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12D miR HR13_24

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Results for Bcl6

Z-value: 1.47

Motif logo

Transcription factors associated with Bcl6

Gene Symbol Gene ID Gene Info
ENSMUSG00000022508.5 B cell leukemia/lymphoma 6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Bcl6mm10_v2_chr16_-_23988852_23988852-0.643.2e-02Click!

Activity profile of Bcl6 motif

Sorted Z-values of Bcl6 motif

Promoter Log-likelihood Transcript Gene Gene Info
chrX_+_164436987 4.57 ENSMUST00000036858.4
ankyrin repeat and SOCS box-containing 11
chr4_+_120666562 3.24 ENSMUST00000094814.4
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4
chr11_+_120530688 3.19 ENSMUST00000026119.7
glucagon receptor
chr2_+_70563435 3.06 ENSMUST00000123330.1
glutamate decarboxylase 1
chr2_+_70562854 2.78 ENSMUST00000130998.1
glutamate decarboxylase 1
chr9_-_121792478 2.67 ENSMUST00000035110.4
hedgehog acyltransferase-like
chr6_-_5496296 2.34 ENSMUST00000019721.4
pyruvate dehydrogenase kinase, isoenzyme 4
chr2_-_80447625 2.23 ENSMUST00000028389.3
frizzled-related protein
chr1_-_169747634 2.17 ENSMUST00000027991.5
ENSMUST00000111357.1
regulator of G-protein signaling 4
chr6_+_43265582 2.14 ENSMUST00000031750.7
Rho guanine nucleotide exchange factor (GEF) 5
chr9_+_107296843 2.02 ENSMUST00000167072.1
cytokine inducible SH2-containing protein
chr4_+_115088708 1.96 ENSMUST00000171877.1
ENSMUST00000177647.1
ENSMUST00000106548.2
ENSMUST00000030488.2
PDZK1 interacting protein 1
chr3_+_89418443 1.96 ENSMUST00000039110.5
ENSMUST00000125036.1
ENSMUST00000154791.1
ENSMUST00000128238.1
ENSMUST00000107417.2
src homology 2 domain-containing transforming protein C1
chr9_+_107296682 1.94 ENSMUST00000168260.1
cytokine inducible SH2-containing protein
chr16_-_21787796 1.89 ENSMUST00000023559.5
enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase
chr8_+_68880491 1.62 ENSMUST00000015712.8
lipoprotein lipase
chr3_-_89093358 1.56 ENSMUST00000090929.5
ENSMUST00000052539.6
RUN and SH3 domain containing 1
chr5_-_123865491 1.56 ENSMUST00000057145.5
niacin receptor 1
chr18_-_32139570 1.53 ENSMUST00000171765.1
protein C
chr18_+_50053282 1.44 ENSMUST00000148159.2
tumor necrosis factor, alpha-induced protein 8
chrX_+_164140447 1.39 ENSMUST00000073973.4
angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
chr7_-_30924169 1.30 ENSMUST00000074671.6
hepcidin antimicrobial peptide 2
chr7_+_104244449 1.30 ENSMUST00000106849.2
ENSMUST00000060315.5
tripartite motif-containing 34A
chr12_-_103631404 1.28 ENSMUST00000121625.1
ENSMUST00000044231.5
serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
chr6_+_97929799 1.25 ENSMUST00000101123.3
microphthalmia-associated transcription factor
chr7_+_104244465 1.23 ENSMUST00000106848.1
tripartite motif-containing 34A
chr19_+_46152505 1.20 ENSMUST00000026254.7
golgi-specific brefeldin A-resistance factor 1
chr7_+_104244496 1.19 ENSMUST00000106854.1
ENSMUST00000143414.1
tripartite motif-containing 34A
chr7_-_127930066 1.17 ENSMUST00000032988.8
protease, serine, 8 (prostasin)
chr13_+_23555023 1.15 ENSMUST00000045301.6
histone cluster 1, H1d
chr11_+_93098404 1.11 ENSMUST00000107859.1
ENSMUST00000042943.6
ENSMUST00000107861.1
ENSMUST00000107858.2
carbonic anhydrase 10
chrX_+_153832225 1.09 ENSMUST00000148708.1
ENSMUST00000123264.1
ENSMUST00000049999.8
spindlin family, member 2C
chr14_+_118137101 1.08 ENSMUST00000022728.2
G protein-coupled receptor 180
chr1_+_125676969 1.08 ENSMUST00000027581.6
G protein-coupled receptor 39
chr6_+_41521782 1.08 ENSMUST00000070380.4
protease, serine, 2
chr18_-_3281036 1.07 ENSMUST00000049942.6
ENSMUST00000139537.1
ENSMUST00000124747.1
cAMP responsive element modulator
chr5_+_30466044 1.04 ENSMUST00000031078.3
ENSMUST00000114743.1
RIKEN cDNA 1700001C02 gene
chr4_-_47010781 1.04 ENSMUST00000135777.1
predicted gene 568
chr1_+_134182150 1.01 ENSMUST00000156873.1
chitinase 3-like 1
chr14_-_63245219 1.00 ENSMUST00000118022.1
ENSMUST00000067417.3
GATA binding protein 4
chr9_+_45117813 1.00 ENSMUST00000170998.1
ENSMUST00000093855.3
sodium channel, voltage-gated, type II, beta
chr10_+_95417352 0.99 ENSMUST00000181781.1
RIKEN cDNA 5730420D15 gene
chr10_-_86705485 0.98 ENSMUST00000020238.7
heat shock protein 90, beta (Grp94), member 1
chr6_+_139621888 0.98 ENSMUST00000032353.8
phosphatidylinositol 3-kinase, C2 domain containing, gamma polypeptide
chr5_+_123015010 0.97 ENSMUST00000121652.1
ENSMUST00000051016.4
ORAI calcium release-activated calcium modulator 1
chr14_-_51146757 0.95 ENSMUST00000080126.2
ribonuclease, RNase A family, 1 (pancreatic)
chr18_-_36726730 0.95 ENSMUST00000061829.6
CD14 antigen
chr8_+_106510853 0.94 ENSMUST00000080797.6
cadherin 3
chr9_+_38718263 0.91 ENSMUST00000001544.5
ENSMUST00000118144.1
von Willebrand factor A domain containing 5A
chr10_+_112165676 0.90 ENSMUST00000170013.1
calcyphosphine 2
chr3_-_89365233 0.88 ENSMUST00000070820.6
DC-STAMP domain containing 1
chr2_-_155729359 0.88 ENSMUST00000040833.4
ER degradation enhancer, mannosidase alpha-like 2
chr9_-_95815389 0.84 ENSMUST00000119760.1
plastin 1 (I-isoform)
chr16_-_35871544 0.84 ENSMUST00000042665.8
poly (ADP-ribose) polymerase family, member 14
chr14_-_30607808 0.82 ENSMUST00000112207.1
ENSMUST00000112206.1
ENSMUST00000112202.1
ENSMUST00000112203.1
protein kinase C, delta
chrX_+_101376359 0.81 ENSMUST00000119080.1
gap junction protein, beta 1
chr10_-_95417099 0.77 ENSMUST00000135822.1
suppressor of cytokine signaling 2
chr2_-_63184253 0.76 ENSMUST00000075052.3
ENSMUST00000112454.1
potassium voltage-gated channel, subfamily H (eag-related), member 7
chr8_+_119666498 0.75 ENSMUST00000024107.5
WAP four-disulfide core domain 1
chr5_-_6876523 0.75 ENSMUST00000164784.1
zinc finger protein 804B
chr9_-_100571049 0.74 ENSMUST00000093792.2
solute carrier family 35, member G2
chr17_+_29135056 0.74 ENSMUST00000087942.4
RAB44, member RAS oncogene family
chr13_-_67399738 0.73 ENSMUST00000181071.1
ENSMUST00000109732.1
zinc finger protein 429
chr4_+_15881255 0.72 ENSMUST00000029876.1
calbindin 1
chr14_-_70627008 0.72 ENSMUST00000110984.2
dematin actin binding protein
chr5_+_90561102 0.72 ENSMUST00000094615.4
RIKEN cDNA 5830473C10 gene
chr10_-_128401218 0.71 ENSMUST00000042666.5
solute carrier family 39 (metal ion transporter), member 5
chr9_+_86743641 0.71 ENSMUST00000179574.1
protease, serine, 35
chr8_+_94532990 0.70 ENSMUST00000048653.2
ENSMUST00000109537.1
copine II
chr11_+_54438188 0.70 ENSMUST00000046835.7
folliculin interacting protein 1
chr6_-_13838432 0.68 ENSMUST00000115492.1
G protein-coupled receptor 85
chr1_-_175491130 0.67 ENSMUST00000027812.5
regulator of G protein signaling 7
chr14_+_33941021 0.64 ENSMUST00000100720.1
growth differentiation factor 2
chr15_+_52295509 0.63 ENSMUST00000037240.2
solute carrier family 30 (zinc transporter), member 8
chr2_+_164948219 0.63 ENSMUST00000017881.2
matrix metallopeptidase 9
chr14_-_21989475 0.61 ENSMUST00000043409.7
zinc finger protein 503
chr14_+_122107119 0.60 ENSMUST00000171318.1
transmembrane 9 superfamily member 2
chr14_-_54253907 0.60 ENSMUST00000128231.1
defender against cell death 1
chr7_-_126898249 0.59 ENSMUST00000121532.1
ENSMUST00000032926.5
transmembrane protein 219
chr10_-_95416850 0.59 ENSMUST00000020215.9
suppressor of cytokine signaling 2
chr17_-_57247632 0.59 ENSMUST00000005975.6
G protein-coupled receptor 108
chr4_+_62559825 0.58 ENSMUST00000065870.7
regulator of G-protein signaling 3
chr12_-_12941827 0.57 ENSMUST00000043396.7
v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)
chr5_-_135573036 0.57 ENSMUST00000004936.6
chemokine (C-C motif) ligand 24
chr11_+_87699897 0.57 ENSMUST00000040089.4
ring finger protein 43
chr19_+_46341118 0.56 ENSMUST00000128041.1
transmembrane protein 180
chr10_-_18023229 0.55 ENSMUST00000020002.7
ABRA C-terminal like
chr9_+_77941274 0.55 ENSMUST00000134072.1
ELOVL family member 5, elongation of long chain fatty acids (yeast)
chr7_-_126897424 0.54 ENSMUST00000120007.1
transmembrane protein 219
chr9_-_39604124 0.53 ENSMUST00000042485.4
ENSMUST00000141370.1
expressed sequence AW551984
chr10_+_87521920 0.53 ENSMUST00000142088.1
phenylalanine hydroxylase
chr12_+_28675220 0.53 ENSMUST00000020957.6
acireductone dioxygenase 1
chr7_-_30944017 0.53 ENSMUST00000062620.7
hepcidin antimicrobial peptide
chr5_-_137116177 0.53 ENSMUST00000054384.5
ENSMUST00000152207.1
tripartite motif-containing 56
chr15_-_54920115 0.53 ENSMUST00000171545.1
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr10_+_86300372 0.51 ENSMUST00000020234.7
tissue inhibitor of metalloproteinase 3
chr7_-_80232556 0.51 ENSMUST00000071457.5
calcium and integrin binding 1 (calmyrin)
chr7_-_126463100 0.51 ENSMUST00000032974.6
ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
chr7_-_80232752 0.50 ENSMUST00000065163.8
calcium and integrin binding 1 (calmyrin)
chr18_+_37484955 0.50 ENSMUST00000053856.4
protocadherin beta 17
chr7_-_142661305 0.49 ENSMUST00000105936.1
insulin-like growth factor 2
chr11_+_103133333 0.49 ENSMUST00000124928.1
ENSMUST00000062530.4
hexamethylene bis-acetamide inducible 2
chr9_+_86743616 0.49 ENSMUST00000036426.6
protease, serine, 35
chrX_-_73930834 0.48 ENSMUST00000116578.1
renin binding protein
chr7_-_80232479 0.48 ENSMUST00000123279.1
calcium and integrin binding 1 (calmyrin)
chr15_-_79141197 0.48 ENSMUST00000169604.1
RIKEN cDNA 1700088E04 gene
chr10_+_99443699 0.47 ENSMUST00000167243.1
glutamate decarboxylase 1, pseudogene
chr10_-_128821576 0.47 ENSMUST00000026409.3
ORM1-like 2 (S. cerevisiae)
chr19_-_43986552 0.47 ENSMUST00000026210.4
carboxypeptidase N, polypeptide 1
chr1_+_169928648 0.47 ENSMUST00000094348.3
RIKEN cDNA 1700084C01 gene
chr7_+_43995833 0.47 ENSMUST00000007156.4
kallikrein 1-related peptidase b11
chr5_+_86071734 0.45 ENSMUST00000031171.7
signal transducing adaptor family member 1
chr3_+_142530329 0.45 ENSMUST00000171263.1
ENSMUST00000045097.9
guanylate binding protein 7
chr9_-_107541816 0.44 ENSMUST00000041459.3
cytochrome b-561 domain containing 2
chr7_+_66839752 0.44 ENSMUST00000107478.1
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 17
chr8_-_67910911 0.44 ENSMUST00000093468.5
pleckstrin and Sec7 domain containing 3
chr3_+_10366903 0.43 ENSMUST00000029049.5
charged multivesicular body protein 4C
chr11_+_66911981 0.43 ENSMUST00000123434.2
phosphoinositide-interacting regulator of transient receptor potential channels
chr2_-_132578244 0.42 ENSMUST00000110142.1
glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)
chr6_+_83711232 0.41 ENSMUST00000037807.1
ventral anterior homeobox containing gene 2
chr3_-_146685592 0.41 ENSMUST00000125965.1
sterile alpha motif domain containing 13
chr13_-_67755132 0.41 ENSMUST00000091520.6
zinc finger protein 85, related sequence 1
chr3_+_63295815 0.40 ENSMUST00000029400.1
membrane metallo endopeptidase
chr8_+_105827721 0.40 ENSMUST00000034365.4
translin-associated factor X (Tsnax) interacting protein 1
chr5_+_67260794 0.40 ENSMUST00000161369.1
transmembrane protein 33
chr4_-_32602760 0.39 ENSMUST00000056517.2
gap junction protein, alpha 10
chrX_-_73930751 0.39 ENSMUST00000155597.1
ENSMUST00000114379.1
renin binding protein
chr17_-_56982120 0.38 ENSMUST00000056113.4
alkaline ceramidase 1
chr19_-_10556198 0.38 ENSMUST00000025569.2
transmembrane protein 216
chr13_-_67755192 0.38 ENSMUST00000144183.1
zinc finger protein 85, related sequence 1
chr7_+_66839726 0.38 ENSMUST00000098382.3
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 17
chr13_-_23698454 0.37 ENSMUST00000102967.1
histone cluster 1, H4c
chr4_-_64046925 0.37 ENSMUST00000107377.3
tenascin C
chr8_+_111033890 0.36 ENSMUST00000034441.7
alanyl-tRNA synthetase
chr11_+_103133303 0.36 ENSMUST00000107037.1
hexamethylene bis-acetamide inducible 2
chr11_-_48871344 0.36 ENSMUST00000049519.3
immunity-related GTPase family M member 1
chr1_+_191717834 0.36 ENSMUST00000110855.1
ENSMUST00000133076.1
lysophosphatidylglycerol acyltransferase 1
chr11_+_51763682 0.36 ENSMUST00000020653.5
SAR1 gene homolog B (S. cerevisiae)
chr8_-_18741542 0.36 ENSMUST00000033846.6
angiopoietin 2
chr3_+_37348645 0.35 ENSMUST00000038885.3
fibroblast growth factor 2
chr10_+_87521954 0.35 ENSMUST00000143624.1
phenylalanine hydroxylase
chr10_+_87521795 0.35 ENSMUST00000020241.8
phenylalanine hydroxylase
chr11_-_59228162 0.35 ENSMUST00000163300.1
ENSMUST00000061242.7
ADP-ribosylation factor 1
chr17_-_32886083 0.35 ENSMUST00000178401.1
zinc finger protein 870
chr9_+_44981779 0.35 ENSMUST00000034602.7
CD3 antigen, delta polypeptide
chr15_-_54919961 0.34 ENSMUST00000167541.2
ENSMUST00000041591.9
ENSMUST00000173516.1
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr10_+_78055327 0.34 ENSMUST00000131825.1
ENSMUST00000139539.1
ENSMUST00000123940.1
DNA (cytosine-5-)-methyltransferase 3-like
chr13_+_21722057 0.34 ENSMUST00000110476.3
histone cluster 1, H2bm
chr11_-_101175440 0.33 ENSMUST00000062759.3
chemokine (C-C motif) receptor 10
chr2_+_154656959 0.33 ENSMUST00000044277.9
charged multivesicular body protein 4B
chr5_-_38480131 0.32 ENSMUST00000143758.1
ENSMUST00000067886.5
solute carrier family 2 (facilitated glucose transporter), member 9
chr5_+_122284365 0.32 ENSMUST00000053426.8
PTC7 protein phosphatase homolog (S. cerevisiae)
chr4_-_135272798 0.32 ENSMUST00000037099.8
chloride intracellular channel 4 (mitochondrial)
chr6_-_12109583 0.32 ENSMUST00000080891.5
predicted gene 6578
chr6_+_48448100 0.31 ENSMUST00000169350.2
ENSMUST00000043676.5
SCO-spondin
chr15_+_73512559 0.31 ENSMUST00000043414.5
DENN/MADD domain containing 3
chr9_+_50752758 0.31 ENSMUST00000034562.7
crystallin, alpha B
chrX_-_106840572 0.31 ENSMUST00000062010.9
zinc finger, CCHC domain containing 5
chr14_-_55524191 0.30 ENSMUST00000111404.1
neural retina leucine zipper gene
chr11_-_118401826 0.29 ENSMUST00000106290.3
ENSMUST00000043722.3
lectin, galactoside-binding, soluble, 3 binding protein
chr8_+_71887264 0.29 ENSMUST00000034259.7
zinc finger protein 709
chr16_-_90934506 0.29 ENSMUST00000142340.1
RIKEN cDNA 1110004E09 gene
chr1_-_153808163 0.28 ENSMUST00000141249.1
regulator of G-protein signaling like 1
chr5_+_67260565 0.28 ENSMUST00000037918.5
ENSMUST00000162543.1
transmembrane protein 33
chr8_+_84901928 0.27 ENSMUST00000067060.7
Kruppel-like factor 1 (erythroid)
chr3_+_96576984 0.27 ENSMUST00000148290.1
predicted gene 16253
chr7_+_25077205 0.26 ENSMUST00000179556.1
ENSMUST00000053410.9
zinc finger protein 574
chr4_+_144892813 0.25 ENSMUST00000105744.1
ENSMUST00000171001.1
dehydrogenase/reductase (SDR family) member 3
chr18_+_46925982 0.25 ENSMUST00000097580.1
ADP-ribosylation factor-like 14 effector protein-like
chr7_+_45514581 0.25 ENSMUST00000151506.1
ENSMUST00000085331.5
ENSMUST00000126061.1
tubby-like protein 2
chr10_+_29143996 0.25 ENSMUST00000092629.2
SOGA family member 3
chr3_-_86002491 0.24 ENSMUST00000061343.3
protease, serine, 48
chr8_-_104624266 0.24 ENSMUST00000163783.2
cadherin 16
chr12_+_69372112 0.24 ENSMUST00000050063.7
ADP-ribosylation factor 6
chr15_-_8710409 0.24 ENSMUST00000157065.1
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr11_-_48871408 0.23 ENSMUST00000097271.2
immunity-related GTPase family M member 1
chr8_-_111337793 0.23 ENSMUST00000145862.1
mixed lineage kinase domain-like
chr14_-_37048957 0.23 ENSMUST00000022338.5
retinal G protein coupled receptor
chr16_-_5222257 0.23 ENSMUST00000050160.4
expressed sequence AU021092
chr15_-_5108492 0.23 ENSMUST00000118365.2
caspase recruitment domain family, member 6
chr17_+_23853519 0.22 ENSMUST00000061725.7
protease, serine, 32
chr11_-_75190458 0.22 ENSMUST00000044949.4
DPH1 homolog (S. cerevisiae)
chr9_+_80067452 0.22 ENSMUST00000165607.2
SUMO/sentrin specific peptidase 6
chr5_+_67260696 0.21 ENSMUST00000161233.1
ENSMUST00000160352.1
transmembrane protein 33
chr9_-_35267746 0.21 ENSMUST00000125087.1
ENSMUST00000121564.1
ENSMUST00000063782.5
ENSMUST00000059057.7
family with sequence similarity 118, member B
chr13_-_23369156 0.20 ENSMUST00000125328.1
ENSMUST00000145451.1
ENSMUST00000050101.2
zinc finger protein 322A
chr14_+_28504736 0.20 ENSMUST00000063465.4
wingless-related MMTV integration site 5A
chr8_-_105991741 0.20 ENSMUST00000117555.1
ENSMUST00000034373.7
dipeptidase 2
chr14_+_26693267 0.20 ENSMUST00000022433.4
dynein, axonemal, heavy chain 12
chr2_+_101886249 0.20 ENSMUST00000028584.7
COMM domain containing 9
chr5_-_140702241 0.19 ENSMUST00000077890.5
ENSMUST00000041783.7
ENSMUST00000142081.1
IQ motif containing E
chr17_-_47688028 0.19 ENSMUST00000113301.1
ENSMUST00000113302.3
translocase of outer mitochondrial membrane 6 homolog (yeast)
chrX_-_10216918 0.19 ENSMUST00000072393.2
ENSMUST00000044598.6
ENSMUST00000073392.4
ENSMUST00000115533.1
ENSMUST00000115532.1
retinitis pigmentosa GTPase regulator
chr4_+_33062999 0.18 ENSMUST00000108162.1
ENSMUST00000024035.2
gamma-aminobutyric acid (GABA) C receptor, subunit rho 2
chr7_+_110768169 0.18 ENSMUST00000170374.1
adenosine monophosphate deaminase 3
chr9_-_50752348 0.18 ENSMUST00000042790.3
heat shock protein 2
chr17_+_74489492 0.18 ENSMUST00000024873.6
Yip1 domain family, member 4
chr15_-_78572754 0.18 ENSMUST00000043214.6
RAS-related C3 botulinum substrate 2
chr7_-_37770757 0.18 ENSMUST00000176680.1
zinc finger protein 536
chr4_+_154856200 0.18 ENSMUST00000050220.2
tetratricopeptide repeat domain 34

Network of associatons between targets according to the STRING database.

First level regulatory network of Bcl6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 6.1 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.6 2.3 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.5 2.1 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
0.5 2.7 GO:1903059 regulation of protein lipidation(GO:1903059)
0.5 3.2 GO:0033762 response to glucagon(GO:0033762)
0.5 1.8 GO:0034757 negative regulation of iron ion transport(GO:0034757) negative regulation of iron ion transmembrane transport(GO:0034760)
0.4 2.2 GO:0070366 regulation of hepatocyte differentiation(GO:0070366)
0.4 0.9 GO:1904154 positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.4 1.2 GO:0006571 tyrosine biosynthetic process(GO:0006571) aromatic amino acid family biosynthetic process(GO:0009073) aromatic amino acid family biosynthetic process, prephenate pathway(GO:0009095)
0.4 1.2 GO:0035964 COPI-coated vesicle budding(GO:0035964) protein localization to endoplasmic reticulum exit site(GO:0070973)
0.4 2.0 GO:1990839 response to endothelin(GO:1990839)
0.4 1.5 GO:2000256 endomitotic cell cycle(GO:0007113) thrombopoietin-mediated signaling pathway(GO:0038163) positive regulation of male germ cell proliferation(GO:2000256)
0.3 1.4 GO:0015827 aromatic amino acid transport(GO:0015801) tryptophan transport(GO:0015827)
0.3 1.0 GO:1905204 septum secundum development(GO:0003285) cardiac muscle tissue regeneration(GO:0061026) negative regulation of connective tissue replacement(GO:1905204)
0.3 1.6 GO:0055096 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096)
0.3 1.0 GO:0071725 response to diacyl bacterial lipopeptide(GO:0071724) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to diacyl bacterial lipopeptide(GO:0071726) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.3 0.9 GO:0051794 regulation of catagen(GO:0051794)
0.3 0.9 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.3 1.1 GO:0035482 gastric motility(GO:0035482)
0.2 0.7 GO:0072221 distal convoluted tubule development(GO:0072025) metanephric distal convoluted tubule development(GO:0072221) metanephric distal tubule development(GO:0072235)
0.2 0.7 GO:0035585 calcium-mediated signaling using extracellular calcium source(GO:0035585)
0.2 0.7 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
0.2 1.5 GO:1903142 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.2 0.8 GO:1902896 terminal web assembly(GO:1902896)
0.2 0.8 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.2 0.8 GO:0006680 glucosylceramide catabolic process(GO:0006680)
0.2 0.6 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
0.2 1.0 GO:0046684 response to pyrethroid(GO:0046684)
0.2 0.6 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.2 0.7 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
0.2 0.5 GO:1903984 positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.2 0.5 GO:0031448 regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448)
0.2 1.1 GO:0016584 nucleosome positioning(GO:0016584)
0.2 0.5 GO:1900060 negative regulation of ceramide biosynthetic process(GO:1900060)
0.2 0.5 GO:1902226 negative regulation of macrophage chemotaxis(GO:0010760) regulation of macrophage colony-stimulating factor signaling pathway(GO:1902226) regulation of response to macrophage colony-stimulating factor(GO:1903969) regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903972)
0.1 0.4 GO:0044878 mitotic cytokinesis checkpoint(GO:0044878)
0.1 0.4 GO:0071492 cellular response to UV-A(GO:0071492)
0.1 0.5 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.1 0.4 GO:0010446 response to alkaline pH(GO:0010446)
0.1 0.6 GO:0019087 transformation of host cell by virus(GO:0019087)
0.1 0.9 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.1 0.9 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.1 0.4 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.1 4.0 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.1 0.5 GO:0030070 insulin processing(GO:0030070)
0.1 0.3 GO:0036090 cleavage furrow ingression(GO:0036090) lysosomal membrane organization(GO:0097212)
0.1 0.3 GO:0045872 positive regulation of rhodopsin gene expression(GO:0045872)
0.1 1.2 GO:0044336 canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
0.1 0.6 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.1 0.4 GO:0014012 peripheral nervous system axon regeneration(GO:0014012) bud outgrowth involved in lung branching(GO:0060447)
0.1 0.4 GO:0060128 corticotropin hormone secreting cell differentiation(GO:0060128)
0.1 0.3 GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.1 0.8 GO:0015868 purine ribonucleotide transport(GO:0015868)
0.1 1.1 GO:0031000 response to caffeine(GO:0031000)
0.1 0.4 GO:0048014 Tie signaling pathway(GO:0048014)
0.1 1.0 GO:0071318 cellular response to ATP(GO:0071318)
0.1 1.2 GO:0070633 transepithelial transport(GO:0070633)
0.1 0.2 GO:0060599 hypophysis morphogenesis(GO:0048850) cervix development(GO:0060067) lateral sprouting involved in mammary gland duct morphogenesis(GO:0060599) planar cell polarity pathway involved in outflow tract morphogenesis(GO:0061347) planar cell polarity pathway involved in ventricular septum morphogenesis(GO:0061348) planar cell polarity pathway involved in cardiac right atrium morphogenesis(GO:0061349) planar cell polarity pathway involved in cardiac muscle tissue morphogenesis(GO:0061350) planar cell polarity pathway involved in pericardium morphogenesis(GO:0061354) regulation of cell proliferation in midbrain(GO:1904933)
0.1 0.6 GO:0060335 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335) positive regulation of autophagosome maturation(GO:1901098)
0.1 0.6 GO:2000980 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.1 0.5 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.1 1.0 GO:0019236 response to pheromone(GO:0019236)
0.1 0.2 GO:0042938 dipeptide transport(GO:0042938)
0.1 0.6 GO:0032119 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.1 0.2 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.1 0.2 GO:0000270 peptidoglycan metabolic process(GO:0000270) natural killer cell differentiation involved in immune response(GO:0002325) peptidoglycan catabolic process(GO:0009253) negative regulation of natural killer cell differentiation(GO:0032824) regulation of natural killer cell differentiation involved in immune response(GO:0032826) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827)
0.1 0.2 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.1 1.4 GO:0060396 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.1 0.6 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.1 0.2 GO:0030576 Cajal body organization(GO:0030576)
0.0 0.7 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 1.0 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.6 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.2 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.3 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.4 GO:0032264 IMP salvage(GO:0032264)
0.0 0.5 GO:0060923 cardiac muscle cell fate commitment(GO:0060923)
0.0 1.0 GO:0039703 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.0 0.5 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.0 0.4 GO:0072502 cellular phosphate ion homeostasis(GO:0030643) cellular divalent inorganic anion homeostasis(GO:0072501) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.1 GO:2000331 regulation of terminal button organization(GO:2000331)
0.0 0.3 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
0.0 0.2 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.0 1.8 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.0 0.3 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.1 GO:0003257 positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation(GO:0003257)
0.0 0.9 GO:1904030 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.0 0.1 GO:0090264 immune complex clearance by monocytes and macrophages(GO:0002436) monocyte homeostasis(GO:0035702) regulation of immune complex clearance by monocytes and macrophages(GO:0090264) positive regulation of immune complex clearance by monocytes and macrophages(GO:0090265)
0.0 0.3 GO:0045059 positive thymic T cell selection(GO:0045059)
0.0 0.2 GO:0060753 regulation of mast cell chemotaxis(GO:0060753)
0.0 0.2 GO:0090527 actin filament reorganization(GO:0090527)
0.0 0.5 GO:0044406 adhesion of symbiont to host(GO:0044406)
0.0 0.5 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.0 0.2 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 2.3 GO:0043627 response to estrogen(GO:0043627)
0.0 0.1 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.2 GO:0015808 L-alanine transport(GO:0015808)
0.0 0.2 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.0 0.2 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.3 GO:0046415 urate metabolic process(GO:0046415)
0.0 0.1 GO:1903028 regulation of opsonization(GO:1903027) positive regulation of opsonization(GO:1903028)
0.0 1.4 GO:0032611 interleukin-1 beta production(GO:0032611)
0.0 0.4 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 1.6 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.0 1.1 GO:0051591 response to cAMP(GO:0051591)
0.0 0.4 GO:0009950 dorsal/ventral axis specification(GO:0009950)
0.0 0.7 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.4 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.2 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.0 0.2 GO:0034143 regulation of toll-like receptor 4 signaling pathway(GO:0034143)
0.0 0.1 GO:0003356 regulation of cilium beat frequency(GO:0003356)
0.0 0.2 GO:0036159 inner dynein arm assembly(GO:0036159)
0.0 1.0 GO:0090501 RNA phosphodiester bond hydrolysis(GO:0090501)
0.0 2.1 GO:0051607 defense response to virus(GO:0051607)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.1 5.4 GO:0060077 inhibitory synapse(GO:0060077)
0.1 0.6 GO:0097447 dendritic tree(GO:0097447)
0.1 1.0 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 0.5 GO:0035339 SPOTS complex(GO:0035339)
0.1 0.8 GO:1990357 terminal web(GO:1990357)
0.1 0.5 GO:0031673 H zone(GO:0031673)
0.1 1.6 GO:0042627 chylomicron(GO:0042627)
0.1 1.0 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 1.5 GO:0032433 filopodium tip(GO:0032433)
0.1 1.0 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.7 GO:0090543 Flemming body(GO:0090543)
0.0 0.7 GO:0044292 dendrite terminus(GO:0044292)
0.0 1.0 GO:0005922 connexon complex(GO:0005922)
0.0 0.1 GO:0044299 C-fiber(GO:0044299)
0.0 0.6 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.6 GO:0044754 autolysosome(GO:0044754)
0.0 0.3 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.5 GO:0020005 symbiont-containing vacuole membrane(GO:0020005)
0.0 0.3 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.9 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.3 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.9 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 1.2 GO:0005801 cis-Golgi network(GO:0005801)
0.0 1.1 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 1.2 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.4 GO:0036038 MKS complex(GO:0036038)
0.0 0.7 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 0.1 GO:0005940 septin ring(GO:0005940)
0.0 0.2 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.2 GO:0036156 inner dynein arm(GO:0036156)
0.0 0.1 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 0.3 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.1 GO:0044214 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.0 0.2 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 2.1 GO:0010008 endosome membrane(GO:0010008)
0.0 2.2 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.2 GO:0004967 glucagon receptor activity(GO:0004967)
0.8 5.8 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.6 2.3 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.5 2.0 GO:0048408 epidermal growth factor binding(GO:0048408)
0.4 1.9 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.3 1.5 GO:0070012 oligopeptidase activity(GO:0070012)
0.3 1.5 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.3 1.4 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.2 1.2 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
0.2 0.8 GO:0070976 TIR domain binding(GO:0070976)
0.2 1.4 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.2 0.6 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.2 1.0 GO:0071723 lipopeptide binding(GO:0071723)
0.2 0.5 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.1 0.9 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.1 1.0 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.1 1.0 GO:0016892 endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.1 0.4 GO:0071633 dihydroceramidase activity(GO:0071633)
0.1 0.4 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.1 0.7 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.1 1.0 GO:0046790 virion binding(GO:0046790)
0.1 0.9 GO:0097322 7SK snRNA binding(GO:0097322)
0.1 0.4 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.1 0.7 GO:0005499 vitamin D binding(GO:0005499)
0.1 0.9 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 0.9 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 2.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 1.6 GO:0004806 triglyceride lipase activity(GO:0004806)
0.1 0.6 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.1 0.2 GO:0042936 dipeptide transporter activity(GO:0042936)
0.1 1.0 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 0.2 GO:0005110 frizzled-2 binding(GO:0005110)
0.1 0.8 GO:0051525 NFAT protein binding(GO:0051525)
0.1 1.0 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 1.0 GO:0005243 gap junction channel activity(GO:0005243)
0.1 0.2 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745) peptidoglycan receptor activity(GO:0016019)
0.1 3.3 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.1 0.7 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 0.2 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280) L-tyrosine transmembrane transporter activity(GO:0005302)
0.1 0.8 GO:0070403 NAD+ binding(GO:0070403)
0.1 1.6 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 0.9 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.4 GO:0045545 syndecan binding(GO:0045545)
0.0 0.6 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.6 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.5 GO:0005338 nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.0 0.4 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 0.3 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.2 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 0.4 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 1.3 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.5 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 2.2 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.5 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.9 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.3 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 3.9 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 0.5 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.2 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0 0.8 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 1.4 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.3 GO:0016004 phospholipase activator activity(GO:0016004) lipase activator activity(GO:0060229)
0.0 0.1 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.0 0.2 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.3 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 1.0 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.5 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.4 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.1 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.5 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.2 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.0 0.2 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.4 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.2 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.4 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.2 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 0.8 GO:0070888 E-box binding(GO:0070888)
0.0 0.2 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.7 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 1.6 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.1 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 1.9 GO:0008236 serine-type peptidase activity(GO:0008236)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 4.0 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.1 2.0 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.1 2.2 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.1 1.5 PID ARF 3PATHWAY Arf1 pathway
0.0 1.5 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 1.6 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 1.2 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 1.4 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 1.7 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 1.1 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.6 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 1.3 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.3 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 1.0 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.8 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.6 PID ALK1 PATHWAY ALK1 signaling events
0.0 1.4 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 2.0 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.9 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.5 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.1 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 0.1 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.8 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.2 2.3 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 1.5 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.1 5.3 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.1 1.1 REACTOME DEFENSINS Genes involved in Defensins
0.1 2.0 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.1 1.0 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 1.0 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 1.1 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 2.0 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 0.9 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 3.0 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.1 1.0 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.1 1.1 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.1 3.2 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.1 1.3 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 0.5 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.1 1.0 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1 1.0 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.9 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.3 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.5 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.5 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.2 REACTOME OPSINS Genes involved in Opsins
0.0 0.6 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.9 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.8 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.4 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.6 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.4 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.3 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.4 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.6 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.8 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 4.0 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.4 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.4 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.5 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling