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12D miR HR13_24

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Results for Nkx2-3

Z-value: 1.23

Motif logo

Transcription factors associated with Nkx2-3

Gene Symbol Gene ID Gene Info
ENSMUSG00000044220.12 NK2 homeobox 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nkx2-3mm10_v2_chr19_+_43612299_436123250.867.4e-04Click!

Activity profile of Nkx2-3 motif

Sorted Z-values of Nkx2-3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_33086366 3.81 ENSMUST00000049618.2
GTPase activating RANGAP domain-like 3
chr15_-_79285502 3.49 ENSMUST00000165408.1
BAI1-associated protein 2-like 2
chr15_-_79285470 3.41 ENSMUST00000170955.1
BAI1-associated protein 2-like 2
chr16_-_63864114 2.52 ENSMUST00000064405.6
Eph receptor A3
chr16_+_7069825 2.51 ENSMUST00000056416.7
RNA binding protein, fox-1 homolog (C. elegans) 1
chr11_-_119547744 2.17 ENSMUST00000026670.4
neuronal pentraxin 1
chr16_-_44333135 2.03 ENSMUST00000047446.6
SID1 transmembrane family, member 1
chr16_-_44332925 1.97 ENSMUST00000136381.1
SID1 transmembrane family, member 1
chr5_-_72587544 1.95 ENSMUST00000031124.4
predicted gene 5868
chr18_+_4993795 1.94 ENSMUST00000153016.1
supervillin
chr2_-_166155272 1.77 ENSMUST00000088086.3
sulfatase 2
chr11_+_116671658 1.69 ENSMUST00000106378.1
ENSMUST00000144049.1
RIKEN cDNA 1810032O08 gene
chr2_-_166155624 1.67 ENSMUST00000109249.2
sulfatase 2
chr9_+_32116040 1.62 ENSMUST00000174641.1
Rho GTPase activating protein 32
chr3_-_36571952 1.48 ENSMUST00000029270.3
cyclin A2
chr6_+_21986887 1.48 ENSMUST00000151315.1
cadherin-like and PC-esterase domain containing 1
chr8_-_62123106 1.42 ENSMUST00000034052.6
ENSMUST00000034054.7
annexin A10
chr6_+_63255971 1.41 ENSMUST00000159561.1
ENSMUST00000095852.3
glutamate receptor, ionotropic, delta 2
chr2_+_152847993 1.36 ENSMUST00000028969.8
TPX2, microtubule-associated protein homolog (Xenopus laevis)
chr12_+_38783455 1.34 ENSMUST00000161980.1
ENSMUST00000160701.1
ets variant gene 1
chr8_-_31918203 1.33 ENSMUST00000073884.4
neuregulin 1
chr13_+_55399648 1.31 ENSMUST00000057167.7
solute carrier family 34 (sodium phosphate), member 1
chr12_+_38783503 1.29 ENSMUST00000159334.1
ets variant gene 1
chr6_-_148946146 1.28 ENSMUST00000132696.1
family with sequence similarity 60, member A
chr3_-_26133734 1.26 ENSMUST00000108308.3
ENSMUST00000075054.4
neuroligin 1
chr3_-_88410295 1.24 ENSMUST00000056370.7
polyamine-modulated factor 1
chr12_+_38780284 1.22 ENSMUST00000162563.1
ENSMUST00000161164.1
ENSMUST00000160996.1
ets variant gene 1
chr12_+_117843489 1.11 ENSMUST00000021592.9
cell division cycle associated 7 like
chr19_-_53371766 1.11 ENSMUST00000086887.1
predicted gene 10197
chr1_+_40515362 1.09 ENSMUST00000027237.5
interleukin 18 receptor accessory protein
chr1_+_66321708 1.08 ENSMUST00000114013.1
microtubule-associated protein 2
chr11_-_98053415 1.06 ENSMUST00000017544.2
SH3 and cysteine rich domain 2
chr2_+_170511418 1.04 ENSMUST00000136839.1
ENSMUST00000109148.1
ENSMUST00000170167.1
prefoldin 4
chr18_+_4920509 1.04 ENSMUST00000126977.1
supervillin
chr3_+_64081642 1.03 ENSMUST00000029406.4
vomeronasal 2, receptor 1
chr3_-_49757257 1.02 ENSMUST00000035931.7
protocadherin 18
chr3_+_84952146 1.01 ENSMUST00000029727.7
F-box and WD-40 domain protein 7
chr9_-_16378231 1.01 ENSMUST00000082170.5
FAT tumor suppressor homolog 3 (Drosophila)
chr3_-_87174657 1.00 ENSMUST00000159976.1
ENSMUST00000107618.2
kin of IRRE like (Drosophila)
chr12_+_38780817 0.99 ENSMUST00000160856.1
ets variant gene 1
chrX_+_150547375 0.97 ENSMUST00000066337.6
ENSMUST00000112715.1
aminolevulinic acid synthase 2, erythroid
chr2_+_181767040 0.95 ENSMUST00000108756.1
myelin transcription factor 1
chr15_+_92597104 0.91 ENSMUST00000035399.8
PDZ domain containing RING finger 4
chr8_-_22694061 0.91 ENSMUST00000131767.1
inhibitor of kappaB kinase beta
chr2_+_136057927 0.91 ENSMUST00000057503.6
lysosomal-associated membrane protein family, member 5
chr2_+_181767283 0.90 ENSMUST00000108757.2
myelin transcription factor 1
chrX_-_162964557 0.90 ENSMUST00000038769.2
S100 calcium binding protein G
chr16_-_5013505 0.87 ENSMUST00000023191.10
ENSMUST00000090453.5
rogdi homolog (Drosophila)
chr13_+_49544443 0.87 ENSMUST00000177948.1
ENSMUST00000021820.6
asporin
chr1_-_183147461 0.87 ENSMUST00000171366.1
dispatched homolog 1 (Drosophila)
chr19_-_15924560 0.87 ENSMUST00000162053.1
phosphoserine aminotransferase 1
chr19_-_44552831 0.86 ENSMUST00000166808.1
predicted gene 20538
chr6_+_15196949 0.86 ENSMUST00000151301.1
ENSMUST00000131414.1
ENSMUST00000140557.1
ENSMUST00000115469.1
forkhead box P2
chrX_-_74246534 0.85 ENSMUST00000101454.2
ENSMUST00000033699.6
filamin, alpha
chr4_-_91376433 0.83 ENSMUST00000107109.2
ENSMUST00000107111.2
ENSMUST00000107120.1
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr3_+_137624031 0.83 ENSMUST00000165845.1
DNA-damage-inducible transcript 4-like
chr13_-_28953690 0.82 ENSMUST00000067230.5
SRY-box containing gene 4
chrX_-_48208870 0.82 ENSMUST00000088935.3
zinc finger, DHHC domain containing 9
chr3_+_68572245 0.81 ENSMUST00000170788.2
schwannomin interacting protein 1
chr6_+_145934113 0.81 ENSMUST00000032383.7
sarcospan
chr4_+_127172866 0.81 ENSMUST00000106094.2
discs, large (Drosophila) homolog-associated protein 3
chr2_-_64975762 0.79 ENSMUST00000156765.1
growth factor receptor bound protein 14
chr15_+_102073773 0.79 ENSMUST00000169681.1
eukaryotic translation initiation factor 4B
chr15_-_98934522 0.79 ENSMUST00000077577.7
tubulin, alpha 1B
chr1_+_6734827 0.78 ENSMUST00000139838.1
suppression of tumorigenicity 18
chr4_+_140700487 0.78 ENSMUST00000071169.2
regulator of chromosome condensation 2
chr9_+_72806874 0.77 ENSMUST00000055535.8
protogenin homolog (Gallus gallus)
chr7_-_38019505 0.77 ENSMUST00000085513.4
URI1, prefoldin-like chaperone
chr3_+_102010138 0.77 ENSMUST00000066187.4
nescient helix loop helix 2
chr13_-_76056996 0.76 ENSMUST00000056130.4
G protein-coupled receptor 150
chr15_-_43869993 0.75 ENSMUST00000067469.4
transmembrane protein 74
chr13_+_83504032 0.75 ENSMUST00000163888.1
ENSMUST00000005722.7
myocyte enhancer factor 2C
chr11_+_120232921 0.73 ENSMUST00000122148.1
ENSMUST00000044985.7
BAH domain and coiled-coil containing 1
chrX_+_73675500 0.73 ENSMUST00000171398.1
solute carrier family 6 (neurotransmitter transporter, creatine), member 8
chr4_+_85205120 0.72 ENSMUST00000107188.3
SH3-domain GRB2-like 2
chr16_-_95586585 0.71 ENSMUST00000077773.6
avian erythroblastosis virus E-26 (v-ets) oncogene related
chr19_+_8740712 0.69 ENSMUST00000163172.1
RIKEN cDNA 1700092M07 gene
chr2_-_174346712 0.69 ENSMUST00000168292.1
predicted gene, 20721
chr18_+_69593361 0.68 ENSMUST00000114978.2
ENSMUST00000114977.1
transcription factor 4
chr4_-_91376490 0.68 ENSMUST00000107124.3
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr3_+_68869563 0.67 ENSMUST00000054551.2
RIKEN cDNA 1110032F04 gene
chr15_+_55307743 0.67 ENSMUST00000023053.5
ENSMUST00000110221.2
ENSMUST00000110217.3
collagen, type XIV, alpha 1
chrX_-_157415286 0.65 ENSMUST00000079945.4
ENSMUST00000138396.1
phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets)
chr15_+_28203726 0.64 ENSMUST00000067048.6
dynein, axonemal, heavy chain 5
chr13_-_78196373 0.64 ENSMUST00000125176.2
nuclear receptor subfamily 2, group F, member 1
chr2_-_65529275 0.62 ENSMUST00000126837.1
sodium channel, voltage-gated, type III, alpha
chr19_-_55241236 0.62 ENSMUST00000069183.6
guanylate cyclase 2g
chr7_-_116198487 0.62 ENSMUST00000181981.1
pleckstrin homology domain containing, family A member 7
chr13_-_36734450 0.62 ENSMUST00000037623.8
neuritin 1
chr1_+_187997821 0.61 ENSMUST00000027906.6
estrogen-related receptor gamma
chr17_-_48432723 0.61 ENSMUST00000046549.3
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 2
chr1_+_187997835 0.61 ENSMUST00000110938.1
estrogen-related receptor gamma
chr8_-_48555846 0.59 ENSMUST00000110345.1
ENSMUST00000110343.1
teneurin transmembrane protein 3
chrX_-_16911774 0.56 ENSMUST00000040134.7
Norrie disease (pseudoglioma) (human)
chr18_-_75697639 0.56 ENSMUST00000165559.1
CBP80/20-dependent translation initiation factor
chrX_-_48208566 0.56 ENSMUST00000037960.4
zinc finger, DHHC domain containing 9
chrX_+_93654863 0.55 ENSMUST00000113933.2
phosphate cytidylyltransferase 1, choline, beta isoform
chr4_+_136143497 0.55 ENSMUST00000008016.2
inhibitor of DNA binding 3
chr14_+_57524734 0.54 ENSMUST00000089494.4
interleukin 17D
chr12_+_38781093 0.54 ENSMUST00000161513.1
ets variant gene 1
chr9_-_53248106 0.54 ENSMUST00000065630.6
DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
chr11_+_20543307 0.53 ENSMUST00000093292.4
SERTA domain containing 2
chr4_-_41723129 0.53 ENSMUST00000171641.1
ENSMUST00000030158.4
dynactin 3
chr2_-_45117349 0.52 ENSMUST00000176438.2
zinc finger E-box binding homeobox 2
chr6_+_134981998 0.52 ENSMUST00000167323.1
apolipoprotein L domain containing 1
chr11_-_79962374 0.52 ENSMUST00000108241.1
ENSMUST00000043152.5
UTP6, small subunit (SSU) processome component, homolog (yeast)
chr14_-_18893376 0.52 ENSMUST00000151926.1
ubiquitin-conjugating enzyme E2E 2
chr16_+_56477838 0.50 ENSMUST00000048471.7
ENSMUST00000096013.3
ENSMUST00000096012.3
ENSMUST00000171000.1
ABI gene family, member 3 (NESH) binding protein
chr4_+_48663502 0.50 ENSMUST00000030033.4
muscle-related coiled-coil protein
chr2_+_3114220 0.50 ENSMUST00000072955.5
family with sequence similarity 171, member A1
chr8_-_36953139 0.48 ENSMUST00000179501.1
deleted in liver cancer 1
chr5_-_62766153 0.48 ENSMUST00000076623.4
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr4_-_96785186 0.48 ENSMUST00000107071.1
predicted gene 12695
chr8_+_117095854 0.48 ENSMUST00000034308.8
ENSMUST00000167370.1
ENSMUST00000176860.1
beta-carotene 15,15'-monooxygenase
chr9_+_106368594 0.48 ENSMUST00000172306.2
dual specificity phosphatase 7
chr19_+_43612299 0.48 ENSMUST00000057178.9
NK2 homeobox 3
chr11_+_96351632 0.48 ENSMUST00000100523.5
homeobox B2
chr18_+_34840575 0.46 ENSMUST00000043484.7
receptor accessory protein 2
chr1_+_132298606 0.46 ENSMUST00000046071.4
kelch domain containing 8A
chr11_+_94044111 0.45 ENSMUST00000132079.1
sperm associated antigen 9
chr3_+_55461758 0.45 ENSMUST00000070418.4
doublecortin-like kinase 1
chr3_+_10088173 0.44 ENSMUST00000061419.7
predicted gene 9833
chr3_+_51415986 0.44 ENSMUST00000029303.7
N(alpha)-acetyltransferase 15, NatA auxiliary subunit
chr7_+_101896817 0.44 ENSMUST00000143835.1
anaphase prompoting complex C subunit 15
chr9_+_46240696 0.44 ENSMUST00000034585.6
apolipoprotein A-IV
chr6_-_99044414 0.43 ENSMUST00000177507.1
ENSMUST00000123992.1
forkhead box P1
chr5_+_150756295 0.43 ENSMUST00000110486.1
PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)
chr11_+_24078173 0.43 ENSMUST00000109514.1
B cell CLL/lymphoma 11A (zinc finger protein)
chr16_-_3909192 0.43 ENSMUST00000181699.1
RIKEN cDNA 1700016D08 gene
chr17_+_27839974 0.42 ENSMUST00000071006.7
U1 small nuclear ribonucleoprotein C
chr16_+_14705832 0.41 ENSMUST00000023356.6
snail homolog 2 (Drosophila)
chr11_+_85312164 0.41 ENSMUST00000127717.1
protein phosphatase 1D magnesium-dependent, delta isoform
chr5_+_146948640 0.41 ENSMUST00000146511.1
ENSMUST00000132102.1
general transcription factor III A
chr2_-_45112890 0.41 ENSMUST00000076836.6
zinc finger E-box binding homeobox 2
chr3_+_87906842 0.40 ENSMUST00000159492.1
hepatoma-derived growth factor
chrX_+_97072596 0.40 ENSMUST00000033556.3
G protein-coupled receptor 15-like
chr4_+_140701466 0.40 ENSMUST00000038893.5
ENSMUST00000138808.1
regulator of chromosome condensation 2
chr15_-_77928925 0.39 ENSMUST00000109748.2
ENSMUST00000109747.2
ENSMUST00000100486.5
ENSMUST00000005487.5
thioredoxin 2
chr1_-_152625212 0.39 ENSMUST00000027760.7
ral guanine nucleotide dissociation stimulator,-like 1
chr3_-_86548268 0.39 ENSMUST00000077524.3
mab-21-like 2 (C. elegans)
chrM_+_7759 0.39 ENSMUST00000082407.1
ENSMUST00000082408.1
mitochondrially encoded ATP synthase 8
mitochondrially encoded ATP synthase 6
chrX_+_74127463 0.39 ENSMUST00000033771.4
ENSMUST00000101457.3
opsin 1 (cone pigments), medium-wave-sensitive (color blindness, deutan)
chrX_-_74249819 0.39 ENSMUST00000114299.1
filamin, alpha
chr8_+_45628176 0.39 ENSMUST00000130850.1
sorbin and SH3 domain containing 2
chr3_+_32515295 0.38 ENSMUST00000029203.7
zinc finger protein 639
chr1_-_165934900 0.38 ENSMUST00000069609.5
ENSMUST00000111427.2
ENSMUST00000111426.4
POU domain, class 2, transcription factor 1
chr4_-_110286581 0.37 ENSMUST00000138972.1
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr8_+_110618577 0.37 ENSMUST00000034190.9
Vac14 homolog (S. cerevisiae)
chr1_+_63176818 0.36 ENSMUST00000129339.1
eukaryotic translation elongation factor 1 beta 2
chrX_+_157699113 0.36 ENSMUST00000112521.1
small muscle protein, X-linked
chrX_+_153126897 0.36 ENSMUST00000163801.1
forkhead box R2
chr11_-_87359011 0.36 ENSMUST00000055438.4
protein phosphatase 1E (PP2C domain containing)
chr12_-_87443800 0.35 ENSMUST00000162961.1
alkB, alkylation repair homolog 1 (E. coli)
chr12_-_72408934 0.35 ENSMUST00000078505.7
reticulon 1
chr18_+_88971790 0.35 ENSMUST00000023828.7
rotatin
chr8_+_85432686 0.35 ENSMUST00000180883.1
RIKEN cDNA 1700051O22 Gene
chr13_-_75943812 0.34 ENSMUST00000022078.5
ENSMUST00000109606.1
Rho-related BTB domain containing 3
chr13_+_106947104 0.34 ENSMUST00000022203.8
DIM1 dimethyladenosine transferase 1-like (S. cerevisiae)
chr1_+_6730051 0.34 ENSMUST00000043578.6
ENSMUST00000131467.1
ENSMUST00000150761.1
ENSMUST00000151281.1
suppression of tumorigenicity 18
chr9_+_74953053 0.34 ENSMUST00000170846.1
family with sequence similarity 214, member A
chr5_+_92387846 0.33 ENSMUST00000138687.1
ENSMUST00000124509.1
ADP-ribosyltransferase 3
chrM_+_7005 0.33 ENSMUST00000082405.1
mitochondrially encoded cytochrome c oxidase II
chr11_-_93965957 0.33 ENSMUST00000021220.3
NME/NM23 nucleoside diphosphate kinase 1
chr1_+_183388981 0.33 ENSMUST00000097043.5
TATA box binding protein (Tbp)-associated factor, RNA polymerase I, A
chr10_+_106470281 0.33 ENSMUST00000029404.9
ENSMUST00000169303.1
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
chrM_+_5319 0.32 ENSMUST00000082402.1
mitochondrially encoded cytochrome c oxidase I
chr7_+_92819892 0.32 ENSMUST00000107180.1
ENSMUST00000107179.1
RAB30, member RAS oncogene family
chr5_-_84417359 0.32 ENSMUST00000113401.1
Eph receptor A5
chr17_+_37529957 0.31 ENSMUST00000097325.3
olfactory receptor 111
chr8_-_105637403 0.31 ENSMUST00000182046.1
predicted gene 5914
chr11_+_94044241 0.30 ENSMUST00000103168.3
sperm associated antigen 9
chr11_+_94044331 0.30 ENSMUST00000024979.8
sperm associated antigen 9
chr11_+_94044194 0.30 ENSMUST00000092777.4
ENSMUST00000075695.6
sperm associated antigen 9
chr2_-_20968526 0.30 ENSMUST00000141298.2
ENSMUST00000125783.2
Rho GTPase activating protein 21
chr4_+_59035088 0.30 ENSMUST00000041160.6
guanine nucleotide binding protein (G protein), gamma 10
chrX_-_23285532 0.30 ENSMUST00000115319.2
kelch-like 13
chr1_-_30863256 0.30 ENSMUST00000088310.3
PHD finger protein 3
chr8_-_84662841 0.29 ENSMUST00000060427.4
immediate early response 2
chr14_-_52237791 0.29 ENSMUST00000149975.1
chromodomain helicase DNA binding protein 8
chr18_+_37300799 0.28 ENSMUST00000051754.1
protocadherin beta 3
chr1_+_25830657 0.27 ENSMUST00000064487.1
predicted gene 9884
chr7_-_73541738 0.27 ENSMUST00000169922.2
chromodomain helicase DNA binding protein 2
chr4_-_59783800 0.27 ENSMUST00000107526.1
ENSMUST00000095063.4
INTS3 and NABP interacting protein
chr19_+_23723279 0.27 ENSMUST00000067077.1
predicted gene 9938
chr7_+_27553244 0.27 ENSMUST00000067386.7
RIKEN cDNA 2310022A10 gene
chr9_+_78051938 0.27 ENSMUST00000024104.7
glial cells missing homolog 1 (Drosophila)
chr12_-_83487708 0.26 ENSMUST00000177959.1
ENSMUST00000178756.1
D4, zinc and double PHD fingers, family 3
chr10_+_94576254 0.26 ENSMUST00000117929.1
transmembrane and coiled coil domains 3
chr1_-_190170671 0.26 ENSMUST00000175916.1
prospero-related homeobox 1
chr16_+_3909032 0.25 ENSMUST00000124849.1
clusterin associated protein 1
chr2_+_116067933 0.25 ENSMUST00000156095.1
RIKEN cDNA G630016G05 gene
chr7_-_132576372 0.25 ENSMUST00000084500.6
ornithine aminotransferase
chr5_-_99252839 0.24 ENSMUST00000168092.1
ENSMUST00000031276.8
RasGEF domain family, member 1B
chr2_-_79456750 0.24 ENSMUST00000041099.4
neurogenic differentiation 1
chrX_-_136741155 0.24 ENSMUST00000166930.1
ENSMUST00000113095.1
ENSMUST00000155207.1
ENSMUST00000080411.6
ENSMUST00000169418.1
mortality factor 4 like 2
chr14_-_20269162 0.24 ENSMUST00000024155.7
potassium channel, subfamily K, member 16
chr2_+_74704615 0.23 ENSMUST00000151380.1
homeobox D8
chr10_+_99263224 0.23 ENSMUST00000020118.4
dual specificity phosphatase 6
chr1_+_79776018 0.23 ENSMUST00000027464.8
mitochondrial ribosomal protein L44
chr4_+_48049080 0.23 ENSMUST00000153369.1
nuclear receptor subfamily 4, group A, member 3

Network of associatons between targets according to the STRING database.

First level regulatory network of Nkx2-3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.4 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.8 2.5 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
0.4 4.0 GO:0033227 dsRNA transport(GO:0033227)
0.4 1.3 GO:2000118 regulation of sodium-dependent phosphate transport(GO:2000118)
0.4 1.3 GO:0099543 positive regulation of circadian sleep/wake cycle, wakefulness(GO:0010841) retrograde trans-synaptic signaling(GO:0098917) trans-synaptic signaling by soluble gas(GO:0099543)
0.4 5.4 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.4 1.2 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.4 2.2 GO:0035864 response to potassium ion(GO:0035864) cellular response to potassium ion(GO:0035865) axonogenesis involved in innervation(GO:0060385)
0.3 6.9 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.3 0.8 GO:1903538 meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
0.2 0.7 GO:0007521 muscle cell fate determination(GO:0007521)
0.2 0.7 GO:0015881 creatine transport(GO:0015881)
0.2 0.8 GO:0035905 ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910)
0.2 1.0 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.2 1.2 GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987)
0.2 1.4 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.2 1.3 GO:0045213 neurotransmitter receptor metabolic process(GO:0045213)
0.2 0.9 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.2 0.9 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.2 0.9 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.2 0.5 GO:0021570 rhombomere 4 development(GO:0021570)
0.2 0.9 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.1 0.4 GO:0034443 regulation of lipoprotein oxidation(GO:0034442) negative regulation of lipoprotein oxidation(GO:0034443) multicellular organism lipid catabolic process(GO:0044240)
0.1 0.7 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.1 0.4 GO:1901420 negative regulation of response to alcohol(GO:1901420)
0.1 1.4 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.1 0.6 GO:0046684 response to pyrethroid(GO:0046684)
0.1 2.7 GO:0060539 diaphragm development(GO:0060539)
0.1 0.4 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.1 2.5 GO:2001014 regulation of skeletal muscle cell differentiation(GO:2001014)
0.1 0.6 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.1 0.2 GO:0038095 Fc-epsilon receptor signaling pathway(GO:0038095)
0.1 0.4 GO:0021508 floor plate formation(GO:0021508)
0.1 0.4 GO:1904799 negative regulation of dendrite extension(GO:1903860) regulation of neuron remodeling(GO:1904799) negative regulation of neuron remodeling(GO:1904800)
0.1 0.6 GO:0045218 zonula adherens maintenance(GO:0045218)
0.1 0.7 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.1 0.3 GO:0021759 globus pallidus development(GO:0021759)
0.1 1.1 GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.1 0.5 GO:0032596 protein transport into membrane raft(GO:0032596)
0.1 0.5 GO:0038032 termination of G-protein coupled receptor signaling pathway(GO:0038032)
0.1 0.4 GO:0035552 tRNA wobble cytosine modification(GO:0002101) oxidative single-stranded DNA demethylation(GO:0035552)
0.1 0.2 GO:0002874 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.1 0.5 GO:0002317 plasma cell differentiation(GO:0002317)
0.1 0.2 GO:2000979 hepatocyte cell migration(GO:0002194) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.1 0.4 GO:0030910 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.1 1.4 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
0.1 0.2 GO:1904578 response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579)
0.1 0.9 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.1 0.2 GO:1903002 regulation of lipid transport across blood brain barrier(GO:1903000) positive regulation of lipid transport across blood brain barrier(GO:1903002)
0.1 0.4 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.1 0.3 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.1 0.5 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.1 2.5 GO:0048745 smooth muscle tissue development(GO:0048745)
0.1 0.4 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1 1.0 GO:0019236 response to pheromone(GO:0019236)
0.1 0.2 GO:0003347 epicardial cell to mesenchymal cell transition(GO:0003347)
0.1 0.3 GO:0051684 maintenance of Golgi location(GO:0051684)
0.1 0.2 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.1 0.2 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.1 0.2 GO:1902159 regulation of cyclic nucleotide-gated ion channel activity(GO:1902159)
0.1 1.0 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.1 0.4 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.1 0.9 GO:0031507 heterochromatin assembly(GO:0031507)
0.1 0.6 GO:0090266 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.1 0.1 GO:0060220 camera-type eye photoreceptor cell fate commitment(GO:0060220)
0.1 0.8 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.2 GO:0061146 Peyer's patch morphogenesis(GO:0061146)
0.0 0.3 GO:0071372 response to follicle-stimulating hormone(GO:0032354) cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.0 0.2 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.3 GO:0021779 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.0 1.1 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.6 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.1 GO:0072708 response to sorbitol(GO:0072708)
0.0 0.6 GO:0080111 DNA demethylation(GO:0080111)
0.0 0.1 GO:0016095 polyprenol catabolic process(GO:0016095)
0.0 1.4 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.0 0.4 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.0 0.1 GO:0009744 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.0 1.5 GO:0016572 histone phosphorylation(GO:0016572)
0.0 0.1 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.0 0.2 GO:0034214 protein hexamerization(GO:0034214)
0.0 0.4 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.8 GO:1903392 negative regulation of adherens junction organization(GO:1903392)
0.0 0.7 GO:1900746 regulation of vascular endothelial growth factor signaling pathway(GO:1900746)
0.0 0.3 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.1 GO:0015867 ATP transport(GO:0015867)
0.0 0.2 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.0 0.1 GO:1900045 negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915)
0.0 0.8 GO:0010842 retina layer formation(GO:0010842)
0.0 0.3 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.8 GO:0044705 mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.0 0.8 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.0 0.3 GO:2000270 positive regulation of transcription from RNA polymerase III promoter(GO:0045945) negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 0.1 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.0 0.2 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.2 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.1 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.4 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.0 0.1 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.0 1.1 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.6 GO:0030903 notochord development(GO:0030903)
0.0 0.7 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.2 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.0 0.4 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.7 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.0 0.5 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.1 GO:0051798 positive regulation of hair follicle development(GO:0051798)
0.0 0.3 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.7 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.0 0.2 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.2 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0 0.7 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.2 GO:0033327 Leydig cell differentiation(GO:0033327)
0.0 0.1 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.1 GO:0050812 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.0 0.3 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 0.4 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.6 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.2 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.6 GO:0006182 cGMP biosynthetic process(GO:0006182)
0.0 0.2 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 2.4 GO:0007519 skeletal muscle tissue development(GO:0007519)
0.0 0.1 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.0 0.1 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.1 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.7 GO:0007588 excretion(GO:0007588)
0.0 0.3 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 0.5 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.3 GO:0000154 rRNA modification(GO:0000154)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 6.9 GO:0071439 clathrin complex(GO:0071439)
0.3 1.2 GO:0031523 Myb complex(GO:0031523)
0.3 1.0 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.2 1.2 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.2 1.5 GO:0001940 male pronucleus(GO:0001940)
0.2 1.4 GO:0005818 aster(GO:0005818)
0.1 0.9 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.1 1.1 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.1 1.2 GO:1990023 mitotic spindle midzone(GO:1990023)
0.1 1.4 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.1 1.0 GO:0016272 prefoldin complex(GO:0016272)
0.1 0.8 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 1.7 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 0.5 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.1 0.3 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.1 3.4 GO:0043034 costamere(GO:0043034)
0.1 0.7 GO:0005677 chromatin silencing complex(GO:0005677)
0.1 0.2 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.1 0.4 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.1 0.9 GO:0008385 IkappaB kinase complex(GO:0008385)
0.1 1.3 GO:0016580 Sin3 complex(GO:0016580)
0.1 0.4 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1 0.8 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 0.2 GO:0030934 collagen type XII trimer(GO:0005595) anchoring collagen complex(GO:0030934)
0.1 0.4 GO:0031415 NatA complex(GO:0031415)
0.1 0.3 GO:0070876 SOSS complex(GO:0070876)
0.1 0.6 GO:0005915 zonula adherens(GO:0005915)
0.0 0.2 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.0 0.4 GO:0000243 commitment complex(GO:0000243)
0.0 0.2 GO:0060187 cell pole(GO:0060187)
0.0 1.0 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.6 GO:0005869 dynactin complex(GO:0005869)
0.0 0.8 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.4 GO:0097542 ciliary tip(GO:0097542)
0.0 0.6 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.7 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 2.0 GO:0098878 ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.0 0.4 GO:0042627 chylomicron(GO:0042627)
0.0 0.4 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.2 GO:0042382 paraspeckles(GO:0042382)
0.0 0.6 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.2 GO:0001740 Barr body(GO:0001740)
0.0 0.6 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.8 GO:0030673 axolemma(GO:0030673)
0.0 0.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 1.2 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 2.5 GO:0001650 fibrillar center(GO:0001650)
0.0 0.5 GO:0097440 apical dendrite(GO:0097440)
0.0 0.4 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.1 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 0.2 GO:1902562 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.4 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.7 4.0 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.3 1.3 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.3 1.3 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.3 1.9 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.3 1.0 GO:0016748 succinyltransferase activity(GO:0016748)
0.3 2.8 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.2 1.2 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.2 0.7 GO:0005308 creatine transmembrane transporter activity(GO:0005308)
0.2 1.0 GO:0050816 phosphothreonine binding(GO:0050816)
0.2 0.9 GO:0008384 IkappaB kinase activity(GO:0008384)
0.2 0.7 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.2 1.4 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.1 1.1 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.1 0.4 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.1 0.9 GO:0005499 vitamin D binding(GO:0005499)
0.1 0.3 GO:0008988 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179) rRNA (adenine-N6-)-methyltransferase activity(GO:0008988)
0.1 0.8 GO:0033592 RNA strand annealing activity(GO:0033592)
0.1 0.6 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 0.7 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.1 0.6 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 0.5 GO:0042296 ISG15 transferase activity(GO:0042296)
0.1 1.2 GO:0043522 leucine zipper domain binding(GO:0043522)
0.1 0.4 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.1 1.2 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.1 0.4 GO:0043734 DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.1 0.5 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 0.4 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1 1.2 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.1 0.4 GO:0001851 complement component C3b binding(GO:0001851)
0.1 0.6 GO:0070097 delta-catenin binding(GO:0070097)
0.1 0.7 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.1 GO:0004948 calcitonin receptor activity(GO:0004948)
0.0 0.2 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.0 0.1 GO:0071077 coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.0 1.4 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.4 GO:1990446 U1 snRNP binding(GO:1990446)
0.0 0.7 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.7 GO:0015197 peptide transporter activity(GO:0015197)
0.0 0.2 GO:0032296 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0 1.0 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 1.1 GO:0005234 extracellular-glutamate-gated ion channel activity(GO:0005234)
0.0 0.4 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 1.1 GO:0008483 transaminase activity(GO:0008483)
0.0 0.2 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.2 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.2 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.0 0.2 GO:0005113 patched binding(GO:0005113)
0.0 0.3 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 1.2 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.2 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.4 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.4 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.6 GO:0031402 sodium ion binding(GO:0031402)
0.0 1.4 GO:0097472 cyclin-dependent protein kinase activity(GO:0097472)
0.0 0.3 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.5 GO:0017166 vinculin binding(GO:0017166)
0.0 0.9 GO:0070412 R-SMAD binding(GO:0070412)
0.0 1.5 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.7 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.1 GO:0009378 four-way junction helicase activity(GO:0009378)
0.0 0.3 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 0.6 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.2 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.6 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 1.6 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.1 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.4 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 1.5 GO:0005518 collagen binding(GO:0005518)
0.0 0.1 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.4 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 7.4 GO:0005543 phospholipid binding(GO:0005543)
0.0 1.2 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.1 GO:0031013 troponin I binding(GO:0031013)
0.0 0.8 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.2 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.0 0.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.1 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.0 1.0 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.1 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.0 0.1 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.2 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.1 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.4 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.5 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.1 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 2.8 GO:0051015 actin filament binding(GO:0051015)
0.0 1.5 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.0 0.2 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 4.1 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 0.2 GO:0051400 BH domain binding(GO:0051400)
0.0 0.7 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.7 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 1.0 GO:0051087 chaperone binding(GO:0051087)
0.0 0.7 GO:0017022 myosin binding(GO:0017022)
0.0 0.5 GO:0001965 G-protein alpha-subunit binding(GO:0001965)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.8 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 1.5 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 1.3 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 2.8 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.9 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 3.4 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 1.1 PID IL23 PATHWAY IL23-mediated signaling events
0.0 1.4 PID AURORA A PATHWAY Aurora A signaling
0.0 0.8 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 1.0 PID MYC PATHWAY C-MYC pathway
0.0 0.7 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 1.2 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 1.6 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.7 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.7 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 1.2 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 1.1 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.8 PID INSULIN PATHWAY Insulin Pathway
0.0 0.8 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.8 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.8 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.4 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.5 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.2 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.2 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.2 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.4 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.6 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.2 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 0.9 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.1 1.3 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.8 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.7 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 1.0 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 0.4 REACTOME OPSINS Genes involved in Opsins
0.0 0.7 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 1.0 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 1.1 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.7 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.7 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.8 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.4 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 1.0 REACTOME PROTEIN FOLDING Genes involved in Protein folding
0.0 2.5 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.7 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.4 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 2.1 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.2 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.3 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.5 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.4 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.3 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.3 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.8 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.2 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport