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12D miR HR13_24

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Results for Arid5b

Z-value: 0.55

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Transcription factors associated with Arid5b

Gene Symbol Gene ID Gene Info
ENSMUSG00000019947.9 AT rich interactive domain 5B (MRF1-like)

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Arid5bmm10_v2_chr10_-_68278713_682787350.749.4e-03Click!

Activity profile of Arid5b motif

Sorted Z-values of Arid5b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr8_-_13254154 0.91 ENSMUST00000033825.4
ADP-ribosylhydrolase like 1
chr8_-_62123106 0.83 ENSMUST00000034052.6
ENSMUST00000034054.7
annexin A10
chr8_-_13254068 0.78 ENSMUST00000168498.1
ADP-ribosylhydrolase like 1
chr7_-_44974781 0.66 ENSMUST00000063761.7
carnitine palmitoyltransferase 1c
chr2_-_110761564 0.58 ENSMUST00000140777.1
anoctamin 3
chr18_+_62662108 0.54 ENSMUST00000163259.1
predicted gene, 17732
chr5_+_92387846 0.53 ENSMUST00000138687.1
ENSMUST00000124509.1
ADP-ribosyltransferase 3
chr14_-_47394253 0.48 ENSMUST00000177822.1
discs, large (Drosophila) homolog-associated protein 5
chr7_-_101921186 0.42 ENSMUST00000106965.1
ENSMUST00000106968.1
ENSMUST00000106967.1
leucine rich repeat containing 51
chr8_-_13254096 0.39 ENSMUST00000171619.1
ADP-ribosylhydrolase like 1
chr1_+_87594545 0.39 ENSMUST00000165109.1
ENSMUST00000070898.5
neuraminidase 2
chr18_+_23415400 0.37 ENSMUST00000115832.2
ENSMUST00000047954.7
dystrobrevin alpha
chr6_+_120666388 0.36 ENSMUST00000112686.1
cat eye syndrome chromosome region, candidate 2
chr5_+_92387673 0.35 ENSMUST00000145072.1
ADP-ribosyltransferase 3
chr6_+_40493592 0.34 ENSMUST00000038750.5
taste receptor, type 2, member 108
chr7_-_67645195 0.33 ENSMUST00000032775.5
ENSMUST00000053950.2
leucine rich repeat containing 28
chrX_-_157492280 0.29 ENSMUST00000112529.1
spermine synthase
chr2_-_160313616 0.26 ENSMUST00000109475.2
predicted gene 826
chr16_+_56477838 0.25 ENSMUST00000048471.7
ENSMUST00000096013.3
ENSMUST00000096012.3
ENSMUST00000171000.1
ABI gene family, member 3 (NESH) binding protein
chr16_+_57353093 0.25 ENSMUST00000159816.1
filamin A interacting protein 1-like
chr12_-_91746020 0.25 ENSMUST00000166967.1
stonin 2
chr13_-_98694825 0.24 ENSMUST00000064347.7
transmembrane protein 171
chr15_-_55548164 0.23 ENSMUST00000165356.1
mitochondrial ribosomal protein L13
chr1_+_180568913 0.22 ENSMUST00000027777.6
poly (ADP-ribose) polymerase family, member 1
chr7_+_107567445 0.22 ENSMUST00000120990.1
olfactomedin-like 1
chr11_+_98383811 0.21 ENSMUST00000008021.2
titin-cap
chr8_+_34115030 0.21 ENSMUST00000095345.3
membrane bound O-acyltransferase domain containing 4
chr5_+_31297551 0.21 ENSMUST00000072228.5
glucokinase regulatory protein
chr2_+_76650264 0.20 ENSMUST00000099986.2
deafness, autosomal recessive 59 (human)
chr2_+_25180737 0.20 ENSMUST00000104999.2
Notch-regulated ankyrin repeat protein
chr9_+_21196705 0.20 ENSMUST00000003395.9
phosphodiesterase 4A, cAMP specific
chr14_-_23650189 0.20 ENSMUST00000112423.3
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr7_-_89633124 0.20 ENSMUST00000172178.1
RIKEN cDNA A230065N10 gene
chr3_+_51559757 0.19 ENSMUST00000180616.1
RIKEN cDNA 5031434O11 gene
chr17_+_71019548 0.19 ENSMUST00000073211.5
ENSMUST00000179759.1
myomesin 1
chr11_-_3193388 0.19 ENSMUST00000081318.6
ENSMUST00000142315.1
ENSMUST00000118627.1
ENSMUST00000066391.7
Sfi1 homolog, spindle assembly associated (yeast)
chrX_-_150812932 0.17 ENSMUST00000131241.1
ENSMUST00000147152.1
ENSMUST00000143843.1
melanoma antigen, family D, 2
chr13_+_109685994 0.16 ENSMUST00000074103.5
phosphodiesterase 4D, cAMP specific
chr17_+_71019503 0.15 ENSMUST00000024847.7
myomesin 1
chr11_-_50827681 0.14 ENSMUST00000109135.2
zinc finger protein 354C
chr3_-_95882031 0.13 ENSMUST00000161994.1
predicted gene 129
chr1_-_173599074 0.13 ENSMUST00000150649.1
ENSMUST00000180215.1
ENSMUST00000097462.2
pyrin domain containing 4
chr14_-_52213379 0.13 ENSMUST00000140603.1
chromodomain helicase DNA binding protein 8
chr2_-_60553303 0.13 ENSMUST00000112525.2
ENSMUST00000067708.5
phospholipase A2 receptor 1
chr4_+_43493345 0.12 ENSMUST00000030181.5
ENSMUST00000107922.2
coiled-coil domain containing 107
chr5_+_115908644 0.12 ENSMUST00000141101.1
citron
chr2_-_84678828 0.11 ENSMUST00000111665.1
thioredoxin-related transmembrane protein 2
chr9_-_42457594 0.11 ENSMUST00000125995.1
tubulin folding cofactor E-like
chr3_-_95882232 0.11 ENSMUST00000161866.1
predicted gene 129
chr15_-_44428303 0.10 ENSMUST00000038719.6
NudC domain containing 1
chr9_-_45984816 0.10 ENSMUST00000172450.1
platelet-activating factor acetylhydrolase, isoform 1b, subunit 2
chr6_+_129397478 0.09 ENSMUST00000112081.2
ENSMUST00000112079.2
C-type lectin domain family 1, member b
chr9_-_42461414 0.09 ENSMUST00000066179.7
tubulin folding cofactor E-like
chr10_+_127420867 0.09 ENSMUST00000064793.6
R3H domain containing 2
chr4_+_132638987 0.08 ENSMUST00000135299.1
ENSMUST00000081726.6
ENSMUST00000180250.1
ENSMUST00000020197.7
ENSMUST00000079157.4
eyes absent 3 homolog (Drosophila)
chr15_-_13173607 0.08 ENSMUST00000036439.4
cadherin 6
chrX_+_47912387 0.08 ENSMUST00000001202.8
ENSMUST00000115020.1
oculocerebrorenal syndrome of Lowe
chr2_-_151744142 0.08 ENSMUST00000109869.1
proteasome (prosome, macropain) inhibitor subunit 1
chr10_+_94576254 0.07 ENSMUST00000117929.1
transmembrane and coiled coil domains 3
chr12_+_110601439 0.07 ENSMUST00000018851.7
dynein cytoplasmic 1 heavy chain 1
chr1_+_174172738 0.07 ENSMUST00000027817.7
spectrin alpha, erythrocytic 1
chr9_+_87022014 0.07 ENSMUST00000168529.2
ENSMUST00000174724.1
ENSMUST00000173126.1
cytochrome b5 reductase 4
chr9_+_122117338 0.06 ENSMUST00000120173.1
ENSMUST00000134949.1
ENSMUST00000119215.1
SNF related kinase
chr6_-_16898441 0.06 ENSMUST00000031533.7
transcription factor EC
chrM_+_8600 0.05 ENSMUST00000082409.1
mitochondrially encoded cytochrome c oxidase III
chr7_-_126676428 0.04 ENSMUST00000106373.1
sulfotransferase family 1A, phenol-preferring, member 1
chr3_+_103860265 0.04 ENSMUST00000029433.7
protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
chr4_-_75278246 0.04 ENSMUST00000030103.8
transmembrane protein 261
chr4_-_150909428 0.03 ENSMUST00000128075.1
ENSMUST00000105674.1
ENSMUST00000105673.1
Parkinson disease (autosomal recessive, early onset) 7
chr15_+_44428073 0.03 ENSMUST00000060652.3
enhancer of yellow 2 homolog (Drosophila)
chr4_+_105157339 0.03 ENSMUST00000064139.7
phosphatidic acid phosphatase type 2B
chr13_+_23533869 0.03 ENSMUST00000073261.2
histone cluster 1, H2af
chr8_-_79399513 0.03 ENSMUST00000066091.7
ENSMUST00000109885.1
ENSMUST00000066081.3
SMAD family member 1
chr3_-_19265007 0.03 ENSMUST00000091314.4
phosphodiesterase 7A
chr15_+_78842632 0.03 ENSMUST00000059619.1
CDC42 effector protein (Rho GTPase binding) 1
chr1_+_163779575 0.02 ENSMUST00000027877.6
ENSMUST00000077642.5
kinesin-associated protein 3
chr11_-_32267547 0.02 ENSMUST00000109389.2
ENSMUST00000129010.1
ENSMUST00000020530.5
nitrogen permease regulator-like 3
chrX_+_140456613 0.02 ENSMUST00000033809.3
phosphoribosyl pyrophosphate synthetase 1
chr8_+_104831572 0.02 ENSMUST00000059449.6
carboxyesterase 2B
chr4_-_129662442 0.01 ENSMUST00000003828.4
karyopherin (importin) alpha 6
chr18_-_15063560 0.01 ENSMUST00000168989.1
potassium channel tetramerisation domain containing 1
chr18_-_25753852 0.01 ENSMUST00000025117.6
ENSMUST00000115816.2
CUGBP, Elav-like family member 4
chr13_+_21735055 0.01 ENSMUST00000087714.4
histone cluster 1, H4j
chr2_-_84678051 0.00 ENSMUST00000053664.8
ENSMUST00000111664.1
thioredoxin-related transmembrane protein 2

Network of associatons between targets according to the STRING database.

First level regulatory network of Arid5b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.1 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.1 0.6 GO:0061591 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.1 0.2 GO:1904760 myofibroblast differentiation(GO:0036446) regulation of myofibroblast differentiation(GO:1904760)
0.1 0.4 GO:0009313 ganglioside catabolic process(GO:0006689) oligosaccharide catabolic process(GO:0009313)
0.1 0.2 GO:0009750 response to fructose(GO:0009750)
0.0 0.2 GO:1904305 negative regulation of gastro-intestinal system smooth muscle contraction(GO:1904305) negative regulation of small intestine smooth muscle contraction(GO:1904348)
0.0 0.7 GO:0009437 carnitine metabolic process(GO:0009437)
0.0 0.2 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.0 0.3 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.3 GO:0008215 spermine metabolic process(GO:0008215)
0.0 0.1 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
0.0 0.4 GO:0001842 neural fold formation(GO:0001842)
0.0 0.2 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 0.1 GO:0072382 minus-end-directed vesicle transport along microtubule(GO:0072382)
0.0 0.9 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 0.2 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 0.0 GO:0071613 positive regulation of toll-like receptor 9 signaling pathway(GO:0034165) granzyme B production(GO:0071613) regulation of granzyme B production(GO:0071661) positive regulation of granzyme B production(GO:0071663)
0.0 0.2 GO:1901844 regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.0 GO:1903185 enzyme active site formation via L-cysteine sulfinic acid(GO:0018323) primary alcohol biosynthetic process(GO:0034309) cellular response to glyoxal(GO:0036471) glycolate biosynthetic process(GO:0046295) negative regulation of TRAIL-activated apoptotic signaling pathway(GO:1903122) regulation of pyrroline-5-carboxylate reductase activity(GO:1903167) positive regulation of pyrroline-5-carboxylate reductase activity(GO:1903168) regulation of tyrosine 3-monooxygenase activity(GO:1903176) positive regulation of tyrosine 3-monooxygenase activity(GO:1903178) L-dopa metabolic process(GO:1903184) L-dopa biosynthetic process(GO:1903185) glyoxal metabolic process(GO:1903189) regulation of L-dopa biosynthetic process(GO:1903195) positive regulation of L-dopa biosynthetic process(GO:1903197) regulation of L-dopa decarboxylase activity(GO:1903198) positive regulation of L-dopa decarboxylase activity(GO:1903200) positive regulation of cellular amino acid biosynthetic process(GO:2000284)
0.0 0.1 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.1 GO:2000270 positive regulation of transcription from RNA polymerase III promoter(GO:0045945) negative regulation of fibroblast apoptotic process(GO:2000270)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0090537 CERF complex(GO:0090537)
0.0 0.5 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.2 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.3 GO:0005859 muscle myosin complex(GO:0005859)
0.0 0.3 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.7 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.3 GO:0005614 interstitial matrix(GO:0005614)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.1 GO:0003875 ADP-ribosylarginine hydrolase activity(GO:0003875)
0.1 0.7 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.1 0.4 GO:0052794 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997) exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.1 0.2 GO:0051373 FATZ binding(GO:0051373)
0.1 0.9 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 0.2 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.0 0.3 GO:0008527 taste receptor activity(GO:0008527)
0.0 0.1 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.0 0.6 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.2 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 0.2 GO:0003909 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 0.3 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.0 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.0 0.0 GO:0036478 tyrosine 3-monooxygenase activator activity(GO:0036470) L-dopa decarboxylase activator activity(GO:0036478)
0.0 0.4 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID AURORA A PATHWAY Aurora A signaling
0.0 0.7 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.2 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin