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12D miR HR13_24

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Results for Six6

Z-value: 0.92

Motif logo

Transcription factors associated with Six6

Gene Symbol Gene ID Gene Info
ENSMUSG00000021099.5 sine oculis-related homeobox 6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Six6mm10_v2_chr12_+_72939724_72939758-0.934.1e-05Click!

Activity profile of Six6 motif

Sorted Z-values of Six6 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr9_-_45204083 2.12 ENSMUST00000034599.8
transmembrane protease, serine 4
chr4_+_104766334 2.08 ENSMUST00000065072.6
complement component 8, beta polypeptide
chr4_+_134864536 2.02 ENSMUST00000030627.7
Rh blood group, D antigen
chr4_+_104766308 1.97 ENSMUST00000031663.3
complement component 8, beta polypeptide
chr2_-_35100677 1.74 ENSMUST00000045776.4
ENSMUST00000113050.3
expressed sequence AI182371
chr16_+_32756336 1.58 ENSMUST00000135753.1
mucin 4
chr14_+_75242287 1.53 ENSMUST00000022576.8
carboxypeptidase B2 (plasma)
chr4_+_138967112 1.51 ENSMUST00000116094.2
ring finger protein 186
chr16_+_32735886 1.50 ENSMUST00000132475.1
ENSMUST00000096106.3
mucin 4
chr16_+_23290464 1.33 ENSMUST00000115335.1
beta galactoside alpha 2,6 sialyltransferase 1
chr10_+_73821857 1.31 ENSMUST00000177128.1
ENSMUST00000064562.7
ENSMUST00000129404.2
ENSMUST00000105426.3
ENSMUST00000131321.2
ENSMUST00000126920.2
ENSMUST00000147189.2
ENSMUST00000105424.3
ENSMUST00000092420.6
ENSMUST00000105429.3
ENSMUST00000131724.2
ENSMUST00000152655.2
ENSMUST00000151116.2
ENSMUST00000155701.2
ENSMUST00000152819.2
ENSMUST00000125517.2
ENSMUST00000124046.1
ENSMUST00000149977.2
ENSMUST00000146682.1
ENSMUST00000177107.1
protocadherin 15
chr15_-_67113909 1.26 ENSMUST00000092640.5
ST3 beta-galactoside alpha-2,3-sialyltransferase 1
chr7_-_134938264 1.24 ENSMUST00000171394.1
family with sequence similarity 196, member A
chr8_-_38661508 1.24 ENSMUST00000118896.1
sarcoglycan zeta
chr7_+_30977043 1.21 ENSMUST00000058093.4
family with sequence similarity 187, member B
chr17_+_48247759 1.08 ENSMUST00000048065.5
triggering receptor expressed on myeloid cells 3
chr3_-_85722474 0.97 ENSMUST00000119077.1
family with sequence similarity 160, member A1
chr17_+_21657582 0.96 ENSMUST00000039726.7
RIKEN cDNA 3110052M02 gene
chr1_+_40266578 0.96 ENSMUST00000114795.1
interleukin 1 receptor, type I
chr11_+_78324200 0.85 ENSMUST00000102478.3
aldolase C, fructose-bisphosphate
chr17_-_28560704 0.84 ENSMUST00000114785.1
ENSMUST00000025062.3
colipase, pancreatic
chr4_-_24851079 0.83 ENSMUST00000084781.5
ENSMUST00000108218.3
kelch-like 32
chr7_-_119459266 0.82 ENSMUST00000033255.5
glycoprotein 2 (zymogen granule membrane)
chr16_-_52296924 0.79 ENSMUST00000167115.1
activated leukocyte cell adhesion molecule
chr12_-_113422730 0.78 ENSMUST00000177715.1
ENSMUST00000103426.1
immunoglobulin heavy constant mu
chr15_-_75894474 0.76 ENSMUST00000023237.6
nicotinate phosphoribosyltransferase domain containing 1
chr1_+_171419027 0.71 ENSMUST00000171362.1
thiosulfate sulfurtransferase (rhodanese)-like domain containing 1
chr11_-_105937798 0.68 ENSMUST00000183493.1
cytochrome b-561
chr3_-_106406090 0.68 ENSMUST00000029510.7
cDNA sequence BC051070
chr3_-_75270073 0.66 ENSMUST00000039047.4
serine (or cysteine) peptidase inhibitor, clade I, member 2
chr7_+_30232310 0.66 ENSMUST00000108193.1
ENSMUST00000108192.1
polymerase (RNA) II (DNA directed) polypeptide I
chr17_-_56717681 0.65 ENSMUST00000164907.1
vimentin-type intermediate filament associated coiled-coil protein
chr7_+_131032061 0.64 ENSMUST00000084509.3
deleted in malignant brain tumors 1
chr6_+_41458923 0.63 ENSMUST00000031910.7
protease, serine, 1 (trypsin 1)
chr9_-_119341390 0.63 ENSMUST00000139870.1
myeloid differentiation primary response gene 88
chr8_+_40423786 0.63 ENSMUST00000049389.4
ENSMUST00000128166.1
ENSMUST00000167766.1
zinc finger, DHHC domain containing 2
chr12_+_83987854 0.63 ENSMUST00000021649.7
acyl-CoA thioesterase 2
chr19_+_58759700 0.62 ENSMUST00000026081.3
pancreatic lipase-related protein 2
chr5_+_117319258 0.61 ENSMUST00000111967.1
V-set and immunoglobulin domain containing 10
chr9_+_104002546 0.60 ENSMUST00000035167.8
ENSMUST00000117054.1
nephronophthisis 3 (adolescent)
chr2_+_69790968 0.58 ENSMUST00000180290.1
phosphatase, orphan 2
chr5_-_108795352 0.57 ENSMUST00000004943.1
transmembrane emp24 protein transport domain containing
chr7_+_43950614 0.57 ENSMUST00000072204.4
kallikrein 1-related peptidase b8
chr6_-_40951826 0.56 ENSMUST00000073642.5
predicted gene 4744
chr15_-_74763567 0.55 ENSMUST00000040404.6
lymphocyte antigen 6 complex, locus D
chr8_-_106136792 0.54 ENSMUST00000146940.1
epithelial splicing regulatory protein 2
chr9_+_98422961 0.53 ENSMUST00000052068.9
retinol binding protein 1, cellular
chr6_-_41314700 0.52 ENSMUST00000064324.5
trypsin 5
chr5_+_23787691 0.49 ENSMUST00000030852.6
ENSMUST00000120869.1
ENSMUST00000117783.1
ENSMUST00000115113.2
RAD50 interactor 1
chr7_+_128062657 0.49 ENSMUST00000120355.1
ENSMUST00000106240.2
ENSMUST00000098015.3
integrin alpha M
chr4_-_43653560 0.48 ENSMUST00000107870.2
sperm associated antigen 8
chr18_+_56432116 0.48 ENSMUST00000070166.5
GRAM domain containing 3
chr17_+_25133385 0.47 ENSMUST00000040729.2
chloride channel 7
chr9_+_106222598 0.45 ENSMUST00000062241.9
toll-like receptor 9
chr5_+_90903864 0.45 ENSMUST00000075433.6
chemokine (C-X-C motif) ligand 2
chr1_-_9298499 0.45 ENSMUST00000132064.1
syntrophin, gamma 1
chrX_-_79517285 0.44 ENSMUST00000101410.2
predicted gene 7173
chr7_+_128062635 0.44 ENSMUST00000064821.7
ENSMUST00000106242.3
integrin alpha M
chr5_+_122206792 0.44 ENSMUST00000145854.1
hydrogen voltage-gated channel 1
chr4_-_134372529 0.44 ENSMUST00000030643.2
exostoses (multiple)-like 1
chr9_+_72958785 0.43 ENSMUST00000098567.2
ENSMUST00000034734.8
dyslexia susceptibility 1 candidate 1 homolog (human)
chr5_+_117363513 0.43 ENSMUST00000111959.1
WD repeat and SOCS box-containing 2
chrX_-_74373260 0.42 ENSMUST00000073067.4
ENSMUST00000037967.5
solute carrier family 10 (sodium/bile acid cotransporter family), member 3
chr13_-_56895737 0.42 ENSMUST00000022023.6
ENSMUST00000109871.1
transient receptor potential cation channel, subfamily C, member 7
chr13_+_112800878 0.41 ENSMUST00000016144.4
phosphatidic acid phosphatase type 2A
chr2_+_152293828 0.41 ENSMUST00000028963.7
ENSMUST00000144252.1
TBC1 domain family, member 20
chr11_-_83592981 0.41 ENSMUST00000019071.3
chemokine (C-C motif) ligand 6
chr19_+_11407652 0.40 ENSMUST00000072729.3
membrane-spanning 4-domains, subfamily A, member 4C
chr4_-_138624001 0.39 ENSMUST00000030533.5
von Willebrand factor A domain containing 5B1
chr7_-_100855403 0.39 ENSMUST00000156855.1
RELT tumor necrosis factor receptor
chr13_+_13590402 0.39 ENSMUST00000110559.1
lysosomal trafficking regulator
chrX_+_159627265 0.39 ENSMUST00000112456.2
SH3-domain kinase binding protein 1
chr4_+_42318334 0.38 ENSMUST00000178192.1
predicted gene, 21598
chr19_+_46341118 0.38 ENSMUST00000128041.1
transmembrane protein 180
chr8_+_27023793 0.37 ENSMUST00000033873.7
ER lipid raft associated 2
chr16_+_84774123 0.37 ENSMUST00000114195.1
junction adhesion molecule 2
chr7_-_126676428 0.36 ENSMUST00000106373.1
sulfotransferase family 1A, phenol-preferring, member 1
chr15_+_98571004 0.36 ENSMUST00000023728.6
RIKEN cDNA 4930415O20 gene
chr7_-_30232186 0.36 ENSMUST00000006254.5
tubulin folding cofactor B
chr9_-_50528641 0.36 ENSMUST00000034570.5
6-pyruvoyl-tetrahydropterin synthase
chr7_-_104315455 0.35 ENSMUST00000106837.1
ENSMUST00000106839.2
ENSMUST00000070943.6
tripartite motif-containing 12A
chr5_-_88527841 0.33 ENSMUST00000087033.3
immunoglobulin joining chain
chr9_-_59353430 0.33 ENSMUST00000026265.6
Bardet-Biedl syndrome 4 (human)
chr11_-_11627824 0.32 ENSMUST00000081896.4
RIKEN cDNA 4930512M02 gene
chr7_+_128062698 0.32 ENSMUST00000119696.1
integrin alpha M
chr3_+_106547693 0.31 ENSMUST00000117469.1
ENSMUST00000067630.6
ENSMUST00000134396.1
ENSMUST00000144746.1
ENSMUST00000121034.1
ENSMUST00000029507.6
ENSMUST00000132923.1
ENSMUST00000151465.1
DNA-damage regulated autophagy modulator 2
chr9_-_88438940 0.30 ENSMUST00000165315.1
ENSMUST00000173039.1
sorting nexin 14
chr8_-_67910911 0.30 ENSMUST00000093468.5
pleckstrin and Sec7 domain containing 3
chr7_-_141168671 0.30 ENSMUST00000106033.3
ribonuclease/angiogenin inhibitor 1
chr11_+_100319880 0.29 ENSMUST00000049385.7
eukaryotic translation initiation factor 1
chr7_-_126676357 0.29 ENSMUST00000106371.1
ENSMUST00000106372.3
ENSMUST00000155419.1
sulfotransferase family 1A, phenol-preferring, member 1
chr16_-_65562686 0.29 ENSMUST00000004965.6
charged multivesicular body protein 2B
chr7_-_15839678 0.28 ENSMUST00000108513.3
oocyte specific homeobox 6
chr9_-_88438898 0.28 ENSMUST00000173011.1
ENSMUST00000174806.1
sorting nexin 14
chr4_-_42853888 0.28 ENSMUST00000107979.1
predicted gene 12429
chr19_-_23075853 0.28 ENSMUST00000181623.1
RIKEN cDNA C330002G04 gene
chr18_+_32815383 0.28 ENSMUST00000025237.3
thymic stromal lymphopoietin
chr2_+_106693185 0.27 ENSMUST00000111063.1
metallophosphoesterase domain containing 2
chr2_+_70661556 0.27 ENSMUST00000112201.1
ENSMUST00000028509.4
ENSMUST00000133432.1
ENSMUST00000112205.1
golgi reassembly stacking protein 2
chr10_-_81627797 0.26 ENSMUST00000042923.8
sirtuin 6
chr16_-_31275277 0.25 ENSMUST00000060188.7
protein phosphatase 1, regulatory (inhibitor) subunit 2
chr7_+_66839726 0.25 ENSMUST00000098382.3
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 17
chr1_+_45311538 0.25 ENSMUST00000087883.6
collagen, type III, alpha 1
chr12_+_8921598 0.25 ENSMUST00000020909.3
lysosomal-associated protein transmembrane 4A
chr7_+_50599180 0.24 ENSMUST00000119710.2
RIKEN cDNA 4933405O20 gene
chr5_+_21543525 0.23 ENSMUST00000035651.4
leucine rich repeat containing 17
chr11_+_60353324 0.23 ENSMUST00000070805.6
ENSMUST00000094140.2
ENSMUST00000108723.2
ENSMUST00000108722.4
leucine rich repeat containing 48
chr4_-_115781012 0.23 ENSMUST00000106521.1
testis expressed 38
chr18_+_12599894 0.23 ENSMUST00000169401.1
tetratricopeptide repeat domain 39C
chr5_+_122210134 0.23 ENSMUST00000100747.2
hydrogen voltage-gated channel 1
chrX_-_167102059 0.23 ENSMUST00000146929.1
predicted gene 15232
chr17_+_56717759 0.22 ENSMUST00000002452.6
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 11
chr13_+_94083490 0.22 ENSMUST00000156071.1
lipoma HMGIC fusion partner-like 2
chr9_+_77921908 0.22 ENSMUST00000133757.1
ELOVL family member 5, elongation of long chain fatty acids (yeast)
chr17_-_53539411 0.22 ENSMUST00000056198.3
protein phosphatase 2C-like domain containing 1
chr7_+_46847128 0.21 ENSMUST00000005051.4
lactate dehydrogenase A
chr8_+_71951038 0.21 ENSMUST00000131237.1
ENSMUST00000136516.1
ENSMUST00000109997.2
ENSMUST00000132848.1
zinc finger protein 961
chr13_-_90089060 0.21 ENSMUST00000161396.1
X-ray repair complementing defective repair in Chinese hamster cells 4
chr6_+_115675983 0.20 ENSMUST00000068960.9
RIKEN cDNA D830050J10 gene
chr7_+_30231884 0.20 ENSMUST00000019882.9
polymerase (RNA) II (DNA directed) polypeptide I
chr8_-_93197799 0.20 ENSMUST00000034172.7
carboxylesterase 1D
chr4_-_43653542 0.20 ENSMUST00000084646.4
sperm associated antigen 8
chr5_+_144244432 0.19 ENSMUST00000110695.1
brain protein I3
chr3_-_85887472 0.19 ENSMUST00000154148.1
ENSMUST00000033643.5
ADP-ribosylation factor interacting protein 1
glycosyltransferase 28 domain containing 2
chr13_-_49248146 0.18 ENSMUST00000119721.1
ENSMUST00000058196.6
sushi domain containing 3
chr17_-_29716969 0.18 ENSMUST00000129091.1
ENSMUST00000128751.1
coiled-coil domain containing 167
chr7_+_43690418 0.18 ENSMUST00000056329.6
kallikrein related-peptidase 14
chr2_+_131491764 0.17 ENSMUST00000028806.5
ENSMUST00000110179.2
ENSMUST00000110189.2
ENSMUST00000110182.2
ENSMUST00000110183.2
ENSMUST00000110186.2
ENSMUST00000110188.1
spermine oxidase
chr7_+_25897620 0.17 ENSMUST00000072438.6
ENSMUST00000005477.5
cytochrome P450, family 2, subfamily b, polypeptide 10
chr11_-_4849345 0.17 ENSMUST00000053079.6
ENSMUST00000109910.2
neurofibromatosis 2
chr18_+_74216118 0.16 ENSMUST00000025444.6
CXXC finger 1 (PHD domain)
chr8_-_94918012 0.16 ENSMUST00000077955.5
coiled-coil domain containing 102A
chr9_+_119341487 0.15 ENSMUST00000175743.1
ENSMUST00000176397.1
acetyl-Coenzyme A acyltransferase 1A
chr7_+_123123870 0.15 ENSMUST00000094053.5
trinucleotide repeat containing 6a
chr3_-_95133989 0.15 ENSMUST00000172572.2
ENSMUST00000173462.2
sodium channel modifier 1
chrX_+_103414461 0.14 ENSMUST00000033691.4
testis specific X-linked gene
chr19_+_55316313 0.14 ENSMUST00000095950.2
vesicle transport through interaction with t-SNAREs 1A
chr17_+_21690766 0.14 ENSMUST00000097384.1
predicted gene 10509
chr9_+_124121534 0.13 ENSMUST00000111442.1
ENSMUST00000171499.2
chemokine (C-C motif) receptor 5
chr9_+_58582240 0.13 ENSMUST00000177292.1
ENSMUST00000085651.5
neuroplastin
chr19_-_4625612 0.13 ENSMUST00000025823.3
RCE1 homolog, prenyl protein peptidase (S. cerevisiae)
chr9_+_58582397 0.13 ENSMUST00000176557.1
ENSMUST00000114121.4
ENSMUST00000177064.1
neuroplastin
chr10_-_78487842 0.13 ENSMUST00000069431.4
predicted gene 9978
chr1_-_59094885 0.13 ENSMUST00000097080.3
amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 11 (human)
chr4_+_5644084 0.13 ENSMUST00000054857.6
family with sequence similarity 110, member B
chr6_+_123123313 0.13 ENSMUST00000041779.6
C-type lectin domain family 4, member a2
chr17_+_43568096 0.12 ENSMUST00000167214.1
phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
chr19_-_32196393 0.12 ENSMUST00000151822.1
sphingomyelin synthase 1
chr5_-_100373484 0.12 ENSMUST00000182433.1
Sec31 homolog A (S. cerevisiae)
chr6_+_123123423 0.12 ENSMUST00000032248.7
C-type lectin domain family 4, member a2
chr16_+_29210108 0.12 ENSMUST00000162747.1
HRAS-like suppressor
chr14_+_123659971 0.12 ENSMUST00000049681.7
integrin, beta-like 1
chr11_+_117797660 0.12 ENSMUST00000106331.1
RIKEN cDNA 6030468B19 gene
chr1_-_23922283 0.12 ENSMUST00000027339.7
small ArfGAP 1
chr18_-_61911783 0.11 ENSMUST00000049378.8
ENSMUST00000166783.1
actin binding LIM protein family, member 3
chr11_-_8973266 0.11 ENSMUST00000154153.1
polycystic kidney disease 1 like 1
chr3_-_106547726 0.10 ENSMUST00000039153.7
ENSMUST00000148269.1
ENSMUST00000068301.4
choline/ethanolaminephosphotransferase 1
chr1_-_153851189 0.10 ENSMUST00000059607.6
RIKEN cDNA 5830403L16 gene
chr14_-_77036081 0.10 ENSMUST00000142300.1
laccase (multicopper oxidoreductase) domain containing 1
chr7_+_75610038 0.10 ENSMUST00000125771.1
A kinase (PRKA) anchor protein 13
chr14_+_29978337 0.09 ENSMUST00000016115.4
ARP8 actin-related protein 8
chr8_-_40634776 0.09 ENSMUST00000048898.10
ENSMUST00000174205.1
myotubularin related protein 7
chr11_+_58104229 0.09 ENSMUST00000108843.1
ENSMUST00000134896.1
CCR4-NOT transcription complex, subunit 8
chr1_+_165485168 0.09 ENSMUST00000111440.1
ENSMUST00000027852.8
ENSMUST00000111439.1
adenylate cyclase 10
chr3_+_146220955 0.09 ENSMUST00000039164.2
lysophosphatidic acid receptor 3
chr19_-_8218832 0.09 ENSMUST00000113298.2
solute carrier family 22. member 29
chr10_+_80603253 0.08 ENSMUST00000180350.1
secretory carrier membrane protein 4
chr2_+_129800451 0.08 ENSMUST00000165413.2
ENSMUST00000166282.2
serine/threonine kinase 35
chr17_+_43568269 0.08 ENSMUST00000024706.5
phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
chr18_+_62180119 0.08 ENSMUST00000067743.1
predicted gene 9949
chr7_+_110627650 0.08 ENSMUST00000033054.8
adrenomedullin
chr11_+_58104138 0.08 ENSMUST00000020822.5
CCR4-NOT transcription complex, subunit 8
chr2_-_13271268 0.07 ENSMUST00000137670.1
ENSMUST00000114791.2
Ras suppressor protein 1
chr9_-_121839460 0.07 ENSMUST00000135986.2
coiled-coil domain containing 13
chr2_-_13271419 0.07 ENSMUST00000028059.2
Ras suppressor protein 1
chr17_+_43568641 0.07 ENSMUST00000169694.1
phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
chr1_+_171682004 0.07 ENSMUST00000015499.7
ENSMUST00000068584.5
CD48 antigen
chr2_-_119029392 0.06 ENSMUST00000036470.7
ENSMUST00000110834.1
coiled-coil domain containing 32
chr5_+_140607334 0.06 ENSMUST00000031555.1
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr4_+_150148905 0.05 ENSMUST00000059893.7
solute carrier family 2 (facilitated glucose transporter), member 7
chr9_+_77636494 0.05 ENSMUST00000057781.7
kelch-like 31
chr7_-_118243564 0.05 ENSMUST00000179047.1
ENSMUST00000032891.8
SMG1 homolog, phosphatidylinositol 3-kinase-related kinase (C. elegans)
chr5_-_106926245 0.04 ENSMUST00000117588.1
HFM1, ATP-dependent DNA helicase homolog (S. cerevisiae)
chr1_+_60746358 0.03 ENSMUST00000027165.2
CD28 antigen
chr4_-_97584605 0.03 ENSMUST00000107067.1
RIKEN cDNA E130114P18 gene
chr8_-_86885222 0.03 ENSMUST00000034074.7
NEDD4 binding protein 1
chr14_-_51071442 0.02 ENSMUST00000048478.5
olfactory receptor 750
chr1_-_165634451 0.02 ENSMUST00000111435.2
ENSMUST00000068705.7
myelin protein zero-like 1
chr8_-_106573461 0.02 ENSMUST00000073722.5
predicted pseudogene 10073
chr8_+_85026833 0.02 ENSMUST00000047281.8
RIKEN cDNA 2310036O22 gene
chr17_+_43568475 0.02 ENSMUST00000167418.1
phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
chr17_-_23771543 0.02 ENSMUST00000086325.5
FLYWCH-type zinc finger 1
chr18_-_88927447 0.02 ENSMUST00000147313.1
suppressor of cytokine signaling 6
chr8_+_3393018 0.02 ENSMUST00000004684.6
ENSMUST00000145394.1
rho/rac guanine nucleotide exchange factor (GEF) 18
chr4_-_116651644 0.02 ENSMUST00000030455.8
aldo-keto reductase family 1, member A1 (aldehyde reductase)
chr7_-_24724237 0.02 ENSMUST00000081657.4
predicted gene 4763
chr3_-_9004686 0.01 ENSMUST00000120143.1
tumor protein D52
chr2_-_119029359 0.01 ENSMUST00000110833.1
coiled-coil domain containing 32
chr5_-_31154152 0.01 ENSMUST00000114632.1
ENSMUST00000114631.2
ENSMUST00000067186.6
ENSMUST00000137165.1
ENSMUST00000131391.1
ENSMUST00000141823.1
ENSMUST00000154241.1
MpV17 mitochondrial inner membrane protein
chr3_-_40509737 0.01 ENSMUST00000179966.1
RIKEN cDNA 1700017G19 gene

Network of associatons between targets according to the STRING database.

First level regulatory network of Six6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.5 3.1 GO:0002838 negative regulation of response to tumor cell(GO:0002835) negative regulation of immune response to tumor cell(GO:0002838)
0.5 1.5 GO:0003331 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.4 1.3 GO:0050973 detection of mechanical stimulus involved in equilibrioception(GO:0050973)
0.3 1.3 GO:1990743 protein sialylation(GO:1990743)
0.3 0.9 GO:0001193 maintenance of transcriptional fidelity during DNA-templated transcription elongation(GO:0001192) maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter(GO:0001193)
0.3 4.0 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.3 0.8 GO:0002344 peripheral B cell selection(GO:0002343) B cell affinity maturation(GO:0002344)
0.2 1.0 GO:0010286 heat acclimation(GO:0010286)
0.2 0.4 GO:0032741 positive regulation of interleukin-18 production(GO:0032741)
0.2 1.2 GO:0014004 microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.2 0.5 GO:0033189 response to vitamin A(GO:0033189)
0.2 0.8 GO:0002386 immune response in mucosal-associated lymphoid tissue(GO:0002386)
0.2 0.5 GO:0072425 signal transduction involved in G2 DNA damage checkpoint(GO:0072425) signal transduction involved in mitotic G2 DNA damage checkpoint(GO:0072434)
0.2 0.6 GO:0072566 chemokine (C-X-C motif) ligand 1 production(GO:0072566) regulation of chemokine (C-X-C motif) ligand 1 production(GO:2000338)
0.2 1.1 GO:0070945 neutrophil mediated killing of gram-negative bacterium(GO:0070945)
0.1 0.6 GO:0048496 maintenance of organ identity(GO:0048496)
0.1 0.4 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726) positive regulation of ER to Golgi vesicle-mediated transport(GO:1902953)
0.1 0.4 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.1 0.3 GO:0003245 cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.1 0.3 GO:0038108 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
0.1 0.6 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.1 0.7 GO:0071294 cellular response to zinc ion(GO:0071294)
0.1 0.2 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.1 0.8 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.1 0.4 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.1 0.3 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.0 0.2 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 0.3 GO:0034441 plasma lipoprotein particle oxidation(GO:0034441)
0.0 0.2 GO:0019244 lactate biosynthetic process from pyruvate(GO:0019244)
0.0 0.4 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729)
0.0 0.6 GO:0019377 glycolipid catabolic process(GO:0019377)
0.0 0.6 GO:0051923 sulfation(GO:0051923)
0.0 0.1 GO:0003127 detection of nodal flow(GO:0003127) detection of endogenous stimulus(GO:0009726)
0.0 0.2 GO:0046208 spermine catabolic process(GO:0046208)
0.0 0.6 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.2 GO:0042738 exogenous drug catabolic process(GO:0042738)
0.0 0.2 GO:0048539 bone marrow development(GO:0048539)
0.0 0.4 GO:0036159 inner dynein arm assembly(GO:0036159)
0.0 0.5 GO:0080184 response to stilbenoid(GO:0035634) response to phenylpropanoid(GO:0080184)
0.0 0.1 GO:2000110 negative regulation of macrophage apoptotic process(GO:2000110)
0.0 1.3 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.8 GO:0032094 response to food(GO:0032094)
0.0 0.3 GO:1901673 regulation of mitotic spindle assembly(GO:1901673)
0.0 0.1 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.2 GO:0034625 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.3 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.4 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.0 0.2 GO:0051103 DNA ligation involved in DNA repair(GO:0051103)
0.0 0.6 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.2 GO:0035330 regulation of hippo signaling(GO:0035330)
0.0 0.5 GO:0060445 branching involved in salivary gland morphogenesis(GO:0060445)
0.0 0.2 GO:0007320 insemination(GO:0007320)
0.0 0.7 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.4 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.2 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.2 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.1 GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883) adrenergic receptor signaling pathway involved in heart process(GO:0086023)
0.0 0.1 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.1 GO:0015747 urate transport(GO:0015747)
0.0 0.3 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 4.0 GO:0005579 membrane attack complex(GO:0005579)
0.2 0.6 GO:0097543 ciliary inversin compartment(GO:0097543)
0.2 1.2 GO:0016012 sarcoglycan complex(GO:0016012)
0.2 0.5 GO:0070939 Dsl1p complex(GO:0070939)
0.1 0.4 GO:0036019 endolysosome(GO:0036019)
0.1 1.4 GO:0000138 Golgi trans cisterna(GO:0000138)
0.1 3.1 GO:0031528 microvillus membrane(GO:0031528)
0.1 0.8 GO:0019815 B cell receptor complex(GO:0019815)
0.1 0.6 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.1 0.3 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.1 0.6 GO:0045098 type III intermediate filament(GO:0045098)
0.1 0.2 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.1 0.2 GO:0097447 dendritic tree(GO:0097447)
0.0 0.6 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.9 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.2 GO:0032807 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) DNA ligase IV complex(GO:0032807)
0.0 1.2 GO:0008305 integrin complex(GO:0008305)
0.0 0.3 GO:0034464 BBSome(GO:0034464)
0.0 0.3 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.8 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.2 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.2 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.3 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 1.1 GO:0032420 stereocilium(GO:0032420)
0.0 0.3 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.6 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.1 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 0.3 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.2 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.3 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.9 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.5 GO:0030173 integral component of Golgi membrane(GO:0030173)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.1 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.3 1.0 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.3 1.3 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.3 1.3 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.2 0.7 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
0.2 0.6 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.2 1.2 GO:0001851 complement component C3b binding(GO:0001851)
0.2 0.6 GO:0070976 TIR domain binding(GO:0070976)
0.1 0.6 GO:0033883 pyridoxal phosphatase activity(GO:0033883)
0.1 0.4 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.1 0.7 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.1 0.8 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 1.1 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.1 0.3 GO:0046969 histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969)
0.1 0.6 GO:0045322 unmethylated CpG binding(GO:0045322)
0.1 2.0 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.1 0.2 GO:0004771 sterol esterase activity(GO:0004771)
0.1 0.2 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.1 0.2 GO:0046592 polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901)
0.1 2.8 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 0.2 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.1 0.3 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 1.5 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.8 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.6 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.6 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.5 GO:0019841 retinol binding(GO:0019841)
0.0 0.3 GO:0008428 ribonuclease inhibitor activity(GO:0008428)
0.0 0.4 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.2 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.0 0.6 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.3 GO:0034452 dynactin binding(GO:0034452)
0.0 0.4 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.3 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847) calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.5 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.1 GO:0008410 acetyl-CoA C-acetyltransferase activity(GO:0003985) CoA-transferase activity(GO:0008410) palmitoyl-CoA oxidase activity(GO:0016401) C-acetyltransferase activity(GO:0016453)
0.0 0.1 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.1 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.0 0.6 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.9 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.0 0.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.2 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.4 GO:0008009 chemokine activity(GO:0008009)
0.0 0.2 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.1 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.1 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 1.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.1 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.0 0.1 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.2 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 1.6 PID IL1 PATHWAY IL1-mediated signaling events
0.0 2.3 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.4 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 5.7 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 4.0 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.1 1.1 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.1 0.6 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 0.9 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.4 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.1 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.8 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 1.0 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.6 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.4 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.8 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.4 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 1.6 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.2 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.0 0.1 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.0 0.5 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.2 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.3 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.6 REACTOME LIPID DIGESTION MOBILIZATION AND TRANSPORT Genes involved in Lipid digestion, mobilization, and transport
0.0 0.2 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 0.2 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin