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12D miR HR13_24

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Results for Nr6a1

Z-value: 0.54

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Transcription factors associated with Nr6a1

Gene Symbol Gene ID Gene Info
ENSMUSG00000063972.7 nuclear receptor subfamily 6, group A, member 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nr6a1mm10_v2_chr2_-_38926217_38926454-0.731.1e-02Click!

Activity profile of Nr6a1 motif

Sorted Z-values of Nr6a1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr9_+_53301571 0.99 ENSMUST00000051014.1
exophilin 5
chr14_+_58072686 0.90 ENSMUST00000022545.7
fibroblast growth factor 9
chr7_-_66427469 0.81 ENSMUST00000015278.7
aldehyde dehydrogenase family 1, subfamily A3
chr5_-_5694559 0.77 ENSMUST00000115426.2
six transmembrane epithelial antigen of prostate 2
chr16_+_17276337 0.73 ENSMUST00000159065.1
ENSMUST00000159494.1
ENSMUST00000159811.1
transmembrane protein 191C
chr5_-_5694024 0.69 ENSMUST00000115425.2
ENSMUST00000115427.1
ENSMUST00000115424.2
ENSMUST00000015797.4
six transmembrane epithelial antigen of prostate 2
chr16_+_17276291 0.68 ENSMUST00000164950.1
ENSMUST00000159242.1
transmembrane protein 191C
chr10_-_68541842 0.66 ENSMUST00000020103.2
RIKEN cDNA 1700040L02 gene
chr9_+_87144285 0.63 ENSMUST00000113149.1
ENSMUST00000143779.1
ENSMUST00000179313.1
ENSMUST00000049457.7
ENSMUST00000153444.1
melanocortin 2 receptor accessory protein 2
chr5_-_5694269 0.62 ENSMUST00000148333.1
six transmembrane epithelial antigen of prostate 2
chr6_+_42245907 0.61 ENSMUST00000031897.5
glutathione S-transferase kappa 1
chr17_+_72918298 0.60 ENSMUST00000024857.6
limb-bud and heart
chr4_-_45530330 0.53 ENSMUST00000061986.5
src homology 2 domain-containing transforming protein B
chr5_-_108674753 0.37 ENSMUST00000119270.1
ENSMUST00000163328.1
ENSMUST00000136227.1
solute carrier family 26 (sulfate transporter), member 1
chr13_+_25056004 0.33 ENSMUST00000036932.8
doublecortin domain containing 2a
chr17_-_57228003 0.33 ENSMUST00000177046.1
ENSMUST00000024988.8
complement component 3
chr2_+_172472512 0.30 ENSMUST00000029007.2
family with sequence similarity 209
chr11_-_69822144 0.30 ENSMUST00000045771.6
sperm maturation 1
chr6_+_135198034 0.29 ENSMUST00000130612.1
RIKEN cDNA 8430419L09 gene
chr16_-_3718105 0.29 ENSMUST00000023180.7
ENSMUST00000100222.2
Mediterranean fever
chr9_-_96437434 0.28 ENSMUST00000070500.2
cDNA sequence BC043934
chr11_-_99244058 0.28 ENSMUST00000103132.3
ENSMUST00000038214.6
keratin 222
chr17_-_34804546 0.27 ENSMUST00000025223.8
cytochrome P450, family 21, subfamily a, polypeptide 1
chr15_-_58364148 0.27 ENSMUST00000068515.7
annexin A13
chr7_-_110769345 0.25 ENSMUST00000098108.2
RIKEN cDNA B430319F04 gene
chr5_+_114003678 0.25 ENSMUST00000112292.2
D-amino acid oxidase
chr17_+_29114142 0.24 ENSMUST00000141797.1
ENSMUST00000132262.1
ENSMUST00000141239.1
ENSMUST00000138816.1
predicted gene 16194
chr7_+_128265675 0.24 ENSMUST00000118169.1
ENSMUST00000142841.1
solute carrier family 5 (sodium/glucose cotransporter), member 2
chr5_-_136986829 0.23 ENSMUST00000034953.7
ENSMUST00000085941.5
zinc finger, HIT domain containing 1
chr6_+_83349446 0.22 ENSMUST00000136501.1
bolA-like 3 (E. coli)
chr5_+_114003833 0.22 ENSMUST00000086599.4
D-amino acid oxidase
chr15_+_31572179 0.22 ENSMUST00000161088.1
carboxymethylenebutenolidase-like (Pseudomonas)
chr2_+_157424255 0.19 ENSMUST00000029175.7
ENSMUST00000092576.4
Rous sarcoma oncogene
chr5_+_136987019 0.19 ENSMUST00000004968.4
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
chr1_+_160978576 0.17 ENSMUST00000064725.5
serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1
chr9_+_122805524 0.17 ENSMUST00000052740.7
T cell activation inhibitor, mitochondrial
chr11_+_6560183 0.16 ENSMUST00000109722.2
cerebral cavernous malformation 2
chr10_+_21978643 0.16 ENSMUST00000142174.1
ENSMUST00000164659.1
serum/glucocorticoid regulated kinase 1
chr6_+_135197977 0.16 ENSMUST00000111915.1
ENSMUST00000111916.1
RIKEN cDNA 8430419L09 gene
chr2_-_127729872 0.16 ENSMUST00000028856.2
mal, T cell differentiation protein-like
chr5_+_114175889 0.14 ENSMUST00000146841.1
acetyl-Coenzyme A carboxylase beta
chr9_+_50603892 0.14 ENSMUST00000044051.4
translocase of inner mitochondrial membrane 8B
chr4_+_43632185 0.14 ENSMUST00000107874.2
natriuretic peptide receptor 2
chr4_-_125065603 0.13 ENSMUST00000036383.3
dynein, axonemal, light intermediate polypeptide 1
chrX_-_36991724 0.13 ENSMUST00000152291.1
septin 6
chr16_+_10170216 0.12 ENSMUST00000121292.1
ribosomal protein L39-like
chr16_+_10170228 0.12 ENSMUST00000044103.5
ribosomal protein L39-like
chrX_-_8018492 0.12 ENSMUST00000033503.2
glyoxalase domain containing 5
chr2_+_127425155 0.12 ENSMUST00000062211.3
ENSMUST00000110373.1
glycerol-3-phosphate acyltransferase 2, mitochondrial
chr9_-_119157055 0.11 ENSMUST00000010795.4
acetyl-Coenzyme A acyltransferase 1B
chrX_-_60147643 0.11 ENSMUST00000033478.4
ENSMUST00000101531.3
mcf.2 transforming sequence
chr14_+_78849171 0.11 ENSMUST00000040990.5
von Willebrand factor A domain containing 8
chr17_+_33629078 0.10 ENSMUST00000166627.1
ENSMUST00000073570.5
ENSMUST00000170225.1
zinc finger protein 414
chr1_-_151428440 0.10 ENSMUST00000064771.5
SWT1 RNA endoribonuclease homolog (S. cerevisiae)
chr9_+_73101836 0.10 ENSMUST00000172578.1
KH domain containing 3, subcortical maternal complex member
chr7_-_130772652 0.10 ENSMUST00000057134.4
ectopic ossification 1
chr4_+_138434647 0.10 ENSMUST00000044058.4
ENSMUST00000105813.1
ENSMUST00000105815.1
mitochondrial ubiquitin ligase activator of NFKB 1
chr6_+_71293765 0.09 ENSMUST00000114185.2
predicted gene 1070
chr1_+_151428612 0.08 ENSMUST00000065625.5
tRNA methyltransferase 1 like
chr11_+_120677226 0.08 ENSMUST00000129644.2
ENSMUST00000151160.1
alveolar soft part sarcoma chromosome region, candidate 1 (human)
chr2_+_173737492 0.08 ENSMUST00000067530.4
vesicle-associated membrane protein, associated protein B and C
chr1_+_82724909 0.07 ENSMUST00000073025.5
ENSMUST00000161648.1
ENSMUST00000160786.1
ENSMUST00000162003.1
mitochondrial fission factor
chr15_-_98165613 0.07 ENSMUST00000143400.1
ankyrin repeat and SOCS box-containing 8
chr14_+_76488436 0.06 ENSMUST00000101618.2
TSC22 domain family, member 1
chr7_+_16944645 0.06 ENSMUST00000094807.5
PNMA-like 2
chr4_-_82505274 0.06 ENSMUST00000050872.8
ENSMUST00000064770.2
nuclear factor I/B
chr7_+_30314810 0.06 ENSMUST00000054594.8
ENSMUST00000177078.1
ENSMUST00000176504.1
ENSMUST00000176304.1
spectrin repeat containing, nuclear envelope family member 4
chr2_+_32606946 0.05 ENSMUST00000113290.1
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chr12_+_31390843 0.05 ENSMUST00000167432.1
solute carrier family 26, member 3
chr13_-_25020289 0.05 ENSMUST00000021772.2
MRS2 magnesium homeostasis factor homolog (S. cerevisiae)
chr4_-_139131058 0.05 ENSMUST00000143971.1
mitochondrial inner membrane organizing system 1
chr19_+_46707443 0.04 ENSMUST00000003655.7
arsenic (+3 oxidation state) methyltransferase
chr15_+_100038635 0.04 ENSMUST00000100203.3
DIP2 disco-interacting protein 2 homolog B (Drosophila)
chr9_-_121839460 0.04 ENSMUST00000135986.2
coiled-coil domain containing 13
chr18_+_64887690 0.04 ENSMUST00000163516.1
neural precursor cell expressed, developmentally down-regulated gene 4-like
chr6_-_129622685 0.04 ENSMUST00000032252.5
killer cell lectin-like receptor subfamily K, member 1
chr2_+_177768044 0.04 ENSMUST00000108942.3
predicted gene 14322
chr4_+_123201503 0.03 ENSMUST00000068262.5
5'-nucleotidase, cytosolic IA
chr2_+_32606979 0.02 ENSMUST00000113289.1
ENSMUST00000095044.3
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chr19_-_5688149 0.01 ENSMUST00000068169.5
pecanex-like 3 (Drosophila)
chr11_-_100770926 0.01 ENSMUST00000139341.1
ENSMUST00000017891.7
GH3 domain containing
chr1_+_171329015 0.01 ENSMUST00000111300.1
death effector domain-containing
chr3_-_96402010 0.01 ENSMUST00000181412.1
RIKEN cDNA 4930477E14 gene
chr11_-_76763550 0.01 ENSMUST00000010536.8
golgi SNAP receptor complex member 1
chr4_-_123904826 0.00 ENSMUST00000181292.1
predicted gene, 26606

Network of associatons between targets according to the STRING database.

First level regulatory network of Nr6a1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0060166 olfactory pit development(GO:0060166)
0.2 2.1 GO:0098706 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.2 1.0 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.2 0.5 GO:0036088 D-serine catabolic process(GO:0036088) D-alanine family amino acid metabolic process(GO:0046144) D-alanine metabolic process(GO:0046436) D-alanine catabolic process(GO:0055130)
0.1 0.6 GO:1904672 regulation of somatic stem cell population maintenance(GO:1904672)
0.1 0.3 GO:0071608 macrophage inflammatory protein-1 alpha production(GO:0071608)
0.1 0.7 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.1 0.3 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
0.1 0.4 GO:0019532 oxalate transport(GO:0019532)
0.1 0.9 GO:0060484 lung-associated mesenchyme development(GO:0060484)
0.0 0.1 GO:0046949 fatty-acyl-CoA biosynthetic process(GO:0046949) malonyl-CoA metabolic process(GO:2001293)
0.0 0.2 GO:0046946 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.0 0.2 GO:0051902 negative regulation of mitochondrial depolarization(GO:0051902)
0.0 0.2 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 0.2 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.0 0.1 GO:0071649 regulation of chemokine (C-C motif) ligand 5 production(GO:0071649)
0.0 0.1 GO:0044830 modulation by host of viral RNA genome replication(GO:0044830)
0.0 0.2 GO:1904659 glucose transmembrane transport(GO:1904659)
0.0 0.2 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.3 GO:0006705 mineralocorticoid biosynthetic process(GO:0006705)
0.0 0.0 GO:0002223 stimulatory C-type lectin receptor signaling pathway(GO:0002223)
0.0 0.1 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.0 0.2 GO:0060837 blood vessel endothelial cell differentiation(GO:0060837)
0.0 0.6 GO:0097009 energy homeostasis(GO:0097009)
0.0 0.2 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.1 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.1 GO:0005940 septin ring(GO:0005940)
0.0 0.3 GO:0060091 kinocilium(GO:0060091)
0.0 0.2 GO:0000812 Swr1 complex(GO:0000812)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.1 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.2 0.6 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
0.1 0.8 GO:0001758 retinal dehydrogenase activity(GO:0001758) 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.1 0.5 GO:0003884 D-amino-acid oxidase activity(GO:0003884)
0.0 0.2 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0 0.3 GO:1901611 phosphatidylglycerol binding(GO:1901611)
0.0 0.1 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.0 0.4 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.6 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 0.1 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.9 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.2 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.2 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 0.2 GO:0071253 connexin binding(GO:0071253)
0.0 0.1 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.0 0.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.5 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.5 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 1.1 PID FGF PATHWAY FGF signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.3 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.3 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.2 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.2 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins