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12D miR HR13_24

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Results for Tbx21

Z-value: 0.73

Motif logo

Transcription factors associated with Tbx21

Gene Symbol Gene ID Gene Info
ENSMUSG00000001444.2 T-box 21

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Tbx21mm10_v2_chr11_-_97115327_971153320.605.3e-02Click!

Activity profile of Tbx21 motif

Sorted Z-values of Tbx21 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr16_-_44333135 1.92 ENSMUST00000047446.6
SID1 transmembrane family, member 1
chr16_-_44332925 1.85 ENSMUST00000136381.1
SID1 transmembrane family, member 1
chr14_+_64588112 1.81 ENSMUST00000181808.1
RIKEN cDNA A930011O12 gene
chr8_-_13254154 1.62 ENSMUST00000033825.4
ADP-ribosylhydrolase like 1
chr3_+_14863495 1.52 ENSMUST00000029076.4
carbonic anhydrase 3
chr3_-_89322883 1.47 ENSMUST00000029673.5
ephrin A3
chr8_-_13254068 1.32 ENSMUST00000168498.1
ADP-ribosylhydrolase like 1
chr7_-_127042420 1.25 ENSMUST00000032915.6
kinesin family member 22
chr8_-_13254096 1.03 ENSMUST00000171619.1
ADP-ribosylhydrolase like 1
chr15_+_99074968 0.96 ENSMUST00000039665.6
trophinin associated protein
chr17_+_35861318 0.94 ENSMUST00000074259.8
ENSMUST00000174873.1
nurim (nuclear envelope membrane protein)
chr6_+_129397297 0.91 ENSMUST00000032262.7
C-type lectin domain family 1, member b
chr4_+_154869585 0.89 ENSMUST00000079269.7
ENSMUST00000163732.1
ENSMUST00000080559.6
membrane metallo-endopeptidase-like 1
chr9_+_55326913 0.88 ENSMUST00000085754.3
ENSMUST00000034862.4
expressed sequence AI118078
chr3_-_94436574 0.81 ENSMUST00000029787.4
ornithine decarboxylase antizyme 3
chr1_+_34801704 0.71 ENSMUST00000047664.9
Rho guanine nucleotide exchange factor (GEF) 4
chr9_-_106656081 0.63 ENSMUST00000023959.7
glutamate receptor, metabotropic 2
chr11_-_70982987 0.62 ENSMUST00000078528.6
complement component 1, q subcomponent binding protein
chr13_-_36117269 0.62 ENSMUST00000053265.6
LYR motif containing 4
chr3_-_54735001 0.62 ENSMUST00000153224.1
exosome component 8
chr6_-_50261743 0.61 ENSMUST00000101405.3
ENSMUST00000165099.1
ENSMUST00000170142.1
deafness, autosomal dominant 5 (human)
chr2_-_62573905 0.56 ENSMUST00000102732.3
fibroblast activation protein
chr6_+_129397478 0.56 ENSMUST00000112081.2
ENSMUST00000112079.2
C-type lectin domain family 1, member b
chr5_-_138170992 0.54 ENSMUST00000139983.1
minichromosome maintenance deficient 7 (S. cerevisiae)
chr19_+_44989073 0.51 ENSMUST00000026225.8
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chr8_-_92356103 0.51 ENSMUST00000034183.3
RIKEN cDNA 4933436C20 gene
chr17_+_84511832 0.50 ENSMUST00000047206.5
pleckstrin homology domain containing, family H (with MyTH4 domain) member 2
chr16_-_4003750 0.48 ENSMUST00000171658.1
ENSMUST00000171762.1
SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae)
chr15_-_84105662 0.48 ENSMUST00000082365.5
sulfotransferase family 4A, member 1
chr11_+_83703991 0.47 ENSMUST00000092836.5
WAP four-disulfide core domain 17
chr18_-_42579652 0.47 ENSMUST00000054738.3
G protein-coupled receptor 151
chr10_+_76147451 0.42 ENSMUST00000020450.3
solute carrier family 5, member 4a
chr6_-_60829826 0.42 ENSMUST00000163779.1
synuclein, alpha
chr15_-_83367267 0.42 ENSMUST00000100370.1
ENSMUST00000178628.1
RIKEN cDNA 1700001L05 gene
chr9_+_59291565 0.41 ENSMUST00000026266.7
ADP-dependent glucokinase
chr11_+_24080664 0.39 ENSMUST00000118955.1
B cell CLL/lymphoma 11A (zinc finger protein)
chr7_+_13278778 0.39 ENSMUST00000098814.4
ENSMUST00000146998.1
ENSMUST00000185145.1
ligase I, DNA, ATP-dependent
chr14_-_54517353 0.36 ENSMUST00000023873.5
protein arginine N-methyltransferase 5
chr15_+_75616675 0.36 ENSMUST00000161785.1
ENSMUST00000054555.8
ENSMUST00000161752.1
zinc finger protein 41
chr7_-_126704816 0.34 ENSMUST00000032949.7
coronin, actin binding protein 1A
chr1_-_16104163 0.34 ENSMUST00000149566.1
ribosomal protein L7
chr10_-_25536114 0.32 ENSMUST00000179685.1
small leucine-rich protein 1
chr12_-_113260217 0.32 ENSMUST00000178282.1
immunoglobulin heavy constant alpha
chr1_+_62703667 0.32 ENSMUST00000114155.1
ENSMUST00000027112.6
ENSMUST00000063594.6
ENSMUST00000114157.2
neuropilin 2
chr4_-_117914968 0.32 ENSMUST00000036156.5
importin 13
chr9_+_31386187 0.31 ENSMUST00000086167.5
nuclear factor related to kappa B binding protein
chr5_-_39644597 0.30 ENSMUST00000152057.1
heparan sulfate (glucosamine) 3-O-sulfotransferase 1
chr2_+_30364227 0.29 ENSMUST00000077977.7
ENSMUST00000140075.2
family with sequence similarity 73, member B
chr7_+_19149722 0.29 ENSMUST00000049294.2
small nuclear ribonucleoprotein D2
chr11_+_120608469 0.28 ENSMUST00000106194.1
ENSMUST00000106195.2
neuropeptide B
chr4_-_117156144 0.28 ENSMUST00000102696.4
ribosomal protein S8
chr9_-_63602417 0.28 ENSMUST00000171243.1
ENSMUST00000163982.1
ENSMUST00000163624.1
IQ motif containing H
chr1_+_62703285 0.28 ENSMUST00000102822.2
ENSMUST00000075144.5
neuropilin 2
chr7_+_45785331 0.28 ENSMUST00000120005.1
ENSMUST00000123585.1
lemur tyrosine kinase 3
chr1_+_183388981 0.27 ENSMUST00000097043.5
TATA box binding protein (Tbp)-associated factor, RNA polymerase I, A
chr17_+_24728174 0.26 ENSMUST00000183214.1
ribosomal protein L3-like
chr10_+_80292453 0.26 ENSMUST00000068408.7
ENSMUST00000062674.6
ribosomal protein S15
chr4_-_132353605 0.24 ENSMUST00000155129.1
regulator of chromosome condensation 1
chr1_+_74153981 0.24 ENSMUST00000027372.7
ENSMUST00000106899.2
chemokine (C-X-C motif) receptor 2
chr16_-_96127604 0.23 ENSMUST00000133885.1
ENSMUST00000050884.7
high mobility group nucleosomal binding domain 1
chr9_+_110419750 0.23 ENSMUST00000035061.6
neutrophilic granule protein
chr16_+_8470763 0.21 ENSMUST00000046470.9
ENSMUST00000150790.1
ENSMUST00000142899.1
methyltransferase like 22
chr7_+_27607997 0.21 ENSMUST00000142365.1
thymoma viral proto-oncogene 2
chr7_-_18910377 0.21 ENSMUST00000139077.1
coiled-coil domain containing 61
chr11_+_88047302 0.21 ENSMUST00000139129.2
serine/arginine-rich splicing factor 1
chr7_-_4789541 0.21 ENSMUST00000168578.1
transmembrane protein 238
chr6_+_113378113 0.21 ENSMUST00000171058.1
ENSMUST00000156898.1
actin related protein 2/3 complex, subunit 4
chr5_-_36582381 0.21 ENSMUST00000141043.1
ENSMUST00000031094.8
TBC1 domain family, member 14
chr1_+_153652943 0.20 ENSMUST00000041776.5
regulator of G-protein signaling 8
chr7_+_126861947 0.20 ENSMUST00000037248.3
HIRA interacting protein 3
chrX_+_99821021 0.19 ENSMUST00000096363.2
transmembrane protein 28
chr7_-_126861648 0.19 ENSMUST00000129812.1
ENSMUST00000106342.1
INO80 complex subunit E
chr6_-_38124568 0.19 ENSMUST00000040259.4
ATPase, H+ transporting, lysosomal V0 subunit A4
chr3_+_138217814 0.19 ENSMUST00000090171.5
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr8_+_78213292 0.19 ENSMUST00000117845.1
ENSMUST00000126172.1
ENSMUST00000049395.8
tetratricopeptide repeat domain 29
chr1_-_179546261 0.19 ENSMUST00000027769.5
transcription factor B2, mitochondrial
chr15_+_34495302 0.19 ENSMUST00000052290.7
ENSMUST00000079028.5
processing of precursor 1, ribonuclease P/MRP family, (S. cerevisiae)
chr7_-_4604041 0.18 ENSMUST00000166650.1
protein tyrosine phosphatase, receptor type, H
chr2_-_84678828 0.18 ENSMUST00000111665.1
thioredoxin-related transmembrane protein 2
chr11_-_6267718 0.18 ENSMUST00000004507.4
ENSMUST00000151446.1
DEAD (Asp-Glu-Ala-Asp) box polypeptide 56
chr8_-_105701077 0.17 ENSMUST00000042608.6
adrenocortical dysplasia
chr5_-_149053038 0.16 ENSMUST00000085546.6
high mobility group box 1
chr11_-_70656467 0.15 ENSMUST00000131642.1
predicted gene 12319
chr15_+_83526854 0.15 ENSMUST00000016902.3
BCL2-interacting killer
chr7_+_35449035 0.15 ENSMUST00000118969.1
ENSMUST00000118383.1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 9
chr6_-_50261943 0.15 ENSMUST00000167893.1
deafness, autosomal dominant 5 (human)
chr11_-_45955465 0.15 ENSMUST00000011398.6
tRNA-histidine guanylyltransferase 1-like (S. cerevisiae)
chr1_-_152090308 0.15 ENSMUST00000044581.7
RIKEN cDNA 1700025G04 gene
chr18_+_9958147 0.14 ENSMUST00000025137.7
THO complex 1
chr8_-_68735058 0.14 ENSMUST00000136060.1
ENSMUST00000130214.1
ENSMUST00000078350.6
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr7_-_126861828 0.14 ENSMUST00000106343.1
INO80 complex subunit E
chr2_+_55411790 0.13 ENSMUST00000155997.1
ENSMUST00000128307.1
predicted gene 14033
chr17_+_27029259 0.13 ENSMUST00000053683.6
gametogenetin binding protein 1
chr7_-_120145286 0.13 ENSMUST00000033207.4
zona pellucida glycoprotein 2
chr5_-_120467296 0.12 ENSMUST00000132916.1
serine dehydratase-like
chr2_-_66440753 0.11 ENSMUST00000112371.2
ENSMUST00000138910.1
sodium channel, voltage-gated, type I, alpha
chr7_+_27607748 0.11 ENSMUST00000136962.1
thymoma viral proto-oncogene 2
chr2_+_3118335 0.11 ENSMUST00000115099.2
family with sequence similarity 171, member A1
chr10_+_61720592 0.11 ENSMUST00000080099.5
apoptosis-inducing factor, mitochondrion-associated 2
chr1_-_97661668 0.11 ENSMUST00000153115.1
ENSMUST00000142234.1
DNA segment, Chr 1, ERATO Doi 622, expressed
chr12_-_73286698 0.10 ENSMUST00000116420.2
TRM5 tRNA methyltransferase 5
chr11_+_120608492 0.09 ENSMUST00000061309.4
neuropeptide B
chr2_-_176149825 0.09 ENSMUST00000109049.3
ENSMUST00000179349.1
predicted gene 2004
chr6_-_101377342 0.09 ENSMUST00000151175.1
PDZ domain containing RING finger 3
chr19_-_6128208 0.09 ENSMUST00000025702.7
sorting nexin 15
chrX_-_74368547 0.09 ENSMUST00000155676.1
ubiquitin-like 4
chr16_-_36131156 0.09 ENSMUST00000161638.1
ENSMUST00000096090.2
cystatin A
chr19_-_44555398 0.08 ENSMUST00000167027.1
ENSMUST00000171415.1
ENSMUST00000026222.4
NADH dehydrogenase (ubiquinone) 1 beta subcomplex 8
chrX_-_95444789 0.08 ENSMUST00000084535.5
APC membrane recruitment 1
chr5_-_120777628 0.08 ENSMUST00000044833.8
2'-5' oligoadenylate synthetase 3
chr11_+_72435511 0.08 ENSMUST00000076443.3
gamma-glutamyltransferase 6
chr2_+_3118407 0.08 ENSMUST00000091505.4
family with sequence similarity 171, member A1
chr2_+_3118523 0.08 ENSMUST00000062934.6
family with sequence similarity 171, member A1
chr12_-_102439813 0.08 ENSMUST00000021607.8
legumain
chr5_-_39644634 0.08 ENSMUST00000053116.6
heparan sulfate (glucosamine) 3-O-sulfotransferase 1
chr5_-_149051300 0.08 ENSMUST00000110505.1
high mobility group box 1
chr11_-_74590065 0.07 ENSMUST00000145524.1
ENSMUST00000047488.7
RAP1 GTPase activating protein 2
chr2_+_101678403 0.07 ENSMUST00000004949.7
TNF receptor-associated factor 6
chr8_+_95633500 0.07 ENSMUST00000034094.9
GINS complex subunit 3 (Psf3 homolog)
chr7_+_35449154 0.07 ENSMUST00000032703.9
solute carrier family 7 (cationic amino acid transporter, y+ system), member 9
chr9_-_112185939 0.06 ENSMUST00000070218.5
cyclic AMP-regulated phosphoprotein, 21
chr6_+_36388055 0.06 ENSMUST00000172278.1
cholinergic receptor, muscarinic 2, cardiac
chr13_+_100669481 0.06 ENSMUST00000057325.7
ENSMUST00000170347.2
coiled-coil domain containing 125
chr11_-_78751656 0.05 ENSMUST00000059468.4
family with sequence similarity 58, member B
chr11_-_74590186 0.05 ENSMUST00000102521.1
RAP1 GTPase activating protein 2
chr19_+_12460749 0.05 ENSMUST00000081035.7
macrophage expressed gene 1
chr11_+_70451905 0.05 ENSMUST00000151013.1
ENSMUST00000019067.7
mediator of RNA polymerase II transcription, subunit 11 homolog (S. cerevisiae)
chr6_+_94500313 0.04 ENSMUST00000061118.8
solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 26
chr11_-_118248590 0.04 ENSMUST00000106305.2
cytohesin 1
chrX_-_160138375 0.04 ENSMUST00000033662.8
pyruvate dehydrogenase E1 alpha 1
chr2_+_136532266 0.03 ENSMUST00000121717.1
ankyrin repeat and EF-hand domain containing 1
chr14_-_100149764 0.03 ENSMUST00000097079.4
Kruppel-like factor 12
chr17_-_27029009 0.03 ENSMUST00000078691.5
BCL2-antagonist/killer 1
chr9_+_14860210 0.03 ENSMUST00000034408.5
ENSMUST00000115624.2
G protein-coupled receptor 83
chr10_-_39899238 0.03 ENSMUST00000178563.1
expressed sequence AA474331
chr12_+_86421782 0.03 ENSMUST00000021680.5
estrogen related receptor, beta
chr11_-_118415794 0.03 ENSMUST00000164927.1
calcium activated nucleotidase 1
chr17_-_56074932 0.03 ENSMUST00000019722.5
UBX domain protein 6
chr4_+_132638987 0.03 ENSMUST00000135299.1
ENSMUST00000081726.6
ENSMUST00000180250.1
ENSMUST00000020197.7
ENSMUST00000079157.4
eyes absent 3 homolog (Drosophila)
chr4_+_115563649 0.02 ENSMUST00000141033.1
ENSMUST00000030486.8
ENSMUST00000126645.1
ENSMUST00000030480.3
cytochrome P450, family 4, subfamily a, polypeptide 31
chr8_+_105701142 0.02 ENSMUST00000098444.2
par-6 (partitioning defective 6,) homolog alpha (C. elegans)
chrX_-_75380041 0.01 ENSMUST00000114085.2
coagulation factor VIII
chr5_+_98180866 0.01 ENSMUST00000112959.1
PR domain containing 8
chr19_+_34192229 0.01 ENSMUST00000054956.8
STAM binding protein like 1
chr18_+_20944607 0.01 ENSMUST00000050004.1
ring finger protein 125
chr9_-_112185726 0.00 ENSMUST00000160240.1
ENSMUST00000162065.1
cyclic AMP-regulated phosphoprotein, 21
chr10_-_13868779 0.00 ENSMUST00000105534.3
androgen-induced 1
chr19_-_5610038 0.00 ENSMUST00000113641.2
K(lysine) acetyltransferase 5
chr6_-_34955903 0.00 ENSMUST00000147169.1
RIKEN cDNA 2010107G12 gene
chr15_+_82298943 0.00 ENSMUST00000023089.3
WBP2 N-terminal like

Network of associatons between targets according to the STRING database.

First level regulatory network of Tbx21

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 4.0 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.4 3.8 GO:0033227 dsRNA transport(GO:0033227)
0.3 1.5 GO:1902961 positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) positive regulation of aspartic-type peptidase activity(GO:1905247)
0.2 0.6 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.2 0.6 GO:0034473 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.2 0.8 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.2 0.6 GO:0061552 vestibulocochlear nerve structural organization(GO:0021649) ganglion morphogenesis(GO:0061552) dorsal root ganglion morphogenesis(GO:1904835)
0.2 0.6 GO:0010710 regulation of collagen catabolic process(GO:0010710) negative regulation of extracellular matrix disassembly(GO:0010716)
0.2 0.5 GO:1904431 positive regulation of t-circle formation(GO:1904431)
0.1 0.4 GO:2000295 regulation of hydrogen peroxide catabolic process(GO:2000295)
0.1 0.2 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.1 0.4 GO:1904799 regulation of neuron remodeling(GO:1904799) negative regulation of neuron remodeling(GO:1904800)
0.1 0.2 GO:0002270 plasmacytoid dendritic cell activation(GO:0002270)
0.1 0.2 GO:0015811 L-cystine transport(GO:0015811)
0.1 0.4 GO:0060161 histone H4-R3 methylation(GO:0043985) positive regulation of dopamine receptor signaling pathway(GO:0060161)
0.1 0.2 GO:0016078 tRNA catabolic process(GO:0016078)
0.1 0.2 GO:0033030 negative regulation of neutrophil apoptotic process(GO:0033030)
0.1 0.2 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.1 0.3 GO:0032796 uropod organization(GO:0032796)
0.1 0.2 GO:1904742 regulation of telomeric DNA binding(GO:1904742)
0.1 0.4 GO:0033567 DNA replication, Okazaki fragment processing(GO:0033567)
0.1 0.3 GO:0097473 cellular response to light intensity(GO:0071484) cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.1 0.5 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 1.5 GO:0030220 platelet formation(GO:0030220)
0.0 0.2 GO:0006069 ethanol oxidation(GO:0006069)
0.0 0.2 GO:0071955 recycling endosome to Golgi transport(GO:0071955)
0.0 1.5 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.3 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.1 GO:0045829 negative regulation of isotype switching(GO:0045829)
0.0 0.1 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 1.1 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.0 0.3 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.2 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.1 GO:0006624 vacuolar protein processing(GO:0006624)
0.0 0.1 GO:0070900 mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.0 0.2 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.0 0.2 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.1 GO:0060468 prevention of polyspermy(GO:0060468)
0.0 0.3 GO:0042921 glucocorticoid receptor signaling pathway(GO:0042921)
0.0 0.2 GO:1990035 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.0 0.2 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.6 GO:0014047 glutamate secretion(GO:0014047)
0.0 0.1 GO:0007207 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.0 0.1 GO:2001012 mesenchymal cell differentiation involved in kidney development(GO:0072161) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.0 0.1 GO:0060700 regulation of ribonuclease activity(GO:0060700)
0.0 0.0 GO:0002352 B cell negative selection(GO:0002352)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 0.5 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.1 0.6 GO:0071438 invadopodium membrane(GO:0071438)
0.1 0.7 GO:0034709 methylosome(GO:0034709)
0.1 0.6 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.1 0.3 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.0 0.8 GO:0005652 nuclear lamina(GO:0005652)
0.0 0.6 GO:0031011 Ino80 complex(GO:0031011)
0.0 0.5 GO:0042555 MCM complex(GO:0042555)
0.0 0.3 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.2 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.2 GO:0042629 mast cell granule(GO:0042629)
0.0 0.2 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.2 GO:0070187 telosome(GO:0070187)
0.0 1.2 GO:0005871 kinesin complex(GO:0005871)
0.0 0.2 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.3 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.1 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.5 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 4.0 GO:0003875 ADP-ribosylarginine hydrolase activity(GO:0003875)
0.6 3.8 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.2 0.8 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.2 0.6 GO:0030984 kininogen binding(GO:0030984)
0.1 1.5 GO:0016151 nickel cation binding(GO:0016151)
0.1 0.5 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.1 0.4 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.1 0.6 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1 0.6 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640)
0.1 0.2 GO:0000402 open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402)
0.1 0.2 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.1 0.2 GO:0015275 stretch-activated, cation-selective, calcium channel activity(GO:0015275)
0.1 0.2 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.1 0.2 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.1 0.2 GO:0000171 ribonuclease MRP activity(GO:0000171)
0.1 0.4 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.1 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.0 0.2 GO:0019958 C-X-C chemokine binding(GO:0019958)
0.0 0.6 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.4 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 0.1 GO:0032190 acrosin binding(GO:0032190)
0.0 0.4 GO:1903136 cuprous ion binding(GO:1903136)
0.0 0.2 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.1 GO:0004794 L-threonine ammonia-lyase activity(GO:0004794)
0.0 0.1 GO:0047237 glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237) glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0 0.2 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.0 0.3 GO:1990446 U1 snRNP binding(GO:1990446)
0.0 0.3 GO:0008097 5S rRNA binding(GO:0008097)
0.0 1.5 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.2 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.1 GO:0016649 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.0 0.7 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.3 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.3 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.6 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.5 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.1 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.0 0.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 1.2 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 1.5 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 2.0 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.4 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.3 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.6 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 1.2 REACTOME KINESINS Genes involved in Kinesins
0.0 0.5 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.5 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.6 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.2 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.6 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.4 REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND Genes involved in Processive synthesis on the lagging strand
0.0 0.3 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.2 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.8 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.1 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.7 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 1.2 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.3 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination