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12D miR HR13_24

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Results for E2f7

Z-value: 1.01

Motif logo

Transcription factors associated with E2f7

Gene Symbol Gene ID Gene Info
ENSMUSG00000020185.10 E2F transcription factor 7

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
E2f7mm10_v2_chr10_+_110745433_1107455720.874.9e-04Click!

Activity profile of E2f7 motif

Sorted Z-values of E2f7 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_+_108383829 2.69 ENSMUST00000090561.3
ENSMUST00000102629.1
ENSMUST00000128089.1
proline/serine-rich coiled-coil 1
chr10_-_69352886 2.53 ENSMUST00000119827.1
ENSMUST00000020099.5
cyclin-dependent kinase 1
chr7_-_116308241 2.28 ENSMUST00000183057.1
ENSMUST00000182487.1
ENSMUST00000181998.1
pleckstrin homology domain containing, family A member 7
chr13_-_100775844 1.93 ENSMUST00000075550.3
centromere protein H
chr2_+_72476159 1.86 ENSMUST00000102691.4
cell division cycle associated 7
chr9_+_44084944 1.57 ENSMUST00000176416.1
ENSMUST00000065461.7
ubiquitin specific peptidase 2
chr15_+_102296256 1.53 ENSMUST00000064924.4
extra spindle poles-like 1 (S. cerevisiae)
chr11_+_102248842 1.50 ENSMUST00000100392.4
cDNA sequence BC030867
chr8_+_75109528 1.49 ENSMUST00000164309.1
minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae)
chr3_+_126363827 1.43 ENSMUST00000093976.2
arylsulfatase J
chr14_+_4334763 1.41 ENSMUST00000165466.1
RIKEN cDNA 2610042L04 gene
chr13_-_55329723 1.40 ENSMUST00000021941.7
Max dimerization protein 3
chr14_+_4855576 1.37 ENSMUST00000166776.1
predicted gene 3264
chr4_+_126556935 1.31 ENSMUST00000048391.8
claspin
chr2_+_72476225 1.22 ENSMUST00000157019.1
cell division cycle associated 7
chr4_+_108579445 1.21 ENSMUST00000102744.3
origin recognition complex, subunit 1
chr17_-_35516780 1.10 ENSMUST00000160885.1
ENSMUST00000159009.1
ENSMUST00000161012.1
transcription factor 19
chr14_-_7027449 1.07 ENSMUST00000170738.2
predicted gene 10406
chr2_-_26208281 1.07 ENSMUST00000054099.9
LIM homeobox protein 3
chr16_-_37384940 1.05 ENSMUST00000114781.1
ENSMUST00000114780.1
syntaxin binding protein 5-like
chr12_-_11265768 1.05 ENSMUST00000166117.1
Gen homolog 1, endonuclease (Drosophila)
chr2_+_112261926 0.99 ENSMUST00000028553.3
NOP10 ribonucleoprotein
chr14_+_3412614 0.96 ENSMUST00000170123.1
predicted gene 10409
chr4_+_136172367 0.96 ENSMUST00000061721.5
E2F transcription factor 2
chr7_+_28169744 0.94 ENSMUST00000042405.6
fibrillarin
chr4_+_126556994 0.92 ENSMUST00000147675.1
claspin
chr9_+_81863744 0.89 ENSMUST00000057067.3
meiosis-specific, MEI4 homolog (S. cerevisiae)
chr3_+_88532314 0.83 ENSMUST00000172699.1
mex3 homolog A (C. elegans)
chr6_-_88898664 0.83 ENSMUST00000058011.6
minichromosome maintenance deficient 2 mitotin (S. cerevisiae)
chr13_+_23581563 0.80 ENSMUST00000102968.1
histone cluster 1, H4d
chr18_+_56707725 0.75 ENSMUST00000025486.8
lamin B1
chr7_-_44548733 0.70 ENSMUST00000145956.1
ENSMUST00000049343.8
polymerase (DNA directed), delta 1, catalytic subunit
chr12_+_24708241 0.62 ENSMUST00000020980.5
ribonucleotide reductase M2
chr1_+_180568913 0.61 ENSMUST00000027777.6
poly (ADP-ribose) polymerase family, member 1
chr10_+_3973086 0.60 ENSMUST00000117291.1
ENSMUST00000120585.1
ENSMUST00000043735.7
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
chr4_+_132768325 0.59 ENSMUST00000102561.4
replication protein A2
chr1_-_128359610 0.59 ENSMUST00000027601.4
minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae)
chr9_-_58741543 0.53 ENSMUST00000098674.4
RIKEN cDNA 2410076I21 gene
chr11_+_43682038 0.50 ENSMUST00000094294.4
PWWP domain containing 2A
chr6_-_67037399 0.49 ENSMUST00000043098.6
growth arrest and DNA-damage-inducible 45 alpha
chr11_+_88047302 0.48 ENSMUST00000139129.2
serine/arginine-rich splicing factor 1
chr1_-_191183244 0.48 ENSMUST00000027941.8
activating transcription factor 3
chr12_+_24708984 0.47 ENSMUST00000154588.1
ribonucleotide reductase M2
chr11_-_70410010 0.47 ENSMUST00000019065.3
ENSMUST00000135148.1
proline, glutamic acid and leucine rich protein 1
chr1_-_156474249 0.44 ENSMUST00000051396.6
sterol O-acyltransferase 1
chr12_+_11265867 0.43 ENSMUST00000020931.5
structural maintenance of chromosomes 6
chr17_+_12916329 0.42 ENSMUST00000089024.6
ENSMUST00000151287.1
ENSMUST00000143961.1
t-complex protein 1
chr11_-_77513335 0.42 ENSMUST00000060417.4
transformation related protein 53 inducible protein 13
chrX_-_37085402 0.41 ENSMUST00000115231.3
ribosomal protein L39
chr19_+_8723478 0.39 ENSMUST00000180819.1
ENSMUST00000181422.1
small nucleolar RNA host gene (non-protein coding) 1
chr4_-_108579330 0.38 ENSMUST00000079213.5
PRP38 pre-mRNA processing factor 38 (yeast) domain containing A
chrX_-_73966329 0.38 ENSMUST00000114372.2
ENSMUST00000033761.6
host cell factor C1
chr7_-_120202104 0.34 ENSMUST00000033198.5
crystallin, mu
chr8_+_72319033 0.34 ENSMUST00000067912.7
Kruppel-like factor 2 (lung)
chr12_-_73286698 0.34 ENSMUST00000116420.2
TRM5 tRNA methyltransferase 5
chr14_-_24486994 0.33 ENSMUST00000026322.7
polymerase (RNA) III (DNA directed) polypeptide A
chr13_+_109685994 0.31 ENSMUST00000074103.5
phosphodiesterase 4D, cAMP specific
chr7_+_44816088 0.31 ENSMUST00000057195.9
ENSMUST00000107891.1
nucleoporin 62
chr19_-_10881677 0.30 ENSMUST00000128835.1
transmembrane protein 109
chr17_+_33524170 0.30 ENSMUST00000087623.6
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 10
chr11_-_95842409 0.29 ENSMUST00000059026.3
ABI gene family, member 3
chr7_+_35802593 0.29 ENSMUST00000052454.2
RIKEN cDNA E130304I02 gene
chr13_-_21783391 0.25 ENSMUST00000099704.3
histone cluster 1, H3i
chr11_+_43681998 0.25 ENSMUST00000061070.5
PWWP domain containing 2A
chr5_-_137533170 0.25 ENSMUST00000168746.1
ENSMUST00000170293.1
guanine nucleotide binding protein (G protein), beta 2
chr7_-_35802968 0.24 ENSMUST00000061586.4
zinc finger protein 507
chr10_-_128409632 0.23 ENSMUST00000172348.1
ENSMUST00000166608.1
ENSMUST00000164199.1
ENSMUST00000171370.1
ENSMUST00000026439.7
nucleic acid binding protein 2
chr10_-_117376955 0.23 ENSMUST00000069168.6
ENSMUST00000176686.1
cleavage and polyadenylation specific factor 6
chrX_+_68678541 0.22 ENSMUST00000088546.5
fragile X mental retardation syndrome 1
chr4_+_124714776 0.21 ENSMUST00000030734.4
splicing factor 3a, subunit 3
chr13_-_21753851 0.20 ENSMUST00000074752.2
histone cluster 1, H2ak
chr4_+_136286061 0.19 ENSMUST00000069195.4
ENSMUST00000130658.1
zinc finger protein 46
chr1_+_118389058 0.18 ENSMUST00000049404.6
ENSMUST00000070989.7
ENSMUST00000165223.1
ENSMUST00000178710.1
CLIP associating protein 1
chr15_+_98092569 0.18 ENSMUST00000163507.1
phosphofructokinase, muscle
chr9_+_64281575 0.18 ENSMUST00000034964.6
timeless interacting protein
chr15_+_79030874 0.18 ENSMUST00000171999.1
ENSMUST00000006544.7
glycine C-acetyltransferase (2-amino-3-ketobutyrate-coenzyme A ligase)
chr2_-_180920925 0.17 ENSMUST00000037299.8
ENSMUST00000108876.2
YTH domain family 1
chr14_-_54641347 0.17 ENSMUST00000067784.6
cadherin-like 24
chr11_+_87127267 0.16 ENSMUST00000139532.1
tripartite motif-containing 37
chr11_+_95842283 0.16 ENSMUST00000107714.2
ENSMUST00000107711.1
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
chr2_+_18672384 0.15 ENSMUST00000171845.1
ENSMUST00000061158.4
COMM domain containing 3
chr5_+_43662373 0.15 ENSMUST00000048150.8
coiled-coil and C2 domain containing 2A
chr10_-_117376922 0.15 ENSMUST00000177145.1
ENSMUST00000176670.1
cleavage and polyadenylation specific factor 6
chrX_+_68678624 0.14 ENSMUST00000114656.1
fragile X mental retardation syndrome 1
chr1_-_180813591 0.14 ENSMUST00000162118.1
ENSMUST00000159685.1
ENSMUST00000161308.1
H3 histone, family 3A
chr4_+_94739276 0.14 ENSMUST00000073939.6
ENSMUST00000102798.1
endothelial-specific receptor tyrosine kinase
chr7_-_45694369 0.13 ENSMUST00000040636.6
secretory blood group 1
chr17_+_25773769 0.13 ENSMUST00000134108.1
ENSMUST00000002350.4
nuclear prelamin A recognition factor-like
chr11_+_88047693 0.12 ENSMUST00000079866.4
serine/arginine-rich splicing factor 1
chr4_+_108619925 0.12 ENSMUST00000030320.6
coiled-coil and C2 domain containing 1B
chr17_-_35121990 0.11 ENSMUST00000173915.1
ENSMUST00000172765.2
casein kinase 2, beta polypeptide
chr7_-_142578139 0.11 ENSMUST00000136359.1
H19 fetal liver mRNA
chrX_+_153006461 0.11 ENSMUST00000095755.3
ubiquitin specific protease 51
chr1_+_86526688 0.10 ENSMUST00000045897.8
prothymosin alpha
chr7_+_66109474 0.09 ENSMUST00000036372.6
chondroitin sulfate synthase 1
chr15_-_33687840 0.08 ENSMUST00000042021.3
testis-specific protein, Y-encoded-like 5
chr6_-_30509706 0.08 ENSMUST00000064330.6
ENSMUST00000102991.2
ENSMUST00000115157.1
ENSMUST00000148638.1
transmembrane protein 209
chr19_-_10881723 0.08 ENSMUST00000144681.1
transmembrane protein 109
chr4_+_108459389 0.08 ENSMUST00000106673.1
ENSMUST00000043368.5
zinc finger, CCHC domain containing 11
chr3_-_144202300 0.08 ENSMUST00000121796.1
ENSMUST00000121112.1
LIM domain only 4
chr14_+_54254124 0.07 ENSMUST00000180359.1
abhydrolase domain containing 4
chr14_-_20388822 0.07 ENSMUST00000022345.6
DnaJ (Hsp40) homolog, subfamily C, member 9
chr13_-_92354943 0.04 ENSMUST00000022220.6
mutS homolog 3 (E. coli)
chr11_+_88047788 0.04 ENSMUST00000107920.3
serine/arginine-rich splicing factor 1
chr12_+_55836365 0.03 ENSMUST00000059250.6
breast cancer metastasis-suppressor 1-like
chr19_+_34550664 0.03 ENSMUST00000149829.1
ENSMUST00000102826.3
interferon-induced protein with tetratricopeptide repeats 2
chr5_+_129020069 0.03 ENSMUST00000031383.7
ENSMUST00000111343.1
RAN, member RAS oncogene family
chr18_+_35562158 0.03 ENSMUST00000166793.1
matrin 3
chr12_+_112146187 0.02 ENSMUST00000128402.2
kinesin family member 26A
chr2_+_147364989 0.02 ENSMUST00000109968.2
paired box gene 1
chr17_+_28691342 0.01 ENSMUST00000114758.1
ENSMUST00000004990.6
ENSMUST00000062694.8
ENSMUST00000114754.1
mitogen-activated protein kinase 14
chr10_+_11281583 0.01 ENSMUST00000070300.4
F-box protein 30
chr5_+_135187251 0.00 ENSMUST00000002825.5
bromodomain adjacent to zinc finger domain, 1B

Network of associatons between targets according to the STRING database.

First level regulatory network of E2f7

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.3 GO:0045218 zonula adherens maintenance(GO:0045218)
0.4 1.1 GO:0021526 medial motor column neuron differentiation(GO:0021526)
0.4 1.4 GO:0060025 regulation of synaptic activity(GO:0060025)
0.3 2.5 GO:0090166 Golgi disassembly(GO:0090166)
0.3 0.8 GO:0031662 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662)
0.2 1.2 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)
0.2 0.7 GO:0045004 DNA replication proofreading(GO:0045004)
0.2 2.2 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.2 0.6 GO:1904760 myofibroblast differentiation(GO:0036446) regulation of myofibroblast differentiation(GO:1904760)
0.2 1.0 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.2 0.9 GO:0018364 peptidyl-glutamine methylation(GO:0018364)
0.2 0.5 GO:1903984 positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.1 1.4 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 1.0 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
0.1 0.7 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.1 0.4 GO:0019046 release from viral latency(GO:0019046)
0.1 0.4 GO:1901254 regulation of translation at synapse, modulating synaptic transmission(GO:0099547) regulation of translation at postsynapse, modulating synaptic transmission(GO:0099578) positive regulation of intracellular transport of viral material(GO:1901254)
0.1 1.0 GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.1 0.3 GO:0032954 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
0.1 1.5 GO:0000212 meiotic spindle organization(GO:0000212)
0.1 0.6 GO:0046654 10-formyltetrahydrofolate metabolic process(GO:0009256) tetrahydrofolate biosynthetic process(GO:0046654)
0.1 1.6 GO:0051382 kinetochore assembly(GO:0051382)
0.1 0.3 GO:0070900 mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.1 0.4 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.1 0.6 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.1 2.7 GO:0090224 regulation of mitotic spindle organization(GO:0060236) regulation of spindle organization(GO:0090224)
0.1 1.6 GO:0045475 locomotor rhythm(GO:0045475) negative regulation of skeletal muscle tissue development(GO:0048642)
0.1 1.1 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.1 0.3 GO:0034616 response to laminar fluid shear stress(GO:0034616) cellular response to laminar fluid shear stress(GO:0071499)
0.1 1.5 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.4 GO:0042984 very-low-density lipoprotein particle assembly(GO:0034379) amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.0 0.2 GO:0000076 DNA replication checkpoint(GO:0000076)
0.0 0.3 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.8 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.0 0.5 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 1.1 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.0 0.1 GO:0031509 telomeric heterochromatin assembly(GO:0031509) negative regulation of chromosome condensation(GO:1902340)
0.0 0.2 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353) negative regulation of centriole replication(GO:0046600)
0.0 0.3 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.0 0.2 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.2 GO:0061622 glycolytic process through glucose-1-phosphate(GO:0061622)
0.0 0.6 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.0 0.1 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.0 0.3 GO:1901844 regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.1 GO:0048014 Tie signaling pathway(GO:0048014)
0.0 0.1 GO:0032364 oxygen homeostasis(GO:0032364)
0.0 1.1 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.0 0.2 GO:0070200 establishment of protein localization to telomere(GO:0070200)
0.0 0.2 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.5 GO:0071391 cellular response to estrogen stimulus(GO:0071391)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.0 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.2 1.0 GO:0090661 box H/ACA telomerase RNP complex(GO:0090661)
0.2 0.7 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.2 1.1 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.2 2.3 GO:0005915 zonula adherens(GO:0005915)
0.2 0.9 GO:0001651 dense fibrillar component(GO:0001651)
0.1 2.0 GO:0042555 MCM complex(GO:0042555)
0.1 0.4 GO:0035061 interchromatin granule(GO:0035061)
0.1 0.8 GO:0005638 lamin filament(GO:0005638)
0.1 0.4 GO:0019034 viral replication complex(GO:0019034) dendritic filopodium(GO:1902737)
0.1 5.4 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.4 GO:0042382 paraspeckles(GO:0042382)
0.0 0.2 GO:0070876 SOSS complex(GO:0070876)
0.0 0.2 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.6 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 1.2 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.9 GO:0000800 lateral element(GO:0000800)
0.0 0.3 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.0 0.4 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.2 GO:0031298 replication fork protection complex(GO:0031298)
0.0 0.1 GO:0097361 CIA complex(GO:0097361)
0.0 0.8 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.6 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 1.5 GO:0072686 mitotic spindle(GO:0072686)
0.0 0.3 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.1 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.3 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 2.4 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.4 GO:0071011 precatalytic spliceosome(GO:0071011)
0.0 1.6 GO:0000776 kinetochore(GO:0000776)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.1 GO:0043515 kinetochore binding(GO:0043515)
0.4 2.2 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.2 1.1 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.2 2.5 GO:0070097 delta-catenin binding(GO:0070097)
0.2 2.3 GO:0003688 DNA replication origin binding(GO:0003688)
0.2 0.6 GO:0004488 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
0.1 1.0 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.1 2.5 GO:0035173 histone kinase activity(GO:0035173)
0.1 0.9 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.1 0.9 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.1 0.6 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.1 1.4 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.1 0.6 GO:0003909 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.1 0.8 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.1 0.4 GO:0033592 RNA strand annealing activity(GO:0033592)
0.1 0.3 GO:0051425 PTB domain binding(GO:0051425)
0.0 0.7 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.0 0.2 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.1 GO:0008107 galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.0 0.3 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.0 0.4 GO:0043996 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 0.3 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 1.3 GO:0030332 cyclin binding(GO:0030332)
0.0 0.1 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0 0.8 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.2 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.3 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.6 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.1 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.0 1.3 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.0 GO:0032139 dinucleotide insertion or deletion binding(GO:0032139) single guanine insertion binding(GO:0032142)
0.0 0.4 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.4 GO:0044183 protein binding involved in protein folding(GO:0044183)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 3.8 PID ATR PATHWAY ATR signaling pathway
0.1 1.0 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 2.3 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.4 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 3.4 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 1.9 PID E2F PATHWAY E2F transcription factor network
0.0 0.6 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 1.0 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.8 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.5 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.7 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.2 2.9 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.2 1.0 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.2 1.4 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 1.3 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.1 1.1 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.0 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 0.5 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.4 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.6 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 1.8 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.3 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 1.0 REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM Genes involved in Transport of Mature Transcript to Cytoplasm
0.0 0.4 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.4 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants