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12D miR HR13_24

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Results for Nr1h2

Z-value: 1.17

Motif logo

Transcription factors associated with Nr1h2

Gene Symbol Gene ID Gene Info
ENSMUSG00000060601.6 nuclear receptor subfamily 1, group H, member 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nr1h2mm10_v2_chr7_-_44553901_44553955-0.643.6e-02Click!

Activity profile of Nr1h2 motif

Sorted Z-values of Nr1h2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_46238464 2.39 ENSMUST00000154292.2
ENSMUST00000078680.6
ENSMUST00000177212.1
ENSMUST00000009667.5
Usher syndrome 1C
chr4_+_40472180 2.22 ENSMUST00000049655.2
transmembrane protein 215
chr11_+_115834314 1.99 ENSMUST00000173289.1
ENSMUST00000137900.1
lethal giant larvae homolog 2 (Drosophila)
chr8_-_106136792 1.58 ENSMUST00000146940.1
epithelial splicing regulatory protein 2
chr10_-_68541842 1.52 ENSMUST00000020103.2
RIKEN cDNA 1700040L02 gene
chr5_-_100159261 1.52 ENSMUST00000139520.1
transmembrane protein 150C
chr1_+_58711488 1.40 ENSMUST00000097722.2
ENSMUST00000114313.1
CASP8 and FADD-like apoptosis regulator
chr11_-_60210410 1.33 ENSMUST00000144942.1
sterol regulatory element binding transcription factor 1
chr8_-_106136890 1.33 ENSMUST00000115979.2
epithelial splicing regulatory protein 2
chr7_+_112953955 1.30 ENSMUST00000182858.1
Ras association (RalGDS/AF-6) domain family (N-terminal) member 10
chr10_-_60938123 1.22 ENSMUST00000036304.3
polymorphic derived intron containing
chr14_-_72602945 1.16 ENSMUST00000162825.1
fibronectin type III domain containing 3A
chr12_-_87233556 1.10 ENSMUST00000021423.7
NADP+ dependent oxidoreductase domain containing 1
chr2_+_155382186 1.07 ENSMUST00000134218.1
transformation related protein 53 inducible nuclear protein 2
chr2_+_131210501 1.06 ENSMUST00000110206.1
adaptor-related protein 5 complex, sigma 1 subunit
chr4_-_53159885 1.03 ENSMUST00000030010.3
ATP-binding cassette, sub-family A (ABC1), member 1
chr2_-_65238573 0.96 ENSMUST00000090896.3
ENSMUST00000155082.1
Cobl-like 1
chr2_-_65238625 0.95 ENSMUST00000112429.2
ENSMUST00000102726.1
ENSMUST00000112430.1
Cobl-like 1
chr17_-_56218881 0.93 ENSMUST00000038794.4
dipeptidylpeptidase 9
chr3_-_59635733 0.93 ENSMUST00000177879.1
predicted gene 5709
chr3_+_3508024 0.91 ENSMUST00000108393.1
ENSMUST00000017832.8
hepatocyte nuclear factor 4, gamma
chr1_-_131276914 0.89 ENSMUST00000161764.1
inhibitor of kappaB kinase epsilon
chr2_-_104849465 0.87 ENSMUST00000126824.1
proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
chr1_-_164458345 0.84 ENSMUST00000027863.7
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr19_+_42247544 0.83 ENSMUST00000122375.1
golgi autoantigen, golgin subfamily a, 7B
chr5_+_117357274 0.83 ENSMUST00000031309.9
WD repeat and SOCS box-containing 2
chr4_-_129440800 0.82 ENSMUST00000053042.5
ENSMUST00000106046.1
zinc finger and BTB domain containing 8b
chr5_+_123015010 0.80 ENSMUST00000121652.1
ENSMUST00000051016.4
ORAI calcium release-activated calcium modulator 1
chr9_+_37208291 0.80 ENSMUST00000034632.8
transmembrane protein 218
chr11_+_29718563 0.80 ENSMUST00000060992.5
reticulon 4
chr10_-_109823585 0.80 ENSMUST00000161582.1
neuron navigator 3
chr19_-_5845471 0.79 ENSMUST00000174287.1
ENSMUST00000173672.1
nuclear paraspeckle assembly transcript 1 (non-protein coding)
chr2_+_155381808 0.75 ENSMUST00000043237.7
ENSMUST00000174685.1
transformation related protein 53 inducible nuclear protein 2
chr3_+_146597077 0.75 ENSMUST00000029837.7
ENSMUST00000121133.1
urate oxidase
chr5_+_117363513 0.74 ENSMUST00000111959.1
WD repeat and SOCS box-containing 2
chr1_+_131599239 0.73 ENSMUST00000027690.6
arginine vasopressin receptor 1B
chr5_+_130219706 0.71 ENSMUST00000065329.6
transmembrane protein 248
chr15_+_65787023 0.71 ENSMUST00000015146.9
ENSMUST00000173858.1
ENSMUST00000172756.1
ENSMUST00000174856.1
EFR3 homolog A (S. cerevisiae)
chr6_+_124663027 0.69 ENSMUST00000004381.7
lysophosphatidylcholine acyltransferase 3
chr11_-_103697898 0.69 ENSMUST00000021329.7
golgi SNAP receptor complex member 2
chr10_-_53638269 0.69 ENSMUST00000164393.1
family with sequence similarity 184, member A
chr17_-_83846769 0.68 ENSMUST00000000687.7
3-hydroxyanthranilate 3,4-dioxygenase
chr16_+_96205719 0.66 ENSMUST00000129904.1
SH3-binding domain glutamic acid-rich protein
chr19_-_46672883 0.64 ENSMUST00000026012.7
cytochrome P450, family 17, subfamily a, polypeptide 1
chr11_-_30025915 0.62 ENSMUST00000058902.5
echinoderm microtubule associated protein like 6
chr3_+_90514435 0.61 ENSMUST00000048138.6
ENSMUST00000181271.1
S100 calcium binding protein A13
chr4_-_42168603 0.59 ENSMUST00000098121.3
predicted gene 13305
chr5_-_122779278 0.57 ENSMUST00000111668.3
calcium/calmodulin-dependent protein kinase kinase 2, beta
chr12_-_110978981 0.57 ENSMUST00000135131.1
ENSMUST00000043459.6
ENSMUST00000128353.1
ankyrin repeat domain 9
chr3_-_95241598 0.57 ENSMUST00000090815.5
ENSMUST00000107197.1
predicted gene 128
chr16_+_13940630 0.57 ENSMUST00000141971.1
ENSMUST00000124947.1
ENSMUST00000023360.7
ENSMUST00000143697.1
Mpv17 transgene, kidney disease mutant-like
chr7_+_125318334 0.55 ENSMUST00000060220.1
RIKEN cDNA 4930533L02 gene
chr4_+_120532219 0.55 ENSMUST00000062990.3
schlafen like 1
chrX_-_53608979 0.55 ENSMUST00000123034.1
predicted gene 14597
chr4_-_119422355 0.51 ENSMUST00000106316.1
ENSMUST00000030385.6
phosphopantothenoylcysteine synthetase
chr2_-_113829069 0.51 ENSMUST00000024005.7
secretogranin V
chr6_-_134632388 0.50 ENSMUST00000047443.3
MANSC domain containing 1
chr11_-_98400453 0.49 ENSMUST00000090827.5
post-GPI attachment to proteins 3
chr5_+_115466234 0.49 ENSMUST00000145785.1
ENSMUST00000031495.4
ENSMUST00000112071.1
ENSMUST00000125568.1
phospholipase A2, group IB, pancreas
chr3_+_145292472 0.48 ENSMUST00000029848.4
ENSMUST00000139001.1
collagen, type XXIV, alpha 1
chr10_+_18845071 0.48 ENSMUST00000019998.7
PERP, TP53 apoptosis effector
chr15_-_89425795 0.46 ENSMUST00000168376.1
carnitine palmitoyltransferase 1b, muscle
chr7_+_81523531 0.46 ENSMUST00000181903.1
RIKEN cDNA 2900076A07 gene
chr12_-_110978943 0.46 ENSMUST00000142012.1
ankyrin repeat domain 9
chr15_+_78877172 0.46 ENSMUST00000041587.7
golgi associated, gamma adaptin ear containing, ARF binding protein 1
chr2_+_131210363 0.46 ENSMUST00000110210.1
ENSMUST00000089506.5
ENSMUST00000110208.1
adaptor-related protein 5 complex, sigma 1 subunit
chr10_+_21993890 0.46 ENSMUST00000092673.4
serum/glucocorticoid regulated kinase 1
chrX_-_102644210 0.44 ENSMUST00000052012.7
ENSMUST00000043596.5
ENSMUST00000119229.1
ENSMUST00000122022.1
ENSMUST00000120270.1
ENSMUST00000113611.2
phosphorylase kinase alpha 1
chr12_+_108792946 0.44 ENSMUST00000021692.7
YY1 transcription factor
chr6_+_125320633 0.43 ENSMUST00000176655.1
ENSMUST00000176110.1
sodium channel, nonvoltage-gated 1 alpha
chr8_-_70632419 0.43 ENSMUST00000110103.1
growth differentiation factor 15
chr2_-_26604267 0.43 ENSMUST00000028286.5
1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta)
chr4_+_43641262 0.41 ENSMUST00000123351.1
ENSMUST00000128549.1
natriuretic peptide receptor 2
chr4_-_63154130 0.41 ENSMUST00000030041.4
alpha 1 microglobulin/bikunin
chr6_+_90462562 0.40 ENSMUST00000032174.5
Kruppel-like factor 15
chr6_+_88902251 0.40 ENSMUST00000055022.8
transmembrane protein, adipocyte asscociated 1
chr15_-_89410230 0.38 ENSMUST00000109314.2
synaptonemal complex central element protein 3
chr4_+_123859651 0.38 ENSMUST00000097896.2
Riken cDNA 4933427I04 gene
chr13_-_12461432 0.38 ENSMUST00000143693.1
ENSMUST00000144283.1
ENSMUST00000099820.3
ENSMUST00000135166.1
lectin, galactose binding, soluble 8
chr2_+_61593077 0.37 ENSMUST00000112495.1
ENSMUST00000112501.2
TRAF family member-associated Nf-kappa B activator
chr1_+_31176404 0.37 ENSMUST00000062560.7
lengsin, lens protein with glutamine synthetase domain
chr15_+_85832301 0.36 ENSMUST00000146088.1
tetratricopeptide repeat domain 38
chr2_+_61593125 0.35 ENSMUST00000112494.1
TRAF family member-associated Nf-kappa B activator
chr3_-_116423930 0.35 ENSMUST00000106491.2
CDC14 cell division cycle 14A
chr11_-_101119889 0.35 ENSMUST00000017946.5
family with sequence similarity 134, member C
chr3_+_89245952 0.34 ENSMUST00000040888.5
keratinocyte associated protein 2
chr14_-_20730327 0.33 ENSMUST00000047490.5
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
chr2_+_131491764 0.33 ENSMUST00000028806.5
ENSMUST00000110179.2
ENSMUST00000110189.2
ENSMUST00000110182.2
ENSMUST00000110183.2
ENSMUST00000110186.2
ENSMUST00000110188.1
spermine oxidase
chr17_-_56716788 0.33 ENSMUST00000067931.5
vimentin-type intermediate filament associated coiled-coil protein
chrX_-_136085206 0.33 ENSMUST00000138878.1
ENSMUST00000080929.6
nuclear RNA export factor 3
chr6_+_54429603 0.33 ENSMUST00000132855.1
ENSMUST00000126637.1
WAS/WASL interacting protein family, member 3
chr3_-_116424007 0.32 ENSMUST00000090464.4
CDC14 cell division cycle 14A
chr6_+_142756680 0.30 ENSMUST00000032419.8
cytidine monophospho-N-acetylneuraminic acid synthetase
chr3_+_89246397 0.30 ENSMUST00000168900.1
keratinocyte associated protein 2
chr5_+_103754154 0.29 ENSMUST00000054979.3
AF4/FMR2 family, member 1
chr18_+_37333853 0.29 ENSMUST00000061717.2
protocadherin beta 6
chr2_+_153918391 0.29 ENSMUST00000109760.1
BPI fold containing family B, member 3
chr5_-_17849783 0.28 ENSMUST00000170051.1
ENSMUST00000165232.1
CD36 antigen
chr5_-_124327883 0.28 ENSMUST00000031344.6
M-phase phosphoprotein 9
chr9_-_63399216 0.28 ENSMUST00000168665.1
RIKEN cDNA 2300009A05 gene
chr16_+_17894197 0.27 ENSMUST00000046937.2
testis-specific serine kinase 1
chr5_+_124328083 0.27 ENSMUST00000111477.1
ENSMUST00000077376.2
RIKEN cDNA 2810006K23 gene
chr9_+_77941274 0.27 ENSMUST00000134072.1
ELOVL family member 5, elongation of long chain fatty acids (yeast)
chr17_+_24804312 0.26 ENSMUST00000024972.5
meiosis specific with OB domains
chr12_-_111813834 0.26 ENSMUST00000021715.5
X-ray repair complementing defective repair in Chinese hamster cells 3
chr2_+_156420837 0.25 ENSMUST00000103137.3
erythrocyte protein band 4.1-like 1
chr11_-_102556122 0.25 ENSMUST00000143842.1
G patch domain containing 8
chr2_+_156421048 0.24 ENSMUST00000109574.1
erythrocyte protein band 4.1-like 1
chr2_+_110721340 0.23 ENSMUST00000111016.2
mucin 15
chr11_-_101119814 0.23 ENSMUST00000107295.3
family with sequence similarity 134, member C
chr17_+_49428359 0.23 ENSMUST00000165390.2
ENSMUST00000024797.9
ENSMUST00000173033.1
molybdenum cofactor synthesis 1
chr2_-_164911586 0.22 ENSMUST00000041361.7
zinc finger protein 335
chr7_-_47528862 0.20 ENSMUST00000172559.1
MAS-related GPR, member A2B
chr10_-_81600857 0.20 ENSMUST00000151858.1
ENSMUST00000142948.1
ENSMUST00000072020.2
transducin-like enhancer of split 6, homolog of Drosophila E(spl)
chr15_+_74714832 0.20 ENSMUST00000023265.3
prostate stem cell antigen
chr3_-_89245829 0.20 ENSMUST00000041022.8
tripartite motif-containing 46
chr14_+_75016027 0.19 ENSMUST00000036072.7
RIKEN cDNA 5031414D18 gene
chr2_+_110721587 0.19 ENSMUST00000111017.2
mucin 15
chr15_+_102990576 0.19 ENSMUST00000001703.6
homeobox C8
chr4_-_118457450 0.18 ENSMUST00000106375.1
ENSMUST00000006556.3
ENSMUST00000168404.1
myeloproliferative leukemia virus oncogene
chr14_+_54632329 0.18 ENSMUST00000173083.1
predicted gene, 20726
chr14_-_50924626 0.18 ENSMUST00000160375.1
ENSMUST00000162177.1
ENSMUST00000159292.1
O-sialoglycoprotein endopeptidase
chr2_-_13793793 0.18 ENSMUST00000003509.8
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6
chr7_+_27862557 0.17 ENSMUST00000053722.8
zinc finger proten 607
chr2_+_110721632 0.16 ENSMUST00000090332.4
mucin 15
chr4_-_36056726 0.16 ENSMUST00000108124.3
leucine rich repeat and Ig domain containing 2
chr17_-_25985641 0.16 ENSMUST00000041641.8
calpain 15
chr14_+_54686171 0.15 ENSMUST00000038539.6
RIKEN cDNA 1700123O20 gene
chr16_+_16870829 0.15 ENSMUST00000131063.1
topoisomerase (DNA) III beta
chr4_-_118457509 0.15 ENSMUST00000102671.3
myeloproliferative leukemia virus oncogene
chr7_-_27446599 0.15 ENSMUST00000011895.7
spectrin beta, non-erythrocytic 4
chr4_+_123917420 0.14 ENSMUST00000030399.6
Ras-related GTP binding C
chr8_-_84237042 0.14 ENSMUST00000039480.5
zinc finger SWIM-type containing 4
chr1_+_78657825 0.14 ENSMUST00000035779.8
acyl-CoA synthetase long-chain family member 3
chr11_+_78245743 0.14 ENSMUST00000002133.8
stromal cell derived factor 2
chr7_-_19770509 0.14 ENSMUST00000003061.7
basal cell adhesion molecule
chr4_+_101507947 0.13 ENSMUST00000149047.1
ENSMUST00000106929.3
DnaJ (Hsp40) homolog, subfamily C, member 6
chr7_-_133776681 0.12 ENSMUST00000130182.1
ENSMUST00000106139.1
DEAH (Asp-Glu-Ala-His) box polypeptide 32
chr2_+_156421083 0.12 ENSMUST00000125153.2
ENSMUST00000103136.1
ENSMUST00000109577.2
erythrocyte protein band 4.1-like 1
chr18_+_59175333 0.12 ENSMUST00000080721.4
chondroitin sulfate synthase 3
chr11_+_55098104 0.12 ENSMUST00000000608.7
GM2 ganglioside activator protein
chr13_+_23695791 0.11 ENSMUST00000041052.2
histone cluster 1, H1t
chr11_-_83530505 0.10 ENSMUST00000035938.2
chemokine (C-C motif) ligand 5
chr8_-_36249292 0.10 ENSMUST00000065297.5
LON peptidase N-terminal domain and ring finger 1
chr9_+_65361049 0.09 ENSMUST00000147185.1
predicted gene 514
chr4_+_101507855 0.09 ENSMUST00000038207.5
DnaJ (Hsp40) homolog, subfamily C, member 6
chr13_+_102693596 0.09 ENSMUST00000172138.1
CD180 antigen
chr1_+_6214627 0.08 ENSMUST00000027040.6
RB1-inducible coiled-coil 1
chr3_-_138186700 0.08 ENSMUST00000012186.4
RIKEN cDNA 4930579F01 gene
chr7_+_67647405 0.07 ENSMUST00000032774.8
ENSMUST00000107471.1
tetratricopeptide repeat domain 23
chr9_+_110844497 0.07 ENSMUST00000176403.1
protease, serine, 46
chr4_-_46389391 0.07 ENSMUST00000086563.4
ENSMUST00000030015.5
RIKEN cDNA 5830415F09 gene
chr17_-_79715034 0.07 ENSMUST00000024894.1
cytochrome P450, family 1, subfamily b, polypeptide 1
chr4_-_141538434 0.06 ENSMUST00000078886.3
SPEN homolog, transcriptional regulator (Drosophila)
chr5_-_120588613 0.06 ENSMUST00000046426.8
two pore channel 1
chr4_-_141538562 0.06 ENSMUST00000105786.2
SPEN homolog, transcriptional regulator (Drosophila)
chr12_-_21286097 0.06 ENSMUST00000173729.1
integrin beta 1 binding protein 1
chr11_+_58963790 0.05 ENSMUST00000075141.6
tripartite motif-containing 17
chr1_+_33719863 0.05 ENSMUST00000088287.3
RAB23, member RAS oncogene family
chr2_+_122738495 0.05 ENSMUST00000005954.8
biogenesis of organelles complex-1, subunit 6, pallidin
chr7_+_81523555 0.05 ENSMUST00000180385.1
ENSMUST00000180879.1
ENSMUST00000181164.1
ENSMUST00000181264.1
RIKEN cDNA 2900076A07 gene
chr10_-_67548944 0.05 ENSMUST00000075686.4
2-aminoethanethiol (cysteamine) dioxygenase
chr18_+_89197421 0.03 ENSMUST00000037142.5
CD226 antigen
chr8_+_4238733 0.03 ENSMUST00000110998.2
ENSMUST00000062686.4
mitogen-activated protein kinase kinase 7
chr5_+_146525801 0.03 ENSMUST00000110596.1
predicted gene 3404
chr7_-_25718976 0.02 ENSMUST00000002683.2
coiled-coil domain containing 97
chr5_+_146502428 0.02 ENSMUST00000110598.1
RIKEN cDNA 4930449I24 gene
chr5_+_146491363 0.02 ENSMUST00000110611.3
predicted gene 6370
chr12_+_21286297 0.01 ENSMUST00000067284.8
cleavage and polyadenylation specificity factor 3
chr10_+_77893413 0.01 ENSMUST00000178996.1
RIKEN cDNA 1700009J07 gene
chr12_-_87147883 0.01 ENSMUST00000037788.4
protein-O-mannosyltransferase 2
chr16_+_87784075 0.01 ENSMUST00000069809.4
RIKEN cDNA 2810407A14 gene
chr8_+_4238815 0.01 ENSMUST00000003027.7
ENSMUST00000110999.1
mitogen-activated protein kinase kinase 7
chr19_+_46707443 0.01 ENSMUST00000003655.7
arsenic (+3 oxidation state) methyltransferase
chr5_-_136565432 0.00 ENSMUST00000176172.1
cut-like homeobox 1

Network of associatons between targets according to the STRING database.

First level regulatory network of Nr1h2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.0 GO:0016332 establishment or maintenance of polarity of embryonic epithelium(GO:0016332)
0.5 2.4 GO:1904970 brush border assembly(GO:1904970)
0.4 1.4 GO:0014732 skeletal muscle atrophy(GO:0014732) negative regulation of myoblast fusion(GO:1901740) regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.3 0.8 GO:1903279 regulation of calcium:sodium antiporter activity(GO:1903279)
0.3 1.0 GO:0055099 response to high density lipoprotein particle(GO:0055099) platelet dense granule organization(GO:0060155)
0.2 0.7 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.2 0.7 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.2 1.1 GO:0006561 proline biosynthetic process(GO:0006561)
0.1 1.3 GO:0003062 regulation of heart rate by chemical signal(GO:0003062)
0.1 0.4 GO:0071707 immunoglobulin heavy chain V-D-J recombination(GO:0071707)
0.1 0.6 GO:0061762 CAMKK-AMPK signaling cascade(GO:0061762)
0.1 0.8 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.1 0.4 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.1 0.3 GO:0035702 monocyte homeostasis(GO:0035702)
0.1 0.6 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.1 0.3 GO:0070543 response to linoleic acid(GO:0070543)
0.1 0.6 GO:0050703 interleukin-1 alpha secretion(GO:0050703)
0.1 0.7 GO:0046874 quinolinate metabolic process(GO:0046874)
0.1 0.3 GO:0046381 CMP-N-acetylneuraminate metabolic process(GO:0046381)
0.1 0.8 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.1 1.9 GO:0051639 actin filament network formation(GO:0051639)
0.1 2.9 GO:0060445 branching involved in salivary gland morphogenesis(GO:0060445)
0.1 0.3 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.1 0.7 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.1 0.4 GO:0002317 plasma cell differentiation(GO:0002317)
0.1 0.7 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.1 GO:0090004 positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.0 0.7 GO:0046415 urate metabolic process(GO:0046415)
0.0 0.2 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 0.3 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.0 0.4 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168) negative regulation of oocyte maturation(GO:1900194)
0.0 0.8 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.6 GO:0042448 progesterone metabolic process(GO:0042448)
0.0 0.4 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.2 GO:0019720 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.0 1.2 GO:0060009 Sertoli cell development(GO:0060009)
0.0 0.5 GO:0002934 desmosome organization(GO:0002934)
0.0 0.2 GO:0072318 clathrin coat disassembly(GO:0072318)
0.0 0.8 GO:0030575 nuclear body organization(GO:0030575)
0.0 0.5 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.4 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.4 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.0 0.3 GO:0007144 female meiosis I(GO:0007144)
0.0 0.9 GO:0010884 positive regulation of lipid storage(GO:0010884)
0.0 0.5 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.6 GO:0018195 peptidyl-arginine modification(GO:0018195)
0.0 0.3 GO:0002002 regulation of angiotensin levels in blood(GO:0002002)
0.0 0.5 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.1 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634) positive regulation of natural killer cell chemotaxis(GO:2000503)
0.0 0.3 GO:0034625 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.1 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.0 0.4 GO:0072311 renal filtration cell differentiation(GO:0061318) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0 0.4 GO:1901739 regulation of myoblast fusion(GO:1901739) positive regulation of myoblast fusion(GO:1901741)
0.0 1.9 GO:0000045 autophagosome assembly(GO:0000045)
0.0 1.3 GO:0030317 sperm motility(GO:0030317)
0.0 0.1 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.3 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.1 GO:0009313 ganglioside catabolic process(GO:0006689) oligosaccharide catabolic process(GO:0009313)
0.0 0.2 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
0.0 0.2 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 1.5 GO:0000724 double-strand break repair via homologous recombination(GO:0000724) recombinational repair(GO:0000725)
0.0 0.4 GO:0050891 multicellular organismal water homeostasis(GO:0050891)
0.0 0.2 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.1 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 0.4 GO:0035825 reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.0 0.5 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.5 GO:0009395 phospholipid catabolic process(GO:0009395)
0.0 0.0 GO:0002727 natural killer cell cytokine production(GO:0002370) regulation of natural killer cell cytokine production(GO:0002727)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.4 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.1 0.3 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.1 0.8 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 0.8 GO:0042382 paraspeckles(GO:0042382)
0.1 0.3 GO:0097447 dendritic tree(GO:0097447)
0.1 0.8 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.1 0.4 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.1 0.3 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.7 GO:0001533 cornified envelope(GO:0001533)
0.0 0.6 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.3 GO:0045098 type III intermediate filament(GO:0045098)
0.0 2.4 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.2 GO:1990769 proximal neuron projection(GO:1990769)
0.0 0.2 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 2.0 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 0.7 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.8 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.4 GO:0031011 Ino80 complex(GO:0031011)
0.0 0.1 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.1 GO:0008091 spectrin(GO:0008091)
0.0 1.7 GO:0005776 autophagosome(GO:0005776)
0.0 0.5 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.4 GO:0034706 sodium channel complex(GO:0034706)
0.0 0.4 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.1 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.4 GO:0032029 myosin tail binding(GO:0032029)
0.3 1.0 GO:0090556 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.3 1.1 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.3 1.3 GO:0032810 sterol response element binding(GO:0032810)
0.2 0.7 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.2 0.9 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704) IkappaB kinase activity(GO:0008384) K48-linked polyubiquitin binding(GO:0036435)
0.2 1.4 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1 0.4 GO:0004356 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211)
0.1 0.7 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.1 0.3 GO:0052901 polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901)
0.1 0.7 GO:0005000 vasopressin receptor activity(GO:0005000)
0.1 0.3 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.1 0.8 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors(GO:0016661)
0.1 0.5 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.1 0.8 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.1 0.4 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.1 0.6 GO:0050786 RAGE receptor binding(GO:0050786)
0.1 0.3 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.1 0.4 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.1 0.8 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 0.5 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.1 0.2 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.1 0.5 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 0.6 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 1.9 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.3 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.6 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.0 0.5 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.7 GO:0019825 oxygen binding(GO:0019825)
0.0 0.1 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0 0.4 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.3 GO:0000150 recombinase activity(GO:0000150)
0.0 0.1 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.0 0.3 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.0 0.8 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.3 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.0 0.4 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 0.4 GO:0019865 immunoglobulin binding(GO:0019865)
0.0 0.1 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.1 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.3 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.3 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.9 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 0.6 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.5 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.0 0.1 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 1.8 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.7 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.7 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.2 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.0 2.0 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.9 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 1.3 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.7 PID ARF 3PATHWAY Arf1 pathway
0.0 1.0 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.9 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.8 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 1.1 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.8 PID P75 NTR PATHWAY p75(NTR)-mediated signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 0.6 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.1 0.8 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 1.6 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.1 1.2 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 1.0 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 1.3 REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION Genes involved in RORA Activates Circadian Expression
0.0 0.7 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.5 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.7 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.6 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.9 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.8 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.4 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.5 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.4 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.7 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.1 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.3 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds