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12D miR HR13_24

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Results for Irf4

Z-value: 0.82

Motif logo

Transcription factors associated with Irf4

Gene Symbol Gene ID Gene Info
ENSMUSG00000021356.3 interferon regulatory factor 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Irf4mm10_v2_chr13_+_30749226_30749247-0.586.3e-02Click!

Activity profile of Irf4 motif

Sorted Z-values of Irf4 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_16688405 1.79 ENSMUST00000026881.4
lymphocyte antigen 96
chr11_+_69966896 1.66 ENSMUST00000151515.1
claudin 7
chr19_-_58454580 1.13 ENSMUST00000129100.1
ENSMUST00000123957.1
glial cell line derived neurotrophic factor family receptor alpha 1
chr3_+_138065052 1.00 ENSMUST00000163080.2
RIKEN cDNA 1110002E22 gene
chr6_+_96115249 0.87 ENSMUST00000075080.5
family with sequence similarity 19, member A1
chr17_-_28915314 0.81 ENSMUST00000062357.4
RIKEN cDNA 4930539E08 gene
chr19_-_58455398 0.78 ENSMUST00000026076.7
glial cell line derived neurotrophic factor family receptor alpha 1
chr4_-_89311021 0.75 ENSMUST00000097981.4
cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
chr1_+_99772765 0.74 ENSMUST00000086738.3
contactin associated protein-like 5B
chr4_-_19922599 0.73 ENSMUST00000029900.5
ATPase, H+ transporting, lysosomal V0 subunit D2
chr2_-_152831112 0.72 ENSMUST00000128172.1
BCL2-like 1
chr16_-_24393588 0.69 ENSMUST00000181640.1
RIKEN cDNA 1110054M08 gene
chr19_-_58455161 0.67 ENSMUST00000135730.1
ENSMUST00000152507.1
glial cell line derived neurotrophic factor family receptor alpha 1
chr15_-_66560997 0.67 ENSMUST00000048372.5
transmembrane protein 71
chr5_+_102481374 0.67 ENSMUST00000094559.2
ENSMUST00000073302.5
Rho GTPase activating protein 24
chrX_-_134161928 0.66 ENSMUST00000033611.4
X Kell blood group precursor related X linked
chr10_-_64090265 0.66 ENSMUST00000105439.1
leucine rich repeat transmembrane neuronal 3
chr10_+_69212676 0.65 ENSMUST00000167384.1
Rho-related BTB domain containing 1
chr19_+_34640871 0.64 ENSMUST00000102824.3
interferon-induced protein with tetratricopeptide repeats 1
chr5_+_102481546 0.64 ENSMUST00000112854.1
Rho GTPase activating protein 24
chr8_-_35826435 0.62 ENSMUST00000060128.5
claudin 23
chr19_+_5568002 0.61 ENSMUST00000096318.3
adaptor-related protein complex 5, beta 1 subunit
chr5_+_147269959 0.61 ENSMUST00000085591.5
pancreatic and duodenal homeobox 1
chr3_+_3634145 0.60 ENSMUST00000108394.1
hepatocyte nuclear factor 4, gamma
chr12_-_79007276 0.60 ENSMUST00000056660.6
ENSMUST00000174721.1
transmembrane protein 229B
chr7_+_4460687 0.60 ENSMUST00000167298.1
ENSMUST00000171445.1
EPS8-like 1
chr16_-_52454074 0.59 ENSMUST00000023312.7
activated leukocyte cell adhesion molecule
chr10_+_69212634 0.58 ENSMUST00000020101.5
Rho-related BTB domain containing 1
chr17_-_6782775 0.56 ENSMUST00000064234.6
ezrin
chr2_+_128126030 0.56 ENSMUST00000089634.5
ENSMUST00000019281.7
ENSMUST00000110341.2
ENSMUST00000103211.1
ENSMUST00000103210.1
BCL2-like 11 (apoptosis facilitator)
chrX_-_101222426 0.54 ENSMUST00000120389.1
ENSMUST00000156473.1
ENSMUST00000077876.3
sorting nexin 12
chr3_+_3508024 0.54 ENSMUST00000108393.1
ENSMUST00000017832.8
hepatocyte nuclear factor 4, gamma
chr6_+_71282280 0.53 ENSMUST00000080949.7
lysine-rich coiled-coil 1
chr1_+_188263034 0.53 ENSMUST00000060479.7
Usher syndrome 2A (autosomal recessive, mild)
chr18_+_37264998 0.52 ENSMUST00000052366.3
protocadherin beta 1
chr13_+_23555023 0.52 ENSMUST00000045301.6
histone cluster 1, H1d
chr18_+_82855894 0.50 ENSMUST00000181345.1
ENSMUST00000180631.1
RIKEN cDNA 4930445N18 gene
chr8_+_61928081 0.49 ENSMUST00000154398.1
ENSMUST00000093485.2
ENSMUST00000156980.1
ENSMUST00000070631.7
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
chr1_-_174921813 0.48 ENSMUST00000055294.3
gremlin 2 homolog, cysteine knot superfamily (Xenopus laevis)
chr9_+_45042425 0.48 ENSMUST00000034600.4
myelin protein zero-like 2
chr19_-_57197556 0.46 ENSMUST00000099294.2
actin-binding LIM protein 1
chr15_+_52295509 0.44 ENSMUST00000037240.2
solute carrier family 30 (zinc transporter), member 8
chr3_+_89421619 0.43 ENSMUST00000094378.3
ENSMUST00000137793.1
src homology 2 domain-containing transforming protein C1
chr2_-_152830615 0.42 ENSMUST00000146380.1
ENSMUST00000134902.1
ENSMUST00000134357.1
ENSMUST00000109820.3
BCL2-like 1
chr6_-_39118211 0.41 ENSMUST00000038398.6
poly (ADP-ribose) polymerase family, member 12
chrX_+_136707976 0.41 ENSMUST00000055104.5
transcription elongation factor A (SII)-like 1
chr1_-_93101854 0.40 ENSMUST00000171796.1
ENSMUST00000171556.1
kinesin family member 1A
chr2_-_131174653 0.39 ENSMUST00000127987.1
sperm flagellar 1
chr7_+_78914216 0.39 ENSMUST00000120331.2
interferon-stimulated protein
chr16_-_26371828 0.38 ENSMUST00000023154.2
claudin 1
chrX_-_9469288 0.38 ENSMUST00000015484.3
cytochrome b-245, beta polypeptide
chr4_-_133263042 0.38 ENSMUST00000105908.3
ENSMUST00000030674.7
synaptotagmin-like 1
chr10_+_86022189 0.37 ENSMUST00000120344.1
ENSMUST00000117597.1
F-box protein 7
chrX_+_139563316 0.37 ENSMUST00000113027.1
ring finger protein 128
chr3_-_108200807 0.35 ENSMUST00000106655.1
ENSMUST00000065664.6
cytochrome b-561 domain containing 1
chr1_+_61638819 0.33 ENSMUST00000138768.1
ENSMUST00000075374.3
par-3 partitioning defective 3 homolog B (C. elegans)
chr10_-_86022325 0.33 ENSMUST00000181665.1
RIKEN cDNA A230060F14 gene
chr13_-_19395728 0.33 ENSMUST00000039694.7
STARD3 N-terminal like
chr3_+_95526777 0.32 ENSMUST00000015667.2
ENSMUST00000116304.2
cathepsin S
chr10_-_24109582 0.32 ENSMUST00000041180.5
trace amine-associated receptor 9
chr16_+_24393350 0.31 ENSMUST00000038053.6
LIM domain containing preferred translocation partner in lipoma
chr7_-_126396715 0.31 ENSMUST00000075671.4
nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2 interacting protein
chr10_-_52195244 0.31 ENSMUST00000020045.3
Ros1 proto-oncogene
chr7_-_141266415 0.30 ENSMUST00000106023.1
ENSMUST00000097952.2
ENSMUST00000026571.4
interferon regulatory factor 7
chr10_+_39612934 0.30 ENSMUST00000019987.6
TRAF3 interacting protein 2
chr1_-_93101825 0.30 ENSMUST00000112958.2
kinesin family member 1A
chr14_-_79223876 0.29 ENSMUST00000040802.4
zinc finger protein 957
chr2_-_127788854 0.29 ENSMUST00000028857.7
ENSMUST00000110357.1
nephronophthisis 1 (juvenile) homolog (human)
chr7_-_65370908 0.28 ENSMUST00000032729.6
tight junction protein 1
chr4_-_129239165 0.27 ENSMUST00000097873.3
expressed sequence C77080
chr6_-_97060407 0.27 ENSMUST00000089295.4
family with sequence similarity 19, member A4
chr4_-_46536134 0.26 ENSMUST00000046897.6
tripartite motif-containing 14
chr2_+_23069057 0.26 ENSMUST00000114526.1
ENSMUST00000114529.2
acyl-Coenzyme A binding domain containing 5
chr1_-_161876656 0.26 ENSMUST00000048377.5
SUN domain containing ossification factor
chr15_+_102977032 0.25 ENSMUST00000001706.6
homeobox C9
chr12_-_26456423 0.25 ENSMUST00000020970.7
radical S-adenosyl methionine domain containing 2
chr2_-_51934644 0.24 ENSMUST00000165313.1
RNA binding motif protein 43
chr10_+_128706251 0.24 ENSMUST00000054125.8
premelanosome protein
chr2_+_23069210 0.24 ENSMUST00000155602.1
acyl-Coenzyme A binding domain containing 5
chr4_-_4138817 0.23 ENSMUST00000133567.1
preproenkephalin
chr9_+_98864767 0.23 ENSMUST00000167951.1
RIKEN cDNA 2410012M07 gene
chr18_+_37484955 0.22 ENSMUST00000053856.4
protocadherin beta 17
chr9_-_117251801 0.22 ENSMUST00000172564.1
RNA binding motif, single stranded interacting protein
chr13_-_23710714 0.21 ENSMUST00000091707.6
ENSMUST00000006787.7
ENSMUST00000091706.6
hemochromatosis
chr19_-_57197377 0.20 ENSMUST00000111546.1
actin-binding LIM protein 1
chr3_+_68691424 0.19 ENSMUST00000107816.2
interleukin 12a
chr16_+_43235856 0.18 ENSMUST00000146708.1
zinc finger and BTB domain containing 20
chr19_-_57197496 0.18 ENSMUST00000111544.1
actin-binding LIM protein 1
chr19_+_46623387 0.17 ENSMUST00000111855.4
WW domain binding protein 1 like
chr1_+_187215737 0.17 ENSMUST00000160471.1
G patch domain containing 2
chr9_-_77251871 0.17 ENSMUST00000183955.1
muscular LMNA-interacting protein
chr2_-_131175201 0.17 ENSMUST00000110218.2
sperm flagellar 1
chr14_-_66124482 0.17 ENSMUST00000070515.1
epoxide hydrolase 2, cytoplasmic
chr19_-_57197435 0.17 ENSMUST00000111550.1
actin-binding LIM protein 1
chr13_+_19214103 0.16 ENSMUST00000103558.1
T cell receptor gamma, constant 1
chr19_+_8850785 0.16 ENSMUST00000096257.2
LRRN4 C-terminal like
chr16_+_35938972 0.16 ENSMUST00000023622.6
ENSMUST00000114877.1
poly (ADP-ribose) polymerase family, member 9
chr10_-_64090241 0.15 ENSMUST00000133588.1
leucine rich repeat transmembrane neuronal 3
chr17_+_34203527 0.15 ENSMUST00000025197.5
transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
chr3_+_152346465 0.15 ENSMUST00000026507.6
ENSMUST00000117492.2
ubiquitin specific peptidase 33
chr9_-_77251829 0.15 ENSMUST00000184322.1
ENSMUST00000184316.1
muscular LMNA-interacting protein
chr9_-_111057235 0.14 ENSMUST00000111888.1
chemokine (C-C motif) receptor-like 2
chr6_+_82041623 0.14 ENSMUST00000042974.8
eva-1 homolog A (C. elegans)
chr14_-_122465677 0.13 ENSMUST00000039118.6
zinc finger protein of the cerebellum 5
chr12_+_52699297 0.13 ENSMUST00000095737.3
A kinase (PRKA) anchor protein 6
chr10_+_21882184 0.13 ENSMUST00000120509.1
serum/glucocorticoid regulated kinase 1
chr10_+_28668360 0.13 ENSMUST00000060409.6
ENSMUST00000056097.4
ENSMUST00000105516.2
thymocyte selection associated
chr2_-_9878580 0.13 ENSMUST00000102976.3
GATA binding protein 3
chr11_+_67321638 0.13 ENSMUST00000108684.1
myosin, heavy polypeptide 13, skeletal muscle
chr19_+_34607927 0.12 ENSMUST00000076249.5
RIKEN cDNA I830012O16 gene
chr11_-_107470699 0.12 ENSMUST00000103064.3
phosphatidylinositol transfer protein, cytoplasmic 1
chr1_+_175631996 0.12 ENSMUST00000040250.8
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr12_+_111417430 0.12 ENSMUST00000072646.6
exocyst complex component 3-like 4
chr14_+_60732906 0.12 ENSMUST00000162945.1
spermatogenesis associated 13
chr13_+_24614608 0.11 ENSMUST00000091694.3
family with sequence similarity 65, member B
chr16_+_25801907 0.11 ENSMUST00000040231.6
ENSMUST00000115306.1
ENSMUST00000115304.1
ENSMUST00000115305.1
transformation related protein 63
chr9_+_99470440 0.11 ENSMUST00000056103.4
RIKEN cDNA 1600029I14 gene
chr16_-_55838827 0.11 ENSMUST00000096026.2
ENSMUST00000036273.6
ENSMUST00000114457.1
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, zeta
chrX_+_112615301 0.10 ENSMUST00000122805.1
zinc finger protein 711
chr4_-_46536096 0.10 ENSMUST00000102924.2
tripartite motif-containing 14
chr13_+_20090500 0.10 ENSMUST00000165249.2
engulfment and cell motility 1
chr6_-_129100903 0.09 ENSMUST00000032258.6
C-type lectin domain family 2, member e
chr1_+_57845534 0.09 ENSMUST00000169772.1
spermatogenesis associated, serine-rich 2-like
chr11_+_78245743 0.09 ENSMUST00000002133.8
stromal cell derived factor 2
chr11_+_67321778 0.09 ENSMUST00000180845.1
myosin, heavy polypeptide 13, skeletal muscle
chr13_-_100616911 0.08 ENSMUST00000168772.1
ENSMUST00000163163.1
ENSMUST00000022137.7
MARVEL (membrane-associating) domain containing 2
chr2_+_71453276 0.08 ENSMUST00000037210.8
methionyl aminopeptidase type 1D (mitochondrial)
chr17_-_34862473 0.08 ENSMUST00000025229.4
ENSMUST00000176203.2
ENSMUST00000128767.1
complement factor B
chr1_+_175632169 0.08 ENSMUST00000097458.3
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr10_+_18235030 0.08 ENSMUST00000181897.1
predicted gene 10827
chr17_-_34862122 0.08 ENSMUST00000154526.1
complement factor B
chrX_+_20848543 0.08 ENSMUST00000001155.4
ENSMUST00000122312.1
ENSMUST00000120356.1
ENSMUST00000122850.1
v-raf murine sarcoma 3611 viral oncogene homolog
chr17_+_8849974 0.08 ENSMUST00000115720.1
phosphodiesterase 10A
chr13_+_20090538 0.07 ENSMUST00000072519.5
engulfment and cell motility 1
chr19_+_41029275 0.07 ENSMUST00000051806.4
ENSMUST00000112200.1
deoxynucleotidyltransferase, terminal
chr11_+_78343475 0.07 ENSMUST00000002127.7
ENSMUST00000108295.1
unc-119 homolog (C. elegans)
chr1_-_153851189 0.07 ENSMUST00000059607.6
RIKEN cDNA 5830403L16 gene
chr10_-_41490335 0.07 ENSMUST00000019965.6
sphingomyelin phosphodiesterase 2, neutral
chr19_-_24225015 0.07 ENSMUST00000099558.4
tight junction protein 2
chr8_+_90828820 0.07 ENSMUST00000109614.2
ENSMUST00000048665.6
chromodomain helicase DNA binding protein 9
chrX_-_106840572 0.07 ENSMUST00000062010.9
zinc finger, CCHC domain containing 5
chr1_+_58393119 0.06 ENSMUST00000050552.8
basic leucine zipper and W2 domains 1
chr11_-_43836243 0.06 ENSMUST00000167574.1
adrenergic receptor, alpha 1b
chr9_+_58629102 0.05 ENSMUST00000176250.1
neuroplastin
chr19_+_56397100 0.05 ENSMUST00000026062.9
caspase 7
chr7_-_16286744 0.05 ENSMUST00000150528.2
ENSMUST00000118976.2
ENSMUST00000146609.2
coiled-coil domain containing 9
chr1_-_14310198 0.05 ENSMUST00000168081.2
ENSMUST00000027066.6
eyes absent 1 homolog (Drosophila)
chr5_+_36796228 0.05 ENSMUST00000181278.1
predicted gene, 26605
chr11_+_46810792 0.05 ENSMUST00000068877.6
T cell immunoglobulin and mucin domain containing 4
chr17_-_30612613 0.05 ENSMUST00000167624.1
ENSMUST00000024823.6
glyoxalase 1
chr18_+_7869707 0.04 ENSMUST00000166062.1
ENSMUST00000169010.1
WW domain containing adaptor with coiled-coil
chr19_+_55180716 0.03 ENSMUST00000154886.1
ENSMUST00000120936.1
tectorin beta
chr12_-_4477138 0.03 ENSMUST00000085814.3
nuclear receptor coactivator 1
chr15_-_50889691 0.03 ENSMUST00000165201.2
ENSMUST00000184458.1
trichorhinophalangeal syndrome I (human)
chr1_-_97977233 0.03 ENSMUST00000161567.1
peptidylglycine alpha-amidating monooxygenase
chr5_-_104021799 0.03 ENSMUST00000119025.1
hydroxysteroid (17-beta) dehydrogenase 11
chr16_-_43664145 0.03 ENSMUST00000096065.4
T cell immunoreceptor with Ig and ITIM domains
chr14_+_65266701 0.02 ENSMUST00000169656.1
F-box protein 16
chr11_+_65162132 0.02 ENSMUST00000181156.1
RIKEN cDNA B430202K04 gene
chr17_+_35424870 0.02 ENSMUST00000113879.3
histocompatibility 2, Q region locus 6
chrX_+_159303266 0.02 ENSMUST00000112491.1
ribosomal protein S6 kinase polypeptide 3
chr1_-_84935089 0.02 ENSMUST00000027422.5
solute carrier family 16 (monocarboxylic acid transporters), member 14
chr9_+_65346066 0.02 ENSMUST00000048184.2
programmed cell death 7
chr11_+_53720790 0.01 ENSMUST00000048605.2
interleukin 5
chr13_-_107890059 0.01 ENSMUST00000105097.2
zinc finger SWIM-type containing 6
chr10_-_78351690 0.01 ENSMUST00000166360.1
1-acylglycerol-3-phosphate O-acyltransferase 3
chr13_+_42052015 0.01 ENSMUST00000060148.5
human immunodeficiency virus type I enhancer binding protein 1
chr16_+_92058270 0.01 ENSMUST00000047429.8
ENSMUST00000113975.2
mitochondrial ribosomal protein S6
solute carrier family 5 (inositol transporters), member 3
chr10_+_94575257 0.01 ENSMUST00000121471.1
transmembrane and coiled coil domains 3

Network of associatons between targets according to the STRING database.

First level regulatory network of Irf4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.8 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.3 1.1 GO:0046898 response to cycloheximide(GO:0046898)
0.2 0.7 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.2 0.6 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.2 0.5 GO:2000642 negative regulation of early endosome to late endosome transport(GO:2000642)
0.2 0.5 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.2 0.5 GO:0060300 regulation of cytokine activity(GO:0060300)
0.1 1.3 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.1 0.6 GO:1902263 cellular process regulating host cell cycle in response to virus(GO:0060154) apoptotic process involved in embryonic digit morphogenesis(GO:1902263)
0.1 0.6 GO:0009730 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.1 0.3 GO:0034769 basement membrane disassembly(GO:0034769)
0.1 0.5 GO:0048496 maintenance of organ identity(GO:0048496)
0.1 0.8 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.1 1.7 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.1 0.4 GO:1990839 response to endothelin(GO:1990839)
0.1 0.2 GO:0034165 positive regulation of toll-like receptor 9 signaling pathway(GO:0034165)
0.1 0.5 GO:0016584 nucleosome positioning(GO:0016584)
0.1 0.4 GO:0002589 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589)
0.1 0.5 GO:0030242 pexophagy(GO:0030242)
0.1 0.1 GO:2000611 positive regulation of thyroid hormone generation(GO:2000611)
0.1 0.3 GO:0034124 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124)
0.1 0.2 GO:0046271 phenylpropanoid catabolic process(GO:0046271) olefin metabolic process(GO:1900673)
0.1 0.3 GO:0010966 regulation of phosphate transport(GO:0010966)
0.1 0.8 GO:0060253 negative regulation of glial cell proliferation(GO:0060253)
0.1 0.6 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.0 0.4 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.0 0.4 GO:1903599 positive regulation of mitophagy(GO:1903599)
0.0 0.2 GO:2000987 positive regulation of fear response(GO:1903367) positive regulation of behavioral fear response(GO:2000987)
0.0 0.6 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.0 0.2 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.4 GO:0061088 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.0 0.7 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.1 GO:0060197 cloacal septation(GO:0060197)
0.0 0.3 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.2 GO:2000510 positive regulation of dendritic cell chemotaxis(GO:2000510)
0.0 0.1 GO:0001982 baroreceptor response to decreased systemic arterial blood pressure(GO:0001982)
0.0 0.1 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316) positive regulation of delayed rectifier potassium channel activity(GO:1902261) positive regulation of cAMP-dependent protein kinase activity(GO:2000481)
0.0 0.7 GO:0007035 vacuolar acidification(GO:0007035)
0.0 0.2 GO:1900378 positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.0 0.1 GO:2001287 negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.0 0.1 GO:0072734 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.0 0.1 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.0 0.3 GO:0001783 B cell apoptotic process(GO:0001783)
0.0 0.6 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 2.5 GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation(GO:0050731)
0.0 0.2 GO:0006957 complement activation, alternative pathway(GO:0006957) response to thyroid hormone(GO:0097066)
0.0 0.2 GO:0060330 regulation of response to interferon-gamma(GO:0060330)
0.0 0.1 GO:1902683 regulation of receptor localization to synapse(GO:1902683)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.8 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.2 0.6 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.2 1.7 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 0.5 GO:1990696 USH2 complex(GO:1990696)
0.1 0.2 GO:0032280 symmetric synapse(GO:0032280)
0.1 0.4 GO:1990037 Lewy body core(GO:1990037)
0.1 0.7 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.2 GO:0032585 multivesicular body membrane(GO:0032585)
0.0 1.0 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.4 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.2 GO:1990357 terminal web(GO:1990357)
0.0 0.3 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 0.6 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.2 GO:0042825 TAP complex(GO:0042825)
0.0 2.6 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.1 GO:0033010 paranodal junction(GO:0033010)
0.0 0.5 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.2 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.6 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 0.7 GO:0005871 kinesin complex(GO:0005871)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.8 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.1 1.1 GO:0051434 BH3 domain binding(GO:0051434)
0.1 0.4 GO:0048408 epidermal growth factor binding(GO:0048408)
0.1 0.2 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.1 0.4 GO:0008859 exoribonuclease II activity(GO:0008859)
0.1 0.2 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.1 0.4 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.8 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.5 GO:0036122 BMP binding(GO:0036122)
0.0 0.7 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.2 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.6 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.3 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.2 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.0 0.2 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.1 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.2 GO:0046980 peptide antigen-transporting ATPase activity(GO:0015433) tapasin binding(GO:0046980)
0.0 0.6 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.3 GO:0071253 connexin binding(GO:0071253)
0.0 0.3 GO:0031386 protein tag(GO:0031386)
0.0 0.4 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.1 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 0.4 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.6 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.1 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.1 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 1.9 GO:0005178 integrin binding(GO:0005178)
0.0 0.4 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.3 GO:0043236 laminin binding(GO:0043236)
0.0 1.1 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 0.3 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.5 GO:0050699 WW domain binding(GO:0050699)
0.0 0.1 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 0.1 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1 1.8 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 3.0 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.5 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.4 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.5 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.1 0.3 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 1.1 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 1.8 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 2.0 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 2.6 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 1.0 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.5 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 1.1 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.6 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.3 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 0.8 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.4 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.4 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.5 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.6 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.8 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.3 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.2 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade