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12D miR HR13_24

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Results for Hoxa5

Z-value: 0.90

Motif logo

Transcription factors associated with Hoxa5

Gene Symbol Gene ID Gene Info
ENSMUSG00000038253.6 homeobox A5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hoxa5mm10_v2_chr6_-_52204415_52204587-0.605.0e-02Click!

Activity profile of Hoxa5 motif

Sorted Z-values of Hoxa5 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr16_+_32756336 1.69 ENSMUST00000135753.1
mucin 4
chr1_-_158814469 1.35 ENSMUST00000161589.2
pappalysin 2
chr2_+_70562854 1.20 ENSMUST00000130998.1
glutamate decarboxylase 1
chr15_-_34356421 1.09 ENSMUST00000179647.1
RIKEN cDNA 9430069I07 gene
chr10_+_128267997 1.09 ENSMUST00000050901.2
apolipoprotein F
chrX_+_164438039 0.94 ENSMUST00000033755.5
ankyrin repeat and SOCS box-containing 11
chr7_-_101864093 0.90 ENSMUST00000106981.1
folate receptor 1 (adult)
chr16_-_32797413 0.72 ENSMUST00000115116.1
ENSMUST00000041123.8
mucin 20
chr7_+_128129536 0.70 ENSMUST00000033053.6
integrin alpha X
chr13_+_72632597 0.66 ENSMUST00000172353.1
Iroquois related homeobox 2 (Drosophila)
chr3_+_106113229 0.65 ENSMUST00000079132.5
ENSMUST00000139086.1
chitinase, acidic
chr16_-_22161450 0.64 ENSMUST00000115379.1
insulin-like growth factor 2 mRNA binding protein 2
chr9_-_62510498 0.64 ENSMUST00000164246.2
coronin, actin binding protein, 2B
chr17_-_31636631 0.63 ENSMUST00000135425.1
ENSMUST00000151718.1
ENSMUST00000155814.1
cystathionine beta-synthase
chrX_+_164436987 0.62 ENSMUST00000036858.4
ankyrin repeat and SOCS box-containing 11
chr17_+_6673610 0.61 ENSMUST00000097430.2
synaptotagmin-like 3
chr11_+_61022560 0.59 ENSMUST00000089184.4
potassium inwardly-rectifying channel, subfamily J, member 12
chr2_+_70563435 0.58 ENSMUST00000123330.1
glutamate decarboxylase 1
chr11_+_16752203 0.57 ENSMUST00000102884.3
ENSMUST00000020329.6
epidermal growth factor receptor
chr4_+_102589687 0.54 ENSMUST00000097949.4
ENSMUST00000106901.1
phosphodiesterase 4B, cAMP specific
chr2_+_58755177 0.54 ENSMUST00000102755.3
uridine phosphorylase 2
chr17_+_21691860 0.51 ENSMUST00000072133.4
predicted gene 10226
chr10_-_75798576 0.49 ENSMUST00000001713.3
glutathione S-transferase, theta 1
chr1_+_174501796 0.48 ENSMUST00000030039.7
formin 2
chr8_-_86580664 0.48 ENSMUST00000131423.1
ENSMUST00000152438.1
ATP-binding cassette, sub-family C (CFTR/MRP), member 12
chr8_+_82863351 0.47 ENSMUST00000078525.5
ring finger protein 150
chr2_+_58754910 0.46 ENSMUST00000059102.6
uridine phosphorylase 2
chr2_-_62412219 0.45 ENSMUST00000047812.7
dipeptidylpeptidase 4
chr12_-_32953772 0.45 ENSMUST00000180391.1
ENSMUST00000181670.1
RIKEN cDNA 4933406C10 gene
chr17_-_35046539 0.45 ENSMUST00000007250.7
mutS homolog 5 (E. coli)
chr4_-_130275542 0.44 ENSMUST00000154846.1
ENSMUST00000105996.1
serine incorporator 2
chr4_+_141239499 0.43 ENSMUST00000141834.2
Rho guanine nucleotide exchange factor (GEF) 19
chr6_+_122990367 0.42 ENSMUST00000079379.2
C-type lectin domain family 4, member a4
chr13_+_23763660 0.41 ENSMUST00000055770.1
histone cluster 1, H1a
chr17_+_37002610 0.41 ENSMUST00000173921.1
ENSMUST00000172580.1
zinc finger protein 57
chr12_+_112678803 0.41 ENSMUST00000174780.1
ENSMUST00000169593.1
ENSMUST00000173942.1
zinc finger and BTB domain containing 42
chr7_-_46099752 0.40 ENSMUST00000180081.1
potassium inwardly rectifying channel, subfamily J, member 11
chr15_-_66560997 0.40 ENSMUST00000048372.5
transmembrane protein 71
chr5_+_122206792 0.39 ENSMUST00000145854.1
hydrogen voltage-gated channel 1
chr11_-_58529984 0.39 ENSMUST00000062869.2
olfactory receptor 330
chr2_+_122765237 0.39 ENSMUST00000005953.4
sulfide quinone reductase-like (yeast)
chr16_+_96235801 0.38 ENSMUST00000113800.2
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5
chr2_+_4400958 0.38 ENSMUST00000075767.7
FERM domain containing 4A
chr7_+_122219469 0.38 ENSMUST00000033152.4
calcineurin-like EF hand protein 2
chr12_+_81631369 0.38 ENSMUST00000036116.5
tetratricopeptide repeat domain 9
chr5_-_120887582 0.38 ENSMUST00000086368.5
2'-5' oligoadenylate synthetase 1G
chr13_-_92131494 0.37 ENSMUST00000099326.3
ENSMUST00000146492.1
RAS protein-specific guanine nucleotide-releasing factor 2
chr12_+_32953874 0.37 ENSMUST00000076698.5
synaptophysin-like protein
chr9_+_53405280 0.37 ENSMUST00000005262.1
RIKEN cDNA 4930550C14 gene
chr2_+_155381808 0.36 ENSMUST00000043237.7
ENSMUST00000174685.1
transformation related protein 53 inducible nuclear protein 2
chr15_-_58364148 0.36 ENSMUST00000068515.7
annexin A13
chrX_-_134746913 0.34 ENSMUST00000096324.2
predicted gene 10344
chr5_+_90518932 0.34 ENSMUST00000113179.2
ENSMUST00000128740.1
afamin
chr15_+_25773985 0.34 ENSMUST00000125667.1
myosin X
chr17_-_37280418 0.33 ENSMUST00000077585.2
olfactory receptor 99
chr8_+_62951195 0.33 ENSMUST00000118003.1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan 3
chr10_+_73821937 0.33 ENSMUST00000134009.2
ENSMUST00000125006.2
ENSMUST00000177420.1
protocadherin 15
chr4_-_19922599 0.33 ENSMUST00000029900.5
ATPase, H+ transporting, lysosomal V0 subunit D2
chr13_-_92030897 0.32 ENSMUST00000149630.1
RAS protein-specific guanine nucleotide-releasing factor 2
chr9_-_21312255 0.31 ENSMUST00000115433.3
ENSMUST00000003397.7
adaptor protein complex AP-1, mu 2 subunit
chr9_+_78191966 0.31 ENSMUST00000034903.5
glutathione S-transferase, alpha 4
chrX_+_103356464 0.31 ENSMUST00000116547.2
cysteine-rich hydrophobic domain 1
chr6_+_47244359 0.31 ENSMUST00000060839.6
contactin associated protein-like 2
chr4_+_102570065 0.31 ENSMUST00000097950.2
phosphodiesterase 4B, cAMP specific
chrX_-_163761323 0.31 ENSMUST00000059320.2
ring finger protein 138, retrogene 1
chr2_+_52038005 0.30 ENSMUST00000065927.5
tumor necrosis factor alpha induced protein 6
chr7_-_3915501 0.30 ENSMUST00000038176.8
ENSMUST00000090689.4
leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
chr3_+_51661167 0.30 ENSMUST00000099106.3
microsomal glutathione S-transferase 2
chr8_+_105827721 0.30 ENSMUST00000034365.4
translin-associated factor X (Tsnax) interacting protein 1
chr6_+_29471437 0.30 ENSMUST00000171317.1
predicted gene 9047
chr13_-_54565299 0.30 ENSMUST00000153065.1
ENSMUST00000126295.1
ENSMUST00000143144.1
ENSMUST00000132136.1
RIKEN cDNA 4833439L19 gene
chr13_-_62371936 0.28 ENSMUST00000107989.3
predicted gene 3604
chr4_+_3940747 0.28 ENSMUST00000119403.1
coiled-coil-helix-coiled-coil-helix domain containing 7
chr5_+_66968559 0.28 ENSMUST00000127184.1
LIM and calponin homology domains 1
chr7_-_3502465 0.28 ENSMUST00000065703.7
T cell-interacting, activating receptor on myeloid cells 1
chr7_+_66079643 0.28 ENSMUST00000101801.5
VCP-interacting membrane protein
chr4_-_24851079 0.28 ENSMUST00000084781.5
ENSMUST00000108218.3
kelch-like 32
chr10_+_34297421 0.28 ENSMUST00000047935.6
TSPY-like 4
chr16_-_26526744 0.27 ENSMUST00000165687.1
transmembrane protein 207
chr9_+_5298517 0.27 ENSMUST00000027015.5
caspase 1
chr4_+_117096049 0.27 ENSMUST00000030443.5
patched homolog 2
chr7_-_3845050 0.27 ENSMUST00000108615.3
ENSMUST00000119469.1
paired-Ig-like receptor A2
chr5_+_25516061 0.27 ENSMUST00000045016.7
chaperonin containing TCP1, subunit 8 (theta)-like 1
chr17_+_21555046 0.27 ENSMUST00000079242.3
zinc finger protein 52
chr13_+_30136529 0.27 ENSMUST00000152798.1
membrane bound O-acyltransferase domain containing 1
chr2_-_104742802 0.26 ENSMUST00000028595.7
DEP domain containing 7
chr8_+_62951361 0.26 ENSMUST00000119068.1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan 3
chr1_-_131276914 0.26 ENSMUST00000161764.1
inhibitor of kappaB kinase epsilon
chr1_-_172632931 0.26 ENSMUST00000027826.5
dual specificity phosphatase 23
chr18_+_37473538 0.26 ENSMUST00000050034.1
protocadherin beta 15
chr18_+_51117754 0.25 ENSMUST00000116639.2
proline rich 16
chr14_+_29968308 0.25 ENSMUST00000112268.1
selenoprotein K
chr3_-_133234886 0.25 ENSMUST00000147041.3
ENSMUST00000161022.2
Rho guanine nucleotide exchange factor (GEF) 38
chr6_+_125349699 0.25 ENSMUST00000032491.8
tumor necrosis factor receptor superfamily, member 1a
chr5_+_104459450 0.25 ENSMUST00000086831.3
polycystic kidney disease 2
chr6_-_125380793 0.25 ENSMUST00000042647.6
pleckstrin homology domain containing, family G (with RhoGef domain) member 6
chr10_+_75037066 0.25 ENSMUST00000147802.1
ENSMUST00000020391.5
RAB36, member RAS oncogene family
chr17_-_40794063 0.25 ENSMUST00000131699.1
ENSMUST00000024724.7
ENSMUST00000144243.1
cysteine-rich secretory protein 2
chr3_-_64287417 0.25 ENSMUST00000170244.1
ENSMUST00000176328.1
vomeronasal 2, receptor 3
chr13_+_23555023 0.24 ENSMUST00000045301.6
histone cluster 1, H1d
chr16_+_58995404 0.24 ENSMUST00000073320.2
olfactory receptor 183
chr2_+_174450678 0.24 ENSMUST00000016399.5
tubulin, beta 1 class VI
chr5_+_8046077 0.24 ENSMUST00000088786.4
sorcin
chrX_+_36195950 0.24 ENSMUST00000115257.1
zinc finger, CCHC domain containing 12
chr6_+_108783059 0.24 ENSMUST00000032196.6
ADP-ribosylation factor-like 8B
chr5_+_17574268 0.24 ENSMUST00000030568.7
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr3_+_28781305 0.24 ENSMUST00000060500.7
eukaryotic translation initiation factor 5A2
chr6_+_71282280 0.24 ENSMUST00000080949.7
lysine-rich coiled-coil 1
chr15_+_85510812 0.24 ENSMUST00000079690.2
predicted pseudogene 4825
chr17_+_47436731 0.24 ENSMUST00000150819.2
expressed sequence AI661453
chr14_-_25927250 0.23 ENSMUST00000100811.5
transmembrane protein 254a
chr2_-_5063996 0.23 ENSMUST00000114996.1
optineurin
chr14_-_70429072 0.23 ENSMUST00000048129.4
piwi-like RNA-mediated gene silencing 2
chr1_-_182517447 0.23 ENSMUST00000068505.8
calpain 2
chr3_-_14778452 0.22 ENSMUST00000094365.4
carbonic anhydrase 1
chr15_+_77477044 0.22 ENSMUST00000060551.2
ENSMUST00000119997.1
apolipoprotein L 10A
chr4_-_129378116 0.22 ENSMUST00000030610.2
zinc finger and BTB domain containing 8a
chr18_+_46741903 0.22 ENSMUST00000025357.7
adaptor-related protein complex 3, sigma 1 subunit
chr6_-_56923927 0.22 ENSMUST00000031793.5
5'-nucleotidase, cytosolic III
chr2_+_132686931 0.21 ENSMUST00000061891.4
RIKEN cDNA 1110034G24 gene
chr5_+_66968416 0.21 ENSMUST00000038188.7
LIM and calponin homology domains 1
chrX_-_38635066 0.21 ENSMUST00000058265.7
C1GALT1-specific chaperone 1
chr8_+_113643206 0.21 ENSMUST00000034219.4
ENSMUST00000095173.1
synaptonemal complex central element protein 1 like
chr11_-_29515017 0.21 ENSMUST00000133103.1
ENSMUST00000039900.3
prolyl-tRNA synthetase domain containing 1
chr13_-_53286052 0.21 ENSMUST00000021918.8
receptor tyrosine kinase-like orphan receptor 2
chr4_-_138326234 0.21 ENSMUST00000105817.3
ENSMUST00000030536.6
PTEN induced putative kinase 1
chr2_+_69135799 0.21 ENSMUST00000041865.7
nitric oxide synthase trafficker
chr2_-_164651763 0.21 ENSMUST00000099095.3
WAP four-disulfide core domain 9
chr11_+_113657375 0.21 ENSMUST00000148736.1
ENSMUST00000142069.1
ENSMUST00000134418.1
component of oligomeric golgi complex 1
chr6_-_115592571 0.21 ENSMUST00000112957.1
RIKEN cDNA 2510049J12 gene
chrX_+_36195938 0.21 ENSMUST00000048067.3
zinc finger, CCHC domain containing 12
chr18_+_37447641 0.20 ENSMUST00000052387.3
protocadherin beta 14
chr5_-_115436508 0.20 ENSMUST00000078701.3
RIKEN cDNA 4930430O22 gene
chr13_+_94083490 0.20 ENSMUST00000156071.1
lipoma HMGIC fusion partner-like 2
chr2_-_60722636 0.20 ENSMUST00000028348.2
ENSMUST00000112517.1
integrin beta 6
chr3_-_121643485 0.20 ENSMUST00000050571.4
RIKEN cDNA A730020M07 gene
chr14_-_55660397 0.20 ENSMUST00000002400.6
magnesium-dependent phosphatase 1
chr7_-_142661305 0.20 ENSMUST00000105936.1
insulin-like growth factor 2
chr1_-_63214543 0.20 ENSMUST00000050536.7
G protein-coupled receptor 1
chr11_+_115187481 0.20 ENSMUST00000100235.2
ENSMUST00000061450.6
transmembrane protein 104
chr4_-_49549523 0.20 ENSMUST00000029987.9
aldolase B, fructose-bisphosphate
chr9_-_117251801 0.20 ENSMUST00000172564.1
RNA binding motif, single stranded interacting protein
chr9_+_86743641 0.20 ENSMUST00000179574.1
protease, serine, 35
chr10_-_89533550 0.20 ENSMUST00000105297.1
nuclear receptor subfamily 1, group H, member 4
chr11_-_114989854 0.19 ENSMUST00000045075.2
CD300 molecule-like family member d
chr4_+_121039385 0.19 ENSMUST00000030372.5
collagen, type IX, alpha 2
chr2_-_106002008 0.19 ENSMUST00000155811.1
DnaJ (Hsp40) homolog, subfamily C, member 24
chr16_+_17208135 0.19 ENSMUST00000169803.1
RIMS binding protein 3
chr12_+_71831064 0.19 ENSMUST00000085299.2
dishevelled associated activator of morphogenesis 1
chrX_-_103623704 0.19 ENSMUST00000130063.1
ENSMUST00000125419.1
Ftx transcript, Xist regulator (non-protein coding)
chr6_+_38381469 0.19 ENSMUST00000162554.1
ENSMUST00000161751.1
tetratricopeptide repeat domain 26
chr8_+_84908560 0.19 ENSMUST00000003910.6
ENSMUST00000109744.1
deoxyribonuclease II alpha
chr9_+_54538984 0.19 ENSMUST00000060242.5
ENSMUST00000118413.1
SH2 domain containing 7
chr5_+_20702129 0.19 ENSMUST00000101556.4
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr6_+_30723541 0.19 ENSMUST00000115127.1
mesoderm specific transcript
chr1_-_15892657 0.19 ENSMUST00000040695.4
somatomedin B and thrombospondin, type 1 domain containing
chr13_-_54611274 0.19 ENSMUST00000049575.7
clathrin, light polypeptide (Lcb)
chr9_+_38719024 0.19 ENSMUST00000129598.1
von Willebrand factor A domain containing 5A
chr4_+_58285930 0.19 ENSMUST00000081919.5
ENSMUST00000102893.3
ENSMUST00000084578.5
ENSMUST00000098057.3
ENSMUST00000179951.1
ENSMUST00000098059.3
ENSMUST00000177951.1
muscle, skeletal, receptor tyrosine kinase
chr2_+_69790968 0.19 ENSMUST00000180290.1
phosphatase, orphan 2
chr12_+_24651346 0.19 ENSMUST00000020982.5
Kruppel-like factor 11
chr9_-_96631487 0.19 ENSMUST00000128346.1
ENSMUST00000034984.6
RAS p21 protein activator 2
chr4_+_152115934 0.19 ENSMUST00000025706.3
tumor necrosis factor receptor superfamily, member 25
chr8_+_46986913 0.18 ENSMUST00000039840.7
ENSMUST00000119686.1
ectonucleotide pyrophosphatase/phosphodiesterase 6
chr1_-_171294937 0.18 ENSMUST00000111302.3
ENSMUST00000080001.2
ubiquitin-fold modifier conjugating enzyme 1
chr8_+_71887264 0.18 ENSMUST00000034259.7
zinc finger protein 709
chr5_-_116024475 0.18 ENSMUST00000111999.1
protein kinase, AMP-activated, beta 1 non-catalytic subunit
chr1_-_36244245 0.18 ENSMUST00000046875.7
UDP-glucose glycoprotein glucosyltransferase 1
chr16_+_38562806 0.18 ENSMUST00000171687.1
ENSMUST00000002924.8
transmembrane protein 39a
chr11_-_99389351 0.18 ENSMUST00000103131.4
keratin 10
chr3_-_133234939 0.18 ENSMUST00000161932.1
Rho guanine nucleotide exchange factor (GEF) 38
chr6_-_67535783 0.18 ENSMUST00000058178.4
tumor-associated calcium signal transducer 2
chr14_-_63271682 0.18 ENSMUST00000132122.1
GATA binding protein 4
chr10_-_83648713 0.18 ENSMUST00000020500.7
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2
chr4_+_141010644 0.17 ENSMUST00000071977.8
microfibrillar-associated protein 2
chr5_+_108369858 0.17 ENSMUST00000100944.2
predicted gene 10419
chr11_-_115062177 0.17 ENSMUST00000062787.7
CD300e antigen
chr8_-_70632419 0.17 ENSMUST00000110103.1
growth differentiation factor 15
chr4_+_12906838 0.17 ENSMUST00000143186.1
ENSMUST00000183345.1
triple QxxK/R motif containing
chr11_+_103133333 0.17 ENSMUST00000124928.1
ENSMUST00000062530.4
hexamethylene bis-acetamide inducible 2
chr9_-_64726583 0.17 ENSMUST00000168366.1
RAB11a, member RAS oncogene family
chr1_+_40324570 0.17 ENSMUST00000095020.3
interleukin 1 receptor-like 2
chrX_+_159708593 0.17 ENSMUST00000080394.6
SH3-domain kinase binding protein 1
chr9_+_86743616 0.17 ENSMUST00000036426.6
protease, serine, 35
chrX_-_49886401 0.17 ENSMUST00000070304.2
olfactory receptor 1322
chr8_+_92827273 0.17 ENSMUST00000034187.7
matrix metallopeptidase 2
chr12_-_98259416 0.17 ENSMUST00000021390.7
galactosylceramidase
chr14_+_62663665 0.17 ENSMUST00000171692.1
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 3
chr11_+_5569679 0.17 ENSMUST00000109856.1
ENSMUST00000109855.1
ENSMUST00000118112.2
ankyrin repeat domain 36
chr4_+_98546710 0.17 ENSMUST00000102792.3
InaD-like (Drosophila)
chr3_-_98753465 0.16 ENSMUST00000094050.4
ENSMUST00000090743.6
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3
chr7_+_92062392 0.16 ENSMUST00000098308.2
discs, large homolog 2 (Drosophila)
chr7_+_101905837 0.16 ENSMUST00000033131.6
late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
chr5_-_87140318 0.16 ENSMUST00000067790.6
ENSMUST00000113327.1
UDP glucuronosyltransferase 2 family, polypeptide B5
chr16_+_72663143 0.16 ENSMUST00000023600.7
roundabout homolog 1 (Drosophila)
chr17_+_85028347 0.16 ENSMUST00000024944.7
solute carrier family 3, member 1
chr5_+_143403819 0.16 ENSMUST00000110731.2
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
chr11_+_109413917 0.16 ENSMUST00000055404.7
RIKEN cDNA 9930022D16 gene
chr18_+_84851338 0.16 ENSMUST00000160180.1
cytochrome b-5
chr3_+_127633134 0.16 ENSMUST00000029587.7
neurogenin 2

Network of associatons between targets according to the STRING database.

First level regulatory network of Hoxa5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.7 GO:0002838 negative regulation of response to tumor cell(GO:0002835) negative regulation of immune response to tumor cell(GO:0002838)
0.3 1.8 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.2 0.6 GO:0019343 cysteine biosynthetic process via cystathionine(GO:0019343)
0.2 0.7 GO:0072272 proximal/distal pattern formation involved in metanephric nephron development(GO:0072272)
0.2 0.5 GO:0042197 dichloromethane metabolic process(GO:0018900) chlorinated hydrocarbon metabolic process(GO:0042196) halogenated hydrocarbon metabolic process(GO:0042197)
0.2 0.5 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
0.2 0.5 GO:0010716 negative regulation of extracellular matrix disassembly(GO:0010716)
0.1 0.4 GO:2000077 positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161) positive regulation of establishment of Sertoli cell barrier(GO:1904446) negative regulation of type B pancreatic cell development(GO:2000077)
0.1 0.6 GO:0070459 prolactin secretion(GO:0070459)
0.1 0.4 GO:0009726 detection of nodal flow(GO:0003127) detection of endogenous stimulus(GO:0009726)
0.1 0.3 GO:0050973 detection of mechanical stimulus involved in equilibrioception(GO:0050973)
0.1 0.9 GO:0071231 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713) cellular response to folic acid(GO:0071231)
0.1 0.3 GO:0070676 intralumenal vesicle formation(GO:0070676) negative regulation of early endosome to late endosome transport(GO:2000642)
0.1 0.3 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.1 0.4 GO:2000327 regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
0.1 0.2 GO:0043181 vacuolar sequestering(GO:0043181)
0.1 0.3 GO:0007207 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.1 0.3 GO:0009957 epidermal cell fate specification(GO:0009957)
0.1 0.9 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 0.2 GO:0034971 histone H3-R17 methylation(GO:0034971)
0.1 0.3 GO:0061623 glycolytic process from galactose(GO:0061623)
0.1 0.4 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.1 0.3 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.1 0.2 GO:0061026 septum secundum development(GO:0003285) cardiac muscle tissue regeneration(GO:0061026) negative regulation of connective tissue replacement(GO:1905204)
0.1 0.2 GO:0000966 RNA 5'-end processing(GO:0000966)
0.1 0.2 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.1 0.6 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1 0.2 GO:1903383 neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036482) positive regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902958) regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903383) negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903384)
0.1 0.5 GO:0071294 cellular response to zinc ion(GO:0071294)
0.0 0.2 GO:0061624 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624) glycolytic process through fructose-1-phosphate(GO:0061625)
0.0 0.2 GO:0008594 photoreceptor cell morphogenesis(GO:0008594)
0.0 0.2 GO:0003350 pulmonary myocardium development(GO:0003350)
0.0 0.2 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.0 0.2 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.0 0.1 GO:1903334 positive regulation of protein folding(GO:1903334)
0.0 0.1 GO:1904959 regulation of electron carrier activity(GO:1904732) regulation of cytochrome-c oxidase activity(GO:1904959)
0.0 0.2 GO:2001183 negative regulation of interleukin-12 secretion(GO:2001183)
0.0 0.2 GO:0010796 regulation of multivesicular body size(GO:0010796)
0.0 0.2 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.0 0.2 GO:1900019 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.0 0.4 GO:0051026 chiasma assembly(GO:0051026)
0.0 0.1 GO:0060300 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874) regulation of cytokine activity(GO:0060300) negative regulation of sensory perception of pain(GO:1904057)
0.0 0.2 GO:0045905 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0 0.2 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 0.1 GO:2000313 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.0 0.2 GO:1900095 regulation of dosage compensation by inactivation of X chromosome(GO:1900095)
0.0 0.2 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.0 0.1 GO:0046368 GDP-L-fucose metabolic process(GO:0046368)
0.0 0.1 GO:0072235 distal convoluted tubule development(GO:0072025) metanephric distal convoluted tubule development(GO:0072221) metanephric distal tubule development(GO:0072235)
0.0 0.2 GO:0090191 negative regulation of branching involved in ureteric bud morphogenesis(GO:0090191)
0.0 0.2 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.2 GO:1901844 regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844)
0.0 0.1 GO:0006548 histidine catabolic process(GO:0006548)
0.0 0.1 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.0 0.1 GO:0006742 NADP catabolic process(GO:0006742)
0.0 0.1 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.1 GO:0071707 immunoglobulin heavy chain V-D-J recombination(GO:0071707)
0.0 0.2 GO:0021993 initiation of neural tube closure(GO:0021993)
0.0 0.1 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.0 0.1 GO:1905035 regulation of antifungal innate immune response(GO:1905034) negative regulation of antifungal innate immune response(GO:1905035)
0.0 0.2 GO:0044375 regulation of peroxisome size(GO:0044375)
0.0 0.2 GO:1990592 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.1 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.0 0.2 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.2 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.0 0.2 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.1 GO:1904566 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.0 0.1 GO:0031335 regulation of sulfur amino acid metabolic process(GO:0031335)
0.0 0.1 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.2 GO:0038044 transforming growth factor-beta secretion(GO:0038044)
0.0 0.1 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.0 0.1 GO:0045994 regulation of translational initiation by iron(GO:0006447) positive regulation of translational initiation by iron(GO:0045994)
0.0 0.1 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.0 0.1 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.0 0.1 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
0.0 0.4 GO:0048012 hepatocyte growth factor receptor signaling pathway(GO:0048012)
0.0 0.2 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.0 0.2 GO:0032439 endosome localization(GO:0032439)
0.0 0.1 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.0 0.2 GO:0019695 choline metabolic process(GO:0019695)
0.0 0.2 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729)
0.0 1.0 GO:0010107 potassium ion import(GO:0010107)
0.0 0.1 GO:0061344 regulation of cell adhesion involved in heart morphogenesis(GO:0061344) positive regulation of ephrin receptor signaling pathway(GO:1901189)
0.0 0.4 GO:1901538 DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538)
0.0 0.1 GO:0019085 early viral transcription(GO:0019085)
0.0 0.7 GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.0 0.1 GO:0019532 oxalate transport(GO:0019532)
0.0 0.2 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.0 0.1 GO:0002270 plasmacytoid dendritic cell activation(GO:0002270)
0.0 0.1 GO:0045054 constitutive secretory pathway(GO:0045054)
0.0 0.1 GO:0001830 trophectodermal cell fate commitment(GO:0001830)
0.0 0.1 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.1 GO:0010966 regulation of phosphate transport(GO:0010966)
0.0 0.1 GO:1901079 positive regulation of relaxation of muscle(GO:1901079)
0.0 0.1 GO:0060336 negative regulation of response to interferon-gamma(GO:0060331) negative regulation of interferon-gamma-mediated signaling pathway(GO:0060336) pancreatic stellate cell proliferation(GO:0072343) regulation of pancreatic stellate cell proliferation(GO:2000229)
0.0 0.1 GO:0060295 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108) regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.0 0.1 GO:0007468 regulation of rhodopsin gene expression(GO:0007468)
0.0 0.2 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.1 GO:0009816 defense response to bacterium, incompatible interaction(GO:0009816) regulation of defense response to bacterium, incompatible interaction(GO:1902477)
0.0 0.3 GO:0051645 Golgi localization(GO:0051645)
0.0 0.1 GO:0044830 modulation by host of viral RNA genome replication(GO:0044830)
0.0 0.1 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.0 0.1 GO:0051324 meiotic prophase I(GO:0007128) prophase(GO:0051324)
0.0 0.1 GO:0097680 double-strand break repair via classical nonhomologous end joining(GO:0097680)
0.0 0.1 GO:0050916 sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
0.0 0.1 GO:1903207 neuron death in response to hydrogen peroxide(GO:0036476) regulation of hydrogen peroxide-induced neuron death(GO:1903207) negative regulation of hydrogen peroxide-induced neuron death(GO:1903208)
0.0 0.6 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.2 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.0 0.2 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.2 GO:0006590 thyroid hormone generation(GO:0006590)
0.0 0.1 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.1 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.1 GO:1902669 positive regulation of axon guidance(GO:1902669)
0.0 0.5 GO:0090662 ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.0 0.2 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.0 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0 0.2 GO:0016540 protein autoprocessing(GO:0016540)
0.0 0.1 GO:0035878 nail development(GO:0035878)
0.0 0.3 GO:0050907 detection of chemical stimulus involved in sensory perception(GO:0050907)
0.0 0.1 GO:0021853 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0 0.6 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.2 GO:0008272 sulfate transport(GO:0008272)
0.0 0.1 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.0 0.3 GO:0019370 leukotriene biosynthetic process(GO:0019370)
0.0 0.1 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.0 0.1 GO:0042435 indole-containing compound biosynthetic process(GO:0042435)
0.0 0.1 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.1 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.0 0.1 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.3 GO:0099514 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.0 GO:0002352 B cell negative selection(GO:0002352)
0.0 0.2 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 0.0 GO:0070495 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.0 0.2 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.0 GO:0002461 tolerance induction dependent upon immune response(GO:0002461)
0.0 0.1 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.0 GO:1904578 response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579)
0.0 0.1 GO:0014004 microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.0 0.2 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0 0.1 GO:0032074 negative regulation of nuclease activity(GO:0032074)
0.0 1.1 GO:0007608 sensory perception of smell(GO:0007608)
0.0 0.1 GO:0042373 vitamin K metabolic process(GO:0042373)
0.0 0.1 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.0 0.0 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.0 0.2 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.0 0.2 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.0 0.0 GO:0099552 trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553) regulation of intracellular calcium activated chloride channel activity(GO:1902938)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.1 1.0 GO:0045098 type III intermediate filament(GO:0045098)
0.1 0.4 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.1 0.4 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.1 0.2 GO:0042584 chromaffin granule membrane(GO:0042584)
0.1 0.3 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.1 0.2 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.1 0.3 GO:0098553 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.1 0.5 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.2 GO:0097425 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 1.2 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.2 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 1.8 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.2 GO:1990923 PET complex(GO:1990923)
0.0 0.9 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.1 GO:0035841 new growing cell tip(GO:0035841)
0.0 0.4 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.2 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.8 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.1 GO:0042583 chromaffin granule(GO:0042583)
0.0 0.1 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.0 0.2 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.1 GO:0000814 ESCRT II complex(GO:0000814)
0.0 0.2 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.1 GO:0043202 lysosomal lumen(GO:0043202)
0.0 0.5 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.5 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.3 GO:0032009 early phagosome(GO:0032009)
0.0 0.2 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.3 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.1 GO:0045293 mRNA editing complex(GO:0045293)
0.0 0.5 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.3 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.1 GO:1902636 kinociliary basal body(GO:1902636)
0.0 0.1 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.1 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.0 0.1 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.0 0.1 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.3 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.2 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 0.1 GO:1990037 Lewy body core(GO:1990037)
0.0 0.1 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.1 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.1 GO:1990584 cardiac Troponin complex(GO:1990584)
0.0 0.1 GO:0032807 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) DNA ligase IV complex(GO:0032807)
0.0 0.2 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.1 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.0 GO:0031021 interphase microtubule organizing center(GO:0031021)
0.0 0.2 GO:0031143 pseudopodium(GO:0031143)
0.0 0.3 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.1 GO:0030897 HOPS complex(GO:0030897)
0.0 0.9 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.1 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.2 GO:0033202 DNA helicase complex(GO:0033202)
0.0 0.2 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.7 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.3 1.8 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.2 0.6 GO:0098809 nitrite reductase activity(GO:0098809)
0.2 1.0 GO:0004850 uridine phosphorylase activity(GO:0004850)
0.2 0.6 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.2 0.5 GO:0047651 hydrolase activity, acting on acid halide bonds(GO:0016824) hydrolase activity, acting on acid halide bonds, in C-halide compounds(GO:0019120) alkylhalidase activity(GO:0047651)
0.1 0.4 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.1 0.4 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.1 0.3 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.1 0.3 GO:0005119 smoothened binding(GO:0005119) hedgehog receptor activity(GO:0008158)
0.1 0.3 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.1 0.9 GO:0051870 methotrexate binding(GO:0051870)
0.1 0.4 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.1 0.3 GO:0034584 piRNA binding(GO:0034584)
0.1 0.3 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.1 0.3 GO:0048763 calcium-induced calcium release activity(GO:0048763)
0.1 0.2 GO:0071568 UFM1 transferase activity(GO:0071568)
0.1 0.2 GO:0008431 vitamin E binding(GO:0008431)
0.1 0.2 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.1 0.2 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.1 0.2 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.1 0.2 GO:0046923 ER retention sequence binding(GO:0046923)
0.1 0.3 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.2 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.0 0.2 GO:0033883 pyridoxal phosphatase activity(GO:0033883)
0.0 0.4 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 0.1 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.0 0.2 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.0 0.2 GO:0038181 bile acid receptor activity(GO:0038181)
0.0 0.1 GO:0005502 11-cis retinal binding(GO:0005502)
0.0 0.3 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.5 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.4 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 0.2 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.2 GO:0070051 fibrinogen binding(GO:0070051)
0.0 0.3 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.0 0.4 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.8 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.1 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.0 0.1 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.1 GO:0004155 6,7-dihydropteridine reductase activity(GO:0004155)
0.0 0.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.5 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.2 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.1 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.0 0.1 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.6 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.1 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.1 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.2 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.2 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.6 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.8 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.2 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 0.1 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.1 GO:0033699 DNA 5'-adenosine monophosphate hydrolase activity(GO:0033699)
0.0 0.1 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.0 0.1 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0 0.1 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.3 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.3 GO:0050700 CARD domain binding(GO:0050700)
0.0 1.4 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.1 GO:0000401 open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402)
0.0 0.1 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 0.2 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.0 0.1 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.3 GO:0070330 aromatase activity(GO:0070330)
0.0 0.3 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.1 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.1 GO:0019776 Atg8 ligase activity(GO:0019776)
0.0 0.2 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.2 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.0 0.1 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.1 GO:0017116 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116)
0.0 0.1 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0 0.1 GO:0016531 copper chaperone activity(GO:0016531)
0.0 0.1 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.0 0.3 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.5 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.2 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.1 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.0 0.1 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.0 0.1 GO:0016841 ammonia-lyase activity(GO:0016841)
0.0 0.4 GO:0032183 SUMO binding(GO:0032183)
0.0 0.1 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.0 0.2 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.1 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.3 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.2 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.1 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.0 0.1 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.0 0.1 GO:0030172 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.0 0.1 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.3 GO:0008378 galactosyltransferase activity(GO:0008378)
0.0 0.1 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.0 1.7 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.2 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.4 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.0 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.1 GO:0008417 fucosyltransferase activity(GO:0008417)
0.0 0.0 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 0.2 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.1 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.0 0.0 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 1.2 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.2 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.1 GO:0044388 small protein activating enzyme binding(GO:0044388)
0.0 0.0 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 0.1 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.2 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.0 GO:0031687 PLC activating G-protein coupled glutamate receptor activity(GO:0001639) A2A adenosine receptor binding(GO:0031687) G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.7 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.7 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.3 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 2.8 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.3 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.5 NABA PROTEOGLYCANS Genes encoding proteoglycans

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 1.9 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.1 1.5 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 1.2 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.7 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.6 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.8 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.7 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.6 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.0 0.2 REACTOME OPSINS Genes involved in Opsins
0.0 0.3 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.9 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.4 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.2 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.3 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 1.0 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 0.5 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.2 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.2 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.1 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.3 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 0.2 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.5 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.5 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.4 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 0.2 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.1 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.1 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling