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12D miR HR13_24

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Results for Hoxb4

Z-value: 0.55

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Transcription factors associated with Hoxb4

Gene Symbol Gene ID Gene Info
ENSMUSG00000038692.7 homeobox B4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hoxb4mm10_v2_chr11_+_96316684_96316684-0.313.5e-01Click!

Activity profile of Hoxb4 motif

Sorted Z-values of Hoxb4 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_+_131032061 0.86 ENSMUST00000084509.3
deleted in malignant brain tumors 1
chr3_-_20275659 0.75 ENSMUST00000011607.5
carboxypeptidase B1 (tissue)
chr11_-_40755201 0.72 ENSMUST00000020576.7
cyclin G1
chr11_-_58529984 0.64 ENSMUST00000062869.2
olfactory receptor 330
chrX_-_143933204 0.50 ENSMUST00000112851.1
ENSMUST00000112856.2
ENSMUST00000033642.3
doublecortin
chr8_-_62123106 0.48 ENSMUST00000034052.6
ENSMUST00000034054.7
annexin A10
chr14_+_58070547 0.48 ENSMUST00000165526.1
fibroblast growth factor 9
chr19_+_4711153 0.44 ENSMUST00000008991.6
spectrin beta, non-erythrocytic 2
chrX_-_143933089 0.41 ENSMUST00000087313.3
doublecortin
chr12_+_58211772 0.41 ENSMUST00000110671.2
ENSMUST00000044299.2
somatostatin receptor 1
chr6_+_116650674 0.30 ENSMUST00000067354.5
ENSMUST00000178241.1
RIKEN cDNA 8430408G22 gene
chr12_-_15816762 0.30 ENSMUST00000020922.7
tribbles homolog 2 (Drosophila)
chr11_+_58580837 0.28 ENSMUST00000169428.2
olfactory receptor 325
chr5_+_143363890 0.27 ENSMUST00000010969.8
glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein 1
chr17_+_86963279 0.27 ENSMUST00000139344.1
ras homolog gene family, member Q
chrX_-_49797700 0.26 ENSMUST00000033442.7
ENSMUST00000114891.1
immunoglobulin superfamily, member 1
chr7_+_30232310 0.21 ENSMUST00000108193.1
ENSMUST00000108192.1
polymerase (RNA) II (DNA directed) polypeptide I
chr18_-_15063560 0.20 ENSMUST00000168989.1
potassium channel tetramerisation domain containing 1
chr2_-_84775420 0.20 ENSMUST00000111641.1
serine (or cysteine) peptidase inhibitor, clade G, member 1
chr11_+_85353156 0.19 ENSMUST00000108061.1
ENSMUST00000108062.1
ENSMUST00000108056.1
ENSMUST00000138423.1
ENSMUST00000074875.4
ENSMUST00000092821.3
breast carcinoma amplified sequence 3
chr10_-_41709297 0.19 ENSMUST00000019955.9
ENSMUST00000099932.3
coiled-coil domain containing 162
chr14_+_27000362 0.19 ENSMUST00000035433.8
homeobox gene expressed in ES cells
chr4_+_99656299 0.19 ENSMUST00000087285.3
forkhead box D3
chr15_-_50889691 0.18 ENSMUST00000165201.2
ENSMUST00000184458.1
trichorhinophalangeal syndrome I (human)
chr2_-_84775388 0.17 ENSMUST00000023994.3
serine (or cysteine) peptidase inhibitor, clade G, member 1
chr2_+_86007778 0.15 ENSMUST00000062166.1
olfactory receptor 1032
chr7_+_28693032 0.14 ENSMUST00000151227.1
ENSMUST00000108281.1
F-box protein 27
chr11_+_46810792 0.14 ENSMUST00000068877.6
T cell immunoglobulin and mucin domain containing 4
chr1_-_171222435 0.13 ENSMUST00000147246.1
ENSMUST00000111326.1
ENSMUST00000138184.1
translocase of outer mitochondrial membrane 40 homolog-like (yeast)
chr7_+_30232032 0.12 ENSMUST00000149654.1
polymerase (RNA) II (DNA directed) polypeptide I
chr17_+_25951472 0.12 ENSMUST00000181174.1
RIKEN cDNA gene D630044L22 gene
chr7_-_30232186 0.11 ENSMUST00000006254.5
tubulin folding cofactor B
chr17_+_43952999 0.11 ENSMUST00000177857.1
regulator of calcineurin 2
chr7_+_30231884 0.09 ENSMUST00000019882.9
polymerase (RNA) II (DNA directed) polypeptide I
chr4_+_58285930 0.09 ENSMUST00000081919.5
ENSMUST00000102893.3
ENSMUST00000084578.5
ENSMUST00000098057.3
ENSMUST00000179951.1
ENSMUST00000098059.3
ENSMUST00000177951.1
muscle, skeletal, receptor tyrosine kinase
chr6_+_142413441 0.09 ENSMUST00000088263.4
RIKEN cDNA B230216G23 gene
chr1_-_171222508 0.08 ENSMUST00000005817.2
translocase of outer mitochondrial membrane 40 homolog-like (yeast)
chr1_-_136006342 0.08 ENSMUST00000166193.2
immunoglobulin-like and fibronectin type III domain containing 1
chr4_-_35845204 0.08 ENSMUST00000164772.1
ENSMUST00000065173.2
leucine rich repeat and Ig domain containing 2
chr8_+_83666827 0.08 ENSMUST00000019608.5
prostaglandin E receptor 1 (subtype EP1)
chr1_+_10993452 0.07 ENSMUST00000027056.5
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
chr8_+_25808474 0.05 ENSMUST00000033979.4
steroidogenic acute regulatory protein
chr1_+_146497614 0.04 ENSMUST00000132847.1
ENSMUST00000166814.1
bone morphogenetic protein/retinoic acid inducible neural specific 3
chr18_-_56562187 0.03 ENSMUST00000171844.2
aldehyde dehydrogenase family 7, member A1
chr2_-_119156824 0.03 ENSMUST00000135419.1
ENSMUST00000129351.1
ENSMUST00000139519.1
ENSMUST00000094695.5
regulator of microtubule dynamics 3
chr10_-_59616667 0.03 ENSMUST00000020312.6
mitochondrial calcium uniporter
chr3_-_30509462 0.03 ENSMUST00000173899.1
MDS1 and EVI1 complex locus
chr16_-_94370450 0.02 ENSMUST00000138514.1
phosphatidylinositol glycan anchor biosynthesis, class P
chr18_-_56562261 0.02 ENSMUST00000066208.6
ENSMUST00000172734.1
aldehyde dehydrogenase family 7, member A1
chr1_+_9545397 0.01 ENSMUST00000072079.7
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
chr17_+_57279094 0.00 ENSMUST00000169220.2
ENSMUST00000005889.9
ENSMUST00000112870.4
vav 1 oncogene

Network of associatons between targets according to the STRING database.

First level regulatory network of Hoxb4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0001192 maintenance of transcriptional fidelity during DNA-templated transcription elongation(GO:0001192) maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter(GO:0001193)
0.1 0.4 GO:0001869 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
0.1 0.3 GO:0042091 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.1 0.9 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.9 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.7 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.2 GO:0030916 otic vesicle formation(GO:0030916)
0.0 0.5 GO:0060484 lung-associated mesenchyme development(GO:0060484)
0.0 0.1 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.0 0.4 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.0 0.4 GO:0021692 cerebellar Purkinje cell layer morphogenesis(GO:0021692)
0.0 0.2 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.1 GO:1904253 positive regulation of bile acid biosynthetic process(GO:0070859) positive regulation of bile acid metabolic process(GO:1904253)
0.0 0.3 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 0.2 GO:0071391 cellular response to estrogen stimulus(GO:0071391)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.1 0.4 GO:0008091 spectrin(GO:0008091)
0.0 0.2 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.4 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0004994 somatostatin receptor activity(GO:0004994)
0.1 0.2 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.0 0.2 GO:0015288 porin activity(GO:0015288)
0.0 0.3 GO:0034711 inhibin binding(GO:0034711)
0.0 0.7 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.3 GO:0005522 profilin binding(GO:0005522)
0.0 0.1 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.9 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 1.1 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.3 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.4 GO:0001848 complement binding(GO:0001848)
0.0 0.5 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.1 GO:0004957 prostaglandin E receptor activity(GO:0004957)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.4 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.4 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.4 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins