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12D miR HR13_24

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Results for Fos

Z-value: 0.67

Motif logo

Transcription factors associated with Fos

Gene Symbol Gene ID Gene Info
ENSMUSG00000021250.7 FBJ osteosarcoma oncogene

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Fosmm10_v2_chr12_+_85473883_85473896-0.058.8e-01Click!

Activity profile of Fos motif

Sorted Z-values of Fos motif

Promoter Log-likelihood Transcript Gene Gene Info
chr9_+_7347374 0.88 ENSMUST00000065079.5
ENSMUST00000005950.5
matrix metallopeptidase 12
chr6_+_65590382 0.80 ENSMUST00000114236.1
TNFAIP3 interacting protein 3
chr2_+_24336846 0.80 ENSMUST00000114487.2
interleukin 1 receptor antagonist
chr6_+_49036518 0.77 ENSMUST00000031840.7
glycoprotein (transmembrane) nmb
chr13_-_56296551 0.69 ENSMUST00000021970.9
chemokine (C-X-C motif) ligand 14
chr14_+_65968483 0.63 ENSMUST00000022616.6
clusterin
chr4_+_118527229 0.58 ENSMUST00000030261.5
RIKEN cDNA 2610528J11 gene
chr4_+_118526986 0.58 ENSMUST00000106367.1
RIKEN cDNA 2610528J11 gene
chr7_+_141079759 0.57 ENSMUST00000066873.4
ENSMUST00000163041.1
plakophilin 3
chr1_+_107511489 0.55 ENSMUST00000064916.2
serine (or cysteine) peptidase inhibitor, clade B, member 2
chr10_+_97482350 0.54 ENSMUST00000163448.2
decorin
chr1_+_107511416 0.53 ENSMUST00000009356.4
serine (or cysteine) peptidase inhibitor, clade B, member 2
chr14_-_41185188 0.52 ENSMUST00000077136.3
surfactant associated protein D
chr11_+_50357759 0.51 ENSMUST00000052596.2
chibby homolog 3 (Drosophila)
chr2_+_13573927 0.49 ENSMUST00000141365.1
ENSMUST00000028062.2
vimentin
chr11_+_61065798 0.48 ENSMUST00000041944.2
ENSMUST00000108717.2
potassium inwardly-rectifying channel, subfamily J, member 12
chr7_+_128129536 0.48 ENSMUST00000033053.6
integrin alpha X
chr6_-_129507107 0.48 ENSMUST00000183258.1
ENSMUST00000182784.1
ENSMUST00000032265.6
ENSMUST00000162815.1
oxidized low density lipoprotein (lectin-like) receptor 1
chr4_-_127358124 0.46 ENSMUST00000046498.2
gap junction protein, beta 5
chr5_+_30013141 0.43 ENSMUST00000026845.7
interleukin 6
chr4_+_43506966 0.43 ENSMUST00000030183.3
carbonic anhydrase 9
chr11_-_100207507 0.42 ENSMUST00000007272.7
keratin 14
chr7_+_27486910 0.42 ENSMUST00000008528.7
SERTA domain containing 1
chr15_-_9529868 0.39 ENSMUST00000003981.4
interleukin 7 receptor
chr7_-_4971168 0.39 ENSMUST00000133272.1
predicted gene 1078
chr14_+_103513328 0.38 ENSMUST00000095576.3
sciellin
chr9_+_7692086 0.36 ENSMUST00000018767.7
matrix metallopeptidase 7
chr11_-_100261021 0.36 ENSMUST00000080893.6
keratin 17
chrX_+_159840463 0.35 ENSMUST00000112451.1
ENSMUST00000112453.2
SH3-domain kinase binding protein 1
chr7_+_19083842 0.34 ENSMUST00000032568.7
ENSMUST00000122999.1
ENSMUST00000108473.3
ENSMUST00000108474.1
dystrophia myotonica-protein kinase
chr1_-_153186447 0.33 ENSMUST00000027753.6
laminin, gamma 2
chrX_-_167209149 0.32 ENSMUST00000112176.1
thymosin, beta 4, X chromosome
chr11_+_82045705 0.32 ENSMUST00000021011.2
chemokine (C-C motif) ligand 7
chr2_-_25196759 0.31 ENSMUST00000081869.6
torsin family 4, member A
chr2_+_52038005 0.31 ENSMUST00000065927.5
tumor necrosis factor alpha induced protein 6
chr19_+_5877794 0.31 ENSMUST00000145200.1
ENSMUST00000025732.7
ENSMUST00000125114.1
ENSMUST00000155697.1
solute carrier family 25, member 45
chr10_-_64090265 0.30 ENSMUST00000105439.1
leucine rich repeat transmembrane neuronal 3
chr1_-_171437288 0.30 ENSMUST00000181499.1
predicted gene, 26641
chr2_-_18048784 0.30 ENSMUST00000142856.1
SKI/DACH domain containing 1
chr7_-_44816586 0.29 ENSMUST00000047356.8
activating transcription factor 5
chr9_+_69453620 0.29 ENSMUST00000034756.8
ENSMUST00000123470.1
annexin A2
chrX_-_134583114 0.29 ENSMUST00000113213.1
ENSMUST00000033617.6
Bruton agammaglobulinemia tyrosine kinase
chr3_+_89421619 0.27 ENSMUST00000094378.3
ENSMUST00000137793.1
src homology 2 domain-containing transforming protein C1
chr10_-_44004846 0.27 ENSMUST00000020017.8
absent in melanoma 1
chr11_+_61684419 0.26 ENSMUST00000093019.5
family with sequence similarity 83, member G
chr2_-_29253001 0.26 ENSMUST00000071201.4
netrin G2
chr16_+_32400506 0.26 ENSMUST00000115149.2
transmembrane 4 L six family member 19
chrX_-_48454152 0.26 ENSMUST00000114958.1
E74-like factor 4 (ets domain transcription factor)
chr10_+_119992962 0.26 ENSMUST00000154238.1
glutamate receptor interacting protein 1
chr6_-_122856151 0.25 ENSMUST00000042081.8
complement component 3a receptor 1
chr7_+_78913765 0.25 ENSMUST00000038142.8
interferon-stimulated protein
chr1_-_182517447 0.25 ENSMUST00000068505.8
calpain 2
chr6_+_53573364 0.25 ENSMUST00000047450.7
cAMP responsive element binding protein 5
chr10_+_119992916 0.24 ENSMUST00000105261.2
glutamate receptor interacting protein 1
chr16_+_17561885 0.24 ENSMUST00000171002.1
ENSMUST00000023441.4
purinergic receptor P2X, ligand-gated ion channel, 6
chr10_-_76725978 0.24 ENSMUST00000001147.4
collagen, type VI, alpha 1
chr13_+_15463837 0.23 ENSMUST00000110510.3
GLI-Kruppel family member GLI3
chr8_+_69902178 0.23 ENSMUST00000050373.5
testis-specific serine kinase 6
chr7_+_78914216 0.23 ENSMUST00000120331.2
interferon-stimulated protein
chr15_+_102503722 0.22 ENSMUST00000096145.4
predicted gene 10337
chr9_-_119977250 0.22 ENSMUST00000035101.7
cysteine-serine-rich nuclear protein 1
chr4_-_140665891 0.22 ENSMUST00000069623.5
Rho guanine nucleotide exchange factor (GEF) 10-like
chr4_-_62434722 0.22 ENSMUST00000107454.1
ring finger protein 183
chr7_-_31042078 0.22 ENSMUST00000162116.1
ENSMUST00000159924.1
ENSMUST00000159753.1
ENSMUST00000160689.1
ENSMUST00000162733.1
ENSMUST00000162087.1
ENSMUST00000009831.7
FXYD domain-containing ion transport regulator 5
chr1_+_171559186 0.22 ENSMUST00000004829.7
CD244 natural killer cell receptor 2B4
chr6_-_129533267 0.22 ENSMUST00000181594.1
RIKEN cDNA 1700101I11 gene
chr7_+_141079125 0.21 ENSMUST00000159375.1
plakophilin 3
chr7_+_126584937 0.21 ENSMUST00000039522.6
apolipoprotein B receptor
chr17_+_47769191 0.21 ENSMUST00000160373.1
ENSMUST00000159641.1
transcription factor EB
chr2_-_34958129 0.21 ENSMUST00000172159.1
TNF receptor-associated factor 1
chr11_-_93968293 0.21 ENSMUST00000170303.1
predicted gene 20390
chr10_+_26078255 0.21 ENSMUST00000041011.3
predicted gene 9767
chr7_-_143502515 0.21 ENSMUST00000010904.4
pleckstrin homology-like domain, family A, member 2
chr10_-_19015347 0.20 ENSMUST00000019997.4
tumor necrosis factor, alpha-induced protein 3
chr17_+_70561739 0.20 ENSMUST00000097288.2
discs, large (Drosophila) homolog-associated protein 1
chr9_+_114978507 0.20 ENSMUST00000183104.1
oxysterol binding protein-like 10
chr13_+_95696851 0.20 ENSMUST00000022182.4
coagulation factor II (thrombin) receptor-like 2
chr17_+_78508063 0.19 ENSMUST00000024880.9
vitrin
chr10_+_128790903 0.19 ENSMUST00000026411.6
matrix metallopeptidase 19
chr7_+_30763750 0.18 ENSMUST00000165887.1
ENSMUST00000085691.4
ENSMUST00000085688.4
ENSMUST00000054427.6
dermokine
chr2_-_101797650 0.18 ENSMUST00000141814.1
ENSMUST00000171088.1
ENSMUST00000043845.7
proline rich 5 like
chr19_+_8850785 0.18 ENSMUST00000096257.2
LRRN4 C-terminal like
chr6_-_35326123 0.18 ENSMUST00000051176.7
family with sequence similarity 180, member A
chr11_+_116531744 0.18 ENSMUST00000106387.2
ENSMUST00000100201.3
sphingosine kinase 1
chr11_+_78188737 0.18 ENSMUST00000108322.2
RAB34, member of RAS oncogene family
chr15_+_80255184 0.17 ENSMUST00000109605.3
activating transcription factor 4
chr7_-_142372342 0.17 ENSMUST00000059223.8
interferon induced transmembrane protein 10
chr3_+_100825452 0.17 ENSMUST00000054791.7
V-set domain containing T cell activation inhibitor 1
chr11_+_78188806 0.17 ENSMUST00000056241.5
RAB34, member of RAS oncogene family
chr15_+_54571358 0.17 ENSMUST00000025356.2
mal, T cell differentiation protein 2
chr1_+_55052770 0.17 ENSMUST00000027125.5
ENSMUST00000087617.4
coenzyme Q10 homolog B (S. cerevisiae)
chr17_+_45555693 0.17 ENSMUST00000024742.7
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, epsilon
chr10_+_21993890 0.17 ENSMUST00000092673.4
serum/glucocorticoid regulated kinase 1
chr2_+_25395866 0.17 ENSMUST00000028328.2
ectonucleoside triphosphate diphosphohydrolase 2
chr4_+_150927918 0.17 ENSMUST00000139826.1
ENSMUST00000116257.1
tumor necrosis factor receptor superfamily, member 9
chr4_-_133602168 0.17 ENSMUST00000057311.3
stratifin
chr8_-_25091341 0.17 ENSMUST00000125466.1
pleckstrin homology domain-containing, family A (phosphoinositide binding specific) member 2
chr14_-_54712139 0.17 ENSMUST00000064290.6
CCAAT/enhancer binding protein (C/EBP), epsilon
chr7_-_31041777 0.16 ENSMUST00000161805.1
FXYD domain-containing ion transport regulator 5
chr11_+_9118070 0.16 ENSMUST00000020677.1
ENSMUST00000101525.2
ENSMUST00000170444.1
uridine phosphorylase 1
chr8_+_119437118 0.16 ENSMUST00000152420.1
ENSMUST00000098365.3
oxidative stress induced growth inhibitor 1
chr14_+_79515618 0.16 ENSMUST00000110835.1
E74-like factor 1
chrX_+_71962971 0.16 ENSMUST00000048790.6
proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane)
chr15_-_103366763 0.16 ENSMUST00000023128.6
integrin alpha 5 (fibronectin receptor alpha)
chr8_+_88289028 0.16 ENSMUST00000171456.1
adenylate cyclase 7
chr6_+_92940572 0.16 ENSMUST00000181145.1
ENSMUST00000181840.1
RIKEN cDNA 9530026P05 gene
chr3_-_107518001 0.16 ENSMUST00000169449.1
ENSMUST00000029499.8
solute carrier family 6 (neurotransmitter transporter), member 17
chr7_-_126369543 0.15 ENSMUST00000032997.6
linker for activation of T cells
chr6_+_29529277 0.15 ENSMUST00000163511.1
interferon regulatory factor 5
chr16_-_30283251 0.15 ENSMUST00000064606.7
leucine rich repeat containing 15
chr11_+_78188422 0.15 ENSMUST00000002128.7
ENSMUST00000150941.1
RAB34, member of RAS oncogene family
chr4_-_133212480 0.15 ENSMUST00000052090.8
G-protein coupled receptor 3
chr17_-_47834682 0.15 ENSMUST00000066368.6
MyoD family inhibitor
chr14_-_12345847 0.14 ENSMUST00000022262.4
Fez family zinc finger 2
chr1_+_131962941 0.14 ENSMUST00000177943.1
solute carrier family 45, member 3
chr2_+_30078584 0.14 ENSMUST00000045246.7
protein kinase N3
chr11_-_69666062 0.14 ENSMUST00000108654.2
ENSMUST00000018918.5
CD68 antigen
chr6_+_135362931 0.14 ENSMUST00000032330.9
epithelial membrane protein 1
chr5_+_117363513 0.14 ENSMUST00000111959.1
WD repeat and SOCS box-containing 2
chr3_+_102469918 0.14 ENSMUST00000106925.2
ENSMUST00000035952.3
nerve growth factor
chr17_+_26113286 0.14 ENSMUST00000025010.7
transmembrane protein 8 (five membrane-spanning domains)
chr1_+_106861144 0.14 ENSMUST00000086701.6
ENSMUST00000112730.1
serine (or cysteine) peptidase inhibitor, clade B, member 5
chr15_-_102257306 0.14 ENSMUST00000135466.1
retinoic acid receptor, gamma
chr9_+_44240668 0.14 ENSMUST00000092426.3
coiled-coil domain containing 153
chr7_+_30776394 0.14 ENSMUST00000041703.7
dermokine
chr1_+_109993982 0.14 ENSMUST00000027542.6
cadherin 7, type 2
chr5_-_93045022 0.14 ENSMUST00000061328.5
sosondowah ankyrin repeat domain family member B
chrX_+_6047453 0.13 ENSMUST00000103007.3
nudix (nucleoside diphosphate linked moiety X)-type motif 11
chr3_+_103576081 0.13 ENSMUST00000183637.1
ENSMUST00000117221.2
ENSMUST00000118117.1
ENSMUST00000118563.2
synaptotagmin VI
chr18_+_35118880 0.13 ENSMUST00000042345.6
catenin (cadherin associated protein), alpha 1
chrX_-_101222426 0.13 ENSMUST00000120389.1
ENSMUST00000156473.1
ENSMUST00000077876.3
sorting nexin 12
chr12_+_10369967 0.13 ENSMUST00000118657.1
ENSMUST00000143739.1
ENSMUST00000002456.8
5'-nucleotidase, cytosolic IB
chr19_+_46305682 0.13 ENSMUST00000111881.2
nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100
chr2_+_160880642 0.13 ENSMUST00000109456.2
lipin 3
chr7_+_139834148 0.13 ENSMUST00000026548.7
G protein-coupled receptor 123
chr10_+_26772477 0.13 ENSMUST00000039557.7
Rho GTPase activating protein 18
chr11_-_84067063 0.13 ENSMUST00000108101.1
dual specificity phosphatase 14
chr7_-_81454751 0.12 ENSMUST00000098331.3
ENSMUST00000178892.1
cytoplasmic polyadenylation element binding protein 1
chr19_-_34166037 0.12 ENSMUST00000025686.7
ankyrin repeat domain 22
chr7_-_45920830 0.12 ENSMUST00000164119.1
epithelial membrane protein 3
chr4_-_140774196 0.12 ENSMUST00000026381.6
peptidyl arginine deiminase, type IV
chr11_-_106973090 0.12 ENSMUST00000150366.1
predicted gene 11707
chr2_+_174760781 0.12 ENSMUST00000140908.1
endothelin 3
chr9_+_108953578 0.12 ENSMUST00000112070.1
collagen, type VII, alpha 1
chr6_-_124769548 0.12 ENSMUST00000149652.1
ENSMUST00000112476.1
ENSMUST00000004378.8
enolase 2, gamma neuronal
chr15_+_101473472 0.11 ENSMUST00000088049.3
keratin 86
chr16_-_85173692 0.11 ENSMUST00000005406.10
amyloid beta (A4) precursor protein
chr11_-_23519181 0.11 ENSMUST00000020527.5
RIKEN cDNA 1700093K21 gene
chr3_+_14641722 0.11 ENSMUST00000029071.8
carbonic anhydrase 13
chr7_-_29168647 0.11 ENSMUST00000048923.6
sprouty-related, EVH1 domain containing 3
chr11_+_95842283 0.11 ENSMUST00000107714.2
ENSMUST00000107711.1
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
chr5_+_100846130 0.11 ENSMUST00000112887.1
ENSMUST00000031255.8
1-acylglycerol-3-phosphate O-acyltransferase 9
chr16_-_92826004 0.11 ENSMUST00000023673.7
runt related transcription factor 1
chr2_-_77703252 0.11 ENSMUST00000171063.1
zinc finger protein 385B
chr5_-_122502192 0.11 ENSMUST00000179939.1
ENSMUST00000177974.1
ENSMUST00000031423.8
ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
chrX_-_143827391 0.11 ENSMUST00000087316.5
calpain 6
chr3_-_88177671 0.11 ENSMUST00000181837.1
RIKEN cDNA 1700113A16 gene
chr19_-_58455903 0.10 ENSMUST00000131877.1
glial cell line derived neurotrophic factor family receptor alpha 1
chr11_-_116024489 0.10 ENSMUST00000016703.7
H3 histone, family 3B
chr11_-_69880971 0.10 ENSMUST00000050555.3
potassium channel tetramerisation domain containing 11
chr3_-_95739544 0.10 ENSMUST00000153026.1
ENSMUST00000123143.1
ENSMUST00000137912.1
ENSMUST00000029753.6
ENSMUST00000131376.1
ENSMUST00000117507.2
ENSMUST00000128885.1
ENSMUST00000147217.1
extracellular matrix protein 1
chr10_-_128298084 0.10 ENSMUST00000026449.1
interleukin 23, alpha subunit p19
chr1_-_156034800 0.10 ENSMUST00000169241.1
torsin A interacting protein 1
chr7_-_102250086 0.10 ENSMUST00000106923.1
ENSMUST00000098230.4
ras homolog gene family, member G
chr6_-_83070225 0.10 ENSMUST00000174674.1
ENSMUST00000089641.3
T cell leukemia, homeobox 2
chr11_+_94327984 0.10 ENSMUST00000107818.2
ENSMUST00000051221.6
ankyrin repeat domain 40
chr11_-_99322943 0.10 ENSMUST00000038004.2
keratin 25
chr10_-_128498676 0.10 ENSMUST00000026428.3
myosin, light polypeptide 6B
chr11_-_84069179 0.10 ENSMUST00000138208.1
dual specificity phosphatase 14
chr17_+_46161021 0.10 ENSMUST00000024748.7
ENSMUST00000172170.1
GTP binding protein 2
chr15_-_99705490 0.10 ENSMUST00000163472.2
predicted gene, 17349
chr10_-_64090241 0.09 ENSMUST00000133588.1
leucine rich repeat transmembrane neuronal 3
chr2_+_119237531 0.09 ENSMUST00000110817.2
serine protease inhibitor, Kunitz type 1
chr2_+_143915273 0.09 ENSMUST00000103172.3
destrin
chr9_+_108953597 0.09 ENSMUST00000026740.5
collagen, type VII, alpha 1
chr2_+_119237351 0.09 ENSMUST00000028783.7
serine protease inhibitor, Kunitz type 1
chr17_+_53479212 0.09 ENSMUST00000017975.5
RAB5A, member RAS oncogene family
chr6_+_4755327 0.09 ENSMUST00000176551.1
paternally expressed 10
chr3_+_121723515 0.09 ENSMUST00000029771.8
coagulation factor III
chr2_+_164948219 0.09 ENSMUST00000017881.2
matrix metallopeptidase 9
chr2_+_119237453 0.09 ENSMUST00000110816.1
serine protease inhibitor, Kunitz type 1
chr7_+_110772604 0.09 ENSMUST00000005829.6
adenosine monophosphate deaminase 3
chr11_-_60036917 0.09 ENSMUST00000102692.3
phosphatidylethanolamine N-methyltransferase
chr1_+_107589997 0.09 ENSMUST00000112706.2
ENSMUST00000000514.4
serine (or cysteine) peptidase inhibitor, clade B, member 8
chr19_+_36409719 0.09 ENSMUST00000062389.5
polycomb group ring finger 5
chr19_+_5050807 0.08 ENSMUST00000025818.6
Ras and Rab interactor 1
chr4_+_109406623 0.08 ENSMUST00000124209.1
tetratricopeptide repeat domain 39A
chr10_+_80264942 0.08 ENSMUST00000105362.1
ENSMUST00000105361.3
DAZ associated protein 1
chr19_-_36736653 0.08 ENSMUST00000087321.2
protein phosphatase 1, regulatory (inhibitor) subunit 3C
chr13_-_62858364 0.08 ENSMUST00000021907.7
fructose bisphosphatase 2
chr1_+_171437535 0.08 ENSMUST00000043839.4
F11 receptor
chr11_-_109473598 0.08 ENSMUST00000070152.5
solute carrier family 16 (monocarboxylic acid transporters), member 6
chr17_+_43953191 0.08 ENSMUST00000044792.4
regulator of calcineurin 2
chr7_+_141338880 0.08 ENSMUST00000026577.6
EPS8-like 2
chr19_+_29251748 0.08 ENSMUST00000065796.3
ENSMUST00000025705.6
Janus kinase 2
chr11_+_116533257 0.08 ENSMUST00000154034.1
sphingosine kinase 1
chr11_+_94328242 0.08 ENSMUST00000021227.5
ankyrin repeat domain 40
chr2_+_69380431 0.08 ENSMUST00000063690.3
dehydrogenase/reductase (SDR family) member 9
chr6_-_99044414 0.07 ENSMUST00000177507.1
ENSMUST00000123992.1
forkhead box P1
chr12_+_108334341 0.07 ENSMUST00000021684.4
cytochrome P450, family 46, subfamily a, polypeptide 1

Network of associatons between targets according to the STRING database.

First level regulatory network of Fos

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.2 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.2 0.7 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.1 0.9 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.1 0.5 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 0.7 GO:0002159 desmosome assembly(GO:0002159)
0.1 0.2 GO:0071613 granzyme B production(GO:0071613) regulation of granzyme B production(GO:0071661) positive regulation of granzyme B production(GO:0071663)
0.1 0.6 GO:1902847 regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.1 0.5 GO:1905169 protein localization to phagocytic vesicle(GO:1905161) regulation of protein localization to phagocytic vesicle(GO:1905169) positive regulation of protein localization to phagocytic vesicle(GO:1905171)
0.1 0.5 GO:0036135 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.1 0.5 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.1 0.3 GO:0002343 peripheral B cell selection(GO:0002343) B cell affinity maturation(GO:0002344)
0.1 0.4 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.1 0.4 GO:0002780 antimicrobial peptide biosynthetic process(GO:0002777) antibacterial peptide biosynthetic process(GO:0002780)
0.1 0.2 GO:0060720 spongiotrophoblast cell proliferation(GO:0060720) cell proliferation involved in embryonic placenta development(GO:0060722)
0.1 0.8 GO:0002756 MyD88-independent toll-like receptor signaling pathway(GO:0002756)
0.1 0.3 GO:1903575 cornified envelope assembly(GO:1903575)
0.1 0.5 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1 0.2 GO:0034148 regulation of granuloma formation(GO:0002631) negative regulation of granuloma formation(GO:0002632) regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070425) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070433) tolerance induction to lipopolysaccharide(GO:0072573)
0.1 0.2 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.1 0.3 GO:1990839 response to endothelin(GO:1990839)
0.1 0.2 GO:0009816 defense response to bacterium, incompatible interaction(GO:0009816) regulation of defense response to bacterium, incompatible interaction(GO:1902477)
0.1 0.4 GO:0001866 NK T cell proliferation(GO:0001866)
0.1 0.3 GO:0002461 complement receptor mediated signaling pathway(GO:0002430) tolerance induction dependent upon immune response(GO:0002461)
0.0 0.4 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.0 0.3 GO:0052205 modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.0 0.1 GO:0015766 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.0 0.4 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.0 0.1 GO:2000642 negative regulation of early endosome to late endosome transport(GO:2000642)
0.0 0.2 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.0 0.1 GO:0002268 follicular dendritic cell activation(GO:0002266) follicular dendritic cell differentiation(GO:0002268)
0.0 0.3 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.2 GO:2001183 negative regulation of interleukin-12 secretion(GO:2001183)
0.0 0.1 GO:0046351 disaccharide biosynthetic process(GO:0046351)
0.0 0.2 GO:0021776 optic nerve morphogenesis(GO:0021631) smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
0.0 0.1 GO:0071873 response to norepinephrine(GO:0071873)
0.0 0.5 GO:0071361 cellular response to ethanol(GO:0071361)
0.0 0.1 GO:2000872 positive regulation of progesterone secretion(GO:2000872)
0.0 0.2 GO:0070384 Harderian gland development(GO:0070384)
0.0 0.2 GO:0032329 serine transport(GO:0032329)
0.0 0.1 GO:0045645 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.0 0.1 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.0 0.2 GO:0046133 pyrimidine ribonucleoside catabolic process(GO:0046133)
0.0 0.2 GO:0015820 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.0 0.2 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0 0.1 GO:0036414 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.0 0.2 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 0.4 GO:0051798 positive regulation of hair follicle development(GO:0051798)
0.0 0.1 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.0 0.9 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.0 0.1 GO:0031959 mineralocorticoid receptor signaling pathway(GO:0031959) positive regulation of growth hormone receptor signaling pathway(GO:0060399) response to interleukin-12(GO:0070671)
0.0 0.1 GO:0031509 telomeric heterochromatin assembly(GO:0031509) negative regulation of chromosome condensation(GO:1902340)
0.0 0.3 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.1 GO:0046813 receptor-mediated virion attachment to host cell(GO:0046813)
0.0 0.1 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.0 0.1 GO:0030043 actin filament fragmentation(GO:0030043)
0.0 0.2 GO:0035092 sperm chromatin condensation(GO:0035092)
0.0 0.1 GO:0090579 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.0 0.3 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.0 0.1 GO:1901909 diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.0 0.1 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.0 0.2 GO:0072602 interleukin-4 secretion(GO:0072602)
0.0 0.2 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.2 GO:0009181 purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
0.0 0.1 GO:0014826 regulation of systemic arterial blood pressure by endothelin(GO:0003100) vein smooth muscle contraction(GO:0014826)
0.0 0.3 GO:0070831 basement membrane assembly(GO:0070831)
0.0 0.2 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.0 GO:0034140 negative regulation of toll-like receptor 3 signaling pathway(GO:0034140)
0.0 0.3 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0 0.2 GO:0016540 protein autoprocessing(GO:0016540)
0.0 0.1 GO:0036233 glycine import(GO:0036233)
0.0 0.2 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.0 0.2 GO:0070842 aggresome assembly(GO:0070842)
0.0 0.1 GO:0098909 regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.0 0.1 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)
0.0 0.1 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.0 0.0 GO:1900477 negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter(GO:1900477)
0.0 0.1 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.0 0.2 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.0 0.0 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792) negative regulation of determination of dorsal identity(GO:2000016)
0.0 0.3 GO:0032060 bleb assembly(GO:0032060)
0.0 0.5 GO:0010107 potassium ion import(GO:0010107)
0.0 0.1 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.0 0.1 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.5 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.1 GO:2000680 regulation of rubidium ion transport(GO:2000680)
0.0 0.1 GO:0032261 purine nucleotide salvage(GO:0032261) IMP salvage(GO:0032264)
0.0 0.1 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.2 GO:0006968 cellular defense response(GO:0006968)
0.0 0.1 GO:0046085 adenosine metabolic process(GO:0046085)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0005914 spot adherens junction(GO:0005914)
0.1 0.4 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 0.3 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.1 0.3 GO:0005610 laminin-5 complex(GO:0005610)
0.1 0.5 GO:0045098 type III intermediate filament(GO:0045098)
0.0 0.6 GO:0097418 neurofibrillary tangle(GO:0097418)
0.0 0.2 GO:1990590 ATF1-ATF4 transcription factor complex(GO:1990590)
0.0 0.1 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.0 0.1 GO:0098842 postsynaptic early endosome(GO:0098842)
0.0 0.5 GO:0098644 complex of collagen trimers(GO:0098644)
0.0 0.1 GO:1990761 growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
0.0 0.3 GO:0005922 connexon complex(GO:0005922)
0.0 0.4 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.1 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.0 0.2 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.0 GO:0036488 CHOP-C/EBP complex(GO:0036488)
0.0 0.5 GO:0005771 multivesicular body(GO:0005771)
0.0 0.4 GO:0045095 keratin filament(GO:0045095)
0.0 0.1 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.1 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.0 0.1 GO:0005915 zonula adherens(GO:0005915)
0.0 0.2 GO:0042627 chylomicron(GO:0042627)
0.0 0.3 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.1 GO:0090533 cation-transporting ATPase complex(GO:0090533)
0.0 0.5 GO:0015030 Cajal body(GO:0015030)
0.0 0.1 GO:0072687 meiotic spindle(GO:0072687)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0045353 interleukin-1, Type II receptor binding(GO:0005151) interleukin-1 receptor antagonist activity(GO:0005152) interleukin-1 Type I receptor antagonist activity(GO:0045352) interleukin-1 Type II receptor antagonist activity(GO:0045353)
0.2 0.8 GO:1990254 keratin filament binding(GO:1990254)
0.1 0.5 GO:0008859 exoribonuclease II activity(GO:0008859)
0.1 0.8 GO:0045545 syndecan binding(GO:0045545)
0.1 0.3 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.1 0.3 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.1 0.3 GO:0048408 epidermal growth factor binding(GO:0048408)
0.1 0.4 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.2 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.4 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 0.1 GO:0015157 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.0 0.7 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.3 GO:0004875 complement receptor activity(GO:0004875)
0.0 0.3 GO:0008481 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.0 0.2 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0 0.1 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 0.2 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.2 GO:0004850 uridine phosphorylase activity(GO:0004850)
0.0 0.5 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.1 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.1 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.2 GO:0048039 ubiquinone binding(GO:0048039)
0.0 0.6 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.1 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.0 0.2 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.1 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.1 GO:0008486 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.0 0.1 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.5 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.2 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 0.7 GO:0008009 chemokine activity(GO:0008009)
0.0 0.1 GO:0051425 PTB domain binding(GO:0051425)
0.0 0.5 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.1 GO:0004947 bradykinin receptor activity(GO:0004947)
0.0 0.5 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.1 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.0 0.1 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0 0.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.1 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.2 GO:0043262 adenosine-diphosphatase activity(GO:0043262)
0.0 0.5 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.2 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 1.1 GO:0005518 collagen binding(GO:0005518)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.3 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.1 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.3 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.2 GO:0042288 MHC class I protein binding(GO:0042288)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 ST STAT3 PATHWAY STAT3 Pathway
0.0 0.3 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.6 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.5 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.6 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.2 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.3 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.2 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.5 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.5 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.5 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.5 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.3 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 0.7 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.5 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.5 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.2 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.4 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 1.0 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.5 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.1 REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.0 0.6 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.6 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 1.2 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.0 0.2 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.2 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.2 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.1 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism