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12D miR HR13_24

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Results for Ptf1a

Z-value: 0.57

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Transcription factors associated with Ptf1a

Gene Symbol Gene ID Gene Info
ENSMUSG00000026735.2 pancreas specific transcription factor, 1a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Ptf1amm10_v2_chr2_+_19445632_194456630.766.9e-03Click!

Activity profile of Ptf1a motif

Sorted Z-values of Ptf1a motif

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_41392356 0.83 ENSMUST00000049079.7
predicted gene 5771
chr7_-_131322292 0.74 ENSMUST00000046611.7
CUB and zona pellucida-like domains 1
chr6_-_41314700 0.67 ENSMUST00000064324.5
trypsin 5
chr7_+_28540863 0.61 ENSMUST00000119180.2
syncollin
chr15_-_76616841 0.54 ENSMUST00000073428.5
solute carrier family 39 (zinc transporter), member 4
chr6_+_41354105 0.51 ENSMUST00000072103.5
trypsin 10
chr15_-_77399086 0.51 ENSMUST00000175919.1
ENSMUST00000176074.1
apolipoprotein L 7a
chr6_+_41302265 0.43 ENSMUST00000031913.4
trypsin 4
chr11_+_4031770 0.37 ENSMUST00000019512.7
SEC14-like 4 (S. cerevisiae)
chr6_+_41458923 0.34 ENSMUST00000031910.7
protease, serine, 1 (trypsin 1)
chr4_-_64046925 0.33 ENSMUST00000107377.3
tenascin C
chr4_-_118544010 0.26 ENSMUST00000128098.1
transmembrane protein 125
chr2_+_180725263 0.24 ENSMUST00000094218.3
solute carrier family 17, member 9
chrX_+_101383726 0.23 ENSMUST00000119190.1
gap junction protein, beta 1
chr17_+_47769191 0.22 ENSMUST00000160373.1
ENSMUST00000159641.1
transcription factor EB
chrX_+_160390684 0.21 ENSMUST00000112408.2
ENSMUST00000112402.1
ENSMUST00000112401.1
ENSMUST00000112400.1
ENSMUST00000112405.2
ENSMUST00000112404.2
ENSMUST00000146805.1
G protein-coupled receptor 64
chrX_-_162964557 0.19 ENSMUST00000038769.2
S100 calcium binding protein G
chr4_+_115088708 0.18 ENSMUST00000171877.1
ENSMUST00000177647.1
ENSMUST00000106548.2
ENSMUST00000030488.2
PDZK1 interacting protein 1
chr5_+_149439706 0.18 ENSMUST00000031667.4
testis expressed 26
chr7_+_118600152 0.17 ENSMUST00000121744.1
transmembrane channel-like gene family 5
chr11_+_66957894 0.17 ENSMUST00000127166.1
RIKEN cDNA 9130409J20 gene
chr8_-_79248537 0.14 ENSMUST00000034109.4
RIKEN cDNA 1700011L22 gene
chr7_-_79842287 0.14 ENSMUST00000049004.6
alanyl (membrane) aminopeptidase
chr7_+_30458280 0.14 ENSMUST00000126297.1
nephrosis 1, nephrin
chr6_-_69243445 0.14 ENSMUST00000101325.3
immunoglobulin kappa chain variable 4-71
chr7_-_127725616 0.13 ENSMUST00000076091.2
cardiotrophin 2
chr11_+_120633719 0.13 ENSMUST00000181502.1
predicted gene, 17586
chr5_+_64970069 0.12 ENSMUST00000031080.8
family with sequence similarity 114, member A1
chr4_+_155839675 0.12 ENSMUST00000141883.1
matrix-remodelling associated 8
chr3_-_83841767 0.12 ENSMUST00000029623.9
toll-like receptor 2
chr7_-_4532419 0.11 ENSMUST00000094897.4
dynein, axonemal assembly factor 3
chr9_-_106476372 0.11 ENSMUST00000123555.1
ENSMUST00000125850.1
poly (ADP-ribose) polymerase family, member 3
chr14_-_70207637 0.11 ENSMUST00000022682.5
sorbin and SH3 domain containing 3
chr6_-_5256226 0.11 ENSMUST00000125686.1
ENSMUST00000031773.2
paraoxonase 3
chr2_-_131175201 0.11 ENSMUST00000110218.2
sperm flagellar 1
chr4_-_155010984 0.10 ENSMUST00000105631.2
ENSMUST00000139976.2
ENSMUST00000145662.2
phospholipase C, eta 2
chr19_+_16435616 0.10 ENSMUST00000025602.2
guanine nucleotide binding protein, alpha 14
chr9_-_112187898 0.10 ENSMUST00000178410.1
ENSMUST00000172380.3
cyclic AMP-regulated phosphoprotein, 21
chr3_-_141931523 0.09 ENSMUST00000106232.1
bone morphogenetic protein receptor, type 1B
chr5_-_109297556 0.09 ENSMUST00000167133.1
vomeronasal 2, receptor 15
chr11_+_120608469 0.09 ENSMUST00000106194.1
ENSMUST00000106195.2
neuropeptide B
chr2_+_26973416 0.09 ENSMUST00000014996.7
ENSMUST00000102891.3
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 13
chr11_+_66956620 0.09 ENSMUST00000150220.1
RIKEN cDNA 9130409J20 gene
chr1_-_171607321 0.09 ENSMUST00000111277.1
ENSMUST00000004827.7
lymphocyte antigen 9
chr11_+_101325063 0.08 ENSMUST00000041095.7
ENSMUST00000107264.1
amine oxidase, copper containing 2 (retina-specific)
chr9_-_108305941 0.08 ENSMUST00000044725.7
T cell leukemia translocation altered gene
chr9_-_108597558 0.07 ENSMUST00000006853.5
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
chr9_-_106476590 0.07 ENSMUST00000112479.2
poly (ADP-ribose) polymerase family, member 3
chr11_-_118355496 0.07 ENSMUST00000017610.3
tissue inhibitor of metalloproteinase 2
chr11_+_82911253 0.07 ENSMUST00000164945.1
ENSMUST00000018989.7
unc-45 homolog B (C. elegans)
chr2_+_22227503 0.06 ENSMUST00000044749.7
myosin IIIA
chr5_-_66054499 0.06 ENSMUST00000145625.1
RNA binding motif protein 47
chr1_-_171607378 0.06 ENSMUST00000068878.7
lymphocyte antigen 9
chr10_+_60346851 0.06 ENSMUST00000020301.7
ENSMUST00000105460.1
ENSMUST00000170507.1
RIKEN cDNA 4632428N05 gene
chr8_-_120177440 0.06 ENSMUST00000048786.6
family with sequence similarity 92, member B
chr11_-_96916407 0.06 ENSMUST00000130774.1
CDK5 regulatory subunit associated protein 3
chr11_-_99155067 0.06 ENSMUST00000103134.3
chemokine (C-C motif) receptor 7
chr17_+_69383768 0.06 ENSMUST00000112676.2
zinc finger and BTB domain containing 14
chr3_+_138277489 0.05 ENSMUST00000004232.9
alcohol dehydrogenase 1 (class I)
chr7_-_144582392 0.05 ENSMUST00000033394.7
Fas (TNFRSF6)-associated via death domain
chr11_-_109611417 0.05 ENSMUST00000103060.3
ENSMUST00000047186.3
ENSMUST00000106689.1
WD repeat domain, phosphoinositide interacting 1
chr7_+_18065929 0.05 ENSMUST00000032520.2
ENSMUST00000108487.2
ENSMUST00000108483.1
carcinoembryonic antigen-related cell adhesion molecule 12
chr11_-_100441058 0.05 ENSMUST00000107399.2
ENSMUST00000092688.5
5'-nucleotidase, cytosolic IIIB
chr6_+_65590382 0.05 ENSMUST00000114236.1
TNFAIP3 interacting protein 3
chr11_-_100441006 0.05 ENSMUST00000092689.2
5'-nucleotidase, cytosolic IIIB
chr4_-_136835843 0.05 ENSMUST00000105846.2
ENSMUST00000059287.7
ENSMUST00000105845.2
Eph receptor B2
chr11_-_100440928 0.05 ENSMUST00000107397.1
5'-nucleotidase, cytosolic IIIB
chr1_+_92910805 0.05 ENSMUST00000179711.1
arginyl aminopeptidase (aminopeptidase B)-like 1
chr15_-_79774408 0.04 ENSMUST00000023055.6
dynein, axonemal, light chain 4
chr11_-_102185202 0.04 ENSMUST00000107156.2
LSM12 homolog (S. cerevisiae)
chr19_+_9982694 0.04 ENSMUST00000025563.6
ferritin heavy chain 1
chr5_+_114314941 0.04 ENSMUST00000124316.1
ENSMUST00000169347.1
myosin 1H
chr4_+_152297205 0.04 ENSMUST00000048892.7
isoprenylcysteine carboxyl methyltransferase
chr2_-_7395968 0.04 ENSMUST00000002176.6
CUGBP, Elav-like family member 2
chr9_-_85749308 0.04 ENSMUST00000039213.8
inhibitor of Bruton agammaglobulinemia tyrosine kinase
chr8_+_81342556 0.04 ENSMUST00000172167.1
ENSMUST00000169116.1
ENSMUST00000109852.2
ENSMUST00000172031.1
inositol polyphosphate-4-phosphatase, type II
chr11_-_96916448 0.04 ENSMUST00000103152.4
CDK5 regulatory subunit associated protein 3
chr8_+_83290342 0.03 ENSMUST00000034146.3
uncoupling protein 1 (mitochondrial, proton carrier)
chr3_-_108445183 0.03 ENSMUST00000090553.5
ENSMUST00000153499.1
seryl-aminoacyl-tRNA synthetase
chr8_-_120177420 0.03 ENSMUST00000135567.2
family with sequence similarity 92, member B
chr11_+_97315716 0.03 ENSMUST00000019026.3
ENSMUST00000132168.1
mitochondrial ribosomal protein L45
chr11_-_96916366 0.03 ENSMUST00000144731.1
ENSMUST00000127048.1
CDK5 regulatory subunit associated protein 3
chr15_-_79774383 0.03 ENSMUST00000069877.5
dynein, axonemal, light chain 4
chr11_+_120608492 0.03 ENSMUST00000061309.4
neuropeptide B
chr11_-_102185239 0.03 ENSMUST00000021297.5
LSM12 homolog (S. cerevisiae)
chr14_+_75845093 0.03 ENSMUST00000110894.2
tumor protein, translationally-controlled 1
chr11_+_86484647 0.03 ENSMUST00000020827.6
ring finger protein, transmembrane 1
chr1_+_20951666 0.03 ENSMUST00000038447.4
EF-hand domain (C-terminal) containing 1
chr14_-_105176860 0.03 ENSMUST00000163545.1
RNA binding motif protein 26
chr4_-_88438900 0.03 ENSMUST00000132493.1
ENSMUST00000030221.2
ENSMUST00000151280.1
protein tyrosine phosphatase-like A domain containing 2
chr1_+_92910758 0.03 ENSMUST00000027487.8
arginyl aminopeptidase (aminopeptidase B)-like 1
chr2_-_125782834 0.03 ENSMUST00000053699.6
SECIS binding protein 2-like
chr11_+_118443471 0.03 ENSMUST00000133558.1
C1q and tumor necrosis factor related protein 1
chr18_+_37477768 0.03 ENSMUST00000051442.5
protocadherin beta 16
chr12_+_112760652 0.03 ENSMUST00000063888.3
phospholipase D family, member 4
chr17_+_69383319 0.02 ENSMUST00000062369.7
zinc finger and BTB domain containing 14
chr18_+_34331132 0.02 ENSMUST00000072576.3
ENSMUST00000119329.1
signal recognition particle 19
chr7_+_19131686 0.02 ENSMUST00000165913.1
F-box protein 46
chr7_-_13054514 0.02 ENSMUST00000182087.1
myeloid zinc finger 1
chr10_-_95417099 0.02 ENSMUST00000135822.1
suppressor of cytokine signaling 2
chr11_+_49247462 0.02 ENSMUST00000109194.1
mannoside acetylglucosaminyltransferase 1
chr11_-_103344651 0.02 ENSMUST00000041385.7
Rho GTPase activating protein 27
chr11_+_40733639 0.02 ENSMUST00000020578.4
NudC domain containing 2
chr11_-_90390895 0.02 ENSMUST00000004051.7
hepatic leukemia factor
chr17_-_27513341 0.02 ENSMUST00000118161.1
glutamate receptor, metabotropic 4
chr11_-_70322520 0.02 ENSMUST00000019051.2
arachidonate lipoxygenase, epidermal
chr10_+_42678890 0.02 ENSMUST00000040718.5
osteopetrosis associated transmembrane protein 1
chr9_-_77399308 0.01 ENSMUST00000183878.1
RP23-264N13.2
chr5_-_120887582 0.01 ENSMUST00000086368.5
2'-5' oligoadenylate synthetase 1G
chr9_+_123021315 0.01 ENSMUST00000084733.5
transmembrane protein 42
chr7_-_140102367 0.01 ENSMUST00000142105.1
fucose mutarotase
chr12_-_113307912 0.01 ENSMUST00000103418.1
immunoglobulin heavy constant gamma 2B
chr4_-_12087912 0.01 ENSMUST00000050686.3
transmembrane protein 67
chr11_-_6444352 0.01 ENSMUST00000093346.5
ENSMUST00000109737.2
H2A histone family, member V
chr14_-_63417125 0.00 ENSMUST00000014597.3
B lymphoid kinase
chr17_-_28517509 0.00 ENSMUST00000114792.1
ENSMUST00000177939.1
FK506 binding protein 5
chr14_-_118925314 0.00 ENSMUST00000004055.8
DAZ interacting protein 1
chr8_-_105295934 0.00 ENSMUST00000057855.3
exocyst complex component 3-like
chr14_-_55944536 0.00 ENSMUST00000022834.6
chymase 1, mast cell
chr2_+_25500750 0.00 ENSMUST00000015239.3
F-box and WD-40 domain protein 5
chr7_-_25718976 0.00 ENSMUST00000002683.2
coiled-coil domain containing 97
chr1_+_36471590 0.00 ENSMUST00000153128.1
cyclin M4
chr1_+_36691487 0.00 ENSMUST00000081180.4
cytochrome c oxidase subunit Vb

Network of associatons between targets according to the STRING database.

First level regulatory network of Ptf1a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
0.1 0.3 GO:0060447 peripheral nervous system axon regeneration(GO:0014012) bud outgrowth involved in lung branching(GO:0060447)
0.1 0.2 GO:1990166 protein localization to site of double-strand break(GO:1990166)
0.1 0.2 GO:1902477 defense response to bacterium, incompatible interaction(GO:0009816) regulation of defense response to bacterium, incompatible interaction(GO:1902477)
0.0 0.1 GO:0052572 cell surface pattern recognition receptor signaling pathway(GO:0002752) positive regulation of interleukin-18 production(GO:0032741) response to immune response of other organism involved in symbiotic interaction(GO:0052564) response to host immune response(GO:0052572) detection of bacterial lipopeptide(GO:0070340) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.0 0.1 GO:0009804 coumarin metabolic process(GO:0009804) phenylpropanoid catabolic process(GO:0046271)
0.0 0.1 GO:0060857 establishment of glial blood-brain barrier(GO:0060857)
0.0 0.2 GO:0015868 purine ribonucleotide transport(GO:0015868)
0.0 2.8 GO:0007586 digestion(GO:0007586)
0.0 0.1 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.0 0.1 GO:0097021 lymphocyte migration into lymphoid organs(GO:0097021) regulation of thymocyte migration(GO:2000410) positive regulation of thymocyte migration(GO:2000412) regulation of dendritic cell dendrite assembly(GO:2000547)
0.0 0.1 GO:2000451 positive regulation of CD8-positive, alpha-beta T cell extravasation(GO:2000451)
0.0 0.1 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.1 GO:0072675 osteoclast fusion(GO:0072675)
0.0 0.1 GO:0071569 protein ufmylation(GO:0071569)
0.0 0.1 GO:0006069 ethanol oxidation(GO:0006069)
0.0 0.0 GO:1904046 seryl-tRNA aminoacylation(GO:0006434) negative regulation of vascular endothelial growth factor production(GO:1904046)
0.0 0.1 GO:1905049 negative regulation of metallopeptidase activity(GO:1905049)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.3 GO:0005614 interstitial matrix(GO:0005614)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:0045545 syndecan binding(GO:0045545)
0.0 0.1 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.0 0.2 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.1 GO:0052594 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.0 0.2 GO:0003909 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 0.1 GO:0071723 lipopeptide binding(GO:0071723)
0.0 0.1 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0 0.1 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 2.7 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.2 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.1 GO:0035877 death effector domain binding(GO:0035877)
0.0 0.0 GO:0004828 serine-tRNA ligase activity(GO:0004828)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.1 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.2 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.3 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix