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12D miR HR13_24

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Results for Pou5f1

Z-value: 1.19

Motif logo

Transcription factors associated with Pou5f1

Gene Symbol Gene ID Gene Info
ENSMUSG00000024406.10 POU domain, class 5, transcription factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Pou5f1mm10_v2_chr17_+_35506018_35506049-0.412.1e-01Click!

Activity profile of Pou5f1 motif

Sorted Z-values of Pou5f1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr8_+_54954728 2.93 ENSMUST00000033915.7
glycoprotein m6a
chr11_+_110399115 2.60 ENSMUST00000020949.5
ENSMUST00000100260.1
mitogen-activated protein kinase kinase 6
chr5_+_21372642 2.58 ENSMUST00000035799.5
fibrinogen-like protein 2
chr13_+_89540636 2.36 ENSMUST00000022108.7
hyaluronan and proteoglycan link protein 1
chr10_+_115817247 2.17 ENSMUST00000035563.7
ENSMUST00000080630.3
ENSMUST00000179196.1
tetraspanin 8
chr9_+_53301571 2.17 ENSMUST00000051014.1
exophilin 5
chrX_+_103321398 2.04 ENSMUST00000033689.2
caudal type homeobox 4
chr3_+_60081861 2.01 ENSMUST00000029326.5
succinate receptor 1
chr12_-_86988676 1.91 ENSMUST00000095521.2
zinc finger, DHHC-type containing 22
chr3_-_144819494 1.80 ENSMUST00000029929.7
chloride channel calcium activated 2
chr4_-_11386757 1.74 ENSMUST00000108313.1
ENSMUST00000108311.2
epithelial splicing regulatory protein 1
chr11_-_119086221 1.73 ENSMUST00000026665.7
chromobox 4
chr2_-_103303179 1.70 ENSMUST00000090475.3
ets homologous factor
chr8_+_76902277 1.70 ENSMUST00000109912.1
ENSMUST00000128862.1
ENSMUST00000109911.1
nuclear receptor subfamily 3, group C, member 2
chr2_-_103303158 1.65 ENSMUST00000111176.2
ets homologous factor
chr4_-_11386679 1.59 ENSMUST00000043781.7
ENSMUST00000108310.1
epithelial splicing regulatory protein 1
chr11_-_3504766 1.59 ENSMUST00000044507.5
inositol polyphosphate 5-phosphatase J
chr2_-_25196759 1.53 ENSMUST00000081869.6
torsin family 4, member A
chr4_-_133263042 1.48 ENSMUST00000105908.3
ENSMUST00000030674.7
synaptotagmin-like 1
chr17_-_91092715 1.47 ENSMUST00000160800.2
ENSMUST00000159778.1
ENSMUST00000160844.3
neurexin I
chr16_+_23224724 1.41 ENSMUST00000023601.7
beta galactoside alpha 2,6 sialyltransferase 1
chr8_-_122678653 1.41 ENSMUST00000134045.1
core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human)
chr5_+_66968416 1.37 ENSMUST00000038188.7
LIM and calponin homology domains 1
chr15_+_57694651 1.33 ENSMUST00000096430.4
zinc fingers and homeoboxes 2
chr15_+_85017138 1.30 ENSMUST00000023070.5
uroplakin 3A
chr9_+_59578192 1.28 ENSMUST00000118549.1
ENSMUST00000034840.3
CUGBP, Elav-like family member 6
chr8_+_68880491 1.28 ENSMUST00000015712.8
lipoprotein lipase
chr3_-_97297778 1.23 ENSMUST00000181368.1
predicted gene, 17608
chr6_-_30693676 1.19 ENSMUST00000169422.1
ENSMUST00000115131.1
ENSMUST00000115130.2
ENSMUST00000031810.8
centrosomal protein 41
chr15_-_100599983 1.14 ENSMUST00000073837.6
POU domain, class 6, transcription factor 1
chr6_-_138421379 1.12 ENSMUST00000163065.1
LIM domain only 3
chrX_-_103483205 1.11 ENSMUST00000127786.2
inactive X specific transcripts
chr11_-_96747419 1.10 ENSMUST00000181758.1
RIKEN cDNA 2010300F17 gene
chr4_-_137118135 1.08 ENSMUST00000154285.1
predicted gene 13001
chr4_-_62434722 1.08 ENSMUST00000107454.1
ring finger protein 183
chr5_-_123865491 1.08 ENSMUST00000057145.5
niacin receptor 1
chr17_-_27133902 1.06 ENSMUST00000119227.1
ENSMUST00000025045.8
ubiquinol-cytochrome c reductase complex assembly factor 2
chr13_+_42680565 1.06 ENSMUST00000128646.1
phosphatase and actin regulator 1
chr14_+_66868850 1.05 ENSMUST00000100453.1
predicted gene 5464
chr5_+_66968559 1.03 ENSMUST00000127184.1
LIM and calponin homology domains 1
chr7_-_30856178 1.02 ENSMUST00000094583.1
free fatty acid receptor 3
chr9_+_104569754 0.98 ENSMUST00000077190.6
copine IV
chr6_-_142278836 0.97 ENSMUST00000111825.3
solute carrier organic anion transporter family, member 1a5
chr1_-_144004142 0.97 ENSMUST00000127206.1
regulator of G-protein signaling 2
chr2_+_103566304 0.92 ENSMUST00000076212.3
ankyrin repeat and BTB (POZ) domain containing 2
chr9_+_104569671 0.92 ENSMUST00000057742.8
copine IV
chr17_-_28486082 0.88 ENSMUST00000079413.3
FK506 binding protein 5
chr2_+_155381808 0.88 ENSMUST00000043237.7
ENSMUST00000174685.1
transformation related protein 53 inducible nuclear protein 2
chr13_+_40886758 0.87 ENSMUST00000069958.7
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme
chr19_+_55741810 0.87 ENSMUST00000111657.3
ENSMUST00000061496.9
ENSMUST00000041717.7
ENSMUST00000111662.4
transcription factor 7 like 2, T cell specific, HMG box
chr13_-_23683941 0.87 ENSMUST00000171127.1
histone cluster 1, H2ac
chr16_-_22439570 0.86 ENSMUST00000170393.1
ets variant gene 5
chr10_-_64090265 0.85 ENSMUST00000105439.1
leucine rich repeat transmembrane neuronal 3
chr18_+_50051702 0.85 ENSMUST00000134348.1
ENSMUST00000153873.2
tumor necrosis factor, alpha-induced protein 8
chr11_-_96747405 0.85 ENSMUST00000180492.1
RIKEN cDNA 2010300F17 gene
chr17_+_28207778 0.84 ENSMUST00000002327.5
differentially expressed in FDCP 6
chr4_-_128806045 0.84 ENSMUST00000106072.2
ENSMUST00000170934.1
zinc finger protein 362
chr3_-_96220880 0.83 ENSMUST00000090782.3
histone cluster 2, H2ac
chr2_+_155382186 0.83 ENSMUST00000134218.1
transformation related protein 53 inducible nuclear protein 2
chr17_+_27057288 0.82 ENSMUST00000049308.8
inositol 1,4,5-triphosphate receptor 3
chr4_+_102254993 0.82 ENSMUST00000106908.2
phosphodiesterase 4B, cAMP specific
chr3_+_96219858 0.82 ENSMUST00000073115.4
histone cluster 2, H2ab
chr7_-_29168647 0.82 ENSMUST00000048923.6
sprouty-related, EVH1 domain containing 3
chr7_+_81213567 0.80 ENSMUST00000026672.7
phosphodiesterase 8A
chr15_-_95830072 0.79 ENSMUST00000168960.1
predicted gene, 17546
chr13_+_40917626 0.79 ENSMUST00000067778.6
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme
chr19_+_56287911 0.78 ENSMUST00000095948.4
hyaluronic acid binding protein 2
chr3_+_96221111 0.78 ENSMUST00000090781.6
histone cluster 2, H2be
chr13_-_23934156 0.77 ENSMUST00000052776.2
histone cluster 1, H2ba
chr1_+_74391479 0.75 ENSMUST00000027367.7
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
chr6_-_13839916 0.74 ENSMUST00000060442.7
G protein-coupled receptor 85
chr5_-_101665195 0.74 ENSMUST00000044125.8
NK6 homeobox 1
chr2_-_26092149 0.72 ENSMUST00000114159.2
nucleus accumbens associated 2, BEN and BTB (POZ) domain containing
chr7_+_91090728 0.71 ENSMUST00000074273.3
discs, large homolog 2 (Drosophila)
chr1_-_135258449 0.71 ENSMUST00000003135.7
E74-like factor 3
chr3_+_83766300 0.71 ENSMUST00000029625.7
secreted frizzled-related protein 2
chr7_+_91090697 0.70 ENSMUST00000107196.2
discs, large homolog 2 (Drosophila)
chr16_-_92697315 0.70 ENSMUST00000168195.1
ENSMUST00000113956.3
runt related transcription factor 1
chr1_-_168431896 0.69 ENSMUST00000176540.1
pre B cell leukemia homeobox 1
chr10_+_39612934 0.69 ENSMUST00000019987.6
TRAF3 interacting protein 2
chr3_+_31902507 0.69 ENSMUST00000119310.1
potassium large conductance calcium-activated channel, subfamily M, beta member 2
chr1_-_126830632 0.68 ENSMUST00000112583.1
ENSMUST00000094609.3
NCK-associated protein 5
chr8_-_87959560 0.68 ENSMUST00000109655.2
zinc finger protein 423
chr7_+_122289297 0.68 ENSMUST00000064989.5
ENSMUST00000064921.4
protein kinase C, beta
chr13_+_23684192 0.67 ENSMUST00000018246.4
histone cluster 1, H2bc
chr7_-_44997221 0.67 ENSMUST00000152341.1
BCL2-like 12 (proline rich)
chr1_+_87470258 0.66 ENSMUST00000027476.4
RIKEN cDNA 3110079O15 gene
chr6_+_88724667 0.66 ENSMUST00000163271.1
monoglyceride lipase
chr11_-_23770953 0.66 ENSMUST00000102864.3
reticuloendotheliosis oncogene
chr10_-_53638269 0.66 ENSMUST00000164393.1
family with sequence similarity 184, member A
chr7_-_120982260 0.65 ENSMUST00000033169.8
cerebellar degeneration-related 2
chr9_-_95815389 0.64 ENSMUST00000119760.1
plastin 1 (I-isoform)
chr6_+_110645572 0.64 ENSMUST00000071076.6
ENSMUST00000172951.1
glutamate receptor, metabotropic 7
chr12_-_40199315 0.64 ENSMUST00000095760.2
leucine-rich single-pass membrane protein 1
chr2_+_30595037 0.63 ENSMUST00000102853.3
CSA-conditional, T cell activation-dependent protein
chr7_-_90129339 0.63 ENSMUST00000181189.1
RIKEN cDNA 2310010J17 gene
chr6_-_69400097 0.63 ENSMUST00000177795.1
immunoglobulin kappa variable 4-62
chr4_-_129696579 0.63 ENSMUST00000137640.1
transmembrane protein 39b
chr10_+_97479470 0.63 ENSMUST00000105287.3
decorin
chr4_-_129623870 0.63 ENSMUST00000106035.1
ENSMUST00000150357.1
ENSMUST00000030586.8
coiled coil domain containing 28B
chr16_-_23225334 0.62 ENSMUST00000055369.4
cDNA sequence BC106179
chr3_+_125404292 0.62 ENSMUST00000144344.1
N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
chr12_+_52516077 0.62 ENSMUST00000110725.1
Rho GTPase activating protein 5
chr13_+_23574381 0.62 ENSMUST00000090776.4
histone cluster 1, H2ad
chr13_+_22035821 0.61 ENSMUST00000110455.2
histone cluster 1, H2bk
chr1_-_168431502 0.60 ENSMUST00000064438.4
pre B cell leukemia homeobox 1
chr2_-_170194033 0.60 ENSMUST00000180625.1
predicted gene, 17619
chr17_-_90455872 0.60 ENSMUST00000174337.1
ENSMUST00000172466.1
neurexin I
chr17_+_47140942 0.58 ENSMUST00000077951.7
transcriptional regulating factor 1
chr13_+_23746734 0.57 ENSMUST00000099703.2
histone cluster 1, H2bb
chr3_+_31902666 0.57 ENSMUST00000119970.1
ENSMUST00000178668.1
potassium large conductance calcium-activated channel, subfamily M, beta member 2
chr13_-_18172540 0.57 ENSMUST00000184299.1
ENSMUST00000063256.5
POU domain, class 6, transcription factor 2
chr14_+_70890099 0.57 ENSMUST00000022699.8
glial cell line derived neurotrophic factor family receptor alpha 2
chr3_-_84220853 0.57 ENSMUST00000154152.1
ENSMUST00000107693.2
ENSMUST00000107695.2
tripartite motif-containing 2
chr11_+_103103051 0.57 ENSMUST00000152971.1
acyl-Coenzyme A binding domain containing 4
chr6_-_52240841 0.56 ENSMUST00000121043.1
homeobox A10
chr19_-_40994133 0.56 ENSMUST00000117695.1
B cell linker
chr5_+_66968961 0.56 ENSMUST00000132991.1
LIM and calponin homology domains 1
chr1_+_34579693 0.55 ENSMUST00000052670.8
APC membrane recruitment 3
chr6_+_88724828 0.55 ENSMUST00000089449.2
monoglyceride lipase
chr11_+_69838514 0.54 ENSMUST00000133967.1
ENSMUST00000094065.4
transmembrane protein 256
chr2_+_52038005 0.54 ENSMUST00000065927.5
tumor necrosis factor alpha induced protein 6
chr6_-_52226165 0.54 ENSMUST00000114425.2
homeobox A9
chr2_+_69135799 0.54 ENSMUST00000041865.7
nitric oxide synthase trafficker
chr13_-_23574196 0.53 ENSMUST00000105106.1
histone cluster 1, H2bf
chr6_-_65144908 0.53 ENSMUST00000031982.4
hematopoietic prostaglandin D synthase
chr11_-_116077954 0.52 ENSMUST00000106451.1
ENSMUST00000075036.2
unc-13 homolog D (C. elegans)
chr1_+_177444653 0.52 ENSMUST00000094276.3
zinc finger and BTB domain containing 18
chrX_-_167209149 0.52 ENSMUST00000112176.1
thymosin, beta 4, X chromosome
chr7_+_107370728 0.52 ENSMUST00000137663.1
ENSMUST00000073459.5
synaptotagmin IX
chr19_+_53460610 0.51 ENSMUST00000180442.1
RIKEN cDNA 4833407H14 gene
chr2_+_109917639 0.51 ENSMUST00000046548.7
ENSMUST00000111037.2
leucine-rich repeat-containing G protein-coupled receptor 4
chr11_-_116077606 0.51 ENSMUST00000106450.1
unc-13 homolog D (C. elegans)
chr12_-_36042476 0.50 ENSMUST00000020896.8
tetraspanin 13
chr18_+_37484955 0.49 ENSMUST00000053856.4
protocadherin beta 17
chr17_-_24533709 0.49 ENSMUST00000061764.7
RAB26, member RAS oncogene family
chr4_-_35845204 0.49 ENSMUST00000164772.1
ENSMUST00000065173.2
leucine rich repeat and Ig domain containing 2
chr19_+_56287943 0.48 ENSMUST00000166049.1
hyaluronic acid binding protein 2
chr5_-_122989086 0.48 ENSMUST00000046073.9
lysine (K)-specific demethylase 2B
chr7_-_109731708 0.48 ENSMUST00000035372.1
achaete-scute complex homolog 3 (Drosophila)
chr13_-_41358990 0.48 ENSMUST00000163623.1
neural precursor cell expressed, developmentally down-regulated gene 9
chr14_+_79515618 0.48 ENSMUST00000110835.1
E74-like factor 1
chr8_+_22808275 0.47 ENSMUST00000068068.4
RIKEN cDNA 1700041G16 gene
chr6_-_56901870 0.47 ENSMUST00000101367.2
5'-nucleotidase, cytosolic III
chr5_+_13399309 0.46 ENSMUST00000030714.7
ENSMUST00000141968.1
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr13_+_37826225 0.46 ENSMUST00000128570.1
ras responsive element binding protein 1
chr13_-_22035589 0.45 ENSMUST00000091742.4
histone cluster 1, H2ah
chr10_+_118860826 0.45 ENSMUST00000059966.4
RIKEN cDNA 4932442E05 gene
chr2_+_143546144 0.45 ENSMUST00000028905.9
proprotein convertase subtilisin/kexin type 2
chr1_+_143640664 0.44 ENSMUST00000038252.2
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
chr14_-_88471396 0.44 ENSMUST00000061628.5
protocadherin 20
chr9_+_89199319 0.44 ENSMUST00000138109.1
5, 10-methenyltetrahydrofolate synthetase
chr9_+_78175898 0.44 ENSMUST00000180974.1
RIKEN cDNA C920006O11 gene
chr3_+_76074270 0.44 ENSMUST00000038364.8
follistatin-like 5
chrX_-_164250368 0.43 ENSMUST00000112263.1
BMX non-receptor tyrosine kinase
chr7_+_5015466 0.43 ENSMUST00000086349.3
zinc finger protein 524
chr4_+_43562672 0.42 ENSMUST00000167751.1
ENSMUST00000132631.1
cAMP responsive element binding protein 3
chr8_+_47822143 0.41 ENSMUST00000079639.2
claudin 24
chr4_-_129696817 0.41 ENSMUST00000102588.3
transmembrane protein 39b
chr5_-_31291026 0.41 ENSMUST00000041565.7
intraflagellar transport 172
chr19_+_20601958 0.41 ENSMUST00000087638.3
aldehyde dehydrogenase family 1, subfamily A1
chr11_-_100527896 0.41 ENSMUST00000107389.1
ENSMUST00000007131.9
ATP citrate lyase
chr13_-_22042949 0.41 ENSMUST00000091741.4
histone cluster 1, H2ag
chr2_+_28192971 0.41 ENSMUST00000113920.1
olfactomedin 1
chr13_-_12520377 0.40 ENSMUST00000179308.1
EDAR (ectodysplasin-A receptor)-associated death domain
chr13_+_113209659 0.40 ENSMUST00000038144.8
endothelial cell-specific molecule 1
chr5_+_146231211 0.40 ENSMUST00000161181.1
ENSMUST00000161652.1
ENSMUST00000031640.8
ENSMUST00000159467.1
cyclin-dependent kinase 8
chr5_+_123015010 0.39 ENSMUST00000121652.1
ENSMUST00000051016.4
ORAI calcium release-activated calcium modulator 1
chr19_+_16435616 0.39 ENSMUST00000025602.2
guanine nucleotide binding protein, alpha 14
chr13_-_23571151 0.39 ENSMUST00000102969.3
histone cluster 1, H2ae
chr13_+_21722057 0.38 ENSMUST00000110476.3
histone cluster 1, H2bm
chr1_-_66817536 0.37 ENSMUST00000068168.3
ENSMUST00000113987.1
KAT8 regulatory NSL complex subunit 1-like
chr15_-_53346118 0.37 ENSMUST00000077273.2
exostoses (multiple) 1
chr2_-_26503814 0.35 ENSMUST00000028288.4
notch 1
chr14_-_12345847 0.35 ENSMUST00000022262.4
Fez family zinc finger 2
chr10_+_128706251 0.35 ENSMUST00000054125.8
premelanosome protein
chr7_+_44997648 0.34 ENSMUST00000003284.8
ENSMUST00000107835.1
interferon regulatory factor 3
chr12_+_89812467 0.34 ENSMUST00000110133.2
ENSMUST00000110130.2
neurexin III
chr12_+_52699297 0.34 ENSMUST00000095737.3
A kinase (PRKA) anchor protein 6
chr3_+_92352141 0.34 ENSMUST00000068399.1
small proline-rich protein 2E
chr1_-_126830786 0.34 ENSMUST00000162646.1
NCK-associated protein 5
chr3_+_125404072 0.34 ENSMUST00000173932.1
N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
chr4_+_128883549 0.34 ENSMUST00000035667.8
tripartite motif-containing 62
chr2_-_70825726 0.34 ENSMUST00000038584.8
tousled-like kinase 1
chr13_+_97241096 0.34 ENSMUST00000041623.7
ectodermal-neural cortex 1
chrX_-_112698642 0.33 ENSMUST00000039887.3
premature ovarian failure 1B
chr4_+_97772734 0.33 ENSMUST00000152023.1
nuclear factor I/A
chr1_-_91459254 0.33 ENSMUST00000069620.8
period circadian clock 2
chr13_+_22043189 0.32 ENSMUST00000110452.1
histone cluster 1, H2bj
chr9_-_104102550 0.32 ENSMUST00000050139.4
atypical chemokine receptor 4
chr11_+_88294043 0.32 ENSMUST00000037268.4
RIKEN cDNA 1700106J16 gene
chr3_-_102782708 0.32 ENSMUST00000029450.3
ENSMUST00000172026.1
ENSMUST00000170856.1
thyroid stimulating hormone, beta subunit
chr1_-_168431695 0.32 ENSMUST00000176790.1
pre B cell leukemia homeobox 1
chr18_-_74961252 0.32 ENSMUST00000066532.4
lipase, endothelial
chr2_-_38926217 0.32 ENSMUST00000076275.4
ENSMUST00000142130.1
nuclear receptor subfamily 6, group A, member 1
chr11_-_69605829 0.30 ENSMUST00000047889.6
ATPase, Na+/K+ transporting, beta 2 polypeptide
chr2_-_36105271 0.30 ENSMUST00000112960.1
ENSMUST00000112967.5
ENSMUST00000112963.1
LIM homeobox protein 6
chr17_+_29490812 0.30 ENSMUST00000024811.6
proviral integration site 1
chr6_+_29694204 0.29 ENSMUST00000046750.7
ENSMUST00000115250.3
tetraspanin 33
chr9_+_86743641 0.29 ENSMUST00000179574.1
protease, serine, 35

Network of associatons between targets according to the STRING database.

First level regulatory network of Pou5f1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0031959 mineralocorticoid receptor signaling pathway(GO:0031959)
0.5 2.1 GO:0090126 protein complex assembly involved in synapse maturation(GO:0090126)
0.4 2.2 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.4 1.4 GO:1990743 protein sialylation(GO:1990743)
0.3 1.0 GO:0002879 positive regulation of acute inflammatory response to non-antigenic stimulus(GO:0002879)
0.3 1.7 GO:0036438 maintenance of lens transparency(GO:0036438)
0.2 0.7 GO:1900477 negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter(GO:1900477)
0.2 0.7 GO:2000041 dermatome development(GO:0061054) regulation of dermatome development(GO:0061183) regulation of midbrain dopaminergic neuron differentiation(GO:1904956) regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
0.2 0.7 GO:2000872 positive regulation of progesterone secretion(GO:2000872)
0.2 2.6 GO:0032308 positive regulation of prostaglandin secretion(GO:0032308)
0.2 1.3 GO:0015840 urea transport(GO:0015840)
0.2 1.4 GO:0002432 granuloma formation(GO:0002432)
0.2 1.2 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.2 2.8 GO:0002227 innate immune response in mucosa(GO:0002227)
0.2 0.8 GO:0055095 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096)
0.2 1.0 GO:0010519 negative regulation of phospholipase activity(GO:0010519)
0.2 0.6 GO:1902896 terminal web assembly(GO:1902896)
0.2 1.1 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.2 0.8 GO:0021993 initiation of neural tube closure(GO:0021993)
0.1 0.9 GO:0042078 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.1 0.4 GO:0019046 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990) establishment of viral latency(GO:0019043) release from viral latency(GO:0019046)
0.1 1.4 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.1 0.7 GO:0097491 trigeminal nerve morphogenesis(GO:0021636) trigeminal nerve structural organization(GO:0021637) trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) sympathetic neuron projection extension(GO:0097490) sympathetic neuron projection guidance(GO:0097491) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.1 0.8 GO:0050917 sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
0.1 0.7 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.1 0.6 GO:0001661 conditioned taste aversion(GO:0001661)
0.1 1.3 GO:0005513 detection of calcium ion(GO:0005513)
0.1 0.5 GO:0030070 insulin processing(GO:0030070)
0.1 0.3 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.1 0.3 GO:0031554 regulation of DNA-templated transcription, termination(GO:0031554)
0.1 0.4 GO:0045608 negative regulation of auditory receptor cell differentiation(GO:0045608)
0.1 0.7 GO:0021853 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.1 1.0 GO:0044334 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334)
0.1 0.3 GO:0090264 immune complex clearance by monocytes and macrophages(GO:0002436) astrocyte chemotaxis(GO:0035700) regulation of immune complex clearance by monocytes and macrophages(GO:0090264) positive regulation of immune complex clearance by monocytes and macrophages(GO:0090265) negative regulation of eosinophil activation(GO:1902567) positive regulation of CD8-positive, alpha-beta T cell extravasation(GO:2000451) regulation of astrocyte chemotaxis(GO:2000458)
0.1 0.2 GO:0034136 negative regulation of toll-like receptor 2 signaling pathway(GO:0034136)
0.1 0.5 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.1 0.7 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.1 0.5 GO:1901894 regulation of calcium-transporting ATPase activity(GO:1901894)
0.1 0.5 GO:0072282 metanephric nephron tubule morphogenesis(GO:0072282) epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.1 0.4 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.1 0.4 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.1 1.1 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.1 0.8 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.1 1.4 GO:0045161 neuronal ion channel clustering(GO:0045161)
0.1 0.6 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.1 0.6 GO:1902548 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747) negative regulation of cellular response to vascular endothelial growth factor stimulus(GO:1902548)
0.1 3.5 GO:0060445 branching involved in salivary gland morphogenesis(GO:0060445)
0.1 0.3 GO:0045358 negative regulation of interferon-beta biosynthetic process(GO:0045358)
0.1 0.4 GO:0061525 hindgut development(GO:0061525)
0.1 0.7 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.1 0.4 GO:0023041 neuronal signal transduction(GO:0023041)
0.1 0.7 GO:1902166 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902166)
0.1 0.3 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982) positive regulation of lipoprotein particle clearance(GO:0010986)
0.1 0.4 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.1 0.2 GO:0021830 interneuron migration from the subpallium to the cortex(GO:0021830)
0.1 0.3 GO:1903288 positive regulation of potassium ion import(GO:1903288)
0.1 1.1 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.1 1.6 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.1 2.8 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.1 0.1 GO:0060686 negative regulation of prostatic bud formation(GO:0060686)
0.1 0.3 GO:1903758 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.1 0.4 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.1 0.3 GO:2000481 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316) positive regulation of cAMP-dependent protein kinase activity(GO:2000481)
0.1 1.9 GO:0018345 protein palmitoylation(GO:0018345)
0.1 0.2 GO:0045872 positive regulation of rhodopsin gene expression(GO:0045872)
0.1 0.8 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 0.4 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1 0.2 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.1 0.2 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.1 0.1 GO:1901078 negative regulation of relaxation of muscle(GO:1901078)
0.1 0.2 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.1 0.2 GO:0060638 mesenchymal-epithelial cell signaling(GO:0060638)
0.1 2.3 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.1 2.0 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 1.3 GO:0071625 vocalization behavior(GO:0071625)
0.0 0.4 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.4 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.0 0.2 GO:0001830 trophectodermal cell fate commitment(GO:0001830)
0.0 0.2 GO:0061303 cornea development in camera-type eye(GO:0061303)
0.0 0.3 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.0 1.9 GO:0019835 cytolysis(GO:0019835)
0.0 0.2 GO:2000609 regulation of thyroid hormone generation(GO:2000609)
0.0 2.3 GO:0030195 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.0 0.7 GO:0060056 mammary gland involution(GO:0060056)
0.0 0.2 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.0 0.9 GO:0097237 cellular response to toxic substance(GO:0097237)
0.0 0.6 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.7 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 0.2 GO:0060023 soft palate development(GO:0060023)
0.0 0.2 GO:1901843 positive regulation of high voltage-gated calcium channel activity(GO:1901843)
0.0 0.5 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.3 GO:2000138 positive regulation of cell proliferation involved in heart morphogenesis(GO:2000138)
0.0 0.4 GO:0072189 ureter development(GO:0072189)
0.0 1.1 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.8 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.3 GO:0060573 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.0 0.3 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.0 4.6 GO:0006342 chromatin silencing(GO:0006342)
0.0 0.2 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.4 GO:0090209 negative regulation of triglyceride metabolic process(GO:0090209)
0.0 1.7 GO:0016925 protein sumoylation(GO:0016925)
0.0 0.1 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.0 0.5 GO:0031953 negative regulation of protein autophosphorylation(GO:0031953)
0.0 0.7 GO:0006085 acetyl-CoA biosynthetic process(GO:0006085)
0.0 0.1 GO:0045347 hypermethylation of CpG island(GO:0044027) negative regulation of MHC class II biosynthetic process(GO:0045347)
0.0 0.7 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.0 0.2 GO:0061589 calcium activated phosphatidylserine scrambling(GO:0061589)
0.0 0.8 GO:1903206 negative regulation of hydrogen peroxide-induced cell death(GO:1903206)
0.0 0.2 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.1 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0 0.5 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.3 GO:0032261 purine nucleotide salvage(GO:0032261) IMP salvage(GO:0032264)
0.0 0.9 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.1 GO:0021666 rhombomere formation(GO:0021594) rhombomere 3 formation(GO:0021660) rhombomere 5 morphogenesis(GO:0021664) rhombomere 5 formation(GO:0021666)
0.0 0.4 GO:0001865 NK T cell differentiation(GO:0001865)
0.0 0.2 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.0 0.2 GO:0051013 microtubule severing(GO:0051013)
0.0 0.5 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.3 GO:0045086 positive regulation of interleukin-2 biosynthetic process(GO:0045086)
0.0 0.1 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) negative regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002587)
0.0 0.1 GO:0015680 intracellular copper ion transport(GO:0015680)
0.0 0.3 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.0 0.3 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.1 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.0 0.2 GO:0051177 meiotic sister chromatid cohesion(GO:0051177)
0.0 0.3 GO:1900194 receptor guanylyl cyclase signaling pathway(GO:0007168) negative regulation of oocyte maturation(GO:1900194)
0.0 0.1 GO:0032468 cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) manganese ion homeostasis(GO:0055071)
0.0 0.2 GO:0019532 oxalate transport(GO:0019532)
0.0 0.1 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.0 1.9 GO:0060711 labyrinthine layer development(GO:0060711)
0.0 0.1 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.0 0.0 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.0 0.1 GO:0048539 bone marrow development(GO:0048539)
0.0 0.4 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.3 GO:0031424 keratinization(GO:0031424)
0.0 0.2 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 1.1 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.1 GO:1903445 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.0 1.7 GO:0000045 autophagosome assembly(GO:0000045)
0.0 0.1 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.0 0.4 GO:0007616 long-term memory(GO:0007616)
0.0 0.5 GO:0035272 exocrine system development(GO:0035272)
0.0 0.5 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 3.6 GO:0031032 actomyosin structure organization(GO:0031032)
0.0 0.3 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.0 0.1 GO:0042573 retinoic acid metabolic process(GO:0042573)
0.0 1.6 GO:0006821 chloride transport(GO:0006821)
0.0 0.8 GO:0032611 interleukin-1 beta production(GO:0032611)
0.0 1.6 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.0 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.0 0.0 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.0 0.0 GO:2000121 regulation of removal of superoxide radicals(GO:2000121)
0.0 0.1 GO:0043383 negative T cell selection(GO:0043383)
0.0 0.4 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.2 GO:0036159 inner dynein arm assembly(GO:0036159)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0002111 BRCA2-BRAF35 complex(GO:0002111)
0.1 1.4 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 1.4 GO:0000138 Golgi trans cisterna(GO:0000138)
0.1 2.1 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 1.1 GO:0000805 X chromosome(GO:0000805)
0.1 1.0 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.1 0.3 GO:0032585 multivesicular body membrane(GO:0032585)
0.1 0.6 GO:1990357 terminal web(GO:1990357)
0.1 0.2 GO:0036019 endolysosome(GO:0036019)
0.1 5.2 GO:0000786 nucleosome(GO:0000786)
0.1 0.7 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 1.4 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 1.3 GO:0042627 chylomicron(GO:0042627)
0.1 0.2 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
0.1 0.4 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1 1.3 GO:0035102 PRC1 complex(GO:0035102)
0.1 0.4 GO:0044308 axonal spine(GO:0044308)
0.1 3.3 GO:0044295 axonal growth cone(GO:0044295)
0.1 0.6 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.1 0.3 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1 1.2 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 1.5 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.3 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.9 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.3 GO:0036128 CatSper complex(GO:0036128)
0.0 0.8 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.1 GO:0033269 internode region of axon(GO:0033269)
0.0 0.1 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.3 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.5 GO:0031045 dense core granule(GO:0031045)
0.0 0.2 GO:0019815 B cell receptor complex(GO:0019815)
0.0 0.2 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.6 GO:0098644 complex of collagen trimers(GO:0098644)
0.0 0.3 GO:0001533 cornified envelope(GO:0001533)
0.0 1.1 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.4 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.1 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 1.7 GO:0005776 autophagosome(GO:0005776)
0.0 1.6 GO:0031526 brush border membrane(GO:0031526)
0.0 0.2 GO:0036156 inner dynein arm(GO:0036156)
0.0 0.3 GO:0030057 desmosome(GO:0030057)
0.0 1.2 GO:0005814 centriole(GO:0005814)
0.0 0.1 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.2 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.3 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0017082 mineralocorticoid receptor activity(GO:0017082)
0.5 1.6 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.4 1.7 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.3 1.4 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.2 0.6 GO:0070905 serine binding(GO:0070905)
0.2 0.8 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.2 0.6 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.2 0.6 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.2 0.5 GO:0019002 GMP binding(GO:0019002)
0.2 2.1 GO:0097109 neuroligin family protein binding(GO:0097109)
0.1 0.4 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.1 1.0 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 0.8 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.4 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
0.1 0.5 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.1 2.9 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 2.6 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.1 0.4 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.1 1.0 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.1 0.7 GO:0035184 histone threonine kinase activity(GO:0035184)
0.1 0.4 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.1 1.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 0.7 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.1 0.3 GO:0035717 chemokine (C-C motif) ligand 7 binding(GO:0035717)
0.1 1.5 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 2.0 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.1 0.3 GO:0016901 glycerol-3-phosphate dehydrogenase activity(GO:0004368) oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.1 1.6 GO:0004806 triglyceride lipase activity(GO:0004806)
0.1 0.7 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 1.4 GO:0004385 guanylate kinase activity(GO:0004385)
0.1 0.7 GO:0008420 CTD phosphatase activity(GO:0008420)
0.1 0.2 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.1 0.2 GO:0005502 11-cis retinal binding(GO:0005502)
0.1 0.2 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.1 0.4 GO:1904315 transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.1 1.9 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 0.2 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.1 0.9 GO:0045499 chemorepellent activity(GO:0045499)
0.1 1.7 GO:0019789 SUMO transferase activity(GO:0019789)
0.1 0.3 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.1 0.1 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529)
0.1 0.3 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 1.1 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.2 GO:0045322 unmethylated CpG binding(GO:0045322)
0.0 1.6 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.2 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
0.0 0.9 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.6 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.2 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 0.9 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.8 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.5 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.1 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.0 0.2 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.2 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.3 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.7 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 0.3 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.0 1.1 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.4 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.1 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.4 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.1 GO:0031800 type 3 metabotropic glutamate receptor binding(GO:0031800)
0.0 0.2 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.7 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.1 GO:0015410 manganese-transporting ATPase activity(GO:0015410)
0.0 2.7 GO:0005262 calcium channel activity(GO:0005262)
0.0 0.5 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.3 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.2 GO:0045545 syndecan binding(GO:0045545)
0.0 0.3 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.1 GO:0004008 copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682)
0.0 0.3 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.9 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.4 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.7 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 1.0 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.3 GO:0019956 chemokine binding(GO:0019956)
0.0 0.4 GO:0005542 folic acid binding(GO:0005542)
0.0 0.8 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.4 GO:0005123 death receptor binding(GO:0005123)
0.0 0.3 GO:0051861 glycolipid binding(GO:0051861)
0.0 2.2 GO:0005178 integrin binding(GO:0005178)
0.0 0.6 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 2.8 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.4 GO:0005112 Notch binding(GO:0005112)
0.0 0.6 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.1 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.0 0.5 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.1 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.4 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.4 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 1.3 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.3 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 3.1 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 0.2 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.7 GO:0002039 p53 binding(GO:0002039)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.5 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 3.4 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.7 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.3 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.7 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.4 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 1.1 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.8 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 2.5 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 1.7 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.7 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.8 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.4 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 0.2 PID FOXO PATHWAY FoxO family signaling
0.0 0.6 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 1.5 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 1.8 PID P73PATHWAY p73 transcription factor network
0.0 1.5 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.8 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.3 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.6 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.7 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.4 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.6 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.4 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 2.5 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.5 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.3 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 7.8 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.1 1.2 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 2.6 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.1 0.3 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.1 1.4 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 0.4 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 0.3 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.1 1.3 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 1.2 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.6 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.8 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.8 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.4 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 1.1 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 1.6 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.6 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.5 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.4 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.9 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.2 REACTOME OPSINS Genes involved in Opsins
0.0 0.2 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.5 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 0.3 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 0.6 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.5 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.2 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.7 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.0 1.2 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.3 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.9 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 0.2 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.4 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.4 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.5 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases