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12D miR HR13_24

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Results for Nkx3-1

Z-value: 1.37

Motif logo

Transcription factors associated with Nkx3-1

Gene Symbol Gene ID Gene Info
ENSMUSG00000022061.8 NK3 homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nkx3-1mm10_v2_chr14_+_69190638_69190691-0.757.8e-03Click!

Activity profile of Nkx3-1 motif

Sorted Z-values of Nkx3-1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chrX_+_164438039 3.31 ENSMUST00000033755.5
ankyrin repeat and SOCS box-containing 11
chr1_+_171155512 2.89 ENSMUST00000111334.1
myelin protein zero
chr19_+_58759700 2.83 ENSMUST00000026081.3
pancreatic lipase-related protein 2
chr16_+_32756336 2.48 ENSMUST00000135753.1
mucin 4
chr9_-_40962333 2.30 ENSMUST00000160120.1
RIKEN cDNA 4931429I11 gene
chr14_+_41131777 2.26 ENSMUST00000022314.3
ENSMUST00000170719.1
surfactant associated protein A1
chr4_+_104766308 2.22 ENSMUST00000031663.3
complement component 8, beta polypeptide
chr10_-_115185015 2.08 ENSMUST00000006949.8
tryptophan hydroxylase 2
chr4_+_110397764 2.02 ENSMUST00000097920.2
ENSMUST00000080744.6
ATP/GTP binding protein-like 4
chr4_+_110397661 1.91 ENSMUST00000106589.2
ENSMUST00000106587.2
ENSMUST00000106591.1
ENSMUST00000106592.1
ATP/GTP binding protein-like 4
chr9_-_62537036 1.90 ENSMUST00000048043.5
coronin, actin binding protein, 2B
chr6_+_78425973 1.85 ENSMUST00000079926.5
regenerating islet-derived 1
chr1_-_52953179 1.65 ENSMUST00000114492.1
RIKEN cDNA 1700019D03 gene
chr4_-_137409777 1.65 ENSMUST00000024200.6
predicted gene 13011
chr3_-_88027465 1.57 ENSMUST00000005014.2
hyaluronan and proteoglycan link protein 2
chr8_+_114133635 1.47 ENSMUST00000147605.1
ENSMUST00000134593.1
nudix (nucleoside diphosphate linked moiety X)-type motif 7
chr3_-_113324052 1.42 ENSMUST00000179314.1
amylase 2a3
chr10_+_69219357 1.42 ENSMUST00000172261.1
Rho-related BTB domain containing 1
chr8_+_114133557 1.41 ENSMUST00000073521.5
ENSMUST00000066514.6
nudix (nucleoside diphosphate linked moiety X)-type motif 7
chr8_+_114133601 1.32 ENSMUST00000109109.1
nudix (nucleoside diphosphate linked moiety X)-type motif 7
chr3_-_113532288 1.32 ENSMUST00000132353.1
amylase 2a1
chr4_-_137430517 1.32 ENSMUST00000102522.4
chymotrypsin-like elastase family, member 3B
chr6_-_41035501 1.29 ENSMUST00000031931.5
RIKEN cDNA 2210010C04 gene
chr18_-_6241470 1.28 ENSMUST00000163210.1
kinesin family member 5B
chr18_-_6241486 1.27 ENSMUST00000025083.7
kinesin family member 5B
chr12_-_78983476 1.27 ENSMUST00000070174.7
transmembrane protein 229B
chr1_+_171503410 1.23 ENSMUST00000081527.1
Aly/REF export factor 2
chr5_+_90367204 1.18 ENSMUST00000068250.3
predicted gene 9958
chr3_-_113291449 1.18 ENSMUST00000179568.1
amylase 2a4
chr1_-_162866502 1.17 ENSMUST00000046049.7
flavin containing monooxygenase 1
chr3_-_113356658 1.11 ENSMUST00000098667.3
amylase 2a2
chr14_-_55788810 1.11 ENSMUST00000022830.6
ENSMUST00000168716.1
ENSMUST00000178399.1
receptor-interacting serine-threonine kinase 3
chr7_-_127930066 1.11 ENSMUST00000032988.8
protease, serine, 8 (prostasin)
chr4_-_45530330 1.04 ENSMUST00000061986.5
src homology 2 domain-containing transforming protein B
chr10_+_5639210 1.01 ENSMUST00000019906.4
vasoactive intestinal polypeptide
chr3_-_113258837 0.99 ENSMUST00000098673.3
amylase 2a5
chr1_-_162478004 0.97 ENSMUST00000086074.5
ENSMUST00000070330.7
dynamin 3
chr5_+_66968416 0.97 ENSMUST00000038188.7
LIM and calponin homology domains 1
chr9_-_122310921 0.96 ENSMUST00000180685.1
predicted gene, 26797
chr12_+_59095653 0.94 ENSMUST00000021384.4
melanoma inhibitory activity 2
chr11_-_103697661 0.90 ENSMUST00000107013.2
golgi SNAP receptor complex member 2
chr9_+_108049254 0.87 ENSMUST00000112295.2
ENSMUST00000047947.7
GDP-mannose pyrophosphorylase B
chr1_+_99772765 0.86 ENSMUST00000086738.3
contactin associated protein-like 5B
chr8_+_36457548 0.86 ENSMUST00000135373.1
ENSMUST00000147525.1
RIKEN cDNA 6430573F11 gene
chr10_-_41579207 0.84 ENSMUST00000095227.3
coiled-coil domain containing 162
chr4_-_108217897 0.83 ENSMUST00000106690.1
ENSMUST00000043793.6
zyg-11 family member A, cell cycle regulator
chr17_-_79715034 0.82 ENSMUST00000024894.1
cytochrome P450, family 1, subfamily b, polypeptide 1
chr2_+_23069210 0.82 ENSMUST00000155602.1
acyl-Coenzyme A binding domain containing 5
chr4_-_140774196 0.80 ENSMUST00000026381.6
peptidyl arginine deiminase, type IV
chr1_+_157506728 0.80 ENSMUST00000086130.2
SEC16 homolog B (S. cerevisiae)
chr1_+_157506777 0.78 ENSMUST00000027881.8
SEC16 homolog B (S. cerevisiae)
chr1_-_174921813 0.78 ENSMUST00000055294.3
gremlin 2 homolog, cysteine knot superfamily (Xenopus laevis)
chr19_+_5406815 0.75 ENSMUST00000174412.1
ENSMUST00000153017.2
RIKEN cDNA 4930481A15 gene
chr7_+_12834743 0.75 ENSMUST00000004614.8
zinc finger protein 110
chrX_-_101222426 0.75 ENSMUST00000120389.1
ENSMUST00000156473.1
ENSMUST00000077876.3
sorting nexin 12
chr2_-_84715160 0.74 ENSMUST00000035840.5
zinc finger, DHHC domain containing 5
chr19_-_17356631 0.73 ENSMUST00000174236.1
glucosaminyl (N-acetyl) transferase 1, core 2
chr5_+_28071356 0.73 ENSMUST00000059155.10
insulin induced gene 1
chr8_+_47824459 0.69 ENSMUST00000038693.6
claudin 22
chr10_-_59441748 0.68 ENSMUST00000009798.4
oncoprotein induced transcript 3
chr7_-_126922887 0.64 ENSMUST00000134134.1
ENSMUST00000119781.1
ENSMUST00000121612.2
transmembrane protein 219
chr2_+_62664279 0.62 ENSMUST00000028257.2
grancalcin
chr19_+_20601958 0.61 ENSMUST00000087638.3
aldehyde dehydrogenase family 1, subfamily A1
chr13_-_99900645 0.58 ENSMUST00000022150.6
CART prepropeptide
chr17_+_37270214 0.57 ENSMUST00000038580.6
histocompatibility 2, M region locus 3
chr5_-_110046486 0.57 ENSMUST00000167969.1
predicted gene, 17655
chr4_-_129378116 0.56 ENSMUST00000030610.2
zinc finger and BTB domain containing 8a
chr12_+_52516077 0.55 ENSMUST00000110725.1
Rho GTPase activating protein 5
chr1_-_156034800 0.55 ENSMUST00000169241.1
torsin A interacting protein 1
chr7_-_121035096 0.55 ENSMUST00000065740.2
predicted gene 9905
chr5_+_8422831 0.54 ENSMUST00000066921.3
solute carrier family 25, member 40
chr19_+_4711153 0.53 ENSMUST00000008991.6
spectrin beta, non-erythrocytic 2
chr12_+_17266545 0.53 ENSMUST00000057288.5
protein disulfide isomerase associated 6
chr15_-_74997634 0.50 ENSMUST00000023248.6
lymphocyte antigen 6 complex, locus A
chr4_+_3940747 0.49 ENSMUST00000119403.1
coiled-coil-helix-coiled-coil-helix domain containing 7
chr9_+_77921908 0.48 ENSMUST00000133757.1
ELOVL family member 5, elongation of long chain fatty acids (yeast)
chr2_+_57997884 0.47 ENSMUST00000112616.1
ENSMUST00000166729.1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5
chr3_-_102782708 0.47 ENSMUST00000029450.3
ENSMUST00000172026.1
ENSMUST00000170856.1
thyroid stimulating hormone, beta subunit
chr9_+_78191966 0.46 ENSMUST00000034903.5
glutathione S-transferase, alpha 4
chr7_+_75455534 0.46 ENSMUST00000147005.1
ENSMUST00000166315.1
A kinase (PRKA) anchor protein 13
chr2_+_23068168 0.45 ENSMUST00000028121.7
ENSMUST00000114523.2
ENSMUST00000144088.1
acyl-Coenzyme A binding domain containing 5
chrX_-_100625901 0.44 ENSMUST00000059099.6
PDZ domain containing 11
chr4_-_121017201 0.44 ENSMUST00000043200.7
small ArfGAP 2
chr1_-_130452416 0.44 ENSMUST00000140400.1
CD55 antigen
chr8_+_71689214 0.44 ENSMUST00000034261.7
insulin-like 3
chr12_-_87233556 0.43 ENSMUST00000021423.7
NADP+ dependent oxidoreductase domain containing 1
chr15_-_75111684 0.42 ENSMUST00000100542.3
lymphocyte antigen 6 complex, locus C2
chr4_+_62619515 0.42 ENSMUST00000084521.4
ENSMUST00000107424.1
regulator of G-protein signaling 3
chr7_+_139214661 0.42 ENSMUST00000135509.1
leucine rich repeat containing 27
chr15_-_75048837 0.41 ENSMUST00000179762.1
ENSMUST00000065408.9
lymphocyte antigen 6 complex, locus C1
chrX_+_56454871 0.39 ENSMUST00000039374.2
ENSMUST00000101553.2
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B
chr14_-_54864055 0.38 ENSMUST00000142283.2
homeodomain leucine zipper-encoding gene
chr2_-_93849679 0.38 ENSMUST00000068513.4
ENSMUST00000041593.8
ENSMUST00000130077.1
1-aminocyclopropane-1-carboxylate synthase (non-functional)
chr14_+_79515618 0.37 ENSMUST00000110835.1
E74-like factor 1
chr15_+_100422147 0.36 ENSMUST00000132119.1
predicted gene 5475
chr11_+_118443471 0.35 ENSMUST00000133558.1
C1q and tumor necrosis factor related protein 1
chr4_+_32623985 0.35 ENSMUST00000108178.1
caspase 8 associated protein 2
chr17_+_84956718 0.33 ENSMUST00000112305.3
protein phosphatase 1B, magnesium dependent, beta isoform
chr9_+_89199319 0.33 ENSMUST00000138109.1
5, 10-methenyltetrahydrofolate synthetase
chr11_-_101278927 0.33 ENSMUST00000168089.1
ENSMUST00000017332.3
cytochrome C oxidase assembly factor 3
chr17_-_56982120 0.33 ENSMUST00000056113.4
alkaline ceramidase 1
chr5_+_72914264 0.33 ENSMUST00000144843.1
SLAIN motif family, member 2
chr2_+_132846638 0.32 ENSMUST00000028835.6
ENSMUST00000110122.3
cardiolipin synthase 1
chr3_-_64287417 0.32 ENSMUST00000170244.1
ENSMUST00000176328.1
vomeronasal 2, receptor 3
chr1_-_133907053 0.32 ENSMUST00000149380.1
ENSMUST00000124051.2
opticin
chr14_+_61309753 0.31 ENSMUST00000055159.7
ADP-ribosylation factor-like 11
chr10_-_14718191 0.31 ENSMUST00000020016.4
gap junction protein, epsilon 1
chr6_+_58833689 0.30 ENSMUST00000041401.8
hect domain and RLD 3
chr9_+_58079358 0.29 ENSMUST00000128021.1
stimulated by retinoic acid gene 6
chr10_-_13324160 0.29 ENSMUST00000105545.4
phosphatase and actin regulator 2
chr3_+_30792876 0.29 ENSMUST00000029256.7
SEC62 homolog (S. cerevisiae)
chr18_+_75018709 0.29 ENSMUST00000039608.7
dymeclin
chr17_+_29268788 0.28 ENSMUST00000064709.5
ENSMUST00000120346.1
cDNA sequence BC004004
chr16_-_48771956 0.28 ENSMUST00000170861.1
T cell receptor associated transmembrane adaptor 1
chr2_+_25403044 0.28 ENSMUST00000071442.5
neural proliferation, differentiation and control 1
chr7_-_25237849 0.28 ENSMUST00000071739.5
ENSMUST00000108411.1
glycogen synthase kinase 3 alpha
chr10_-_40142247 0.27 ENSMUST00000092566.6
solute carrier family 16 (monocarboxylic acid transporters), member 10
chr10_-_13324250 0.27 ENSMUST00000105543.1
phosphatase and actin regulator 2
chrY_-_1459771 0.26 ENSMUST00000091188.5
ubiquitin specific peptidase 9, Y chromosome
chr2_+_25403128 0.26 ENSMUST00000154809.1
ENSMUST00000055921.7
ENSMUST00000141567.1
neural proliferation, differentiation and control 1
chr11_-_21370452 0.26 ENSMUST00000102875.4
UDP-glucose pyrophosphorylase 2
chr4_-_15149755 0.25 ENSMUST00000108273.1
N-terminal EF-hand calcium binding protein 1
chrX_-_8206475 0.25 ENSMUST00000089403.3
ENSMUST00000077595.5
ENSMUST00000089402.3
ENSMUST00000082320.5
porcupine homolog (Drosophila)
chr13_+_33084113 0.24 ENSMUST00000016951.7
serine (or cysteine) peptidase inhibitor, clade B, member 1b
chr6_+_18170782 0.24 ENSMUST00000115406.1
cystic fibrosis transmembrane conductance regulator
chr13_+_23571382 0.24 ENSMUST00000079251.5
histone cluster 1, H2bg
chr10_+_4432467 0.24 ENSMUST00000095893.4
ENSMUST00000118544.1
ENSMUST00000117489.1
RIKEN cDNA 1700052N19 gene
chr3_-_146781351 0.24 ENSMUST00000005164.7
protein kinase, cAMP dependent, catalytic, beta
chr3_-_146685592 0.24 ENSMUST00000125965.1
sterile alpha motif domain containing 13
chr1_+_40429563 0.23 ENSMUST00000174335.1
interleukin 1 receptor-like 1
chr4_+_134397380 0.22 ENSMUST00000105870.1
platelet-activating factor acetylhydrolase 2
chr9_+_89199209 0.21 ENSMUST00000068569.4
B cell leukemia/lymphoma 2 related protein A1b
chr7_+_100537192 0.21 ENSMUST00000120454.1
cytochrome c oxidase assembly factor 4
chr7_-_28598140 0.21 ENSMUST00000040531.8
ENSMUST00000108283.1
sterile alpha motif domain containing 4B
p21 protein (Cdc42/Rac)-activated kinase 4
chr7_+_123123870 0.20 ENSMUST00000094053.5
trinucleotide repeat containing 6a
chr12_-_103694657 0.20 ENSMUST00000117053.1
serine (or cysteine) peptidase inhibitor, clade A, member 1F
chr9_+_72438534 0.20 ENSMUST00000034746.8
meiosis-specific nuclear structural protein 1
chr8_+_106011491 0.19 ENSMUST00000034375.4
ENSMUST00000119736.1
dihydrouridine synthase 2-like (SMM1, S. cerevisiae)
chr19_+_43689672 0.19 ENSMUST00000081079.5
ectonucleoside triphosphate diphosphohydrolase 7
chr19_+_8819401 0.19 ENSMUST00000096753.3
heterogeneous nuclear ribonucleoprotein U-like 2
chr2_-_84775420 0.18 ENSMUST00000111641.1
serine (or cysteine) peptidase inhibitor, clade G, member 1
chr14_-_46831984 0.18 ENSMUST00000181311.1
ENSMUST00000074862.2
predicted gene 10101
chr7_+_43607169 0.18 ENSMUST00000120935.1
ENSMUST00000127765.1
ENSMUST00000032661.7
zinc finger protein 819
chr6_-_130231638 0.18 ENSMUST00000088011.4
ENSMUST00000112013.1
ENSMUST00000049304.7
killer cell lectin-like receptor, subfamily A, member 7
chr9_+_18443456 0.18 ENSMUST00000051008.8
methyl-CpG binding domain protein 3-like 2
chr10_+_102159000 0.17 ENSMUST00000020039.6
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr5_-_129704259 0.17 ENSMUST00000042266.6
septin 14
chr1_-_191164815 0.16 ENSMUST00000171798.1
family with sequence similarity 71, member A
chr5_-_72559599 0.16 ENSMUST00000074948.4
ENSMUST00000087216.5
nuclear transcription factor, X-box binding-like 1
chr7_+_100537052 0.15 ENSMUST00000054310.3
cytochrome c oxidase assembly factor 4
chr16_+_20535475 0.15 ENSMUST00000090023.6
ENSMUST00000007216.8
adaptor-related protein complex 2, mu 1 subunit
chr11_-_61378306 0.15 ENSMUST00000148671.1
solute carrier family 47, member 1
chr5_-_38491948 0.15 ENSMUST00000129099.1
solute carrier family 2 (facilitated glucose transporter), member 9
chr2_-_84775388 0.14 ENSMUST00000023994.3
serine (or cysteine) peptidase inhibitor, clade G, member 1
chr6_-_145434925 0.14 ENSMUST00000111708.2
intermediate filament tail domain containing 1
chr7_+_5350542 0.14 ENSMUST00000056639.6
predicted gene 5065
chr10_-_60752773 0.13 ENSMUST00000117513.1
ENSMUST00000119595.1
solute carrier family 29 (nucleoside transporters), member 3
chr8_-_106011422 0.13 ENSMUST00000058579.5
DEAD (Asp-Glu-Ala-Asp) box polypeptide 28
chr10_+_90576708 0.13 ENSMUST00000182430.1
ENSMUST00000182960.1
ENSMUST00000182045.1
ENSMUST00000182083.1
ankyrin repeat and sterile alpha motif domain containing 1B
chr10_-_128211788 0.13 ENSMUST00000061995.8
SPRY domain containing 4
chr12_-_103694713 0.13 ENSMUST00000118101.1
serine (or cysteine) peptidase inhibitor, clade A, member 1F
chr6_-_130337502 0.12 ENSMUST00000088017.4
ENSMUST00000111998.2
killer cell lectin-like receptor, subfamily A, member 3
chr14_-_21748610 0.12 ENSMUST00000075040.2
ENSMUST00000183943.1
dual specificity phosphatase 13
chr9_+_58079310 0.12 ENSMUST00000136154.1
stimulated by retinoic acid gene 6
chr1_-_133906973 0.12 ENSMUST00000126123.1
opticin
chr15_+_66670749 0.11 ENSMUST00000065916.7
thyroglobulin
chr5_+_142629537 0.11 ENSMUST00000036872.9
ENSMUST00000110778.1
WD repeat domain, phosphoinositide interacting 2
chr2_+_110597298 0.11 ENSMUST00000045972.6
ENSMUST00000111026.2
solute carrier family 5 (sodium/glucose cotransporter), member 12
chr13_-_41847599 0.11 ENSMUST00000179758.1
androgen dependent TFPI regulating protein
chr10_-_62486575 0.10 ENSMUST00000092473.3
vacuolar protein sorting 26 homolog A (yeast)
chr5_-_69592274 0.10 ENSMUST00000174233.1
ENSMUST00000120789.1
ENSMUST00000166298.1
glucosamine-6-phosphate deaminase 2
chr9_+_99470440 0.10 ENSMUST00000056103.4
RIKEN cDNA 1600029I14 gene
chr1_+_135133272 0.09 ENSMUST00000167080.1
protein tyrosine phosphatase, non-receptor type 7
chr9_-_89092835 0.09 ENSMUST00000167113.1
tripartite motif-containing 43B
chr11_-_83302586 0.09 ENSMUST00000176374.1
peroxisomal biogenesis factor 12
chr18_+_82910863 0.09 ENSMUST00000171238.1
zinc finger protein 516
chr10_+_90576777 0.09 ENSMUST00000183136.1
ENSMUST00000182595.1
ankyrin repeat and sterile alpha motif domain containing 1B
chr11_+_69098937 0.08 ENSMUST00000021271.7
period circadian clock 1
chr17_-_78418083 0.08 ENSMUST00000070039.7
ENSMUST00000112487.1
fasciculation and elongation protein zeta 2 (zygin II)
chr11_+_101279092 0.08 ENSMUST00000103107.4
cyclin N-terminal domain containing 1
chr10_+_90576678 0.08 ENSMUST00000182284.1
ankyrin repeat and sterile alpha motif domain containing 1B
chr1_-_193035651 0.07 ENSMUST00000016344.7
synaptotagmin XIV
chr17_-_47692466 0.07 ENSMUST00000113300.1
prickle homolog 4 (Drosophila)
chr8_-_69791170 0.07 ENSMUST00000131784.1
zinc finger protein 866
chr3_+_159599177 0.07 ENSMUST00000029824.8
retinal pigment epithelium 65
chrX_+_7919816 0.06 ENSMUST00000041096.3
proprotein convertase subtilisin/kexin type 1 inhibitor
chr17_-_65772686 0.06 ENSMUST00000070673.7
RAB31, member RAS oncogene family
chr7_+_29768552 0.05 ENSMUST00000032802.4
zinc finger protein 84
chr6_-_108185552 0.05 ENSMUST00000167338.1
ENSMUST00000172188.1
ENSMUST00000032191.9
sulfatase modifying factor 1
chr8_-_95807458 0.04 ENSMUST00000098473.4
ENSMUST00000068452.8
CCR4-NOT transcription complex, subunit 1
chr10_+_100488289 0.04 ENSMUST00000164751.1
centrosomal protein 290
chr10_+_90576872 0.03 ENSMUST00000182550.1
ENSMUST00000099364.5
ankyrin repeat and sterile alpha motif domain containing 1B
chr5_-_145720124 0.03 ENSMUST00000094111.4
cytochrome P450, family 3, subfamily a, polypeptide 41A
chr13_-_41847482 0.03 ENSMUST00000072012.3
androgen dependent TFPI regulating protein
chr1_-_86111970 0.02 ENSMUST00000027431.6
5-hydroxytryptamine (serotonin) receptor 2B
chr13_+_80886095 0.02 ENSMUST00000161441.1
arrestin domain containing 3
chr19_-_8405060 0.01 ENSMUST00000064507.5
ENSMUST00000120540.1
ENSMUST00000096269.4
solute carrier family 22, member 30
chr6_-_99632376 0.01 ENSMUST00000176255.1
predicted gene 20696

Network of associatons between targets according to the STRING database.

First level regulatory network of Nkx3-1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 4.2 GO:0033869 coenzyme A catabolic process(GO:0015938) nucleoside bisphosphate catabolic process(GO:0033869) ribonucleoside bisphosphate catabolic process(GO:0034031) purine nucleoside bisphosphate catabolic process(GO:0034034) acetyl-CoA catabolic process(GO:0046356)
1.0 3.9 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.5 2.6 GO:0072383 stress granule disassembly(GO:0035617) plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386) regulation of voltage-gated sodium channel activity(GO:1905150)
0.4 2.5 GO:0002835 negative regulation of response to tumor cell(GO:0002835) negative regulation of immune response to tumor cell(GO:0002838)
0.3 1.1 GO:2000449 regulation of CD8-positive, alpha-beta T cell extravasation(GO:2000449)
0.3 0.8 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.3 1.6 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.3 0.8 GO:0060300 regulation of cytokine activity(GO:0060300)
0.3 2.3 GO:0008228 opsonization(GO:0008228)
0.2 0.7 GO:2000642 negative regulation of early endosome to late endosome transport(GO:2000642)
0.2 1.0 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.2 2.1 GO:0042427 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.2 2.9 GO:0045217 cell-cell junction maintenance(GO:0045217)
0.2 0.4 GO:0030450 regulation of complement activation, classical pathway(GO:0030450)
0.2 1.0 GO:0010579 regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.2 2.8 GO:0006968 cellular defense response(GO:0006968)
0.2 0.8 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.2 0.6 GO:0070093 negative regulation of glucagon secretion(GO:0070093)
0.2 0.7 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.2 1.3 GO:0030242 pexophagy(GO:0030242)
0.2 1.6 GO:0048208 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.1 2.2 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 0.6 GO:0002767 antigen processing and presentation of exogenous peptide antigen via MHC class Ib(GO:0002477) antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent(GO:0002481) immune response-inhibiting cell surface receptor signaling pathway(GO:0002767)
0.1 1.8 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.1 0.3 GO:0001868 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
0.1 0.3 GO:0010446 response to alkaline pH(GO:0010446)
0.1 0.7 GO:1990009 retinal cell apoptotic process(GO:1990009)
0.1 1.0 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.1 1.2 GO:0070995 NADPH oxidation(GO:0070995)
0.1 0.4 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.1 0.6 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.1 0.3 GO:0019255 UDP-glucose metabolic process(GO:0006011) glucose 1-phosphate metabolic process(GO:0019255)
0.1 0.2 GO:2000077 positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161) positive regulation of establishment of Sertoli cell barrier(GO:1904446) negative regulation of type B pancreatic cell development(GO:2000077)
0.1 1.1 GO:0070633 transepithelial transport(GO:0070633)
0.1 0.9 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.1 0.3 GO:0071879 positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.1 0.9 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.1 0.4 GO:0006561 proline biosynthetic process(GO:0006561)
0.1 0.5 GO:0071763 nuclear membrane organization(GO:0071763)
0.1 0.5 GO:0086023 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883) adrenergic receptor signaling pathway involved in heart process(GO:0086023)
0.1 0.3 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.1 0.3 GO:0006499 N-terminal protein myristoylation(GO:0006499)
0.1 0.7 GO:0060352 cell adhesion molecule production(GO:0060352)
0.1 0.4 GO:0061143 alveolar primary septum development(GO:0061143)
0.1 0.4 GO:0036337 Fas signaling pathway(GO:0036337)
0.0 0.7 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.5 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.3 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.0 0.4 GO:2000860 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.0 0.3 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.0 0.4 GO:2000018 regulation of male gonad development(GO:2000018)
0.0 0.3 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.0 0.1 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0 0.2 GO:0002826 negative regulation of T-helper 1 type immune response(GO:0002826)
0.0 0.2 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.0 0.7 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.9 GO:0070328 acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328)
0.0 0.1 GO:0061739 protein lipidation involved in autophagosome assembly(GO:0061739)
0.0 0.5 GO:0021692 cerebellar Purkinje cell layer morphogenesis(GO:0021692)
0.0 0.2 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.0 0.4 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.3 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.0 0.1 GO:0007468 regulation of rhodopsin gene expression(GO:0007468)
0.0 0.1 GO:0097167 circadian regulation of translation(GO:0097167)
0.0 0.1 GO:0015705 iodide transport(GO:0015705)
0.0 0.2 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 0.2 GO:0009191 ribonucleoside diphosphate catabolic process(GO:0009191)
0.0 0.2 GO:0040033 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.2 GO:0070986 left/right axis specification(GO:0070986)
0.0 0.8 GO:0051438 regulation of ubiquitin-protein transferase activity(GO:0051438)
0.0 0.3 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.1 GO:0015695 organic cation transport(GO:0015695)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0098843 postsynaptic endocytic zone(GO:0098843)
0.2 2.2 GO:0005579 membrane attack complex(GO:0005579)
0.2 2.8 GO:0042589 zymogen granule membrane(GO:0042589)
0.1 1.1 GO:0097342 ripoptosome(GO:0097342)
0.1 1.8 GO:0042588 zymogen granule(GO:0042588)
0.1 2.6 GO:0035253 ciliary rootlet(GO:0035253)
0.1 0.5 GO:0097447 dendritic tree(GO:0097447)
0.1 2.5 GO:0031528 microvillus membrane(GO:0031528)
0.1 0.7 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 0.5 GO:0008091 spectrin(GO:0008091)
0.1 0.8 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.1 2.3 GO:0005771 multivesicular body(GO:0005771)
0.0 0.2 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.9 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.7 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.5 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 3.6 GO:0005814 centriole(GO:0005814)
0.0 0.6 GO:0042611 MHC protein complex(GO:0042611)
0.0 2.6 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.1 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.0 5.6 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 1.1 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.2 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 0.2 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.3 GO:0005922 connexon complex(GO:0005922)
0.0 1.2 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.3 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.3 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.2 GO:0030122 AP-2 adaptor complex(GO:0030122)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 4.2 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.7 4.7 GO:0004556 alpha-amylase activity(GO:0004556)
0.6 2.5 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.5 2.1 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.4 2.6 GO:0099609 microtubule lateral binding(GO:0099609)
0.3 1.0 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798)
0.2 0.7 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.2 1.1 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.2 0.6 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.2 0.8 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.2 2.8 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.2 1.2 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 0.9 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.1 3.7 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 0.3 GO:0071633 dihydroceramidase activity(GO:0071633)
0.1 0.4 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.1 0.7 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.1 0.2 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.1 0.2 GO:0002113 interleukin-33 binding(GO:0002113)
0.1 0.8 GO:0036122 BMP binding(GO:0036122)
0.1 0.7 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 1.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.3 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.1 0.4 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.5 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.5 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.0 1.3 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.7 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 2.4 GO:0005179 hormone activity(GO:0005179)
0.0 0.6 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.3 GO:0070569 pyrimidine ribonucleotide binding(GO:0032557) uridylyltransferase activity(GO:0070569)
0.0 0.2 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0 0.5 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 1.0 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 1.1 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.2 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.4 GO:0070330 aromatase activity(GO:0070330)
0.0 0.1 GO:0070568 guanylyltransferase activity(GO:0070568)
0.0 0.1 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.0 0.2 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.4 GO:0005521 lamin binding(GO:0005521)
0.0 0.3 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 2.6 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.1 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 1.8 GO:0008083 growth factor activity(GO:0008083)
0.0 0.3 GO:0005542 folic acid binding(GO:0005542)
0.0 0.3 GO:0001848 complement binding(GO:0001848)
0.0 0.3 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0 0.5 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.4 GO:0051183 vitamin transporter activity(GO:0051183)
0.0 0.5 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.2 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.2 GO:0051400 BH domain binding(GO:0051400)
0.0 0.2 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 1.1 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.5 GO:0004364 glutathione transferase activity(GO:0004364)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.1 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 2.6 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 1.9 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.1 PID ARF 3PATHWAY Arf1 pathway
0.0 1.0 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.4 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 2.8 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.7 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 1.0 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.4 PID EPHRINB REV PATHWAY Ephrin B reverse signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.5 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.1 2.5 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 2.6 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 0.8 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.1 0.6 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 2.7 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.1 0.9 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 1.2 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 2.9 REACTOME LIPID DIGESTION MOBILIZATION AND TRANSPORT Genes involved in Lipid digestion, mobilization, and transport
0.0 1.0 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 1.2 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 1.7 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.8 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.5 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.3 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 1.0 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.0 0.7 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.3 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.3 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.2 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.5 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 3.3 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.1 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters