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12D miR HR13_24

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Results for Klf3

Z-value: 0.28

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Transcription factors associated with Klf3

Gene Symbol Gene ID Gene Info
ENSMUSG00000029178.8 Kruppel-like factor 3 (basic)

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Klf3mm10_v2_chr5_+_64812336_648123500.186.0e-01Click!

Activity profile of Klf3 motif

Sorted Z-values of Klf3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chrX_-_102251852 0.89 ENSMUST00000101336.3
ENSMUST00000136277.1
Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1
chrX_-_102252154 0.80 ENSMUST00000050551.3
Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1
chr1_+_72824482 0.43 ENSMUST00000047328.4
insulin-like growth factor binding protein 2
chr7_-_103827922 0.33 ENSMUST00000023934.6
ENSMUST00000153218.1
hemoglobin, beta adult s chain
chr11_+_99041237 0.28 ENSMUST00000017637.6
insulin-like growth factor binding protein 4
chr12_+_87026564 0.18 ENSMUST00000110187.1
ENSMUST00000156162.1
transmembrane protein 63c
chr12_+_87026286 0.17 ENSMUST00000146292.1
transmembrane protein 63c
chrX_-_74246534 0.15 ENSMUST00000101454.2
ENSMUST00000033699.6
filamin, alpha
chrX_-_74246364 0.14 ENSMUST00000130007.1
filamin, alpha
chr10_-_12964252 0.14 ENSMUST00000163425.1
ENSMUST00000042861.5
syntaxin 11
chr2_+_163547148 0.12 ENSMUST00000109411.1
ENSMUST00000018094.6
hepatic nuclear factor 4, alpha
chr14_+_123659971 0.09 ENSMUST00000049681.7
integrin, beta-like 1
chr19_+_10041548 0.07 ENSMUST00000115995.2
fatty acid desaturase 3
chr19_-_53390559 0.06 ENSMUST00000025997.5
survival motor neuron domain containing 1
chr3_+_90080442 0.05 ENSMUST00000127955.1
tropomyosin 3, gamma
chr11_+_98701263 0.04 ENSMUST00000038886.2
colony stimulating factor 3 (granulocyte)
chr5_+_137630116 0.03 ENSMUST00000175968.1
leucine-rich repeats and calponin homology (CH) domain containing 4
chr1_+_86064619 0.03 ENSMUST00000027432.8
proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
chr3_+_83026147 0.02 ENSMUST00000166581.1
ENSMUST00000029630.9
fibrinogen alpha chain
chr3_+_90079540 0.02 ENSMUST00000029549.9
ENSMUST00000118566.1
ENSMUST00000119158.1
tropomyosin 3, gamma
chr4_-_41774097 0.02 ENSMUST00000108036.1
ENSMUST00000173865.1
ENSMUST00000108037.2
ENSMUST00000108032.2
chemokine (C-C motif) ligand 27A
chr7_-_17027853 0.02 ENSMUST00000003183.5
protein phosphatase 5, catalytic subunit
chr7_-_17027807 0.01 ENSMUST00000142597.1
protein phosphatase 5, catalytic subunit
chr1_+_107511489 0.01 ENSMUST00000064916.2
serine (or cysteine) peptidase inhibitor, clade B, member 2
chr1_+_107511416 0.01 ENSMUST00000009356.4
serine (or cysteine) peptidase inhibitor, clade B, member 2
chr3_-_88334428 0.00 ENSMUST00000107552.1
transmembrane protein 79
chr9_-_95815389 0.00 ENSMUST00000119760.1
plastin 1 (I-isoform)

Network of associatons between targets according to the STRING database.

First level regulatory network of Klf3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.7 GO:0071105 response to interleukin-9(GO:0071104) response to interleukin-11(GO:0071105)
0.1 0.3 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.0 0.1 GO:1902569 regulation of activation of JAK2 kinase activity(GO:0010534) activation of JAK2 kinase activity(GO:0042977) negative regulation of activation of JAK2 kinase activity(GO:1902569)
0.0 0.7 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0 0.1 GO:0043312 neutrophil degranulation(GO:0043312)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.1 0.3 GO:0031523 Myb complex(GO:0031523)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 GO:0050693 LBD domain binding(GO:0050693)
0.1 0.3 GO:0031720 haptoglobin binding(GO:0031720)
0.1 0.7 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 0.3 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.0 0.1 GO:0070540 stearic acid binding(GO:0070540)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.8 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)