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12D miR HR13_24

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Results for Nkx6-1_Evx1_Hesx1

Z-value: 0.88

Motif logo

Transcription factors associated with Nkx6-1_Evx1_Hesx1

Gene Symbol Gene ID Gene Info
ENSMUSG00000035187.8 NK6 homeobox 1
ENSMUSG00000005503.8 even-skipped homeobox 1
ENSMUSG00000040726.8 homeobox gene expressed in ES cells

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nkx6-1mm10_v2_chr5_-_101665195_101665226-0.303.7e-01Click!
Hesx1mm10_v2_chr14_+_27000362_270005070.186.0e-01Click!

Activity profile of Nkx6-1_Evx1_Hesx1 motif

Sorted Z-values of Nkx6-1_Evx1_Hesx1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr8_-_62123106 2.39 ENSMUST00000034052.6
ENSMUST00000034054.7
annexin A10
chr18_+_4993795 2.26 ENSMUST00000153016.1
supervillin
chr3_+_122044428 2.03 ENSMUST00000013995.8
ATP-binding cassette, sub-family A (ABC1), member 4
chr3_+_54361103 1.89 ENSMUST00000107985.3
ENSMUST00000117373.1
ENSMUST00000073012.6
ENSMUST00000081564.6
periostin, osteoblast specific factor
chr9_-_123678782 1.86 ENSMUST00000170591.1
ENSMUST00000171647.1
solute carrier family 6 (neurotransmitter transporter), member 20A
chr2_+_25372315 1.73 ENSMUST00000028329.6
ENSMUST00000114293.2
ENSMUST00000100323.2
suppressor APC domain containing 2
chr9_+_65890237 1.73 ENSMUST00000045802.6
RIKEN cDNA 2810417H13 gene
chr3_-_88410295 1.72 ENSMUST00000056370.7
polyamine-modulated factor 1
chr15_-_79285502 1.72 ENSMUST00000165408.1
BAI1-associated protein 2-like 2
chr3_-_49757257 1.70 ENSMUST00000035931.7
protocadherin 18
chr18_+_23415400 1.69 ENSMUST00000115832.2
ENSMUST00000047954.7
dystrobrevin alpha
chr3_+_68572245 1.65 ENSMUST00000170788.2
schwannomin interacting protein 1
chr12_+_38780284 1.64 ENSMUST00000162563.1
ENSMUST00000161164.1
ENSMUST00000160996.1
ets variant gene 1
chr16_-_45724600 1.62 ENSMUST00000096057.4
transgelin 3
chr9_-_70934808 1.59 ENSMUST00000034731.8
lipase, hepatic
chr1_+_139454747 1.56 ENSMUST00000053364.8
ENSMUST00000097554.3
asp (abnormal spindle)-like, microcephaly associated (Drosophila)
chr9_+_32116040 1.54 ENSMUST00000174641.1
Rho GTPase activating protein 32
chr4_+_150237694 1.48 ENSMUST00000141931.1
enolase 1, alpha non-neuron
chr12_+_38780817 1.36 ENSMUST00000160856.1
ets variant gene 1
chr9_-_123678873 1.35 ENSMUST00000040960.6
solute carrier family 6 (neurotransmitter transporter), member 20A
chr11_-_98053415 1.27 ENSMUST00000017544.2
SH3 and cysteine rich domain 2
chr16_-_63864114 1.26 ENSMUST00000064405.6
Eph receptor A3
chrX_-_102157065 1.15 ENSMUST00000056904.2
excision repair cross-complementing rodent repair deficiency complementation group 6 like
chr3_+_64081642 1.13 ENSMUST00000029406.4
vomeronasal 2, receptor 1
chr10_+_18469958 1.10 ENSMUST00000162891.1
ENSMUST00000100054.3
NHS-like 1
chrX_-_134111852 1.05 ENSMUST00000033610.6
NADPH oxidase 1
chr5_-_33433976 1.04 ENSMUST00000173348.1
NK1 transcription factor related, locus 1 (Drosophila)
chr6_+_71909046 1.01 ENSMUST00000055296.8
polymerase (RNA) I polypeptide A
chr3_+_94413244 0.97 ENSMUST00000166032.1
ENSMUST00000045245.5
tudor and KH domain containing protein
chr3_-_130730375 0.96 ENSMUST00000079085.6
ribosomal protein L34
chr7_+_35802593 0.94 ENSMUST00000052454.2
RIKEN cDNA E130304I02 gene
chr15_-_79285470 0.92 ENSMUST00000170955.1
BAI1-associated protein 2-like 2
chr5_+_120649188 0.87 ENSMUST00000156722.1
RAS protein activator like 1 (GAP1 like)
chr6_+_63255971 0.85 ENSMUST00000159561.1
ENSMUST00000095852.3
glutamate receptor, ionotropic, delta 2
chr19_-_55241236 0.83 ENSMUST00000069183.6
guanylate cyclase 2g
chrM_+_7759 0.83 ENSMUST00000082407.1
ENSMUST00000082408.1
mitochondrially encoded ATP synthase 8
mitochondrially encoded ATP synthase 6
chr2_-_5676046 0.82 ENSMUST00000114987.3
calcium/calmodulin-dependent protein kinase ID
chr5_-_62766153 0.82 ENSMUST00000076623.4
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr6_-_136781718 0.79 ENSMUST00000078095.6
ENSMUST00000032338.7
guanylate cyclase 2c
chrX_-_74246534 0.78 ENSMUST00000101454.2
ENSMUST00000033699.6
filamin, alpha
chr1_+_161494649 0.74 ENSMUST00000086084.1
tumor necrosis factor (ligand) superfamily, member 18
chr9_-_48911067 0.74 ENSMUST00000003826.7
5-hydroxytryptamine (serotonin) receptor 3A
chrX_+_153126897 0.74 ENSMUST00000163801.1
forkhead box R2
chr18_-_75697639 0.74 ENSMUST00000165559.1
CBP80/20-dependent translation initiation factor
chr14_-_47411666 0.73 ENSMUST00000111778.3
discs, large (Drosophila) homolog-associated protein 5
chr9_+_53771499 0.73 ENSMUST00000048670.8
solute carrier family 35, member F2
chrM_+_9452 0.73 ENSMUST00000082411.1
mitochondrially encoded NADH dehydrogenase 3
chr2_+_152754156 0.72 ENSMUST00000010020.5
cytochrome c oxidase subunit IV isoform 2
chr5_-_84417359 0.72 ENSMUST00000113401.1
Eph receptor A5
chr4_+_128993224 0.71 ENSMUST00000030583.6
ENSMUST00000102604.4
adenylate kinase 2
chr4_+_8690399 0.70 ENSMUST00000127476.1
chromodomain helicase DNA binding protein 7
chr7_-_116198487 0.68 ENSMUST00000181981.1
pleckstrin homology domain containing, family A member 7
chrX_+_49463926 0.67 ENSMUST00000130558.1
Rho GTPase activating protein 36
chr3_+_133338936 0.66 ENSMUST00000150386.1
ENSMUST00000125858.1
pyrophosphatase (inorganic) 2
chr3_+_94398517 0.64 ENSMUST00000050975.3
leucine rich repeat and Ig domain containing 4
chr7_+_64501687 0.62 ENSMUST00000032732.8
amyloid beta (A4) precursor protein-binding, family A, member 2
chr16_+_13358375 0.61 ENSMUST00000149359.1
MKL/myocardin-like 2
chr7_+_126776939 0.61 ENSMUST00000038614.5
ENSMUST00000170882.1
ENSMUST00000106359.1
ENSMUST00000106357.1
ENSMUST00000145762.1
ENSMUST00000132643.1
ENSMUST00000106356.1
yippee-like 3 (Drosophila)
chr15_-_101562889 0.60 ENSMUST00000023714.4
RIKEN cDNA 4732456N10 gene
chr17_+_49615104 0.60 ENSMUST00000162854.1
kinesin family member 6
chr6_+_134929118 0.60 ENSMUST00000185152.1
ENSMUST00000184504.1
RP23-45G16.5
chr6_+_8948608 0.58 ENSMUST00000160300.1
neurexophilin 1
chrX_-_162964557 0.57 ENSMUST00000038769.2
S100 calcium binding protein G
chr6_+_4755327 0.56 ENSMUST00000176551.1
paternally expressed 10
chr9_-_16378231 0.56 ENSMUST00000082170.5
FAT tumor suppressor homolog 3 (Drosophila)
chr12_+_117843873 0.55 ENSMUST00000176735.1
ENSMUST00000177339.1
cell division cycle associated 7 like
chr6_-_145047725 0.55 ENSMUST00000123930.1
branched chain aminotransferase 1, cytosolic
chr2_-_166155272 0.54 ENSMUST00000088086.3
sulfatase 2
chr1_-_183147461 0.54 ENSMUST00000171366.1
dispatched homolog 1 (Drosophila)
chr11_+_115307155 0.54 ENSMUST00000055490.2
otopetrin 2
chr18_+_4920509 0.53 ENSMUST00000126977.1
supervillin
chr7_-_45830776 0.52 ENSMUST00000107723.2
ENSMUST00000131384.1
glutamate-rich WD repeat containing 1
chr12_+_117843489 0.52 ENSMUST00000021592.9
cell division cycle associated 7 like
chr9_+_72806874 0.52 ENSMUST00000055535.8
protogenin homolog (Gallus gallus)
chr6_+_145934113 0.52 ENSMUST00000032383.7
sarcospan
chr8_-_31918203 0.51 ENSMUST00000073884.4
neuregulin 1
chr4_+_119637704 0.51 ENSMUST00000024015.2
guanylate cyclase activator 2a (guanylin)
chr1_+_40515362 0.51 ENSMUST00000027237.5
interleukin 18 receptor accessory protein
chr11_+_115334731 0.51 ENSMUST00000106543.1
ENSMUST00000019006.4
otopetrin 3
chr2_-_144527341 0.51 ENSMUST00000163701.1
ENSMUST00000081982.5
double zinc ribbon and ankyrin repeat domains 1
chr16_-_37384915 0.51 ENSMUST00000114787.1
ENSMUST00000114782.1
ENSMUST00000023526.2
ENSMUST00000114775.1
syntaxin binding protein 5-like
chr2_-_166155624 0.51 ENSMUST00000109249.2
sulfatase 2
chrX_-_157415286 0.50 ENSMUST00000079945.4
ENSMUST00000138396.1
phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets)
chr17_+_34039437 0.49 ENSMUST00000131134.1
ENSMUST00000087497.4
ENSMUST00000114255.1
ENSMUST00000114252.1
collagen, type XI, alpha 2
chr5_-_20882072 0.49 ENSMUST00000118174.1
putative homeodomain transcription factor 2
chr2_-_17460610 0.48 ENSMUST00000145492.1
nebulette
chr12_+_38781093 0.48 ENSMUST00000161513.1
ets variant gene 1
chr5_-_150518164 0.48 ENSMUST00000118769.1
zygote arrest 1-like
chr4_-_109665249 0.48 ENSMUST00000063531.4
cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
chr1_-_134955847 0.48 ENSMUST00000168381.1
protein phosphatase 1, regulatory (inhibitor) subunit 12B
chr16_-_37384940 0.48 ENSMUST00000114781.1
ENSMUST00000114780.1
syntaxin binding protein 5-like
chr3_+_103832741 0.48 ENSMUST00000106822.1
BCLl2-like 15
chr2_-_79456750 0.47 ENSMUST00000041099.4
neurogenic differentiation 1
chr11_+_23306910 0.47 ENSMUST00000137823.1
ubiquitin specific peptidase 34
chr15_+_55307743 0.47 ENSMUST00000023053.5
ENSMUST00000110221.2
ENSMUST00000110217.3
collagen, type XIV, alpha 1
chr11_+_116843278 0.47 ENSMUST00000106370.3
methyltransferase like 23
chr4_-_43499608 0.47 ENSMUST00000136005.1
ENSMUST00000054538.6
Rho guanine nucleotide exchange factor (GEF) 39
chr7_+_30493622 0.46 ENSMUST00000058280.6
ENSMUST00000133318.1
ENSMUST00000142575.1
ENSMUST00000131040.1
proline dehydrogenase (oxidase) 2
chr13_+_44729535 0.46 ENSMUST00000174068.1
jumonji, AT rich interactive domain 2
chrM_+_7005 0.46 ENSMUST00000082405.1
mitochondrially encoded cytochrome c oxidase II
chr8_+_121116163 0.46 ENSMUST00000054691.6
forkhead box C2
chr2_+_116067213 0.45 ENSMUST00000152412.1
RIKEN cDNA G630016G05 gene
chr19_+_44992127 0.45 ENSMUST00000179305.1
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chr9_+_113812547 0.45 ENSMUST00000166734.2
ENSMUST00000111838.2
ENSMUST00000163895.2
CLIP associating protein 2
chr6_-_50654438 0.45 ENSMUST00000031853.7
neuropeptide VF precursor
chr2_-_33086366 0.44 ENSMUST00000049618.2
GTPase activating RANGAP domain-like 3
chr6_+_34746368 0.44 ENSMUST00000142716.1
caldesmon 1
chr5_-_90640464 0.43 ENSMUST00000031317.6
Ras association (RalGDS/AF-6) domain family member 6
chr12_-_54986363 0.43 ENSMUST00000173433.1
ENSMUST00000173803.1
bromodomain adjacent to zinc finger domain 1A
predicted gene 20403
chr6_-_145047636 0.43 ENSMUST00000149769.1
branched chain aminotransferase 1, cytosolic
chrM_+_8600 0.43 ENSMUST00000082409.1
mitochondrially encoded cytochrome c oxidase III
chr2_+_125068118 0.43 ENSMUST00000070353.3
solute carrier family 24, member 5
chr14_-_68533689 0.43 ENSMUST00000022640.7
a disintegrin and metallopeptidase domain 7
chr12_+_108605757 0.42 ENSMUST00000109854.2
Ena-vasodilator stimulated phosphoprotein
chr2_+_119047129 0.41 ENSMUST00000153300.1
ENSMUST00000028799.5
cancer susceptibility candidate 5
chr9_-_15357692 0.41 ENSMUST00000098979.3
ENSMUST00000161132.1
RIKEN cDNA 5830418K08 gene
chr5_-_138171248 0.41 ENSMUST00000153867.1
minichromosome maintenance deficient 7 (S. cerevisiae)
chrM_+_2743 0.40 ENSMUST00000082392.1
mitochondrially encoded NADH dehydrogenase 1
chr3_-_130730310 0.40 ENSMUST00000062601.7
ribosomal protein L34
chr1_-_155417394 0.40 ENSMUST00000111775.1
ENSMUST00000111774.1
xenotropic and polytropic retrovirus receptor 1
chr11_+_76243715 0.40 ENSMUST00000040577.4
RNA methyltransferase like 1
chr10_+_127420867 0.40 ENSMUST00000064793.6
R3H domain containing 2
chr10_-_7212222 0.40 ENSMUST00000015346.5
Cnksr family member 3
chr3_+_103832562 0.39 ENSMUST00000062945.5
BCLl2-like 15
chr8_-_122460666 0.39 ENSMUST00000006762.5
snail homolog 3 (Drosophila)
chr4_+_48585135 0.39 ENSMUST00000030032.6
transmembrane protein with EGF-like and two follistatin-like domains 1
chr6_-_50456085 0.39 ENSMUST00000146341.1
ENSMUST00000071728.4
oxysterol binding protein-like 3
chr5_+_104202609 0.39 ENSMUST00000066708.5
dentin matrix protein 1
chr11_+_23306884 0.39 ENSMUST00000180046.1
ubiquitin specific peptidase 34
chrX_+_150547375 0.38 ENSMUST00000066337.6
ENSMUST00000112715.1
aminolevulinic acid synthase 2, erythroid
chr6_-_102464667 0.38 ENSMUST00000032159.6
contactin 3
chr13_+_23544052 0.38 ENSMUST00000075558.2
histone cluster 1, H3f
chr16_+_22918378 0.37 ENSMUST00000170805.1
fetuin beta
chr10_+_127421208 0.37 ENSMUST00000168780.1
R3H domain containing 2
chr7_-_102759465 0.37 ENSMUST00000168007.1
ENSMUST00000060187.7
olfactory receptor 78
chr1_+_53061637 0.37 ENSMUST00000027269.5
myostatin
chr9_-_55919605 0.37 ENSMUST00000037408.8
S phase cyclin A-associated protein in the ER
chr5_-_138170992 0.36 ENSMUST00000139983.1
minichromosome maintenance deficient 7 (S. cerevisiae)
chr4_+_48585193 0.36 ENSMUST00000107703.1
transmembrane protein with EGF-like and two follistatin-like domains 1
chr17_-_48432723 0.36 ENSMUST00000046549.3
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 2
chr11_+_58171648 0.36 ENSMUST00000020820.1
mitochondrial ribosomal protein L22
chrX_-_150814265 0.36 ENSMUST00000026302.6
ENSMUST00000129768.1
ENSMUST00000112699.2
melanoma antigen, family D, 2
chrX_+_153139941 0.35 ENSMUST00000039720.4
ENSMUST00000144175.2
Ras-related GTP binding B
chr11_-_77188968 0.35 ENSMUST00000108400.1
EF-hand calcium binding domain 5
chrX_+_166170449 0.35 ENSMUST00000130880.2
ENSMUST00000056410.4
ENSMUST00000096252.3
ENSMUST00000087169.4
gem (nuclear organelle) associated protein 8
chr1_-_152625212 0.34 ENSMUST00000027760.7
ral guanine nucleotide dissociation stimulator,-like 1
chr3_+_55782500 0.34 ENSMUST00000075422.4
mab-21-like 1 (C. elegans)
chr2_+_69897255 0.34 ENSMUST00000131553.1
ubiquitin protein ligase E3 component n-recognin 3
chr17_+_71019548 0.34 ENSMUST00000073211.5
ENSMUST00000179759.1
myomesin 1
chr2_+_162987330 0.34 ENSMUST00000018012.7
serum/glucocorticoid regulated kinase 2
chr2_+_162987502 0.34 ENSMUST00000117123.1
serum/glucocorticoid regulated kinase 2
chr13_-_58354862 0.34 ENSMUST00000043605.5
kinesin family member 27
chr4_-_126201117 0.33 ENSMUST00000136157.1
thyroid hormone receptor associated protein 3
chr2_-_45117349 0.33 ENSMUST00000176438.2
zinc finger E-box binding homeobox 2
chr11_-_87359011 0.33 ENSMUST00000055438.4
protein phosphatase 1E (PP2C domain containing)
chr7_-_126160992 0.33 ENSMUST00000164741.1
exportin 6
chr5_+_33658123 0.33 ENSMUST00000074849.6
ENSMUST00000079534.4
transforming, acidic coiled-coil containing protein 3
chr16_-_58524185 0.33 ENSMUST00000114357.3
ST3 beta-galactoside alpha-2,3-sialyltransferase 6
chr16_-_58524239 0.33 ENSMUST00000114358.2
ST3 beta-galactoside alpha-2,3-sialyltransferase 6
chrX_+_97072596 0.32 ENSMUST00000033556.3
G protein-coupled receptor 15-like
chr2_-_64975762 0.32 ENSMUST00000156765.1
growth factor receptor bound protein 14
chr19_+_23723279 0.32 ENSMUST00000067077.1
predicted gene 9938
chr10_+_85386813 0.32 ENSMUST00000105307.1
ENSMUST00000020231.3
BTB (POZ) domain containing 11
chr17_+_71019503 0.32 ENSMUST00000024847.7
myomesin 1
chr5_-_138171216 0.31 ENSMUST00000147920.1
minichromosome maintenance deficient 7 (S. cerevisiae)
chr7_-_126776818 0.31 ENSMUST00000068836.4
predicted gene 9967
chr5_-_66514815 0.31 ENSMUST00000161879.1
ENSMUST00000159357.1
amyloid beta (A4) precursor protein-binding, family B, member 2
chr8_-_95306585 0.31 ENSMUST00000119870.2
ENSMUST00000093268.4
cyclic nucleotide gated channel beta 1
chr9_-_20959785 0.31 ENSMUST00000177754.1
DNA methyltransferase (cytosine-5) 1
chr1_-_75046639 0.31 ENSMUST00000152855.1
nonhomologous end-joining factor 1
chr3_+_68869563 0.31 ENSMUST00000054551.2
RIKEN cDNA 1110032F04 gene
chr4_+_108719649 0.30 ENSMUST00000178992.1
RIKEN cDNA 3110021N24 gene
chr18_+_24603952 0.30 ENSMUST00000025120.6
elongator acetyltransferase complex subunit 2
chr7_+_64502090 0.30 ENSMUST00000137732.1
amyloid beta (A4) precursor protein-binding, family A, member 2
chr11_+_75532099 0.30 ENSMUST00000169547.2
solute carrier family 43, member 2
chr15_+_98167806 0.30 ENSMUST00000031914.4
expressed sequence AI836003
chr13_-_103764502 0.30 ENSMUST00000074616.5
splicing regulatory glutamine/lysine-rich protein 1
chr4_+_154960915 0.29 ENSMUST00000049621.6
hairy and enhancer of split 5 (Drosophila)
chr14_+_67745229 0.29 ENSMUST00000111095.2
gonadotropin releasing hormone 1
chr3_-_123236134 0.29 ENSMUST00000106427.1
ENSMUST00000106426.1
ENSMUST00000051443.5
synaptopodin 2
chr7_+_103550368 0.29 ENSMUST00000106888.1
olfactory receptor 613
chr3_+_115888139 0.29 ENSMUST00000106505.1
ENSMUST00000043342.9
DPH5 homolog (S. cerevisiae)
chr4_-_96785186 0.29 ENSMUST00000107071.1
predicted gene 12695
chr8_-_120228221 0.28 ENSMUST00000183235.1
RIKEN cDNA A330074K22 gene
chr12_-_55014329 0.28 ENSMUST00000172875.1
bromodomain adjacent to zinc finger domain 1A
chr8_-_84662841 0.28 ENSMUST00000060427.4
immediate early response 2
chr9_-_103222063 0.28 ENSMUST00000170904.1
transferrin
chr4_+_59035088 0.28 ENSMUST00000041160.6
guanine nucleotide binding protein (G protein), gamma 10
chr8_+_85432686 0.28 ENSMUST00000180883.1
RIKEN cDNA 1700051O22 Gene
chr3_+_62419668 0.28 ENSMUST00000161057.1
Rho guanine nucleotide exchange factor (GEF) 26
chr1_-_144545320 0.28 ENSMUST00000184189.1
regulator of G-protein signalling 21
chr2_-_73453918 0.28 ENSMUST00000102679.1
WAS/WASL interacting protein family, member 1
chr2_+_36230426 0.27 ENSMUST00000062069.5
prostaglandin-endoperoxide synthase 1
chr3_-_116253467 0.27 ENSMUST00000090473.5
G-protein coupled receptor 88
chr12_+_71170589 0.27 ENSMUST00000129376.1
RIKEN cDNA 2700049A03 gene
chr2_+_68104671 0.26 ENSMUST00000042456.3
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr4_+_13743424 0.26 ENSMUST00000006761.3
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr7_+_43781054 0.26 ENSMUST00000014058.9
kallikrein related-peptidase 10
chr10_-_28986280 0.26 ENSMUST00000152363.1
ENSMUST00000015663.6
RIKEN cDNA 2310057J18 gene
chr2_-_71055534 0.26 ENSMUST00000090849.5
ENSMUST00000100037.2
ENSMUST00000112186.2
methyltransferase like 8

Network of associatons between targets according to the STRING database.

First level regulatory network of Nkx6-1_Evx1_Hesx1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.2 GO:0035524 proline transmembrane transport(GO:0035524)
0.6 1.9 GO:1904209 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.4 1.3 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
0.3 1.6 GO:0051661 maintenance of centrosome location(GO:0051661)
0.3 3.6 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.3 1.1 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.3 0.8 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.3 1.0 GO:0045726 positive regulation of integrin biosynthetic process(GO:0045726)
0.2 0.7 GO:2000328 regulation of T-helper 17 cell lineage commitment(GO:2000328)
0.2 0.5 GO:1902256 apoptotic process involved in outflow tract morphogenesis(GO:0003275) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256)
0.2 1.6 GO:0034372 very-low-density lipoprotein particle remodeling(GO:0034372)
0.2 0.7 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.2 1.0 GO:1904749 regulation of protein localization to nucleolus(GO:1904749)
0.2 1.0 GO:0009082 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.2 0.5 GO:0002940 tRNA N2-guanine methylation(GO:0002940)
0.2 0.5 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.1 0.6 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 0.1 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.1 0.4 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.1 0.4 GO:1900135 positive regulation of renin secretion into blood stream(GO:1900135)
0.1 1.1 GO:0097475 motor neuron migration(GO:0097475)
0.1 0.8 GO:1904861 excitatory synapse assembly(GO:1904861)
0.1 0.7 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.1 0.7 GO:0006172 ADP biosynthetic process(GO:0006172)
0.1 2.6 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.1 0.7 GO:0045218 zonula adherens maintenance(GO:0045218)
0.1 2.1 GO:0045332 phospholipid translocation(GO:0045332)
0.1 0.3 GO:0060488 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.1 1.1 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 0.4 GO:1900377 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.1 0.3 GO:1903537 meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
0.1 0.5 GO:0060023 soft palate development(GO:0060023)
0.1 0.3 GO:2000978 negative regulation of forebrain neuron differentiation(GO:2000978)
0.1 1.5 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.1 0.5 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.1 0.4 GO:0014732 skeletal muscle atrophy(GO:0014732)
0.1 0.3 GO:0035633 maintenance of blood-brain barrier(GO:0035633)
0.1 0.3 GO:0061743 motor learning(GO:0061743)
0.1 0.6 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.1 0.3 GO:0044029 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.1 0.3 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.1 1.0 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 0.5 GO:0045213 neurotransmitter receptor metabolic process(GO:0045213)
0.1 0.3 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.1 0.2 GO:0036292 DNA rewinding(GO:0036292)
0.1 0.2 GO:1904579 response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579)
0.1 1.6 GO:0001553 luteinization(GO:0001553)
0.1 0.4 GO:1903690 positive regulation of extracellular matrix disassembly(GO:0090091) negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.1 0.4 GO:0032277 negative regulation of gonadotropin secretion(GO:0032277)
0.1 0.2 GO:0070904 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.1 0.4 GO:0070294 renal sodium ion absorption(GO:0070294)
0.1 0.3 GO:0033087 negative regulation of immature T cell proliferation(GO:0033087)
0.1 0.3 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.1 0.3 GO:0038032 termination of G-protein coupled receptor signaling pathway(GO:0038032)
0.1 1.3 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 0.2 GO:0090425 hepatocyte cell migration(GO:0002194) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.1 0.9 GO:0019236 response to pheromone(GO:0019236)
0.1 0.1 GO:0009441 glycolate metabolic process(GO:0009441)
0.1 1.0 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.1 GO:0001807 regulation of type IV hypersensitivity(GO:0001807) negative regulation of hypersensitivity(GO:0002884)
0.0 0.7 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.2 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.2 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.0 0.2 GO:0042360 vitamin E metabolic process(GO:0042360)
0.0 0.5 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 0.3 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.0 0.3 GO:0070447 positive regulation of oligodendrocyte progenitor proliferation(GO:0070447)
0.0 0.2 GO:0010749 regulation of nitric oxide mediated signal transduction(GO:0010749)
0.0 0.1 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.0 0.3 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.0 0.3 GO:0045217 cell-cell junction maintenance(GO:0045217)
0.0 0.4 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.0 0.5 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 0.9 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.0 0.1 GO:2000722 regulation of phenotypic switching(GO:1900239) negative regulation of vascular associated smooth muscle cell migration(GO:1904753) regulation of cardiac vascular smooth muscle cell differentiation(GO:2000722) positive regulation of cardiac vascular smooth muscle cell differentiation(GO:2000724)
0.0 1.6 GO:0006182 cGMP biosynthetic process(GO:0006182)
0.0 1.0 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.2 GO:0033762 response to glucagon(GO:0033762)
0.0 0.5 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.5 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.1 GO:0045950 negative regulation of mitotic recombination(GO:0045950)
0.0 0.2 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0 0.2 GO:0035356 cellular triglyceride homeostasis(GO:0035356)
0.0 0.1 GO:2000317 CD4-positive, CD25-positive, alpha-beta regulatory T cell lineage commitment(GO:0002362) negative regulation of histone deacetylation(GO:0031064) positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032831) negative regulation of interferon-gamma biosynthetic process(GO:0045077) negative regulation of T-helper 17 type immune response(GO:2000317) negative regulation of T-helper 17 cell differentiation(GO:2000320)
0.0 0.3 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.2 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.9 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.4 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.0 0.2 GO:0043545 molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0 0.2 GO:0003105 negative regulation of glomerular filtration(GO:0003105)
0.0 0.5 GO:0080111 DNA demethylation(GO:0080111)
0.0 0.3 GO:0080009 mRNA methylation(GO:0080009)
0.0 0.2 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.0 1.1 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.0 0.1 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 0.5 GO:0060539 diaphragm development(GO:0060539)
0.0 0.3 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 0.1 GO:1900170 negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
0.0 0.1 GO:0036324 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324)
0.0 0.1 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.0 0.1 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0 0.2 GO:1902259 regulation of delayed rectifier potassium channel activity(GO:1902259)
0.0 0.2 GO:0042297 vocal learning(GO:0042297) imitative learning(GO:0098596)
0.0 0.8 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.1 GO:0009946 proximal/distal axis specification(GO:0009946)
0.0 0.2 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.0 0.3 GO:0030953 astral microtubule organization(GO:0030953)
0.0 0.1 GO:0031161 phosphatidylinositol catabolic process(GO:0031161)
0.0 0.1 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.0 0.5 GO:2000651 positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.0 0.4 GO:0022904 respiratory electron transport chain(GO:0022904)
0.0 0.7 GO:0071384 cellular response to corticosteroid stimulus(GO:0071384) cellular response to glucocorticoid stimulus(GO:0071385)
0.0 0.0 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.0 0.1 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
0.0 0.1 GO:0090472 dibasic protein processing(GO:0090472)
0.0 0.1 GO:0032202 telomere assembly(GO:0032202)
0.0 0.3 GO:1901016 regulation of potassium ion transmembrane transporter activity(GO:1901016)
0.0 0.1 GO:0060382 release from viral latency(GO:0019046) regulation of DNA strand elongation(GO:0060382)
0.0 0.1 GO:1900045 negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915)
0.0 0.1 GO:0007113 endomitotic cell cycle(GO:0007113)
0.0 0.3 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.1 GO:0032685 negative regulation of granulocyte macrophage colony-stimulating factor production(GO:0032685)
0.0 0.1 GO:0030311 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 0.4 GO:0033194 response to hydroperoxide(GO:0033194)
0.0 0.5 GO:0061050 regulation of cell growth involved in cardiac muscle cell development(GO:0061050)
0.0 0.1 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.0 0.1 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.1 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0 0.2 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.1 GO:1901844 regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844)
0.0 0.1 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 0.2 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.4 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 0.0 GO:2000583 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790) regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584)
0.0 0.3 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.1 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.1 GO:0030035 microspike assembly(GO:0030035)
0.0 1.2 GO:0032411 positive regulation of transporter activity(GO:0032411)
0.0 0.3 GO:0003351 epithelial cilium movement(GO:0003351)
0.0 0.3 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.2 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.2 GO:2000671 regulation of motor neuron apoptotic process(GO:2000671)
0.0 0.0 GO:0035425 autocrine signaling(GO:0035425)
0.0 0.1 GO:0033078 extrathymic T cell differentiation(GO:0033078)
0.0 0.2 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.1 GO:0043497 regulation of protein heterodimerization activity(GO:0043497)
0.0 0.1 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.1 GO:0060744 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.0 0.4 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.1 GO:0071421 manganese ion transmembrane transport(GO:0071421)
0.0 0.3 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.1 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.6 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512)
0.0 0.1 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.3 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.0 0.2 GO:0097435 fibril organization(GO:0097435)
0.0 0.0 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.0 0.4 GO:2000171 negative regulation of dendrite development(GO:2000171)
0.0 0.1 GO:0061739 protein lipidation involved in autophagosome assembly(GO:0061739)
0.0 0.5 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 1.7 GO:0051099 positive regulation of binding(GO:0051099)
0.0 0.1 GO:0035095 behavioral response to nicotine(GO:0035095)
0.0 2.3 GO:0007519 skeletal muscle tissue development(GO:0007519)
0.0 0.1 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.6 GO:0015807 L-amino acid transport(GO:0015807)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.6 GO:0036449 microtubule minus-end(GO:0036449)
0.3 1.7 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.2 2.6 GO:0071439 clathrin complex(GO:0071439)
0.2 0.8 GO:0031523 Myb complex(GO:0031523)
0.2 1.0 GO:0071547 piP-body(GO:0071547)
0.2 1.7 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.2 0.7 GO:0008623 CHRAC(GO:0008623)
0.1 0.4 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.1 0.7 GO:0097226 sperm mitochondrial sheath(GO:0097226)
0.1 1.0 GO:0071438 invadopodium membrane(GO:0071438)
0.1 0.3 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.1 0.3 GO:0060187 cell pole(GO:0060187)
0.1 1.7 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 1.4 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 1.1 GO:0042555 MCM complex(GO:0042555)
0.1 0.4 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 3.0 GO:0043034 costamere(GO:0043034)
0.1 0.7 GO:0005915 zonula adherens(GO:0005915)
0.1 1.0 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1 0.3 GO:1990696 USH2 complex(GO:1990696)
0.1 1.6 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 0.8 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 1.5 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 0.3 GO:0032807 DNA ligase IV complex(GO:0032807)
0.0 0.4 GO:0030478 actin cap(GO:0030478)
0.0 0.8 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.3 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.7 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.5 GO:0032797 SMN complex(GO:0032797)
0.0 0.3 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 0.7 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.3 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 1.5 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.6 GO:0005859 muscle myosin complex(GO:0005859)
0.0 2.6 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.1 GO:0042585 germinal vesicle(GO:0042585)
0.0 0.7 GO:0070469 respiratory chain(GO:0070469)
0.0 0.1 GO:0000125 PCAF complex(GO:0000125)
0.0 0.1 GO:1990047 spindle matrix(GO:1990047)
0.0 0.8 GO:0031672 A band(GO:0031672)
0.0 0.3 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.1 GO:1903439 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.0 0.2 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 1.6 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.2 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.3 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.1 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0 2.9 GO:0001650 fibrillar center(GO:0001650)
0.0 0.1 GO:0070652 HAUS complex(GO:0070652)
0.0 0.2 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.1 GO:0071437 invadopodium(GO:0071437)
0.0 0.4 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.1 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.4 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.2 GO:0036038 MKS complex(GO:0036038)
0.0 0.1 GO:0072487 MSL complex(GO:0072487)
0.0 0.3 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.2 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.1 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.2 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.1 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.1 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.0 0.9 GO:0098878 ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.0 0.4 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.3 GO:0035267 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.2 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.3 1.6 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.2 2.0 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.2 1.1 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.2 1.0 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.2 1.7 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.2 0.7 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.2 0.7 GO:0052798 beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798)
0.2 1.0 GO:0052654 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.2 0.8 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.1 0.5 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 0.4 GO:0016748 succinyltransferase activity(GO:0016748)
0.1 0.5 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.1 1.7 GO:0043522 leucine zipper domain binding(GO:0043522)
0.1 0.4 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.1 0.5 GO:0030250 cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.1 0.5 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.1 0.6 GO:0005499 vitamin D binding(GO:0005499)
0.1 2.0 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 0.2 GO:0001147 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160) 5'-3' exoribonuclease activity(GO:0004534)
0.1 0.2 GO:0008431 vitamin E binding(GO:0008431)
0.1 2.1 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 1.0 GO:0001054 RNA polymerase I activity(GO:0001054)
0.1 0.1 GO:1902121 lithocholic acid binding(GO:1902121)
0.1 0.3 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.1 1.9 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 0.3 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 0.2 GO:0070890 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.1 1.6 GO:0004383 guanylate cyclase activity(GO:0004383)
0.1 0.8 GO:0051378 serotonin binding(GO:0051378)
0.1 0.4 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 0.7 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 0.2 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.1 0.3 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1 0.5 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.1 0.7 GO:0070097 delta-catenin binding(GO:0070097)
0.1 0.2 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.1 0.7 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.1 GO:0042015 interleukin-20 binding(GO:0042015)
0.0 0.1 GO:0008311 double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.0 0.3 GO:0072510 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.0 0.3 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.2 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 0.2 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.5 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.3 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.2 GO:0048101 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.2 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.9 GO:0005234 extracellular-glutamate-gated ion channel activity(GO:0005234)
0.0 0.2 GO:0032407 MutSalpha complex binding(GO:0032407)
0.0 0.4 GO:0005522 profilin binding(GO:0005522)
0.0 1.2 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.2 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.0 0.2 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 0.2 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.4 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.7 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.1 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.0 0.2 GO:0036310 annealing helicase activity(GO:0036310)
0.0 1.1 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 1.9 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.1 GO:0038049 glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.1 GO:0043532 angiostatin binding(GO:0043532)
0.0 0.1 GO:0019770 IgG receptor activity(GO:0019770)
0.0 0.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.2 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.3 GO:0052813 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 1.3 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.1 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0 0.9 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.2 GO:0001851 complement component C3b binding(GO:0001851)
0.0 0.1 GO:0097643 amylin receptor activity(GO:0097643)
0.0 0.2 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.3 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.0 0.0 GO:0004948 calcitonin receptor activity(GO:0004948)
0.0 0.2 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.1 GO:0031493 nucleosomal histone binding(GO:0031493)
0.0 0.1 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.8 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.1 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.0 0.1 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.0 0.2 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 0.1 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.2 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.2 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.1 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.0 0.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.1 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.6 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 0.1 GO:0019865 immunoglobulin binding(GO:0019865)
0.0 0.1 GO:0042328 heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328)
0.0 0.2 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 0.6 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.7 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.1 GO:0051381 histamine binding(GO:0051381)
0.0 0.1 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.2 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.1 GO:0031013 troponin I binding(GO:0031013)
0.0 0.1 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 0.7 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.2 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.2 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.1 GO:0008934 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.0 0.3 GO:0031005 filamin binding(GO:0031005)
0.0 0.1 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 2.5 GO:0051015 actin filament binding(GO:0051015)
0.0 0.0 GO:0008534 oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534)
0.0 1.9 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.8 GO:0019905 syntaxin binding(GO:0019905)
0.0 0.2 GO:0051400 BH domain binding(GO:0051400)
0.0 1.0 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.2 GO:0008143 poly(A) binding(GO:0008143)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.5 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 2.0 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 3.3 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 1.3 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.3 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 0.6 PID ARF6 PATHWAY Arf6 signaling events
0.0 3.2 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.9 PID AURORA A PATHWAY Aurora A signaling
0.0 0.9 ST GA12 PATHWAY G alpha 12 Pathway
0.0 1.9 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 1.1 PID ATR PATHWAY ATR signaling pathway
0.0 0.6 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.9 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.1 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.3 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 1.0 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.5 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.0 PID S1P S1P3 PATHWAY S1P3 pathway
0.0 0.1 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.8 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.3 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 1.9 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 1.1 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.1 2.0 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.1 0.2 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 1.0 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 1.7 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 1.0 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 3.7 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.7 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.7 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.7 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 0.5 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.6 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.2 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.5 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.4 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.2 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 2.0 REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION Genes involved in 3' -UTR-mediated translational regulation
0.0 0.7 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.4 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.3 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.2 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.1 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.5 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.2 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.2 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.4 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.2 REACTOME KINESINS Genes involved in Kinesins
0.0 0.1 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.2 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.1 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER