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12D miR HR13_24

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Results for Ebf3

Z-value: 1.14

Motif logo

Transcription factors associated with Ebf3

Gene Symbol Gene ID Gene Info
ENSMUSG00000010476.7 early B cell factor 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Ebf3mm10_v2_chr7_-_137314394_1373144450.884.1e-04Click!

Activity profile of Ebf3 motif

Sorted Z-values of Ebf3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_129121234 5.31 ENSMUST00000030572.3
hippocalcin
chr12_+_109453455 4.58 ENSMUST00000109844.4
ENSMUST00000109842.2
ENSMUST00000109843.1
ENSMUST00000109846.4
ENSMUST00000173539.1
ENSMUST00000109841.2
delta-like 1 homolog (Drosophila)
chr4_-_129121699 4.16 ENSMUST00000135763.1
ENSMUST00000149763.1
ENSMUST00000164649.1
hippocalcin
chr12_-_103904887 4.04 ENSMUST00000074051.5
serine (or cysteine) peptidase inhibitor, clade A, member 1C
chr12_-_103773592 3.10 ENSMUST00000078869.5
serine (or cysteine) peptidase inhibitor, clade A, member 1D
chr5_+_30711564 2.33 ENSMUST00000114729.1
dihydropyrimidinase-like 5
chr5_+_30711849 2.30 ENSMUST00000088081.4
ENSMUST00000101442.3
dihydropyrimidinase-like 5
chr15_+_82256023 2.28 ENSMUST00000143238.1
RIKEN cDNA 1500009C09 gene
chrX_+_48108912 2.20 ENSMUST00000114998.1
ENSMUST00000115000.3
X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound
chr9_-_97018823 2.07 ENSMUST00000055433.4
splA/ryanodine receptor domain and SOCS box containing 4
chr11_-_72411695 2.06 ENSMUST00000108500.1
ENSMUST00000050226.6
smoothelin-like 2
chr11_-_98053415 2.06 ENSMUST00000017544.2
SH3 and cysteine rich domain 2
chr1_+_172482199 1.99 ENSMUST00000135267.1
ENSMUST00000052629.6
ENSMUST00000111235.2
immunoglobulin superfamily, member 9
chr2_+_55437100 1.83 ENSMUST00000112633.2
ENSMUST00000112632.1
potassium inwardly-rectifying channel, subfamily J, member 3
chr1_+_172481788 1.77 ENSMUST00000127052.1
immunoglobulin superfamily, member 9
chr7_+_28982832 1.63 ENSMUST00000085835.6
mitogen-activated protein kinase kinase kinase kinase 1
chrX_+_159459125 1.54 ENSMUST00000043151.5
ENSMUST00000112470.1
ENSMUST00000156172.1
MAP7 domain containing 2
chr1_+_74278550 1.50 ENSMUST00000077985.3
G protein-coupled bile acid receptor 1
chr4_-_148130678 1.50 ENSMUST00000030862.4
dorsal inhibitory axon guidance protein
chr1_+_172312367 1.48 ENSMUST00000039506.9
immunoglobulin superfamily, member 8
chr2_+_25372315 1.46 ENSMUST00000028329.6
ENSMUST00000114293.2
ENSMUST00000100323.2
suppressor APC domain containing 2
chr1_-_74749221 1.40 ENSMUST00000081636.6
protein kinase, AMP-activated, gamma 3 non-catatlytic subunit
chr1_-_173367638 1.36 ENSMUST00000005470.4
ENSMUST00000111220.1
cell adhesion molecule 3
chr10_-_67912620 1.35 ENSMUST00000064656.7
zinc finger protein 365
chr10_-_88146867 1.28 ENSMUST00000164121.1
ENSMUST00000164803.1
ENSMUST00000168163.1
ENSMUST00000048518.9
PARP1 binding protein
chr4_-_137796350 1.26 ENSMUST00000030551.4
alkaline phosphatase, liver/bone/kidney
chr10_-_41303171 1.23 ENSMUST00000043814.3
FIG4 homolog (S. cerevisiae)
chr11_-_11808923 1.22 ENSMUST00000109664.1
ENSMUST00000150714.1
ENSMUST00000047689.4
ENSMUST00000171938.1
ENSMUST00000171080.1
fidgetin-like 1
chr9_+_103305156 1.19 ENSMUST00000035164.3
topoisomerase (DNA) II binding protein 1
chr15_+_78913916 1.17 ENSMUST00000089378.4
pyridoxal (pyridoxine, vitamin B6) phosphatase
chr7_+_143107252 1.16 ENSMUST00000009689.4
potassium voltage-gated channel, subfamily Q, member 1
chr14_+_62292475 1.14 ENSMUST00000166879.1
ribonuclease H2, subunit B
chr14_-_62292959 1.08 ENSMUST00000063169.8
deleted in lymphocytic leukemia, 7
chr13_+_55399648 1.07 ENSMUST00000057167.7
solute carrier family 34 (sodium phosphate), member 1
chr11_+_4064841 1.07 ENSMUST00000068322.6
SEC14-like 3 (S. cerevisiae)
chr1_+_75400070 1.06 ENSMUST00000113589.1
SPEG complex locus
chr8_-_105851981 1.05 ENSMUST00000040776.4
centromere protein T
chr4_+_122996035 1.04 ENSMUST00000030407.7
v-myc myelocytomatosis viral oncogene homolog, lung carcinoma derived (avian)
chr11_+_76679757 1.02 ENSMUST00000062024.2
tumor suppressor candidate 5
chr9_+_95637601 1.01 ENSMUST00000015498.8
procollagen C-endopeptidase enhancer 2
chr4_-_131821516 0.98 ENSMUST00000097860.2
protein tyrosine phosphatase, receptor type, U
chr9_-_110743653 0.97 ENSMUST00000166716.1
parathyroid hormone 1 receptor
chr2_+_181763315 0.96 ENSMUST00000081125.4
myelin transcription factor 1
chr10_+_63100156 0.95 ENSMUST00000044059.3
atonal homolog 7 (Drosophila)
chr12_-_109068173 0.95 ENSMUST00000073156.7
brain-enriched guanylate kinase-associated
chr19_-_10869757 0.95 ENSMUST00000120524.1
ENSMUST00000025645.7
transmembrane protein 132A
chr5_-_38159457 0.94 ENSMUST00000031009.4
neuron specific gene family member 1
chr14_+_54476100 0.92 ENSMUST00000164766.1
ENSMUST00000164697.1
rad and gem related GTP binding protein 2
chr17_+_84626458 0.90 ENSMUST00000025101.8
dynein cytoplasmic 2 light intermediate chain 1
chr16_+_21891969 0.89 ENSMUST00000042065.6
mitogen-activated protein kinase kinase kinase 13
chr9_+_108479849 0.89 ENSMUST00000065014.4
laminin, beta 2
chr3_-_108415552 0.87 ENSMUST00000090558.3
cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila)
chr5_+_135806859 0.87 ENSMUST00000126232.1
serine/arginine repetitive matrix 3
chr16_-_37384915 0.86 ENSMUST00000114787.1
ENSMUST00000114782.1
ENSMUST00000023526.2
ENSMUST00000114775.1
syntaxin binding protein 5-like
chr11_-_3539228 0.86 ENSMUST00000075118.3
ENSMUST00000136243.1
ENSMUST00000170588.1
ENSMUST00000020721.8
smoothelin
chr2_+_55435918 0.84 ENSMUST00000067101.3
potassium inwardly-rectifying channel, subfamily J, member 3
chr3_+_88043098 0.82 ENSMUST00000166021.1
ENSMUST00000029707.7
G patch domain containing 4
chr16_+_32914094 0.82 ENSMUST00000023491.6
ENSMUST00000170899.1
ENSMUST00000171118.1
ENSMUST00000170201.1
ENSMUST00000165616.1
ENSMUST00000135193.2
leucine-rich repeats and calponin homology (CH) domain containing 3
chr8_+_70493156 0.82 ENSMUST00000008032.7
cytokine receptor-like factor 1
chr16_-_37384940 0.82 ENSMUST00000114781.1
ENSMUST00000114780.1
syntaxin binding protein 5-like
chr4_+_133240778 0.80 ENSMUST00000030677.6
mitogen-activated protein kinase kinase kinase 6
chr5_+_37245792 0.78 ENSMUST00000031004.7
collapsin response mediator protein 1
chr9_+_30942541 0.78 ENSMUST00000068135.6
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 8
chr6_-_95718800 0.76 ENSMUST00000079847.5
succinate-Coenzyme A ligase, GDP-forming, beta subunit
chr7_+_79743142 0.75 ENSMUST00000035622.7
WD repeat domain 93
chr14_+_62332068 0.75 ENSMUST00000022499.6
ribonuclease H2, subunit B
chr7_+_101378183 0.73 ENSMUST00000084895.5
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr19_+_43440404 0.72 ENSMUST00000165311.1
cyclin M1
chr7_+_28180272 0.72 ENSMUST00000173223.1
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
chr17_-_32388885 0.70 ENSMUST00000087703.5
ENSMUST00000170603.1
widely-interspaced zinc finger motifs
chr3_+_26331150 0.70 ENSMUST00000099182.2
RIKEN cDNA A830092H15 gene
chr10_-_79645732 0.69 ENSMUST00000095464.2
outer dense fiber of sperm tails 3-like 2
chr11_+_101316917 0.68 ENSMUST00000151385.1
proteaseome (prosome, macropain) activator subunit 3 (PA28 gamma, Ki)
chr18_+_34624621 0.66 ENSMUST00000167161.1
kinesin family member 20A
chr7_+_27607997 0.65 ENSMUST00000142365.1
thymoma viral proto-oncogene 2
chr3_+_68494208 0.65 ENSMUST00000182719.1
schwannomin interacting protein 1
chr15_-_78495059 0.64 ENSMUST00000089398.1
interleukin 2 receptor, beta chain
chr17_-_50094277 0.63 ENSMUST00000113195.1
raftlin lipid raft linker 1
chr4_+_9269285 0.62 ENSMUST00000038841.7
clavesin 1
chr18_+_84088077 0.61 ENSMUST00000060223.2
zinc binding alcohol dehydrogenase, domain containing 2
chr7_+_62376979 0.60 ENSMUST00000080403.5
melanoma antigen, family L, 2
chr9_-_103222063 0.60 ENSMUST00000170904.1
transferrin
chr10_-_80671976 0.59 ENSMUST00000003433.6
MAP kinase-interacting serine/threonine kinase 2
chr10_+_80151154 0.58 ENSMUST00000146516.1
ENSMUST00000144526.1
midnolin
chr3_+_97158767 0.58 ENSMUST00000090759.4
acid phosphatase 6, lysophosphatidic
chr17_+_80944611 0.57 ENSMUST00000025092.4
transmembrane protein 178
chr5_-_142509653 0.57 ENSMUST00000110784.1
Ras association and DIL domains
chr3_+_145987835 0.57 ENSMUST00000039517.6
synapse defective 1, Rho GTPase, homolog 2 (C. elegans)
chr15_-_76200577 0.57 ENSMUST00000169108.1
ENSMUST00000170728.1
plectin
chr7_-_127020321 0.56 ENSMUST00000032918.2
PAXIP1 associated glutamate rich protein 1A
chr7_+_28180226 0.56 ENSMUST00000172467.1
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
chr11_-_94976327 0.56 ENSMUST00000103162.1
ENSMUST00000166320.1
sarcoglycan, alpha (dystrophin-associated glycoprotein)
chr5_+_65348386 0.55 ENSMUST00000031096.7
klotho beta
chr9_+_119402444 0.55 ENSMUST00000035093.8
ENSMUST00000165044.1
activin receptor IIB
chr11_+_16951371 0.55 ENSMUST00000109635.1
ENSMUST00000061327.1
F-box protein 48
chr7_-_127615226 0.54 ENSMUST00000084564.3
zinc finger protein 629
chr11_-_102365111 0.54 ENSMUST00000006749.9
solute carrier family 4 (anion exchanger), member 1
chr11_-_120378692 0.53 ENSMUST00000026448.9
RIKEN cDNA 2310003H01 gene
chr7_-_4844665 0.53 ENSMUST00000066041.5
ENSMUST00000172377.1
shisa homolog 7 (Xenopus laevis)
chr2_+_152754156 0.53 ENSMUST00000010020.5
cytochrome c oxidase subunit IV isoform 2
chr7_+_105404568 0.53 ENSMUST00000033187.4
cyclic nucleotide gated channel alpha 4
chr19_+_8871512 0.52 ENSMUST00000166407.1
UBX domain protein 1
chr17_+_27685197 0.52 ENSMUST00000097360.2
protein kinase C and casein kinase substrate in neurons 1
chr11_-_69837781 0.52 ENSMUST00000108634.2
neuroligin 2
chr3_+_115888139 0.52 ENSMUST00000106505.1
ENSMUST00000043342.9
DPH5 homolog (S. cerevisiae)
chr7_-_45179539 0.52 ENSMUST00000179443.1
predicted gene 581
chr7_-_45824750 0.51 ENSMUST00000071937.5
potassium inwardly-rectifying channel, subfamily J, member 14
chr19_+_3986564 0.51 ENSMUST00000054030.7
aspartoacylase (aminoacylase) 3
chrX_+_75382384 0.49 ENSMUST00000033541.4
FUN14 domain containing 2
chr14_-_101609033 0.49 ENSMUST00000161991.1
ENSMUST00000100340.3
TBC1 domain family, member 4
chr1_-_57377476 0.49 ENSMUST00000181949.1
RIKEN cDNA 4930558J18 gene
chr4_+_128688726 0.49 ENSMUST00000106080.1
polyhomeotic-like 2 (Drosophila)
chr11_+_83409137 0.48 ENSMUST00000021022.3
RAS-like, family 10, member B
chr7_+_4690760 0.47 ENSMUST00000048248.7
BR serine/threonine kinase 1
chr14_+_67745229 0.47 ENSMUST00000111095.2
gonadotropin releasing hormone 1
chr8_-_81014866 0.47 ENSMUST00000042724.6
ubiquitin specific peptidase 38
chr15_-_66812593 0.46 ENSMUST00000100572.3
src-like adaptor
chr9_-_67043743 0.45 ENSMUST00000113695.1
tropomyosin 1, alpha
chr7_-_127615208 0.45 ENSMUST00000122066.1
zinc finger protein 629
chr19_+_8871636 0.45 ENSMUST00000096255.5
UBX domain protein 1
chr2_+_154548888 0.45 ENSMUST00000045116.4
ENSMUST00000109709.3
RIKEN cDNA 1700003F12 gene
chr10_+_80329953 0.45 ENSMUST00000105358.1
ENSMUST00000105357.1
ENSMUST00000105354.1
ENSMUST00000105355.1
receptor accessory protein 6
chr11_-_95842409 0.45 ENSMUST00000059026.3
ABI gene family, member 3
chr9_-_67043709 0.45 ENSMUST00000113689.1
ENSMUST00000113684.1
tropomyosin 1, alpha
chr7_+_4690604 0.45 ENSMUST00000120836.1
BR serine/threonine kinase 1
chr11_-_120630126 0.44 ENSMUST00000106180.1
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian)
chr9_+_70207342 0.43 ENSMUST00000034745.7
myosin IE
chr6_-_124542281 0.43 ENSMUST00000159463.1
ENSMUST00000162844.1
ENSMUST00000160505.1
ENSMUST00000162443.1
complement component 1, s subcomponent
chrX_+_56787701 0.43 ENSMUST00000151033.1
four and a half LIM domains 1
chr15_+_85336350 0.43 ENSMUST00000163242.1
ataxin 10
chr5_-_37824580 0.42 ENSMUST00000063116.9
msh homeobox 1
chr4_+_148130883 0.42 ENSMUST00000084129.2
MAD2 mitotic arrest deficient-like 2
chr10_+_88147061 0.42 ENSMUST00000169309.1
nucleoporin 37
chr13_+_91741507 0.41 ENSMUST00000022120.4
acyl-CoA thioesterase 12
chr7_+_27607748 0.41 ENSMUST00000136962.1
thymoma viral proto-oncogene 2
chr9_-_103228420 0.41 ENSMUST00000126359.1
transferrin
chr9_+_121366958 0.40 ENSMUST00000045903.6
trafficking protein, kinesin binding 1
chr10_+_57632108 0.40 ENSMUST00000177438.1
protein kinase inhibitor beta, cAMP dependent, testis specific
chr5_-_135078224 0.40 ENSMUST00000067935.4
ENSMUST00000076203.2
vacuolar protein sorting 37D (yeast)
chr1_+_156558844 0.39 ENSMUST00000166172.2
ENSMUST00000027888.6
v-abl Abelson murine leukemia viral oncogene 2 (arg, Abelson-related gene)
chr11_+_98927785 0.39 ENSMUST00000107474.1
retinoic acid receptor, alpha
chr11_-_97744659 0.39 ENSMUST00000018691.8
phosphatidylinositol-5-phosphate 4-kinase, type II, beta
chr11_+_101246960 0.39 ENSMUST00000107282.3
receptor (calcitonin) activity modifying protein 2
chr10_+_88146992 0.39 ENSMUST00000052355.7
nucleoporin 37
chr1_+_74375203 0.39 ENSMUST00000027368.5
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1
chr11_+_70432627 0.38 ENSMUST00000084954.6
ENSMUST00000108568.3
ENSMUST00000079056.2
ENSMUST00000102564.4
ENSMUST00000124943.1
ENSMUST00000150076.1
ENSMUST00000102563.1
arrestin, beta 2
chr12_-_85288419 0.38 ENSMUST00000121930.1
acylphosphatase 1, erythrocyte (common) type
chr7_+_45785331 0.38 ENSMUST00000120005.1
ENSMUST00000123585.1
lemur tyrosine kinase 3
chr2_+_125068118 0.37 ENSMUST00000070353.3
solute carrier family 24, member 5
chr5_+_64160207 0.37 ENSMUST00000101195.2
TBC1 domain family, member 1
chr1_+_167598450 0.37 ENSMUST00000111386.1
ENSMUST00000111384.1
retinoid X receptor gamma
chr7_+_19411086 0.37 ENSMUST00000003643.1
creatine kinase, muscle
chr7_-_25615874 0.36 ENSMUST00000098663.1
predicted gene 7092
chr2_+_32363680 0.36 ENSMUST00000113331.1
ENSMUST00000113338.2
CDKN1A interacting zinc finger protein 1
chr5_-_139130159 0.36 ENSMUST00000129851.1
protein kinase, cAMP dependent regulatory, type I beta
chrX_-_145348932 0.36 ENSMUST00000040084.9
ENSMUST00000123443.1
lipoma HMGIC fusion partner-like 1
chr2_-_128687354 0.35 ENSMUST00000110332.1
ENSMUST00000110333.1
ENSMUST00000014499.3
anaphase promoting complex subunit 1
chr4_-_132261596 0.35 ENSMUST00000105964.1
glucocorticoid modulatory element binding protein 1
chr3_-_115888086 0.34 ENSMUST00000067500.5
RIKEN cDNA A930005H10 gene
chr11_+_101246405 0.34 ENSMUST00000122006.1
ENSMUST00000151830.1
receptor (calcitonin) activity modifying protein 2
chr14_-_61037937 0.34 ENSMUST00000111236.2
tumor necrosis factor receptor superfamily, member 19
chr7_+_101394361 0.34 ENSMUST00000154239.1
ENSMUST00000098243.2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr2_+_127590321 0.34 ENSMUST00000146131.1
mitochondrial ribosomal protein S5
chr10_+_60346851 0.34 ENSMUST00000020301.7
ENSMUST00000105460.1
ENSMUST00000170507.1
RIKEN cDNA 4632428N05 gene
chr10_+_57631981 0.34 ENSMUST00000095668.3
ENSMUST00000075992.5
protein kinase inhibitor beta, cAMP dependent, testis specific
chr11_+_4257557 0.33 ENSMUST00000066283.5
leukemia inhibitory factor
chr5_+_145167207 0.33 ENSMUST00000160629.1
ENSMUST00000070487.5
ENSMUST00000160422.1
ENSMUST00000162244.1
cleavage and polyadenylation specific factor 4
chr17_-_24644933 0.33 ENSMUST00000019684.5
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2
chr19_+_37550397 0.33 ENSMUST00000066439.6
exocyst complex component 6
chr11_+_95842283 0.33 ENSMUST00000107714.2
ENSMUST00000107711.1
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
chr7_-_45920830 0.32 ENSMUST00000164119.1
epithelial membrane protein 3
chr17_+_45563928 0.32 ENSMUST00000041353.6
solute carrier family 35, member B2
chr19_+_38481057 0.32 ENSMUST00000182481.1
phospholipase C, epsilon 1
chrX_-_162964557 0.31 ENSMUST00000038769.2
S100 calcium binding protein G
chr8_+_84970068 0.31 ENSMUST00000164807.1
peroxiredoxin 2
chr3_+_95427575 0.30 ENSMUST00000181809.1
predicted gene 4349
chr12_-_31713873 0.30 ENSMUST00000057783.4
ENSMUST00000174480.2
ENSMUST00000176710.1
G protein-coupled receptor 22
chr11_+_117308135 0.30 ENSMUST00000153668.1
septin 9
chr6_+_113237843 0.29 ENSMUST00000113146.2
myotubularin related protein 14
chr3_+_90072641 0.29 ENSMUST00000121503.1
ENSMUST00000119570.1
ENSMUST00000062193.9
tropomyosin 3, gamma
chr13_+_54949388 0.29 ENSMUST00000026994.7
ENSMUST00000109994.2
unc-5 homolog A (C. elegans)
chr4_-_116627478 0.29 ENSMUST00000081182.4
ENSMUST00000030457.5
nuclear autoantigenic sperm protein (histone-binding)
chr17_+_44777294 0.28 ENSMUST00000127798.1
suppressor of Ty 3
chr11_-_95699143 0.28 ENSMUST00000062249.2
predicted gene 9796
chr2_+_30441831 0.27 ENSMUST00000131476.1
protein phosphatase 2A, regulatory subunit B (PR 53)
chr15_-_98677451 0.27 ENSMUST00000120997.1
ENSMUST00000109149.2
ENSMUST00000003451.4
Rho family GTPase 1
chr13_-_49309217 0.27 ENSMUST00000110087.2
FYVE, RhoGEF and PH domain containing 3
chr13_-_3918157 0.27 ENSMUST00000091853.4
neuroepithelial cell transforming gene 1
chr9_-_78368167 0.27 ENSMUST00000071991.5
developmental pluripotency associated 5A
chr2_+_180582712 0.27 ENSMUST00000029085.8
MRG/MORF4L binding protein
chr6_-_91116785 0.27 ENSMUST00000113509.1
ENSMUST00000032179.7
nucleoporin 210
chr2_+_156196642 0.27 ENSMUST00000037401.8
PHD finger protein 20
chr4_+_141213948 0.26 ENSMUST00000097813.2
REM2 and RAB-like small GTPase 1
chr4_-_152038568 0.26 ENSMUST00000030792.1
taste receptor, type 1, member 1
chr6_-_119848093 0.26 ENSMUST00000079582.4
ELKS/RAB6-interacting/CAST family member 1
chrX_+_166238901 0.26 ENSMUST00000112235.1
glycoprotein m6b
chr9_-_107605295 0.26 ENSMUST00000102529.3
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
chr1_+_167598384 0.25 ENSMUST00000015987.3
retinoid X receptor gamma
chr19_+_41981709 0.24 ENSMUST00000026170.1
ubiquitin domain containing 1
chr19_+_45149833 0.24 ENSMUST00000026236.9
T cell leukemia, homeobox 1

Network of associatons between targets according to the STRING database.

First level regulatory network of Ebf3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.2 9.5 GO:0030824 negative regulation of cGMP metabolic process(GO:0030824) negative regulation of cGMP biosynthetic process(GO:0030827) negative regulation of guanylate cyclase activity(GO:0031283)
0.4 1.3 GO:0033566 gamma-tubulin complex localization(GO:0033566)
0.4 2.7 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.4 1.1 GO:2000118 regulation of sodium-dependent phosphate transport(GO:2000118)
0.3 0.9 GO:0072244 metanephric glomerular epithelium development(GO:0072244)
0.3 1.2 GO:0042822 pyridoxal phosphate metabolic process(GO:0042822)
0.2 0.9 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.2 0.8 GO:1904616 regulation of actin filament binding(GO:1904529) regulation of actin binding(GO:1904616)
0.2 1.0 GO:2000157 regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) negative regulation of ubiquitin-specific protease activity(GO:2000157)
0.2 1.2 GO:0098914 positive regulation of gastric acid secretion(GO:0060454) membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.2 5.7 GO:0045780 positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.2 1.1 GO:0071486 cellular response to light intensity(GO:0071484) cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.2 0.9 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.2 0.7 GO:0003050 regulation of systemic arterial blood pressure by atrial natriuretic peptide(GO:0003050)
0.2 2.0 GO:0099638 endosome to plasma membrane protein transport(GO:0099638)
0.1 0.9 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.1 1.2 GO:0031642 negative regulation of myelination(GO:0031642)
0.1 0.4 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.1 0.5 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.1 0.9 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.1 0.8 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.1 0.6 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.1 1.2 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.1 0.4 GO:0090427 activation of meiosis(GO:0090427)
0.1 0.6 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.1 0.4 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.1 0.5 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.1 0.4 GO:0090467 interleukin-3 production(GO:0032632) L-arginine import(GO:0043091) arginine import(GO:0090467)
0.1 0.4 GO:1900377 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.1 0.4 GO:2000354 regulation of ovarian follicle development(GO:2000354)
0.1 1.3 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.1 0.2 GO:2000412 regulation of thymocyte migration(GO:2000410) positive regulation of thymocyte migration(GO:2000412)
0.1 0.2 GO:0098707 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.1 0.3 GO:0072108 positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis(GO:0072108)
0.1 1.0 GO:0021554 optic nerve development(GO:0021554)
0.1 0.4 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.1 0.8 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.1 0.6 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.1 1.0 GO:0034501 protein localization to kinetochore(GO:0034501)
0.1 1.0 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.1 0.5 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.1 0.4 GO:0032298 positive regulation of DNA-dependent DNA replication initiation(GO:0032298)
0.1 0.4 GO:0035166 post-embryonic hemopoiesis(GO:0035166)
0.1 1.3 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 0.6 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.1 0.7 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.1 1.5 GO:2000810 regulation of bicellular tight junction assembly(GO:2000810)
0.1 1.2 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.1 1.4 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.1 0.2 GO:0061642 chemoattraction of axon(GO:0061642)
0.1 0.6 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.1 1.4 GO:0021516 dorsal spinal cord development(GO:0021516)
0.1 0.7 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.1 0.3 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.1 0.4 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.1 0.3 GO:0051612 negative regulation of neurotransmitter uptake(GO:0051581) negative regulation of serotonin uptake(GO:0051612)
0.1 0.4 GO:0006362 transcription elongation from RNA polymerase I promoter(GO:0006362)
0.0 0.1 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.0 0.3 GO:0051503 adenine nucleotide transport(GO:0051503)
0.0 0.4 GO:0019896 axonal transport of mitochondrion(GO:0019896)
0.0 0.5 GO:2000980 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0 0.3 GO:0050917 sensory perception of umami taste(GO:0050917)
0.0 1.0 GO:0060539 diaphragm development(GO:0060539)
0.0 0.6 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 1.7 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.5 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 1.1 GO:0001921 positive regulation of receptor recycling(GO:0001921)
0.0 0.4 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.0 0.5 GO:0048617 foregut morphogenesis(GO:0007440) embryonic foregut morphogenesis(GO:0048617)
0.0 0.2 GO:0090273 regulation of somatostatin secretion(GO:0090273)
0.0 1.1 GO:0046685 response to arsenic-containing substance(GO:0046685)
0.0 0.2 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.0 0.2 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 0.6 GO:0051127 positive regulation of actin nucleation(GO:0051127)
0.0 0.1 GO:0045650 negative regulation of macrophage differentiation(GO:0045650)
0.0 0.1 GO:0061536 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.0 0.3 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.1 GO:0061198 fungiform papilla formation(GO:0061198)
0.0 1.7 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.0 0.1 GO:0008655 pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.0 0.3 GO:0016322 neuron remodeling(GO:0016322)
0.0 0.3 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.6 GO:0052646 alditol phosphate metabolic process(GO:0052646)
0.0 0.1 GO:0034141 positive regulation of toll-like receptor 3 signaling pathway(GO:0034141)
0.0 1.3 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 0.7 GO:0001553 luteinization(GO:0001553)
0.0 0.5 GO:0032060 bleb assembly(GO:0032060)
0.0 0.2 GO:0009946 proximal/distal axis specification(GO:0009946)
0.0 0.9 GO:0031572 G2 DNA damage checkpoint(GO:0031572)
0.0 0.1 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
0.0 1.2 GO:0060612 adipose tissue development(GO:0060612)
0.0 0.1 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.0 0.5 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 1.4 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.2 GO:0014043 negative regulation of neuron maturation(GO:0014043)
0.0 0.3 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0 0.6 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.0 0.2 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0 0.4 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.3 GO:0043981 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 0.7 GO:0000281 mitotic cytokinesis(GO:0000281)
0.0 0.1 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.0 0.5 GO:0097320 membrane tubulation(GO:0097320)
0.0 0.1 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.0 0.4 GO:0010718 positive regulation of epithelial to mesenchymal transition(GO:0010718)
0.0 0.3 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0 3.9 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.0 0.0 GO:0060060 post-embryonic retina morphogenesis in camera-type eye(GO:0060060)
0.0 0.1 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.0 0.5 GO:0010107 potassium ion import(GO:0010107)
0.0 0.1 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.2 GO:0001765 membrane raft assembly(GO:0001765)
0.0 1.0 GO:0034394 protein localization to cell surface(GO:0034394)
0.0 0.3 GO:0051451 myoblast migration(GO:0051451)
0.0 0.4 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.2 GO:0045792 negative regulation of cell size(GO:0045792)
0.0 3.5 GO:0007411 axon guidance(GO:0007411)
0.0 0.3 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.2 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.0 0.1 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.2 GO:0006968 cellular defense response(GO:0006968)
0.0 0.1 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.4 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.0 1.0 GO:0055013 cardiac muscle cell development(GO:0055013)
0.0 0.6 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.3 GO:0043486 histone exchange(GO:0043486)
0.0 1.7 GO:0050807 regulation of synapse organization(GO:0050807)
0.0 0.4 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.8 GO:0022900 electron transport chain(GO:0022900)
0.0 0.5 GO:0051290 protein heterotetramerization(GO:0051290)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 9.5 GO:0044327 dendritic spine head(GO:0044327)
0.3 1.9 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.3 0.9 GO:0005608 laminin-3 complex(GO:0005608)
0.2 0.9 GO:0008537 proteasome activator complex(GO:0008537)
0.2 0.8 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.1 0.4 GO:0044317 rod spherule(GO:0044317)
0.1 0.4 GO:0030312 external encapsulating structure(GO:0030312)
0.1 0.8 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.1 4.3 GO:0060077 inhibitory synapse(GO:0060077)
0.1 1.2 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.1 0.6 GO:1903440 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.1 1.4 GO:0008385 IkappaB kinase complex(GO:0008385)
0.1 1.2 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.1 1.2 GO:0042589 zymogen granule membrane(GO:0042589)
0.1 0.6 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 0.9 GO:0098845 postsynaptic endosome(GO:0098845)
0.1 0.5 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 0.5 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.1 1.0 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.1 0.8 GO:0031080 nuclear pore outer ring(GO:0031080)
0.1 1.1 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 0.4 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.1 1.2 GO:0070938 contractile ring(GO:0070938)
0.1 1.4 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 1.3 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.1 0.4 GO:0032437 cuticular plate(GO:0032437)
0.1 1.2 GO:0001673 male germ cell nucleus(GO:0001673)
0.1 1.3 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.6 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.4 GO:0000813 ESCRT I complex(GO:0000813)
0.0 1.0 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.4 GO:0031105 septin complex(GO:0031105)
0.0 0.5 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.5 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.9 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.4 GO:1904115 axon cytoplasm(GO:1904115)
0.0 0.2 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 0.5 GO:0030137 COPI-coated vesicle(GO:0030137)
0.0 2.2 GO:0030315 T-tubule(GO:0030315)
0.0 0.1 GO:0070552 BRISC complex(GO:0070552)
0.0 0.2 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.3 GO:0000124 SAGA complex(GO:0000124)
0.0 0.3 GO:0000145 exocyst(GO:0000145)
0.0 0.4 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.3 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.1 GO:0005869 dynactin complex(GO:0005869)
0.0 0.4 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.1 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.1 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.2 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 1.1 GO:0005811 lipid particle(GO:0005811)
0.0 1.8 GO:0030496 midbody(GO:0030496)
0.0 0.1 GO:1990584 cardiac Troponin complex(GO:1990584)
0.0 0.5 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.3 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.2 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.4 2.7 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.3 1.5 GO:0038181 bile acid receptor activity(GO:0038181)
0.3 1.2 GO:0033883 pyridoxal phosphatase activity(GO:0033883)
0.3 1.9 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.3 1.1 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.3 0.8 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.2 1.2 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.2 0.6 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.2 0.6 GO:0047522 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.2 1.3 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.2 0.2 GO:0004998 transferrin receptor activity(GO:0004998)
0.2 1.0 GO:0036435 K48-linked polyubiquitin binding(GO:0036435)
0.1 1.0 GO:0072510 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.1 0.4 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1 0.4 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.1 0.9 GO:0032051 clathrin light chain binding(GO:0032051)
0.1 3.8 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.1 0.9 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 0.3 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.1 0.5 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.1 0.6 GO:0097643 amylin receptor activity(GO:0097643)
0.1 0.4 GO:0003998 acylphosphatase activity(GO:0003998)
0.1 0.4 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.1 1.4 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.1 0.3 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.1 0.4 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.1 1.9 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 0.4 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.1 1.3 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1 0.5 GO:0004046 aminoacylase activity(GO:0004046)
0.1 0.4 GO:0004111 creatine kinase activity(GO:0004111)
0.1 1.1 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.1 7.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 0.3 GO:0005499 vitamin D binding(GO:0005499)
0.1 0.6 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.1 0.5 GO:0034711 inhibin binding(GO:0034711)
0.1 0.6 GO:0003993 acid phosphatase activity(GO:0003993)
0.1 1.6 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 0.6 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 0.9 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.9 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.3 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.6 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.4 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.1 GO:0015526 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0 5.7 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds(GO:0016810)
0.0 0.3 GO:0008527 taste receptor activity(GO:0008527)
0.0 1.6 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.3 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.3 GO:0046972 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 0.3 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.0 0.1 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.2 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.0 0.2 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.0 0.5 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 1.0 GO:0016504 peptidase activator activity(GO:0016504)
0.0 0.1 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0 0.4 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.1 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.6 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.5 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 1.3 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.5 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.5 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.1 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.2 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.6 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.4 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.3 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 2.6 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 7.1 GO:0003779 actin binding(GO:0003779)
0.0 0.8 GO:0043621 protein self-association(GO:0043621)
0.0 0.3 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.9 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.5 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.1 0.9 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.1 4.6 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 2.6 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1 1.0 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 2.0 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 1.1 ST GAQ PATHWAY G alpha q Pathway
0.0 1.2 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.6 PID FGF PATHWAY FGF signaling pathway
0.0 0.5 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 1.1 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.7 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.5 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.3 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.6 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.0 0.7 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.2 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.5 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 0.7 PID AURORA B PATHWAY Aurora B signaling
0.0 0.4 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.3 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 1.1 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.5 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 5.6 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 4.9 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.1 0.5 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.1 1.4 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1 1.2 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.1 1.1 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 3.5 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.1 0.4 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.4 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.5 REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION Genes involved in Glucagon signaling in metabolic regulation
0.0 0.3 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.8 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 1.1 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 1.2 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 3.2 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 0.7 REACTOME KINESINS Genes involved in Kinesins
0.0 0.3 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.5 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.4 REACTOME APC C CDC20 MEDIATED DEGRADATION OF CYCLIN B Genes involved in APC/C:Cdc20 mediated degradation of Cyclin B
0.0 0.7 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.4 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.6 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 1.8 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.2 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.2 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.8 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 1.0 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 1.0 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.0 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.1 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters