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12D miR HR13_24

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Results for Rad21_Smc3

Z-value: 1.32

Motif logo

Transcription factors associated with Rad21_Smc3

Gene Symbol Gene ID Gene Info
ENSMUSG00000022314.9 RAD21 cohesin complex component
ENSMUSG00000024974.10 structural maintenance of chromosomes 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Smc3mm10_v2_chr19_+_53600377_536004350.841.4e-03Click!
Rad21mm10_v2_chr15_-_51991679_519917600.812.6e-03Click!

Activity profile of Rad21_Smc3 motif

Sorted Z-values of Rad21_Smc3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_+_120649188 4.21 ENSMUST00000156722.1
RAS protein activator like 1 (GAP1 like)
chr8_-_13254154 3.17 ENSMUST00000033825.4
ADP-ribosylhydrolase like 1
chr7_+_64501687 2.96 ENSMUST00000032732.8
amyloid beta (A4) precursor protein-binding, family A, member 2
chr8_-_13254068 2.89 ENSMUST00000168498.1
ADP-ribosylhydrolase like 1
chr2_-_32353247 2.82 ENSMUST00000078352.5
ENSMUST00000113352.2
ENSMUST00000113365.1
dynamin 1
chr4_+_122995944 2.81 ENSMUST00000106252.2
v-myc myelocytomatosis viral oncogene homolog, lung carcinoma derived (avian)
chr2_-_32353283 2.80 ENSMUST00000091089.5
ENSMUST00000113350.1
dynamin 1
chr6_-_87335758 2.43 ENSMUST00000042025.9
anthrax toxin receptor 1
chr17_+_26917091 2.40 ENSMUST00000078961.4
kinesin family member C5B
chr1_+_172482199 2.38 ENSMUST00000135267.1
ENSMUST00000052629.6
ENSMUST00000111235.2
immunoglobulin superfamily, member 9
chr3_-_84155762 2.32 ENSMUST00000047368.6
meiotic nuclear divisions 1 homolog (S. cerevisiae)
chr2_-_166155272 2.15 ENSMUST00000088086.3
sulfatase 2
chr17_-_33890584 2.14 ENSMUST00000114361.2
ENSMUST00000173492.1
kinesin family member C1
chr8_-_13254096 2.09 ENSMUST00000171619.1
ADP-ribosylhydrolase like 1
chr1_+_172481788 2.08 ENSMUST00000127052.1
immunoglobulin superfamily, member 9
chr2_+_19344820 2.07 ENSMUST00000150514.1
ENSMUST00000136456.1
RIKEN cDNA 4930447M23 gene
chr9_+_111439063 1.98 ENSMUST00000111879.3
doublecortin-like kinase 3
chr17_-_33890539 1.96 ENSMUST00000173386.1
kinesin family member C1
chr1_-_191575534 1.95 ENSMUST00000027933.5
denticleless homolog (Drosophila)
chr2_-_91963507 1.93 ENSMUST00000028667.3
diacylglycerol kinase zeta
chr7_-_92874196 1.88 ENSMUST00000032877.9
RIKEN cDNA 4632434I11 gene
chr12_+_80518990 1.85 ENSMUST00000021558.6
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 16
chr4_+_63215402 1.79 ENSMUST00000036300.6
collagen, type XXVII, alpha 1
chr19_-_10869757 1.78 ENSMUST00000120524.1
ENSMUST00000025645.7
transmembrane protein 132A
chr5_+_135806859 1.71 ENSMUST00000126232.1
serine/arginine repetitive matrix 3
chr3_-_121171678 1.71 ENSMUST00000170781.1
ENSMUST00000039761.5
ENSMUST00000106467.1
ENSMUST00000106466.3
ENSMUST00000164925.2
RWD domain containing 3
chr8_+_123117354 1.64 ENSMUST00000037900.8
copine VII
chr12_-_102704896 1.63 ENSMUST00000178697.1
ENSMUST00000046518.5
inositol 1,3,4-triphosphate 5/6 kinase
chr7_+_64502090 1.61 ENSMUST00000137732.1
amyloid beta (A4) precursor protein-binding, family A, member 2
chr7_+_16891755 1.61 ENSMUST00000078182.4
guanine nucleotide binding protein (G protein), gamma 8
chr7_+_49778334 1.55 ENSMUST00000140656.1
ENSMUST00000032715.6
protein arginine N-methyltransferase 3
chr7_+_127800844 1.51 ENSMUST00000106271.1
ENSMUST00000138432.1
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
chr7_-_45434590 1.51 ENSMUST00000107771.3
ENSMUST00000141761.1
RuvB-like protein 2
chr7_-_45136231 1.49 ENSMUST00000124300.1
ENSMUST00000085377.5
ribosomal protein L13A
FMS-like tyrosine kinase 3 ligand
chr16_-_14291355 1.48 ENSMUST00000090287.3
myosin, heavy polypeptide 11, smooth muscle
chr5_-_142550965 1.47 ENSMUST00000129212.1
ENSMUST00000110785.1
ENSMUST00000063635.8
Ras association and DIL domains
chr2_+_29619692 1.45 ENSMUST00000095087.4
ENSMUST00000091146.5
ENSMUST00000102872.4
Rap guanine nucleotide exchange factor (GEF) 1
chr7_+_127800604 1.45 ENSMUST00000046863.5
ENSMUST00000106272.1
ENSMUST00000139068.1
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
chr2_-_118373347 1.44 ENSMUST00000039160.2
G protein-coupled receptor 176
chr17_-_26886175 1.43 ENSMUST00000108741.2
predicted gene, 17382
chr8_+_123407082 1.42 ENSMUST00000098324.2
melanocortin 1 receptor
chr7_+_16309577 1.39 ENSMUST00000002152.6
BCL2 binding component 3
chr11_-_70982987 1.39 ENSMUST00000078528.6
complement component 1, q subcomponent binding protein
chr14_+_8080315 1.37 ENSMUST00000023924.3
ribonuclease P 14 subunit
chr8_-_84937347 1.37 ENSMUST00000109741.2
ENSMUST00000119820.1
microtubule associated serine/threonine kinase 1
chr2_+_112239468 1.35 ENSMUST00000028554.3
lysophosphatidylcholine acyltransferase 4
chr11_-_45944910 1.35 ENSMUST00000129820.1
U7 snRNP-specific Sm-like protein LSM11
chr8_-_107425029 1.33 ENSMUST00000003946.8
NIN1/RPN12 binding protein 1 homolog (S. cerevisiae)
chr2_-_54085542 1.33 ENSMUST00000100089.2
reprimo, TP53 dependent G2 arrest mediator candidate
chr8_+_71464910 1.32 ENSMUST00000048914.6
mitochondrial ribosomal protein L34
chr2_-_73386396 1.30 ENSMUST00000112044.1
ENSMUST00000112043.1
ENSMUST00000076463.5
G protein-coupled receptor 155
chr2_-_25580099 1.29 ENSMUST00000114217.1
predicted gene 996
chr7_-_109170308 1.27 ENSMUST00000036992.7
LIM domain only 1
chr11_+_32286946 1.27 ENSMUST00000101387.3
hemoglobin, theta 1B
chr4_+_88773834 1.27 ENSMUST00000177806.1
predicted gene 13290
chr12_-_26415256 1.24 ENSMUST00000020971.6
ENSMUST00000062149.4
ring finger protein 144A
chr19_-_57360668 1.22 ENSMUST00000181921.1
RIKEN cDNA B230217O12 gene
chr2_+_65620829 1.21 ENSMUST00000028377.7
sodium channel, voltage-gated, type II, alpha 1
chr4_+_152039315 1.17 ENSMUST00000084116.6
ENSMUST00000105663.1
ENSMUST00000103197.3
nucleolar protein 9
chr17_+_27685197 1.15 ENSMUST00000097360.2
protein kinase C and casein kinase substrate in neurons 1
chr11_-_103101609 1.15 ENSMUST00000103077.1
phospholipase C, delta 3
chr4_-_45108038 1.15 ENSMUST00000107809.2
ENSMUST00000107808.2
ENSMUST00000107807.1
ENSMUST00000107810.2
translocase of outer mitochondrial membrane 5 homolog (yeast)
chr18_+_37411674 1.15 ENSMUST00000051126.2
protocadherin beta 10
chr11_+_78826575 1.14 ENSMUST00000147875.2
ENSMUST00000141321.1
LYR motif containing 9
chr7_-_127260677 1.13 ENSMUST00000035276.4
dCTP pyrophosphatase 1
chr14_-_55758458 1.11 ENSMUST00000001497.7
cell death-inducing DNA fragmentation factor, alpha subunit-like effector B
chr15_+_100469034 1.10 ENSMUST00000037001.8
LETM1 domain containing 1
chr7_+_16310412 1.10 ENSMUST00000136781.1
BCL2 binding component 3
chr1_+_118321834 1.08 ENSMUST00000027626.6
ENSMUST00000112688.3
Mki67 (FHA domain) interacting nucleolar phosphoprotein
chr7_+_120842824 1.08 ENSMUST00000047875.8
eukaryotic elongation factor-2 kinase
chrX_-_102189371 1.07 ENSMUST00000033683.7
ribosomal protein S4, X-linked
chr2_-_65567505 1.06 ENSMUST00000100069.2
sodium channel, voltage-gated, type III, alpha
chr6_+_29279587 1.05 ENSMUST00000167131.1
family with sequence similarity 71, member F2
chr18_-_49755548 1.05 ENSMUST00000163590.1
ENSMUST00000025383.8
DTW domain containing 2
chr7_-_46710642 1.04 ENSMUST00000143082.1
serum amyloid A-like 1
chr2_-_26640230 1.04 ENSMUST00000181621.1
ENSMUST00000180659.1
small nucleolar RNA host gene (non-protein coding) 7
chr2_-_117342709 1.03 ENSMUST00000173541.1
ENSMUST00000172901.1
ENSMUST00000173252.1
RAS guanyl releasing protein 1
chr1_-_38129618 1.03 ENSMUST00000027251.6
REV1 homolog (S. cerevisiae)
chr19_-_10240689 1.02 ENSMUST00000088013.5
myelin regulatory factor
chr10_-_80577285 1.00 ENSMUST00000038558.8
Kruppel-like factor 16
chr12_-_101028983 1.00 ENSMUST00000068411.3
ENSMUST00000085096.3
coiled-coil domain containing 88C
chr2_-_65567465 0.99 ENSMUST00000066432.5
sodium channel, voltage-gated, type III, alpha
chr15_-_102350692 0.98 ENSMUST00000041208.7
achalasia, adrenocortical insufficiency, alacrimia
chr4_-_131838231 0.97 ENSMUST00000030741.2
ENSMUST00000105987.2
protein tyrosine phosphatase, receptor type, U
chr11_+_78178105 0.96 ENSMUST00000147819.1
TLC domain containing 1
chr4_-_137796350 0.96 ENSMUST00000030551.4
alkaline phosphatase, liver/bone/kidney
chr11_-_75169519 0.96 ENSMUST00000055619.4
hypermethylated in cancer 1
chr17_+_34135182 0.94 ENSMUST00000042121.9
histocompatibility 2, class II, locus DMa
chr11_-_116138862 0.94 ENSMUST00000106439.1
mitochondrial ribosomal protein L38
chr5_+_91517615 0.93 ENSMUST00000040576.9
prostate androgen-regulated mucin-like protein 1
chr6_+_85915787 0.93 ENSMUST00000149026.1
Tp53rk binding protein
chr9_+_111311674 0.92 ENSMUST00000078626.3
tetratricopeptide repeat and ankyrin repeat containing 1
chr13_-_54055650 0.91 ENSMUST00000021932.5
dopamine receptor D1A
chr15_+_26309039 0.90 ENSMUST00000140840.1
ENSMUST00000152841.1
membrane-associated ring finger (C3HC4) 11
chr2_-_166155624 0.86 ENSMUST00000109249.2
sulfatase 2
chr2_-_122369130 0.86 ENSMUST00000151130.1
ENSMUST00000125826.1
Src homology 2 domain containing F
chr13_-_43304153 0.86 ENSMUST00000055341.5
glucose-fructose oxidoreductase domain containing 1
chr4_-_116167591 0.85 ENSMUST00000030465.3
ENSMUST00000143426.1
tetraspanin 1
chr17_+_45563928 0.85 ENSMUST00000041353.6
solute carrier family 35, member B2
chr2_-_178407583 0.82 ENSMUST00000081134.3
synaptonemal complex protein 2
chr5_+_107900859 0.81 ENSMUST00000153590.1
ribosomal protein L5
chr4_-_132345686 0.80 ENSMUST00000030726.6
regulator of chromosome condensation 1
chr4_-_132345715 0.79 ENSMUST00000084250.4
regulator of chromosome condensation 1
chr4_+_151933691 0.79 ENSMUST00000062904.4
DnaJ (Hsp40) homolog, subfamily C, member 11
chr14_-_55106547 0.78 ENSMUST00000036041.8
adaptor protein complex AP-1, gamma 2 subunit
chr19_-_38819156 0.75 ENSMUST00000025963.7
nucleolar complex associated 3 homolog (S. cerevisiae)
chrX_+_159532674 0.75 ENSMUST00000057180.6
RIKEN cDNA A830080D01 gene
chr17_+_56613392 0.75 ENSMUST00000080492.5
ribosomal protein L36
chr9_-_108452377 0.73 ENSMUST00000035232.7
kelch domain containing 8B
chr7_-_141437829 0.73 ENSMUST00000019226.7
solute carrier family 25 (mitochondrial carrier, glutamate), member 22
chr5_-_137741601 0.73 ENSMUST00000119498.1
ENSMUST00000061789.7
neuronal tyrosine-phosphorylated phosphoinositide 3-kinase adaptor 1
chr3_-_104777483 0.73 ENSMUST00000139783.1
family with sequence similarity 19, member A3
chr10_-_31445921 0.71 ENSMUST00000000305.5
tumor protein D52-like 1
chr10_-_127030789 0.71 ENSMUST00000120547.1
ENSMUST00000152054.1
Ts translation elongation factor, mitochondrial
chr5_-_137741102 0.71 ENSMUST00000149512.1
neuronal tyrosine-phosphorylated phosphoinositide 3-kinase adaptor 1
chr5_+_107900502 0.70 ENSMUST00000082223.6
ribosomal protein L5
chr11_-_115322025 0.70 ENSMUST00000103037.4
Usher syndrome 1G
chr19_-_12501996 0.69 ENSMUST00000045521.7
deltex 4 homolog (Drosophila)
chr18_+_42511496 0.69 ENSMUST00000025375.7
transcription elongation regulator 1 (CA150)
chrX_-_150459128 0.69 ENSMUST00000173996.1
transmembrane protein 29
chr11_-_94549165 0.68 ENSMUST00000040487.3
radical S-adenosyl methionine domain containing 1
chr11_+_114668524 0.67 ENSMUST00000106602.3
ENSMUST00000077915.3
ENSMUST00000106599.1
ENSMUST00000082092.4
ribosomal protein L38
chr4_+_140701466 0.67 ENSMUST00000038893.5
ENSMUST00000138808.1
regulator of chromosome condensation 2
chr7_-_141437587 0.67 ENSMUST00000172654.1
ENSMUST00000106006.1
solute carrier family 25 (mitochondrial carrier, glutamate), member 22
chr10_+_79793553 0.67 ENSMUST00000046945.6
ENSMUST00000105379.2
paralemmin
chr19_+_44989073 0.66 ENSMUST00000026225.8
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chr2_-_66410064 0.66 ENSMUST00000112366.1
sodium channel, voltage-gated, type I, alpha
chr11_+_32300069 0.65 ENSMUST00000020535.1
hemoglobin, theta 1A
chr18_+_4921662 0.65 ENSMUST00000143254.1
supervillin
chr9_-_60522017 0.65 ENSMUST00000140824.1
thrombospondin, type I, domain containing 4
chr14_+_73510014 0.64 ENSMUST00000022705.5
mediator of RNA polymerase II transcription, subunit 4 homolog (yeast)
chr17_-_25433775 0.64 ENSMUST00000159610.1
ENSMUST00000159048.1
ENSMUST00000078496.5
calcium channel, voltage-dependent, T type, alpha 1H subunit
chr7_+_120917744 0.64 ENSMUST00000033173.7
ENSMUST00000106483.2
polymerase (RNA) III (DNA directed) polypeptide E
chr1_+_150392794 0.63 ENSMUST00000124973.2
translocated promoter region
chr15_-_76817970 0.63 ENSMUST00000175843.1
ENSMUST00000177026.1
ENSMUST00000176736.1
ENSMUST00000036176.8
ENSMUST00000176219.1
ENSMUST00000077821.3
Rho GTPase activating protein 39
chr5_-_135078224 0.63 ENSMUST00000067935.4
ENSMUST00000076203.2
vacuolar protein sorting 37D (yeast)
chr10_-_128409632 0.62 ENSMUST00000172348.1
ENSMUST00000166608.1
ENSMUST00000164199.1
ENSMUST00000171370.1
ENSMUST00000026439.7
nucleic acid binding protein 2
chr10_-_127030813 0.61 ENSMUST00000040560.4
Ts translation elongation factor, mitochondrial
chr16_-_10785525 0.61 ENSMUST00000038099.4
suppressor of cytokine signaling 1
chr11_-_3914664 0.60 ENSMUST00000109995.1
ENSMUST00000051207.1
solute carrier family 35, member E4
chr6_+_124570294 0.60 ENSMUST00000184647.1
complement component 1, r subcomponent B
chr12_+_33429605 0.60 ENSMUST00000020877.7
TWIST neighbor
chrX_+_159532655 0.60 ENSMUST00000112464.1
RIKEN cDNA A830080D01 gene
chr9_-_44735189 0.59 ENSMUST00000034611.8
pleckstrin homology-like domain, family B, member 1
chr9_+_44773191 0.59 ENSMUST00000147559.1
intraflagellar transport 46
chr19_-_28963863 0.59 ENSMUST00000161813.1
RIKEN cDNA 4430402I18 gene
chr5_+_115559505 0.58 ENSMUST00000156359.1
ENSMUST00000152976.1
ribosomal protein, large, P0
chr7_-_120670256 0.58 ENSMUST00000033178.2
PDZ domain containing 9
chr4_-_44073016 0.58 ENSMUST00000128439.1
ENSMUST00000140724.2
glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
chr18_+_73863672 0.58 ENSMUST00000134847.1
maestro
chr14_-_24486994 0.58 ENSMUST00000026322.7
polymerase (RNA) III (DNA directed) polypeptide A
chr8_-_25994103 0.58 ENSMUST00000061850.3
protein-O-mannose kinase
chr13_-_55536504 0.57 ENSMUST00000021956.8
DEAD (Asp-Glu-Ala-Asp) box polypeptide 41
chr8_-_123515455 0.57 ENSMUST00000176286.1
ENSMUST00000169210.1
ENSMUST00000074879.5
ENSMUST00000066198.7
ENSMUST00000176155.1
dysbindin (dystrobrevin binding protein 1) domain containing 1
chr4_+_88776922 0.57 ENSMUST00000179158.1
predicted gene 13289
chr14_+_45329815 0.57 ENSMUST00000022380.7
proteasome (prosome, macropain) 26S subunit, ATPase, 6
chr5_-_143315360 0.57 ENSMUST00000046418.2
RIKEN cDNA E130309D02 gene
chr17_+_3114957 0.57 ENSMUST00000076734.6
SR-related CTD-associated factor 8
chr5_+_115559467 0.56 ENSMUST00000086519.5
ribosomal protein, large, P0
chrX_+_100494291 0.56 ENSMUST00000033570.5
immunoglobulin (CD79A) binding protein 1
chr5_+_64160207 0.56 ENSMUST00000101195.2
TBC1 domain family, member 1
chr10_+_121033960 0.55 ENSMUST00000020439.4
ENSMUST00000175867.1
Wnt inhibitory factor 1
chr6_+_124512615 0.55 ENSMUST00000068593.7
complement component 1, r subcomponent A
chr2_-_114175274 0.55 ENSMUST00000102543.4
aquarius
chr16_+_18052860 0.55 ENSMUST00000143343.1
DiGeorge syndrome critical region gene 6
chr9_-_86464944 0.55 ENSMUST00000034986.7
ubiquitin-conjugating enzyme E2C binding protein
chr16_+_16302955 0.55 ENSMUST00000159962.1
ENSMUST00000059955.8
tyrosyl-tRNA synthetase 2 (mitochondrial)
chr10_+_3973086 0.55 ENSMUST00000117291.1
ENSMUST00000120585.1
ENSMUST00000043735.7
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
chr16_+_31428745 0.54 ENSMUST00000115227.3
3-hydroxybutyrate dehydrogenase, type 1
chr6_+_85915709 0.54 ENSMUST00000113751.1
ENSMUST00000113753.1
ENSMUST00000113752.1
ENSMUST00000067137.7
Tp53rk binding protein
chr3_-_89160155 0.54 ENSMUST00000029686.3
hyperpolarization-activated, cyclic nucleotide-gated K+ 3
chr3_+_122245557 0.53 ENSMUST00000029769.7
glutamate-cysteine ligase, modifier subunit
chr4_+_149485215 0.53 ENSMUST00000124413.1
ENSMUST00000141293.1
leucine zipper and CTNNBIP1 domain containing
chr14_-_70167973 0.53 ENSMUST00000125300.1
PDZ and LIM domain 2
chr5_+_76809964 0.53 ENSMUST00000120818.1
RIKEN cDNA C530008M17 gene
chr7_-_127026479 0.52 ENSMUST00000032916.4
MYC-associated zinc finger protein (purine-binding transcription factor)
chr13_-_35027077 0.52 ENSMUST00000170538.1
ENSMUST00000163280.1
enoyl-Coenzyme A delta isomerase 2
chr19_-_42431778 0.52 ENSMUST00000048630.6
cartilage acidic protein 1
chr12_+_113156403 0.50 ENSMUST00000049271.8
RIKEN cDNA 4930427A07 gene
chr9_-_86464900 0.49 ENSMUST00000121189.1
ubiquitin-conjugating enzyme E2C binding protein
chr2_+_170511418 0.49 ENSMUST00000136839.1
ENSMUST00000109148.1
ENSMUST00000170167.1
prefoldin 4
chr19_-_24280551 0.49 ENSMUST00000081333.4
frataxin
chr14_+_57999305 0.49 ENSMUST00000180534.1
RIKEN cDNA 3110083C13 gene
chr2_-_153015331 0.48 ENSMUST00000028972.8
p53 and DNA damage regulated 1
chr7_-_45136056 0.48 ENSMUST00000130628.1
FMS-like tyrosine kinase 3 ligand
chrX_+_20059535 0.48 ENSMUST00000044138.7
carbohydrate (N-acetylglucosamino) sulfotransferase 7
chr14_+_33319703 0.47 ENSMUST00000111955.1
Rho GTPase activating protein 22
chrX_+_137049586 0.47 ENSMUST00000047852.7
family with sequence similarity 199, X-linked
chr10_-_14544972 0.47 ENSMUST00000041168.4
G protein-coupled receptor 126
chr2_+_167538192 0.47 ENSMUST00000052631.7
snail homolog 1 (Drosophila)
chr2_+_38931975 0.47 ENSMUST00000057279.5
olfactomedin-like 2A
chr4_-_44072578 0.46 ENSMUST00000173383.1
glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
chr2_-_155514796 0.46 ENSMUST00000029131.4
gamma-glutamyltransferase 7
chr4_+_149485260 0.46 ENSMUST00000030842.7
leucine zipper and CTNNBIP1 domain containing
chr2_+_112379204 0.46 ENSMUST00000028552.3
katanin p80 subunit B like 1
chr2_-_12301914 0.45 ENSMUST00000028106.4
integrin alpha 8
chr18_+_4920509 0.44 ENSMUST00000126977.1
supervillin
chr3_+_67430096 0.44 ENSMUST00000077271.6
ENSMUST00000161009.1
G elongation factor, mitochondrial 1
chr17_-_56935388 0.44 ENSMUST00000025053.8
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1
chr9_-_45906369 0.44 ENSMUST00000161187.1
ring finger protein 214

Network of associatons between targets according to the STRING database.

First level regulatory network of Rad21_Smc3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.1 GO:0072382 minus-end-directed vesicle transport along microtubule(GO:0072382)
1.2 8.2 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.8 5.6 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.8 3.0 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.6 2.5 GO:1900739 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.6 1.7 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039) regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
0.5 1.5 GO:1903632 positive regulation of aminoacyl-tRNA ligase activity(GO:1903632)
0.5 1.5 GO:0071733 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.5 1.4 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.4 1.8 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.4 1.3 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.4 2.1 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290)
0.4 2.0 GO:0046684 response to pyrethroid(GO:0046684)
0.4 2.4 GO:1903054 negative regulation of extracellular matrix organization(GO:1903054)
0.4 1.2 GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448)
0.4 1.5 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.3 3.0 GO:0035754 B cell chemotaxis(GO:0035754)
0.3 1.8 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.3 0.9 GO:0031990 RNA import into nucleus(GO:0006404) mRNA export from nucleus in response to heat stress(GO:0031990) negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
0.3 1.1 GO:0006244 pyrimidine nucleotide catabolic process(GO:0006244) pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
0.3 2.8 GO:0045607 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.2 0.5 GO:0019230 proprioception(GO:0019230)
0.2 3.0 GO:0019985 translesion synthesis(GO:0019985)
0.2 0.7 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.2 0.9 GO:0002636 positive regulation of germinal center formation(GO:0002636)
0.2 3.1 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.2 0.5 GO:0061314 Notch signaling involved in heart development(GO:0061314)
0.2 4.2 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.1 0.7 GO:1903978 regulation of microglial cell activation(GO:1903978)
0.1 1.4 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.1 1.3 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.1 0.4 GO:0045204 MAPK export from nucleus(GO:0045204)
0.1 0.8 GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987)
0.1 0.4 GO:1902162 regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162)
0.1 0.4 GO:0098917 retrograde trans-synaptic signaling(GO:0098917)
0.1 1.0 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.1 0.8 GO:0051409 response to nitrosative stress(GO:0051409)
0.1 0.4 GO:2000721 positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.1 1.7 GO:0038180 nerve growth factor signaling pathway(GO:0038180)
0.1 1.5 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.1 0.3 GO:1901420 negative regulation of response to alcohol(GO:1901420)
0.1 0.4 GO:1900864 tRNA wobble position uridine thiolation(GO:0002143) mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.1 0.3 GO:0032377 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.1 1.6 GO:0019236 response to pheromone(GO:0019236)
0.1 0.8 GO:0051503 adenine nucleotide transport(GO:0051503)
0.1 1.4 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.1 0.4 GO:0042494 detection of bacterial lipoprotein(GO:0042494)
0.1 0.2 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
0.1 0.3 GO:0051834 CD4-positive, CD25-positive, alpha-beta regulatory T cell lineage commitment(GO:0002362) evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834) positive regulation of mononuclear cell migration(GO:0071677) negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.1 0.5 GO:0009256 10-formyltetrahydrofolate metabolic process(GO:0009256) tetrahydrofolate biosynthetic process(GO:0046654)
0.1 0.6 GO:0045591 positive regulation of regulatory T cell differentiation(GO:0045591)
0.1 1.0 GO:2000400 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.1 0.2 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.1 1.5 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.1 0.6 GO:0034650 cortisol metabolic process(GO:0034650) cortisol biosynthetic process(GO:0034651)
0.1 0.7 GO:0050957 equilibrioception(GO:0050957)
0.1 0.5 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.1 0.2 GO:0046061 dATP catabolic process(GO:0046061)
0.1 0.7 GO:0048318 axial mesoderm development(GO:0048318)
0.1 0.5 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.1 0.4 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.1 0.1 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.1 0.2 GO:0036090 cleavage furrow ingression(GO:0036090)
0.1 0.9 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.1 1.5 GO:0000469 cleavage involved in rRNA processing(GO:0000469)
0.1 1.0 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.1 0.3 GO:0044268 multicellular organismal protein metabolic process(GO:0044268)
0.1 0.2 GO:0051325 interphase(GO:0051325) mitotic interphase(GO:0051329)
0.1 0.4 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.1 0.6 GO:0090261 positive regulation of inclusion body assembly(GO:0090261)
0.1 1.0 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.1 0.7 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1 0.2 GO:0044313 protein K6-linked deubiquitination(GO:0044313) protein K27-linked deubiquitination(GO:1990167)
0.1 0.2 GO:0048069 eye pigmentation(GO:0048069)
0.1 0.3 GO:0034628 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.1 0.3 GO:0035356 cellular triglyceride homeostasis(GO:0035356)
0.1 0.3 GO:1903679 regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690)
0.1 0.6 GO:1904259 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.1 0.5 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.1 0.3 GO:0010940 positive regulation of necrotic cell death(GO:0010940)
0.1 0.2 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.1 0.3 GO:0071169 establishment of protein localization to chromatin(GO:0071169)
0.1 0.2 GO:0051892 negative regulation of cardioblast differentiation(GO:0051892)
0.0 0.2 GO:0036089 cleavage furrow formation(GO:0036089)
0.0 1.4 GO:0015813 L-glutamate transport(GO:0015813)
0.0 2.1 GO:0030818 negative regulation of cAMP biosynthetic process(GO:0030818)
0.0 0.5 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.3 GO:0060368 negative regulation of low-density lipoprotein particle clearance(GO:0010989) negative regulation of Golgi to plasma membrane protein transport(GO:0042997) regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060368) negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.0 0.4 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 1.2 GO:0097320 membrane tubulation(GO:0097320)
0.0 0.2 GO:0032053 ciliary basal body organization(GO:0032053)
0.0 0.1 GO:1903002 positive regulation of low-density lipoprotein particle receptor catabolic process(GO:0032805) negative regulation of presynaptic membrane organization(GO:1901630) regulation of lipid transport across blood brain barrier(GO:1903000) positive regulation of lipid transport across blood brain barrier(GO:1903002)
0.0 1.1 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.0 0.4 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 1.0 GO:0001539 cilium or flagellum-dependent cell motility(GO:0001539) cilium-dependent cell motility(GO:0060285)
0.0 0.5 GO:1900121 negative regulation of receptor binding(GO:1900121)
0.0 0.3 GO:0035280 miRNA loading onto RISC involved in gene silencing by miRNA(GO:0035280)
0.0 0.6 GO:0070200 establishment of protein localization to telomere(GO:0070200)
0.0 0.5 GO:0006751 glutathione catabolic process(GO:0006751)
0.0 2.1 GO:0051290 protein heterotetramerization(GO:0051290)
0.0 0.2 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0 0.2 GO:2001015 negative regulation of skeletal muscle cell differentiation(GO:2001015)
0.0 0.1 GO:0021759 globus pallidus development(GO:0021759)
0.0 0.4 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.0 3.7 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.2 GO:0032364 oxygen homeostasis(GO:0032364)
0.0 1.7 GO:0035825 reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.0 1.1 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.0 1.2 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.0 0.3 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 0.1 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.2 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.0 0.4 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.0 0.0 GO:0032202 telomere assembly(GO:0032202)
0.0 0.2 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.2 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 1.2 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.1 GO:0035511 oxidative DNA demethylation(GO:0035511)
0.0 0.6 GO:0046835 carbohydrate phosphorylation(GO:0046835)
0.0 0.3 GO:0070236 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.1 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0 1.0 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)
0.0 0.1 GO:0072717 cellular response to actinomycin D(GO:0072717)
0.0 0.2 GO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.0 0.1 GO:0002019 regulation of renal output by angiotensin(GO:0002019)
0.0 0.9 GO:0051973 positive regulation of telomerase activity(GO:0051973)
0.0 0.2 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.0 0.1 GO:0014022 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.0 0.3 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.5 GO:0046855 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067) inositol phosphate dephosphorylation(GO:0046855)
0.0 2.0 GO:1900181 negative regulation of protein localization to nucleus(GO:1900181)
0.0 0.0 GO:0034227 tRNA thio-modification(GO:0034227)
0.0 0.1 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313)
0.0 1.1 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.0 0.7 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.8 GO:0046677 response to antibiotic(GO:0046677)
0.0 0.2 GO:0010891 negative regulation of sequestering of triglyceride(GO:0010891)
0.0 0.1 GO:0006083 acetate metabolic process(GO:0006083) short-chain fatty acid biosynthetic process(GO:0051790)
0.0 1.0 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 0.3 GO:0044458 motile cilium assembly(GO:0044458)
0.0 0.1 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.0 0.4 GO:0070266 necroptotic process(GO:0070266)
0.0 0.4 GO:0031297 replication fork processing(GO:0031297)
0.0 0.0 GO:0019676 ammonia assimilation cycle(GO:0019676) arginine biosynthetic process via ornithine(GO:0042450)
0.0 0.3 GO:0032026 response to magnesium ion(GO:0032026)
0.0 1.8 GO:0008033 tRNA processing(GO:0008033)
0.0 0.2 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.1 GO:0071285 cellular response to lithium ion(GO:0071285)
0.0 0.3 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 2.1 GO:0006626 protein targeting to mitochondrion(GO:0006626)
0.0 0.2 GO:0009303 rRNA transcription(GO:0009303)
0.0 0.1 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.8 GO:0034394 protein localization to cell surface(GO:0034394)
0.0 1.0 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.1 GO:0071816 tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0 0.1 GO:0015670 carbon dioxide transport(GO:0015670)
0.0 0.3 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.7 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 0.3 GO:0007625 grooming behavior(GO:0007625)
0.0 0.9 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 0.6 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.2 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.2 GO:0007289 spermatid nucleus differentiation(GO:0007289)
0.0 0.6 GO:0030521 androgen receptor signaling pathway(GO:0030521)
0.0 0.1 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.2 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 1.6 GO:0050821 protein stabilization(GO:0050821)
0.0 0.2 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 0.3 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.1 GO:2000525 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.0 1.2 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 0.4 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.2 GO:0035428 hexose transmembrane transport(GO:0035428)
0.0 0.1 GO:0042795 snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.0 2.9 GO:0035264 multicellular organism growth(GO:0035264)
0.0 0.4 GO:0000002 mitochondrial genome maintenance(GO:0000002)
0.0 0.2 GO:0071480 cellular response to gamma radiation(GO:0071480)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.5 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.3 6.0 GO:0043196 varicosity(GO:0043196)
0.3 2.0 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.3 1.3 GO:0005683 U7 snRNP(GO:0005683)
0.3 0.8 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.2 1.4 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.2 4.2 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.2 1.5 GO:0097452 GAIT complex(GO:0097452)
0.2 1.5 GO:0097255 R2TP complex(GO:0097255)
0.2 1.5 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.2 4.1 GO:0031616 spindle pole centrosome(GO:0031616)
0.2 2.4 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 2.7 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 0.9 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.1 1.8 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 0.5 GO:0044316 cone cell pedicle(GO:0044316)
0.1 1.3 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 1.1 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.1 0.3 GO:0034679 integrin alpha9-beta1 complex(GO:0034679)
0.1 0.6 GO:0070876 SOSS complex(GO:0070876)
0.1 0.4 GO:0035101 FACT complex(GO:0035101)
0.1 4.5 GO:0060077 inhibitory synapse(GO:0060077)
0.1 1.1 GO:0032591 dendritic spine membrane(GO:0032591)
0.1 0.6 GO:0070847 core mediator complex(GO:0070847)
0.1 1.5 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.1 1.0 GO:0016272 prefoldin complex(GO:0016272)
0.1 0.5 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.1 0.9 GO:0030681 ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.1 0.9 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 0.6 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1 0.6 GO:0000813 ESCRT I complex(GO:0000813)
0.1 1.5 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 0.4 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.1 0.7 GO:1990023 mitotic spindle midzone(GO:1990023)
0.1 0.6 GO:0031595 nuclear proteasome complex(GO:0031595)
0.1 0.5 GO:0005687 U4 snRNP(GO:0005687)
0.1 3.0 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.2 GO:0097361 CIA complex(GO:0097361)
0.0 0.8 GO:0005838 proteasome regulatory particle(GO:0005838)
0.0 3.2 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.3 GO:0031933 telomeric heterochromatin(GO:0031933)
0.0 0.1 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 0.3 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.1 GO:0016939 kinesin II complex(GO:0016939)
0.0 0.6 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.6 GO:0045180 basal cortex(GO:0045180)
0.0 2.0 GO:0005871 kinesin complex(GO:0005871)
0.0 0.5 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.9 GO:0030137 COPI-coated vesicle(GO:0030137)
0.0 0.6 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.0 0.3 GO:0070578 RISC-loading complex(GO:0070578)
0.0 0.2 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.3 GO:0034719 SMN-Sm protein complex(GO:0034719)
0.0 0.2 GO:0071203 WASH complex(GO:0071203)
0.0 0.8 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.7 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 0.2 GO:0031414 N-terminal protein acetyltransferase complex(GO:0031414)
0.0 0.1 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.0 0.3 GO:0061700 GATOR2 complex(GO:0061700)
0.0 2.5 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 1.1 GO:0043034 costamere(GO:0043034)
0.0 0.3 GO:1990635 proximal dendrite(GO:1990635)
0.0 1.1 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.2 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.4 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.1 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.1 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 1.6 GO:0005840 ribosome(GO:0005840)
0.0 0.8 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 3.2 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 0.2 GO:0070938 contractile ring(GO:0070938)
0.0 2.0 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.0 0.7 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.2 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.1 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.0 3.4 GO:0008021 synaptic vesicle(GO:0008021)
0.0 0.6 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.1 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.2 GO:0031082 BLOC complex(GO:0031082)
0.0 0.2 GO:0032433 filopodium tip(GO:0032433)
0.0 0.2 GO:0016589 NURF complex(GO:0016589)
0.0 1.0 GO:0005643 nuclear pore(GO:0005643)
0.0 0.2 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.1 GO:1990909 Wnt signalosome(GO:1990909)
0.0 0.1 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.2 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 8.2 GO:0003875 ADP-ribosylarginine hydrolase activity(GO:0003875)
0.7 0.7 GO:0031750 D3 dopamine receptor binding(GO:0031750)
0.6 3.0 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.5 1.6 GO:0051765 inositol tetrakisphosphate kinase activity(GO:0051765)
0.5 5.2 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.5 1.4 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.4 1.3 GO:0071209 U7 snRNA binding(GO:0071209)
0.4 1.2 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.4 1.1 GO:0004686 elongation factor-2 kinase activity(GO:0004686)
0.3 1.4 GO:0030984 kininogen binding(GO:0030984)
0.3 3.0 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.3 1.5 GO:0008761 UDP-N-acetylglucosamine 2-epimerase activity(GO:0008761)
0.3 0.8 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.3 1.6 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087) sulfate binding(GO:0043199)
0.3 0.8 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.3 1.5 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.2 0.9 GO:0008802 betaine-aldehyde dehydrogenase activity(GO:0008802)
0.2 3.1 GO:0005132 type I interferon receptor binding(GO:0005132)
0.2 1.5 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.2 1.4 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.2 1.5 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.2 1.2 GO:0051731 polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.2 0.7 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.2 0.6 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.2 0.5 GO:0003963 RNA-3'-phosphate cyclase activity(GO:0003963)
0.2 0.5 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.2 4.1 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.1 1.9 GO:0001727 lipid kinase activity(GO:0001727)
0.1 1.0 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.1 0.5 GO:0004488 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
0.1 1.4 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.1 4.5 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.1 2.7 GO:0031402 sodium ion binding(GO:0031402)
0.1 1.4 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.1 0.5 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.1 0.5 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) chondroitin sulfotransferase activity(GO:0034481)
0.1 0.5 GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.1 0.6 GO:0001054 RNA polymerase I activity(GO:0001054)
0.1 0.2 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.1 0.6 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.1 0.9 GO:0004526 ribonuclease P activity(GO:0004526)
0.1 0.2 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.1 1.8 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 0.3 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 4.2 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 0.2 GO:0000700 mismatch base pair DNA N-glycosylase activity(GO:0000700)
0.1 0.5 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 1.2 GO:0001056 RNA polymerase III activity(GO:0001056)
0.1 0.5 GO:1990446 U1 snRNP binding(GO:1990446)
0.1 0.3 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.1 0.3 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 0.3 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.1 0.3 GO:0008097 5S rRNA binding(GO:0008097)
0.1 0.5 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 1.0 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.1 GO:0051747 cytosine C-5 DNA demethylase activity(GO:0051747)
0.0 0.7 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0 0.5 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.6 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 1.0 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.5 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.5 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 0.3 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 7.8 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.2 GO:0032407 exodeoxyribonuclease III activity(GO:0008853) MutLalpha complex binding(GO:0032405) MutSalpha complex binding(GO:0032407)
0.0 0.9 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.0 0.3 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 2.2 GO:0044390 ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0 1.0 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.1 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.4 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.2 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 1.8 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.3 GO:0043426 MRF binding(GO:0043426)
0.0 0.3 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 1.2 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.2 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.0 1.6 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.2 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.0 0.4 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.2 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.0 2.0 GO:0003777 microtubule motor activity(GO:0003777)
0.0 1.4 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 1.1 GO:0043175 RNA polymerase core enzyme binding(GO:0043175)
0.0 0.4 GO:0070034 telomerase RNA binding(GO:0070034)
0.0 0.1 GO:0003692 left-handed Z-DNA binding(GO:0003692)
0.0 0.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.8 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.2 GO:0000150 recombinase activity(GO:0000150)
0.0 0.2 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0 0.1 GO:0009374 biotin binding(GO:0009374)
0.0 0.5 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 1.6 GO:0005518 collagen binding(GO:0005518)
0.0 0.2 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.6 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 1.0 GO:0003684 damaged DNA binding(GO:0003684)
0.0 0.1 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.6 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.0 0.3 GO:0034062 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.3 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 1.8 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.2 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 1.9 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.6 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 0.3 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.5 GO:0003954 NADH dehydrogenase activity(GO:0003954)
0.0 0.1 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.0 0.2 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 1.0 GO:0003724 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.0 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.7 GO:0030507 spectrin binding(GO:0030507)
0.0 0.3 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.3 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.2 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.6 GO:0000049 tRNA binding(GO:0000049)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.4 PID RAS PATHWAY Regulation of Ras family activation
0.1 4.9 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.1 2.4 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 1.0 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 1.4 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 1.0 PID MYC PATHWAY C-MYC pathway
0.0 3.5 PID P73PATHWAY p73 transcription factor network
0.0 1.9 NABA COLLAGENS Genes encoding collagen proteins
0.0 1.1 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.6 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 0.3 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 1.5 PID P53 REGULATION PATHWAY p53 pathway
0.0 1.5 PID E2F PATHWAY E2F transcription factor network
0.0 1.1 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.7 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 1.8 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 1.2 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 1.1 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.4 PID NCADHERIN PATHWAY N-cadherin signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 5.6 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.3 3.0 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.2 4.2 REACTOME KINESINS Genes involved in Kinesins
0.2 1.8 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.1 0.4 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.1 2.5 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 0.6 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.1 1.7 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.1 1.2 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.1 1.5 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.1 1.4 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.1 7.3 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.1 1.9 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.1 1.4 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.1 1.9 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 1.6 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.0 0.6 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 2.0 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.0 1.1 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.5 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.5 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 1.2 REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING Genes involved in Integrin alphaIIb beta3 signaling
0.0 1.6 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 1.2 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 2.1 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 2.0 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 1.7 REACTOME LATE PHASE OF HIV LIFE CYCLE Genes involved in Late Phase of HIV Life Cycle
0.0 0.5 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.5 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.5 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.3 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.7 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 1.4 REACTOME DNA REPAIR Genes involved in DNA Repair
0.0 1.8 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.1 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.6 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.3 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.3 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.3 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.6 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.3 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.5 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.0 0.3 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.7 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.1 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.3 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.4 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.1 REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE Genes involved in p53-Dependent G1 DNA Damage Response