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12D miR HR13_24

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Results for Mafb

Z-value: 1.12

Motif logo

Transcription factors associated with Mafb

Gene Symbol Gene ID Gene Info
ENSMUSG00000074622.3 v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Mafbmm10_v2_chr2_-_160367057_160367073-0.682.1e-02Click!

Activity profile of Mafb motif

Sorted Z-values of Mafb motif

Promoter Log-likelihood Transcript Gene Gene Info
chr9_-_96862903 1.86 ENSMUST00000121077.1
ENSMUST00000124923.1
acid phosphatase-like 2
chr11_-_31824518 1.55 ENSMUST00000134944.1
RIKEN cDNA D630024D03 gene
chr2_+_181219998 1.53 ENSMUST00000050026.6
ENSMUST00000108835.1
cDNA sequence BC051628
chr2_+_170731807 1.35 ENSMUST00000029075.4
docking protein 5
chr12_-_75177325 1.27 ENSMUST00000042299.2
potassium voltage-gated channel, subfamily H (eag-related), member 5
chr10_+_62920648 1.25 ENSMUST00000144459.1
solute carrier family 25 (mitochondrial carrier, Graves disease autoantigen), member 16
chr7_-_79793788 1.22 ENSMUST00000032760.5
mesoderm posterior 1
chr4_+_102421518 1.20 ENSMUST00000106904.2
phosphodiesterase 4B, cAMP specific
chr7_+_121083322 1.15 ENSMUST00000047025.8
ENSMUST00000170106.1
otoancorin
chr2_+_105130883 1.11 ENSMUST00000111098.1
ENSMUST00000111099.1
Wilms tumor 1 homolog
chr6_-_83033422 1.10 ENSMUST00000089651.5
docking protein 1
chr3_+_105870898 1.07 ENSMUST00000010279.5
adenosine A3 receptor
chr10_+_69212634 1.06 ENSMUST00000020101.5
Rho-related BTB domain containing 1
chr5_-_139819906 1.05 ENSMUST00000147328.1
transmembrane protein 184a
chr11_+_83709015 1.04 ENSMUST00000001009.7
WAP four-disulfide core domain 18
chr2_-_3419019 1.03 ENSMUST00000115084.1
ENSMUST00000115083.1
meiosis expressed gene 1
chr7_-_30861470 1.01 ENSMUST00000052700.3
free fatty acid receptor 1
chr7_-_100964371 0.95 ENSMUST00000060174.4
pyrimidinergic receptor P2Y, G-protein coupled, 6
chrX_+_101376359 0.94 ENSMUST00000119080.1
gap junction protein, beta 1
chr2_+_105126505 0.90 ENSMUST00000143043.1
Wilms tumor 1 homolog
chr10_+_26078255 0.90 ENSMUST00000041011.3
predicted gene 9767
chr10_-_53647080 0.89 ENSMUST00000169866.1
family with sequence similarity 184, member A
chr2_-_3419066 0.88 ENSMUST00000115082.3
meiosis expressed gene 1
chr4_+_41762309 0.88 ENSMUST00000108042.2
interleukin 11 receptor, alpha chain 1
chr5_+_140505550 0.87 ENSMUST00000043050.8
ENSMUST00000124142.1
carbohydrate sulfotransferase 12
chr11_+_106374820 0.87 ENSMUST00000106816.1
RIKEN cDNA 2310007L24 gene
chr8_-_85119637 0.86 ENSMUST00000098550.3
zinc finger protein 791
chr17_+_34398802 0.85 ENSMUST00000114175.1
ENSMUST00000078615.5
ENSMUST00000139063.1
ENSMUST00000097348.2
cDNA sequence BC051142
chr16_-_52452654 0.84 ENSMUST00000168071.1
activated leukocyte cell adhesion molecule
chr6_+_78405148 0.82 ENSMUST00000023906.2
regenerating islet-derived 2
chr4_+_143349757 0.79 ENSMUST00000052458.2
leucine rich repeat containing 38
chr7_+_140941550 0.78 ENSMUST00000079403.4
ATH1, acid trehalase-like 1 (yeast)
chr6_+_139736895 0.78 ENSMUST00000111868.3
phosphatidylinositol 3-kinase, C2 domain containing, gamma polypeptide
chr2_+_144556306 0.77 ENSMUST00000155876.1
ENSMUST00000149697.1
SEC23B (S. cerevisiae)
chr4_-_86669492 0.77 ENSMUST00000149700.1
perilipin 2
chr17_+_33920522 0.76 ENSMUST00000172489.1
TAP binding protein
chr4_+_141239499 0.76 ENSMUST00000141834.2
Rho guanine nucleotide exchange factor (GEF) 19
chr2_+_144556229 0.75 ENSMUST00000143573.1
ENSMUST00000028916.8
ENSMUST00000155258.1
SEC23B (S. cerevisiae)
chr17_+_31677924 0.73 ENSMUST00000019192.5
crystallin, alpha A
chr3_-_129332713 0.73 ENSMUST00000029658.7
glutamyl aminopeptidase
chr10_+_62920630 0.72 ENSMUST00000044977.3
solute carrier family 25 (mitochondrial carrier, Graves disease autoantigen), member 16
chr16_+_17331371 0.72 ENSMUST00000023450.6
ENSMUST00000161034.1
serine (or cysteine) peptidase inhibitor, clade D, member 1
chr11_+_115877497 0.71 ENSMUST00000144032.1
myosin XVB
chr14_+_77036746 0.71 ENSMUST00000048208.3
ENSMUST00000095625.4
coiled-coil domain containing 122
chr4_-_137118135 0.68 ENSMUST00000154285.1
predicted gene 13001
chr4_-_25281801 0.67 ENSMUST00000102994.3
UFM1 specific ligase 1
chr6_+_120773633 0.65 ENSMUST00000112682.2
solute carrier family 25 (mitochondrial carrier), member 18
chr11_+_71749914 0.65 ENSMUST00000150531.1
WSC domain containing 1
chr7_+_30184160 0.63 ENSMUST00000098594.2
cytochrome c oxidase subunit VIIa 1
chr19_-_5510467 0.62 ENSMUST00000070172.4
sorting nexin 32
chr4_+_138967112 0.62 ENSMUST00000116094.2
ring finger protein 186
chr12_+_76081645 0.61 ENSMUST00000154509.1
spectrin repeat containing, nuclear envelope 2
chr6_-_72390659 0.61 ENSMUST00000059983.9
vesicle-associated membrane protein 8
chr4_-_25281752 0.60 ENSMUST00000038705.7
UFM1 specific ligase 1
chr15_+_31224371 0.59 ENSMUST00000044524.9
death-associated protein
chr8_-_25091341 0.58 ENSMUST00000125466.1
pleckstrin homology domain-containing, family A (phosphoinositide binding specific) member 2
chr3_+_106113229 0.58 ENSMUST00000079132.5
ENSMUST00000139086.1
chitinase, acidic
chr2_-_66634653 0.58 ENSMUST00000164384.2
ENSMUST00000169900.1
sodium channel, voltage-gated, type IX, alpha
chr6_-_56369625 0.57 ENSMUST00000170774.1
ENSMUST00000168944.1
ENSMUST00000166890.1
phosphodiesterase 1C
chr7_-_110862944 0.56 ENSMUST00000033050.3
lymphatic vessel endothelial hyaluronan receptor 1
chr11_+_5520652 0.56 ENSMUST00000063084.9
X-box binding protein 1
chr4_+_98395768 0.55 ENSMUST00000041284.3
InaD-like (Drosophila)
chr3_-_59262825 0.55 ENSMUST00000050360.7
purinergic receptor P2Y, G-protein coupled 12
chr1_+_110099295 0.55 ENSMUST00000134301.1
cadherin 7, type 2
chr7_+_143475094 0.53 ENSMUST00000105917.2
solute carrier family 22 (organic cation transporter), member 18
chr5_+_141856692 0.53 ENSMUST00000074546.6
sidekick homolog 1 (chicken)
chr4_+_45012830 0.52 ENSMUST00000095105.1
RIKEN cDNA 1700055D18 gene
chr3_-_103737995 0.52 ENSMUST00000029440.8
olfactomedin-like 3
chr9_-_44320229 0.52 ENSMUST00000065080.8
C2 calcium-dependent domain containing 2-like
chr17_+_6270475 0.51 ENSMUST00000088940.4
transmembrane protein 181A
chr13_-_23710714 0.51 ENSMUST00000091707.6
ENSMUST00000006787.7
ENSMUST00000091706.6
hemochromatosis
chr3_+_105870858 0.50 ENSMUST00000164730.1
adenosine A3 receptor
chr11_+_119355551 0.50 ENSMUST00000050880.7
solute carrier family 26, member 11
chr12_-_98259416 0.50 ENSMUST00000021390.7
galactosylceramidase
chr7_+_128173944 0.49 ENSMUST00000033051.9
ENSMUST00000177111.1
integrin, alpha D
chr1_-_14918862 0.49 ENSMUST00000041447.4
transient receptor potential cation channel, subfamily A, member 1
chr17_-_17883920 0.48 ENSMUST00000061516.7
formyl peptide receptor 1
chr3_-_107986360 0.48 ENSMUST00000066530.6
glutathione S-transferase, mu 2
chr12_+_17266545 0.48 ENSMUST00000057288.5
protein disulfide isomerase associated 6
chr9_+_120577346 0.48 ENSMUST00000064646.4
RIKEN cDNA 5830454E08 gene
chr9_+_109931774 0.46 ENSMUST00000169851.2
microtubule-associated protein 4
chr11_+_50357759 0.46 ENSMUST00000052596.2
chibby homolog 3 (Drosophila)
chr16_-_36455378 0.45 ENSMUST00000068182.2
stefin A3
chr3_-_107986408 0.45 ENSMUST00000012348.2
glutathione S-transferase, mu 2
chr16_-_36990449 0.45 ENSMUST00000075869.6
F-box protein 40
chr4_+_98395891 0.45 ENSMUST00000107030.2
InaD-like (Drosophila)
chr4_+_98546919 0.45 ENSMUST00000030290.7
InaD-like (Drosophila)
chr18_-_38338997 0.44 ENSMUST00000063814.8
glucosamine-6-phosphate deaminase 1
chr3_+_41555723 0.44 ENSMUST00000026865.8
PHD finger protein 17
chr11_-_83592981 0.44 ENSMUST00000019071.3
chemokine (C-C motif) ligand 6
chr1_-_121327776 0.44 ENSMUST00000160688.1
insulin induced gene 2
chr13_-_62607499 0.44 ENSMUST00000091563.4
RIKEN cDNA 6720489N17 gene
chr4_+_98395817 0.44 ENSMUST00000107033.1
ENSMUST00000107034.1
InaD-like (Drosophila)
chr2_-_130397525 0.44 ENSMUST00000028897.7
carboxypeptidase X 1 (M14 family)
chr1_-_121327734 0.43 ENSMUST00000160968.1
ENSMUST00000162582.1
insulin induced gene 2
chr11_-_33578933 0.43 ENSMUST00000020366.1
ENSMUST00000135350.1
gamma-aminobutyric acid (GABA) A receptor, pi
chr18_-_38338909 0.43 ENSMUST00000139885.1
glucosamine-6-phosphate deaminase 1
chr6_-_137649211 0.43 ENSMUST00000134630.1
ENSMUST00000058210.6
ENSMUST00000111878.1
epidermal growth factor receptor pathway substrate 8
chr10_+_34297421 0.43 ENSMUST00000047935.6
TSPY-like 4
chr9_+_109931458 0.43 ENSMUST00000072772.5
ENSMUST00000035055.8
microtubule-associated protein 4
chr3_-_88372740 0.42 ENSMUST00000107543.1
ENSMUST00000107542.1
bone gamma-carboxyglutamate protein 3
chr6_+_41458923 0.42 ENSMUST00000031910.7
protease, serine, 1 (trypsin 1)
chr2_-_168741898 0.41 ENSMUST00000109176.1
ENSMUST00000178504.1
ATPase, class II, type 9A
chr9_-_21239310 0.41 ENSMUST00000164812.1
ENSMUST00000049567.4
kelch-like ECH-associated protein 1
chr11_+_82045705 0.41 ENSMUST00000021011.2
chemokine (C-C motif) ligand 7
chr5_-_135573036 0.41 ENSMUST00000004936.6
chemokine (C-C motif) ligand 24
chr14_-_77036641 0.40 ENSMUST00000062789.8
laccase (multicopper oxidoreductase) domain containing 1
chr14_-_66124482 0.40 ENSMUST00000070515.1
epoxide hydrolase 2, cytoplasmic
chr1_-_120270253 0.40 ENSMUST00000112639.1
STEAP family member 3
chr1_-_121328024 0.40 ENSMUST00000003818.7
insulin induced gene 2
chr5_-_107726017 0.40 ENSMUST00000159263.2
growth factor independent 1
chr7_-_19950729 0.39 ENSMUST00000043440.6
immunoglobulin superfamily, member 23
chr9_+_109931863 0.39 ENSMUST00000165876.1
microtubule-associated protein 4
chr4_-_45012287 0.39 ENSMUST00000055028.8
ENSMUST00000180217.1
ENSMUST00000107817.2
zinc finger and BTB domain containing 5
chr9_-_122903102 0.38 ENSMUST00000180877.1
ENSMUST00000180486.1
RIKEN cDNA A530083I20 gene
chr9_+_5298517 0.38 ENSMUST00000027015.5
caspase 1
chr1_+_167349976 0.38 ENSMUST00000028004.9
aldehyde dehydrogenase 9, subfamily A1
chr12_+_35047180 0.37 ENSMUST00000048519.9
ENSMUST00000163677.1
sorting nexin 13
chr2_+_135659625 0.37 ENSMUST00000134310.1
phospholipase C, beta 4
chr3_-_122619442 0.37 ENSMUST00000162947.1
formin binding protein 1-like
chr8_-_25016901 0.37 ENSMUST00000084035.5
a disintegrin and metallopeptidase domain 9 (meltrin gamma)
chr9_-_101034892 0.36 ENSMUST00000035116.5
propionyl Coenzyme A carboxylase, beta polypeptide
chr2_-_75981967 0.36 ENSMUST00000099994.3
tetratricopeptide repeat domain 30A1
chr7_+_44012672 0.36 ENSMUST00000048945.4
kallikrein 1-related petidase b26
chr4_+_42035113 0.35 ENSMUST00000098127.1
predicted gene 10597
chr6_-_129507107 0.35 ENSMUST00000183258.1
ENSMUST00000182784.1
ENSMUST00000032265.6
ENSMUST00000162815.1
oxidized low density lipoprotein (lectin-like) receptor 1
chr4_-_40722307 0.35 ENSMUST00000181475.1
predicted gene 6297
chr2_-_60722636 0.35 ENSMUST00000028348.2
ENSMUST00000112517.1
integrin beta 6
chr7_+_3617357 0.35 ENSMUST00000076657.4
ENSMUST00000108644.1
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3
chr1_+_88095054 0.35 ENSMUST00000150634.1
ENSMUST00000058237.7
UDP glucuronosyltransferase 1 family, polypeptide A7C
chr1_-_5070281 0.35 ENSMUST00000147158.1
ENSMUST00000118000.1
regulator of G-protein signaling 20
chr3_+_65109343 0.35 ENSMUST00000159525.1
ENSMUST00000049230.8
potassium voltage-gated channel, shaker-related subfamily, beta member 1
chr17_-_28942255 0.35 ENSMUST00000051526.4
peroxisomal, testis specific 1
chr17_-_36042690 0.34 ENSMUST00000058801.8
ENSMUST00000080015.5
ENSMUST00000077960.6
histocompatibility 2, T region locus 22
chr9_-_101034857 0.34 ENSMUST00000142676.1
ENSMUST00000149322.1
propionyl Coenzyme A carboxylase, beta polypeptide
chr17_+_31520115 0.34 ENSMUST00000046288.8
ENSMUST00000064798.8
NADH dehydrogenase (ubiquinone) flavoprotein 3
chr7_+_43690418 0.34 ENSMUST00000056329.6
kallikrein related-peptidase 14
chr17_-_37280418 0.34 ENSMUST00000077585.2
olfactory receptor 99
chr2_-_27246814 0.34 ENSMUST00000149733.1
sarcosine dehydrogenase
chr11_-_98400393 0.34 ENSMUST00000128897.1
post-GPI attachment to proteins 3
chr19_+_26753588 0.33 ENSMUST00000177116.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr5_+_122707546 0.33 ENSMUST00000081554.6
ENSMUST00000031429.7
ENSMUST00000139631.1
ENSMUST00000142664.1
purinergic receptor P2X, ligand-gated ion channel 4
chr3_-_95251049 0.33 ENSMUST00000098871.4
BCL2/adenovirus E1B 19kD interacting protein like
chr6_+_41392356 0.32 ENSMUST00000049079.7
predicted gene 5771
chr3_-_108200807 0.32 ENSMUST00000106655.1
ENSMUST00000065664.6
cytochrome b-561 domain containing 1
chr18_+_37447641 0.32 ENSMUST00000052387.3
protocadherin beta 14
chr8_-_123983120 0.32 ENSMUST00000075578.6
ATP-binding cassette, sub-family B (MDR/TAP), member 10
chr17_+_21690766 0.32 ENSMUST00000097384.1
predicted gene 10509
chr3_+_28781305 0.31 ENSMUST00000060500.7
eukaryotic translation initiation factor 5A2
chr14_+_80000292 0.31 ENSMUST00000088735.3
olfactomedin 4
chr6_+_138142853 0.31 ENSMUST00000125810.1
microsomal glutathione S-transferase 1
chr3_+_27317028 0.31 ENSMUST00000046383.5
ENSMUST00000174840.1
tumor necrosis factor (ligand) superfamily, member 10
chr2_+_164948219 0.31 ENSMUST00000017881.2
matrix metallopeptidase 9
chr10_+_70204675 0.30 ENSMUST00000020090.1
RIKEN cDNA 2310015B20 gene
chr8_+_25532125 0.30 ENSMUST00000167764.1
fibroblast growth factor receptor 1
chr11_-_98400453 0.30 ENSMUST00000090827.5
post-GPI attachment to proteins 3
chr9_+_99470440 0.30 ENSMUST00000056103.4
RIKEN cDNA 1600029I14 gene
chr4_-_141239453 0.29 ENSMUST00000168138.1
RIKEN cDNA C630004L07 gene
chr10_-_75781411 0.29 ENSMUST00000001715.3
glutathione S-transferase, theta 3
chr11_-_116086929 0.29 ENSMUST00000074628.6
ENSMUST00000106444.3
WW domain binding protein 2
chr13_+_19214103 0.29 ENSMUST00000103558.1
T cell receptor gamma, constant 1
chr8_-_83332416 0.29 ENSMUST00000177594.1
ENSMUST00000053902.3
ELMO/CED-12 domain containing 2
chr3_-_131303144 0.29 ENSMUST00000106337.2
cytochrome P450, family 2, subfamily u, polypeptide 1
chr3_+_146450467 0.28 ENSMUST00000061937.6
ENSMUST00000029840.3
chitobiase, di-N-acetyl-
chr7_-_57386871 0.28 ENSMUST00000068394.6
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 3
chr8_-_25016743 0.28 ENSMUST00000084032.5
a disintegrin and metallopeptidase domain 9 (meltrin gamma)
chr4_-_139968026 0.28 ENSMUST00000105031.2
kelch domain containing 7A
chr1_+_136018062 0.28 ENSMUST00000117950.1
transmembrane protein 9
chr5_-_134456227 0.28 ENSMUST00000111244.1
general transcription factor II I repeat domain-containing 1
chr3_-_95251148 0.28 ENSMUST00000125515.2
ENSMUST00000107195.2
BCL2/adenovirus E1B 19kD interacting protein like
chr6_+_72097561 0.27 ENSMUST00000069994.4
ENSMUST00000114112.1
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
chr11_-_69805617 0.27 ENSMUST00000051025.4
transmembrane protein 102
chr12_+_85746539 0.27 ENSMUST00000040461.3
major facilitator superfamily domain containing 7C
chr3_-_89101907 0.27 ENSMUST00000081848.8
farnesyl diphosphate synthetase
chr16_-_43664145 0.27 ENSMUST00000096065.4
T cell immunoreceptor with Ig and ITIM domains
chr18_+_33464163 0.27 ENSMUST00000097634.3
predicted gene 10549
chr5_+_30013141 0.27 ENSMUST00000026845.7
interleukin 6
chr1_+_136017967 0.27 ENSMUST00000063719.8
ENSMUST00000118832.1
transmembrane protein 9
chr2_+_22622183 0.26 ENSMUST00000028123.3
glutamic acid decarboxylase 2
chr6_+_39573858 0.26 ENSMUST00000140364.1
aarF domain containing kinase 2
chr17_+_34647128 0.26 ENSMUST00000015605.8
ENSMUST00000182587.1
activating transcription factor 6 beta
chr9_+_64179289 0.26 ENSMUST00000034965.6
small nuclear RNA activating complex, polypeptide 5
chr14_-_37135126 0.26 ENSMUST00000042564.9
growth hormone inducible transmembrane protein
chr11_+_48837465 0.26 ENSMUST00000046903.5
tripartite motif-containing 7
chr7_-_140856254 0.26 ENSMUST00000026557.8
blocked early in transport 1 homolog (S. cerevisiae)-like
chr11_-_58502554 0.26 ENSMUST00000170501.2
ENSMUST00000081743.2
olfactory receptor 331
chr19_+_44293676 0.26 ENSMUST00000026221.5
stearoyl-Coenzyme A desaturase 2
chr6_+_83794974 0.25 ENSMUST00000037376.7
N-acetylglucosamine kinase
chr5_-_92083667 0.25 ENSMUST00000113127.3
GTPase activating protein (SH3 domain) binding protein 2
chr13_+_67863324 0.25 ENSMUST00000078471.5
cDNA sequence BC048507
chr17_+_15010266 0.25 ENSMUST00000097395.3
predicted gene 3435
chr11_-_109473598 0.24 ENSMUST00000070152.5
solute carrier family 16 (monocarboxylic acid transporters), member 6
chr13_+_55727345 0.24 ENSMUST00000124968.1
ENSMUST00000021958.5
pterin 4 alpha carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2
chr11_-_4849345 0.24 ENSMUST00000053079.6
ENSMUST00000109910.2
neurofibromatosis 2
chr7_+_142460834 0.24 ENSMUST00000018963.4
ENSMUST00000105967.1
lymphocyte specific 1
chr17_+_15041641 0.24 ENSMUST00000097393.3
ER membrane associated RNA degradation
chr13_-_54611274 0.24 ENSMUST00000049575.7
clathrin, light polypeptide (Lcb)
chr6_+_83795022 0.24 ENSMUST00000113851.1
N-acetylglucosamine kinase
chr1_+_127868773 0.23 ENSMUST00000037649.5
RAB3 GTPase activating protein subunit 1
chr6_+_124997062 0.23 ENSMUST00000159391.1
PILR alpha associated neural protein

Network of associatons between targets according to the STRING database.

First level regulatory network of Mafb

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0072302 negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302) regulation of metanephric ureteric bud development(GO:2001074) positive regulation of metanephric ureteric bud development(GO:2001076)
0.4 1.2 GO:0035480 Notch signaling pathway involved in heart induction(GO:0003137) regulation of Notch signaling pathway involved in heart induction(GO:0035480) positive regulation of Notch signaling pathway involved in heart induction(GO:0035481) regulation of heart induction by regulation of canonical Wnt signaling pathway(GO:0090081)
0.3 0.9 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.3 0.9 GO:0046370 fructose biosynthetic process(GO:0046370)
0.3 1.3 GO:0051012 microtubule sliding(GO:0051012)
0.3 0.8 GO:0046271 phenylpropanoid catabolic process(GO:0046271)
0.2 2.2 GO:0002553 histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
0.2 1.3 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.2 1.3 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.2 0.6 GO:0071332 cellular response to fructose stimulus(GO:0071332)
0.2 1.0 GO:0018992 germ-line sex determination(GO:0018992)
0.2 0.7 GO:0034241 positive regulation of macrophage fusion(GO:0034241)
0.1 0.6 GO:1904124 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.1 0.4 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.1 0.9 GO:0030321 transepithelial chloride transport(GO:0030321)
0.1 0.9 GO:0051410 detoxification of nitrogen compound(GO:0051410) cellular detoxification of nitrogen compound(GO:0070458)
0.1 0.4 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.1 0.6 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.1 0.7 GO:0002003 angiotensin maturation(GO:0002003)
0.1 0.3 GO:1901052 sarcosine metabolic process(GO:1901052) sarcosine catabolic process(GO:1901053)
0.1 0.8 GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.1 0.4 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.1 0.7 GO:0007021 tubulin complex assembly(GO:0007021) lens fiber cell morphogenesis(GO:0070309)
0.1 0.4 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.1 0.5 GO:0002589 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589)
0.1 0.3 GO:0021837 motogenic signaling involved in postnatal olfactory bulb interneuron migration(GO:0021837) positive regulation of mitotic cell cycle DNA replication(GO:1903465)
0.1 0.5 GO:1904058 positive regulation of sensory perception of pain(GO:1904058)
0.1 0.5 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.1 1.2 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 0.5 GO:0009405 pathogenesis(GO:0009405)
0.1 0.9 GO:0015868 purine ribonucleotide transport(GO:0015868)
0.1 1.3 GO:0060363 cranial suture morphogenesis(GO:0060363)
0.1 0.2 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.1 0.4 GO:1902167 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902167)
0.1 0.4 GO:0010956 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) regulation of interleukin-6-mediated signaling pathway(GO:0070103)
0.1 0.2 GO:0097051 establishment of protein localization to endoplasmic reticulum membrane(GO:0097051)
0.1 0.3 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.1 0.4 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.1 0.3 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.1 0.5 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.1 0.3 GO:1903964 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.1 0.5 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.1 0.2 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.1 0.4 GO:0002035 brain renin-angiotensin system(GO:0002035)
0.1 0.3 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.1 0.3 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
0.1 0.2 GO:1900738 psychomotor behavior(GO:0036343) positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.1 0.2 GO:0006657 CDP-choline pathway(GO:0006657)
0.1 0.3 GO:0006538 glutamate catabolic process(GO:0006538)
0.1 0.3 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.1 0.1 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.1 0.9 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.1 0.3 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.1 0.2 GO:0015811 L-cystine transport(GO:0015811)
0.1 0.4 GO:0038044 transforming growth factor-beta secretion(GO:0038044)
0.1 0.2 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.0 0.3 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.0 0.2 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.2 GO:0010248 establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.0 0.3 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.0 0.6 GO:0006026 aminoglycan catabolic process(GO:0006026) glycosaminoglycan catabolic process(GO:0006027)
0.0 0.9 GO:0046697 decidualization(GO:0046697)
0.0 0.2 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.0 0.3 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.0 0.2 GO:0051342 G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199) sensory perception of umami taste(GO:0050917) regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342)
0.0 0.5 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.0 0.3 GO:0007320 insemination(GO:0007320)
0.0 0.8 GO:0001967 suckling behavior(GO:0001967)
0.0 0.8 GO:0039703 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.0 0.2 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0 0.6 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.4 GO:0042136 neurotransmitter biosynthetic process(GO:0042136)
0.0 0.4 GO:0071361 cellular response to ethanol(GO:0071361)
0.0 0.2 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.0 0.1 GO:0001923 B-1 B cell differentiation(GO:0001923)
0.0 0.5 GO:0008272 sulfate transport(GO:0008272)
0.0 0.1 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.0 0.2 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729)
0.0 0.1 GO:0075071 autophagy of host cells involved in interaction with symbiont(GO:0075044) autophagy involved in symbiotic interaction(GO:0075071)
0.0 0.1 GO:0014054 positive regulation of gamma-aminobutyric acid secretion(GO:0014054)
0.0 0.3 GO:0016114 terpenoid biosynthetic process(GO:0016114)
0.0 0.2 GO:1901748 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.0 0.1 GO:0009597 detection of virus(GO:0009597)
0.0 0.3 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.2 GO:0035330 regulation of hippo signaling(GO:0035330)
0.0 0.1 GO:0050847 progesterone receptor signaling pathway(GO:0050847)
0.0 0.2 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 0.1 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.0 0.1 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.0 0.3 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260)
0.0 0.1 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.3 GO:0010820 positive regulation of T cell chemotaxis(GO:0010820)
0.0 0.1 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.0 0.2 GO:0006968 cellular defense response(GO:0006968)
0.0 1.5 GO:0019226 transmission of nerve impulse(GO:0019226)
0.0 1.0 GO:0070542 response to fatty acid(GO:0070542)
0.0 0.1 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.0 0.8 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.2 GO:0046339 phosphatidic acid biosynthetic process(GO:0006654) diacylglycerol metabolic process(GO:0046339)
0.0 0.3 GO:0050907 detection of chemical stimulus involved in sensory perception(GO:0050907)
0.0 1.6 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 0.7 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.6 GO:0015893 drug transport(GO:0015893)
0.0 0.1 GO:0098712 L-glutamate import across plasma membrane(GO:0098712)
0.0 0.1 GO:0042573 retinoic acid metabolic process(GO:0042573)
0.0 0.2 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.2 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.1 GO:2000074 regulation of type B pancreatic cell development(GO:2000074)
0.0 0.2 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.1 GO:0045915 positive regulation of catecholamine metabolic process(GO:0045915) positive regulation of dopamine metabolic process(GO:0045964)
0.0 0.3 GO:0032695 negative regulation of interleukin-12 production(GO:0032695)
0.0 0.0 GO:0046368 GDP-L-fucose metabolic process(GO:0046368)
0.0 0.2 GO:0033005 positive regulation of mast cell activation(GO:0033005)
0.0 0.5 GO:0043277 apoptotic cell clearance(GO:0043277)
0.0 0.3 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0 0.3 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.8 GO:0019915 lipid storage(GO:0019915)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.2 1.3 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 0.4 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.1 1.5 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 0.8 GO:0042825 TAP complex(GO:0042825)
0.1 0.4 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.1 0.7 GO:0031983 vesicle lumen(GO:0031983)
0.1 0.3 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 0.5 GO:1990357 terminal web(GO:1990357)
0.1 0.6 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.1 0.6 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.2 GO:0045160 myosin I complex(GO:0045160)
0.0 1.1 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.9 GO:0005922 connexon complex(GO:0005922)
0.0 0.3 GO:0042581 specific granule(GO:0042581)
0.0 0.5 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.6 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.1 GO:0031021 interphase microtubule organizing center(GO:0031021)
0.0 0.3 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.8 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.8 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.3 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.7 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 0.1 GO:0043293 apoptosome(GO:0043293)
0.0 0.1 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 0.4 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.3 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.2 GO:0042587 glycogen granule(GO:0042587)
0.0 1.3 GO:0005746 mitochondrial respiratory chain(GO:0005746)
0.0 0.9 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.1 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.0 0.1 GO:0097361 CIA complex(GO:0097361)
0.0 0.1 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.0 0.5 GO:0008305 integrin complex(GO:0008305)
0.0 1.5 GO:0005930 axoneme(GO:0005930)
0.0 0.4 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.3 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.1 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.1 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 0.1 GO:0044754 autolysosome(GO:0044754)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0071568 UFM1 transferase activity(GO:0071568)
0.3 0.9 GO:0015065 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.3 0.9 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.3 2.0 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.2 0.7 GO:0004658 propionyl-CoA carboxylase activity(GO:0004658)
0.2 0.9 GO:0019970 interleukin-11 receptor activity(GO:0004921) interleukin-11 binding(GO:0019970)
0.2 1.3 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.2 2.1 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.2 0.9 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.2 0.5 GO:0045127 N-acetylglucosamine kinase activity(GO:0045127)
0.1 0.4 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.1 0.1 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.1 0.3 GO:0046997 sarcosine dehydrogenase activity(GO:0008480) oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.1 0.8 GO:0046979 TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
0.1 0.4 GO:0008147 structural constituent of bone(GO:0008147)
0.1 0.5 GO:0097603 temperature-gated ion channel activity(GO:0097603)
0.1 0.6 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 0.5 GO:0004875 complement receptor activity(GO:0004875) scavenger receptor binding(GO:0005124)
0.1 0.4 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.1 0.3 GO:0004568 chitinase activity(GO:0004568)
0.1 0.2 GO:0004816 asparagine-tRNA ligase activity(GO:0004816)
0.1 0.5 GO:0043559 insulin binding(GO:0043559)
0.1 0.2 GO:0030350 iron-responsive element binding(GO:0030350)
0.1 0.3 GO:0032896 palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.1 0.4 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.1 0.2 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211)
0.1 0.2 GO:0005333 norepinephrine transmembrane transporter activity(GO:0005333)
0.1 0.9 GO:0005243 gap junction channel activity(GO:0005243)
0.1 0.8 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.1 0.3 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.1 0.8 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 0.2 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.1 0.5 GO:0039706 co-receptor binding(GO:0039706)
0.1 0.6 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.1 0.4 GO:0000293 ferric-chelate reductase activity(GO:0000293) cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.2 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
0.0 0.3 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 2.6 GO:0005158 insulin receptor binding(GO:0005158)
0.0 1.0 GO:0045125 bioactive lipid receptor activity(GO:0045125)
0.0 0.3 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.0 1.2 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 1.2 GO:0043295 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0 0.6 GO:0070513 death domain binding(GO:0070513)
0.0 0.3 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 0.5 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.0 0.1 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0 1.2 GO:0043236 laminin binding(GO:0043236)
0.0 0.7 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.4 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.3 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.5 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.2 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.5 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.6 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.4 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.1 GO:0004771 sterol esterase activity(GO:0004771)
0.0 0.5 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.6 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.6 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.6 GO:0031402 sodium ion binding(GO:0031402)
0.0 0.6 GO:0015238 drug transmembrane transporter activity(GO:0015238)
0.0 0.2 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.2 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 0.3 GO:0070402 NADPH binding(GO:0070402)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.5 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.3 GO:0070330 aromatase activity(GO:0070330)
0.0 0.2 GO:0003951 NAD+ kinase activity(GO:0003951) diacylglycerol kinase activity(GO:0004143)
0.0 0.2 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.0 0.4 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 0.2 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.4 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.1 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.0 0.3 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.3 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.5 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.1 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.3 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.2 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.3 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.2 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.1 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.3 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.7 GO:0008146 sulfotransferase activity(GO:0008146)
0.0 0.2 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.4 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.6 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.8 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 0.8 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.3 ST STAT3 PATHWAY STAT3 Pathway
0.0 0.7 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 0.4 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 1.9 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.1 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.8 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.2 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.4 PID IFNG PATHWAY IFN-gamma pathway
0.0 0.4 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.3 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.6 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.3 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.1 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.1 2.0 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.1 0.7 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.1 0.6 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 1.2 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.1 1.2 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.1 0.6 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.9 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 1.8 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.9 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.7 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.8 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.4 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 1.2 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.7 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.3 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 1.2 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.3 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.4 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.6 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.3 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.0 0.3 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 0.5 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.7 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.3 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.5 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.4 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 0.3 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.1 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.3 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.4 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation