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12D miR HR13_24

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Results for Hnf1b

Z-value: 1.34

Motif logo

Transcription factors associated with Hnf1b

Gene Symbol Gene ID Gene Info
ENSMUSG00000020679.5 HNF1 homeobox B

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hnf1bmm10_v2_chr11_+_83852135_83852242-0.614.9e-02Click!

Activity profile of Hnf1b motif

Sorted Z-values of Hnf1b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_158814469 7.48 ENSMUST00000161589.2
pappalysin 2
chr5_+_90518932 3.86 ENSMUST00000113179.2
ENSMUST00000128740.1
afamin
chrX_-_139085211 3.41 ENSMUST00000033626.8
ENSMUST00000060824.3
serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
chr2_-_62412219 2.82 ENSMUST00000047812.7
dipeptidylpeptidase 4
chrX_-_139085230 2.77 ENSMUST00000152457.1
serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
chrX_+_164140447 2.62 ENSMUST00000073973.4
angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
chr16_-_45492962 2.54 ENSMUST00000114585.2
predicted gene 609
chr12_+_59095653 2.53 ENSMUST00000021384.4
melanoma inhibitory activity 2
chr15_+_10215955 2.24 ENSMUST00000130720.1
prolactin receptor
chr7_-_101870711 2.23 ENSMUST00000151706.1
folate receptor 1 (adult)
chr13_+_89540636 2.22 ENSMUST00000022108.7
hyaluronan and proteoglycan link protein 1
chr11_+_3983704 2.18 ENSMUST00000063004.7
galactose-3-O-sulfotransferase 1
chr11_+_3983636 2.08 ENSMUST00000078757.1
galactose-3-O-sulfotransferase 1
chr11_+_115834314 1.99 ENSMUST00000173289.1
ENSMUST00000137900.1
lethal giant larvae homolog 2 (Drosophila)
chr3_+_115080965 1.97 ENSMUST00000051309.8
olfactomedin 3
chr2_-_35100677 1.97 ENSMUST00000045776.4
ENSMUST00000113050.3
expressed sequence AI182371
chr3_-_144819494 1.96 ENSMUST00000029929.7
chloride channel calcium activated 2
chr17_+_23660477 1.93 ENSMUST00000062967.8
coiled-coil domain containing 64B
chr1_-_20617992 1.89 ENSMUST00000088448.5
polycystic kidney and hepatic disease 1
chr12_-_103631404 1.83 ENSMUST00000121625.1
ENSMUST00000044231.5
serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
chr4_+_138967112 1.79 ENSMUST00000116094.2
ring finger protein 186
chr8_-_107065632 1.77 ENSMUST00000034393.5
transmembrane emp24 protein transport domain containing 6
chr8_+_70724064 1.76 ENSMUST00000034307.7
ENSMUST00000110095.2
phosphodiesterase 4C, cAMP specific
chr16_+_96361654 1.75 ENSMUST00000113794.1
immunoglobulin superfamily, member 5
chrX_+_52791179 1.71 ENSMUST00000101588.1
coiled-coil domain containing 160
chr16_+_96361749 1.69 ENSMUST00000000163.6
ENSMUST00000081093.3
ENSMUST00000113795.1
immunoglobulin superfamily, member 5
chr12_+_58211772 1.63 ENSMUST00000110671.2
ENSMUST00000044299.2
somatostatin receptor 1
chr1_+_125676969 1.61 ENSMUST00000027581.6
G protein-coupled receptor 39
chr5_+_102845007 1.58 ENSMUST00000070000.4
Rho GTPase activating protein 24
chr14_-_49245389 1.56 ENSMUST00000130853.1
ENSMUST00000022398.7
RIKEN cDNA 1700011H14 gene
chr17_+_57062231 1.37 ENSMUST00000097299.3
ENSMUST00000169543.1
ENSMUST00000163763.1
crumbs homolog 3 (Drosophila)
chrX_+_140907602 1.28 ENSMUST00000033806.4
V-set and immunoglobulin domain containing 1
chr1_+_40439627 1.20 ENSMUST00000097772.3
interleukin 1 receptor-like 1
chr1_-_172895048 1.19 ENSMUST00000027824.5
serum amyloid P-component
chr6_-_116716888 1.19 ENSMUST00000056623.6
transmembrane protein 72
chr6_-_137571007 1.17 ENSMUST00000100841.2
epidermal growth factor receptor pathway substrate 8
chr4_+_19280850 1.16 ENSMUST00000102999.1
cyclic nucleotide gated channel beta 3
chr10_-_89533550 1.12 ENSMUST00000105297.1
nuclear receptor subfamily 1, group H, member 4
chr16_+_24448082 1.10 ENSMUST00000078988.2
LIM domain containing preferred translocation partner in lipoma
chr19_+_60889749 1.06 ENSMUST00000003313.8
G protein-coupled receptor kinase 5
chr3_+_129836729 1.06 ENSMUST00000077918.5
complement component factor i
chr13_-_23914998 1.05 ENSMUST00000021769.8
ENSMUST00000110407.2
solute carrier family 17 (sodium phosphate), member 4
chr13_-_53286052 1.05 ENSMUST00000021918.8
receptor tyrosine kinase-like orphan receptor 2
chr9_+_109096659 1.01 ENSMUST00000130366.1
plexin B1
chr19_-_57197556 1.00 ENSMUST00000099294.2
actin-binding LIM protein 1
chr5_-_87569023 0.98 ENSMUST00000113314.2
sulfotransferase family 1D, member 1
chr19_+_42045792 0.96 ENSMUST00000172244.1
ENSMUST00000081714.4
4-hydroxy-2-oxoglutarate aldolase 1
chr3_-_69859875 0.94 ENSMUST00000051239.7
ENSMUST00000171529.1
serine palmitoyltransferase, small subunit B
chr1_+_58795371 0.89 ENSMUST00000027189.8
caspase 8
chr6_-_52240841 0.88 ENSMUST00000121043.1
homeobox A10
chr18_+_33464163 0.86 ENSMUST00000097634.3
predicted gene 10549
chrX_+_107792583 0.84 ENSMUST00000101292.2
family with sequence similarity 46, member D
chr4_+_19818722 0.84 ENSMUST00000035890.7
solute carrier family 7, (cationic amino acid transporter, y+ system) member 13
chr1_+_88166004 0.83 ENSMUST00000097659.4
UDP glucuronosyltransferase 1 family, polypeptide A5
chr1_+_40439767 0.80 ENSMUST00000173514.1
interleukin 1 receptor-like 1
chr7_-_119895446 0.79 ENSMUST00000098080.2
DCN1, defective in cullin neddylation 1, domain containing 3 (S. cerevisiae)
chr6_-_129876659 0.79 ENSMUST00000014687.4
ENSMUST00000122219.1
killer cell lectin-like receptor, subfamily A, member 17
chr1_+_88070765 0.79 ENSMUST00000073772.4
UDP glucuronosyltransferase 1 family, polypeptide A9
chr1_+_88138364 0.76 ENSMUST00000014263.4
UDP glucuronosyltransferase 1 family, polypeptide A6A
chr17_+_57062486 0.74 ENSMUST00000163628.1
crumbs homolog 3 (Drosophila)
chr4_-_111898695 0.73 ENSMUST00000102720.1
solute carrier family 5 (sodium/glucose cotransporter), member 9
chr1_+_88211956 0.71 ENSMUST00000073049.6
UDP glucuronosyltransferase 1 family, polypeptide A1
chr19_+_43782181 0.69 ENSMUST00000026208.4
ATP-binding cassette, sub-family C (CFTR/MRP), member 2
chr1_+_88055467 0.68 ENSMUST00000173325.1
UDP glycosyltransferase 1 family, polypeptide A10
chr9_+_54538984 0.68 ENSMUST00000060242.5
ENSMUST00000118413.1
SH2 domain containing 7
chr9_+_72958785 0.67 ENSMUST00000098567.2
ENSMUST00000034734.8
dyslexia susceptibility 1 candidate 1 homolog (human)
chrX_+_101376359 0.67 ENSMUST00000119080.1
gap junction protein, beta 1
chr11_+_78037931 0.64 ENSMUST00000072289.5
ENSMUST00000100784.2
flotillin 2
chr1_+_88055377 0.63 ENSMUST00000138182.1
ENSMUST00000113142.3
UDP glycosyltransferase 1 family, polypeptide A10
chr9_+_120149733 0.62 ENSMUST00000068698.7
ENSMUST00000093773.1
ENSMUST00000111627.1
myelin-associated oligodendrocytic basic protein
chr11_+_78037959 0.62 ENSMUST00000073660.6
flotillin 2
chr5_+_150952607 0.61 ENSMUST00000078856.6
klotho
chr19_-_46672883 0.61 ENSMUST00000026012.7
cytochrome P450, family 17, subfamily a, polypeptide 1
chr4_-_53262547 0.60 ENSMUST00000098075.2
expressed sequence AI427809
chr7_-_45062393 0.59 ENSMUST00000129101.1
proline-rich Gla (G-carboxyglutamic acid) polypeptide 2
chr5_-_108675569 0.58 ENSMUST00000051757.7
solute carrier family 26 (sulfate transporter), member 1
chr18_-_66022580 0.56 ENSMUST00000143990.1
lectin, mannose-binding, 1
chr4_-_140617062 0.56 ENSMUST00000154979.1
Rho guanine nucleotide exchange factor (GEF) 10-like
chr12_+_76533540 0.55 ENSMUST00000075249.4
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr2_-_164221605 0.54 ENSMUST00000018355.4
ENSMUST00000109376.2
WAP four-disulfide core domain 15B
chr14_+_34085978 0.54 ENSMUST00000022519.8
annexin A8
chr12_-_76795489 0.53 ENSMUST00000082431.3
glutathione peroxidase 2
chr13_+_23807027 0.53 ENSMUST00000006786.4
ENSMUST00000099697.2
solute carrier family 17 (sodium phosphate), member 2
chr3_-_113291449 0.52 ENSMUST00000179568.1
amylase 2a4
chr3_-_72967854 0.51 ENSMUST00000167334.1
sucrase isomaltase (alpha-glucosidase)
chr13_-_21453714 0.51 ENSMUST00000032820.7
ENSMUST00000110485.1
zinc finger and SCAN domain containing 26
chr4_+_150853919 0.51 ENSMUST00000073600.2
ERBB receptor feedback inhibitor 1
chr15_+_99393574 0.50 ENSMUST00000162624.1
transmembrane BAX inhibitor motif containing 6
chr18_+_55057557 0.50 ENSMUST00000181765.1
predicted gene 4221
chr4_-_108144986 0.48 ENSMUST00000130776.1
sterol carrier protein 2, liver
chr15_+_85510812 0.47 ENSMUST00000079690.2
predicted pseudogene 4825
chr11_+_115912001 0.47 ENSMUST00000132961.1
small integral membrane protein 6
chr3_-_116712644 0.47 ENSMUST00000029569.2
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member 3
chr17_+_47737030 0.46 ENSMUST00000086932.3
transcription factor EB
chr19_-_11856001 0.45 ENSMUST00000079875.3
olfactory receptor 1418
chr15_+_99393610 0.44 ENSMUST00000159531.1
transmembrane BAX inhibitor motif containing 6
chr11_+_101367542 0.43 ENSMUST00000019469.2
glucose-6-phosphatase, catalytic
chr18_-_43737186 0.42 ENSMUST00000025381.2
serine peptidase inhibitor, Kazal type 3
chr1_-_187215421 0.42 ENSMUST00000110945.3
ENSMUST00000183931.1
ENSMUST00000027908.6
spermatogenesis associated 17
chr5_-_38491948 0.42 ENSMUST00000129099.1
solute carrier family 2 (facilitated glucose transporter), member 9
chr3_-_98457031 0.42 ENSMUST00000167753.1
predicted gene 4450
chr3_-_89365233 0.40 ENSMUST00000070820.6
DC-STAMP domain containing 1
chr4_-_104876383 0.40 ENSMUST00000064873.8
ENSMUST00000106808.3
ENSMUST00000048947.8
complement component 8, alpha polypeptide
chr15_-_50890396 0.40 ENSMUST00000185183.1
trichorhinophalangeal syndrome I (human)
chr16_+_33251415 0.40 ENSMUST00000023502.4
sorting nexin 4
chr14_+_26894557 0.39 ENSMUST00000090337.4
ENSMUST00000165929.2
ankyrin repeat and SOCS box-containing 14
chr3_-_98564038 0.39 ENSMUST00000058728.5
predicted gene 10681
chr19_+_27217011 0.38 ENSMUST00000164746.1
ENSMUST00000172302.1
very low density lipoprotein receptor
chr3_-_116712696 0.38 ENSMUST00000169530.1
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member 3
chr1_+_130731963 0.37 ENSMUST00000039323.6
expressed sequence AA986860
chr8_-_122476036 0.37 ENSMUST00000014614.3
ring finger protein 166
chr8_-_67974567 0.35 ENSMUST00000098696.3
ENSMUST00000038959.9
ENSMUST00000093469.4
pleckstrin and Sec7 domain containing 3
chr14_+_79515618 0.35 ENSMUST00000110835.1
E74-like factor 1
chr1_+_181051232 0.34 ENSMUST00000036819.6
RIKEN cDNA 9130409I23 gene
chr11_+_78465697 0.33 ENSMUST00000001126.3
solute carrier family 46, member 1
chr10_-_10472314 0.32 ENSMUST00000179956.1
ENSMUST00000172530.1
ENSMUST00000132573.1
androglobin
chr19_-_57197496 0.32 ENSMUST00000111544.1
actin-binding LIM protein 1
chr14_+_34086008 0.32 ENSMUST00000120077.1
annexin A8
chr3_-_37232565 0.31 ENSMUST00000161015.1
ENSMUST00000029273.1
interleukin 21
chr19_+_56287911 0.30 ENSMUST00000095948.4
hyaluronic acid binding protein 2
chr7_+_141216626 0.30 ENSMUST00000141804.1
ENSMUST00000148975.1
Ras association (RalGDS/AF-6) domain family (N-terminal) member 7
chr10_+_102159000 0.30 ENSMUST00000020039.6
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr11_-_78422217 0.29 ENSMUST00000001122.5
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
chr11_+_44518959 0.29 ENSMUST00000019333.3
ring finger protein 145
chr2_+_91265252 0.29 ENSMUST00000028691.6
ADP-ribosylation factor GTPase activating protein 2
chr2_+_70039114 0.28 ENSMUST00000060208.4
myosin IIIB
chr9_+_67840386 0.27 ENSMUST00000077879.5
vacuolar protein sorting 13C (yeast)
chr7_-_28962265 0.27 ENSMUST00000068045.7
actinin alpha 4
chr4_+_44943727 0.27 ENSMUST00000154177.1
predicted gene 12678
chr7_+_24897381 0.27 ENSMUST00000003469.7
CD79A antigen (immunoglobulin-associated alpha)
chr1_-_187215454 0.27 ENSMUST00000183819.1
spermatogenesis associated 17
chr4_-_139968026 0.27 ENSMUST00000105031.2
kelch domain containing 7A
chr13_+_23839401 0.26 ENSMUST00000039721.7
ENSMUST00000166467.1
solute carrier family 17 (sodium phosphate), member 3
chr15_-_57265126 0.26 ENSMUST00000137764.1
ENSMUST00000022995.6
solute carrier family 22 (organic cation transporter), member 22
chr3_-_144849301 0.25 ENSMUST00000159989.1
chloride channel calcium activated 4
chr11_+_83852135 0.24 ENSMUST00000146786.1
HNF1 homeobox B
chr4_+_99030946 0.24 ENSMUST00000030280.6
angiopoietin-like 3
chr5_-_114444036 0.24 ENSMUST00000031560.7
methylmalonic aciduria (cobalamin deficiency) type B homolog (human)
chr9_-_44767792 0.24 ENSMUST00000034607.9
archain 1
chr8_-_8690493 0.23 ENSMUST00000048545.8
arginine and glutamate rich 1
chr7_-_28962223 0.22 ENSMUST00000127210.1
actinin alpha 4
chr5_-_106926245 0.22 ENSMUST00000117588.1
HFM1, ATP-dependent DNA helicase homolog (S. cerevisiae)
chr12_+_4769375 0.22 ENSMUST00000178879.1
profilin family, member 4
chr5_-_87254804 0.21 ENSMUST00000075858.3
UDP glucuronosyltransferase 2 family, polypeptide B37
chr7_+_100537192 0.21 ENSMUST00000120454.1
cytochrome c oxidase assembly factor 4
chr13_+_23839445 0.20 ENSMUST00000091698.4
ENSMUST00000110422.1
solute carrier family 17 (sodium phosphate), member 3
chr5_-_100373484 0.19 ENSMUST00000182433.1
Sec31 homolog A (S. cerevisiae)
chr8_-_104624266 0.19 ENSMUST00000163783.2
cadherin 16
chrX_+_164090187 0.19 ENSMUST00000015545.3
transmembrane protein 27
chrX_+_101449078 0.19 ENSMUST00000033674.5
integrin beta 1 binding protein 2
chr9_-_71163224 0.19 ENSMUST00000074465.2
aquaporin 9
chr3_+_69222412 0.18 ENSMUST00000183126.1
ADP-ribosylation factor-like 14
chr14_+_48446128 0.18 ENSMUST00000124720.1
transmembrane protein 260
chr7_+_90348699 0.17 ENSMUST00000107211.1
ENSMUST00000107210.1
synaptotagmin-like 2
chr7_+_131032061 0.17 ENSMUST00000084509.3
deleted in malignant brain tumors 1
chr7_-_29505447 0.17 ENSMUST00000183096.1
ENSMUST00000085809.4
signal-induced proliferation-associated 1 like 3
chr6_+_134920401 0.17 ENSMUST00000067327.4
ENSMUST00000003115.6
cyclin-dependent kinase inhibitor 1B
chr15_-_36879816 0.16 ENSMUST00000100713.2
predicted gene 10384
chr7_+_141215852 0.16 ENSMUST00000046890.5
ENSMUST00000133763.1
Ras association (RalGDS/AF-6) domain family (N-terminal) member 7
chr19_+_39113898 0.16 ENSMUST00000087234.2
cytochrome P450, family 2, subfamily c, polypeptide 66
chr6_-_128275577 0.15 ENSMUST00000130454.1
TEA domain family member 4
chr16_-_79091078 0.15 ENSMUST00000023566.4
ENSMUST00000060402.5
transmembrane protease, serine 15
chr11_-_75937726 0.15 ENSMUST00000121287.1
rabphilin 3A-like (without C2 domains)
chr1_+_133309778 0.15 ENSMUST00000094557.4
ENSMUST00000183457.1
ENSMUST00000183738.1
ENSMUST00000185157.1
ENSMUST00000184603.1
golgi transport 1 homolog A (S. cerevisiae)
KiSS-1 metastasis-suppressor
KISS1 isoform e
chr14_+_48446340 0.15 ENSMUST00000111735.2
transmembrane protein 260
chr7_+_120173847 0.15 ENSMUST00000033201.5
ankyrin repeat and sterile alpha motif domain containing 4B
chr7_+_141746736 0.15 ENSMUST00000026590.8
mucin 2
chr6_+_90333270 0.14 ENSMUST00000164761.1
ENSMUST00000046128.9
urocanase domain containing 1
chr5_-_87535113 0.14 ENSMUST00000120150.1
sulfotransferase family 1B, member 1
chr11_+_70519183 0.14 ENSMUST00000057685.2
glycolipid transfer protein domain containing 2
chr6_-_129100903 0.14 ENSMUST00000032258.6
C-type lectin domain family 2, member e
chr19_-_30549516 0.14 ENSMUST00000025803.8
dickkopf homolog 1 (Xenopus laevis)
chr6_+_142345648 0.14 ENSMUST00000041852.7
pyridine nucleotide-disulphide oxidoreductase domain 1
chr13_+_66932802 0.14 ENSMUST00000021990.3
phosphatidylserine synthase 1
chr14_-_36919513 0.14 ENSMUST00000182042.1
coiled-coil serine rich 2
chr18_+_20310738 0.13 ENSMUST00000077146.3
desmoglein 1 alpha
chr6_-_24168083 0.13 ENSMUST00000031713.8
solute carrier family 13 (sodium/sulfate symporters), member 1
chr2_+_151494274 0.13 ENSMUST00000028949.9
ENSMUST00000103160.4
NSFL1 (p97) cofactor (p47)
chr14_+_61309753 0.13 ENSMUST00000055159.7
ADP-ribosylation factor-like 11
chr10_-_30842765 0.12 ENSMUST00000019924.8
hairy/enhancer-of-split related with YRPW motif 2
chr2_+_173737492 0.12 ENSMUST00000067530.4
vesicle-associated membrane protein, associated protein B and C
chr19_+_5878622 0.12 ENSMUST00000136833.1
ENSMUST00000141362.1
solute carrier family 25, member 45
chr13_-_73678005 0.12 ENSMUST00000022105.7
ENSMUST00000109680.2
ENSMUST00000109679.2
solute carrier family 6 (neurotransmitter transporter), member 18
chr6_-_41704339 0.12 ENSMUST00000031899.8
Kell blood group
chr8_+_68276567 0.11 ENSMUST00000066594.3
SH2 domain containing 4A
chr15_-_101680281 0.11 ENSMUST00000023786.5
keratin 6B
chr6_+_52177498 0.11 ENSMUST00000070587.3
RIKEN cDNA 5730596B20 gene
chr11_+_110968016 0.11 ENSMUST00000106636.1
ENSMUST00000180023.1
potassium inwardly-rectifying channel, subfamily J, member 16
chr19_-_58794436 0.10 ENSMUST00000028299.4
RIKEN cDNA 1700019N19 gene
chr5_-_121527186 0.10 ENSMUST00000152270.1
MAP kinase-activated protein kinase 5
chr11_-_76027726 0.10 ENSMUST00000021207.6
family with sequence similarity 101, member B
chr7_-_119479249 0.10 ENSMUST00000033263.4
uromodulin
chr17_+_12378603 0.10 ENSMUST00000014578.5
plasminogen
chr11_+_110968056 0.10 ENSMUST00000125692.1
potassium inwardly-rectifying channel, subfamily J, member 16
chr11_+_11487671 0.10 ENSMUST00000020410.4
RIKEN cDNA 4930415F15 gene
chr6_-_147243794 0.09 ENSMUST00000153786.1
predicted gene 15767
chr13_-_112580662 0.09 ENSMUST00000051756.6
interleukin 31 receptor A
chr10_+_63061582 0.08 ENSMUST00000020266.8
ENSMUST00000178684.1
phenazine biosynthesis-like protein domain containing 1
chr9_+_108795971 0.08 ENSMUST00000085018.4
inositol hexaphosphate kinase 2
chr11_+_116848901 0.08 ENSMUST00000143184.1
methyltransferase like 23

Network of associatons between targets according to the STRING database.

First level regulatory network of Hnf1b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 6.2 GO:0033189 response to vitamin A(GO:0033189)
0.9 2.8 GO:0010716 negative regulation of extracellular matrix disassembly(GO:0010716)
0.7 2.6 GO:0015827 aromatic amino acid transport(GO:0015801) tryptophan transport(GO:0015827)
0.5 2.0 GO:0016332 establishment or maintenance of polarity of embryonic epithelium(GO:0016332)
0.5 4.3 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.4 1.3 GO:1903903 regulation of establishment of T cell polarity(GO:1903903)
0.4 1.6 GO:0035482 gastric motility(GO:0035482)
0.4 1.2 GO:0052422 modulation by symbiont of host molecular function(GO:0052055) modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
0.4 2.2 GO:0038161 prolactin signaling pathway(GO:0038161)
0.4 1.1 GO:0034971 histone H3-R17 methylation(GO:0034971)
0.4 4.4 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.3 1.2 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.3 1.0 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.2 2.2 GO:0071231 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713) cellular response to folic acid(GO:0071231)
0.2 1.0 GO:0009436 glyoxylate catabolic process(GO:0009436)
0.2 2.1 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.2 1.1 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.2 1.0 GO:0007223 Wnt signaling pathway, calcium modulating pathway(GO:0007223)
0.2 1.0 GO:0000103 sulfate assimilation(GO:0000103)
0.2 0.9 GO:0031437 regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.2 2.0 GO:0002826 negative regulation of T-helper 1 type immune response(GO:0002826)
0.2 1.6 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.2 0.8 GO:0015788 UDP-N-acetylglucosamine transport(GO:0015788)
0.2 0.5 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
0.1 0.5 GO:0050787 detoxification of mercury ion(GO:0050787)
0.1 0.9 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.1 0.5 GO:0032385 positive regulation of intracellular lipid transport(GO:0032379) positive regulation of intracellular sterol transport(GO:0032382) positive regulation of intracellular cholesterol transport(GO:0032385) lipid hydroperoxide transport(GO:1901373)
0.1 0.9 GO:1904220 regulation of serine C-palmitoyltransferase activity(GO:1904220)
0.1 0.6 GO:0019532 oxalate transport(GO:0019532)
0.1 0.5 GO:1902477 defense response to bacterium, incompatible interaction(GO:0009816) regulation of defense response to bacterium, incompatible interaction(GO:1902477)
0.1 0.3 GO:0002727 natural killer cell cytokine production(GO:0002370) regulation of natural killer cell cytokine production(GO:0002727)
0.1 0.5 GO:0042536 negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.1 1.5 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.1 0.6 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.1 0.3 GO:0071718 sodium-independent icosanoid transport(GO:0071718)
0.1 0.3 GO:0015886 heme transport(GO:0015886)
0.1 0.2 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.1 0.4 GO:0034436 glycoprotein transport(GO:0034436)
0.1 0.4 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.1 0.1 GO:1904956 Wnt signaling pathway involved in somitogenesis(GO:0090244) regulation of midbrain dopaminergic neuron differentiation(GO:1904956)
0.1 0.6 GO:0042421 norepinephrine biosynthetic process(GO:0042421)
0.1 0.2 GO:0061296 regulation of pronephros size(GO:0035565) mesonephros morphogenesis(GO:0061206) mesonephric nephron development(GO:0061215) mesonephric nephron morphogenesis(GO:0061228) mesenchymal stem cell maintenance involved in mesonephric nephron morphogenesis(GO:0061235) regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061295) negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061296) mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:1901146)
0.1 0.7 GO:0015868 purine ribonucleotide transport(GO:0015868)
0.1 7.5 GO:0060349 bone morphogenesis(GO:0060349)
0.1 0.1 GO:0072236 metanephric loop of Henle development(GO:0072236)
0.1 1.8 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.2 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.1 GO:0009812 flavonoid metabolic process(GO:0009812)
0.0 0.2 GO:0015851 nucleobase transport(GO:0015851) pyrimidine nucleobase transport(GO:0015855)
0.0 0.8 GO:0010225 response to UV-C(GO:0010225)
0.0 0.2 GO:1901525 negative regulation of macromitophagy(GO:1901525)
0.0 0.7 GO:0036159 inner dynein arm assembly(GO:0036159)
0.0 0.5 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0 1.9 GO:0010824 regulation of centrosome duplication(GO:0010824)
0.0 0.4 GO:0002349 histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
0.0 2.5 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.3 GO:0009235 cobalamin metabolic process(GO:0009235)
0.0 0.2 GO:0033684 positive regulation of gonadotropin secretion(GO:0032278) regulation of luteinizing hormone secretion(GO:0033684)
0.0 0.1 GO:0006548 histidine catabolic process(GO:0006548)
0.0 0.6 GO:0032933 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 0.1 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.0 0.6 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.0 0.2 GO:0001830 trophectodermal cell fate commitment(GO:0001830)
0.0 0.1 GO:0035905 ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910) negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000820)
0.0 0.1 GO:0044830 modulation by host of viral RNA genome replication(GO:0044830)
0.0 0.4 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 1.6 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.2 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 1.3 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 0.2 GO:1904706 negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.0 1.0 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.9 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 0.9 GO:0051180 vitamin transport(GO:0051180)
0.0 0.2 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 0.4 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0 0.1 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.0 0.2 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.0 0.1 GO:0031133 regulation of axon diameter(GO:0031133)
0.0 0.1 GO:0002857 stimulatory C-type lectin receptor signaling pathway(GO:0002223) positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.0 0.1 GO:0006083 acetate metabolic process(GO:0006083)
0.0 0.3 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.2 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 0.3 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 1.3 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.1 GO:0090400 stress-induced premature senescence(GO:0090400)
0.0 0.2 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.5 GO:0015893 drug transport(GO:0015893)
0.0 0.2 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.0 0.2 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.3 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.8 GO:0071438 invadopodium membrane(GO:0071438)
0.3 0.9 GO:0030690 Noc1p-Noc2p complex(GO:0030690)
0.1 0.9 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.1 2.2 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.1 1.3 GO:0031254 uropod(GO:0001931) flotillin complex(GO:0016600) cell trailing edge(GO:0031254)
0.1 2.7 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.1 0.2 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.1 1.2 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 0.7 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 0.7 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 2.0 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.4 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.3 GO:0019815 B cell receptor complex(GO:0019815)
0.0 0.5 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0 0.1 GO:0044218 other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.0 5.6 GO:0005923 bicellular tight junction(GO:0005923)
0.0 0.6 GO:0033655 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.0 0.5 GO:0031143 pseudopodium(GO:0031143)
0.0 0.7 GO:0005922 connexon complex(GO:0005922)
0.0 0.2 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 1.1 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.2 GO:0061689 tricellular tight junction(GO:0061689)
0.0 2.4 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.2 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.8 GO:0031902 late endosome membrane(GO:0031902)
0.0 1.4 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 4.3 GO:0000139 Golgi membrane(GO:0000139)
0.0 1.8 GO:0036064 ciliary basal body(GO:0036064)
0.0 1.3 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.4 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 4.3 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.1 GO:0032156 septin cytoskeleton(GO:0032156)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.9 GO:0008431 vitamin E binding(GO:0008431)
1.1 4.3 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733)
0.7 2.0 GO:0002113 interleukin-33 binding(GO:0002113)
0.4 2.2 GO:0004925 prolactin receptor activity(GO:0004925)
0.4 2.8 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.3 1.6 GO:0004994 somatostatin receptor activity(GO:0004994)
0.3 1.1 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.2 1.0 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.2 0.9 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.2 2.8 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.2 1.2 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.2 1.1 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.2 1.1 GO:0038181 bile acid receptor activity(GO:0038181)
0.2 0.9 GO:0035877 death effector domain binding(GO:0035877)
0.2 2.2 GO:0051870 methotrexate binding(GO:0051870)
0.2 2.0 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.2 0.9 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.1 1.2 GO:0001849 complement component C1q binding(GO:0001849)
0.1 0.4 GO:0004346 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.1 0.5 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.1 0.4 GO:0034437 glycoprotein transporter activity(GO:0034437)
0.1 4.3 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 0.5 GO:0050632 propanoyl-CoA C-acyltransferase activity(GO:0033814) propionyl-CoA C2-trimethyltridecanoyltransferase activity(GO:0050632) phosphatidylethanolamine transporter activity(GO:1904121)
0.1 0.6 GO:0008422 beta-glucosidase activity(GO:0008422)
0.1 2.2 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.4 GO:1990460 leptin receptor binding(GO:1990460)
0.1 0.3 GO:0042284 sphingolipid delta-4 desaturase activity(GO:0042284)
0.1 0.3 GO:0015232 heme transporter activity(GO:0015232)
0.1 0.3 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.1 0.5 GO:0004556 alpha-amylase activity(GO:0004556)
0.1 1.0 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 1.4 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.1 7.6 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 7.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 0.4 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.1 0.2 GO:0033695 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0 1.8 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.6 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.7 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0 0.6 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.0 0.7 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.1 GO:0035939 microsatellite binding(GO:0035939)
0.0 0.2 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.0 0.8 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.2 GO:0005350 purine nucleobase transmembrane transporter activity(GO:0005345) pyrimidine nucleobase transmembrane transporter activity(GO:0005350) nucleobase transmembrane transporter activity(GO:0015205)
0.0 0.3 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.8 GO:0005402 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.0 0.1 GO:0019807 aspartoacylase activity(GO:0019807)
0.0 0.9 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 5.4 GO:0030165 PDZ domain binding(GO:0030165)
0.0 1.0 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.8 GO:0097602 cullin family protein binding(GO:0097602)
0.0 1.3 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 1.4 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.4 GO:0001848 complement binding(GO:0001848)
0.0 0.3 GO:0004955 prostaglandin receptor activity(GO:0004955)
0.0 0.5 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.4 GO:0005549 odorant binding(GO:0005549)
0.0 0.1 GO:0048019 receptor antagonist activity(GO:0048019)
0.0 0.1 GO:0000832 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.0 0.0 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.0 1.2 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.2 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.3 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.3 GO:0000146 microfilament motor activity(GO:0000146)
0.0 0.3 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.2 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 15.4 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 2.2 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.2 PID CONE PATHWAY Visual signal transduction: Cones
0.0 1.2 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 2.8 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 2.2 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.9 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 1.1 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.9 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 1.1 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 1.2 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.2 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.4 PID REELIN PATHWAY Reelin signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 7.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.2 2.3 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.1 2.8 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1 2.2 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.1 4.3 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.1 0.6 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.1 1.1 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 0.9 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 2.2 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 1.3 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.7 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 1.0 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.4 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 1.3 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.4 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.5 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0 1.0 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.2 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 1.2 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.7 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.6 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.5 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.1 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 3.1 REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS Genes involved in Class A/1 (Rhodopsin-like receptors)