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12D miR HR13_24

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Results for Lhx4

Z-value: 0.85

Motif logo

Transcription factors associated with Lhx4

Gene Symbol Gene ID Gene Info
ENSMUSG00000026468.8 LIM homeobox protein 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Lhx4mm10_v2_chr1_-_155742120_155742136-0.614.7e-02Click!

Activity profile of Lhx4 motif

Sorted Z-values of Lhx4 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_96115249 1.26 ENSMUST00000075080.5
family with sequence similarity 19, member A1
chr16_-_22161450 1.23 ENSMUST00000115379.1
insulin-like growth factor 2 mRNA binding protein 2
chr4_+_102589687 1.20 ENSMUST00000097949.4
ENSMUST00000106901.1
phosphodiesterase 4B, cAMP specific
chr19_+_5474681 1.07 ENSMUST00000165485.1
ENSMUST00000166253.1
ENSMUST00000167371.1
ENSMUST00000167855.1
ENSMUST00000070118.7
epidermal growth factor-containing fibulin-like extracellular matrix protein 2
chr14_-_110755100 0.97 ENSMUST00000078386.2
SLIT and NTRK-like family, member 6
chr4_+_145585166 0.93 ENSMUST00000105739.1
ENSMUST00000119718.1
predicted gene 13212
chr4_-_45532470 0.78 ENSMUST00000147448.1
src homology 2 domain-containing transforming protein B
chr11_+_59306920 0.76 ENSMUST00000000128.3
ENSMUST00000108783.3
wingless-type MMTV integration site 9A
chr7_+_45621805 0.76 ENSMUST00000033100.4
izumo sperm-egg fusion 1
chr4_-_147702553 0.68 ENSMUST00000117638.1
zinc finger protein 534
chr12_-_40199315 0.66 ENSMUST00000095760.2
leucine-rich single-pass membrane protein 1
chr15_+_31224371 0.63 ENSMUST00000044524.9
death-associated protein
chr3_-_59220150 0.58 ENSMUST00000170388.1
purinergic receptor P2Y, G-protein coupled 12
chr16_-_44016387 0.57 ENSMUST00000036174.3
GRAM domain containing 1C
chr13_+_67833235 0.57 ENSMUST00000060609.7
predicted gene 10037
chr1_-_162866502 0.56 ENSMUST00000046049.7
flavin containing monooxygenase 1
chr6_-_129385497 0.55 ENSMUST00000032261.6
C-type lectin domain family 12, member B
chr10_-_20548320 0.54 ENSMUST00000169404.1
phosphodiesterase 7B
chr7_+_140941550 0.52 ENSMUST00000079403.4
ATH1, acid trehalase-like 1 (yeast)
chr6_-_115592571 0.50 ENSMUST00000112957.1
RIKEN cDNA 2510049J12 gene
chr17_+_17402672 0.50 ENSMUST00000115576.2
limb expression 1 homolog (chicken)
chr15_+_34453285 0.49 ENSMUST00000060894.7
cDNA sequence BC030476
chr15_+_98571004 0.49 ENSMUST00000023728.6
RIKEN cDNA 4930415O20 gene
chr6_-_3399545 0.48 ENSMUST00000120087.3
sterile alpha motif domain containing 9-like
chr12_-_12941827 0.46 ENSMUST00000043396.7
v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)
chr10_-_20548361 0.46 ENSMUST00000164195.1
phosphodiesterase 7B
chr11_+_62847111 0.46 ENSMUST00000150989.1
ENSMUST00000176577.1
F-box and WD-40 domain protein 10
chr6_+_38381469 0.45 ENSMUST00000162554.1
ENSMUST00000161751.1
tetratricopeptide repeat domain 26
chr2_-_63184253 0.43 ENSMUST00000075052.3
ENSMUST00000112454.1
potassium voltage-gated channel, subfamily H (eag-related), member 7
chr4_-_19922599 0.42 ENSMUST00000029900.5
ATPase, H+ transporting, lysosomal V0 subunit D2
chr7_-_102714411 0.42 ENSMUST00000084817.2
olfactory receptor 33
chr9_+_72958785 0.41 ENSMUST00000098567.2
ENSMUST00000034734.8
dyslexia susceptibility 1 candidate 1 homolog (human)
chr17_-_36032682 0.41 ENSMUST00000102678.4
histocompatibility 2, T region locus 23
chr3_+_41742615 0.40 ENSMUST00000146165.1
ENSMUST00000119572.1
ENSMUST00000108065.2
ENSMUST00000120167.1
ENSMUST00000026867.7
ENSMUST00000026868.7
DNA segment, Chr 3, ERATO Doi 751, expressed
chr18_-_66860458 0.39 ENSMUST00000057942.2
melanocortin 4 receptor
chr11_+_67798269 0.38 ENSMUST00000168612.1
ENSMUST00000040574.4
dehydrogenase/reductase (SDR family) member 7C
chr6_+_29859662 0.38 ENSMUST00000128927.2
S-adenosylhomocysteine hydrolase-like 2
chr9_-_96437434 0.38 ENSMUST00000070500.2
cDNA sequence BC043934
chr14_+_27000362 0.38 ENSMUST00000035433.8
homeobox gene expressed in ES cells
chr3_-_85741389 0.38 ENSMUST00000094148.4
family with sequence similarity 160, member A1
chr4_+_145514884 0.37 ENSMUST00000105741.1
predicted gene 13225
chr2_+_23069210 0.37 ENSMUST00000155602.1
acyl-Coenzyme A binding domain containing 5
chr6_+_29859374 0.36 ENSMUST00000115238.3
S-adenosylhomocysteine hydrolase-like 2
chr8_+_34807287 0.36 ENSMUST00000033930.4
dual specificity phosphatase 4
chr10_+_75037066 0.36 ENSMUST00000147802.1
ENSMUST00000020391.5
RAB36, member RAS oncogene family
chr6_+_29859686 0.35 ENSMUST00000134438.1
S-adenosylhomocysteine hydrolase-like 2
chr10_-_64090265 0.35 ENSMUST00000105439.1
leucine rich repeat transmembrane neuronal 3
chr6_+_34780412 0.35 ENSMUST00000115016.1
ENSMUST00000115017.1
ATP/GTP binding protein-like 3
chr1_-_72284248 0.34 ENSMUST00000097698.4
ENSMUST00000027381.6
peroxisomal trans-2-enoyl-CoA reductase
chrX_-_139871637 0.34 ENSMUST00000033811.7
ENSMUST00000087401.5
microrchidia 4
chr9_-_40962333 0.34 ENSMUST00000160120.1
RIKEN cDNA 4931429I11 gene
chr10_+_116964707 0.34 ENSMUST00000176050.1
ENSMUST00000176455.1
RIKEN cDNA D630029K05 gene
chr7_-_49636847 0.34 ENSMUST00000032717.6
developing brain homeobox 1
chr15_+_25752860 0.34 ENSMUST00000022882.5
ENSMUST00000135173.1
myosin X
chr13_-_52530827 0.34 ENSMUST00000057442.6
DIRAS family, GTP-binding RAS-like 2
chr4_+_145510759 0.34 ENSMUST00000105742.1
ENSMUST00000136309.1
predicted gene 13225
chr18_-_38866702 0.33 ENSMUST00000115582.1
fibroblast growth factor 1
chr4_+_147553277 0.33 ENSMUST00000139784.1
ENSMUST00000143885.1
ENSMUST00000081742.6
predicted gene 13154
chr11_+_62847062 0.33 ENSMUST00000036085.4
F-box and WD-40 domain protein 10
chr4_+_146097312 0.33 ENSMUST00000105730.1
ENSMUST00000091878.5
predicted gene 13051
chr14_+_80000292 0.32 ENSMUST00000088735.3
olfactomedin 4
chr4_-_147809788 0.32 ENSMUST00000105734.3
ENSMUST00000176201.1
predicted gene 13157
predicted gene 20707
chr5_+_29195983 0.32 ENSMUST00000160888.1
ENSMUST00000159272.1
ENSMUST00000001247.5
ENSMUST00000161398.1
ENSMUST00000160246.1
ring finger protein 32
chr4_+_146161909 0.32 ENSMUST00000131932.1
zinc finger protein 600
chr15_-_42676967 0.31 ENSMUST00000022921.5
angiopoietin 1
chr1_-_9298499 0.31 ENSMUST00000132064.1
syntrophin, gamma 1
chr5_-_62765618 0.30 ENSMUST00000159470.1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr1_-_74885322 0.30 ENSMUST00000159232.1
ENSMUST00000068631.3
FEV (ETS oncogene family)
chr6_-_129876659 0.30 ENSMUST00000014687.4
ENSMUST00000122219.1
killer cell lectin-like receptor, subfamily A, member 17
chr10_+_116966274 0.29 ENSMUST00000033651.3
RIKEN cDNA D630029K05 gene
chr4_-_58499398 0.29 ENSMUST00000107570.1
lysophosphatidic acid receptor 1
chr2_+_125136692 0.29 ENSMUST00000099452.2
cortexin 2
chr17_-_34862473 0.29 ENSMUST00000025229.4
ENSMUST00000176203.2
ENSMUST00000128767.1
complement factor B
chrX_-_143933204 0.28 ENSMUST00000112851.1
ENSMUST00000112856.2
ENSMUST00000033642.3
doublecortin
chr1_-_127840290 0.28 ENSMUST00000061512.2
mitogen-activated protein kinase kinase kinase 19
chr6_-_13871459 0.28 ENSMUST00000155856.1
RIKEN cDNA 2610001J05 gene
chr1_-_9299238 0.28 ENSMUST00000140295.1
syntrophin, gamma 1
chr17_-_34862122 0.28 ENSMUST00000154526.1
complement factor B
chr2_+_83724397 0.27 ENSMUST00000028499.4
ENSMUST00000141725.1
ENSMUST00000111740.2
integrin alpha V
chr17_-_67950908 0.27 ENSMUST00000164647.1
Rho GTPase activating protein 28
chr6_-_128275577 0.27 ENSMUST00000130454.1
TEA domain family member 4
chr4_+_145670685 0.27 ENSMUST00000105738.2
predicted gene 13242
chr6_-_29507946 0.27 ENSMUST00000101614.3
ENSMUST00000078112.6
kielin/chordin-like protein
chr5_-_70842617 0.27 ENSMUST00000031119.1
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1
chr6_+_30611029 0.27 ENSMUST00000115138.1
carboxypeptidase A5
chr18_+_57468478 0.27 ENSMUST00000091892.2
cortexin 3
chr1_+_72284367 0.26 ENSMUST00000027380.5
ENSMUST00000141783.1
transmembrane protein 169
chr16_-_22857514 0.26 ENSMUST00000004576.6
TBCC domain containing 1
chr6_+_30610984 0.26 ENSMUST00000062758.4
carboxypeptidase A5
chr16_-_64771146 0.26 ENSMUST00000076991.6
RIKEN cDNA 4930453N24 gene
chr6_-_41377604 0.26 ENSMUST00000096003.5
protease, serine, 3
chr9_+_119063429 0.25 ENSMUST00000141185.1
ENSMUST00000126251.1
ENSMUST00000136561.1
villin-like
chrX_-_143933089 0.25 ENSMUST00000087313.3
doublecortin
chr16_+_43235856 0.25 ENSMUST00000146708.1
zinc finger and BTB domain containing 20
chr13_-_105271039 0.24 ENSMUST00000069686.6
ring finger protein 180
chr16_-_45844228 0.24 ENSMUST00000076333.5
pleckstrin homology-like domain, family B, member 2
chr11_-_49113757 0.24 ENSMUST00000060398.1
olfactory receptor 1396
chr4_-_97778042 0.24 ENSMUST00000146447.1
RIKEN cDNA E130114P18 gene
chr16_-_76022266 0.24 ENSMUST00000114240.1
SAM domain, SH3 domain and nuclear localization signals, 1
chr3_-_141982224 0.24 ENSMUST00000029948.8
bone morphogenetic protein receptor, type 1B
chr5_+_20702129 0.23 ENSMUST00000101556.4
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr5_+_9266097 0.23 ENSMUST00000134991.1
ENSMUST00000069538.7
ENSMUST00000115348.2
RIKEN cDNA 9330182L06 gene
chr17_-_56036546 0.23 ENSMUST00000003268.9
SH3-domain GRB2-like 1
chr4_+_65124174 0.23 ENSMUST00000084501.3
pregnancy-associated plasma protein A
chr16_-_45844303 0.22 ENSMUST00000036355.6
pleckstrin homology-like domain, family B, member 2
chr6_-_41446062 0.22 ENSMUST00000095999.5
predicted gene 10334
chr16_+_48283735 0.22 ENSMUST00000096045.1
ENSMUST00000050705.2
developmental pluripotency associated 4
chr13_-_100446406 0.22 ENSMUST00000022142.5
NLR family, apoptosis inhibitory protein 1
chr13_-_102906046 0.22 ENSMUST00000171791.1
microtubule associated serine/threonine kinase family member 4
chr2_-_170194033 0.22 ENSMUST00000180625.1
predicted gene, 17619
chr7_-_37772868 0.22 ENSMUST00000176205.1
zinc finger protein 536
chrX_+_160768013 0.21 ENSMUST00000033650.7
retinoschisis (X-linked, juvenile) 1 (human)
chr1_+_180111339 0.21 ENSMUST00000145181.1
CDC42 binding protein kinase alpha
chr13_-_102905740 0.21 ENSMUST00000167462.1
microtubule associated serine/threonine kinase family member 4
chr2_+_4300462 0.21 ENSMUST00000175669.1
FERM domain containing 4A
chr12_+_10390756 0.21 ENSMUST00000020947.5
retinol dehydrogenase 14 (all-trans and 9-cis)
chr17_-_46032366 0.20 ENSMUST00000071648.5
ENSMUST00000142351.2
ENSMUST00000167860.1
vascular endothelial growth factor A
chr7_-_37769624 0.20 ENSMUST00000175941.1
zinc finger protein 536
chr4_-_35845204 0.20 ENSMUST00000164772.1
ENSMUST00000065173.2
leucine rich repeat and Ig domain containing 2
chr18_-_56975333 0.20 ENSMUST00000139243.2
ENSMUST00000025488.8
RIKEN cDNA C330018D20 gene
chr14_-_48665098 0.20 ENSMUST00000118578.1
orthodenticle homolog 2 (Drosophila)
chr3_-_116711820 0.20 ENSMUST00000153108.1
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member 3
chr17_-_46031813 0.20 ENSMUST00000024747.7
vascular endothelial growth factor A
chr3_-_41742471 0.20 ENSMUST00000026866.8
sodium channel and clathrin linker 1
chr9_-_104337700 0.19 ENSMUST00000112590.2
ENSMUST00000062723.6
acid phosphatase, prostate
chr10_-_24101951 0.19 ENSMUST00000170267.1
trace amine-associated receptor 8C
chr7_-_8931402 0.19 ENSMUST00000169206.3
ENSMUST00000171942.2
vomeronasal 2, receptor 40
chr1_+_177444653 0.19 ENSMUST00000094276.3
zinc finger and BTB domain containing 18
chr18_-_15403680 0.19 ENSMUST00000079081.6
aquaporin 4
chr5_+_19907502 0.19 ENSMUST00000101558.3
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr5_-_17888884 0.19 ENSMUST00000169095.1
CD36 antigen
chr9_+_108339048 0.19 ENSMUST00000082429.5
glutathione peroxidase 1
chr3_+_135348029 0.19 ENSMUST00000159658.1
ENSMUST00000078568.5
ENSMUST00000160460.1
solute carrier family 9, subfamily B (NHA1, cation proton antiporter 1), member 1
chr10_+_116143881 0.19 ENSMUST00000105271.2
protein tyrosine phosphatase, receptor type, R
chr7_+_30458280 0.18 ENSMUST00000126297.1
nephrosis 1, nephrin
chr14_+_26122609 0.18 ENSMUST00000100810.6
doubl homeobox B-like 2
chr11_-_73326472 0.18 ENSMUST00000155630.2
aspartoacylase
chr10_-_62507737 0.18 ENSMUST00000020271.6
serglycin
chr16_-_16829276 0.18 ENSMUST00000023468.5
sperm associated antigen 6
chr5_-_108795352 0.18 ENSMUST00000004943.1
transmembrane emp24 protein transport domain containing
chr7_-_5014645 0.17 ENSMUST00000165320.1
Flt3 interacting zinc finger protein 1
chr11_-_98329641 0.17 ENSMUST00000041685.6
neurogenic differentiation 2
chr3_+_142620596 0.17 ENSMUST00000165774.1
guanylate binding protein 2
chrX_-_75578188 0.17 ENSMUST00000033545.5
RAB39B, member RAS oncogene family
chr6_+_7555053 0.17 ENSMUST00000090679.2
ENSMUST00000184986.1
tachykinin 1
chr17_-_78684262 0.16 ENSMUST00000145480.1
striatin, calmodulin binding protein
chr15_-_8710409 0.16 ENSMUST00000157065.1
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr10_+_102158858 0.16 ENSMUST00000138522.1
ENSMUST00000163753.1
ENSMUST00000138016.1
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr15_-_8710734 0.16 ENSMUST00000005493.7
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr8_-_106573461 0.16 ENSMUST00000073722.5
predicted pseudogene 10073
chr15_-_36879816 0.16 ENSMUST00000100713.2
predicted gene 10384
chr1_-_89933290 0.16 ENSMUST00000036954.7
gastrulation brain homeobox 2
chr2_-_7396192 0.16 ENSMUST00000137733.2
CUGBP, Elav-like family member 2
chr2_-_33942111 0.15 ENSMUST00000130988.1
ENSMUST00000127936.1
ENSMUST00000134271.1
predicted gene 13403
chr15_-_93595877 0.15 ENSMUST00000048982.4
prickle homolog 1 (Drosophila)
chr16_+_11406618 0.15 ENSMUST00000122168.1
sorting nexin 29
chr5_-_28210022 0.14 ENSMUST00000118882.1
canopy 1 homolog (zebrafish)
chr16_-_74411292 0.14 ENSMUST00000117200.1
roundabout homolog 2 (Drosophila)
chr4_+_116596672 0.14 ENSMUST00000051869.7
coiled-coil domain containing 17
chr1_-_93445642 0.14 ENSMUST00000042498.7
high density lipoprotein (HDL) binding protein
chr18_+_55057557 0.14 ENSMUST00000181765.1
predicted gene 4221
chr2_-_63184170 0.14 ENSMUST00000112452.1
potassium voltage-gated channel, subfamily H (eag-related), member 7
chr1_+_88055377 0.14 ENSMUST00000138182.1
ENSMUST00000113142.3
UDP glycosyltransferase 1 family, polypeptide A10
chr13_-_97747373 0.14 ENSMUST00000123535.1
RIKEN cDNA 5330416C01 gene
chr2_-_7395879 0.14 ENSMUST00000182404.1
CUGBP, Elav-like family member 2
chr7_+_66839752 0.13 ENSMUST00000107478.1
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 17
chr7_-_7689513 0.13 ENSMUST00000173459.1
vomeronasal 2, receptor 34
chr7_-_7902462 0.13 ENSMUST00000170402.2
vomeronasal 2, receptor 36
chr2_+_86007778 0.13 ENSMUST00000062166.1
olfactory receptor 1032
chr5_+_19907774 0.13 ENSMUST00000115267.2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr4_-_3938354 0.13 ENSMUST00000003369.3
pleiomorphic adenoma gene 1
chr10_+_23797052 0.13 ENSMUST00000133289.1
solute carrier family 18, subfamily B, member 1
chr14_+_75455957 0.12 ENSMUST00000164848.1
seven in absentia homolog 3 (Drosophila)
chr6_-_138079916 0.12 ENSMUST00000171804.1
solute carrier family 15, member 5
chr4_+_97777780 0.12 ENSMUST00000107062.2
ENSMUST00000052018.5
ENSMUST00000107057.1
nuclear factor I/A
chr11_-_31671727 0.12 ENSMUST00000109415.1
biorientation of chromosomes in cell division 1
chr9_+_118478182 0.12 ENSMUST00000111763.1
eomesodermin homolog (Xenopus laevis)
chr6_+_72097561 0.12 ENSMUST00000069994.4
ENSMUST00000114112.1
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
chr13_+_120308146 0.12 ENSMUST00000081558.7
cDNA sequence BC147527
chr1_-_133661318 0.12 ENSMUST00000179598.1
ENSMUST00000027736.6
zinc finger, BED domain containing 6
zinc finger CCCH type containing 11A
chr16_-_29544852 0.12 ENSMUST00000039090.8
ATPase type 13A4
chr1_+_88055467 0.12 ENSMUST00000173325.1
UDP glycosyltransferase 1 family, polypeptide A10
chr5_-_28210168 0.12 ENSMUST00000117098.1
canopy 1 homolog (zebrafish)
chr10_+_75566257 0.12 ENSMUST00000129232.1
ENSMUST00000143792.1
gamma-glutamyltransferase 1
chr11_+_60537978 0.11 ENSMUST00000044250.3
alkB, alkylation repair homolog 5 (E. coli)
chr8_-_24725762 0.11 ENSMUST00000171438.1
ENSMUST00000171611.1
ENSMUST00000033958.7
a disintegrin and metallopeptidase domain 3 (cyritestin)
chr10_+_75037291 0.11 ENSMUST00000139384.1
RAB36, member RAS oncogene family
chr2_-_155945282 0.11 ENSMUST00000040162.2
growth differentiation factor 5
chr1_-_22315792 0.11 ENSMUST00000164877.1
regulating synaptic membrane exocytosis 1
chr12_+_30884321 0.11 ENSMUST00000067087.6
family with sequence similarity 150, member B
chr18_+_38296805 0.11 ENSMUST00000171461.1
ring finger protein 14
chr7_-_8489075 0.11 ENSMUST00000164845.2
vomeronasal 2, receptor 45
chr12_-_27342696 0.11 ENSMUST00000079063.5
SRY-box containing gene 11
chr8_+_34054622 0.10 ENSMUST00000149618.1
predicted gene 9951
chr11_-_106973090 0.10 ENSMUST00000150366.1
predicted gene 11707
chr9_+_120929216 0.10 ENSMUST00000130466.1
catenin (cadherin associated protein), beta 1
chr12_-_103694657 0.10 ENSMUST00000117053.1
serine (or cysteine) peptidase inhibitor, clade A, member 1F
chr3_-_67515487 0.10 ENSMUST00000178314.1
ENSMUST00000054825.4
retinoic acid receptor responder (tazarotene induced) 1
chr1_+_106171752 0.10 ENSMUST00000061047.6
PH domain and leucine rich repeat protein phosphatase 1
chr19_-_45235811 0.10 ENSMUST00000099401.4
ladybird homeobox homolog 1 (Drosophila)

Network of associatons between targets according to the STRING database.

First level regulatory network of Lhx4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0060005 vestibular reflex(GO:0060005)
0.1 0.6 GO:1904139 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.1 0.6 GO:0002767 immune response-inhibiting cell surface receptor signaling pathway(GO:0002767)
0.1 1.1 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 0.4 GO:0038189 neuropilin signaling pathway(GO:0038189) VEGF-activated neuropilin signaling pathway(GO:0038190)
0.1 0.5 GO:0008594 photoreceptor cell morphogenesis(GO:0008594)
0.1 0.3 GO:0030210 heparin biosynthetic process(GO:0030210)
0.1 0.4 GO:2000566 antigen processing and presentation of endogenous peptide antigen via MHC class Ib(GO:0002476) antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway(GO:0002488) antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent(GO:0002489) positive regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000566)
0.1 1.2 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 0.3 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.1 0.3 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.1 0.8 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.1 0.3 GO:1904566 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.1 0.2 GO:0016062 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.1 0.8 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.1 0.5 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.1 0.3 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.1 0.3 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.1 0.2 GO:0042723 thiamine metabolic process(GO:0006772) thiamine-containing compound metabolic process(GO:0042723) positive regulation of adenosine receptor signaling pathway(GO:0060168)
0.1 0.2 GO:0070543 response to linoleic acid(GO:0070543)
0.1 0.6 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.1 0.2 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
0.1 0.2 GO:0033379 protein localization to secretory granule(GO:0033366) protein localization to mast cell secretory granule(GO:0033367) protease localization to mast cell secretory granule(GO:0033368) maintenance of protein location in mast cell secretory granule(GO:0033370) T cell secretory granule organization(GO:0033371) maintenance of protease location in mast cell secretory granule(GO:0033373) protein localization to T cell secretory granule(GO:0033374) protease localization to T cell secretory granule(GO:0033375) maintenance of protein location in T cell secretory granule(GO:0033377) maintenance of protease location in T cell secretory granule(GO:0033379) granzyme B localization to T cell secretory granule(GO:0033380) maintenance of granzyme B location in T cell secretory granule(GO:0033382)
0.1 0.2 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.1 0.3 GO:0001830 trophectodermal cell fate commitment(GO:0001830)
0.1 0.3 GO:0051661 maintenance of centrosome location(GO:0051661) maintenance of Golgi location(GO:0051684)
0.1 0.4 GO:0030242 pexophagy(GO:0030242)
0.0 0.1 GO:0051892 negative regulation of cardioblast differentiation(GO:0051892)
0.0 0.3 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.0 0.2 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.0 0.1 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.0 0.6 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.4 GO:0030916 otic vesicle formation(GO:0030916)
0.0 0.5 GO:2000980 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0 0.2 GO:2000851 positive regulation of glucocorticoid secretion(GO:2000851)
0.0 0.2 GO:0015788 UDP-N-acetylglucosamine transport(GO:0015788)
0.0 1.0 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.0 0.3 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.2 GO:0070295 renal water absorption(GO:0070295)
0.0 0.2 GO:0002378 immunoglobulin biosynthetic process(GO:0002378) regulation of hematopoietic stem cell migration(GO:2000471) positive regulation of hematopoietic stem cell migration(GO:2000473)
0.0 0.3 GO:0051611 regulation of serotonin uptake(GO:0051611)
0.0 0.6 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.4 GO:2000821 regulation of grooming behavior(GO:2000821)
0.0 0.5 GO:0036159 inner dynein arm assembly(GO:0036159)
0.0 0.5 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.2 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.0 0.2 GO:0006083 acetate metabolic process(GO:0006083)
0.0 0.1 GO:0072235 distal convoluted tubule development(GO:0072025) metanephric distal convoluted tubule development(GO:0072221) metanephric distal tubule development(GO:0072235)
0.0 0.1 GO:0035553 oxidative single-stranded RNA demethylation(GO:0035553)
0.0 0.4 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.2 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.1 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
0.0 0.1 GO:0061386 closure of optic fissure(GO:0061386)
0.0 0.4 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.0 0.3 GO:0048664 neuron fate determination(GO:0048664)
0.0 0.1 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.0 0.1 GO:1900369 negative regulation of RNA interference(GO:1900369)
0.0 0.4 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.3 GO:0030497 fatty acid elongation(GO:0030497)
0.0 0.2 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.0 0.1 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.0 0.3 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.0 0.1 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.0 0.2 GO:0018158 protein oxidation(GO:0018158)
0.0 0.2 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 0.0 GO:0009441 glycolate metabolic process(GO:0009441)
0.0 0.2 GO:0042415 norepinephrine metabolic process(GO:0042415)
0.0 0.2 GO:0060484 lung-associated mesenchyme development(GO:0060484)
0.0 0.5 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.4 GO:0007035 vacuolar acidification(GO:0007035)
0.0 0.1 GO:1901748 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.0 0.5 GO:0014808 release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0014808)
0.0 0.2 GO:1990001 inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.0 0.6 GO:0034198 cellular response to amino acid starvation(GO:0034198)
0.0 0.2 GO:0042572 retinol metabolic process(GO:0042572)
0.0 0.1 GO:0007207 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0034685 integrin alphav-beta5 complex(GO:0034684) integrin alphav-beta6 complex(GO:0034685)
0.0 1.2 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.7 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.4 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.4 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.8 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.2 GO:0097413 Lewy body(GO:0097413)
0.0 0.1 GO:0098831 presynaptic active zone cytoplasmic component(GO:0098831)
0.0 0.3 GO:0042581 specific granule(GO:0042581)
0.0 0.2 GO:0042629 mast cell granule(GO:0042629)
0.0 0.2 GO:0071439 clathrin complex(GO:0071439)
0.0 0.1 GO:0098642 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.0 0.4 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.3 GO:0045180 basal cortex(GO:0045180)
0.0 0.2 GO:0020005 symbiont-containing vacuole membrane(GO:0020005)
0.0 0.1 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.0 0.3 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.1 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.2 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 0.4 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1 0.4 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.1 0.4 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 0.3 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.1 0.8 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.1 0.6 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 0.6 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 0.2 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.1 2.2 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 0.2 GO:0019807 aspartoacylase activity(GO:0019807)
0.1 0.3 GO:0019960 C-X3-C chemokine binding(GO:0019960)
0.1 0.3 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 0.6 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.6 GO:0070513 death domain binding(GO:0070513)
0.0 0.3 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.4 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.7 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.3 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.9 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.9 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.6 GO:0030547 receptor inhibitor activity(GO:0030547)
0.0 0.1 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.0 0.2 GO:0033265 choline binding(GO:0033265)
0.0 0.2 GO:0015288 porin activity(GO:0015288)
0.0 0.3 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.4 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.1 GO:0003692 left-handed Z-DNA binding(GO:0003692)
0.0 0.3 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.2 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.4 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.2 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.2 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.6 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.2 GO:0008106 alcohol dehydrogenase (NADP+) activity(GO:0008106)
0.0 0.8 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.3 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.1 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.6 GO:0005109 frizzled binding(GO:0005109)
0.0 0.8 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.1 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 0.1 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.1 GO:0036122 BMP binding(GO:0036122)
0.0 0.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 1.0 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.6 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.5 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.5 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.6 ST JNK MAPK PATHWAY JNK MAPK Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.6 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.4 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.4 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 1.2 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.3 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.7 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.3 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.2 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.1 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.6 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.3 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.4 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.2 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.2 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.6 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.3 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation