6
ENSMUST00000167459.1
muscleblind-like 2
chr15_-_79328154 0.08 ENSMUST00000166977.2
phospholipase A2, group VI
chr11_+_100619217 0.08 ENSMUST00000107376.1
NFKB inhibitor interacting Ras-like protein 2
chr7_-_114276107 0.08 ENSMUST00000033008.9
proteasome (prosome, macropain) subunit, alpha type 1
chr9_+_5345414 0.08 ENSMUST00000027009.4
caspase 12
chr3_+_95228732 0.08 ENSMUST00000053872.5
CDC42 small effector 1
chr16_-_30587537 0.08 ENSMUST00000117363.2
large subunit GTPase 1 homolog (S. cerevisiae)
chr9_+_54951104 0.08 ENSMUST00000171900.1
proteasome (prosome, macropain) subunit, alpha type 4

Network of associatons between targets according to the STRING database.

First level regulatory network of Nfe2_Bach1_Mafk

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:1903659 transforming growth factor beta activation(GO:0036363) regulation of complement-dependent cytotoxicity(GO:1903659) negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.2 0.7 GO:0036388 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) DNA replication preinitiation complex assembly(GO:0071163) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.2 0.9 GO:0090187 positive regulation of pancreatic juice secretion(GO:0090187)
0.2 1.1 GO:0060523 prostate epithelial cord elongation(GO:0060523)
0.2 0.5 GO:0015881 creatine transport(GO:0015881)
0.1 1.2 GO:0035754 B cell chemotaxis(GO:0035754)
0.1 3.6 GO:0032825 positive regulation of natural killer cell differentiation(GO:0032825)
0.1 0.4 GO:0072277 cell migration involved in vasculogenesis(GO:0035441) metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.1 0.4 GO:0002344 peripheral B cell selection(GO:0002343) B cell affinity maturation(GO:0002344)
0.1 0.3 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.1 0.3 GO:1902569 regulation of activation of JAK2 kinase activity(GO:0010534) activation of JAK2 kinase activity(GO:0042977) negative regulation of activation of JAK2 kinase activity(GO:1902569)
0.1 0.5 GO:0015862 uridine transport(GO:0015862)
0.1 0.3 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 0.5 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.1 0.2 GO:0035927 RNA import into mitochondrion(GO:0035927)
0.1 0.3 GO:0051684 maintenance of Golgi location(GO:0051684)
0.1 0.2 GO:0006222 UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.0 2.1 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.2 GO:0030167 proteoglycan catabolic process(GO:0030167) regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.0 0.1 GO:0006069 ethanol oxidation(GO:0006069)
0.0 0.3 GO:0061621 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.0 0.4 GO:0051409 response to nitrosative stress(GO:0051409)
0.0 0.3 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
0.0 0.2 GO:1904430 negative regulation of t-circle formation(GO:1904430)
0.0 0.5 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.3 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
0.0 0.2 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.0 0.3 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.4 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.1 GO:0070488 neutrophil aggregation(GO:0070488)
0.0 0.2 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.0 0.2 GO:0007412 axon target recognition(GO:0007412)
0.0 1.0 GO:0030220 platelet formation(GO:0030220)
0.0 0.1 GO:0046021 regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.0 0.1 GO:0043323 positive regulation of natural killer cell degranulation(GO:0043323)
0.0 0.1 GO:1990166 protein localization to site of double-strand break(GO:1990166)
0.0 0.1 GO:0001543 ovarian follicle rupture(GO:0001543)
0.0 0.3 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.9 GO:0071451 cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451)
0.0 0.2 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.0 0.1 GO:0070649 formin-nucleated actin cable assembly(GO:0070649)
0.0 0.2 GO:0051901 positive regulation of mitochondrial depolarization(GO:0051901)
0.0 0.2 GO:0098887 neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887)
0.0 0.2 GO:0015705 iodide transport(GO:0015705)
0.0 0.1 GO:0090238 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of arachidonic acid secretion(GO:0090238) positive regulation of ceramide biosynthetic process(GO:2000304)
0.0 0.6 GO:0045821 positive regulation of glycolytic process(GO:0045821)
0.0 0.2 GO:0038031 non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.0 0.9 GO:0030224 monocyte differentiation(GO:0030224)
0.0 0.1 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.0 0.4 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.1 GO:0045643 eosinophil differentiation(GO:0030222) regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.0 0.3 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0 0.1 GO:0035617 stress granule disassembly(GO:0035617)
0.0 0.1 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.1 GO:0072108 positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis(GO:0072108)
0.0 0.1 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.1 GO:0060075 regulation of resting membrane potential(GO:0060075)
0.0 0.2 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.1 GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.0 0.1 GO:0032380 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0 0.2 GO:2000400 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.0 0.1 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.1 GO:0035902 response to immobilization stress(GO:0035902)
0.0 0.1 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.0 0.2 GO:0097264 self proteolysis(GO:0097264)
0.0 0.1 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.0 0.1 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.0 0.1 GO:2000483 negative regulation of interleukin-8 secretion(GO:2000483)
0.0 0.2 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.1 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.1 GO:0060068 vagina development(GO:0060068)
0.0 0.1 GO:0032264 purine nucleotide salvage(GO:0032261) IMP salvage(GO:0032264)
0.0 0.2 GO:0048671 negative regulation of collateral sprouting(GO:0048671)
0.0 0.2 GO:0060297 regulation of sarcomere organization(GO:0060297)
0.0 0.1 GO:0044331 cell-cell adhesion mediated by cadherin(GO:0044331)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0036387 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.2 1.1 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.1 0.7 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 0.4 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.1 0.4 GO:1990257 piccolo-bassoon transport vesicle(GO:1990257)
0.1 1.1 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.1 1.0 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 0.2 GO:0097057 TRAF2-GSTP1 complex(GO:0097057)
0.1 0.3 GO:0005927 muscle tendon junction(GO:0005927)
0.1 0.3 GO:0032437 cuticular plate(GO:0032437)
0.1 0.5 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.2 GO:0090661 box H/ACA telomerase RNP complex(GO:0090661)
0.0 0.7 GO:0005838 proteasome regulatory particle(GO:0005838)
0.0 0.4 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.2 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.1 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.0 0.3 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.5 GO:0043196 varicosity(GO:0043196)
0.0 0.2 GO:0097227 sperm annulus(GO:0097227)
0.0 0.2 GO:0098845 postsynaptic endosome(GO:0098845)
0.0 0.5 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.1 GO:0032807 DNA ligase IV complex(GO:0032807)
0.0 0.1 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.0 0.1 GO:1990745 EARP complex(GO:1990745)
0.0 0.3 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.1 GO:0000243 commitment complex(GO:0000243)
0.0 0.1 GO:0031313 extrinsic component of endosome membrane(GO:0031313)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.2 0.5 GO:0005308 creatine transmembrane transporter activity(GO:0005308)
0.1 0.4 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.1 1.2 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.1 0.4 GO:1990450 linear polyubiquitin binding(GO:1990450)
0.1 0.7 GO:0002135 CTP binding(GO:0002135)
0.1 0.6 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.1 0.3 GO:0003963 RNA-3'-phosphate cyclase activity(GO:0003963)
0.1 0.3 GO:0070540 stearic acid binding(GO:0070540)
0.1 0.4 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.1 0.4 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.1 0.3 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 0.3 GO:0008422 beta-glucosidase activity(GO:0008422)
0.1 0.5 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.1 2.0 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.2 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.0 1.2 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.7 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.1 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0 0.7 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.5 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.0 0.1 GO:0052596 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.0 0.2 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.0 0.2 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.0 0.2 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.2 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.2 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.1 GO:0036132 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.0 0.1 GO:0003979 UDP-glucose 6-dehydrogenase activity(GO:0003979)
0.0 0.9 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.2 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 0.3 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.2 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.3 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 1.0 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.2 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 0.2 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.5 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 0.4 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.4 GO:0070628 proteasome binding(GO:0070628)
0.0 0.1 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.0 0.1 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.4 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.1 GO:0001962 alpha-1,3-galactosyltransferase activity(GO:0001962)
0.0 0.5 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.1 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.0 0.2 GO:0031432 titin binding(GO:0031432)
0.0 0.5 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.3 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.2 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.1 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.1 GO:1990446 U1 snRNP binding(GO:1990446)
0.0 0.1 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.0 0.1 GO:0019841 retinol binding(GO:0019841)
0.0 0.2 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.1 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.1 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.2 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.1 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.4 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.9 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 1.5 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.4 ST GAQ PATHWAY G alpha q Pathway
0.0 0.8 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.0 0.6 PID ATM PATHWAY ATM pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1 0.7 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 2.6 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.7 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.4 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.8 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.4 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.1 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.5 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.2 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.5 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.8 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 0.3 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.5 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.5 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules