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12D miR HR13_24

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Results for Tbr1

Z-value: 1.03

Motif logo

Transcription factors associated with Tbr1

Gene Symbol Gene ID Gene Info
ENSMUSG00000035033.9 T-box brain transcription factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Tbr1mm10_v2_chr2_+_61804453_61804538-0.264.4e-01Click!

Activity profile of Tbr1 motif

Sorted Z-values of Tbr1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_3845050 0.92 ENSMUST00000108615.3
ENSMUST00000119469.1
paired-Ig-like receptor A2
chr11_+_83662579 0.92 ENSMUST00000019074.3
chemokine (C-C motif) ligand 4
chr7_-_46715676 0.77 ENSMUST00000006956.7
serum amyloid A 3
chr11_-_120731944 0.72 ENSMUST00000154565.1
ENSMUST00000026148.2
carbonyl reductase 2
chr7_+_44207307 0.66 ENSMUST00000077354.4
kallikrein 1-related pepidase b4
chr4_+_152186054 0.64 ENSMUST00000167926.1
acyl-CoA thioesterase 7
chr14_+_47373813 0.62 ENSMUST00000142734.1
ENSMUST00000150290.1
ENSMUST00000144794.1
ENSMUST00000146468.1
lectin, galactose binding, soluble 3
chr8_-_109579056 0.62 ENSMUST00000074898.6
haptoglobin
chr7_-_3720382 0.59 ENSMUST00000078451.6
paired Ig-like receptor B
chr2_+_144033059 0.58 ENSMUST00000037722.2
ENSMUST00000110032.1
barrier to autointegration factor 2
chr4_+_152186179 0.57 ENSMUST00000030779.3
acyl-CoA thioesterase 7
chr2_-_66124994 0.55 ENSMUST00000028378.3
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3
chr13_+_56609516 0.55 ENSMUST00000045173.8
transforming growth factor, beta induced
chr18_-_36726730 0.53 ENSMUST00000061829.6
CD14 antigen
chr7_-_3915501 0.53 ENSMUST00000038176.8
ENSMUST00000090689.4
leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
chr17_-_29237759 0.52 ENSMUST00000137727.1
ENSMUST00000024805.7
copine V
chr1_+_169969409 0.52 ENSMUST00000180638.1
RIKEN cDNA 3110045C21 gene
chrX_+_9283764 0.51 ENSMUST00000177926.1
RIKEN cDNA 1700012L04 gene
chr4_-_42773993 0.49 ENSMUST00000095114.4
chemokine (C-C motif) ligand 21A (serine)
chr5_-_108795352 0.49 ENSMUST00000004943.1
transmembrane emp24 protein transport domain containing
chr10_-_24927444 0.46 ENSMUST00000020161.8
arginase, liver
chr5_-_100572192 0.45 ENSMUST00000031264.5
placenta-specific 8
chr11_+_32283511 0.43 ENSMUST00000093209.3
hemoglobin alpha, adult chain 1
chr11_+_32296489 0.42 ENSMUST00000093207.3
hemoglobin alpha, adult chain 2
chr19_+_16435616 0.42 ENSMUST00000025602.2
guanine nucleotide binding protein, alpha 14
chr8_-_105933832 0.41 ENSMUST00000034368.6
chymotrypsin-like
chr7_+_28437447 0.41 ENSMUST00000108292.2
ENSMUST00000108289.1
glia maturation factor, gamma
chr14_+_103046977 0.41 ENSMUST00000022722.6
immunoresponsive gene 1
chr7_+_46847128 0.38 ENSMUST00000005051.4
lactate dehydrogenase A
chr3_+_94693556 0.38 ENSMUST00000090848.3
ENSMUST00000173981.1
ENSMUST00000173849.1
ENSMUST00000174223.1
selenium binding protein 2
chr4_-_134095078 0.36 ENSMUST00000000696.6
CD52 antigen
chr10_-_10558199 0.36 ENSMUST00000019974.3
RAB32, member RAS oncogene family
chr6_-_52158292 0.36 ENSMUST00000000964.5
ENSMUST00000120363.1
homeobox A1
chr1_-_174031712 0.35 ENSMUST00000059226.6
interferon activated gene 205
chr6_+_78425973 0.34 ENSMUST00000079926.5
regenerating islet-derived 1
chr11_+_108682602 0.33 ENSMUST00000106718.3
ENSMUST00000106715.1
ENSMUST00000106724.3
centrosomal protein 112
chr11_-_114934351 0.33 ENSMUST00000106581.1
ENSMUST00000074300.2
CD300 antigen like family member B
chr3_+_95526777 0.33 ENSMUST00000015667.2
ENSMUST00000116304.2
cathepsin S
chr17_+_48232755 0.32 ENSMUST00000113251.3
ENSMUST00000048782.6
triggering receptor expressed on myeloid cells 1
chr13_-_113180897 0.32 ENSMUST00000038212.7
granzyme K
chr8_+_13026024 0.31 ENSMUST00000033820.3
coagulation factor VII
chr7_-_25675047 0.31 ENSMUST00000108404.1
ENSMUST00000108405.1
ENSMUST00000079439.3
transmembrane protein 91
chr1_+_164115264 0.31 ENSMUST00000162746.1
selectin, platelet
chr6_+_138140298 0.31 ENSMUST00000008684.4
microsomal glutathione S-transferase 1
chr8_+_54600774 0.30 ENSMUST00000033917.6
spermatogenesis associated 4
chr9_-_21760275 0.30 ENSMUST00000098942.4
SPC24, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr3_-_106014630 0.29 ENSMUST00000010280.4
primary cilia formation
chrX_+_109196750 0.29 ENSMUST00000139259.1
ENSMUST00000060013.3
predicted gene 6377
chr7_+_105425817 0.29 ENSMUST00000181339.1
ENSMUST00000033189.4
cholecystokinin B receptor
chr4_-_129573637 0.29 ENSMUST00000102596.1
lymphocyte protein tyrosine kinase
chr15_-_95655960 0.29 ENSMUST00000054244.6
developing brain homeobox 2
chr2_-_62573813 0.29 ENSMUST00000174234.1
ENSMUST00000000402.9
ENSMUST00000174448.1
fibroblast activation protein
chr6_-_82774448 0.29 ENSMUST00000000642.4
hexokinase 2
chr7_-_126625676 0.28 ENSMUST00000032961.3
nuclear protein transcription regulator 1
chr2_+_164562579 0.28 ENSMUST00000017867.3
ENSMUST00000109344.2
ENSMUST00000109345.2
WAP four-disulfide core domain 2
chr7_+_128062657 0.28 ENSMUST00000120355.1
ENSMUST00000106240.2
ENSMUST00000098015.3
integrin alpha M
chr11_+_98348404 0.28 ENSMUST00000078694.6
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr3_+_145292472 0.28 ENSMUST00000029848.4
ENSMUST00000139001.1
collagen, type XXIV, alpha 1
chrX_+_100625737 0.27 ENSMUST00000048962.3
kinesin family member 4
chr3_-_30140407 0.27 ENSMUST00000108271.3
MDS1 and EVI1 complex locus
chr11_-_69900930 0.27 ENSMUST00000018714.6
ENSMUST00000128046.1
RIKEN cDNA 2810408A11 gene
chr1_-_134235420 0.27 ENSMUST00000038191.6
ENSMUST00000086465.4
adenosine A1 receptor
chr4_-_99654983 0.27 ENSMUST00000136525.1
predicted gene 12688
chr17_+_35533194 0.27 ENSMUST00000025273.8
psoriasis susceptibility 1 candidate 2 (human)
chr8_+_11713259 0.27 ENSMUST00000134409.1
RIKEN cDNA 1700128E19 gene
chr9_-_22130598 0.26 ENSMUST00000115315.2
acid phosphatase 5, tartrate resistant
chr6_-_78378851 0.26 ENSMUST00000089667.1
ENSMUST00000167492.1
regenerating islet-derived 3 delta
chrX_+_11305655 0.26 ENSMUST00000178806.1
predicted gene 14477
chr6_+_123229843 0.26 ENSMUST00000112554.2
ENSMUST00000024118.4
ENSMUST00000117130.1
C-type lectin domain family 4, member n
chrX_+_101383726 0.26 ENSMUST00000119190.1
gap junction protein, beta 1
chr6_+_42286676 0.26 ENSMUST00000031894.6
chloride channel 1
chr3_-_113356658 0.26 ENSMUST00000098667.3
amylase 2a2
chr4_-_148130678 0.26 ENSMUST00000030862.4
dorsal inhibitory axon guidance protein
chr10_+_97479470 0.25 ENSMUST00000105287.3
decorin
chr6_-_87533219 0.25 ENSMUST00000113637.2
ENSMUST00000071024.6
Rho GTPase activating protein 25
chr16_-_59553970 0.25 ENSMUST00000139989.1
beta-gamma crystallin domain containing 3
chr3_-_102782708 0.25 ENSMUST00000029450.3
ENSMUST00000172026.1
ENSMUST00000170856.1
thyroid stimulating hormone, beta subunit
chr1_-_57377476 0.25 ENSMUST00000181949.1
RIKEN cDNA 4930558J18 gene
chr5_+_128736168 0.25 ENSMUST00000086056.3
piwi-like RNA-mediated gene silencing 1
chr1_+_71652837 0.25 ENSMUST00000097699.2
apolipoprotein L 7d
chr15_-_66801577 0.25 ENSMUST00000168589.1
src-like adaptor
chr1_+_12692430 0.24 ENSMUST00000180062.1
ENSMUST00000177608.1
sulfatase 1
chr11_+_32205411 0.24 ENSMUST00000039601.3
ENSMUST00000149043.1
small nuclear ribonucleoprotein 25 (U11/U12)
chr6_-_83527452 0.24 ENSMUST00000141904.1
actin, gamma 2, smooth muscle, enteric
chrX_+_9350599 0.24 ENSMUST00000073949.2
predicted gene 14501
chr17_-_57078490 0.24 ENSMUST00000011623.7
DENN/MADD domain containing 1C
chr15_-_103310425 0.24 ENSMUST00000079824.4
G protein-coupled receptor 84
chr1_-_52500679 0.24 ENSMUST00000069792.7
Ngfi-A binding protein 1
chr2_-_164389095 0.24 ENSMUST00000167427.1
secretory leukocyte peptidase inhibitor
chr6_-_116716888 0.24 ENSMUST00000056623.6
transmembrane protein 72
chr8_-_10928449 0.24 ENSMUST00000040608.3
RIKEN cDNA 3930402G23 gene
chr13_-_70841790 0.24 ENSMUST00000080145.6
ENSMUST00000109694.2
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 16
chrX_+_96455359 0.23 ENSMUST00000033553.7
hephaestin
chr2_-_69342600 0.23 ENSMUST00000102709.1
ENSMUST00000102710.3
ENSMUST00000180142.1
ATP-binding cassette, sub-family B (MDR/TAP), member 11
chr10_+_76147451 0.23 ENSMUST00000020450.3
solute carrier family 5, member 4a
chr1_-_171059390 0.23 ENSMUST00000164044.1
ENSMUST00000169017.1
Fc receptor, IgG, low affinity III
chr1_-_191183244 0.23 ENSMUST00000027941.8
activating transcription factor 3
chr15_+_66891320 0.23 ENSMUST00000005255.2
WNT1 inducible signaling pathway protein 1
chrX_+_11318256 0.23 ENSMUST00000179859.1
predicted gene 14482
chr11_+_84957775 0.23 ENSMUST00000103194.3
carbonic anhydrase 4
chr1_-_85270543 0.23 ENSMUST00000093506.5
ENSMUST00000064341.8
RIKEN cDNA C130026I21 gene
chr9_+_5345450 0.22 ENSMUST00000151332.1
caspase 12
chr3_-_113324052 0.22 ENSMUST00000179314.1
amylase 2a3
chr9_+_22411515 0.22 ENSMUST00000058868.7
RIKEN cDNA 9530077C05 gene
chr2_+_103970115 0.22 ENSMUST00000111143.1
ENSMUST00000138815.1
LIM domain only 2
chr7_-_16259185 0.22 ENSMUST00000168818.1
complement component 5a receptor 1
chr14_+_32833955 0.22 ENSMUST00000104926.2
family with sequence similarity 170, member B
chr17_+_48264270 0.22 ENSMUST00000059873.7
ENSMUST00000154335.1
ENSMUST00000136272.1
ENSMUST00000125426.1
ENSMUST00000153420.1
triggering receptor expressed on myeloid cells-like 4
chr2_-_148046896 0.22 ENSMUST00000172928.1
ENSMUST00000047315.3
forkhead box A2
chr19_-_10203880 0.22 ENSMUST00000142241.1
ENSMUST00000116542.2
ENSMUST00000025651.5
ENSMUST00000156291.1
flap structure specific endonuclease 1
chrX_+_11299257 0.22 ENSMUST00000178729.1
predicted gene 14483
chr5_+_3571664 0.21 ENSMUST00000008451.5
RIKEN cDNA 1700109H08 gene
chr9_-_45269135 0.21 ENSMUST00000176222.1
ENSMUST00000034594.9
interleukin 10 receptor, alpha
chr1_-_170927567 0.21 ENSMUST00000046322.7
ENSMUST00000159171.1
Fc receptor-like A
chr2_+_122637844 0.21 ENSMUST00000047498.8
expressed sequence AA467197
chr6_-_83527773 0.21 ENSMUST00000152029.1
actin, gamma 2, smooth muscle, enteric
chr13_+_70882948 0.21 ENSMUST00000022091.3
RIKEN cDNA 8030423J24 gene
chrX_+_11302432 0.21 ENSMUST00000179428.1
predicted gene 14474
chr4_-_55532453 0.21 ENSMUST00000132746.1
ENSMUST00000107619.2
Kruppel-like factor 4 (gut)
chr7_+_44225430 0.20 ENSMUST00000075162.3
kallikrein 1
chr12_-_87775755 0.20 ENSMUST00000164517.2
predicted gene, 21319
chr6_+_7555053 0.20 ENSMUST00000090679.2
ENSMUST00000184986.1
tachykinin 1
chr7_-_4063195 0.20 ENSMUST00000068865.5
ENSMUST00000086400.6
leukocyte-associated Ig-like receptor 1
chr4_-_127330799 0.20 ENSMUST00000046532.3
gap junction protein, beta 3
chr3_+_96680093 0.20 ENSMUST00000130429.1
ankyrin repeat domain 35
chr5_-_137836210 0.20 ENSMUST00000110980.1
ENSMUST00000058897.4
paired immunoglobin-like type 2 receptor alpha
chr2_-_127143410 0.20 ENSMUST00000132773.1
inositol 1,4,5-triphosphate receptor interacting protein-like 1
chr7_-_127993831 0.20 ENSMUST00000033056.3
PYD and CARD domain containing
chr16_+_90738324 0.20 ENSMUST00000038197.2
melanocortin 2 receptor accessory protein
chr6_+_78405148 0.20 ENSMUST00000023906.2
regenerating islet-derived 2
chr6_+_116264186 0.20 ENSMUST00000036503.7
ENSMUST00000112900.3
zinc finger, AN1-type domain 4
chr19_+_18749983 0.19 ENSMUST00000040489.7
transient receptor potential cation channel, subfamily M, member 6
chr16_+_44811733 0.19 ENSMUST00000176819.1
ENSMUST00000176321.1
CD200 receptor 4
chrX_-_8145713 0.19 ENSMUST00000115615.2
ENSMUST00000115616.1
ENSMUST00000115621.2
RNA binding motif protein 3
chr3_-_88369730 0.19 ENSMUST00000075523.4
bone gamma-carboxyglutamate protein 3
chr14_+_68083853 0.19 ENSMUST00000022639.7
neurofilament, light polypeptide
chr15_+_54952939 0.19 ENSMUST00000181704.1
predicted gene, 26684
chr9_+_54980880 0.19 ENSMUST00000093844.3
cholinergic receptor, nicotinic, alpha polypeptide 5
chr6_+_125320633 0.19 ENSMUST00000176655.1
ENSMUST00000176110.1
sodium channel, nonvoltage-gated 1 alpha
chr17_+_57358682 0.19 ENSMUST00000086763.5
ENSMUST00000004850.7
EGF-like module containing, mucin-like, hormone receptor-like sequence 1
chr18_-_37644185 0.19 ENSMUST00000066272.4
TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr15_+_83526854 0.19 ENSMUST00000016902.3
BCL2-interacting killer
chr11_-_69666062 0.19 ENSMUST00000108654.2
ENSMUST00000018918.5
CD68 antigen
chr2_+_122637867 0.19 ENSMUST00000110512.3
expressed sequence AA467197
chr6_-_129678908 0.18 ENSMUST00000118447.1
ENSMUST00000169545.1
ENSMUST00000032270.6
ENSMUST00000032271.6
killer cell lectin-like receptor subfamily C, member 1
chr11_+_82035569 0.18 ENSMUST00000000193.5
chemokine (C-C motif) ligand 2
chr18_+_32815383 0.18 ENSMUST00000025237.3
thymic stromal lymphopoietin
chr8_-_93229517 0.18 ENSMUST00000176282.1
ENSMUST00000034173.7
carboxylesterase 1E
chr7_+_128062698 0.18 ENSMUST00000119696.1
integrin alpha M
chr11_-_69900886 0.18 ENSMUST00000108621.2
ENSMUST00000100969.2
RIKEN cDNA 2810408A11 gene
chr1_-_162813926 0.18 ENSMUST00000144916.1
ENSMUST00000140274.1
flavin containing monooxygenase 4
chr19_-_17356631 0.18 ENSMUST00000174236.1
glucosaminyl (N-acetyl) transferase 1, core 2
chr11_-_116454347 0.18 ENSMUST00000093909.4
glutamine rich 2
chr7_+_29309429 0.18 ENSMUST00000137848.1
D4, zinc and double PHD fingers family 1
chr1_-_173741717 0.18 ENSMUST00000127730.1
expressed sequence AI607873
chr12_+_84069325 0.18 ENSMUST00000046422.4
ENSMUST00000072505.4
acyl-CoA thioesterase 5
chr9_+_124121534 0.18 ENSMUST00000111442.1
ENSMUST00000171499.2
chemokine (C-C motif) receptor 5
chr3_-_30509462 0.18 ENSMUST00000173899.1
MDS1 and EVI1 complex locus
chr6_+_71293765 0.17 ENSMUST00000114185.2
predicted gene 1070
chrX_+_133908418 0.17 ENSMUST00000033606.8
ENSMUST00000113303.1
ENSMUST00000165805.1
sushi-repeat-containing protein, X-linked 2
chr7_+_30413744 0.17 ENSMUST00000032800.9
TYRO protein tyrosine kinase binding protein
chr7_-_141117772 0.17 ENSMUST00000067836.7
anoctamin 9
chr10_+_62947011 0.17 ENSMUST00000131422.1
DNA replication helicase 2 homolog (yeast)
chr7_-_126414855 0.17 ENSMUST00000032968.5
CD19 antigen
chr5_+_139423151 0.17 ENSMUST00000066211.4
G protein-coupled estrogen receptor 1
chr18_+_61275002 0.17 ENSMUST00000135688.1
phosphodiesterase 6A, cGMP-specific, rod, alpha
chr7_+_27486910 0.17 ENSMUST00000008528.7
SERTA domain containing 1
chr1_-_172590463 0.17 ENSMUST00000065679.6
SLAM family member 8
chr6_-_36811361 0.17 ENSMUST00000101534.1
pleiotrophin
chr10_+_80494835 0.17 ENSMUST00000051773.8
one cut domain, family member 3
chr5_+_110330697 0.17 ENSMUST00000112481.1
polymerase (DNA directed), epsilon
chr15_+_80623499 0.17 ENSMUST00000043149.7
GRB2-related adaptor protein 2
chrX_+_159840463 0.17 ENSMUST00000112451.1
ENSMUST00000112453.2
SH3-domain kinase binding protein 1
chr2_-_129699833 0.17 ENSMUST00000028883.5
prodynorphin
chr8_+_113643206 0.16 ENSMUST00000034219.4
ENSMUST00000095173.1
synaptonemal complex central element protein 1 like
chr3_+_94933041 0.16 ENSMUST00000090839.5
selenium binding protein 1
chr4_+_148130883 0.16 ENSMUST00000084129.2
MAD2 mitotic arrest deficient-like 2
chr10_+_7832457 0.16 ENSMUST00000039484.4
zinc finger CCCH type containing 12D
chr7_-_127930066 0.16 ENSMUST00000032988.8
protease, serine, 8 (prostasin)
chr3_+_135212557 0.16 ENSMUST00000062893.7
centromere protein E
chr9_+_111004811 0.16 ENSMUST00000080872.4
predicted gene 10030
chr11_-_84068766 0.16 ENSMUST00000018792.5
dual specificity phosphatase 14
chr7_-_100658394 0.16 ENSMUST00000138830.1
ENSMUST00000107044.3
ENSMUST00000116287.2
pleckstrin homology domain containing, family B (evectins) member 1
chr6_+_124304646 0.16 ENSMUST00000112541.2
ENSMUST00000032234.2
CD163 antigen
chr15_+_83563571 0.16 ENSMUST00000047419.6
translocator protein
chr11_-_78984831 0.16 ENSMUST00000073001.4
ENSMUST00000108269.3
lectin, galactose binding, soluble 9
chr8_-_80057989 0.16 ENSMUST00000079038.2
Hedgehog-interacting protein
chr10_+_80879720 0.16 ENSMUST00000105333.2
transmembrane protease, serine 9
chr16_-_48771956 0.16 ENSMUST00000170861.1
T cell receptor associated transmembrane adaptor 1
chr17_+_46681038 0.16 ENSMUST00000002845.6
male enhanced antigen 1
chr11_+_32205483 0.15 ENSMUST00000121182.1
small nuclear ribonucleoprotein 25 (U11/U12)
chr4_+_42950369 0.15 ENSMUST00000084662.5
DnaJ (Hsp40) homolog, subfamily B, member 5
chr3_-_145649970 0.15 ENSMUST00000029846.3
cysteine rich protein 61
chr3_+_96629919 0.15 ENSMUST00000048915.6
RNA binding motif protein 8a
chr12_+_105603085 0.15 ENSMUST00000182899.1
ENSMUST00000183086.1
bradykinin receptor, beta 1
chr6_+_42286709 0.15 ENSMUST00000163936.1
chloride channel 1
chr14_+_31641051 0.15 ENSMUST00000090147.6
biotinidase
chr1_+_131970589 0.15 ENSMUST00000027695.6
solute carrier family 45, member 3
chr11_-_94392917 0.15 ENSMUST00000178136.1
ENSMUST00000021231.7
ATP-binding cassette, sub-family C (CFTR/MRP), member 3
chr1_-_173741795 0.15 ENSMUST00000042610.7
expressed sequence AI607873

Network of associatons between targets according to the STRING database.

First level regulatory network of Tbr1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.2 GO:1900535 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.2 0.9 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.2 0.6 GO:2000521 positive regulation of mononuclear cell migration(GO:0071677) negative regulation of immunological synapse formation(GO:2000521) regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001188) negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001189)
0.2 0.6 GO:2000295 regulation of hydrogen peroxide catabolic process(GO:2000295)
0.2 0.5 GO:0071725 response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.2 0.5 GO:2000547 regulation of dendritic cell dendrite assembly(GO:2000547)
0.1 0.4 GO:0071846 actin filament debranching(GO:0071846)
0.1 0.7 GO:0006116 NADH oxidation(GO:0006116)
0.1 0.4 GO:0021570 rhombomere 4 development(GO:0021570)
0.1 0.5 GO:0043091 L-arginine import(GO:0043091) arginine import(GO:0090467)
0.1 0.3 GO:0034769 basement membrane disassembly(GO:0034769)
0.1 0.3 GO:0090265 immune complex clearance by monocytes and macrophages(GO:0002436) regulation of immune complex clearance by monocytes and macrophages(GO:0090264) positive regulation of immune complex clearance by monocytes and macrophages(GO:0090265)
0.1 0.3 GO:0010716 regulation of collagen catabolic process(GO:0010710) negative regulation of extracellular matrix disassembly(GO:0010716)
0.1 0.6 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.1 0.3 GO:0070256 positive regulation of nucleobase-containing compound transport(GO:0032241) regulation of nucleoside transport(GO:0032242) negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) negative regulation of mucus secretion(GO:0070256)
0.1 0.3 GO:0045014 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.1 0.5 GO:0014004 microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.1 0.3 GO:0010641 positive regulation of platelet-derived growth factor receptor signaling pathway(GO:0010641)
0.1 0.2 GO:0001788 antibody-dependent cellular cytotoxicity(GO:0001788)
0.1 0.2 GO:1903984 positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.1 0.3 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.1 0.4 GO:0019244 lactate biosynthetic process from pyruvate(GO:0019244)
0.1 0.1 GO:0072679 thymocyte migration(GO:0072679)
0.1 0.3 GO:0090274 positive regulation of somatostatin secretion(GO:0090274)
0.1 0.3 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.1 0.4 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.1 0.3 GO:2000562 negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.1 0.2 GO:0045415 negative regulation of interleukin-8 biosynthetic process(GO:0045415)
0.1 0.2 GO:2000852 corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852)
0.1 0.2 GO:0002588 myeloid dendritic cell activation involved in immune response(GO:0002277) positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002582) positive regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002588)
0.1 0.2 GO:0019343 cysteine biosynthetic process via cystathionine(GO:0019343)
0.1 0.3 GO:1903232 melanosome assembly(GO:1903232)
0.1 0.4 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.1 0.3 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.1 0.2 GO:0033693 neurofilament bundle assembly(GO:0033693)
0.1 0.2 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.1 1.2 GO:0080184 response to stilbenoid(GO:0035634) response to phenylpropanoid(GO:0080184)
0.1 0.4 GO:0070945 neutrophil mediated killing of gram-negative bacterium(GO:0070945)
0.1 0.2 GO:2001226 negative regulation of chloride transport(GO:2001226)
0.1 0.3 GO:1901526 negative regulation of mitochondrial membrane permeability(GO:0035795) positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.1 0.2 GO:0010578 regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579) positive regulation of inositol trisphosphate biosynthetic process(GO:0032962) response to mineralocorticoid(GO:0051385) regulation of cardiac vascular smooth muscle cell differentiation(GO:2000722) positive regulation of cardiac vascular smooth muscle cell differentiation(GO:2000724)
0.1 0.2 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.1 0.3 GO:0052151 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139)
0.1 0.2 GO:0045004 DNA replication proofreading(GO:0045004)
0.1 0.4 GO:0015722 canalicular bile acid transport(GO:0015722)
0.1 0.4 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1 0.2 GO:0015770 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.0 0.1 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 0.1 GO:2000016 negative regulation of determination of dorsal identity(GO:2000016)
0.0 0.2 GO:0030421 defecation(GO:0030421)
0.0 0.2 GO:0032789 saturated monocarboxylic acid metabolic process(GO:0032788) unsaturated monocarboxylic acid metabolic process(GO:0032789)
0.0 0.3 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.0 0.1 GO:0046271 phenylpropanoid catabolic process(GO:0046271)
0.0 0.2 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.2 GO:0080154 regulation of fertilization(GO:0080154)
0.0 0.1 GO:0002355 detection of tumor cell(GO:0002355)
0.0 0.1 GO:1903002 negative regulation of presynaptic membrane organization(GO:1901630) regulation of lipid transport across blood brain barrier(GO:1903000) positive regulation of lipid transport across blood brain barrier(GO:1903002)
0.0 0.2 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.0 0.2 GO:0010940 positive regulation of necrotic cell death(GO:0010940)
0.0 0.1 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.0 0.5 GO:0007128 meiotic prophase I(GO:0007128) prophase(GO:0051324)
0.0 0.1 GO:0045645 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.0 0.1 GO:0061090 positive regulation of sequestering of zinc ion(GO:0061090)
0.0 0.5 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.1 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.0 0.1 GO:0043397 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397) positive regulation of corticotropin-releasing hormone secretion(GO:0051466) regulation of G-protein coupled receptor internalization(GO:1904020)
0.0 0.1 GO:0002270 plasmacytoid dendritic cell activation(GO:0002270)
0.0 0.1 GO:0006015 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0 0.2 GO:2001204 regulation of osteoclast development(GO:2001204)
0.0 0.1 GO:0010536 positive regulation of activation of Janus kinase activity(GO:0010536)
0.0 0.1 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.0 0.1 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.0 0.2 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.0 0.2 GO:0042737 drug catabolic process(GO:0042737)
0.0 0.1 GO:0021882 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882)
0.0 0.1 GO:0045041 protein import into mitochondrial intermembrane space(GO:0045041)
0.0 0.6 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.0 0.1 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.3 GO:0070474 positive regulation of uterine smooth muscle contraction(GO:0070474)
0.0 0.1 GO:0035262 gonad morphogenesis(GO:0035262)
0.0 0.1 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.0 0.1 GO:0006216 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.0 0.1 GO:0023041 neuronal signal transduction(GO:0023041)
0.0 0.3 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.0 0.1 GO:0030862 neuroblast division in subventricular zone(GO:0021849) positive regulation of polarized epithelial cell differentiation(GO:0030862)
0.0 0.1 GO:0032218 riboflavin transport(GO:0032218)
0.0 0.4 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.0 0.1 GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.0 0.3 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.0 0.4 GO:0097264 self proteolysis(GO:0097264)
0.0 0.7 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.0 0.1 GO:0019364 pyridine nucleotide catabolic process(GO:0019364)
0.0 0.2 GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987)
0.0 0.1 GO:0002538 arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
0.0 0.2 GO:2000304 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.0 0.3 GO:1904659 glucose transmembrane transport(GO:1904659)
0.0 0.1 GO:0002767 immune response-inhibiting cell surface receptor signaling pathway(GO:0002767)
0.0 0.1 GO:2000609 regulation of thyroid hormone generation(GO:2000609)
0.0 0.1 GO:1902953 positive regulation of ER to Golgi vesicle-mediated transport(GO:1902953)
0.0 0.0 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.0 0.1 GO:0032485 regulation of Ral protein signal transduction(GO:0032485)
0.0 0.1 GO:0002353 kinin cascade(GO:0002254) plasma kallikrein-kinin cascade(GO:0002353)
0.0 0.1 GO:0033058 directional locomotion(GO:0033058)
0.0 0.1 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.1 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.0 0.3 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.1 GO:0060722 spongiotrophoblast cell proliferation(GO:0060720) cell proliferation involved in embryonic placenta development(GO:0060722)
0.0 0.1 GO:0030091 protein repair(GO:0030091)
0.0 0.1 GO:0072675 osteoclast fusion(GO:0072675)
0.0 0.1 GO:0051866 general adaptation syndrome(GO:0051866)
0.0 0.2 GO:0015670 carbon dioxide transport(GO:0015670)
0.0 0.1 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.0 0.1 GO:0090315 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933) negative regulation of protein targeting to membrane(GO:0090315)
0.0 0.1 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.0 0.1 GO:2000383 regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
0.0 0.1 GO:0072531 pyrimidine-containing compound transmembrane transport(GO:0072531)
0.0 0.1 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.0 0.1 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.0 0.4 GO:0002446 neutrophil mediated immunity(GO:0002446)
0.0 0.1 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.0 0.1 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.2 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.1 GO:0055130 D-serine catabolic process(GO:0036088) D-alanine family amino acid metabolic process(GO:0046144) D-alanine metabolic process(GO:0046436) D-alanine catabolic process(GO:0055130)
0.0 0.1 GO:0006068 ethanol catabolic process(GO:0006068)
0.0 0.1 GO:0006481 C-terminal protein methylation(GO:0006481)
0.0 0.1 GO:0032672 interleukin-3 production(GO:0032632) regulation of interleukin-3 production(GO:0032672) positive regulation of interleukin-3 production(GO:0032752) interleukin-3 biosynthetic process(GO:0042223) granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0042253) regulation of interleukin-3 biosynthetic process(GO:0045399) positive regulation of interleukin-3 biosynthetic process(GO:0045401) regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045423) positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425)
0.0 0.1 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.0 0.1 GO:0003257 positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation(GO:0003257)
0.0 0.1 GO:0065001 proximal/distal axis specification(GO:0009946) specification of axis polarity(GO:0065001)
0.0 0.1 GO:0010286 heat acclimation(GO:0010286)
0.0 0.0 GO:0060696 regulation of phospholipid catabolic process(GO:0060696)
0.0 0.1 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.0 0.5 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.0 0.6 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.1 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.0 0.1 GO:1900020 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.0 0.2 GO:0015868 purine ribonucleotide transport(GO:0015868)
0.0 0.2 GO:0035095 behavioral response to nicotine(GO:0035095)
0.0 0.1 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.3 GO:2000194 regulation of female gonad development(GO:2000194)
0.0 0.7 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.2 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.0 0.2 GO:0060352 cell adhesion molecule production(GO:0060352)
0.0 0.1 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.1 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
0.0 0.1 GO:0090009 primitive streak formation(GO:0090009)
0.0 0.1 GO:2000402 negative regulation of lymphocyte migration(GO:2000402)
0.0 0.1 GO:1903998 regulation of eating behavior(GO:1903998)
0.0 0.1 GO:0070814 hydrogen sulfide biosynthetic process(GO:0070814)
0.0 0.1 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700)
0.0 0.2 GO:0006751 glutathione catabolic process(GO:0006751)
0.0 0.1 GO:0015074 DNA integration(GO:0015074)
0.0 0.2 GO:0002517 T cell tolerance induction(GO:0002517)
0.0 0.0 GO:1903059 negative regulation of lipoprotein metabolic process(GO:0050748) regulation of protein lipidation(GO:1903059)
0.0 0.0 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.0 0.2 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.0 0.0 GO:0045226 hyaluranon cable assembly(GO:0036118) extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.0 0.0 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.0 0.1 GO:0009181 purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
0.0 0.1 GO:1990928 response to amino acid starvation(GO:1990928)
0.0 0.1 GO:0015879 carnitine transport(GO:0015879)
0.0 0.0 GO:0002838 negative regulation of response to tumor cell(GO:0002835) negative regulation of immune response to tumor cell(GO:0002838) negative regulation of natural killer cell mediated immune response to tumor cell(GO:0002856) negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002859)
0.0 0.0 GO:2000642 negative regulation of early endosome to late endosome transport(GO:2000642)
0.0 0.3 GO:0061051 positive regulation of cell growth involved in cardiac muscle cell development(GO:0061051)
0.0 0.1 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
0.0 0.1 GO:1904715 negative regulation of chaperone-mediated autophagy(GO:1904715)
0.0 0.1 GO:0036093 germ cell proliferation(GO:0036093)
0.0 0.0 GO:0071043 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043) polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.0 0.1 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.0 0.3 GO:0021516 dorsal spinal cord development(GO:0021516)
0.0 0.1 GO:0046037 GMP metabolic process(GO:0046037)
0.0 0.2 GO:0019731 antibacterial humoral response(GO:0019731)
0.0 0.1 GO:0034379 very-low-density lipoprotein particle assembly(GO:0034379)
0.0 0.1 GO:2001032 cell quiescence(GO:0044838) regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.0 0.2 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.1 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.1 GO:1901837 negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837)
0.0 0.0 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.0 0.1 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.0 GO:0003218 cardiac left ventricle formation(GO:0003218)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.5 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.1 0.6 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 0.3 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 0.2 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.1 0.2 GO:0044299 C-fiber(GO:0044299)
0.1 0.3 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.1 0.3 GO:0031262 Ndc80 complex(GO:0031262)
0.0 0.2 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.0 0.2 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 0.5 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.3 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.9 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.2 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.3 GO:0042575 DNA polymerase complex(GO:0042575)
0.0 0.4 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.3 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.5 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.3 GO:0097433 dense body(GO:0097433)
0.0 0.1 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.0 0.2 GO:0070652 HAUS complex(GO:0070652)
0.0 0.1 GO:0071001 U4/U6 snRNP(GO:0071001)
0.0 0.6 GO:0097386 glial cell projection(GO:0097386)
0.0 0.2 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.0 0.1 GO:1990590 ATF1-ATF4 transcription factor complex(GO:1990590)
0.0 0.1 GO:0035976 AP1 complex(GO:0035976)
0.0 0.5 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.1 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.0 0.1 GO:0005584 collagen type I trimer(GO:0005584)
0.0 0.2 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.1 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 0.2 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0 0.1 GO:0000125 PCAF complex(GO:0000125)
0.0 0.2 GO:0044327 dendritic spine membrane(GO:0032591) dendritic spine head(GO:0044327)
0.0 0.4 GO:0005922 connexon complex(GO:0005922)
0.0 0.6 GO:0008305 integrin complex(GO:0008305)
0.0 0.4 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.1 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.1 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.1 GO:0070847 core mediator complex(GO:0070847)
0.0 0.1 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.0 0.1 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 0.1 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.2 GO:0032279 asymmetric synapse(GO:0032279)
0.0 0.0 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.0 0.3 GO:0042588 zymogen granule(GO:0042588)
0.0 0.2 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.0 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 0.3 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.0 GO:0005713 recombination nodule(GO:0005713)
0.0 0.3 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.7 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.0 GO:0044218 other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.0 0.3 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.0 GO:0032783 ELL-EAF complex(GO:0032783)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.2 0.8 GO:0031720 haptoglobin binding(GO:0031720)
0.2 0.6 GO:0048030 disaccharide binding(GO:0048030)
0.2 0.6 GO:0030492 hemoglobin binding(GO:0030492)
0.2 0.7 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.1 0.3 GO:0035650 AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651)
0.1 0.8 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.1 0.4 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.1 0.3 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
0.1 0.3 GO:0031750 D3 dopamine receptor binding(GO:0031750) D5 dopamine receptor binding(GO:0031752)
0.1 0.5 GO:0071723 lipopeptide binding(GO:0071723)
0.1 1.6 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.1 0.4 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.1 0.3 GO:0042806 fucose binding(GO:0042806)
0.1 0.5 GO:0004556 alpha-amylase activity(GO:0004556)
0.1 0.5 GO:0001851 complement component C3b binding(GO:0001851)
0.1 0.3 GO:0034584 piRNA binding(GO:0034584)
0.1 0.2 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.1 0.3 GO:0042610 CD8 receptor binding(GO:0042610)
0.1 0.2 GO:0017082 mineralocorticoid receptor activity(GO:0017082)
0.1 0.3 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.1 0.2 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.1 0.5 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.1 0.2 GO:0004947 bradykinin receptor activity(GO:0004947)
0.1 0.2 GO:0015157 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.0 0.1 GO:0098809 nitrite reductase activity(GO:0098809)
0.0 0.2 GO:0004966 galanin receptor activity(GO:0004966)
0.0 0.2 GO:0008147 structural constituent of bone(GO:0008147)
0.0 0.2 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.0 0.1 GO:0035717 chemokine (C-C motif) ligand 7 binding(GO:0035717)
0.0 0.2 GO:0019770 IgG receptor activity(GO:0019770)
0.0 0.3 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.2 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.0 0.5 GO:0008430 selenium binding(GO:0008430)
0.0 0.1 GO:0046911 metal chelating activity(GO:0046911)
0.0 0.6 GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.0 0.3 GO:0016936 galactoside binding(GO:0016936)
0.0 0.2 GO:0097108 hedgehog family protein binding(GO:0097108)
0.0 0.1 GO:0000402 open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402)
0.0 0.1 GO:0001847 opsonin receptor activity(GO:0001847)
0.0 0.3 GO:0019158 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.1 GO:0019767 IgE receptor activity(GO:0019767)
0.0 0.1 GO:0004051 arachidonate 5-lipoxygenase activity(GO:0004051)
0.0 0.1 GO:0005502 11-cis retinal binding(GO:0005502)
0.0 0.3 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.0 0.5 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.3 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.1 GO:0030629 U6 snRNA 3'-end binding(GO:0030629)
0.0 0.2 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.7 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.1 GO:0098918 structural constituent of synapse(GO:0098918) structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.0 0.1 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.0 0.3 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.4 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.2 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.1 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.0 0.0 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0 0.1 GO:0032217 riboflavin transporter activity(GO:0032217)
0.0 0.3 GO:0008297 single-stranded DNA exodeoxyribonuclease activity(GO:0008297)
0.0 0.1 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.0 0.3 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.2 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.1 GO:0005124 scavenger receptor binding(GO:0005124)
0.0 0.2 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.2 GO:0004920 interleukin-10 receptor activity(GO:0004920)
0.0 0.2 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.1 GO:0004854 xanthine dehydrogenase activity(GO:0004854) oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor(GO:0016726)
0.0 0.2 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.1 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.0 0.3 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.0 1.3 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.4 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.1 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.0 0.1 GO:0045159 myosin II binding(GO:0045159)
0.0 0.4 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.5 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.5 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.1 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.1 GO:0003880 protein C-terminal carboxyl O-methyltransferase activity(GO:0003880)
0.0 0.2 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.1 GO:0047936 glucose 1-dehydrogenase [NAD(P)] activity(GO:0047936)
0.0 0.1 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.1 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.0 0.2 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.2 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.1 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.2 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 0.4 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.1 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 0.1 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 0.1 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.2 GO:0042166 acetylcholine binding(GO:0042166)
0.0 0.2 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.0 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.1 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.0 0.1 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.1 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.1 GO:1990446 U1 snRNP binding(GO:1990446)
0.0 0.1 GO:0003884 D-amino-acid oxidase activity(GO:0003884)
0.0 0.1 GO:0046923 ER retention sequence binding(GO:0046923)
0.0 0.3 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.0 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.0 0.1 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 0.1 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.1 GO:0042284 sphingolipid delta-4 desaturase activity(GO:0042284)
0.0 0.1 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.1 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.1 GO:0098821 BMP receptor activity(GO:0098821)
0.0 0.0 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.0 0.6 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.0 GO:0032137 guanine/thymine mispair binding(GO:0032137)
0.0 0.1 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.0 0.0 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.0 0.0 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
0.0 0.1 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 0.1 GO:0008527 taste receptor activity(GO:0008527)
0.0 0.0 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.0 0.0 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.0 0.1 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.1 GO:0097642 calcitonin family receptor activity(GO:0097642)
0.0 0.1 GO:0030547 receptor inhibitor activity(GO:0030547)
0.0 0.0 GO:0050501 hyaluronan synthase activity(GO:0050501)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.4 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.7 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 1.5 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 1.0 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.1 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 0.7 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.2 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.9 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.1 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 0.6 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.3 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 0.3 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.1 0.4 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.7 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.3 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.6 REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX Genes involved in TRAF6 mediated induction of TAK1 complex
0.0 0.2 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.4 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.4 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.3 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 1.1 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.1 REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND Genes involved in Processive synthesis on the lagging strand
0.0 0.2 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.0 0.3 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.1 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.2 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.4 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 0.3 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.8 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.2 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.4 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 0.3 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.8 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.3 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.3 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 0.2 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.4 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.4 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 1.0 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.0 0.1 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation