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12D miR HR13_24

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Results for Nfatc3

Z-value: 1.01

Motif logo

Transcription factors associated with Nfatc3

Gene Symbol Gene ID Gene Info
ENSMUSG00000031902.9 nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nfatc3mm10_v2_chr8_+_106059562_1060596230.595.5e-02Click!

Activity profile of Nfatc3 motif

Sorted Z-values of Nfatc3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr10_+_4611971 5.56 ENSMUST00000105590.1
ENSMUST00000067086.7
estrogen receptor 1 (alpha)
chr9_+_88327592 2.26 ENSMUST00000034992.6
5' nucleotidase, ecto
chr6_+_21985903 1.80 ENSMUST00000137437.1
ENSMUST00000115383.2
cadherin-like and PC-esterase domain containing 1
chr6_+_21986438 1.71 ENSMUST00000115382.1
cadherin-like and PC-esterase domain containing 1
chr6_-_85513586 1.56 ENSMUST00000095759.3
early growth response 4
chr5_+_110330697 1.12 ENSMUST00000112481.1
polymerase (DNA directed), epsilon
chr12_-_72917760 1.07 ENSMUST00000110489.2
RIKEN cDNA 4930447C04 gene
chr12_+_91400990 1.05 ENSMUST00000021346.7
ENSMUST00000021343.6
thyroid stimulating hormone receptor
chr4_-_117125618 1.04 ENSMUST00000183310.1
BTB (POZ) domain containing 19
chr2_-_62573813 1.00 ENSMUST00000174234.1
ENSMUST00000000402.9
ENSMUST00000174448.1
fibroblast activation protein
chr2_+_157560078 0.98 ENSMUST00000153739.2
ENSMUST00000173595.1
ENSMUST00000109526.1
ENSMUST00000173839.1
ENSMUST00000173041.1
ENSMUST00000173793.1
ENSMUST00000172487.1
ENSMUST00000088484.5
neuronatin
chr3_+_94377432 0.91 ENSMUST00000107292.1
RAR-related orphan receptor gamma
chr4_-_43523595 0.88 ENSMUST00000107914.3
tropomyosin 2, beta
chr3_+_94377505 0.86 ENSMUST00000098877.2
RAR-related orphan receptor gamma
chr13_+_31806627 0.83 ENSMUST00000062292.2
forkhead box C1
chr10_+_7667503 0.80 ENSMUST00000040135.8
nucleoporin 43
chr5_-_148392810 0.73 ENSMUST00000138257.1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr19_-_10101501 0.72 ENSMUST00000025567.7
fatty acid desaturase 2
chr12_+_37241729 0.72 ENSMUST00000160768.1
alkylglycerol monooxygenase
chr4_-_43523746 0.71 ENSMUST00000150592.1
tropomyosin 2, beta
chr6_+_21986887 0.71 ENSMUST00000151315.1
cadherin-like and PC-esterase domain containing 1
chr11_+_99047311 0.71 ENSMUST00000140772.1
insulin-like growth factor binding protein 4
chr4_-_108406676 0.70 ENSMUST00000184609.1
glutathione peroxidase 7
chr3_-_33083016 0.70 ENSMUST00000078226.3
ENSMUST00000108224.1
peroxisomal biogenesis factor 5-like
chr19_+_53310495 0.67 ENSMUST00000003870.7
Max interacting protein 1
chr3_-_152266320 0.65 ENSMUST00000046045.8
nexilin
chr18_+_4994600 0.64 ENSMUST00000140448.1
supervillin
chr9_-_70934808 0.63 ENSMUST00000034731.8
lipase, hepatic
chr5_+_3343893 0.62 ENSMUST00000165117.1
cyclin-dependent kinase 6
chr16_-_4559720 0.60 ENSMUST00000005862.7
transcription factor AP4
chr19_-_57360668 0.60 ENSMUST00000181921.1
RIKEN cDNA B230217O12 gene
chr11_+_115381906 0.60 ENSMUST00000053288.5
cerebellar degeneration-related protein 2-like
chr15_-_91191733 0.58 ENSMUST00000069511.6
ATP-binding cassette, sub-family D (ALD), member 2
chr7_-_134232125 0.58 ENSMUST00000127524.1
a disintegrin and metallopeptidase domain 12 (meltrin alpha)
chr7_-_70366735 0.58 ENSMUST00000089565.5
nuclear receptor subfamily 2, group F, member 2
chr13_+_43370710 0.58 ENSMUST00000066804.4
sirtuin 5
chr17_+_34629533 0.58 ENSMUST00000015620.6
proline-rich transmembrane protein 1
chr15_+_8109313 0.56 ENSMUST00000163765.1
nucleoporin 155
chr2_-_23155864 0.56 ENSMUST00000028119.6
microtubule associated serine/threonine kinase-like
chr10_+_107271827 0.55 ENSMUST00000020057.8
ENSMUST00000105280.3
lin-7 homolog A (C. elegans)
chr17_-_70849644 0.54 ENSMUST00000134654.1
ENSMUST00000172229.1
ENSMUST00000127719.1
TGFB-induced factor homeobox 1
chr3_-_83049797 0.54 ENSMUST00000048246.3
fibrinogen beta chain
chr9_+_65265173 0.53 ENSMUST00000048762.1
cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
chr19_-_46327121 0.53 ENSMUST00000041391.4
ENSMUST00000096029.5
pleckstrin and Sec7 domain containing
chr10_-_19014549 0.53 ENSMUST00000146388.1
tumor necrosis factor, alpha-induced protein 3
chr17_-_35516780 0.51 ENSMUST00000160885.1
ENSMUST00000159009.1
ENSMUST00000161012.1
transcription factor 19
chr1_+_55237177 0.51 ENSMUST00000061334.8
methionine-tRNA synthetase 2 (mitochondrial)
chrX_+_71555918 0.51 ENSMUST00000072699.6
ENSMUST00000114582.2
ENSMUST00000015361.4
ENSMUST00000088874.3
high mobility group box 3
chr13_+_16014457 0.51 ENSMUST00000164993.1
inhibin beta-A
chr13_-_114388057 0.49 ENSMUST00000022286.6
NADH dehydrogenase (ubiquinone) Fe-S protein 4
chr6_-_136875794 0.49 ENSMUST00000032342.1
matrix Gla protein
chr8_+_46010596 0.49 ENSMUST00000110381.2
Lrp2 binding protein
chr17_-_78906899 0.48 ENSMUST00000042683.6
ENSMUST00000169544.1
sulfotransferase family, cytosolic, 6B, member 1
chr2_-_62573905 0.48 ENSMUST00000102732.3
fibroblast activation protein
chr3_-_59130610 0.48 ENSMUST00000065220.6
ENSMUST00000091112.4
purinergic receptor P2Y, G-protein coupled, 14
chr7_+_88278085 0.47 ENSMUST00000032779.5
ENSMUST00000128791.1
cathepsin C
chr14_+_55824795 0.46 ENSMUST00000024179.5
ENSMUST00000172271.1
nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 4
chr14_+_84443553 0.46 ENSMUST00000071370.5
protocadherin 17
chr3_-_61365951 0.46 ENSMUST00000066298.2
RIKEN cDNA B430305J03 gene
chr5_-_103629279 0.46 ENSMUST00000031263.1
solute carrier family 10 (sodium/bile acid cotransporter family), member 6
chr8_-_122460666 0.46 ENSMUST00000006762.5
snail homolog 3 (Drosophila)
chr14_-_54517353 0.45 ENSMUST00000023873.5
protein arginine N-methyltransferase 5
chr1_+_91801453 0.45 ENSMUST00000007949.3
twist basic helix-loop-helix transcription factor 2
chr3_-_51560816 0.45 ENSMUST00000037141.7
SET domain containing (lysine methyltransferase) 7
chr7_+_130577334 0.45 ENSMUST00000059145.7
ENSMUST00000084513.4
transforming, acidic coiled-coil containing protein 2
chr8_-_107403197 0.44 ENSMUST00000003947.8
NAD(P)H dehydrogenase, quinone 1
chr17_-_45592485 0.44 ENSMUST00000166119.1
solute carrier family 29 (nucleoside transporters), member 1
chr18_-_15718046 0.44 ENSMUST00000053017.6
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9
chr19_-_53371766 0.43 ENSMUST00000086887.1
predicted gene 10197
chr10_+_25359798 0.43 ENSMUST00000053748.8
erythrocyte protein band 4.1-like 2
chr8_-_36732897 0.43 ENSMUST00000098826.3
deleted in liver cancer 1
chr12_+_37241633 0.43 ENSMUST00000049874.7
alkylglycerol monooxygenase
chr13_+_30336433 0.43 ENSMUST00000066412.7
angiotensin II receptor, type 1a
chr3_+_138217814 0.42 ENSMUST00000090171.5
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr17_+_35841668 0.42 ENSMUST00000174124.1
mediator of DNA damage checkpoint 1
chr3_-_145649970 0.42 ENSMUST00000029846.3
cysteine rich protein 61
chr18_+_73863672 0.42 ENSMUST00000134847.1
maestro
chr3_+_84952146 0.42 ENSMUST00000029727.7
F-box and WD-40 domain protein 7
chr13_+_91461050 0.42 ENSMUST00000004094.8
ENSMUST00000042122.8
single-stranded DNA binding protein 2
chr17_-_45592569 0.42 ENSMUST00000163492.1
solute carrier family 29 (nucleoside transporters), member 1
chr7_-_134232005 0.42 ENSMUST00000134504.1
a disintegrin and metallopeptidase domain 12 (meltrin alpha)
chr7_-_45830776 0.40 ENSMUST00000107723.2
ENSMUST00000131384.1
glutamate-rich WD repeat containing 1
chr1_+_193301953 0.40 ENSMUST00000016315.9
laminin, beta 3
chr12_-_69582985 0.39 ENSMUST00000058639.9
methyltransferase like 21D
chr17_-_45474839 0.39 ENSMUST00000024731.8
spermatogenesis associated, serine-rich 1
chr2_+_155751117 0.39 ENSMUST00000029140.5
ENSMUST00000132608.1
protein C receptor, endothelial
chr5_-_89457763 0.38 ENSMUST00000049209.8
group specific component
chr11_+_102835849 0.38 ENSMUST00000107073.1
HIG1 domain family, member 1B
chr3_-_82145865 0.37 ENSMUST00000048976.6
guanylate cyclase 1, soluble, alpha 3
chr7_-_30559600 0.37 ENSMUST00000043975.4
ENSMUST00000156241.1
lin-37 homolog (C. elegans)
chr11_+_62077018 0.37 ENSMUST00000092415.5
sperm antigen with calponin homology and coiled-coil domains 1
chr1_+_12718496 0.37 ENSMUST00000088585.3
sulfatase 1
chr2_-_64975762 0.37 ENSMUST00000156765.1
growth factor receptor bound protein 14
chr2_+_84839395 0.37 ENSMUST00000146816.1
ENSMUST00000028469.7
solute carrier family 43, member 1
chr5_+_66676098 0.36 ENSMUST00000031131.9
ubiquitin carboxy-terminal hydrolase L1
chr7_+_100494044 0.36 ENSMUST00000153287.1
uncoupling protein 2 (mitochondrial, proton carrier)
chr18_-_35722330 0.36 ENSMUST00000133064.1
endothelial cell surface expressed chemotaxis and apoptosis regulator
chr7_+_100493795 0.36 ENSMUST00000129324.1
uncoupling protein 2 (mitochondrial, proton carrier)
chr11_+_70018728 0.36 ENSMUST00000018700.6
ENSMUST00000134376.2
discs, large homolog 4 (Drosophila)
chr11_+_43151599 0.35 ENSMUST00000077659.5
ATPase, class V, type 10B
chr8_+_84970068 0.34 ENSMUST00000164807.1
peroxiredoxin 2
chr2_-_12301914 0.34 ENSMUST00000028106.4
integrin alpha 8
chr7_-_27181149 0.33 ENSMUST00000071986.6
ENSMUST00000121848.1
melanoma inhibitory activity
chr7_-_101921175 0.33 ENSMUST00000098236.2
leucine rich repeat containing 51
chr17_-_70851710 0.33 ENSMUST00000166395.2
TGFB-induced factor homeobox 1
chr10_-_111997204 0.32 ENSMUST00000074805.5
GLI pathogenesis-related 1 (glioma)
chr2_-_34913976 0.32 ENSMUST00000028232.3
PHD finger protein 19
chrX_+_134601271 0.32 ENSMUST00000050331.6
ENSMUST00000059297.5
heterogeneous nuclear ribonucleoprotein H2
chr15_+_3270767 0.32 ENSMUST00000082424.4
ENSMUST00000159158.1
ENSMUST00000159216.1
ENSMUST00000160311.1
selenoprotein P, plasma, 1
chr7_+_46847128 0.31 ENSMUST00000005051.4
lactate dehydrogenase A
chr1_-_180193653 0.31 ENSMUST00000159914.1
aarF domain containing kinase 3
chrX_+_134601179 0.31 ENSMUST00000074950.4
ENSMUST00000113203.1
ENSMUST00000113202.1
heterogeneous nuclear ribonucleoprotein H2
chr4_+_130047840 0.31 ENSMUST00000044565.8
ENSMUST00000132251.1
collagen, type XVI, alpha 1
chr4_-_88880201 0.31 ENSMUST00000056014.2
interferon epsilon
chr6_+_17306335 0.31 ENSMUST00000007799.6
ENSMUST00000115456.1
ENSMUST00000115455.2
ENSMUST00000130505.1
caveolin 1, caveolae protein
chr2_+_3114220 0.30 ENSMUST00000072955.5
family with sequence similarity 171, member A1
chr2_+_61711694 0.30 ENSMUST00000028278.7
proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
chr2_-_148443543 0.30 ENSMUST00000099269.3
CD93 antigen
chr1_-_180193475 0.30 ENSMUST00000160482.1
ENSMUST00000170472.1
aarF domain containing kinase 3
chr9_+_64235201 0.29 ENSMUST00000039011.3
ubiquitin carboxyl-terminal esterase L4
chr11_+_63133068 0.29 ENSMUST00000108700.1
peripheral myelin protein 22
chr2_-_119662756 0.29 ENSMUST00000028768.1
ENSMUST00000110801.1
ENSMUST00000110802.1
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 1
chr17_+_8165501 0.29 ENSMUST00000097419.3
ENSMUST00000024636.8
Fgfr1 oncogene partner
chr3_+_96525163 0.29 ENSMUST00000049208.9
hemochromatosis type 2 (juvenile) (human homolog)
chr13_-_97747399 0.29 ENSMUST00000144993.1
RIKEN cDNA 5330416C01 gene
chr1_+_87327008 0.29 ENSMUST00000172794.1
ENSMUST00000164992.2
GRB10 interacting GYF protein 2
chr1_-_106714217 0.29 ENSMUST00000112751.1
B cell leukemia/lymphoma 2
chr8_-_84969740 0.28 ENSMUST00000109736.2
ENSMUST00000140561.1
ribonuclease H2, large subunit
chrX_-_7671341 0.28 ENSMUST00000033486.5
proteolipid protein 2
chr6_+_108660772 0.28 ENSMUST00000163617.1
basic helix-loop-helix family, member e40
chr7_-_30559828 0.28 ENSMUST00000108164.1
lin-37 homolog (C. elegans)
chr10_-_69212996 0.28 ENSMUST00000170048.1
RIKEN cDNA A930033H14 gene
chr11_+_85832551 0.28 ENSMUST00000000095.6
T-box 2
chr17_-_6961156 0.28 ENSMUST00000063683.6
T cell activation GTPase activating protein 1
chr4_-_129578535 0.27 ENSMUST00000052835.8
family with sequence similarity 167, member B
chr16_-_59555752 0.27 ENSMUST00000179383.1
ENSMUST00000044604.8
beta-gamma crystallin domain containing 3
chr9_+_7692086 0.27 ENSMUST00000018767.7
matrix metallopeptidase 7
chr18_+_88971790 0.27 ENSMUST00000023828.7
rotatin
chr6_-_28831747 0.27 ENSMUST00000062304.5
leucine rich repeat containing 4
chr1_+_87327044 0.27 ENSMUST00000173173.1
GRB10 interacting GYF protein 2
chr12_-_86079019 0.27 ENSMUST00000003687.6
transforming growth factor, beta 3
chr4_-_133872304 0.26 ENSMUST00000157067.2
ribosomal protein S6 kinase polypeptide 1
chr18_-_78123324 0.26 ENSMUST00000160292.1
ENSMUST00000091813.5
solute carrier family 14 (urea transporter), member 1
chr17_-_48432723 0.26 ENSMUST00000046549.3
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 2
chr9_+_62677826 0.26 ENSMUST00000034774.8
integrin alpha 11
chr15_-_85131949 0.25 ENSMUST00000023068.6
structural maintenance of chromosomes 1B
chr6_-_12109583 0.25 ENSMUST00000080891.5
predicted gene 6578
chr8_-_82403203 0.25 ENSMUST00000034148.6
interleukin 15
chr1_-_131200089 0.25 ENSMUST00000068564.8
Ras association (RalGDS/AF-6) domain family member 5
chr11_+_85171096 0.25 ENSMUST00000018623.3
RIKEN cDNA 1700125H20 gene
chr11_+_63132569 0.25 ENSMUST00000108701.1
peripheral myelin protein 22
chr9_-_37255403 0.25 ENSMUST00000161114.1
solute carrier family 37 (glycerol-3-phosphate transporter), member 2
chr3_-_75270073 0.24 ENSMUST00000039047.4
serine (or cysteine) peptidase inhibitor, clade I, member 2
chr15_+_90224293 0.24 ENSMUST00000100309.1
asparagine-linked glycosylation 10B (alpha-1,2-glucosyltransferase)
chr4_-_14796052 0.24 ENSMUST00000108276.1
ENSMUST00000023917.1
leucine rich repeat containing 69
chr7_-_70360593 0.24 ENSMUST00000032768.7
nuclear receptor subfamily 2, group F, member 2
chr10_+_21377290 0.24 ENSMUST00000042699.7
ENSMUST00000159163.1
aldehyde dehydrogenase 8 family, member A1
chr10_-_44458687 0.24 ENSMUST00000105490.2
PR domain containing 1, with ZNF domain
chr18_+_23954668 0.24 ENSMUST00000060762.4
zinc finger protein 397
chr7_-_38227975 0.23 ENSMUST00000098513.4
pleckstrin homology domain containing, family F (with FYVE domain) member 1
chr19_+_3282901 0.23 ENSMUST00000025745.3
ENSMUST00000025743.6
mitochondrial ribosomal protein L21
chr14_+_32856756 0.23 ENSMUST00000053175.5
ENSMUST00000100721.2
V-set and transmembrane domain containing 4
chr13_+_44731281 0.23 ENSMUST00000174086.1
jumonji, AT rich interactive domain 2
chr6_-_40544977 0.22 ENSMUST00000089490.2
olfactory receptor 461
chr15_+_58872646 0.22 ENSMUST00000036937.7
tRNA methyltranferase 12
chr12_-_31654767 0.22 ENSMUST00000020977.2
dihydrouridine synthase 4-like (S. cerevisiae)
chr4_-_11965699 0.22 ENSMUST00000108301.1
ENSMUST00000095144.3
ENSMUST00000108302.1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr11_-_79530569 0.22 ENSMUST00000103236.3
ENSMUST00000170799.1
ENSMUST00000170422.2
ecotropic viral integration site 2a
ecotropic viral integration site 2b
chr2_-_130629994 0.22 ENSMUST00000110262.1
ENSMUST00000028761.4
FAST kinase domains 5
U box domain containing 5
chr10_-_62880014 0.22 ENSMUST00000050826.7
tet methylcytosine dioxygenase 1
chr1_-_170110491 0.21 ENSMUST00000027985.2
discoidin domain receptor family, member 2
chr9_+_35423582 0.21 ENSMUST00000154652.1
cell adhesion molecule-related/down-regulated by oncogenes
chr13_+_44731265 0.21 ENSMUST00000173246.1
jumonji, AT rich interactive domain 2
chr11_+_102836296 0.21 ENSMUST00000021302.8
ENSMUST00000107072.1
HIG1 domain family, member 1B
chr9_-_58158498 0.21 ENSMUST00000168864.2
immunoglobulin superfamily containing leucine-rich repeat
chr9_-_54647199 0.21 ENSMUST00000128163.1
acyl-CoA synthetase bubblegum family member 1
chr4_+_99829437 0.21 ENSMUST00000124547.1
ENSMUST00000106994.1
EF-hand calcium binding domain 7
chr13_-_99412816 0.21 ENSMUST00000180808.1
RIKEN cDNA 6430562O15 gene
chr2_-_121235689 0.20 ENSMUST00000142400.1
transformation related protein 53 binding protein 1
chr6_-_136941694 0.20 ENSMUST00000032344.5
Rho, GDP dissociation inhibitor (GDI) beta
chr12_-_85288419 0.20 ENSMUST00000121930.1
acylphosphatase 1, erythrocyte (common) type
chr11_+_96316684 0.20 ENSMUST00000049241.7
homeobox B4
chr9_-_29963112 0.20 ENSMUST00000075069.4
neurotrimin
chr12_-_54862783 0.20 ENSMUST00000078124.7
cofilin 2, muscle
chr3_+_51559973 0.20 ENSMUST00000180404.1
RIKEN cDNA 5031434O11 gene
chr1_-_179517992 0.20 ENSMUST00000128302.1
ENSMUST00000111134.1
SET and MYND domain containing 3
chr13_+_106947104 0.20 ENSMUST00000022203.8
DIM1 dimethyladenosine transferase 1-like (S. cerevisiae)
chr14_+_19751257 0.20 ENSMUST00000022340.3
nidogen 2
chr8_-_46152159 0.20 ENSMUST00000110378.2
sorting nexin 25
chr2_-_25608447 0.19 ENSMUST00000058137.8
RAB, member of RAS oncogene family-like 6
chr1_+_161494649 0.19 ENSMUST00000086084.1
tumor necrosis factor (ligand) superfamily, member 18
chr3_-_148989316 0.19 ENSMUST00000098518.2
latrophilin 2
chr15_-_98534221 0.19 ENSMUST00000116400.2
ENSMUST00000023727.10
KAT8 regulatory NSL complex subunit 2
chr18_-_35627223 0.19 ENSMUST00000025212.5
solute carrier family 23 (nucleobase transporters), member 1
chr6_+_145934113 0.19 ENSMUST00000032383.7
sarcospan
chr8_+_104101625 0.19 ENSMUST00000034339.8
cadherin 5
chr5_+_53590215 0.19 ENSMUST00000037618.6
recombination signal binding protein for immunoglobulin kappa J region
chr14_+_51884982 0.19 ENSMUST00000167984.1
methyltransferase like 17
chr15_-_77928925 0.19 ENSMUST00000109748.2
ENSMUST00000109747.2
ENSMUST00000100486.5
ENSMUST00000005487.5
thioredoxin 2
chr19_-_47138280 0.19 ENSMUST00000140512.1
ENSMUST00000035822.1
calcium homeostasis modulator 2

Network of associatons between targets according to the STRING database.

First level regulatory network of Nfatc3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 5.6 GO:0060523 prostate epithelial cord elongation(GO:0060523)
0.5 1.5 GO:0010710 regulation of collagen catabolic process(GO:0010710) negative regulation of extracellular matrix disassembly(GO:0010716)
0.4 1.1 GO:0045004 DNA replication proofreading(GO:0045004)
0.4 1.1 GO:0010705 meiotic DNA double-strand break processing involved in reciprocal meiotic recombination(GO:0010705)
0.3 0.8 GO:0003275 apoptotic process involved in outflow tract morphogenesis(GO:0003275) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256) response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869)
0.2 2.3 GO:0009158 ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.2 0.6 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228)
0.2 1.1 GO:1904587 response to glycoprotein(GO:1904587)
0.2 0.5 GO:0070429 regulation of granuloma formation(GO:0002631) negative regulation of granuloma formation(GO:0002632) regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) tolerance induction to lipopolysaccharide(GO:0072573)
0.2 0.8 GO:0060849 regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
0.2 2.3 GO:0036315 cellular response to sterol(GO:0036315)
0.2 0.5 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.1 0.4 GO:0002018 renin-angiotensin regulation of aldosterone production(GO:0002018) regulation of renal output by angiotensin(GO:0002019)
0.1 0.5 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 0.4 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.1 0.4 GO:0052564 response to immune response of other organism involved in symbiotic interaction(GO:0052564) response to host immune response(GO:0052572)
0.1 0.4 GO:1903537 meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
0.1 0.9 GO:0015862 uridine transport(GO:0015862)
0.1 0.5 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.1 0.6 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.1 0.4 GO:0006069 ethanol oxidation(GO:0006069)
0.1 0.5 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.1 0.5 GO:0033078 extrathymic T cell differentiation(GO:0033078)
0.1 0.4 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.1 0.3 GO:0007521 muscle cell fate determination(GO:0007521)
0.1 0.5 GO:0043985 histone H4-R3 methylation(GO:0043985) positive regulation of dopamine receptor signaling pathway(GO:0060161)
0.1 0.6 GO:1904628 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.1 0.3 GO:0003032 detection of oxygen(GO:0003032)
0.1 0.7 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
0.1 0.3 GO:0071918 urea transmembrane transport(GO:0071918)
0.1 0.3 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.1 0.3 GO:2000721 positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.1 0.4 GO:1900085 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
0.1 0.4 GO:0003278 apoptotic process involved in heart morphogenesis(GO:0003278)
0.1 0.4 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.1 0.2 GO:0035481 Notch signaling pathway involved in heart induction(GO:0003137) epidermal cell fate specification(GO:0009957) regulation of Notch signaling pathway involved in heart induction(GO:0035480) positive regulation of Notch signaling pathway involved in heart induction(GO:0035481) arterial endothelial cell fate commitment(GO:0060844) blood vessel endothelial cell fate commitment(GO:0060846) endothelial cell fate specification(GO:0060847) Notch signaling pathway involved in arterial endothelial cell fate commitment(GO:0060853) blood vessel lumenization(GO:0072554) blood vessel endothelial cell fate specification(GO:0097101) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066)
0.1 1.2 GO:0046485 ether lipid metabolic process(GO:0046485)
0.1 0.3 GO:0032847 regulation of nitrogen utilization(GO:0006808) nitrogen utilization(GO:0019740) regulation of cellular pH reduction(GO:0032847)
0.1 0.6 GO:0034372 very-low-density lipoprotein particle remodeling(GO:0034372)
0.1 0.3 GO:0002777 antimicrobial peptide biosynthetic process(GO:0002777) antibacterial peptide biosynthetic process(GO:0002780)
0.1 0.2 GO:2000328 regulation of T-helper 17 cell lineage commitment(GO:2000328)
0.1 0.2 GO:0070904 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.1 0.3 GO:0019244 lactate biosynthetic process from pyruvate(GO:0019244)
0.1 0.4 GO:0007412 axon target recognition(GO:0007412)
0.1 0.5 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.1 0.9 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.1 0.5 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.1 0.6 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.1 0.7 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.1 0.2 GO:0030043 actin filament fragmentation(GO:0030043)
0.1 0.2 GO:0033092 positive regulation of immature T cell proliferation in thymus(GO:0033092)
0.0 0.1 GO:0032765 positive regulation of mast cell cytokine production(GO:0032765)
0.0 0.3 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.0 0.7 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 0.2 GO:0006662 glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904)
0.0 0.3 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.0 0.7 GO:0015809 arginine transport(GO:0015809)
0.0 0.7 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 0.5 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.0 0.2 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0 0.5 GO:0010838 positive regulation of keratinocyte proliferation(GO:0010838)
0.0 0.6 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 0.3 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0 0.6 GO:0010566 regulation of ketone biosynthetic process(GO:0010566)
0.0 0.1 GO:0097309 cap1 mRNA methylation(GO:0097309)
0.0 0.2 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.0 0.1 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
0.0 0.3 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.2 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.0 0.2 GO:1904751 positive regulation of protein localization to nucleolus(GO:1904751)
0.0 0.2 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.2 GO:1901837 negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837)
0.0 0.1 GO:0030202 heparin metabolic process(GO:0030202)
0.0 0.3 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.0 0.5 GO:2000807 regulation of synaptic vesicle clustering(GO:2000807)
0.0 0.3 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.4 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 0.2 GO:0048539 bone marrow development(GO:0048539)
0.0 0.2 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 0.4 GO:0098953 receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628)
0.0 0.1 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 0.2 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.0 0.4 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 0.7 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.0 0.4 GO:0030953 astral microtubule organization(GO:0030953)
0.0 0.1 GO:0090472 dibasic protein processing(GO:0090472)
0.0 0.5 GO:0032060 bleb assembly(GO:0032060)
0.0 0.2 GO:0001955 blood vessel maturation(GO:0001955) positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.0 0.2 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.0 0.2 GO:0051095 regulation of helicase activity(GO:0051095) positive regulation of helicase activity(GO:0051096)
0.0 0.1 GO:0010749 regulation of nitric oxide mediated signal transduction(GO:0010749)
0.0 0.2 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.0 0.2 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.4 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.1 GO:0060689 cell differentiation involved in salivary gland development(GO:0060689)
0.0 0.2 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.1 GO:0009181 purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
0.0 0.4 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.0 0.3 GO:0097119 postsynaptic density protein 95 clustering(GO:0097119)
0.0 0.2 GO:0000963 mitochondrial RNA processing(GO:0000963)
0.0 0.2 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.4 GO:0042359 vitamin D metabolic process(GO:0042359)
0.0 0.5 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.0 0.1 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.0 0.2 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.1 GO:1903936 response to diamide(GO:0072737) cellular response to diamide(GO:0072738) cellular response to sodium arsenite(GO:1903936)
0.0 0.1 GO:0009838 abscission(GO:0009838)
0.0 0.5 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.2 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 0.3 GO:0016540 protein autoprocessing(GO:0016540)
0.0 0.3 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.1 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.1 GO:2000259 positive regulation of complement activation(GO:0045917) progesterone receptor signaling pathway(GO:0050847) positive regulation of protein activation cascade(GO:2000259)
0.0 0.1 GO:0048102 autophagic cell death(GO:0048102)
0.0 0.2 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.1 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.2 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.0 0.0 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.2 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.3 GO:0038065 collagen-activated signaling pathway(GO:0038065)
0.0 0.0 GO:0009804 coumarin metabolic process(GO:0009804)
0.0 0.3 GO:0071549 cellular response to dexamethasone stimulus(GO:0071549)
0.0 0.1 GO:0045409 negative regulation of interleukin-6 biosynthetic process(GO:0045409)
0.0 0.1 GO:2000828 post-embryonic body morphogenesis(GO:0040032) regulation of parathyroid hormone secretion(GO:2000828)
0.0 0.0 GO:2000402 negative regulation of lymphocyte migration(GO:2000402)
0.0 0.3 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.5 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.1 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.0 0.3 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 0.2 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.0 0.0 GO:1903976 negative regulation of glial cell migration(GO:1903976)
0.0 0.5 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.0 0.3 GO:0033622 integrin activation(GO:0033622)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 5.6 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.2 1.1 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.2 1.5 GO:0071438 invadopodium membrane(GO:0071438)
0.2 0.5 GO:0043512 inhibin A complex(GO:0043512)
0.1 1.6 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.1 1.1 GO:0000801 central element(GO:0000801)
0.1 0.6 GO:0044611 nuclear pore inner ring(GO:0044611)
0.1 0.4 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.1 0.7 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.1 0.4 GO:0005610 laminin-5 complex(GO:0005610)
0.1 0.6 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.1 0.8 GO:0031080 nuclear pore outer ring(GO:0031080)
0.1 0.5 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.2 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.3 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 0.2 GO:0032021 NELF complex(GO:0032021)
0.0 0.5 GO:0034709 methylosome(GO:0034709)
0.0 0.7 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.3 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.0 0.3 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.4 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.1 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.3 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.8 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.3 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.5 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.6 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 1.1 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.3 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.1 GO:0031417 NatC complex(GO:0031417)
0.0 0.2 GO:0032300 mismatch repair complex(GO:0032300)
0.0 0.2 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.4 GO:0043218 compact myelin(GO:0043218)
0.0 0.7 GO:0043034 costamere(GO:0043034)
0.0 0.4 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.1 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 2.5 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.1 GO:0008623 CHRAC(GO:0008623)
0.0 0.3 GO:0046930 pore complex(GO:0046930)
0.0 0.2 GO:0031011 Ino80 complex(GO:0031011)
0.0 0.1 GO:0031983 vesicle lumen(GO:0031983)
0.0 0.7 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.5 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.7 GO:0005758 mitochondrial intermembrane space(GO:0005758)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 5.6 GO:0038052 type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.4 1.2 GO:0050479 glyceryl-ether monooxygenase activity(GO:0050479)
0.4 1.8 GO:0008142 oxysterol binding(GO:0008142)
0.2 0.6 GO:0098770 FBXO family protein binding(GO:0098770)
0.2 0.7 GO:0004096 catalase activity(GO:0004096)
0.1 0.7 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768)
0.1 0.4 GO:0004945 angiotensin type II receptor activity(GO:0004945)
0.1 0.4 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.1 1.1 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.1 0.4 GO:1902271 D3 vitamins binding(GO:1902271)
0.1 1.5 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.1 0.7 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.1 2.3 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 0.7 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.1 0.5 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.1 0.6 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.1 0.4 GO:0061513 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.1 0.6 GO:0097016 L27 domain binding(GO:0097016)
0.1 0.7 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.1 0.4 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.1 0.4 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.1 0.4 GO:0001537 N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
0.1 0.3 GO:0004145 diamine N-acetyltransferase activity(GO:0004145)
0.1 0.4 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.1 0.4 GO:0050816 phosphothreonine binding(GO:0050816)
0.1 0.3 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.1 0.7 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 0.2 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.1 0.4 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 0.5 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 0.4 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.1 0.8 GO:0008301 DNA binding, bending(GO:0008301)
0.1 0.2 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179) rRNA (adenine-N6-)-methyltransferase activity(GO:0008988)
0.1 0.3 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 0.5 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.1 0.2 GO:0008520 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.1 0.2 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.1 0.8 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.1 0.2 GO:0003963 RNA-3'-phosphate cyclase activity(GO:0003963)
0.1 0.2 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.1 0.2 GO:1990955 G-rich single-stranded DNA binding(GO:1990955)
0.1 0.2 GO:0032137 guanine/thymine mispair binding(GO:0032137) single guanine insertion binding(GO:0032142)
0.1 0.5 GO:0031404 chloride ion binding(GO:0031404)
0.1 0.2 GO:0003998 acylphosphatase activity(GO:0003998)
0.1 0.3 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 0.4 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.0 2.3 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.3 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.3 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.4 GO:0043996 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 0.2 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.6 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.2 GO:0015265 urea channel activity(GO:0015265)
0.0 0.3 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.2 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.3 GO:0043426 MRF binding(GO:0043426)
0.0 0.1 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0 0.6 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.3 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.2 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 0.5 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.1 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 0.9 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.3 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.4 GO:0017166 vinculin binding(GO:0017166)
0.0 0.1 GO:0086038 calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086038)
0.0 0.9 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.4 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.3 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.7 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.1 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.0 0.8 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.3 GO:0098821 BMP receptor activity(GO:0098821)
0.0 0.2 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.2 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 0.4 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.3 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.2 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 0.5 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.6 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.2 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.1 GO:0016649 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.0 0.1 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.0 0.2 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.1 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.0 0.2 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.5 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.2 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.1 GO:0043262 adenosine-diphosphatase activity(GO:0043262)
0.0 0.2 GO:0046527 glucosyltransferase activity(GO:0046527)
0.0 0.1 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.0 0.3 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.3 GO:0019956 chemokine binding(GO:0019956)
0.0 0.7 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.6 GO:0008146 sulfotransferase activity(GO:0008146)
0.0 0.0 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.1 GO:0051430 corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.0 0.3 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.5 GO:0004812 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.4 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 1.3 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 3.0 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.4 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.1 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 1.2 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.4 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 1.6 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 0.3 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.7 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 2.0 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.5 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.4 PID MYC PATHWAY C-MYC pathway
0.0 0.7 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.5 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.7 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.5 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.0 0.5 PID ATM PATHWAY ATM pathway
0.0 1.0 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.3 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 0.6 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.5 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.2 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 0.2 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.4 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.2 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.3 NABA COLLAGENS Genes encoding collagen proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.1 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.2 2.3 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.1 0.5 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 1.1 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.1 6.1 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 0.3 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.5 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 1.4 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 0.7 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 1.6 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.5 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.5 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.5 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.6 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.5 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 0.7 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.9 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.5 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.4 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.9 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.4 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.4 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.5 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.8 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.9 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.3 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.6 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.4 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.5 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.4 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.1 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.2 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.3 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 1.2 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0 0.3 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.7 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.1 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.3 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.3 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.3 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.2 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling