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12D miR HR13_24

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Results for Rela_Rel_Nfkb1

Z-value: 2.14

Motif logo

Transcription factors associated with Rela_Rel_Nfkb1

Gene Symbol Gene ID Gene Info
ENSMUSG00000024927.7 v-rel reticuloendotheliosis viral oncogene homolog A (avian)
ENSMUSG00000020275.8 reticuloendotheliosis oncogene
ENSMUSG00000028163.11 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nfkb1mm10_v2_chr3_-_135691512_135691564-0.812.2e-03Click!
Relamm10_v2_chr19_+_5637475_5637486-0.701.6e-02Click!
Relmm10_v2_chr11_-_23770953_23771028-0.643.3e-02Click!

Activity profile of Rela_Rel_Nfkb1 motif

Sorted Z-values of Rela_Rel_Nfkb1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_165234689 4.64 ENSMUST00000065438.6
cadherin 22
chr5_+_90891234 3.80 ENSMUST00000031327.8
chemokine (C-X-C motif) ligand 1
chr5_-_92348871 3.44 ENSMUST00000038816.6
ENSMUST00000118006.1
chemokine (C-X-C motif) ligand 10
chr5_+_90759299 3.24 ENSMUST00000031318.4
chemokine (C-X-C motif) ligand 5
chr4_+_150927918 3.21 ENSMUST00000139826.1
ENSMUST00000116257.1
tumor necrosis factor receptor superfamily, member 9
chr15_-_31367527 3.20 ENSMUST00000076942.4
ENSMUST00000123325.1
ENSMUST00000110410.2
ankyrin repeat domain 33B
chr7_-_44815658 3.06 ENSMUST00000107893.1
activating transcription factor 5
chr9_-_7873157 2.85 ENSMUST00000159323.1
ENSMUST00000115673.2
baculoviral IAP repeat-containing 3
chr9_-_7873016 2.67 ENSMUST00000013949.8
baculoviral IAP repeat-containing 3
chr13_+_112464070 2.65 ENSMUST00000183663.1
ENSMUST00000184311.1
ENSMUST00000183886.1
interleukin 6 signal transducer
chr2_-_32387760 2.46 ENSMUST00000050785.8
lipocalin 2
chr1_+_150100093 2.44 ENSMUST00000035065.7
prostaglandin-endoperoxide synthase 2
chr19_+_6341121 2.38 ENSMUST00000025897.6
ENSMUST00000130382.1
mitogen-activated protein kinase kinase kinase kinase 2
chr1_-_135258449 2.27 ENSMUST00000003135.7
E74-like factor 3
chr9_-_7872983 2.23 ENSMUST00000115672.1
baculoviral IAP repeat-containing 3
chr18_-_4352944 2.22 ENSMUST00000025078.2
mitogen-activated protein kinase kinase kinase 8
chr14_-_30607808 2.17 ENSMUST00000112207.1
ENSMUST00000112206.1
ENSMUST00000112202.1
ENSMUST00000112203.1
protein kinase C, delta
chr19_+_46304709 2.10 ENSMUST00000073116.5
nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100
chr19_-_58454435 2.10 ENSMUST00000169850.1
glial cell line derived neurotrophic factor family receptor alpha 1
chr19_-_58454580 2.09 ENSMUST00000129100.1
ENSMUST00000123957.1
glial cell line derived neurotrophic factor family receptor alpha 1
chr4_+_115088708 2.09 ENSMUST00000171877.1
ENSMUST00000177647.1
ENSMUST00000106548.2
ENSMUST00000030488.2
PDZK1 interacting protein 1
chr17_-_34287770 1.99 ENSMUST00000174751.1
ENSMUST00000040655.6
histocompatibility 2, class II antigen A, alpha
chr2_-_103303179 1.99 ENSMUST00000090475.3
ets homologous factor
chr2_-_5063996 1.95 ENSMUST00000114996.1
optineurin
chr2_-_103303158 1.95 ENSMUST00000111176.2
ets homologous factor
chr11_+_100860447 1.93 ENSMUST00000107357.2
signal transducer and activator of transcription 5A
chr11_-_109298066 1.92 ENSMUST00000106706.1
regulator of G-protein signaling 9
chr13_+_18948344 1.90 ENSMUST00000003345.7
amphiphysin
chr7_+_28766747 1.89 ENSMUST00000170068.1
ENSMUST00000072965.4
sirtuin 2
chrX_+_164438039 1.88 ENSMUST00000033755.5
ankyrin repeat and SOCS box-containing 11
chr11_+_93098404 1.87 ENSMUST00000107859.1
ENSMUST00000042943.6
ENSMUST00000107861.1
ENSMUST00000107858.2
carbonic anhydrase 10
chr9_+_22188137 1.84 ENSMUST00000178901.1
zinc finger protein 872
chr17_+_35979851 1.82 ENSMUST00000087200.3
guanine nucleotide binding protein-like 1
chr2_+_144556229 1.80 ENSMUST00000143573.1
ENSMUST00000028916.8
ENSMUST00000155258.1
SEC23B (S. cerevisiae)
chr3_-_83841767 1.79 ENSMUST00000029623.9
toll-like receptor 2
chr2_+_144556306 1.76 ENSMUST00000155876.1
ENSMUST00000149697.1
SEC23B (S. cerevisiae)
chrX_+_164506320 1.76 ENSMUST00000033756.2
ankyrin repeat and SOCS box-containing 9
chr2_-_5063932 1.76 ENSMUST00000027986.4
optineurin
chr18_-_20059478 1.67 ENSMUST00000075214.2
ENSMUST00000039247.4
desmocollin 2
chr7_+_99535439 1.65 ENSMUST00000098266.2
ENSMUST00000179755.1
arrestin, beta 1
chr9_+_46998931 1.65 ENSMUST00000178065.1
predicted gene 4791
chr18_+_60803838 1.62 ENSMUST00000050487.8
ENSMUST00000097563.2
ENSMUST00000167610.1
CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)
chr17_+_33919332 1.61 ENSMUST00000025161.7
TAP binding protein
chr17_+_24878724 1.61 ENSMUST00000050714.6
insulin-like growth factor binding protein, acid labile subunit
chr2_-_152830615 1.58 ENSMUST00000146380.1
ENSMUST00000134902.1
ENSMUST00000134357.1
ENSMUST00000109820.3
BCL2-like 1
chrX_+_103321398 1.52 ENSMUST00000033689.2
caudal type homeobox 4
chr1_+_134193432 1.50 ENSMUST00000038445.6
myosin binding protein H
chr11_-_109298121 1.46 ENSMUST00000020920.3
regulator of G-protein signaling 9
chr9_-_14614949 1.46 ENSMUST00000013220.6
ENSMUST00000160770.1
angiomotin-like 1
chr11_-_106159902 1.43 ENSMUST00000064545.4
LIM domain containing 2
chr11_+_100860326 1.43 ENSMUST00000138083.1
signal transducer and activator of transcription 5A
chrX_+_7657260 1.41 ENSMUST00000033485.7
prickle homolog 3 (Drosophila)
chr8_-_25101985 1.39 ENSMUST00000128715.1
ENSMUST00000064883.6
pleckstrin homology domain-containing, family A (phosphoinositide binding specific) member 2
chr2_-_84743655 1.38 ENSMUST00000181711.1
predicted gene, 19426
chr6_-_5256226 1.38 ENSMUST00000125686.1
ENSMUST00000031773.2
paraoxonase 3
chr19_-_58455161 1.38 ENSMUST00000135730.1
ENSMUST00000152507.1
glial cell line derived neurotrophic factor family receptor alpha 1
chr10_-_19015347 1.36 ENSMUST00000019997.4
tumor necrosis factor, alpha-induced protein 3
chr7_-_99626936 1.36 ENSMUST00000178124.1
predicted gene 4980
chr4_+_100776664 1.35 ENSMUST00000030257.8
ENSMUST00000097955.2
cache domain containing 1
chr7_+_75455534 1.31 ENSMUST00000147005.1
ENSMUST00000166315.1
A kinase (PRKA) anchor protein 13
chr12_-_55492587 1.29 ENSMUST00000021413.7
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha
chr7_+_99535652 1.29 ENSMUST00000032995.8
ENSMUST00000162404.1
arrestin, beta 1
chr5_-_105293699 1.29 ENSMUST00000050011.8
guanylate binding protein 6
chr4_-_42168603 1.27 ENSMUST00000098121.3
predicted gene 13305
chr14_+_80000292 1.27 ENSMUST00000088735.3
olfactomedin 4
chr2_+_143546144 1.27 ENSMUST00000028905.9
proprotein convertase subtilisin/kexin type 2
chr8_+_84415348 1.19 ENSMUST00000121390.1
ENSMUST00000122053.1
calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
chr12_+_79029150 1.16 ENSMUST00000039928.5
pleckstrin homology domain containing, family H (with MyTH4 domain) member 1
chr18_+_37473538 1.15 ENSMUST00000050034.1
protocadherin beta 15
chr6_+_48841633 1.15 ENSMUST00000168406.1
transmembrane protein 176A
chr17_+_55952623 1.15 ENSMUST00000003274.6
Epstein-Barr virus induced gene 3
chr5_+_66968416 1.11 ENSMUST00000038188.7
LIM and calponin homology domains 1
chr10_-_127751707 1.11 ENSMUST00000079692.5
G protein-coupled receptor 182
chr11_+_100859492 1.09 ENSMUST00000107356.1
signal transducer and activator of transcription 5A
chr2_-_60881360 1.09 ENSMUST00000164147.1
ENSMUST00000112509.1
RNA binding motif, single stranded interacting protein 1
chr2_-_164443177 1.08 ENSMUST00000017153.3
syndecan 4
chr5_+_64970069 1.08 ENSMUST00000031080.8
family with sequence similarity 114, member A1
chr4_-_125127817 1.05 ENSMUST00000036188.7
zinc finger CCCH type containing 12A
chr2_+_120567687 1.02 ENSMUST00000028743.3
ENSMUST00000116437.1
ENSMUST00000153580.1
ENSMUST00000142278.1
synaptosomal-associated protein 23
chr11_-_47379405 1.01 ENSMUST00000077221.5
sarcoglycan, delta (dystrophin-associated glycoprotein)
chr6_+_48841476 1.01 ENSMUST00000101426.4
transmembrane protein 176A
chr18_+_84851338 1.01 ENSMUST00000160180.1
cytochrome b-5
chr11_-_54956047 1.01 ENSMUST00000155316.1
ENSMUST00000108889.3
ENSMUST00000126703.1
TNFAIP3 interacting protein 1
chr3_+_28263205 1.00 ENSMUST00000159236.2
TRAF2 and NCK interacting kinase
chr14_+_41131777 1.00 ENSMUST00000022314.3
ENSMUST00000170719.1
surfactant associated protein A1
chr3_-_102936093 1.00 ENSMUST00000029448.6
synaptonemal complex protein 1
chrX_-_162565514 1.00 ENSMUST00000154424.1
RALBP1 associated Eps domain containing protein 2
chr17_+_26933070 0.99 ENSMUST00000073724.5
PHD finger protein 1
chr2_-_157566319 0.99 ENSMUST00000109528.2
ENSMUST00000088494.2
bladder cancer associated protein homolog (human)
chr11_-_109298090 0.98 ENSMUST00000106704.2
regulator of G-protein signaling 9
chr2_+_120567652 0.96 ENSMUST00000110711.2
synaptosomal-associated protein 23
chr11_+_87664274 0.96 ENSMUST00000092800.5
ring finger protein 43
chr3_+_122729158 0.96 ENSMUST00000066728.5
phosphodiesterase 5A, cGMP-specific
chr1_-_136230289 0.96 ENSMUST00000150163.1
ENSMUST00000144464.1
RIKEN cDNA 5730559C18 gene
chr11_+_87664549 0.94 ENSMUST00000121782.2
ring finger protein 43
chr9_+_54698859 0.94 ENSMUST00000120452.1
DnaJ (Hsp40) homolog, subfamily A, member 4
chr1_+_135132693 0.93 ENSMUST00000049449.4
protein tyrosine phosphatase, non-receptor type 7
chr4_+_102589687 0.93 ENSMUST00000097949.4
ENSMUST00000106901.1
phosphodiesterase 4B, cAMP specific
chr11_+_53519725 0.92 ENSMUST00000108987.1
ENSMUST00000121334.1
ENSMUST00000117061.1
septin 8
chr8_-_25101734 0.92 ENSMUST00000098866.4
pleckstrin homology domain-containing, family A (phosphoinositide binding specific) member 2
chr10_-_95415484 0.92 ENSMUST00000172070.1
ENSMUST00000150432.1
suppressor of cytokine signaling 2
chr14_-_30626196 0.91 ENSMUST00000112210.3
ENSMUST00000112211.2
ENSMUST00000112208.1
protein kinase C, delta
chr13_+_33964659 0.90 ENSMUST00000021843.5
ENSMUST00000058978.7
NAD(P)H dehydrogenase, quinone 2
chr12_-_80132802 0.89 ENSMUST00000180643.1
RIKEN cDNA 2310015A10 gene
chr17_-_34862473 0.89 ENSMUST00000025229.4
ENSMUST00000176203.2
ENSMUST00000128767.1
complement factor B
chr2_-_151973387 0.89 ENSMUST00000109863.1
family with sequence similarity 110, member A
chr12_+_52699297 0.88 ENSMUST00000095737.3
A kinase (PRKA) anchor protein 6
chr2_-_151973840 0.88 ENSMUST00000109865.1
ENSMUST00000109864.1
family with sequence similarity 110, member A
chr6_-_131313827 0.88 ENSMUST00000049150.1
serine/threonine/tyrosine kinase 1
chr10_-_7780866 0.87 ENSMUST00000124838.1
ENSMUST00000039763.7
glycoprotein integral membrane 1
chr7_-_127014585 0.86 ENSMUST00000165096.2
major vault protein
chr11_+_53519920 0.86 ENSMUST00000147912.1
septin 8
chrX_+_139684980 0.84 ENSMUST00000096313.3
TBC1 domain family, member 8B
chr19_+_46305682 0.83 ENSMUST00000111881.2
nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100
chr16_-_11176056 0.82 ENSMUST00000142389.1
ENSMUST00000138185.1
zinc finger CCCH type containing 7 A
chr16_-_55838827 0.82 ENSMUST00000096026.2
ENSMUST00000036273.6
ENSMUST00000114457.1
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, zeta
chr8_-_71676674 0.82 ENSMUST00000066837.4
predicted gene 9933
chr7_-_127930066 0.82 ENSMUST00000032988.8
protease, serine, 8 (prostasin)
chr11_+_114727384 0.81 ENSMUST00000069325.7
dynein, axonemal, intermediate chain 2
chr8_-_99416397 0.81 ENSMUST00000155527.1
ENSMUST00000142129.1
ENSMUST00000093249.4
ENSMUST00000142475.2
ENSMUST00000128860.1
cadherin 8
chr4_-_40239779 0.81 ENSMUST00000037907.6
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr1_+_109983006 0.81 ENSMUST00000145188.1
cadherin 7, type 2
chr1_-_182282218 0.80 ENSMUST00000133052.1
degenerative spermatocyte homolog 1 (Drosophila)
chr16_+_93683184 0.80 ENSMUST00000039620.6
carbonyl reductase 3
chr11_-_83578496 0.80 ENSMUST00000019266.5
chemokine (C-C motif) ligand 9
chr6_-_48841098 0.80 ENSMUST00000101429.4
transmembrane protein 176B
chr11_+_53519871 0.79 ENSMUST00000120878.2
septin 8
chr7_-_19629355 0.78 ENSMUST00000049912.8
ENSMUST00000094762.3
ENSMUST00000098754.4
avian reticuloendotheliosis viral (v-rel) oncogene related B
chr1_-_5019342 0.78 ENSMUST00000002533.8
regulator of G-protein signaling 20
chr17_+_35821675 0.78 ENSMUST00000003635.6
immediate early response 3
chr15_-_75747922 0.77 ENSMUST00000062002.4
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein A (avian)
chr5_+_24413406 0.77 ENSMUST00000049346.5
acid-sensing (proton-gated) ion channel 3
chr12_+_111442453 0.76 ENSMUST00000102745.3
tumor necrosis factor, alpha-induced protein 2
chr5_+_66968559 0.76 ENSMUST00000127184.1
LIM and calponin homology domains 1
chr8_+_36457548 0.75 ENSMUST00000135373.1
ENSMUST00000147525.1
RIKEN cDNA 6430573F11 gene
chr1_+_109982710 0.75 ENSMUST00000112701.1
cadherin 7, type 2
chrX_-_102908672 0.75 ENSMUST00000119624.1
ENSMUST00000033686.1
DMRT-like family C1a
chr6_-_48840988 0.75 ENSMUST00000164733.1
transmembrane protein 176B
chr8_+_71676233 0.74 ENSMUST00000110013.3
ENSMUST00000051995.7
Janus kinase 3
chr11_-_69880971 0.74 ENSMUST00000050555.3
potassium channel tetramerisation domain containing 11
chr16_+_23290464 0.74 ENSMUST00000115335.1
beta galactoside alpha 2,6 sialyltransferase 1
chr10_-_75797528 0.73 ENSMUST00000120177.1
glutathione S-transferase, theta 1
chr4_+_43059028 0.73 ENSMUST00000163653.1
ENSMUST00000107952.2
ENSMUST00000107953.2
unc-13 homolog B (C. elegans)
chr17_+_47436731 0.73 ENSMUST00000150819.2
expressed sequence AI661453
chr1_+_40266578 0.72 ENSMUST00000114795.1
interleukin 1 receptor, type I
chr7_-_109616548 0.72 ENSMUST00000077909.1
ENSMUST00000084738.3
suppression of tumorigenicity 5
chr14_-_70429072 0.71 ENSMUST00000048129.4
piwi-like RNA-mediated gene silencing 2
chr19_+_53529100 0.71 ENSMUST00000038287.6
dual specificity phosphatase 5
chr2_-_66634952 0.71 ENSMUST00000100064.2
ENSMUST00000100063.2
sodium channel, voltage-gated, type IX, alpha
chr3_+_89421619 0.70 ENSMUST00000094378.3
ENSMUST00000137793.1
src homology 2 domain-containing transforming protein C1
chr11_-_58502554 0.69 ENSMUST00000170501.2
ENSMUST00000081743.2
olfactory receptor 331
chr3_-_116423930 0.68 ENSMUST00000106491.2
CDC14 cell division cycle 14A
chr4_-_40239700 0.68 ENSMUST00000142055.1
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr18_+_51117754 0.67 ENSMUST00000116639.2
proline rich 16
chr4_-_101265236 0.67 ENSMUST00000149297.1
ENSMUST00000102781.3
Janus kinase 1
chr3_-_116424007 0.66 ENSMUST00000090464.4
CDC14 cell division cycle 14A
chr2_-_152831112 0.65 ENSMUST00000128172.1
BCL2-like 1
chr4_-_135272798 0.64 ENSMUST00000037099.8
chloride intracellular channel 4 (mitochondrial)
chr10_-_12964252 0.64 ENSMUST00000163425.1
ENSMUST00000042861.5
syntaxin 11
chr18_+_37484955 0.64 ENSMUST00000053856.4
protocadherin beta 17
chr13_+_25056206 0.64 ENSMUST00000069614.6
doublecortin domain containing 2a
chr14_+_55591708 0.64 ENSMUST00000019443.8
ring finger protein 31
chr19_+_55741810 0.63 ENSMUST00000111657.3
ENSMUST00000061496.9
ENSMUST00000041717.7
ENSMUST00000111662.4
transcription factor 7 like 2, T cell specific, HMG box
chr17_+_45555693 0.63 ENSMUST00000024742.7
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, epsilon
chr8_+_114133557 0.63 ENSMUST00000073521.5
ENSMUST00000066514.6
nudix (nucleoside diphosphate linked moiety X)-type motif 7
chr3_-_121263314 0.63 ENSMUST00000029777.7
transmembrane protein 56
chr15_-_79834323 0.63 ENSMUST00000177316.2
ENSMUST00000175858.2
neuronal pentraxin receptor
chr5_-_137116177 0.63 ENSMUST00000054384.5
ENSMUST00000152207.1
tripartite motif-containing 56
chr9_-_44526397 0.62 ENSMUST00000062215.7
chemokine (C-X-C motif) receptor 5
chr9_-_31131817 0.62 ENSMUST00000034478.2
suppression of tumorigenicity 14 (colon carcinoma)
chr5_+_30013141 0.62 ENSMUST00000026845.7
interleukin 6
chr2_-_6213033 0.61 ENSMUST00000042658.2
enoyl Coenzyme A hydratase domain containing 3
chr8_+_114133635 0.61 ENSMUST00000147605.1
ENSMUST00000134593.1
nudix (nucleoside diphosphate linked moiety X)-type motif 7
chr7_+_75848338 0.61 ENSMUST00000092073.5
ENSMUST00000171155.2
kelch-like 25
chr2_+_62664279 0.61 ENSMUST00000028257.2
grancalcin
chr8_-_25201349 0.61 ENSMUST00000084512.4
ENSMUST00000084030.4
transforming, acidic coiled-coil containing protein 1
chr8_+_54954728 0.60 ENSMUST00000033915.7
glycoprotein m6a
chr6_-_48841373 0.60 ENSMUST00000166247.1
transmembrane protein 176B
chr7_-_29281977 0.60 ENSMUST00000098604.4
ENSMUST00000108236.3
serine protease inhibitor, Kunitz type 2
chr2_-_152830266 0.60 ENSMUST00000140436.1
BCL2-like 1
chr14_+_65970610 0.60 ENSMUST00000127387.1
clusterin
chr3_-_121263159 0.59 ENSMUST00000128909.1
transmembrane protein 56
chr6_-_129275360 0.59 ENSMUST00000032259.3
CD69 antigen
chr10_+_75935573 0.59 ENSMUST00000058906.6
coiled-coil-helix-coiled-coil-helix domain containing 10
chr7_-_57387172 0.58 ENSMUST00000068911.6
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 3
chr1_-_172590463 0.58 ENSMUST00000065679.6
SLAM family member 8
chr5_+_43818893 0.58 ENSMUST00000101237.4
bone marrow stromal cell antigen 1
chr10_+_69219357 0.58 ENSMUST00000172261.1
Rho-related BTB domain containing 1
chr5_+_114568016 0.58 ENSMUST00000043650.7
family with sequence similarity 222, member A
chr3_-_113258837 0.58 ENSMUST00000098673.3
amylase 2a5
chr18_+_36560581 0.57 ENSMUST00000155329.2
ankyrin repeat and KH domain containing 1
chr2_-_156839790 0.57 ENSMUST00000134838.1
ENSMUST00000137463.1
ENSMUST00000149275.2
predicted gene 14230
chr11_-_23770953 0.56 ENSMUST00000102864.3
reticuloendotheliosis oncogene
chr7_-_30861470 0.56 ENSMUST00000052700.3
free fatty acid receptor 1
chr13_+_51846673 0.56 ENSMUST00000021903.2
growth arrest and DNA-damage-inducible 45 gamma
chr5_-_30960236 0.55 ENSMUST00000088063.2
prolactin regulatory element binding
chr5_-_17835857 0.55 ENSMUST00000082367.6
CD36 antigen
chr12_+_111442653 0.55 ENSMUST00000109792.1
tumor necrosis factor, alpha-induced protein 2
chr1_+_58795371 0.55 ENSMUST00000027189.8
caspase 8
chr8_-_45410539 0.54 ENSMUST00000034056.4
ENSMUST00000167106.1
toll-like receptor 3

Network of associatons between targets according to the STRING database.

First level regulatory network of Rela_Rel_Nfkb1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 7.0 GO:0070948 regulation of neutrophil mediated cytotoxicity(GO:0070948) regulation of neutrophil mediated killing of symbiont cell(GO:0070949)
1.1 4.5 GO:0060376 positive regulation of mast cell differentiation(GO:0060376)
1.0 2.9 GO:0002266 follicular dendritic cell activation(GO:0002266) follicular dendritic cell differentiation(GO:0002268)
0.9 2.7 GO:0070104 negative regulation of interleukin-6-mediated signaling pathway(GO:0070104)
0.9 3.4 GO:1901740 negative regulation of myoblast fusion(GO:1901740)
0.8 2.4 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.8 3.2 GO:2001183 negative regulation of interleukin-12 secretion(GO:2001183)
0.7 3.7 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.7 2.8 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.7 2.8 GO:0046898 response to cycloheximide(GO:0046898)
0.6 4.3 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
0.6 3.1 GO:0060697 glucosylceramide catabolic process(GO:0006680) positive regulation of phospholipid catabolic process(GO:0060697)
0.6 1.8 GO:0070340 cell surface pattern recognition receptor signaling pathway(GO:0002752) positive regulation of interleukin-18 production(GO:0032741) response to immune response of other organism involved in symbiotic interaction(GO:0052564) response to host immune response(GO:0052572) detection of bacterial lipopeptide(GO:0070340) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.6 2.9 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.5 1.6 GO:0002631 regulation of granuloma formation(GO:0002631) negative regulation of granuloma formation(GO:0002632) regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) tolerance induction to lipopolysaccharide(GO:0072573)
0.5 7.8 GO:1902916 positive regulation of protein polyubiquitination(GO:1902916)
0.5 1.4 GO:0009804 coumarin metabolic process(GO:0009804) phenylpropanoid catabolic process(GO:0046271)
0.4 1.8 GO:0033869 coenzyme A catabolic process(GO:0015938) nucleoside bisphosphate catabolic process(GO:0033869) ribonucleoside bisphosphate catabolic process(GO:0034031) purine nucleoside bisphosphate catabolic process(GO:0034034) acetyl-CoA catabolic process(GO:0046356)
0.4 1.3 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.4 1.3 GO:0002730 regulation of dendritic cell cytokine production(GO:0002730)
0.4 2.5 GO:1901678 iron coordination entity transport(GO:1901678)
0.4 1.2 GO:0060671 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.4 1.2 GO:0031335 regulation of sulfur amino acid metabolic process(GO:0031335)
0.4 1.6 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.4 1.1 GO:0048209 regulation of vesicle targeting, to, from or within Golgi(GO:0048209)
0.3 1.0 GO:1990868 response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869)
0.3 1.6 GO:0002905 mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
0.3 1.0 GO:0006657 CDP-choline pathway(GO:0006657)
0.3 1.3 GO:0030070 insulin processing(GO:0030070)
0.3 1.9 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.3 1.3 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
0.3 1.5 GO:0035546 detection of virus(GO:0009597) interferon-beta secretion(GO:0035546) regulation of interferon-beta secretion(GO:0035547) positive regulation of interferon-beta secretion(GO:0035549)
0.3 0.6 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.3 0.5 GO:1902226 regulation of macrophage colony-stimulating factor signaling pathway(GO:1902226) regulation of response to macrophage colony-stimulating factor(GO:1903969) regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903972)
0.3 0.8 GO:0042374 phylloquinone metabolic process(GO:0042374) phylloquinone catabolic process(GO:0042376) quinone catabolic process(GO:1901662)
0.3 0.8 GO:0098501 polynucleotide dephosphorylation(GO:0098501)
0.2 1.7 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
0.2 2.0 GO:0098881 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.2 0.7 GO:0003245 cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.2 0.7 GO:0042196 dichloromethane metabolic process(GO:0018900) chlorinated hydrocarbon metabolic process(GO:0042196) halogenated hydrocarbon metabolic process(GO:0042197)
0.2 1.6 GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.2 1.1 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
0.2 5.4 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.2 0.6 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.2 1.0 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.2 1.0 GO:0050915 sensory perception of sour taste(GO:0050915)
0.2 3.1 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.2 1.0 GO:0070423 nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423) nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070431)
0.2 0.7 GO:1990743 protein sialylation(GO:1990743)
0.2 0.5 GO:0071726 response to linoleic acid(GO:0070543) response to diacyl bacterial lipopeptide(GO:0071724) cellular response to diacyl bacterial lipopeptide(GO:0071726) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.2 1.5 GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.2 0.7 GO:0010286 heat acclimation(GO:0010286)
0.2 0.7 GO:0000966 RNA 5'-end processing(GO:0000966)
0.2 0.9 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.2 1.7 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.2 0.5 GO:0015881 creatine transport(GO:0015881)
0.2 0.7 GO:0036015 response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016)
0.2 1.0 GO:0007256 activation of JNKK activity(GO:0007256)
0.2 1.7 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.2 1.0 GO:0006116 NADH oxidation(GO:0006116)
0.2 0.6 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.2 0.5 GO:0034769 basement membrane disassembly(GO:0034769)
0.2 0.5 GO:0002023 reduction of food intake in response to dietary excess(GO:0002023)
0.2 2.0 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.1 0.4 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.1 0.7 GO:1990839 response to endothelin(GO:1990839)
0.1 2.1 GO:0060056 mammary gland involution(GO:0060056)
0.1 0.5 GO:1901421 regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980) positive regulation of response to alcohol(GO:1901421)
0.1 0.3 GO:0097343 ripoptosome assembly(GO:0097343) ripoptosome assembly involved in necroptotic process(GO:1901026)
0.1 0.6 GO:0032329 serine transport(GO:0032329)
0.1 1.1 GO:0008228 opsonization(GO:0008228)
0.1 0.4 GO:0015746 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.1 0.4 GO:0035964 COPI-coated vesicle budding(GO:0035964)
0.1 0.7 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.1 1.1 GO:0035092 sperm chromatin condensation(GO:0035092)
0.1 0.3 GO:1900060 negative regulation of ceramide biosynthetic process(GO:1900060)
0.1 0.8 GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.1 2.3 GO:0006903 vesicle targeting(GO:0006903)
0.1 0.2 GO:0060424 foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492)
0.1 0.2 GO:0097527 necroptotic signaling pathway(GO:0097527)
0.1 0.3 GO:0048295 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397) positive regulation of isotype switching to IgE isotypes(GO:0048295) positive regulation of corticotropin-releasing hormone secretion(GO:0051466)
0.1 0.4 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.1 1.5 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.1 0.5 GO:0046882 negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.1 0.3 GO:0009182 purine deoxyribonucleotide biosynthetic process(GO:0009153) purine deoxyribonucleoside diphosphate metabolic process(GO:0009182) dGDP metabolic process(GO:0046066) GDP metabolic process(GO:0046710)
0.1 0.3 GO:0097051 establishment of protein localization to endoplasmic reticulum membrane(GO:0097051)
0.1 0.6 GO:1902847 regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.1 0.3 GO:0021577 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)
0.1 1.6 GO:0051601 exocyst localization(GO:0051601)
0.1 0.1 GO:1903660 regulation of complement-dependent cytotoxicity(GO:1903659) negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.1 0.4 GO:0032379 positive regulation of intracellular lipid transport(GO:0032379) positive regulation of intracellular sterol transport(GO:0032382) positive regulation of intracellular cholesterol transport(GO:0032385) lipid hydroperoxide transport(GO:1901373)
0.1 1.6 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.1 0.5 GO:0060546 negative regulation of necroptotic process(GO:0060546)
0.1 0.4 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.1 0.5 GO:1902414 protein localization to cell junction(GO:1902414)
0.1 0.3 GO:0006481 C-terminal protein methylation(GO:0006481)
0.1 0.4 GO:0046967 cytosol to ER transport(GO:0046967)
0.1 0.3 GO:2000110 negative regulation of macrophage apoptotic process(GO:2000110)
0.1 0.5 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.1 0.4 GO:0001661 conditioned taste aversion(GO:0001661)
0.1 0.8 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)
0.1 0.4 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.1 0.2 GO:1903279 regulation of calcium:sodium antiporter activity(GO:1903279)
0.1 0.2 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.1 0.9 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.1 0.5 GO:0002756 MyD88-independent toll-like receptor signaling pathway(GO:0002756)
0.1 0.2 GO:0090481 pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.1 1.6 GO:0044406 adhesion of symbiont to host(GO:0044406)
0.1 0.2 GO:1900477 negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter(GO:1900477)
0.1 0.2 GO:0002019 regulation of renal output by angiotensin(GO:0002019)
0.1 1.3 GO:0071378 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.1 0.6 GO:0010909 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) embryonic hindgut morphogenesis(GO:0048619)
0.1 0.3 GO:1904566 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.1 0.5 GO:1904628 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.1 0.8 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.1 0.1 GO:0035990 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.1 0.4 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.1 0.3 GO:0070295 renal water absorption(GO:0070295)
0.1 1.0 GO:0031953 negative regulation of protein autophosphorylation(GO:0031953)
0.1 0.2 GO:1900227 positive regulation of NLRP3 inflammasome complex assembly(GO:1900227)
0.1 0.7 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.1 0.8 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 0.7 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 0.9 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 0.4 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.1 0.2 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.1 0.2 GO:2000556 regulation of T-helper 1 cell cytokine production(GO:2000554) positive regulation of T-helper 1 cell cytokine production(GO:2000556)
0.1 0.5 GO:0070862 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.1 0.8 GO:0036158 outer dynein arm assembly(GO:0036158)
0.1 0.5 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.0 0.6 GO:0099500 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.0 0.6 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.1 GO:0002220 innate immune response activating cell surface receptor signaling pathway(GO:0002220)
0.0 0.1 GO:0002925 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874) positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.0 1.0 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.1 GO:0039526 suppression by virus of host apoptotic process(GO:0019050) modulation by virus of host apoptotic process(GO:0039526)
0.0 0.9 GO:1904707 positive regulation of vascular smooth muscle cell proliferation(GO:1904707)
0.0 0.2 GO:0021564 vagus nerve development(GO:0021564)
0.0 0.1 GO:0071314 cellular response to cocaine(GO:0071314)
0.0 0.5 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.3 GO:0009137 purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
0.0 0.2 GO:0090273 regulation of somatostatin secretion(GO:0090273)
0.0 0.2 GO:0072362 regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072362)
0.0 0.7 GO:0007263 nitric oxide mediated signal transduction(GO:0007263)
0.0 0.1 GO:0035585 calcium-mediated signaling using extracellular calcium source(GO:0035585)
0.0 0.4 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.4 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.2 GO:0035553 oxidative single-stranded RNA demethylation(GO:0035553)
0.0 0.1 GO:0019747 regulation of isoprenoid metabolic process(GO:0019747) regulation of vitamin A metabolic process(GO:1901738)
0.0 0.3 GO:1903912 negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:1903912)
0.0 0.2 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0 0.3 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.3 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 0.1 GO:0000066 mitochondrial ornithine transport(GO:0000066)
0.0 0.5 GO:0002829 negative regulation of type 2 immune response(GO:0002829)
0.0 0.4 GO:0046541 saliva secretion(GO:0046541)
0.0 3.7 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 0.4 GO:2000254 regulation of male germ cell proliferation(GO:2000254)
0.0 0.6 GO:0032506 cytokinetic process(GO:0032506)
0.0 0.0 GO:0060664 epithelial cell proliferation involved in salivary gland morphogenesis(GO:0060664)
0.0 0.3 GO:1902031 malate metabolic process(GO:0006108) regulation of NADP metabolic process(GO:1902031)
0.0 0.1 GO:0090427 activation of meiosis(GO:0090427)
0.0 0.5 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.3 GO:0014827 intestine smooth muscle contraction(GO:0014827)
0.0 1.0 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0 0.1 GO:1900535 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) fatty-acyl-CoA catabolic process(GO:0036115) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.0 0.1 GO:0032962 positive regulation of inositol trisphosphate biosynthetic process(GO:0032962)
0.0 0.5 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.0 0.3 GO:0040031 snRNA modification(GO:0040031)
0.0 0.8 GO:0030262 cellular component disassembly involved in execution phase of apoptosis(GO:0006921) apoptotic nuclear changes(GO:0030262)
0.0 0.3 GO:0033216 ferric iron import(GO:0033216) ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.0 0.3 GO:0032274 gonadotropin secretion(GO:0032274)
0.0 0.6 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.7 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.8 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.3 GO:0036309 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.0 0.3 GO:0043416 regulation of skeletal muscle tissue regeneration(GO:0043416)
0.0 0.8 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.2 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0 1.5 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
0.0 0.1 GO:0055099 response to high density lipoprotein particle(GO:0055099)
0.0 0.7 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.1 GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
0.0 0.2 GO:0015961 diadenosine polyphosphate catabolic process(GO:0015961)
0.0 4.6 GO:0007601 visual perception(GO:0007601)
0.0 0.3 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.3 GO:0042048 olfactory behavior(GO:0042048)
0.0 0.3 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.0 0.1 GO:0032055 negative regulation of translation in response to stress(GO:0032055)
0.0 0.3 GO:0002072 optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.0 0.6 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.4 GO:0046498 S-adenosylhomocysteine metabolic process(GO:0046498)
0.0 0.1 GO:2000630 positive regulation of miRNA metabolic process(GO:2000630)
0.0 0.2 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.0 1.5 GO:0035690 cellular response to drug(GO:0035690)
0.0 0.1 GO:0021830 substrate-independent telencephalic tangential migration(GO:0021826) interneuron migration from the subpallium to the cortex(GO:0021830) substrate-independent telencephalic tangential interneuron migration(GO:0021843)
0.0 0.2 GO:0036159 inner dynein arm assembly(GO:0036159)
0.0 0.1 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 0.9 GO:0033006 regulation of mast cell activation involved in immune response(GO:0033006) regulation of mast cell degranulation(GO:0043304)
0.0 0.7 GO:0048266 behavioral response to pain(GO:0048266)
0.0 0.2 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 3.7 GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation(GO:0050731)
0.0 0.1 GO:0034393 positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.0 0.5 GO:0050961 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0 0.3 GO:2000251 regulation of establishment of cell polarity(GO:2000114) positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.6 GO:0030890 positive regulation of B cell proliferation(GO:0030890)
0.0 0.2 GO:0032495 response to muramyl dipeptide(GO:0032495)
0.0 0.1 GO:2001184 positive regulation of interleukin-12 secretion(GO:2001184)
0.0 0.1 GO:0051013 microtubule severing(GO:0051013)
0.0 0.1 GO:0021993 initiation of neural tube closure(GO:0021993)
0.0 0.1 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.0 0.3 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.5 GO:0042501 serine phosphorylation of STAT protein(GO:0042501)
0.0 0.1 GO:0016095 polyprenol catabolic process(GO:0016095)
0.0 0.5 GO:0034063 stress granule assembly(GO:0034063)
0.0 1.7 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.8 GO:0009409 response to cold(GO:0009409)
0.0 2.7 GO:0007416 synapse assembly(GO:0007416)
0.0 0.1 GO:0046874 quinolinate metabolic process(GO:0046874)
0.0 0.9 GO:0009948 anterior/posterior axis specification(GO:0009948)
0.0 0.5 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.1 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.0 0.4 GO:0007530 sex determination(GO:0007530)
0.0 0.4 GO:0039694 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.0 0.4 GO:0030575 nuclear body organization(GO:0030575)
0.0 0.1 GO:0006983 ER overload response(GO:0006983)
0.0 0.3 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.0 0.6 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.0 0.2 GO:0019372 lipoxygenase pathway(GO:0019372)
0.0 0.1 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 0.3 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.0 0.1 GO:0031642 negative regulation of myelination(GO:0031642)
0.0 0.8 GO:0010765 positive regulation of sodium ion transport(GO:0010765)
0.0 0.0 GO:0019448 cysteine catabolic process(GO:0009093) L-cysteine catabolic process(GO:0019448) L-cysteine metabolic process(GO:0046439)
0.0 0.0 GO:0042723 thiamine metabolic process(GO:0006772) thiamine-containing compound metabolic process(GO:0042723)
0.0 0.6 GO:0010524 positive regulation of calcium ion transport into cytosol(GO:0010524)
0.0 0.1 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.0 0.2 GO:0097062 dendritic spine maintenance(GO:0097062)
0.0 0.2 GO:0001865 NK T cell differentiation(GO:0001865)
0.0 0.8 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 0.4 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.2 GO:0090026 positive regulation of monocyte chemotaxis(GO:0090026)
0.0 0.2 GO:0048490 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.3 GO:2000479 regulation of cAMP-dependent protein kinase activity(GO:2000479)
0.0 0.3 GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.0 0.2 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.0 0.0 GO:0007494 midgut development(GO:0007494)
0.0 0.1 GO:0090161 Golgi ribbon formation(GO:0090161)
0.0 0.4 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.0 0.1 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407) positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.0 GO:0060853 negative regulation of smooth muscle cell apoptotic process(GO:0034392) arterial endothelial cell fate commitment(GO:0060844) blood vessel endothelial cell fate commitment(GO:0060846) endothelial cell fate specification(GO:0060847) Notch signaling pathway involved in arterial endothelial cell fate commitment(GO:0060853) regulation of cell adhesion involved in heart morphogenesis(GO:0061344) blood vessel lumenization(GO:0072554) blood vessel endothelial cell fate specification(GO:0097101) positive regulation of ephrin receptor signaling pathway(GO:1901189)
0.0 0.2 GO:0032757 positive regulation of interleukin-8 production(GO:0032757)
0.0 0.4 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.0 0.0 GO:0006542 glutamine biosynthetic process(GO:0006542)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 2.9 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.9 2.7 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.3 1.9 GO:0033010 paranodal junction(GO:0033010)
0.3 0.6 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.3 3.6 GO:0042613 MHC class II protein complex(GO:0042613)
0.3 3.9 GO:0042581 specific granule(GO:0042581)
0.3 2.8 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.3 2.0 GO:0042825 TAP complex(GO:0042825)
0.3 1.3 GO:0044305 calyx of Held(GO:0044305)
0.3 3.8 GO:0030127 COPII vesicle coat(GO:0030127)
0.2 1.0 GO:0000802 transverse filament(GO:0000802)
0.2 1.4 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.2 0.4 GO:0070820 tertiary granule(GO:0070820)
0.2 0.5 GO:0030690 Noc1p-Noc2p complex(GO:0030690)
0.2 0.5 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.2 0.5 GO:0043512 inhibin-betaglycan-ActRII complex(GO:0034673) inhibin A complex(GO:0043512)
0.2 0.6 GO:0071797 LUBAC complex(GO:0071797)
0.2 1.4 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.2 2.7 GO:0031143 pseudopodium(GO:0031143)
0.1 1.0 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.1 1.0 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 0.7 GO:1990923 PET complex(GO:1990923)
0.1 0.4 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.1 0.2 GO:0032127 dense core granule membrane(GO:0032127)
0.1 0.7 GO:0031933 telomeric heterochromatin(GO:0031933)
0.1 1.2 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 1.2 GO:0020005 symbiont-containing vacuole membrane(GO:0020005)
0.1 1.0 GO:0042587 glycogen granule(GO:0042587)
0.1 0.5 GO:0042382 paraspeckles(GO:0042382)
0.1 0.5 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1 0.3 GO:0035339 SPOTS complex(GO:0035339)
0.1 0.3 GO:0097058 CRLF-CLCF1 complex(GO:0097058) CNTFR-CLCF1 complex(GO:0097059)
0.1 0.2 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.1 0.2 GO:0005899 insulin receptor complex(GO:0005899)
0.1 4.3 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 0.2 GO:0034657 GID complex(GO:0034657)
0.1 0.7 GO:0000138 Golgi trans cisterna(GO:0000138)
0.1 1.5 GO:0005859 muscle myosin complex(GO:0005859)
0.1 0.6 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.1 0.4 GO:0030870 Mre11 complex(GO:0030870)
0.1 0.5 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.1 1.1 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.1 1.6 GO:0030057 desmosome(GO:0030057)
0.1 0.2 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.1 0.4 GO:0008091 spectrin(GO:0008091)
0.1 1.3 GO:0000145 exocyst(GO:0000145)
0.1 0.5 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.1 0.2 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.1 0.7 GO:0036157 outer dynein arm(GO:0036157)
0.1 0.8 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.6 GO:0060091 kinocilium(GO:0060091)
0.0 0.6 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.6 GO:0097418 neurofibrillary tangle(GO:0097418)
0.0 15.6 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.4 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.9 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.2 GO:0031501 mannosyltransferase complex(GO:0031501)
0.0 0.5 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.0 0.7 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 1.5 GO:0008180 COP9 signalosome(GO:0008180)
0.0 1.1 GO:0005771 multivesicular body(GO:0005771)
0.0 0.9 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 12.3 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 0.1 GO:0031094 platelet dense tubular network(GO:0031094) platelet dense tubular network membrane(GO:0031095)
0.0 0.4 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 0.4 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 3.4 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.3 GO:0001533 cornified envelope(GO:0001533)
0.0 0.5 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.4 GO:0030125 clathrin vesicle coat(GO:0030125)
0.0 0.2 GO:0035976 AP1 complex(GO:0035976)
0.0 0.3 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.5 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.2 GO:0036156 inner dynein arm(GO:0036156)
0.0 0.1 GO:1990745 EARP complex(GO:1990745)
0.0 0.4 GO:0032156 septin cytoskeleton(GO:0032156)
0.0 0.3 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.3 GO:0097542 ciliary tip(GO:0097542)
0.0 0.2 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 3.6 GO:0031256 leading edge membrane(GO:0031256)
0.0 0.1 GO:0031251 PAN complex(GO:0031251)
0.0 0.2 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.3 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0 2.2 GO:0019897 extrinsic component of plasma membrane(GO:0019897)
0.0 1.4 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.2 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.9 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.4 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.4 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.3 GO:0005922 connexon complex(GO:0005922)
0.0 0.4 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 1.0 GO:0031526 brush border membrane(GO:0031526)
0.0 0.4 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.2 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.1 GO:1990246 uniplex complex(GO:1990246)
0.0 0.8 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.1 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.1 GO:0045098 type III intermediate filament(GO:0045098)
0.0 0.3 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.1 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.0 GO:0044302 dentate gyrus mossy fiber(GO:0044302)
0.0 0.8 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.1 GO:0000801 central element(GO:0000801)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 2.9 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.9 2.7 GO:0004915 interleukin-6 receptor activity(GO:0004915) leukemia inhibitory factor receptor activity(GO:0004923) interleukin-6 binding(GO:0019981)
0.8 10.7 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.8 3.1 GO:0070976 TIR domain binding(GO:0070976)
0.5 1.9 GO:0042903 histone deacetylase activity (H4-K16 specific)(GO:0034739) tubulin deacetylase activity(GO:0042903)
0.4 3.7 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.4 1.8 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.3 1.8 GO:0071723 lipopeptide binding(GO:0071723)
0.3 2.0 GO:0046979 TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
0.3 2.0 GO:0005131 growth hormone receptor binding(GO:0005131)
0.3 2.8 GO:0051434 BH3 domain binding(GO:0051434)
0.3 1.6 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.3 0.8 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.2 0.7 GO:0046969 histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969)
0.2 0.7 GO:0016824 hydrolase activity, acting on acid halide bonds(GO:0016824) hydrolase activity, acting on acid halide bonds, in C-halide compounds(GO:0019120) alkylhalidase activity(GO:0047651)
0.2 0.7 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.2 1.6 GO:0042289 MHC class II protein binding(GO:0042289)
0.2 1.4 GO:0004064 arylesterase activity(GO:0004064)
0.2 3.2 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.2 1.8 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.2 0.8 GO:0042284 sphingolipid delta-4 desaturase activity(GO:0042284)
0.2 1.0 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.2 0.5 GO:0035877 death effector domain binding(GO:0035877)
0.2 0.5 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.2 0.7 GO:0034584 piRNA binding(GO:0034584)
0.2 0.7 GO:0048408 epidermal growth factor binding(GO:0048408)
0.2 0.5 GO:0005308 creatine transmembrane transporter activity(GO:0005308)
0.2 7.2 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.2 0.6 GO:0001847 opsonin receptor activity(GO:0001847)
0.2 0.5 GO:0004368 glycerol-3-phosphate dehydrogenase activity(GO:0004368) oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.2 0.8 GO:0046403 polynucleotide 3'-phosphatase activity(GO:0046403)
0.1 0.7 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.1 0.6 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.1 0.4 GO:0015140 malate transmembrane transporter activity(GO:0015140)
0.1 0.4 GO:0070905 serine binding(GO:0070905)
0.1 1.2 GO:0046977 TAP binding(GO:0046977)
0.1 1.3 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 0.1 GO:0004356 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211)
0.1 1.3 GO:0019992 diacylglycerol binding(GO:0019992)
0.1 0.8 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.1 1.1 GO:0097642 calcitonin family receptor activity(GO:0097642)
0.1 0.4 GO:0015142 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.1 3.4 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 0.9 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors(GO:0016661)
0.1 1.5 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 0.3 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.1 0.3 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.1 1.8 GO:0042605 peptide antigen binding(GO:0042605)
0.1 0.6 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.1 2.6 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.1 0.4 GO:0050632 propanoyl-CoA C-acyltransferase activity(GO:0033814) propionyl-CoA C2-trimethyltridecanoyltransferase activity(GO:0050632) phosphatidylethanolamine transporter activity(GO:1904121)
0.1 0.3 GO:0003880 protein C-terminal carboxyl O-methyltransferase activity(GO:0003880)
0.1 0.7 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.1 0.3 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.1 0.3 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.1 0.3 GO:0004471 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.1 0.6 GO:0004556 alpha-amylase activity(GO:0004556)
0.1 2.9 GO:0001968 fibronectin binding(GO:0001968)
0.1 2.3 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 0.3 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.1 0.8 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 0.4 GO:0051998 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719) carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.1 1.7 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 0.1 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.1 0.8 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.1 1.2 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 1.6 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.1 0.2 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.1 2.8 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 0.5 GO:0034711 inhibin binding(GO:0034711)
0.1 0.5 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.1 0.2 GO:0047710 bis(5'-adenosyl)-triphosphatase activity(GO:0047710)
0.1 0.9 GO:0043495 protein anchor(GO:0043495)
0.1 0.2 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.1 0.3 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.1 0.4 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.2 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.0 0.4 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.0 0.3 GO:0015288 porin activity(GO:0015288)
0.0 0.2 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.1 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.0 0.8 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.3 GO:0019865 immunoglobulin binding(GO:0019865)
0.0 0.2 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.0 5.2 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.6 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 1.0 GO:0047555 cGMP binding(GO:0030553) 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.3 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.1 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.0 0.3 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.3 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.8 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.6 GO:0045125 bioactive lipid receptor activity(GO:0045125)
0.0 0.5 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938) alpha-2A adrenergic receptor binding(GO:0031694)
0.0 4.3 GO:0005178 integrin binding(GO:0005178)
0.0 0.2 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.0 1.3 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.1 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 1.1 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.3 GO:0043262 adenosine-diphosphatase activity(GO:0043262)
0.0 0.7 GO:0031402 sodium ion binding(GO:0031402)
0.0 0.2 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.8 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.1 GO:0050436 microfibril binding(GO:0050436)
0.0 5.0 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.2 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.8 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.4 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0 1.7 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.6 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.1 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 0.4 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.3 GO:0051378 G-protein coupled serotonin receptor activity(GO:0004993) serotonin binding(GO:0051378)
0.0 0.3 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.0 0.8 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.5 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.2 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 1.7 GO:0000149 SNARE binding(GO:0000149)
0.0 0.2 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 1.0 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.1 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 2.1 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.1 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.3 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.1 GO:0015065 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0 3.0 GO:0005506 iron ion binding(GO:0005506)
0.0 0.7 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.1 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.3 GO:0005123 death receptor binding(GO:0005123)
0.0 0.4 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.2 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.1 GO:0034437 glycoprotein transporter activity(GO:0034437)
0.0 6.8 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.2 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.0 GO:0030284 estrogen receptor activity(GO:0030284)
0.0 0.1 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.3 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.4 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 6.0 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 0.1 GO:0046790 virion binding(GO:0046790)
0.0 0.4 GO:0005549 odorant binding(GO:0005549)
0.0 0.5 GO:0030552 cAMP binding(GO:0030552)
0.0 0.1 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.2 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.6 GO:0050699 WW domain binding(GO:0050699)
0.0 8.8 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.4 GO:0046965 retinoid X receptor binding(GO:0046965)
0.0 0.3 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 0.8 GO:0030507 spectrin binding(GO:0030507)
0.0 0.1 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.0 GO:0030116 glial cell-derived neurotrophic factor receptor binding(GO:0030116)
0.0 0.3 GO:0031489 myosin V binding(GO:0031489)
0.0 0.5 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.4 GO:0030145 manganese ion binding(GO:0030145)
0.0 0.0 GO:0004962 endothelin receptor activity(GO:0004962)
0.0 0.5 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.1 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.1 GO:0035198 miRNA binding(GO:0035198)
0.0 0.4 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.3 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 0.0 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.2 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 1.6 GO:0005125 cytokine activity(GO:0005125)
0.0 0.2 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 1.3 GO:0031072 heat shock protein binding(GO:0031072)
0.0 0.8 GO:0005254 chloride channel activity(GO:0005254)
0.0 0.3 GO:0042169 SH2 domain binding(GO:0042169)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 15.3 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.3 10.1 PID IL27 PATHWAY IL27-mediated signaling events
0.2 3.9 PID IL23 PATHWAY IL23-mediated signaling events
0.2 2.2 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.2 4.4 PID CONE PATHWAY Visual signal transduction: Cones
0.2 0.3 PID CD40 PATHWAY CD40/CD40L signaling
0.1 3.0 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1 5.2 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.1 2.7 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.1 1.3 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 5.2 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.1 3.3 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 2.4 PID S1P S1P1 PATHWAY S1P1 pathway
0.1 2.2 PID IL12 2PATHWAY IL12-mediated signaling events
0.1 4.7 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.1 0.7 ST STAT3 PATHWAY STAT3 Pathway
0.1 3.2 PID TNF PATHWAY TNF receptor signaling pathway
0.1 3.0 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.1 1.9 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 0.5 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 0.9 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 0.8 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 1.1 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.8 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 2.1 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 1.2 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.9 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 0.2 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 0.1 ST ADRENERGIC Adrenergic Pathway
0.0 2.3 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.1 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.7 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 1.0 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.2 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.1 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 0.3 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.4 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.4 PID ATM PATHWAY ATM pathway
0.0 0.2 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.3 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.3 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 1.1 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.3 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 0.9 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.4 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.3 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.6 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.4 PID IL4 2PATHWAY IL4-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 4.6 REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.3 3.9 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.3 5.2 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.3 1.8 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.3 10.7 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.2 9.9 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.2 1.2 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.2 1.5 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.2 2.8 REACTOME NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS Genes involved in Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
0.1 0.5 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.1 5.8 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 2.9 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.1 3.0 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.1 2.9 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.1 3.1 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 0.5 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 1.4 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 0.9 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 2.4 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 0.7 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 0.5 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 1.3 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.1 1.1 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.1 1.0 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.3 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 1.5 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.1 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 1.4 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.8 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.7 REACTOME SHC MEDIATED SIGNALLING Genes involved in SHC-mediated signalling
0.0 1.0 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.7 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.7 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 2.2 REACTOME TRANS GOLGI NETWORK VESICLE BUDDING Genes involved in trans-Golgi Network Vesicle Budding
0.0 0.3 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.3 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 1.3 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.3 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.3 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 1.2 REACTOME REGULATION OF INSULIN SECRETION Genes involved in Regulation of Insulin Secretion
0.0 0.5 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.9 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.2 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.8 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.4 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.4 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.1 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.4 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0 0.6 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.4 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.9 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.5 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 3.3 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 0.1 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.8 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.3 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.2 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.1 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.3 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.2 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 1.3 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.0 0.1 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG