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12D miR HR13_24

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Results for Sox5_Sry

Z-value: 1.72

Motif logo

Transcription factors associated with Sox5_Sry

Gene Symbol Gene ID Gene Info
ENSMUSG00000041540.10 SRY (sex determining region Y)-box 5
ENSMUSG00000069036.3 sex determining region of Chr Y

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Sox5mm10_v2_chr6_-_143947092_1439471110.766.7e-03Click!

Activity profile of Sox5_Sry motif

Sorted Z-values of Sox5_Sry motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_129121889 6.71 ENSMUST00000139450.1
ENSMUST00000125931.1
ENSMUST00000116444.2
hippocalcin
chr10_+_88091070 4.42 ENSMUST00000048621.7
pro-melanin-concentrating hormone
chr4_+_122995944 3.89 ENSMUST00000106252.2
v-myc myelocytomatosis viral oncogene homolog, lung carcinoma derived (avian)
chr4_+_122996035 3.73 ENSMUST00000030407.7
v-myc myelocytomatosis viral oncogene homolog, lung carcinoma derived (avian)
chr10_-_45470201 3.61 ENSMUST00000079390.6
lin-28 homolog B (C. elegans)
chrX_-_104201126 3.49 ENSMUST00000056502.6
ENSMUST00000118314.1
expressed sequence C77370
chr5_+_30711564 3.18 ENSMUST00000114729.1
dihydropyrimidinase-like 5
chr5_+_30711849 3.18 ENSMUST00000088081.4
ENSMUST00000101442.3
dihydropyrimidinase-like 5
chr9_+_47530173 2.96 ENSMUST00000114548.1
ENSMUST00000152459.1
ENSMUST00000143026.1
ENSMUST00000085909.2
ENSMUST00000114547.1
ENSMUST00000034581.3
cell adhesion molecule 1
chr9_+_26733728 2.87 ENSMUST00000160899.1
ENSMUST00000161431.1
ENSMUST00000159799.1
beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)
chr12_+_40446050 2.57 ENSMUST00000037488.6
dedicator of cytokinesis 4
chr9_-_35116804 2.52 ENSMUST00000034537.6
ST3 beta-galactoside alpha-2,3-sialyltransferase 4
chr9_+_26733845 2.41 ENSMUST00000115269.2
beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)
chr11_+_94044111 2.29 ENSMUST00000132079.1
sperm associated antigen 9
chr1_+_53061637 1.99 ENSMUST00000027269.5
myostatin
chr18_-_43687695 1.95 ENSMUST00000082254.6
janus kinase and microtubule interacting protein 2
chr11_+_44617310 1.90 ENSMUST00000081265.5
ENSMUST00000101326.3
ENSMUST00000109268.1
early B cell factor 1
chr3_+_68584154 1.88 ENSMUST00000182997.1
schwannomin interacting protein 1
chr11_+_94044241 1.87 ENSMUST00000103168.3
sperm associated antigen 9
chr11_+_94044194 1.86 ENSMUST00000092777.4
ENSMUST00000075695.6
sperm associated antigen 9
chr6_-_87335758 1.80 ENSMUST00000042025.9
anthrax toxin receptor 1
chr17_-_70849644 1.77 ENSMUST00000134654.1
ENSMUST00000172229.1
ENSMUST00000127719.1
TGFB-induced factor homeobox 1
chr19_+_53310495 1.76 ENSMUST00000003870.7
Max interacting protein 1
chr16_-_57754707 1.69 ENSMUST00000089332.4
collagen, type VIII, alpha 1
chr8_-_84773381 1.69 ENSMUST00000109764.1
nuclear factor I/X
chr18_-_43059418 1.59 ENSMUST00000025377.7
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform
chrX_-_104201099 1.54 ENSMUST00000087879.4
expressed sequence C77370
chr2_+_25180737 1.50 ENSMUST00000104999.2
Notch-regulated ankyrin repeat protein
chr1_+_34005872 1.48 ENSMUST00000182296.1
dystonin
chr18_+_69593361 1.44 ENSMUST00000114978.2
ENSMUST00000114977.1
transcription factor 4
chr1_+_55406163 1.42 ENSMUST00000042986.8
phospholipase C-like 1
chr11_+_94044331 1.38 ENSMUST00000024979.8
sperm associated antigen 9
chr7_+_82174796 1.36 ENSMUST00000032874.7
SH3-domain GRB2-like 3
chr7_+_16309577 1.34 ENSMUST00000002152.6
BCL2 binding component 3
chrX_+_93654863 1.31 ENSMUST00000113933.2
phosphate cytidylyltransferase 1, choline, beta isoform
chr10_+_69706326 1.28 ENSMUST00000182992.1
ankyrin 3, epithelial
chr1_+_158362261 1.27 ENSMUST00000046110.9
astrotactin 1
chr1_+_6730135 1.25 ENSMUST00000155921.1
suppression of tumorigenicity 18
chr6_+_15185456 1.23 ENSMUST00000115472.1
ENSMUST00000115474.1
ENSMUST00000031545.7
ENSMUST00000137628.1
forkhead box P2
chr4_+_17853451 1.22 ENSMUST00000029881.3
matrix metallopeptidase 16
chr6_+_122513583 1.20 ENSMUST00000032210.7
ENSMUST00000148517.1
microfibrillar associated protein 5
chr3_-_27896360 1.20 ENSMUST00000058077.3
transmembrane protein 212
chr16_+_57549232 1.16 ENSMUST00000159414.1
filamin A interacting protein 1-like
chr5_-_138171248 1.14 ENSMUST00000153867.1
minichromosome maintenance deficient 7 (S. cerevisiae)
chr18_+_11633276 1.13 ENSMUST00000115861.2
retinoblastoma binding protein 8
chr12_+_29528382 1.11 ENSMUST00000049784.9
myelin transcription factor 1-like
chr5_-_90640464 1.11 ENSMUST00000031317.6
Ras association (RalGDS/AF-6) domain family member 6
chr2_+_102658640 1.10 ENSMUST00000080210.3
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr5_-_138170992 1.09 ENSMUST00000139983.1
minichromosome maintenance deficient 7 (S. cerevisiae)
chr10_+_18407658 1.09 ENSMUST00000037341.7
NHS-like 1
chr6_+_34709610 1.08 ENSMUST00000031775.6
caldesmon 1
chr16_-_78576649 1.06 ENSMUST00000114220.1
ENSMUST00000114219.1
ENSMUST00000114218.1
DNA segment, Chr 16, ERATO Doi 472, expressed
chr17_-_35838208 1.05 ENSMUST00000134978.2
tubulin, beta 5 class I
chr7_+_16310412 1.04 ENSMUST00000136781.1
BCL2 binding component 3
chr16_-_4559720 1.03 ENSMUST00000005862.7
transcription factor AP4
chr6_+_34709442 1.02 ENSMUST00000115021.1
caldesmon 1
chr3_-_92083132 1.00 ENSMUST00000058150.6
loricrin
chr7_-_101921186 1.00 ENSMUST00000106965.1
ENSMUST00000106968.1
ENSMUST00000106967.1
leucine rich repeat containing 51
chrX_+_49470450 0.98 ENSMUST00000114904.3
Rho GTPase activating protein 36
chrX_+_49470555 0.97 ENSMUST00000042444.6
Rho GTPase activating protein 36
chr6_-_12749193 0.95 ENSMUST00000046121.6
ENSMUST00000172356.1
thrombospondin, type I, domain containing 7A
chr1_+_51289106 0.95 ENSMUST00000051572.6
serum deprivation response
chr4_+_108460000 0.94 ENSMUST00000097925.2
zinc finger, CCHC domain containing 11
chr2_+_3713478 0.94 ENSMUST00000115053.2
family with sequence similarity 107, member B
chr4_+_11579647 0.94 ENSMUST00000180239.1
fibrinogen silencer binding protein
chr2_-_152398046 0.92 ENSMUST00000063332.8
ENSMUST00000182625.1
SRY-box containing gene 12
chr12_-_34528844 0.91 ENSMUST00000110819.2
histone deacetylase 9
chr2_+_3713449 0.91 ENSMUST00000027965.4
family with sequence similarity 107, member B
chr2_-_26208281 0.90 ENSMUST00000054099.9
LIM homeobox protein 3
chr1_+_66386968 0.90 ENSMUST00000145419.1
microtubule-associated protein 2
chr8_-_84937347 0.89 ENSMUST00000109741.2
ENSMUST00000119820.1
microtubule associated serine/threonine kinase 1
chr3_+_101377074 0.89 ENSMUST00000043983.5
immunoglobulin superfamily, member 3
chrX_-_23285532 0.89 ENSMUST00000115319.2
kelch-like 13
chr7_+_92819892 0.89 ENSMUST00000107180.1
ENSMUST00000107179.1
RAB30, member RAS oncogene family
chr5_-_138171216 0.89 ENSMUST00000147920.1
minichromosome maintenance deficient 7 (S. cerevisiae)
chr1_-_12991109 0.88 ENSMUST00000115403.2
ENSMUST00000115402.1
solute carrier organic anion transporter family, member 5A1
chr16_-_95459245 0.88 ENSMUST00000176345.1
ENSMUST00000121809.2
ENSMUST00000118113.1
ENSMUST00000122199.1
avian erythroblastosis virus E-26 (v-ets) oncogene related
chr9_-_48835932 0.86 ENSMUST00000093852.3
zinc finger and BTB domain containing 16
chr2_+_92185438 0.86 ENSMUST00000128781.2
PHD finger protein 21A
chr3_+_129532386 0.85 ENSMUST00000071402.2
ELOVL family member 6, elongation of long chain fatty acids (yeast)
chr1_+_187997835 0.83 ENSMUST00000110938.1
estrogen-related receptor gamma
chr1_+_187997821 0.83 ENSMUST00000027906.6
estrogen-related receptor gamma
chr1_+_158362330 0.82 ENSMUST00000170718.1
astrotactin 1
chr17_-_35838259 0.81 ENSMUST00000001566.8
tubulin, beta 5 class I
chr9_+_27790947 0.80 ENSMUST00000115243.2
opioid binding protein/cell adhesion molecule-like
chr1_-_64121389 0.79 ENSMUST00000055001.3
Kruppel-like factor 7 (ubiquitous)
chr3_-_33082004 0.79 ENSMUST00000108225.3
peroxisomal biogenesis factor 5-like
chr6_+_134035691 0.77 ENSMUST00000081028.6
ENSMUST00000111963.1
ets variant gene 6 (TEL oncogene)
chr2_+_124610573 0.76 ENSMUST00000103239.3
ENSMUST00000103240.2
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
chr14_+_116925379 0.76 ENSMUST00000088483.3
glypican 6
chr19_+_53329413 0.76 ENSMUST00000025998.7
Max interacting protein 1
chr10_-_68278713 0.75 ENSMUST00000020106.7
AT rich interactive domain 5B (MRF1-like)
chr6_-_136781718 0.75 ENSMUST00000078095.6
ENSMUST00000032338.7
guanylate cyclase 2c
chr4_-_91376433 0.75 ENSMUST00000107109.2
ENSMUST00000107111.2
ENSMUST00000107120.1
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr6_-_52165413 0.75 ENSMUST00000014848.8
homeobox A2
chr4_-_91376490 0.74 ENSMUST00000107124.3
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr7_-_101921175 0.73 ENSMUST00000098236.2
leucine rich repeat containing 51
chr15_+_83779999 0.73 ENSMUST00000046168.5
metallophosphoesterase domain containing 1
chr9_-_32541589 0.72 ENSMUST00000016231.7
Friend leukemia integration 1
chr4_+_13743424 0.72 ENSMUST00000006761.3
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr1_-_133921393 0.71 ENSMUST00000048432.5
proline arginine-rich end leucine-rich repeat
chr6_+_15196949 0.71 ENSMUST00000151301.1
ENSMUST00000131414.1
ENSMUST00000140557.1
ENSMUST00000115469.1
forkhead box P2
chr9_+_22099271 0.71 ENSMUST00000001384.4
calponin 1
chr2_+_4882204 0.70 ENSMUST00000115019.1
selenophosphate synthetase 1
chr4_-_116405986 0.69 ENSMUST00000123072.1
ENSMUST00000144281.1
microtubule associated serine/threonine kinase 2
chr1_+_87404916 0.69 ENSMUST00000173152.1
ENSMUST00000173663.1
GRB10 interacting GYF protein 2
chr1_-_119837613 0.65 ENSMUST00000064091.5
protein tyrosine phosphatase, non-receptor type 4
chr4_-_83486178 0.65 ENSMUST00000130626.1
PC4 and SFRS1 interacting protein 1
chr11_-_102026924 0.64 ENSMUST00000107167.1
ENSMUST00000062801.4
membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
chr2_+_181763315 0.63 ENSMUST00000081125.4
myelin transcription factor 1
chr14_+_45219993 0.62 ENSMUST00000146150.1
G protein-coupled receptor 137C
chr16_-_16560046 0.62 ENSMUST00000172181.2
FYVE, RhoGEF and PH domain containing 4
chr6_+_122513676 0.62 ENSMUST00000142896.1
ENSMUST00000121656.1
microfibrillar associated protein 5
chr19_-_41848076 0.62 ENSMUST00000059231.2
frequently rearranged in advanced T cell lymphomas 2
chr2_-_65567505 0.60 ENSMUST00000100069.2
sodium channel, voltage-gated, type III, alpha
chr3_+_37639945 0.60 ENSMUST00000108109.1
ENSMUST00000038569.1
sprouty homolog 1 (Drosophila)
chr3_+_37639985 0.59 ENSMUST00000108107.1
sprouty homolog 1 (Drosophila)
chr18_+_69344503 0.59 ENSMUST00000114985.3
transcription factor 4
chr12_-_71136611 0.59 ENSMUST00000021486.8
ENSMUST00000166120.1
translocase of inner mitochondrial membrane 9
chr1_+_6730051 0.58 ENSMUST00000043578.6
ENSMUST00000131467.1
ENSMUST00000150761.1
ENSMUST00000151281.1
suppression of tumorigenicity 18
chr4_+_109343029 0.58 ENSMUST00000030281.5
epidermal growth factor receptor pathway substrate 15
chr10_-_128704978 0.57 ENSMUST00000026416.7
ENSMUST00000026415.7
cyclin-dependent kinase 2
chr5_+_31251678 0.56 ENSMUST00000054829.7
ENSMUST00000114570.1
ENSMUST00000075611.7
keratinocyte associated protein 3
chr12_-_101819048 0.56 ENSMUST00000021603.8
fibulin 5
chr7_+_24907618 0.56 ENSMUST00000151121.1
Rho guanine nucleotide exchange factor (GEF) 1
chr9_-_72111172 0.55 ENSMUST00000183992.1
transcription factor 12
chr19_-_46039621 0.55 ENSMUST00000056931.7
LIM domain binding 1
chrX_+_71555918 0.55 ENSMUST00000072699.6
ENSMUST00000114582.2
ENSMUST00000015361.4
ENSMUST00000088874.3
high mobility group box 3
chr5_+_65348386 0.53 ENSMUST00000031096.7
klotho beta
chr2_-_62573813 0.53 ENSMUST00000174234.1
ENSMUST00000000402.9
ENSMUST00000174448.1
fibroblast activation protein
chr13_+_44840686 0.53 ENSMUST00000173906.1
jumonji, AT rich interactive domain 2
chr1_-_158356258 0.53 ENSMUST00000004133.8
bone morphogenic protein/retinoic acid inducible neural-specific 2
chr2_-_65567465 0.53 ENSMUST00000066432.5
sodium channel, voltage-gated, type III, alpha
chr1_+_135232045 0.52 ENSMUST00000110798.3
predicted gene 4204
chr14_-_89898466 0.51 ENSMUST00000081204.4
predicted gene 10110
chr7_+_126760591 0.51 ENSMUST00000091328.2
mitogen-activated protein kinase 3
chr11_-_3863895 0.50 ENSMUST00000070552.7
oxysterol binding protein 2
chr13_-_115101909 0.49 ENSMUST00000061673.7
integrin alpha 1
chr15_-_77153772 0.48 ENSMUST00000166610.1
ENSMUST00000111581.2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr12_+_51348265 0.47 ENSMUST00000119211.1
G2/M-phase specific E3 ubiquitin ligase
chr1_-_97761538 0.46 ENSMUST00000171129.1
diphosphoinositol pentakisphosphate kinase 2
chr4_-_83486453 0.46 ENSMUST00000107214.2
ENSMUST00000107215.2
ENSMUST00000030207.8
PC4 and SFRS1 interacting protein 1
chr10_-_18234930 0.46 ENSMUST00000052648.8
ENSMUST00000080860.6
ENSMUST00000173243.1
coiled-coil domain containing 28A
chr13_+_99100698 0.45 ENSMUST00000181742.1
predicted gene 807
chr4_+_118620799 0.45 ENSMUST00000030501.8
EBNA1 binding protein 2
chr9_+_70207342 0.45 ENSMUST00000034745.7
myosin IE
chr4_+_123282778 0.45 ENSMUST00000106243.1
ENSMUST00000106241.1
ENSMUST00000080178.6
poly(A) binding protein, cytoplasmic 4
chrM_+_7759 0.45 ENSMUST00000082407.1
ENSMUST00000082408.1
mitochondrially encoded ATP synthase 8
mitochondrially encoded ATP synthase 6
chr17_+_12584183 0.44 ENSMUST00000046959.7
solute carrier family 22 (organic cation transporter), member 2
chrX_+_163911401 0.44 ENSMUST00000140845.1
adaptor-related protein complex 1, sigma 2 subunit
chr13_+_44731281 0.44 ENSMUST00000174086.1
jumonji, AT rich interactive domain 2
chr2_+_65620829 0.44 ENSMUST00000028377.7
sodium channel, voltage-gated, type II, alpha 1
chr2_+_153031852 0.44 ENSMUST00000037235.6
X Kell blood group precursor related family member 7 homolog
chr8_-_56550791 0.44 ENSMUST00000134162.1
ENSMUST00000140107.1
ENSMUST00000040330.8
ENSMUST00000135337.1
centrosomal protein 44
chr12_-_72236692 0.44 ENSMUST00000021497.9
ENSMUST00000137990.1
reticulon 1
chr16_-_17125106 0.44 ENSMUST00000093336.6
RIKEN cDNA 2610318N02 gene
chr15_+_99702278 0.43 ENSMUST00000023759.4
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
chr2_+_3114220 0.43 ENSMUST00000072955.5
family with sequence similarity 171, member A1
chr2_-_62573905 0.43 ENSMUST00000102732.3
fibroblast activation protein
chr13_-_40733768 0.41 ENSMUST00000110193.2
transcription factor AP-2, alpha
chr15_-_76243401 0.41 ENSMUST00000165738.1
ENSMUST00000075689.6
poly (ADP-ribose) polymerase family, member 10
chr12_+_100779055 0.41 ENSMUST00000069782.4
RIKEN cDNA 9030617O03 gene
chr5_+_42067960 0.40 ENSMUST00000087332.4
predicted gene 16223
chr2_+_31670714 0.40 ENSMUST00000038474.7
ENSMUST00000137156.1
exosome component 2
chr1_-_165934900 0.39 ENSMUST00000069609.5
ENSMUST00000111427.2
ENSMUST00000111426.4
POU domain, class 2, transcription factor 1
chr7_+_82175156 0.39 ENSMUST00000180243.1
SH3-domain GRB2-like 3
chr12_+_100779074 0.39 ENSMUST00000110073.1
ENSMUST00000110070.1
RIKEN cDNA 9030617O03 gene
chr11_-_5950018 0.39 ENSMUST00000102920.3
glucokinase
chr4_-_103215147 0.39 ENSMUST00000150285.1
solute carrier family 35 (UDP-glucuronic acid/UDP-N-acetylgalactosamine dual transporter), member D1
chr7_+_119900099 0.38 ENSMUST00000106516.1
LYR motif containing 1
chr12_+_100779088 0.38 ENSMUST00000110069.1
RIKEN cDNA 9030617O03 gene
chr9_-_29411736 0.37 ENSMUST00000115236.1
neurotrimin
chr10_+_116301374 0.37 ENSMUST00000092167.5
protein tyrosine phosphatase, receptor type, B
chr9_+_122923050 0.37 ENSMUST00000051667.7
ENSMUST00000148851.1
zinc finger protein 105
chr3_+_18054258 0.36 ENSMUST00000026120.6
basic helix-loop-helix family, member e22
chr3_+_26331150 0.36 ENSMUST00000099182.2
RIKEN cDNA A830092H15 gene
chr6_-_3494587 0.36 ENSMUST00000049985.8
HEPACAM family member 2
chr7_-_127876777 0.36 ENSMUST00000106262.1
ENSMUST00000106263.1
ENSMUST00000054415.5
zinc finger protein 668
chr18_-_75697639 0.36 ENSMUST00000165559.1
CBP80/20-dependent translation initiation factor
chr4_+_86053887 0.36 ENSMUST00000107178.2
ENSMUST00000048885.5
ENSMUST00000141889.1
ENSMUST00000120678.1
ADAMTS-like 1
chr6_+_122513643 0.36 ENSMUST00000118626.1
microfibrillar associated protein 5
chr17_+_46646225 0.35 ENSMUST00000002844.7
ENSMUST00000113429.1
ENSMUST00000113430.1
mitochondrial ribosomal protein L2
chr4_-_135873546 0.35 ENSMUST00000142585.1
proline-rich nuclear receptor coactivator 2
chr12_+_51348370 0.35 ENSMUST00000121521.1
G2/M-phase specific E3 ubiquitin ligase
chr15_-_10713537 0.35 ENSMUST00000090339.3
retinoic acid induced 14
chr9_+_74976096 0.34 ENSMUST00000081746.5
family with sequence similarity 214, member A
chr4_-_82505749 0.33 ENSMUST00000107245.2
ENSMUST00000107246.1
nuclear factor I/B
chr6_-_120364344 0.33 ENSMUST00000146667.1
coiled-coil domain containing 77
chr6_-_113934679 0.33 ENSMUST00000101044.2
ATPase, Ca++ transporting, plasma membrane 2
chrX_-_12128386 0.32 ENSMUST00000145872.1
BCL6 interacting corepressor
chr4_+_115059507 0.32 ENSMUST00000162489.1
T cell acute lymphocytic leukemia 1
chr5_+_65131184 0.32 ENSMUST00000031089.5
ENSMUST00000101191.3
kelch-like 5
chr13_+_108860072 0.31 ENSMUST00000177907.1
phosphodiesterase 4D, cAMP specific
chr6_+_42264983 0.31 ENSMUST00000031895.6
caspase 2
chr12_-_99393010 0.31 ENSMUST00000177451.1
forkhead box N3
chr7_+_127876796 0.31 ENSMUST00000131000.1
zinc finger protein 646
chr14_+_54936456 0.30 ENSMUST00000037814.6
CKLF-like MARVEL transmembrane domain containing 5
chr9_-_60838200 0.30 ENSMUST00000063858.7
predicted gene 9869
chr15_+_101266839 0.30 ENSMUST00000023779.6
nuclear receptor subfamily 4, group A, member 1
chr10_+_69534208 0.29 ENSMUST00000182439.1
ENSMUST00000092434.5
ENSMUST00000092432.5
ENSMUST00000092431.5
ENSMUST00000054167.8
ENSMUST00000047061.6
ankyrin 3, epithelial

Network of associatons between targets according to the STRING database.

First level regulatory network of Sox5_Sry

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 6.7 GO:0030824 negative regulation of cGMP metabolic process(GO:0030824) negative regulation of cGMP biosynthetic process(GO:0030827) negative regulation of guanylate cyclase activity(GO:0031283)
1.0 3.0 GO:0042271 unidimensional cell growth(GO:0009826) susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.9 7.4 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.8 5.0 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.7 7.6 GO:2000980 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.6 2.6 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.6 4.4 GO:0042320 negative regulation of synaptic transmission, dopaminergic(GO:0032227) regulation of circadian sleep/wake cycle, REM sleep(GO:0042320) circadian sleep/wake cycle, REM sleep(GO:0042747)
0.6 2.4 GO:1900739 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.5 4.6 GO:0010587 miRNA catabolic process(GO:0010587)
0.5 2.0 GO:0014732 skeletal muscle atrophy(GO:0014732)
0.5 2.8 GO:1903054 negative regulation of extracellular matrix organization(GO:1903054)
0.3 3.1 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.3 0.9 GO:0021526 medial motor column neuron differentiation(GO:0021526)
0.2 2.9 GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.2 1.2 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.2 2.5 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.2 1.1 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.2 1.1 GO:0046684 response to pyrethroid(GO:0046684)
0.2 5.2 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.2 1.1 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.2 1.4 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.2 1.5 GO:0014807 regulation of somitogenesis(GO:0014807)
0.2 2.1 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.2 0.6 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.1 0.7 GO:0021658 rhombomere 3 morphogenesis(GO:0021658)
0.1 0.7 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.1 2.0 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.1 0.9 GO:0042078 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.1 0.4 GO:2000616 negative regulation of histone H3-K9 acetylation(GO:2000616)
0.1 1.1 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.1 0.5 GO:0043973 histone H3-K4 acetylation(GO:0043973)
0.1 0.4 GO:0021623 oculomotor nerve morphogenesis(GO:0021622) oculomotor nerve formation(GO:0021623)
0.1 0.4 GO:1902915 negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915)
0.1 1.8 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.1 0.5 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.1 1.6 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.1 0.5 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.1 1.1 GO:0097475 motor neuron migration(GO:0097475)
0.1 1.8 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.1 0.6 GO:0032298 positive regulation of DNA-dependent DNA replication initiation(GO:0032298)
0.1 0.8 GO:0007296 vitellogenesis(GO:0007296)
0.1 0.5 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.1 0.3 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.1 0.4 GO:0071051 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043) polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.1 0.8 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
0.1 0.3 GO:1903659 transforming growth factor beta activation(GO:0036363) regulation of complement-dependent cytotoxicity(GO:1903659) negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.1 2.0 GO:1900746 regulation of vascular endothelial growth factor signaling pathway(GO:1900746)
0.1 0.9 GO:0030035 microspike assembly(GO:0030035)
0.1 0.5 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.1 0.3 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.1 0.9 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.1 0.4 GO:0035166 post-embryonic hemopoiesis(GO:0035166)
0.1 0.7 GO:1904706 negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.1 0.2 GO:1990523 bone regeneration(GO:1990523)
0.1 0.5 GO:0000189 MAPK import into nucleus(GO:0000189)
0.1 0.3 GO:0032474 otolith morphogenesis(GO:0032474)
0.1 0.8 GO:0060613 fat pad development(GO:0060613)
0.1 0.2 GO:0031064 negative regulation of histone deacetylation(GO:0031064)
0.1 0.2 GO:0045643 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.1 0.2 GO:0014870 response to inactivity(GO:0014854) response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.1 0.6 GO:0071698 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.1 1.0 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.1 1.9 GO:0097435 fibril organization(GO:0097435)
0.1 0.4 GO:0009730 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.1 3.3 GO:0048745 smooth muscle tissue development(GO:0048745)
0.1 0.3 GO:0048691 regulation of sprouting of injured axon(GO:0048686) positive regulation of sprouting of injured axon(GO:0048687) regulation of axon extension involved in regeneration(GO:0048690) positive regulation of axon extension involved in regeneration(GO:0048691)
0.1 1.2 GO:0035988 chondrocyte proliferation(GO:0035988)
0.1 1.5 GO:0008090 retrograde axonal transport(GO:0008090)
0.1 0.8 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 0.3 GO:0016240 autophagosome docking(GO:0016240)
0.1 0.1 GO:0098928 presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
0.1 0.2 GO:0033128 positive regulation of reciprocal meiotic recombination(GO:0010845) negative regulation of histone phosphorylation(GO:0033128)
0.1 0.2 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.1 0.6 GO:2000121 regulation of removal of superoxide radicals(GO:2000121)
0.1 0.4 GO:0021960 anterior commissure morphogenesis(GO:0021960)
0.1 0.2 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.1 0.2 GO:2001015 negative regulation of skeletal muscle cell differentiation(GO:2001015)
0.1 0.6 GO:0019065 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.1 0.5 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.1 0.9 GO:0032808 lacrimal gland development(GO:0032808)
0.1 2.7 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.1 0.2 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.1 0.7 GO:0045075 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.1 0.1 GO:0035441 cell migration involved in vasculogenesis(GO:0035441)
0.1 0.2 GO:1901536 negative regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045869) regulation of DNA demethylation(GO:1901535) negative regulation of DNA demethylation(GO:1901536)
0.0 0.2 GO:0007113 endomitotic cell cycle(GO:0007113)
0.0 1.0 GO:0031424 keratinization(GO:0031424)
0.0 1.0 GO:0048665 neuron fate specification(GO:0048665)
0.0 0.5 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.1 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.0 0.2 GO:0048014 Tie signaling pathway(GO:0048014)
0.0 0.2 GO:0060605 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0 0.6 GO:0060539 diaphragm development(GO:0060539)
0.0 0.3 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.0 0.1 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.0 1.6 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.3 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.0 GO:0010593 negative regulation of lamellipodium assembly(GO:0010593)
0.0 0.1 GO:0001928 regulation of exocyst assembly(GO:0001928)
0.0 0.1 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
0.0 0.2 GO:0032290 peripheral nervous system myelin formation(GO:0032290)
0.0 0.2 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.4 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.2 GO:2000304 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.0 0.1 GO:0046294 formaldehyde catabolic process(GO:0046294)
0.0 0.2 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.0 0.3 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.2 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.0 0.7 GO:0001967 suckling behavior(GO:0001967)
0.0 0.2 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.0 0.1 GO:0060903 positive regulation of meiosis I(GO:0060903)
0.0 0.7 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.0 0.1 GO:1903027 regulation of opsonization(GO:1903027) positive regulation of opsonization(GO:1903028)
0.0 0.7 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.1 GO:0015770 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.0 0.4 GO:0015697 quaternary ammonium group transport(GO:0015697)
0.0 0.4 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 2.0 GO:0006940 regulation of smooth muscle contraction(GO:0006940)
0.0 0.1 GO:0031161 phosphatidylinositol catabolic process(GO:0031161)
0.0 0.1 GO:0007144 female meiosis I(GO:0007144)
0.0 0.8 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
0.0 0.1 GO:0002727 natural killer cell cytokine production(GO:0002370) regulation of natural killer cell cytokine production(GO:0002727)
0.0 0.7 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.2 GO:0038031 non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.0 0.1 GO:0060368 regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060368)
0.0 0.2 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.0 0.9 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.0 0.2 GO:1903142 blood vessel maturation(GO:0001955) positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.0 0.1 GO:0010986 positive regulation of lipoprotein particle clearance(GO:0010986)
0.0 0.1 GO:0050904 diapedesis(GO:0050904)
0.0 0.2 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.2 GO:0033184 positive regulation of histone ubiquitination(GO:0033184)
0.0 0.0 GO:1905063 regulation of vascular smooth muscle cell differentiation(GO:1905063)
0.0 0.1 GO:0061146 Peyer's patch morphogenesis(GO:0061146)
0.0 0.2 GO:0070914 UV-damage excision repair(GO:0070914)
0.0 0.5 GO:0042311 vasodilation(GO:0042311)
0.0 0.1 GO:1901837 negative regulation of transcription from RNA polymerase I promoter(GO:0016479) negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837)
0.0 1.6 GO:0051225 spindle assembly(GO:0051225)
0.0 0.2 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 0.2 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 0.9 GO:0021510 spinal cord development(GO:0021510)
0.0 0.1 GO:1902965 regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966)
0.0 2.9 GO:0007411 axon guidance(GO:0007411)
0.0 0.1 GO:0035095 behavioral response to nicotine(GO:0035095)
0.0 0.4 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.2 GO:0014823 response to activity(GO:0014823)
0.0 0.1 GO:0048102 autophagic cell death(GO:0048102)
0.0 0.2 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0 1.7 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.1 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 0.2 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.4 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.0 0.2 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0 0.3 GO:0033137 negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.0 0.3 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495) antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504)
0.0 1.5 GO:1990830 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.0 0.4 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 5.0 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.5 6.7 GO:0044327 dendritic spine head(GO:0044327)
0.3 1.5 GO:0031673 H zone(GO:0031673)
0.2 2.1 GO:0030478 actin cap(GO:0030478)
0.2 3.1 GO:0042555 MCM complex(GO:0042555)
0.2 3.0 GO:0070852 cell body fiber(GO:0070852)
0.2 0.6 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
0.2 1.9 GO:0045298 tubulin complex(GO:0045298)
0.1 0.6 GO:0071953 elastic fiber(GO:0071953)
0.1 2.2 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.1 1.8 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 1.0 GO:0071438 invadopodium membrane(GO:0071438)
0.1 0.6 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.1 2.5 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 0.8 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.1 0.3 GO:0033193 Lsd1/2 complex(GO:0033193)
0.1 0.9 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.1 0.4 GO:0032437 cuticular plate(GO:0032437)
0.1 1.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 1.0 GO:0001533 cornified envelope(GO:0001533)
0.1 1.1 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 0.3 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 0.4 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.1 1.1 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.1 0.7 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.3 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.1 GO:0044317 rod spherule(GO:0044317)
0.0 2.8 GO:0032420 stereocilium(GO:0032420)
0.0 1.1 GO:0030673 axolemma(GO:0030673)
0.0 0.6 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 0.2 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.1 GO:0042585 germinal vesicle(GO:0042585)
0.0 1.2 GO:0031985 Golgi cisterna(GO:0031985)
0.0 0.4 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.2 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.8 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.2 GO:0042382 paraspeckles(GO:0042382)
0.0 0.2 GO:0033503 HULC complex(GO:0033503)
0.0 0.3 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.5 GO:0031143 pseudopodium(GO:0031143)
0.0 0.5 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.4 GO:0045180 basal cortex(GO:0045180)
0.0 0.1 GO:0044305 calyx of Held(GO:0044305)
0.0 0.1 GO:0034657 GID complex(GO:0034657)
0.0 0.6 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 7.9 GO:0000139 Golgi membrane(GO:0000139)
0.0 2.5 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 3.3 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.2 GO:0031011 Ino80 complex(GO:0031011)
0.0 0.6 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 0.6 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.0 0.8 GO:1990391 DNA repair complex(GO:1990391)
0.0 0.9 GO:0035097 histone methyltransferase complex(GO:0035097)
0.0 0.2 GO:0034709 methylosome(GO:0034709)
0.0 0.1 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 2.5 GO:0032993 protein-DNA complex(GO:0032993)
0.0 0.5 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.2 GO:0032433 filopodium tip(GO:0032433)
0.0 0.1 GO:0000923 equatorial microtubule organizing center(GO:0000923)
0.0 0.5 GO:0008305 integrin complex(GO:0008305)
0.0 1.3 GO:0005581 collagen trimer(GO:0005581)
0.0 0.5 GO:0097440 apical dendrite(GO:0097440)
0.0 0.1 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.1 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 8.0 GO:0005815 microtubule organizing center(GO:0005815)
0.0 0.1 GO:1990130 Iml1 complex(GO:1990130)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 5.3 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.6 2.5 GO:0047288 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836) monosialoganglioside sialyltransferase activity(GO:0047288)
0.5 2.2 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.5 2.0 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.5 7.2 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.3 1.0 GO:0030280 structural constituent of epidermis(GO:0030280)
0.3 1.1 GO:0097100 supercoiled DNA binding(GO:0097100)
0.3 1.3 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.2 1.0 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.2 1.1 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.2 1.1 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.2 0.2 GO:0035851 Krueppel-associated box domain binding(GO:0035851)
0.2 4.4 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.1 0.4 GO:0005333 norepinephrine transmembrane transporter activity(GO:0005333)
0.1 0.8 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.1 0.9 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.1 1.9 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.1 0.5 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.1 2.0 GO:0008432 JUN kinase binding(GO:0008432)
0.1 1.4 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.1 1.2 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 0.7 GO:0061665 SUMO ligase activity(GO:0061665)
0.1 0.5 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.1 1.9 GO:0042288 MHC class I protein binding(GO:0042288)
0.1 1.1 GO:0050897 cobalt ion binding(GO:0050897)
0.1 3.1 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.1 0.3 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.1 1.0 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.1 1.1 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.1 1.6 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.1 0.8 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 0.2 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.1 1.2 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.3 GO:0002135 CTP binding(GO:0002135)
0.0 0.3 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.0 0.1 GO:0018738 S-formylglutathione hydrolase activity(GO:0018738)
0.0 0.5 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.2 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.0 0.1 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211)
0.0 0.7 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.4 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 7.4 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds(GO:0016810)
0.0 0.2 GO:0008761 UDP-N-acetylglucosamine 2-epimerase activity(GO:0008761)
0.0 0.3 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.2 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.4 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396)
0.0 0.9 GO:0031402 sodium ion binding(GO:0031402)
0.0 0.7 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.3 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.1 GO:0019237 centromeric DNA binding(GO:0019237)
0.0 2.3 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.6 GO:0035173 histone kinase activity(GO:0035173)
0.0 0.1 GO:0008515 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.0 0.5 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.8 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.7 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 2.1 GO:0005518 collagen binding(GO:0005518)
0.0 1.7 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 2.6 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.8 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.2 GO:0045322 unmethylated CpG binding(GO:0045322)
0.0 0.4 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 2.6 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.0 0.1 GO:0008934 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.0 0.2 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.3 GO:0042287 MHC protein binding(GO:0042287)
0.0 1.5 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 2.4 GO:0051117 ATPase binding(GO:0051117)
0.0 0.4 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.5 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.9 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.3 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.2 GO:0001727 lipid kinase activity(GO:0001727)
0.0 0.2 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.0 0.2 GO:0003678 DNA helicase activity(GO:0003678)
0.0 0.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.2 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.3 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.1 GO:0005522 profilin binding(GO:0005522)
0.0 0.1 GO:0035473 lipase binding(GO:0035473)
0.0 1.0 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.1 GO:0042166 acetylcholine binding(GO:0042166)
0.0 0.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 7.0 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.0 GO:0051022 Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0 0.2 GO:0001671 ATPase activator activity(GO:0001671)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 8.0 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.1 5.3 PID ATR PATHWAY ATR signaling pathway
0.1 2.3 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 3.6 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 4.6 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 1.1 PID BARD1 PATHWAY BARD1 signaling events
0.0 2.8 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 1.4 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.2 PID IL5 PATHWAY IL5-mediated signaling events
0.0 1.3 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.9 PID AURORA B PATHWAY Aurora B signaling
0.0 0.3 PID AP1 PATHWAY AP-1 transcription factor network
0.0 2.7 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 0.2 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.5 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.2 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 2.4 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.2 PID EPHRINB REV PATHWAY Ephrin B reverse signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 6.4 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.2 3.1 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.2 6.0 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.1 1.1 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1 2.5 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 2.5 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 0.7 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 2.6 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 2.5 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 2.2 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 2.0 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1 0.6 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.4 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.7 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 1.2 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 1.3 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.4 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.8 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.4 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 4.4 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.4 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.3 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.8 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.6 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.3 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.3 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 1.7 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 1.3 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 1.9 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.5 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 0.3 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 0.7 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 2.4 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.3 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 1.3 REACTOME EXTRACELLULAR MATRIX ORGANIZATION Genes involved in Extracellular matrix organization
0.0 0.2 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.1 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.1 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.3 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.3 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.1 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.6 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.7 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.1 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling