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12D miR HR13_24

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Results for Trp53

Z-value: 1.38

Motif logo

Transcription factors associated with Trp53

Gene Symbol Gene ID Gene Info
ENSMUSG00000059552.7 transformation related protein 53

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Trp53mm10_v2_chr11_+_69580359_695803820.821.9e-03Click!

Activity profile of Trp53 motif

Sorted Z-values of Trp53 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_40755201 3.96 ENSMUST00000020576.7
cyclin G1
chr17_+_29090969 3.69 ENSMUST00000119901.1
cyclin-dependent kinase inhibitor 1A (P21)
chr5_-_38480131 1.76 ENSMUST00000143758.1
ENSMUST00000067886.5
solute carrier family 2 (facilitated glucose transporter), member 9
chr1_-_79858627 1.60 ENSMUST00000027467.4
serine (or cysteine) peptidase inhibitor, clade E, member 2
chr15_+_62039216 1.58 ENSMUST00000183297.1
plasmacytoma variant translocation 1
chr15_+_85859689 1.40 ENSMUST00000170629.1
G two S phase expressed protein 1
chr8_-_22185758 1.35 ENSMUST00000046916.7
cytoskeleton associated protein 2
chr2_+_152962485 1.33 ENSMUST00000099197.2
ENSMUST00000103155.3
tubulin tyrosine ligase-like family, member 9
chr15_-_102350692 1.32 ENSMUST00000041208.7
achalasia, adrenocortical insufficiency, alacrimia
chr7_+_16309577 1.30 ENSMUST00000002152.6
BCL2 binding component 3
chr14_-_118925314 1.22 ENSMUST00000004055.8
DAZ interacting protein 1
chr17_-_33890584 1.20 ENSMUST00000114361.2
ENSMUST00000173492.1
kinesin family member C1
chr7_-_24545994 1.10 ENSMUST00000011776.6
phospholipase A2 inhibitor and LY6/PLAUR domain containing
chr5_-_38502107 1.06 ENSMUST00000005238.6
solute carrier family 2 (facilitated glucose transporter), member 9
chr2_+_72285637 1.00 ENSMUST00000090824.5
ENSMUST00000135469.1
sterile alpha motif and leucine zipper containing kinase AZK
chr16_+_17144600 0.93 ENSMUST00000115702.1
YdjC homolog (bacterial)
chr17_-_33890539 0.92 ENSMUST00000173386.1
kinesin family member C1
chr7_+_19851994 0.91 ENSMUST00000172815.1
predicted gene, 19345
chr16_-_17144415 0.89 ENSMUST00000115709.1
coiled-coil domain containing 116
chr11_+_4267095 0.87 ENSMUST00000040750.3
leukemia inhibitory factor
chr9_+_66946057 0.71 ENSMUST00000040917.7
ENSMUST00000127896.1
ribosomal protein S27-like
chr11_-_95699143 0.70 ENSMUST00000062249.2
predicted gene 9796
chr19_-_10974664 0.70 ENSMUST00000072748.6
membrane-spanning 4-domains, subfamily A, member 10
chr6_-_116461024 0.63 ENSMUST00000164547.1
ENSMUST00000170186.1
arachidonate 5-lipoxygenase
chr2_+_129100995 0.63 ENSMUST00000103205.4
ENSMUST00000028874.7
polymerase (RNA) I polypeptide B
chr14_+_13454010 0.62 ENSMUST00000112656.2
synaptoporin
chr4_+_139622842 0.62 ENSMUST00000039818.9
aldehyde dehydrogenase 4 family, member A1
chr16_+_38458887 0.61 ENSMUST00000099816.2
CD80 antigen
chr8_-_106136890 0.61 ENSMUST00000115979.2
epithelial splicing regulatory protein 2
chr9_-_100486788 0.60 ENSMUST00000098458.3
interleukin 20 receptor beta
chr10_+_57631981 0.59 ENSMUST00000095668.3
ENSMUST00000075992.5
protein kinase inhibitor beta, cAMP dependent, testis specific
chr3_+_79885930 0.58 ENSMUST00000029567.8
family with sequence similarity 198, member B
chr1_-_173982842 0.56 ENSMUST00000000266.7
interferon activated gene 202B
chr7_+_47050628 0.56 ENSMUST00000010451.5
transmembrane protein 86A
chr5_+_8798139 0.54 ENSMUST00000009058.5
ATP-binding cassette, sub-family B (MDR/TAP), member 1B
chr13_-_12520377 0.53 ENSMUST00000179308.1
EDAR (ectodysplasin-A receptor)-associated death domain
chr5_+_92392585 0.52 ENSMUST00000126281.1
ADP-ribosyltransferase 3
chr14_+_47001336 0.51 ENSMUST00000125113.1
sterile alpha motif domain containing 4
chr10_+_57632108 0.49 ENSMUST00000177438.1
protein kinase inhibitor beta, cAMP dependent, testis specific
chr1_+_55237177 0.49 ENSMUST00000061334.8
methionine-tRNA synthetase 2 (mitochondrial)
chr14_-_55944536 0.48 ENSMUST00000022834.6
chymase 1, mast cell
chr1_+_133350510 0.46 ENSMUST00000094556.2
renin 1 structural
chr13_-_22035589 0.46 ENSMUST00000091742.4
histone cluster 1, H2ah
chr11_+_87582201 0.46 ENSMUST00000133202.1
septin 4
chr7_-_19458494 0.45 ENSMUST00000085715.5
MAP/microtubule affinity-regulating kinase 4
chr4_-_134254076 0.43 ENSMUST00000060050.5
glycine/arginine rich protein 1
chr17_+_12584183 0.43 ENSMUST00000046959.7
solute carrier family 22 (organic cation transporter), member 2
chr17_+_3532554 0.42 ENSMUST00000168560.1
claudin 20
chr11_-_102925086 0.41 ENSMUST00000021311.9
kinesin family member 18B
chr11_+_118476824 0.41 ENSMUST00000135383.2
endo-beta-N-acetylglucosaminidase
chr6_-_116461151 0.41 ENSMUST00000026795.6
arachidonate 5-lipoxygenase
chr16_-_94856682 0.40 ENSMUST00000165538.1
potassium inwardly-rectifying channel, subfamily J, member 6
chr4_+_141213948 0.38 ENSMUST00000097813.2
REM2 and RAB-like small GTPase 1
chr3_-_92573715 0.38 ENSMUST00000053107.4
involucrin
chr5_-_116422858 0.38 ENSMUST00000036991.4
heat shock protein 8
chr1_-_191907527 0.38 ENSMUST00000069573.5
RIKEN cDNA 1700034H15 gene
chr9_-_106656081 0.38 ENSMUST00000023959.7
glutamate receptor, metabotropic 2
chr9_-_106158109 0.38 ENSMUST00000159809.1
ENSMUST00000162562.1
ENSMUST00000036382.6
ENSMUST00000112543.2
glycerate kinase
chr4_-_96591555 0.38 ENSMUST00000055693.8
cytochrome P450, family 2, subfamily j, polypeptide 9
chr15_-_98898483 0.37 ENSMUST00000023737.4
desert hedgehog
chr1_-_184883218 0.35 ENSMUST00000048308.5
RIKEN cDNA C130074G19 gene
chr13_+_21754067 0.32 ENSMUST00000091709.2
histone cluster 1, H2bn
chr16_-_11909398 0.32 ENSMUST00000127972.1
ENSMUST00000121750.1
ENSMUST00000096272.4
ENSMUST00000073371.6
calcineurin-like phosphoesterase domain containing 1
chr14_-_59365410 0.31 ENSMUST00000161031.1
ENSMUST00000160425.1
PHD finger protein 11D
chr5_-_66080971 0.31 ENSMUST00000127275.1
ENSMUST00000113724.1
RNA binding motif protein 47
chr17_+_26917091 0.31 ENSMUST00000078961.4
kinesin family member C5B
chr14_+_13453937 0.31 ENSMUST00000153954.1
synaptoporin
chr3_+_64081642 0.31 ENSMUST00000029406.4
vomeronasal 2, receptor 1
chrX_-_73435332 0.30 ENSMUST00000033738.7
three prime repair exonuclease 2
chr17_+_28207778 0.30 ENSMUST00000002327.5
differentially expressed in FDCP 6
chr14_-_59365465 0.30 ENSMUST00000095157.4
PHD finger protein 11D
chr16_+_57353093 0.30 ENSMUST00000159816.1
filamin A interacting protein 1-like
chr12_-_78906929 0.28 ENSMUST00000021544.7
pleckstrin 2
chr13_+_23574381 0.27 ENSMUST00000090776.4
histone cluster 1, H2ad
chr13_+_22035821 0.27 ENSMUST00000110455.2
histone cluster 1, H2bk
chr4_-_155056784 0.26 ENSMUST00000131173.2
phospholipase C, eta 2
chr19_+_4855129 0.25 ENSMUST00000119694.1
cathepsin F
chr17_+_27685197 0.25 ENSMUST00000097360.2
protein kinase C and casein kinase substrate in neurons 1
chr2_-_163397946 0.25 ENSMUST00000017961.4
ENSMUST00000109425.2
junctophilin 2
chr7_+_24884611 0.25 ENSMUST00000108428.1
ribosomal protein S19
chr5_+_52363925 0.25 ENSMUST00000101208.4
superoxide dismutase 3, extracellular
chr2_+_29889217 0.24 ENSMUST00000123335.1
outer dense fiber of sperm tails 2
chr7_+_24884809 0.24 ENSMUST00000156372.1
ENSMUST00000124035.1
ribosomal protein S19
chr5_-_115194283 0.24 ENSMUST00000112113.1
calcium binding protein 1
chr7_+_24884651 0.23 ENSMUST00000153451.2
ENSMUST00000108429.1
ribosomal protein S19
chr19_-_43524462 0.23 ENSMUST00000026196.7
glutamate oxaloacetate transaminase 1, soluble
chr17_-_45595842 0.23 ENSMUST00000164618.1
ENSMUST00000097317.3
ENSMUST00000170113.1
solute carrier family 29 (nucleoside transporters), member 1
chr19_-_47138280 0.23 ENSMUST00000140512.1
ENSMUST00000035822.1
calcium homeostasis modulator 2
chr11_-_83429455 0.23 ENSMUST00000052521.2
growth arrest-specific 2 like 2
chr12_-_26415256 0.22 ENSMUST00000020971.6
ENSMUST00000062149.4
ring finger protein 144A
chr1_-_22315792 0.22 ENSMUST00000164877.1
regulating synaptic membrane exocytosis 1
chr4_+_116596672 0.21 ENSMUST00000051869.7
coiled-coil domain containing 17
chr11_+_102835849 0.21 ENSMUST00000107073.1
HIG1 domain family, member 1B
chr13_-_98815408 0.21 ENSMUST00000040340.8
ENSMUST00000099277.4
ENSMUST00000179563.1
ENSMUST00000109403.1
FCH domain only 2
chr9_-_59486323 0.21 ENSMUST00000165322.1
ariadne ubiquitin-conjugating enzyme E2 binding protein homolog 1 (Drosophila)
chr1_+_51289106 0.21 ENSMUST00000051572.6
serum deprivation response
chr10_+_79822617 0.20 ENSMUST00000046833.4
mitotic spindle positioning
chr9_+_38773088 0.20 ENSMUST00000062124.3
olfactory receptor 921
chr9_+_77636494 0.19 ENSMUST00000057781.7
kelch-like 31
chr17_-_35066170 0.19 ENSMUST00000174190.1
ENSMUST00000097337.1
expressed sequence AU023871
chr14_-_20496780 0.19 ENSMUST00000022353.3
MSS51 mitochondrial translational activator
chr5_-_38502079 0.18 ENSMUST00000147664.1
solute carrier family 2 (facilitated glucose transporter), member 9
chr2_-_155592567 0.18 ENSMUST00000155347.1
ENSMUST00000130881.1
ENSMUST00000079691.6
glutathione synthetase
chr7_-_24760311 0.18 ENSMUST00000063956.5
CD177 antigen
chr4_-_9643638 0.17 ENSMUST00000108333.1
ENSMUST00000108334.1
ENSMUST00000108335.1
ENSMUST00000152526.1
ENSMUST00000103004.3
aspartate-beta-hydroxylase
chr4_-_156059414 0.17 ENSMUST00000184348.1
tubulin tyrosine ligase-like family, member 10
chr3_-_132950043 0.16 ENSMUST00000117164.1
ENSMUST00000093971.4
ENSMUST00000042729.9
ENSMUST00000042744.9
ENSMUST00000117811.1
nephronectin
chr7_+_130936172 0.16 ENSMUST00000006367.7
HtrA serine peptidase 1
chr9_+_65361049 0.16 ENSMUST00000147185.1
predicted gene 514
chr9_+_49518336 0.16 ENSMUST00000068730.3
predicted gene 11149
chr2_+_86007778 0.16 ENSMUST00000062166.1
olfactory receptor 1032
chrX_+_136822781 0.16 ENSMUST00000113085.1
proteolipid protein (myelin) 1
chr10_+_110745433 0.16 ENSMUST00000174857.1
ENSMUST00000073781.5
ENSMUST00000173471.1
ENSMUST00000173634.1
E2F transcription factor 7
chr4_-_149099802 0.16 ENSMUST00000103217.4
peroxisomal biogenesis factor 14
chr1_+_6487231 0.15 ENSMUST00000140079.1
ENSMUST00000131494.1
suppression of tumorigenicity 18
chr17_+_78882003 0.15 ENSMUST00000180880.1
predicted gene, 26637
chr14_-_103843685 0.15 ENSMUST00000172237.1
endothelin receptor type B
chr7_+_18718075 0.14 ENSMUST00000108481.1
ENSMUST00000051973.8
pregnancy-specific glycoprotein 22
chr2_+_136891501 0.14 ENSMUST00000141463.1
SLX4 interacting protein
chr16_+_91391721 0.14 ENSMUST00000160764.1
predicted gene 21970
chr8_-_88636117 0.14 ENSMUST00000034087.7
sorting nexin 20
chr2_+_10372426 0.14 ENSMUST00000114864.2
ENSMUST00000116594.2
ENSMUST00000041105.6
Scm-like with four mbt domains 2
chr17_+_24840108 0.13 ENSMUST00000164251.1
hydroxyacyl glutathione hydrolase
chr11_-_116168138 0.13 ENSMUST00000139020.1
ENSMUST00000103031.1
ENSMUST00000124828.1
Fas (TNFRSF6) binding factor 1
chr4_+_43983496 0.13 ENSMUST00000095107.1
calicin
chr1_-_52232296 0.13 ENSMUST00000114512.1
glutaminase
chr1_-_193130201 0.12 ENSMUST00000085555.1
digestive organ expansion factor homolog (zebrafish)
chr14_-_78725089 0.12 ENSMUST00000074729.5
diacylglycerol kinase, eta
chrX_+_136822671 0.12 ENSMUST00000033800.6
proteolipid protein (myelin) 1
chr14_-_70653081 0.12 ENSMUST00000062629.4
nucleophosmin/nucleoplasmin 2
chr8_-_93079965 0.12 ENSMUST00000109582.1
carboxylesterase 1B
chr11_-_32267547 0.12 ENSMUST00000109389.2
ENSMUST00000129010.1
ENSMUST00000020530.5
nitrogen permease regulator-like 3
chr8_-_71676674 0.11 ENSMUST00000066837.4
predicted gene 9933
chr4_+_102430047 0.11 ENSMUST00000172616.1
phosphodiesterase 4B, cAMP specific
chr7_-_98309471 0.10 ENSMUST00000033020.7
alkaline ceramidase 3
chr7_-_141010759 0.10 ENSMUST00000026565.6
interferon induced transmembrane protein 3
chr4_-_135573623 0.10 ENSMUST00000105855.1
grainyhead-like 3 (Drosophila)
chr11_+_49280150 0.10 ENSMUST00000078932.1
olfactory receptor 1393
chr8_-_105851981 0.10 ENSMUST00000040776.4
centromere protein T
chr9_-_26999491 0.10 ENSMUST00000060513.7
ENSMUST00000120367.1
acyl-Coenzyme A dehydrogenase family, member 8
chr15_+_83791939 0.10 ENSMUST00000172115.1
ENSMUST00000172398.1
metallophosphoesterase domain containing 1
chr7_+_142498832 0.10 ENSMUST00000078497.8
ENSMUST00000105953.3
ENSMUST00000179658.1
ENSMUST00000105954.3
ENSMUST00000105952.3
ENSMUST00000105955.1
ENSMUST00000074187.6
ENSMUST00000180152.1
ENSMUST00000105950.4
ENSMUST00000105957.3
ENSMUST00000169299.2
ENSMUST00000105958.3
ENSMUST00000105949.1
troponin T3, skeletal, fast
chr6_-_38837224 0.09 ENSMUST00000160962.1
homeodomain interacting protein kinase 2
chr3_-_146495115 0.09 ENSMUST00000093951.2
spermatogenesis associated 1
chr8_-_9977650 0.09 ENSMUST00000170033.1
ligase IV, DNA, ATP-dependent
chrX_-_101734125 0.09 ENSMUST00000056614.6
chemokine (C-X-C motif) receptor 3
chr9_+_78395777 0.09 ENSMUST00000113367.1
DEAD (Asp-Glu-Ala-Asp) box polypeptide 43
chr9_+_122117258 0.09 ENSMUST00000146832.1
ENSMUST00000139181.1
SNF related kinase
chr7_+_64392645 0.08 ENSMUST00000037205.8
methylmalonyl CoA epimerase
chr11_+_66911981 0.08 ENSMUST00000123434.2
phosphoinositide-interacting regulator of transient receptor potential channels
chr16_-_45408875 0.08 ENSMUST00000023341.8
CD200 antigen
chr13_-_23574196 0.08 ENSMUST00000105106.1
histone cluster 1, H2bf
chr12_-_55492587 0.07 ENSMUST00000021413.7
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha
chr15_-_102246439 0.07 ENSMUST00000063339.7
retinoic acid receptor, gamma
chr4_-_14796052 0.07 ENSMUST00000108276.1
ENSMUST00000023917.1
leucine rich repeat containing 69
chr8_+_9977707 0.06 ENSMUST00000139793.1
ENSMUST00000048216.5
abhydrolase domain containing 13
chr16_-_20316750 0.06 ENSMUST00000182741.1
cytochrome P450, family 2, subfamily ab, polypeptide 1
chr7_-_92637079 0.06 ENSMUST00000056106.7
ENSMUST00000118157.1
ankyrin repeat domain 42
chr13_+_24376070 0.06 ENSMUST00000050859.5
cytidine monophospho-N-acetylneuraminic acid hydroxylase
chr4_+_108459389 0.06 ENSMUST00000106673.1
ENSMUST00000043368.5
zinc finger, CCHC domain containing 11
chr13_+_59712284 0.06 ENSMUST00000165133.1
spermatogenesis associated 31 subfamily D, member 1B
chr16_-_45408955 0.06 ENSMUST00000163230.1
CD200 antigen
chr17_-_24696147 0.06 ENSMUST00000046839.8
growth factor, erv1 (S. cerevisiae)-like (augmenter of liver regeneration)
chr9_+_65346066 0.05 ENSMUST00000048184.2
programmed cell death 7
chr5_-_138272786 0.05 ENSMUST00000161279.1
ENSMUST00000161647.1
galactose-3-O-sulfotransferase 4
chr9_-_14718381 0.05 ENSMUST00000115643.1
piwi-like RNA-mediated gene silencing 4
chr10_+_94550852 0.05 ENSMUST00000148910.1
ENSMUST00000117460.1
transmembrane and coiled coil domains 3
chr2_-_17731035 0.05 ENSMUST00000028080.5
nebulette
chr7_-_64872993 0.04 ENSMUST00000094331.2
necdin-like 2
chr6_+_127446819 0.04 ENSMUST00000112191.1
poly (ADP-ribose) polymerase family, member 11
chr6_+_71707561 0.04 ENSMUST00000121469.1
receptor accessory protein 1
chr11_+_55469677 0.04 ENSMUST00000018727.3
GTPase activating protein (SH3 domain) binding protein 1
chr7_+_30169861 0.04 ENSMUST00000085668.4
predicted gene 5113
chr6_-_128891105 0.04 ENSMUST00000178918.1
ENSMUST00000160290.1
cDNA sequence BC035044
chr4_+_148558422 0.04 ENSMUST00000017408.7
ENSMUST00000076022.6
exosome component 10
chr5_+_34999111 0.03 ENSMUST00000114283.1
regulator of G-protein signaling 12
chr4_-_43030440 0.03 ENSMUST00000135660.1
stomatin (Epb7.2)-like 2
chr1_+_161969179 0.03 ENSMUST00000111594.2
ENSMUST00000028021.6
phosphatidylinositol glycan anchor biosynthesis, class C
chr9_-_70141484 0.03 ENSMUST00000034749.8
family with sequence similarity 81, member A
chr19_-_4793851 0.03 ENSMUST00000178615.1
ENSMUST00000179189.1
ENSMUST00000164376.2
ENSMUST00000164209.2
ENSMUST00000180248.1
RNA binding motif protein 4
chr10_+_56377300 0.03 ENSMUST00000068581.7
gap junction protein, alpha 1
chr3_-_84304762 0.02 ENSMUST00000107692.1
tripartite motif-containing 2
chr9_+_108080436 0.02 ENSMUST00000035211.7
ENSMUST00000162886.1
macrophage stimulating 1 (hepatocyte growth factor-like)
chr7_+_5034118 0.02 ENSMUST00000076791.3
RIKEN cDNA 4632433K11 gene
chr5_+_34999046 0.02 ENSMUST00000114281.1
regulator of G-protein signaling 12
chr2_+_136892168 0.01 ENSMUST00000099311.2
SLX4 interacting protein
chr5_+_34999070 0.01 ENSMUST00000114280.1
regulator of G-protein signaling 12
chr3_+_96172327 0.01 ENSMUST00000076372.4
splicing factor 3b, subunit 4
chr18_+_80253274 0.01 ENSMUST00000131780.1
ENSMUST00000157056.1
PQ loop repeat containing 1
chr17_+_32506446 0.01 ENSMUST00000165999.1
cytochrome P450, family 4, subfamily f, polypeptide 17
chr7_+_24399921 0.01 ENSMUST00000108434.1
smg-9 homolog, nonsense mediated mRNA decay factor (C. elegans)
chr10_+_80622677 0.01 ENSMUST00000079773.6
casein kinase 1, gamma 2
chr17_+_52602700 0.01 ENSMUST00000039366.10
potassium voltage-gated channel, subfamily H (eag-related), member 8
chr18_-_35703108 0.01 ENSMUST00000025208.5
DnaJ (Hsp40) homolog, subfamily C, member 18
chr8_-_84893887 0.01 ENSMUST00000003907.7
ENSMUST00000182458.1
ENSMUST00000109745.1
ENSMUST00000142748.1
glutaryl-Coenzyme A dehydrogenase
chr8_+_35587780 0.00 ENSMUST00000037666.5
malignant fibrous histiocytoma amplified sequence 1
chr17_-_21933022 0.00 ENSMUST00000074295.7
zinc finger protein 942
chr1_+_161969284 0.00 ENSMUST00000160881.1
ENSMUST00000159648.1
phosphatidylinositol glycan anchor biosynthesis, class C
chr2_+_29890063 0.00 ENSMUST00000028128.6
outer dense fiber of sperm tails 2
chr11_+_88204396 0.00 ENSMUST00000118784.1
ENSMUST00000139170.1
ENSMUST00000107915.3
ENSMUST00000144070.1
mitochondrial ribosomal protein S23

Network of associatons between targets according to the STRING database.

First level regulatory network of Trp53

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0072382 minus-end-directed vesicle transport along microtubule(GO:0072382)
0.3 3.3 GO:0071493 cellular response to UV-B(GO:0071493)
0.3 1.6 GO:0061110 dense core granule biogenesis(GO:0061110)
0.3 1.0 GO:0002540 leukotriene production involved in inflammatory response(GO:0002540)
0.3 1.0 GO:1900740 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.2 0.9 GO:0072108 positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis(GO:0072108)
0.2 0.6 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.2 0.6 GO:0001807 regulation of type IV hypersensitivity(GO:0001807) negative regulation of hypersensitivity(GO:0002884)
0.2 3.0 GO:0046415 urate metabolic process(GO:0046415)
0.2 0.7 GO:0060265 positive regulation of respiratory burst involved in inflammatory response(GO:0060265)
0.2 0.5 GO:0042222 interleukin-1 biosynthetic process(GO:0042222)
0.2 3.7 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.2 0.5 GO:0002018 renin-angiotensin regulation of aldosterone production(GO:0002018)
0.1 0.5 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.1 0.6 GO:0007000 nucleolus organization(GO:0007000)
0.1 0.5 GO:0014045 establishment of endothelial blood-brain barrier(GO:0014045)
0.1 0.2 GO:0006533 fumarate metabolic process(GO:0006106) glycerol biosynthetic process(GO:0006114) aspartate biosynthetic process(GO:0006532) aspartate catabolic process(GO:0006533)
0.1 0.5 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.1 1.1 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 0.2 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.1 0.2 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
0.1 0.2 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
0.1 0.2 GO:0016561 protein import into peroxisome matrix, translocation(GO:0016561)
0.1 0.3 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.0 0.2 GO:0097195 pilomotor reflex(GO:0097195) positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.0 1.6 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.0 0.7 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.2 GO:0015862 uridine transport(GO:0015862)
0.0 0.3 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.4 GO:0006517 protein deglycosylation(GO:0006517)
0.0 0.4 GO:0015697 organic cation transport(GO:0015695) quaternary ammonium group transport(GO:0015697)
0.0 0.2 GO:0018094 protein polyglycylation(GO:0018094)
0.0 0.2 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
0.0 0.1 GO:0014826 vein smooth muscle contraction(GO:0014826)
0.0 1.3 GO:0051220 cytoplasmic sequestering of protein(GO:0051220)
0.0 0.1 GO:0006543 glutamine catabolic process(GO:0006543)
0.0 0.3 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 0.4 GO:0030238 male sex determination(GO:0030238)
0.0 0.1 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.0 0.5 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.3 GO:0019236 response to pheromone(GO:0019236)
0.0 0.4 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 0.3 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.0 0.1 GO:0033153 somatic diversification of T cell receptor genes(GO:0002568) somatic recombination of T cell receptor gene segments(GO:0002681) T cell receptor V(D)J recombination(GO:0033153) double-strand break repair via classical nonhomologous end joining(GO:0097680)
0.0 0.1 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.0 0.1 GO:0046381 CMP-N-acetylneuraminate metabolic process(GO:0046381)
0.0 0.1 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0 0.0 GO:0003347 epicardial cell to mesenchymal cell transition(GO:0003347)
0.0 0.6 GO:0060441 epithelial tube branching involved in lung morphogenesis(GO:0060441)
0.0 0.2 GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.0 0.6 GO:0035458 cellular response to interferon-beta(GO:0035458)
0.0 0.1 GO:0035456 response to interferon-beta(GO:0035456)
0.0 0.4 GO:0010107 potassium ion import(GO:0010107)
0.0 0.1 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.0 GO:0090297 positive regulation of mitochondrial DNA replication(GO:0090297) regulation of cardiolipin metabolic process(GO:1900208) positive regulation of cardiolipin metabolic process(GO:1900210) stress-induced mitochondrial fusion(GO:1990046)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.7 GO:0070557 PCNA-p21 complex(GO:0070557)
0.1 1.6 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.1 1.6 GO:0097539 ciliary transition fiber(GO:0097539)
0.1 1.9 GO:0031616 spindle pole centrosome(GO:0031616)
0.1 0.4 GO:0000235 astral microtubule(GO:0000235)
0.1 0.2 GO:0098833 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835)
0.1 1.0 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 0.5 GO:0097227 sperm annulus(GO:0097227)
0.0 0.2 GO:0098831 presynaptic active zone cytoplasmic component(GO:0098831)
0.0 0.5 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.9 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 2.7 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.2 GO:1990415 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.0 0.6 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.3 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.2 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 1.4 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.2 GO:0097413 Lewy body(GO:0097413)
0.0 0.2 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.6 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.1 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.3 GO:0001533 cornified envelope(GO:0001533)
0.0 0.1 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) DNA ligase IV complex(GO:0032807)
0.0 1.4 GO:0005643 nuclear pore(GO:0005643)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.7 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.3 1.0 GO:0004051 arachidonate 5-lipoxygenase activity(GO:0004051)
0.3 3.0 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.2 0.9 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.2 0.6 GO:0042015 interleukin-20 binding(GO:0042015)
0.2 1.1 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.1 0.4 GO:0005333 norepinephrine transmembrane transporter activity(GO:0005333)
0.1 0.7 GO:0008494 translation activator activity(GO:0008494)
0.1 0.5 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.1 0.2 GO:0070546 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069) L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.1 2.1 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.1 0.4 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 0.3 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.1 0.4 GO:0005113 patched binding(GO:0005113)
0.1 0.2 GO:0070737 protein-glycine ligase activity, elongating(GO:0070737)
0.1 1.1 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.2 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.1 GO:0004962 endothelin receptor activity(GO:0004962)
0.0 0.4 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640)
0.0 0.6 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.5 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 0.6 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 0.2 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.1 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.0 0.5 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.1 GO:0004920 interleukin-10 receptor activity(GO:0004920)
0.0 0.5 GO:0005123 death receptor binding(GO:0005123)
0.0 0.1 GO:0004359 glutaminase activity(GO:0004359)
0.0 0.7 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.1 GO:0030338 CMP-N-acetylneuraminate monooxygenase activity(GO:0030338)
0.0 0.5 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.0 0.5 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0019958 C-X-C chemokine binding(GO:0019958)
0.0 0.1 GO:0045545 syndecan binding(GO:0045545)
0.0 0.1 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.1 GO:0034511 U3 snoRNA binding(GO:0034511)
0.0 0.4 GO:0005549 odorant binding(GO:0005549)
0.0 0.1 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0 0.1 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0 0.0 GO:0034584 piRNA binding(GO:0034584)
0.0 0.1 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.0 0.3 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 1.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.1 GO:0046790 virion binding(GO:0046790)
0.0 0.1 GO:0003909 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.7 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 1.0 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 4.1 PID P53 REGULATION PATHWAY p53 pathway
0.0 1.3 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.6 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.4 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.0 PID P73PATHWAY p73 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.0 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 3.7 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.1 2.1 REACTOME KINESINS Genes involved in Kinesins
0.1 1.0 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.6 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 1.3 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 0.6 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.9 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.6 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.5 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.4 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.5 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.2 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.7 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.1 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle