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12D miR HR13_24

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Results for Sox1

Z-value: 0.74

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Transcription factors associated with Sox1

Gene Symbol Gene ID Gene Info
ENSMUSG00000096014.1 SRY (sex determining region Y)-box 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Sox1mm10_v2_chr8_+_12395287_12395295-0.586.1e-02Click!

Activity profile of Sox1 motif

Sorted Z-values of Sox1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_127890918 3.97 ENSMUST00000121394.1
protease, serine, 53
chrX_+_164162167 1.47 ENSMUST00000131543.1
angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
chr8_+_83165348 1.23 ENSMUST00000034145.4
TBC1 domain family, member 9
chr17_+_34263209 0.98 ENSMUST00000040828.5
histocompatibility 2, class II antigen A, beta 1
chr17_+_34969912 0.79 ENSMUST00000173680.1
predicted gene 20481
chr9_+_44326804 0.76 ENSMUST00000054708.3
dolichyl-phosphate (UDP-N-acetylglucosamine) acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)
chr13_+_42301270 0.70 ENSMUST00000021796.7
endothelin 1
chr6_+_37530173 0.66 ENSMUST00000040987.7
aldo-keto reductase family 1, member D1
chr8_+_13159135 0.65 ENSMUST00000033824.6
lysosomal-associated membrane protein 1
chr17_-_34287770 0.63 ENSMUST00000174751.1
ENSMUST00000040655.6
histocompatibility 2, class II antigen A, alpha
chr9_-_108305941 0.62 ENSMUST00000044725.7
T cell leukemia translocation altered gene
chr19_+_3972322 0.59 ENSMUST00000143380.1
aldehyde dehydrogenase 3 family, member B2
chr1_+_109983737 0.52 ENSMUST00000172005.1
cadherin 7, type 2
chr7_+_80343091 0.47 ENSMUST00000032747.5
HD domain containing 3
chr5_-_109691041 0.37 ENSMUST00000092720.3
RIKEN cDNA 5430403G16 gene
chrX_+_74297097 0.36 ENSMUST00000019231.5
ENSMUST00000147900.1
ENSMUST00000147275.1
ENSMUST00000114171.3
ATPase, H+ transporting, lysosomal accessory protein 1
chr2_+_34406845 0.35 ENSMUST00000124443.1
ENSMUST00000113124.1
mitogen-activated protein kinase associated protein 1
chr1_-_195131536 0.30 ENSMUST00000075451.6
complement component (3b/4b) receptor 1-like
chr19_-_8218832 0.30 ENSMUST00000113298.2
solute carrier family 22. member 29
chr18_+_37496997 0.30 ENSMUST00000059571.5
protocadherin beta 19
chr2_+_84798828 0.27 ENSMUST00000102642.2
ENSMUST00000150325.1
ubiquitin-conjugating enzyme E2L 6
chr15_-_74997634 0.27 ENSMUST00000023248.6
lymphocyte antigen 6 complex, locus A
chr17_+_47737030 0.26 ENSMUST00000086932.3
transcription factor EB
chr15_-_75048837 0.25 ENSMUST00000179762.1
ENSMUST00000065408.9
lymphocyte antigen 6 complex, locus C1
chr11_-_68853119 0.23 ENSMUST00000018880.7
nuclear distribution gene E-like homolog 1 (A. nidulans)
chr11_-_68853019 0.22 ENSMUST00000108672.1
nuclear distribution gene E-like homolog 1 (A. nidulans)
chr8_-_88636117 0.22 ENSMUST00000034087.7
sorting nexin 20
chr5_-_129670074 0.20 ENSMUST00000049778.6
zinc finger protein 11
chr7_+_67655414 0.20 ENSMUST00000107470.1
tetratricopeptide repeat domain 23
chr5_+_21186267 0.20 ENSMUST00000036031.8
gamma-secretase activating protein
chr11_+_96133786 0.19 ENSMUST00000167258.1
tubulin tyrosine ligase-like family, member 6
chr7_-_120145286 0.16 ENSMUST00000033207.4
zona pellucida glycoprotein 2
chr7_+_41633531 0.13 ENSMUST00000100275.3
ENSMUST00000131180.1
ENSMUST00000140964.1
ENSMUST00000045720.7
ENSMUST00000098508.2
zinc finger protein 788
chr14_+_65666430 0.11 ENSMUST00000069226.6
scavenger receptor class A, member 5 (putative)
chr4_-_120747248 0.11 ENSMUST00000030376.7
potassium voltage-gated channel, subfamily Q, member 4
chr2_-_84650714 0.10 ENSMUST00000111697.2
ENSMUST00000111670.2
ENSMUST00000111696.1
ENSMUST00000111678.1
ENSMUST00000111690.1
ENSMUST00000111695.1
ENSMUST00000111677.1
ENSMUST00000111698.1
ENSMUST00000099941.2
ENSMUST00000111676.1
ENSMUST00000111694.1
ENSMUST00000111675.1
ENSMUST00000111689.1
ENSMUST00000111687.1
ENSMUST00000111692.1
ENSMUST00000111685.1
ENSMUST00000111686.1
ENSMUST00000111688.1
ENSMUST00000111693.1
ENSMUST00000111684.1
catenin (cadherin associated protein), delta 1
chr2_-_84650760 0.10 ENSMUST00000111691.1
catenin (cadherin associated protein), delta 1
chr10_+_84756055 0.10 ENSMUST00000060397.6
regulatory factor X, 4 (influences HLA class II expression)
chr6_+_117841174 0.09 ENSMUST00000112859.1
ENSMUST00000137224.1
ENSMUST00000164472.1
ENSMUST00000112861.1
ENSMUST00000035638.8
zinc finger protein 637
chr4_-_43483696 0.09 ENSMUST00000030180.6
suppression inducing transmembrane adaptor 1
chr13_-_95478655 0.09 ENSMUST00000022186.3
S100 calcium binding protein, zeta
chr7_-_46919915 0.08 ENSMUST00000143413.1
ENSMUST00000014546.8
tumor susceptibility gene 101
chr4_+_136357423 0.08 ENSMUST00000182167.1
predicted gene, 17388
chr11_+_96134219 0.08 ENSMUST00000107680.1
tubulin tyrosine ligase-like family, member 6
chr6_-_145434925 0.06 ENSMUST00000111708.2
intermediate filament tail domain containing 1
chr17_-_47692466 0.03 ENSMUST00000113300.1
prickle homolog 4 (Drosophila)
chr11_+_104282371 0.02 ENSMUST00000106988.1
ENSMUST00000106989.1
microtubule-associated protein tau

Network of associatons between targets according to the STRING database.

First level regulatory network of Sox1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.5 GO:0015801 aromatic amino acid transport(GO:0015801) tryptophan transport(GO:0015827)
0.3 1.0 GO:0002343 peripheral B cell selection(GO:0002343) B cell affinity maturation(GO:0002344)
0.2 0.6 GO:0043323 positive regulation of natural killer cell degranulation(GO:0043323)
0.2 0.7 GO:0060584 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.1 0.8 GO:0019348 dolichol metabolic process(GO:0019348)
0.1 0.6 GO:0072675 osteoclast fusion(GO:0072675)
0.1 0.4 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.1 0.3 GO:0009816 defense response to bacterium, incompatible interaction(GO:0009816) regulation of defense response to bacterium, incompatible interaction(GO:1902477)
0.1 0.7 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.1 0.4 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.4 GO:0051081 membrane disassembly(GO:0030397) nuclear envelope disassembly(GO:0051081)
0.0 0.6 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.0 0.2 GO:0060690 epithelial cell differentiation involved in salivary gland development(GO:0060690)
0.0 0.3 GO:0045916 negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.0 0.3 GO:0015747 urate transport(GO:0015747)
0.0 0.3 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.3 GO:0051013 microtubule severing(GO:0051013)
0.0 0.1 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.0 0.2 GO:0060468 prevention of polyspermy(GO:0060468)
0.0 0.1 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.0 0.1 GO:0032227 negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.0 1.2 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 0.2 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 0.6 GO:0044194 cytolytic granule(GO:0044194)
0.1 0.7 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.1 0.4 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.0 0.4 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.4 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.2 GO:0005915 zonula adherens(GO:0005915)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.5 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.2 0.8 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.2 0.7 GO:0031708 endothelin B receptor binding(GO:0031708)
0.2 0.7 GO:0035671 steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) enone reductase activity(GO:0035671)
0.1 0.4 GO:0070012 oligopeptidase activity(GO:0070012)
0.1 0.6 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.1 1.0 GO:1990405 protein antigen binding(GO:1990405)
0.1 0.2 GO:0032190 acrosin binding(GO:0032190)
0.0 0.3 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.3 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.3 GO:0070739 protein-glutamic acid ligase activity(GO:0070739)
0.0 4.0 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.6 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.4 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.4 GO:0070300 phosphatidic acid binding(GO:0070300)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.8 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.7 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions