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12D miR HR13_24

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Results for Tead1

Z-value: 0.53

Motif logo

Transcription factors associated with Tead1

Gene Symbol Gene ID Gene Info
ENSMUSG00000055320.10 TEA domain family member 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Tead1mm10_v2_chr7_+_112742025_1127420600.412.1e-01Click!

Activity profile of Tead1 motif

Sorted Z-values of Tead1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_34255325 1.16 ENSMUST00000039631.8
actin, alpha 2, smooth muscle, aorta
chr1_-_87394721 0.82 ENSMUST00000113212.3
potassium inwardly-rectifying channel, subfamily J, member 13
chr8_-_47990535 0.71 ENSMUST00000057561.7
WW, C2 and coiled-coil domain containing 2
chr10_-_87493651 0.53 ENSMUST00000020243.7
achaete-scute complex homolog 1 (Drosophila)
chr1_+_135766085 0.53 ENSMUST00000038945.5
pleckstrin homology-like domain, family A, member 3
chr4_-_118544010 0.48 ENSMUST00000128098.1
transmembrane protein 125
chr15_+_6386598 0.45 ENSMUST00000080880.5
ENSMUST00000110664.2
ENSMUST00000110663.2
ENSMUST00000161812.1
ENSMUST00000160134.1
disabled 2, mitogen-responsive phosphoprotein
chr9_-_44713196 0.43 ENSMUST00000144251.1
ENSMUST00000156918.1
pleckstrin homology-like domain, family B, member 1
chr19_-_4439388 0.43 ENSMUST00000117462.1
ENSMUST00000048197.3
ras homolog gene family, member D
chr2_-_32353247 0.38 ENSMUST00000078352.5
ENSMUST00000113352.2
ENSMUST00000113365.1
dynamin 1
chr10_+_24595434 0.36 ENSMUST00000020171.5
connective tissue growth factor
chr2_+_55437100 0.33 ENSMUST00000112633.2
ENSMUST00000112632.1
potassium inwardly-rectifying channel, subfamily J, member 3
chr11_-_32222233 0.33 ENSMUST00000150381.1
ENSMUST00000144902.1
ENSMUST00000020524.8
rhomboid family 1 (Drosophila)
chr11_-_100970887 0.32 ENSMUST00000060792.5
polymerase I and transcript release factor
chr6_+_34598500 0.30 ENSMUST00000079391.3
ENSMUST00000142512.1
caldesmon 1
chr9_-_16378231 0.30 ENSMUST00000082170.5
FAT tumor suppressor homolog 3 (Drosophila)
chr11_-_5381734 0.29 ENSMUST00000172492.1
zinc and ring finger 3
chr2_+_156775409 0.29 ENSMUST00000088552.6
myosin, light polypeptide 9, regulatory
chr6_+_34598530 0.28 ENSMUST00000115027.1
ENSMUST00000115026.1
caldesmon 1
chr16_-_4559720 0.28 ENSMUST00000005862.7
transcription factor AP4
chr3_-_113258837 0.27 ENSMUST00000098673.3
amylase 2a5
chr6_-_128124312 0.26 ENSMUST00000127105.1
tetraspanin 9
chr18_+_61953048 0.25 ENSMUST00000051720.5
SH3 domain and tetratricopeptide repeats 2
chr1_+_51289106 0.24 ENSMUST00000051572.6
serum deprivation response
chr10_+_24595623 0.24 ENSMUST00000176228.1
ENSMUST00000129142.1
connective tissue growth factor
chr14_-_54577578 0.24 ENSMUST00000054487.8
ajuba LIM protein
chr8_+_57511833 0.23 ENSMUST00000067925.6
high mobility group box 2
chr6_+_17306415 0.22 ENSMUST00000150901.1
caveolin 1, caveolae protein
chr15_+_78842632 0.21 ENSMUST00000059619.1
CDC42 effector protein (Rho GTPase binding) 1
chr6_+_17307040 0.20 ENSMUST00000123439.1
caveolin 1, caveolae protein
chr6_+_17306335 0.19 ENSMUST00000007799.6
ENSMUST00000115456.1
ENSMUST00000115455.2
ENSMUST00000130505.1
caveolin 1, caveolae protein
chr1_+_193301953 0.19 ENSMUST00000016315.9
laminin, beta 3
chr4_+_149545102 0.16 ENSMUST00000105692.1
catenin beta interacting protein 1
chr17_-_28350747 0.16 ENSMUST00000080572.7
ENSMUST00000156862.1
TEA domain family member 3
chr10_+_28074813 0.15 ENSMUST00000166468.1
protein tyrosine phosphatase, receptor type, K
chr11_-_69398226 0.15 ENSMUST00000050140.5
transmembrane protein 88
chr14_+_30879257 0.15 ENSMUST00000040715.6
musculoskeletal, embryonic nuclear protein 1
chr13_-_74376566 0.14 ENSMUST00000091481.2
zinc finger protein 72
chr19_-_42128982 0.14 ENSMUST00000161873.1
arginine vasopressin-induced 1
chr1_+_189728264 0.14 ENSMUST00000097442.2
protein tyrosine phosphatase, non-receptor type 14
chr4_-_43558386 0.13 ENSMUST00000130353.1
talin 1
chr12_-_98737405 0.13 ENSMUST00000170188.1
protein tyrosine phosphatase, non-receptor type 21
chr9_-_107609215 0.12 ENSMUST00000102532.3
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
chr2_-_164857542 0.12 ENSMUST00000109316.1
ENSMUST00000156255.1
ENSMUST00000128110.1
ENSMUST00000109317.3
phospholipid transfer protein
chr5_+_136967859 0.12 ENSMUST00000001790.5
claudin 15
chr6_+_88724828 0.11 ENSMUST00000089449.2
monoglyceride lipase
chr11_+_62820469 0.11 ENSMUST00000108703.1
tripartite motif-containing 16
chr5_+_76951382 0.11 ENSMUST00000141687.1
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoribosylaminoimidazole, succinocarboxamide synthetase
chr4_-_62360524 0.11 ENSMUST00000107461.1
ENSMUST00000084528.3
FK506 binding protein 15
chr15_-_36283105 0.11 ENSMUST00000022890.8
ring finger protein 19A
chr8_-_95306585 0.11 ENSMUST00000119870.2
ENSMUST00000093268.4
cyclic nucleotide gated channel beta 1
chr17_-_35701937 0.10 ENSMUST00000155628.1
discoidin domain receptor family, member 1
chr12_+_8973892 0.09 ENSMUST00000085745.6
ENSMUST00000111113.2
WD repeat domain 35
chr3_+_89831352 0.09 ENSMUST00000050401.5
src homology 2 domain-containing transforming protein E
chr9_-_107609182 0.09 ENSMUST00000102531.1
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
chr19_-_42129043 0.09 ENSMUST00000018965.3
arginine vasopressin-induced 1
chr8_-_105966038 0.09 ENSMUST00000116429.2
ENSMUST00000034370.9
solute carrier family 12, member 4
chr5_-_115300912 0.09 ENSMUST00000112090.1
dynein light chain LC8-type 1
chr4_-_62360436 0.08 ENSMUST00000084527.3
ENSMUST00000098033.3
FK506 binding protein 15
chr11_+_62077018 0.08 ENSMUST00000092415.5
sperm antigen with calponin homology and coiled-coil domains 1
chr9_+_38752796 0.08 ENSMUST00000074740.2
olfactory receptor 920
chr10_-_42276688 0.08 ENSMUST00000175881.1
ENSMUST00000056974.3
forkhead box O3
chr1_-_168432270 0.08 ENSMUST00000072863.4
pre B cell leukemia homeobox 1
chr11_+_115933282 0.08 ENSMUST00000140991.1
SAP30 binding protein
chr5_-_115300957 0.07 ENSMUST00000009157.3
dynein light chain LC8-type 1
chr4_+_15265798 0.07 ENSMUST00000062684.8
transmembrane protein 64
chr7_-_28372233 0.07 ENSMUST00000094644.4
pleckstrin homology domain containing, family G (with RhoGef domain) member 2
chr15_-_76009440 0.07 ENSMUST00000170153.1
family with sequence similarity 83, member H
chrX_+_152178945 0.07 ENSMUST00000096275.4
IQ motif and Sec7 domain 2
chr5_+_21645813 0.07 ENSMUST00000148873.1
ENSMUST00000072896.6
armadillo repeat containing 10
chr17_-_28350600 0.07 ENSMUST00000114799.1
TEA domain family member 3
chr3_-_57575760 0.07 ENSMUST00000029380.7
WW domain containing transcription regulator 1
chr8_+_45627946 0.06 ENSMUST00000145458.1
sorbin and SH3 domain containing 2
chr6_+_88724667 0.06 ENSMUST00000163271.1
monoglyceride lipase
chr11_+_120721452 0.06 ENSMUST00000018156.5
RAS-related C3 botulinum substrate 3
chr19_-_57197435 0.06 ENSMUST00000111550.1
actin-binding LIM protein 1
chr8_-_70700070 0.06 ENSMUST00000116172.1
predicted gene 11175
chr11_-_115933464 0.06 ENSMUST00000021097.3
RecQ protein-like 5
chr6_+_145934113 0.05 ENSMUST00000032383.7
sarcospan
chr6_-_134887783 0.05 ENSMUST00000066107.6
G protein-coupled receptor 19
chr6_+_120364094 0.05 ENSMUST00000100996.3
ENSMUST00000005108.7
lysine (K)-specific demethylase 5A
chr7_-_28372494 0.05 ENSMUST00000119990.1
pleckstrin homology domain containing, family G (with RhoGef domain) member 2
chr11_+_70432627 0.05 ENSMUST00000084954.6
ENSMUST00000108568.3
ENSMUST00000079056.2
ENSMUST00000102564.4
ENSMUST00000124943.1
ENSMUST00000150076.1
ENSMUST00000102563.1
arrestin, beta 2
chr17_+_16972910 0.05 ENSMUST00000071374.5
cDNA sequence BC002059
chr10_-_127288999 0.04 ENSMUST00000119078.1
methyl-CpG binding domain protein 6
chr2_+_120404757 0.04 ENSMUST00000135074.1
glucosidase, alpha; neutral C
chr4_-_120287349 0.04 ENSMUST00000102656.3
forkhead box O6
chr7_+_114745685 0.04 ENSMUST00000136645.1
ENSMUST00000169913.1
inscuteable homolog (Drosophila)
chr9_-_95750335 0.04 ENSMUST00000053785.3
transient receptor potential cation channel, subfamily C, member 1
chr17_-_35702040 0.04 ENSMUST00000166980.2
ENSMUST00000145900.1
discoidin domain receptor family, member 1
chr10_-_42276744 0.04 ENSMUST00000105502.1
ENSMUST00000105501.1
forkhead box O3
chr11_-_60115226 0.04 ENSMUST00000130746.1
RIKEN cDNA 4930412M03 gene
chr4_+_59189240 0.03 ENSMUST00000030074.7
UDP-glucose ceramide glucosyltransferase
chr4_+_45203921 0.03 ENSMUST00000107804.1
FERM and PDZ domain containing 1
chr17_+_86167777 0.03 ENSMUST00000097275.2
protein kinase C, epsilon
chr17_-_71002017 0.02 ENSMUST00000128179.1
ENSMUST00000150456.1
myosin, light chain 12A, regulatory, non-sarcomeric
chr10_+_126978690 0.02 ENSMUST00000105256.2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
chr10_-_127288851 0.02 ENSMUST00000156208.1
ENSMUST00000026476.6
methyl-CpG binding domain protein 6
chr16_-_97851796 0.02 ENSMUST00000121584.1
PR domain containing 15
chr2_-_120404058 0.02 ENSMUST00000090042.5
ENSMUST00000110729.1
ENSMUST00000090046.5
transmembrane protein 87A
chr19_-_57197377 0.02 ENSMUST00000111546.1
actin-binding LIM protein 1
chr8_-_122551316 0.02 ENSMUST00000067252.7
piezo-type mechanosensitive ion channel component 1
chr7_+_24904384 0.02 ENSMUST00000117419.1
Rho guanine nucleotide exchange factor (GEF) 1
chr19_-_57197496 0.01 ENSMUST00000111544.1
actin-binding LIM protein 1
chr17_-_13052280 0.01 ENSMUST00000091648.2
G protein-coupled receptor 31, D17Leh66b region
chr11_-_83429455 0.01 ENSMUST00000052521.2
growth arrest-specific 2 like 2
chr6_+_146888481 0.01 ENSMUST00000016631.7
ENSMUST00000111623.2
PTPRF interacting protein, binding protein 1 (liprin beta 1)
chr11_+_97415527 0.01 ENSMUST00000121799.1
Rho GTPase activating protein 23
chr11_+_21239279 0.00 ENSMUST00000006221.7
ENSMUST00000109578.1
vacuolar protein sorting 54 (yeast)
chr8_-_4325096 0.00 ENSMUST00000098950.4
ELAV (embryonic lethal, abnormal vision)-like 1 (Hu antigen R)
chr9_-_65391652 0.00 ENSMUST00000068307.3
kelch repeat and BTB (POZ) domain containing 13
chr1_+_156310716 0.00 ENSMUST00000027896.4
nephrosis 2, podocin
chr9_-_8004585 0.00 ENSMUST00000086580.5
ENSMUST00000065353.6
yes-associated protein 1
chr5_-_21645541 0.00 ENSMUST00000115234.1
ENSMUST00000051358.4
F-box and leucine-rich repeat protein 13
chr6_+_113458765 0.00 ENSMUST00000101065.1
ENSMUST00000053569.4
interleukin 17 receptor E

Network of associatons between targets according to the STRING database.

First level regulatory network of Tead1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0060166 olfactory pit development(GO:0060166)
0.1 1.2 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.1 0.6 GO:1903609 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
0.1 0.6 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)
0.1 0.4 GO:0035026 positive regulation of aldosterone metabolic process(GO:0032346) positive regulation of aldosterone biosynthetic process(GO:0032349) leading edge cell differentiation(GO:0035026)
0.1 0.4 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.1 0.4 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.0 0.3 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.0 0.3 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 0.2 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.0 0.4 GO:1904261 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.0 0.2 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.0 0.3 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.0 0.2 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.0 0.1 GO:1902732 positive regulation of chondrocyte proliferation(GO:1902732)
0.0 0.1 GO:0042360 vitamin E metabolic process(GO:0042360)
0.0 0.1 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.1 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.0 0.1 GO:0044789 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.0 0.2 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.0 0.1 GO:0040010 positive regulation of growth rate(GO:0040010)
0.0 0.2 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.1 GO:1901300 positive regulation of hydrogen peroxide-mediated programmed cell death(GO:1901300)
0.0 0.0 GO:0031064 negative regulation of histone deacetylation(GO:0031064)
0.0 0.3 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 0.2 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.0 0.1 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.0 0.1 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.2 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 0.1 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 0.4 GO:0010107 potassium ion import(GO:0010107)
0.0 0.1 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.2 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.1 0.4 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1 0.6 GO:0030478 actin cap(GO:0030478)
0.0 0.2 GO:0005610 laminin-5 complex(GO:0005610)
0.0 0.6 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.4 GO:0045180 basal cortex(GO:0045180)
0.0 0.6 GO:0043196 varicosity(GO:0043196)
0.0 0.3 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.6 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.2 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.1 GO:0030991 intraciliary transport particle A(GO:0030991)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.1 0.3 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.0 GO:0031762 alpha-1A adrenergic receptor binding(GO:0031691) alpha-1B adrenergic receptor binding(GO:0031692) follicle-stimulating hormone receptor binding(GO:0031762)
0.0 0.4 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.0 0.3 GO:0004556 alpha-amylase activity(GO:0004556)
0.0 0.5 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.4 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.2 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.6 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.4 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.2 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.1 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 0.2 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.1 GO:1990254 keratin filament binding(GO:1990254)
0.0 0.8 GO:0070888 E-box binding(GO:0070888)
0.0 0.1 GO:0019966 interleukin-1 binding(GO:0019966)
0.0 0.2 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.0 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.0 0.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.1 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.1 GO:0030274 LIM domain binding(GO:0030274)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 1.1 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.1 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 0.4 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.2 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.8 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.8 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.6 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.2 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.3 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination