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12D miR HR13_24

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Results for Spib

Z-value: 1.76

Motif logo

Transcription factors associated with Spib

Gene Symbol Gene ID Gene Info
ENSMUSG00000008193.7 Spi-B transcription factor (Spi-1/PU.1 related)

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Spibmm10_v2_chr7_-_44532064_44532078-0.029.6e-01Click!

Activity profile of Spib motif

Sorted Z-values of Spib motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_86988676 2.51 ENSMUST00000095521.2
zinc finger, DHHC-type containing 22
chr1_+_16688405 2.18 ENSMUST00000026881.4
lymphocyte antigen 96
chr2_+_24386604 1.83 ENSMUST00000166388.1
pleckstrin and Sec7 domain containing 4
chrX_+_107816477 1.76 ENSMUST00000143975.1
ENSMUST00000144695.1
ENSMUST00000167154.1
family with sequence similarity 46, member D
chr15_-_78305603 1.71 ENSMUST00000096356.3
colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage)
chr16_+_5007283 1.70 ENSMUST00000184439.1
small integral membrane protein 22
chr8_-_54529951 1.60 ENSMUST00000067476.8
signal peptidase complex subunit 3 homolog (S. cerevisiae)
chr2_+_24345305 1.46 ENSMUST00000114482.1
interleukin 1 receptor antagonist
chr13_-_13393592 1.45 ENSMUST00000021738.8
G protein-coupled receptor 137B
chr7_-_3845050 1.39 ENSMUST00000108615.3
ENSMUST00000119469.1
paired-Ig-like receptor A2
chr5_-_123141067 1.37 ENSMUST00000162697.1
ENSMUST00000160321.1
ENSMUST00000159637.1
expressed sequence AI480526
chr10_-_20724696 1.36 ENSMUST00000170265.1
phosphodiesterase 7B
chr12_+_33957645 1.32 ENSMUST00000049089.5
twist basic helix-loop-helix transcription factor 1
chr12_-_78980758 1.26 ENSMUST00000174072.1
transmembrane protein 229B
chr7_-_3898120 1.25 ENSMUST00000070639.7
predicted gene 14548
chr7_-_3720382 1.25 ENSMUST00000078451.6
paired Ig-like receptor B
chr7_-_45238794 1.25 ENSMUST00000098461.1
ENSMUST00000107797.1
CD37 antigen
chr6_-_34955903 1.22 ENSMUST00000147169.1
RIKEN cDNA 2010107G12 gene
chr5_+_149265035 1.21 ENSMUST00000130144.1
ENSMUST00000071130.3
arachidonate 5-lipoxygenase activating protein
chr2_+_24345282 1.20 ENSMUST00000114485.2
interleukin 1 receptor antagonist
chr8_+_10006656 1.19 ENSMUST00000033892.7
tumor necrosis factor (ligand) superfamily, member 13b
chr11_+_78324200 1.18 ENSMUST00000102478.3
aldolase C, fructose-bisphosphate
chr11_-_69685537 1.17 ENSMUST00000018896.7
tumor necrosis factor (ligand) superfamily, member 13
chr15_+_39745926 1.17 ENSMUST00000022913.4
dentrocyte expressed seven transmembrane protein
chr16_-_22439719 1.16 ENSMUST00000079601.6
ets variant gene 5
chr4_+_62663620 1.13 ENSMUST00000126338.1
regulator of G-protein signaling 3
chr17_+_48232755 1.12 ENSMUST00000113251.3
ENSMUST00000048782.6
triggering receptor expressed on myeloid cells 1
chr6_-_124733121 1.08 ENSMUST00000112484.3
protein tyrosine phosphatase, non-receptor type 6
chr2_+_43555321 1.08 ENSMUST00000028223.2
kynureninase (L-kynurenine hydrolase)
chr11_-_115062177 1.08 ENSMUST00000062787.7
CD300e antigen
chr11_+_69991633 1.01 ENSMUST00000108592.1
gamma-aminobutyric acid receptor associated protein
chr3_+_135825788 1.00 ENSMUST00000167390.1
solute carrier family 39 (metal ion transporter), member 8
chr18_-_6241486 1.00 ENSMUST00000025083.7
kinesin family member 5B
chr1_-_131279544 0.99 ENSMUST00000062108.3
inhibitor of kappaB kinase epsilon
chr1_-_132139666 0.99 ENSMUST00000027697.5
cyclin-dependent kinase 18
chr3_+_135825648 0.98 ENSMUST00000180196.1
solute carrier family 39 (metal ion transporter), member 8
chr5_-_134229581 0.97 ENSMUST00000111275.1
ENSMUST00000016094.6
ENSMUST00000144086.1
neutrophil cytosolic factor 1
chr1_-_132139605 0.96 ENSMUST00000112362.2
cyclin-dependent kinase 18
chrX_+_159708593 0.95 ENSMUST00000080394.6
SH3-domain kinase binding protein 1
chr19_+_6341121 0.93 ENSMUST00000025897.6
ENSMUST00000130382.1
mitogen-activated protein kinase kinase kinase kinase 2
chr5_+_81021202 0.90 ENSMUST00000117253.1
ENSMUST00000120128.1
latrophilin 3
chr19_-_40994133 0.89 ENSMUST00000117695.1
B cell linker
chrX_-_38456407 0.89 ENSMUST00000074913.5
ENSMUST00000016678.7
ENSMUST00000061755.8
lysosomal-associated membrane protein 2
chr5_-_116024475 0.88 ENSMUST00000111999.1
protein kinase, AMP-activated, beta 1 non-catalytic subunit
chr1_-_156035891 0.87 ENSMUST00000126448.1
torsin A interacting protein 1
chr6_+_129350237 0.86 ENSMUST00000065289.4
C-type lectin domain family 12, member a
chr4_-_43454600 0.85 ENSMUST00000098105.3
ENSMUST00000098104.3
ENSMUST00000030179.4
CD72 antigen
chr3_-_101924378 0.82 ENSMUST00000106928.3
solute carrier family 22 (organic anion/cation transporter), member 15
chr1_-_171059390 0.82 ENSMUST00000164044.1
ENSMUST00000169017.1
Fc receptor, IgG, low affinity III
chr7_+_3290553 0.81 ENSMUST00000096744.5
myeloid-associated differentiation marker
chr8_-_11478618 0.81 ENSMUST00000033900.5
RAB20, member RAS oncogene family
chr7_-_45239108 0.80 ENSMUST00000033063.6
CD37 antigen
chr4_+_130913264 0.79 ENSMUST00000156225.1
ENSMUST00000156742.1
lysosomal-associated protein transmembrane 5
chr11_-_119355484 0.78 ENSMUST00000100172.2
ENSMUST00000005173.4
N-sulfoglucosamine sulfohydrolase (sulfamidase)
chr10_+_75893398 0.76 ENSMUST00000009236.4
Der1-like domain family, member 3
chr6_-_112946754 0.75 ENSMUST00000113169.2
SLIT-ROBO Rho GTPase activating protein 3
chr6_+_122308684 0.75 ENSMUST00000007602.8
ENSMUST00000112610.1
mannose-6-phosphate receptor, cation dependent
chr15_+_78325990 0.74 ENSMUST00000096355.3
colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
chr4_-_154160632 0.74 ENSMUST00000105639.3
ENSMUST00000030896.8
transformation related protein 63 regulated like
chr3_+_83766300 0.73 ENSMUST00000029625.7
secreted frizzled-related protein 2
chr1_-_170976112 0.73 ENSMUST00000027966.7
ENSMUST00000081103.5
ENSMUST00000159688.1
Fc receptor, IgG, low affinity IIb
chr11_+_82045705 0.73 ENSMUST00000021011.2
chemokine (C-C motif) ligand 7
chr1_-_171294937 0.72 ENSMUST00000111302.3
ENSMUST00000080001.2
ubiquitin-fold modifier conjugating enzyme 1
chr10_-_127121125 0.70 ENSMUST00000164259.1
ENSMUST00000080975.4
amplified in osteosarcoma
chr18_-_4352944 0.70 ENSMUST00000025078.2
mitogen-activated protein kinase kinase kinase 8
chr9_+_106222598 0.70 ENSMUST00000062241.9
toll-like receptor 9
chr15_-_9529868 0.69 ENSMUST00000003981.4
interleukin 7 receptor
chr9_-_66919646 0.68 ENSMUST00000041139.7
RAB8B, member RAS oncogene family
chr1_-_130729249 0.67 ENSMUST00000171479.1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
chr6_-_88518760 0.67 ENSMUST00000032168.5
Sec61 alpha 1 subunit (S. cerevisiae)
chr7_+_24611314 0.66 ENSMUST00000073325.5
pleckstrin homology-like domain, family B, member 3
chrX_+_139563316 0.66 ENSMUST00000113027.1
ring finger protein 128
chrX_-_48454152 0.64 ENSMUST00000114958.1
E74-like factor 4 (ets domain transcription factor)
chr5_+_86071734 0.64 ENSMUST00000031171.7
signal transducing adaptor family member 1
chr13_-_31559333 0.64 ENSMUST00000170573.1
RIKEN cDNA A530084C06 gene
chr2_-_26604267 0.64 ENSMUST00000028286.5
1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta)
chr4_-_43454563 0.64 ENSMUST00000107926.1
CD72 antigen
chr7_+_99535439 0.63 ENSMUST00000098266.2
ENSMUST00000179755.1
arrestin, beta 1
chr4_-_43454582 0.62 ENSMUST00000107925.1
CD72 antigen
chr8_+_94923687 0.62 ENSMUST00000153448.1
ENSMUST00000074570.3
ENSMUST00000166802.1
G protein-coupled receptor 114
chr7_-_126897424 0.61 ENSMUST00000120007.1
transmembrane protein 219
chr4_-_109476666 0.60 ENSMUST00000030284.3
ring finger protein 11
chr7_-_45239041 0.60 ENSMUST00000131290.1
CD37 antigen
chr19_-_41385070 0.60 ENSMUST00000059672.7
phosphoinositide-3-kinase adaptor protein 1
chr2_+_43555342 0.60 ENSMUST00000112826.1
ENSMUST00000050511.6
kynureninase (L-kynurenine hydrolase)
chr3_-_89387132 0.59 ENSMUST00000107433.1
zinc finger and BTB domain containing 7B
chr14_+_58075115 0.59 ENSMUST00000074654.5
fibroblast growth factor 9
chr19_+_6363671 0.59 ENSMUST00000131252.1
splicing factor 1
chr9_-_53706211 0.59 ENSMUST00000068449.3
RAB39, member RAS oncogene family
chr1_-_171234290 0.59 ENSMUST00000079957.6
Fc receptor, IgE, high affinity I, gamma polypeptide
chr2_-_52558539 0.59 ENSMUST00000102760.3
ENSMUST00000102761.2
calcium channel, voltage-dependent, beta 4 subunit
chr6_-_83121385 0.58 ENSMUST00000146328.1
ENSMUST00000113936.3
ENSMUST00000032111.4
WW domain binding protein 1
chr11_+_11685909 0.58 ENSMUST00000065433.5
IKAROS family zinc finger 1
chr2_+_169633517 0.57 ENSMUST00000109157.1
teashirt zinc finger family member 2
chr17_-_83846769 0.57 ENSMUST00000000687.7
3-hydroxyanthranilate 3,4-dioxygenase
chr13_+_102693522 0.57 ENSMUST00000022124.3
ENSMUST00000171267.1
ENSMUST00000167144.1
ENSMUST00000170878.1
CD180 antigen
chrX_+_20703906 0.56 ENSMUST00000033383.2
ubiquitin specific peptidase 11
chr16_+_21423118 0.55 ENSMUST00000096191.4
ENSMUST00000096192.5
ENSMUST00000115397.1
ENSMUST00000118923.1
ENSMUST00000122235.1
ENSMUST00000117598.1
ENSMUST00000139473.1
vacuolar protein sorting 8 homolog (S. cerevisiae)
chr12_+_105784694 0.55 ENSMUST00000109901.2
ENSMUST00000168186.1
ENSMUST00000163473.1
ENSMUST00000170540.1
ENSMUST00000166735.1
ENSMUST00000170002.1
poly (A) polymerase alpha
chr4_-_140581774 0.54 ENSMUST00000147426.1
ENSMUST00000105797.2
Rho guanine nucleotide exchange factor (GEF) 10-like
chr6_-_112947246 0.54 ENSMUST00000088373.4
SLIT-ROBO Rho GTPase activating protein 3
chr3_+_106721893 0.54 ENSMUST00000106736.2
ENSMUST00000154973.1
ENSMUST00000131330.1
ENSMUST00000150513.1
ligand dependent nuclear receptor interacting factor 1
chr1_-_119504736 0.54 ENSMUST00000004565.8
v-ral simian leukemia viral oncogene homolog B (ras related)
chr11_+_87664274 0.52 ENSMUST00000092800.5
ring finger protein 43
chr14_+_75131499 0.52 ENSMUST00000125833.1
ENSMUST00000124499.1
lymphocyte cytosolic protein 1
chr2_+_126034967 0.52 ENSMUST00000110442.1
fibroblast growth factor 7
chr5_+_57718021 0.50 ENSMUST00000094783.3
ENSMUST00000068110.7
protocadherin 7
chr17_+_35517100 0.50 ENSMUST00000164242.2
ENSMUST00000045956.7
coiled-coil alpha-helical rod protein 1
chr3_+_106721672 0.50 ENSMUST00000098750.2
ENSMUST00000130105.1
ligand dependent nuclear receptor interacting factor 1
chr8_-_95434869 0.50 ENSMUST00000034249.6
gene trap locus 3
chr2_+_91096744 0.50 ENSMUST00000132741.2
spleen focus forming virus (SFFV) proviral integration oncogene
chr2_+_169632996 0.49 ENSMUST00000109159.2
teashirt zinc finger family member 2
chr15_+_103453782 0.49 ENSMUST00000047405.7
NCK associated protein 1 like
chr14_+_80000292 0.48 ENSMUST00000088735.3
olfactomedin 4
chr11_+_87664549 0.48 ENSMUST00000121782.2
ring finger protein 43
chr13_+_30659999 0.48 ENSMUST00000091672.6
ENSMUST00000110310.1
ENSMUST00000095914.5
dual specificity phosphatase 22
chr11_-_70514608 0.47 ENSMUST00000021179.3
vitelline membrane outer layer 1 homolog (chicken)
chr4_-_123750236 0.46 ENSMUST00000102636.3
akirin 1
chr19_+_6363719 0.46 ENSMUST00000113489.1
ENSMUST00000113488.1
splicing factor 1
chr4_-_136898803 0.46 ENSMUST00000046285.5
complement component 1, q subcomponent, alpha polypeptide
chr15_-_83033294 0.45 ENSMUST00000100377.4
Nfat activating molecule with ITAM motif 1
chr3_+_127633134 0.45 ENSMUST00000029587.7
neurogenin 2
chr11_-_58330319 0.45 ENSMUST00000065533.2
predicted gene 9900
chr19_-_8774431 0.45 ENSMUST00000010249.5
transmembrane protein 179B
chr11_-_117969176 0.44 ENSMUST00000054002.3
suppressor of cytokine signaling 3
chr6_+_137410721 0.44 ENSMUST00000167002.1
protein tyrosine phosphatase, receptor type, O
chr15_-_78572754 0.44 ENSMUST00000043214.6
RAS-related C3 botulinum substrate 2
chr13_+_111867931 0.44 ENSMUST00000128198.1
predicted gene 15326
chr4_+_130913120 0.44 ENSMUST00000151698.1
lysosomal-associated protein transmembrane 5
chr1_-_80213931 0.44 ENSMUST00000058748.1
family with sequence similarity 124, member B
chr2_+_113441064 0.43 ENSMUST00000081349.6
formin 1
chr13_-_103334429 0.43 ENSMUST00000167058.1
ENSMUST00000164111.1
microtubule associated serine/threonine kinase family member 4
chr5_-_24601961 0.43 ENSMUST00000030791.7
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr11_+_68432112 0.42 ENSMUST00000021283.7
phosphoinositide-3-kinase, regulatory subunit 5, p101
chr11_+_113657375 0.42 ENSMUST00000148736.1
ENSMUST00000142069.1
ENSMUST00000134418.1
component of oligomeric golgi complex 1
chr1_+_171682004 0.42 ENSMUST00000015499.7
ENSMUST00000068584.5
CD48 antigen
chr10_+_51480632 0.42 ENSMUST00000102894.3
ENSMUST00000105482.1
ENSMUST00000105481.1
glycoprotein 49 A
leukocyte immunoglobulin-like receptor, subfamily B, member 4
chr17_+_93199348 0.42 ENSMUST00000064775.6
adenylate cyclase activating polypeptide 1
chr5_-_116024452 0.41 ENSMUST00000031486.7
protein kinase, AMP-activated, beta 1 non-catalytic subunit
chr7_-_126463100 0.40 ENSMUST00000032974.6
ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
chr2_-_132815978 0.40 ENSMUST00000039554.6
tRNA methyltransferase 6
chrX_+_42149288 0.40 ENSMUST00000115073.2
ENSMUST00000115072.1
stromal antigen 2
chr2_-_104494400 0.40 ENSMUST00000028600.7
homeodomain interacting protein kinase 3
chr16_+_36934976 0.39 ENSMUST00000023531.8
hematopoietic cell specific Lyn substrate 1
chr6_-_136941694 0.39 ENSMUST00000032344.5
Rho, GDP dissociation inhibitor (GDI) beta
chr16_-_22657182 0.39 ENSMUST00000023578.7
diacylglycerol kinase, gamma
chr11_-_70812539 0.39 ENSMUST00000074572.6
ENSMUST00000108534.2
SLP adaptor and CSK interacting membrane protein
chr11_+_44400060 0.38 ENSMUST00000102796.3
ENSMUST00000170513.1
interleukin 12b
chr7_-_100856289 0.38 ENSMUST00000139604.1
RELT tumor necrosis factor receptor
chr1_+_109993982 0.37 ENSMUST00000027542.6
cadherin 7, type 2
chr10_+_80265035 0.37 ENSMUST00000092305.5
DAZ associated protein 1
chr9_+_56089962 0.36 ENSMUST00000059206.7
proline-serine-threonine phosphatase-interacting protein 1
chr11_-_115699307 0.36 ENSMUST00000106499.1
growth factor receptor bound protein 2
chr13_+_40859768 0.36 ENSMUST00000110191.2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme
chr5_-_138263942 0.35 ENSMUST00000048421.7
ENSMUST00000164203.1
cDNA sequence BC037034
cDNA sequence BC037034
chr4_-_136886187 0.35 ENSMUST00000046384.8
complement component 1, q subcomponent, beta polypeptide
chr13_-_23465872 0.35 ENSMUST00000041674.7
butyrophilin, subfamily 1, member A1
chr9_+_21526144 0.35 ENSMUST00000086361.5
ENSMUST00000179459.1
ENSMUST00000173769.2
cDNA sequence AB124611
chrX_+_73716577 0.35 ENSMUST00000002084.7
ATP-binding cassette, sub-family D (ALD), member 1
chr14_+_60378242 0.35 ENSMUST00000022561.6
APC membrane recruitment 2
chr12_-_78861636 0.34 ENSMUST00000021536.7
ATPase, H+ transporting, lysosomal V1 subunit D
chr5_-_66151903 0.34 ENSMUST00000167950.1
RNA binding motif protein 47
chr17_-_67950908 0.33 ENSMUST00000164647.1
Rho GTPase activating protein 28
chr9_+_65032722 0.33 ENSMUST00000167773.1
dipeptidylpeptidase 8
chrX_-_106603677 0.33 ENSMUST00000113480.1
cysteinyl leukotriene receptor 1
chr2_-_129309964 0.33 ENSMUST00000028882.1
interleukin 1 alpha
chr17_+_20945311 0.33 ENSMUST00000007708.7
protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform
chr17_+_34604262 0.33 ENSMUST00000174041.1
1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha)
chr7_-_47008397 0.33 ENSMUST00000061639.7
SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae)
chr19_-_11081088 0.32 ENSMUST00000025636.6
membrane-spanning 4-domains, subfamily A, member 8A
chr10_+_81393610 0.32 ENSMUST00000118206.1
RIKEN cDNA 2210404O07 gene
chr9_+_65032413 0.32 ENSMUST00000034960.6
dipeptidylpeptidase 8
chr4_-_124850670 0.31 ENSMUST00000163946.1
ENSMUST00000106190.3
RIKEN cDNA 1110065P20 gene
chr6_-_120822680 0.31 ENSMUST00000019354.8
ATPase, H+ transporting, lysosomal V1 subunit E1
chr9_+_94669876 0.31 ENSMUST00000033463.9
solute carrier family 9 (sodium/hydrogen exchanger), member 9
chr6_+_38918969 0.31 ENSMUST00000003017.6
thromboxane A synthase 1, platelet
chr2_+_156840966 0.30 ENSMUST00000109564.1
TGFB-induced factor homeobox 2
chr4_-_118489755 0.30 ENSMUST00000184261.1
tyrosine kinase with immunoglobulin-like and EGF-like domains 1
chr7_-_19118357 0.30 ENSMUST00000141380.1
predicted gene 4969
chr7_+_127769809 0.29 ENSMUST00000118865.1
ENSMUST00000061587.6
ENSMUST00000121504.1
ORAI calcium release-activated calcium modulator 3
chr2_+_25423234 0.29 ENSMUST00000134259.1
ENSMUST00000100320.4
fucosyltransferase 7
chr15_-_66812593 0.29 ENSMUST00000100572.3
src-like adaptor
chr16_+_41532851 0.29 ENSMUST00000078873.4
limbic system-associated membrane protein
chrX_-_43167817 0.28 ENSMUST00000115058.1
ENSMUST00000115059.1
teneurin transmembrane protein 1
chr12_-_32208609 0.28 ENSMUST00000053215.7
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr17_+_50509518 0.28 ENSMUST00000043938.6
phospholipase C-like 2
chr3_-_63899373 0.28 ENSMUST00000161052.2
phospholipase C, eta 1
chrX_-_74023908 0.28 ENSMUST00000033769.8
ENSMUST00000114352.1
ENSMUST00000068286.5
ENSMUST00000114360.3
ENSMUST00000114354.3
interleukin-1 receptor-associated kinase 1
chr12_-_84361802 0.28 ENSMUST00000021659.1
ENSMUST00000065536.2
family with sequence similarity 161, member B
chr17_-_35172608 0.27 ENSMUST00000173106.1
allograft inflammatory factor 1
chr11_+_69324055 0.27 ENSMUST00000102601.3
trafficking protein particle complex 1
chr17_+_35049966 0.27 ENSMUST00000007257.9
chloride intracellular channel 1
chr9_+_124102110 0.27 ENSMUST00000168841.1
ENSMUST00000055918.6
chemokine (C-C motif) receptor 2
chr2_+_132686931 0.27 ENSMUST00000061891.4
RIKEN cDNA 1110034G24 gene
chr6_-_136941494 0.27 ENSMUST00000111892.1
Rho, GDP dissociation inhibitor (GDI) beta
chr2_-_181693810 0.26 ENSMUST00000108776.1
ENSMUST00000108771.1
ENSMUST00000108779.1
ENSMUST00000108769.1
ENSMUST00000108772.1
ENSMUST00000002532.2
regulator of G-protein signaling 19
chr18_-_23038656 0.26 ENSMUST00000081423.6
nucleolar protein 4
chr16_-_22657165 0.26 ENSMUST00000089925.3
diacylglycerol kinase, gamma
chr2_-_145935014 0.26 ENSMUST00000001818.4
Crn, crooked neck-like 1 (Drosophila)
chr1_+_156036133 0.26 ENSMUST00000128941.1
torsin A interacting protein 2

Network of associatons between targets according to the STRING database.

First level regulatory network of Spib

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.5 2.7 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.5 2.4 GO:0002636 positive regulation of germinal center formation(GO:0002636)
0.4 1.3 GO:2000793 cell proliferation involved in heart valve development(GO:2000793)
0.4 2.2 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.3 1.3 GO:0001805 type III hypersensitivity(GO:0001802) regulation of type III hypersensitivity(GO:0001803) positive regulation of type III hypersensitivity(GO:0001805)
0.3 1.0 GO:0070947 neutrophil mediated killing of fungus(GO:0070947)
0.3 0.6 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.3 2.8 GO:0030886 negative regulation of myeloid dendritic cell activation(GO:0030886)
0.3 1.2 GO:0002540 leukotriene production involved in inflammatory response(GO:0002540)
0.3 0.9 GO:0071211 protein targeting to vacuole involved in autophagy(GO:0071211)
0.3 1.2 GO:0002434 immune complex clearance(GO:0002434)
0.3 1.1 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.3 0.8 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.2 0.7 GO:2000041 dermatome development(GO:0061054) regulation of dermatome development(GO:0061183) regulation of midbrain dopaminergic neuron differentiation(GO:1904956) regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
0.2 1.4 GO:0090383 phagosome acidification(GO:0090383)
0.2 0.7 GO:0032741 positive regulation of interleukin-18 production(GO:0032741) positive regulation of toll-like receptor 9 signaling pathway(GO:0034165)
0.2 1.0 GO:1905150 stress granule disassembly(GO:0035617) plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386) regulation of voltage-gated sodium channel activity(GO:1905150)
0.2 2.0 GO:0015691 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.2 1.2 GO:0072675 osteoclast fusion(GO:0072675)
0.2 1.2 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.2 0.6 GO:0045660 positive regulation of neutrophil differentiation(GO:0045660)
0.2 1.1 GO:0070944 neutrophil mediated cytotoxicity(GO:0070942) neutrophil mediated killing of symbiont cell(GO:0070943) neutrophil mediated killing of bacterium(GO:0070944) neutrophil mediated killing of gram-negative bacterium(GO:0070945)
0.2 0.9 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.2 0.5 GO:0001928 regulation of exocyst assembly(GO:0001928)
0.2 0.5 GO:0061033 secretion by lung epithelial cell involved in lung growth(GO:0061033)
0.2 1.0 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.2 0.8 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.2 0.6 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.1 1.0 GO:0001866 NK T cell proliferation(GO:0001866)
0.1 1.5 GO:0070862 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.1 1.3 GO:0035878 nail development(GO:0035878)
0.1 0.6 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.1 0.4 GO:0002865 negative regulation of acute inflammatory response to antigenic stimulus(GO:0002865)
0.1 0.4 GO:0031446 regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448)
0.1 0.6 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.1 0.7 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.1 0.3 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.1 0.7 GO:0039019 pronephric nephron development(GO:0039019)
0.1 0.3 GO:1903537 meiotic sister chromatid cohesion, centromeric(GO:0051754) meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
0.1 0.6 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.1 0.5 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.1 0.2 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.1 1.6 GO:0006465 signal peptide processing(GO:0006465)
0.1 0.6 GO:0046874 quinolinate metabolic process(GO:0046874)
0.1 0.3 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.1 1.2 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.1 0.9 GO:0071763 nuclear membrane organization(GO:0071763)
0.1 0.7 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.1 1.6 GO:0030238 male sex determination(GO:0030238)
0.1 0.7 GO:0045046 peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.1 1.0 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.1 0.7 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.1 2.5 GO:0018345 protein palmitoylation(GO:0018345)
0.1 0.3 GO:1904444 regulation of establishment of Sertoli cell barrier(GO:1904444)
0.1 0.3 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.1 0.4 GO:0003105 negative regulation of glomerular filtration(GO:0003105)
0.1 0.4 GO:0072092 ureteric bud invasion(GO:0072092)
0.1 1.0 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.1 0.5 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.1 0.3 GO:0014738 regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900)
0.1 0.5 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.1 0.4 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.1 1.8 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1 0.7 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.1 1.1 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.1 0.4 GO:0036438 maintenance of lens transparency(GO:0036438)
0.1 0.2 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.1 0.7 GO:1903301 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.1 0.4 GO:0060753 regulation of mast cell chemotaxis(GO:0060753)
0.1 0.3 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.1 0.4 GO:0010897 negative regulation of triglyceride catabolic process(GO:0010897)
0.1 0.7 GO:0071361 cellular response to ethanol(GO:0071361)
0.1 0.1 GO:0097195 pilomotor reflex(GO:0097195)
0.0 0.6 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.4 GO:0051013 microtubule severing(GO:0051013)
0.0 0.2 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.0 0.5 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.3 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.0 0.2 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.0 1.0 GO:0010884 positive regulation of lipid storage(GO:0010884)
0.0 0.2 GO:2000609 regulation of thyroid hormone generation(GO:2000609)
0.0 0.2 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.1 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0 0.2 GO:1901843 positive regulation of high voltage-gated calcium channel activity(GO:1901843)
0.0 0.3 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.0 0.3 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.0 0.2 GO:2001280 positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.0 0.1 GO:0016068 regulation of type I hypersensitivity(GO:0001810) positive regulation of type I hypersensitivity(GO:0001812) type I hypersensitivity(GO:0016068)
0.0 0.9 GO:0006903 vesicle targeting(GO:0006903)
0.0 0.1 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973) positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.0 0.1 GO:0045013 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.0 0.3 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.3 GO:0002710 negative regulation of T cell mediated immunity(GO:0002710)
0.0 0.3 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 0.1 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
0.0 0.3 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.0 0.6 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0 0.4 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.4 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.0 0.5 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.1 GO:0002277 myeloid dendritic cell activation involved in immune response(GO:0002277)
0.0 0.2 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.0 0.2 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.0 0.5 GO:0032933 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 0.2 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.0 0.1 GO:0043686 co-translational protein modification(GO:0043686)
0.0 0.3 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.7 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991)
0.0 0.7 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.3 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.7 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.1 GO:0010616 negative regulation of cardiac muscle adaptation(GO:0010616)
0.0 0.1 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.0 0.1 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.2 GO:0090400 stress-induced premature senescence(GO:0090400)
0.0 0.3 GO:0038092 nodal signaling pathway(GO:0038092)
0.0 0.1 GO:1900095 regulation of dosage compensation by inactivation of X chromosome(GO:1900095)
0.0 0.3 GO:0043586 tongue development(GO:0043586)
0.0 0.3 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.4 GO:0042036 negative regulation of cytokine biosynthetic process(GO:0042036)
0.0 0.4 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.2 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.2 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 0.4 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.1 GO:1902916 positive regulation of protein polyubiquitination(GO:1902916)
0.0 0.2 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.2 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.8 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.3 GO:0035641 locomotory exploration behavior(GO:0035641)
0.0 0.4 GO:0043551 regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.0 0.4 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.2 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.3 0.9 GO:0097637 platelet dense granule membrane(GO:0031088) intrinsic component of autophagosome membrane(GO:0097636) integral component of autophagosome membrane(GO:0097637)
0.2 0.7 GO:0036019 endolysosome(GO:0036019)
0.2 1.6 GO:0005787 signal peptidase complex(GO:0005787)
0.2 0.8 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.1 0.6 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.1 0.9 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 0.8 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.1 1.0 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 0.7 GO:0000835 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.1 0.4 GO:0031673 H zone(GO:0031673)
0.1 0.4 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.1 0.2 GO:0005588 collagen type V trimer(GO:0005588)
0.1 1.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 0.4 GO:0005826 actomyosin contractile ring(GO:0005826)
0.1 3.0 GO:0001772 immunological synapse(GO:0001772)
0.1 0.2 GO:0099631 postsynaptic endocytic zone cytoplasmic component(GO:0099631)
0.0 1.0 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.3 GO:0033263 CORVET complex(GO:0033263)
0.0 1.0 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.4 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.7 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.2 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.7 GO:0051286 cell tip(GO:0051286)
0.0 0.6 GO:0031143 pseudopodium(GO:0031143)
0.0 0.6 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.7 GO:0071564 npBAF complex(GO:0071564)
0.0 0.8 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.5 GO:0042581 specific granule(GO:0042581)
0.0 0.3 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.0 0.4 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.5 GO:0000145 exocyst(GO:0000145)
0.0 1.2 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 0.2 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.0 0.7 GO:0030904 retromer complex(GO:0030904)
0.0 0.2 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.1 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.1 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.3 GO:0000124 SAGA complex(GO:0000124)
0.0 2.0 GO:0016605 PML body(GO:0016605)
0.0 0.3 GO:0033176 proton-transporting V-type ATPase complex(GO:0033176)
0.0 0.2 GO:0031209 SCAR complex(GO:0031209)
0.0 0.0 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 0.3 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.0 0.1 GO:0030478 actin cap(GO:0030478)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.7 GO:0005152 interleukin-1, Type II receptor binding(GO:0005151) interleukin-1 receptor antagonist activity(GO:0005152) interleukin-1 Type I receptor antagonist activity(GO:0045352) interleukin-1 Type II receptor antagonist activity(GO:0045353)
0.4 2.2 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.4 1.7 GO:0016823 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.4 1.2 GO:0004051 arachidonate 5-lipoxygenase activity(GO:0004051)
0.3 0.7 GO:0019767 IgE receptor activity(GO:0019767)
0.3 1.5 GO:0019770 IgG receptor activity(GO:0019770)
0.3 1.0 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.2 0.7 GO:0071568 UFM1 transferase activity(GO:0071568)
0.2 0.6 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.2 0.6 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.2 1.0 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704) IkappaB kinase activity(GO:0008384)
0.2 0.7 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.2 1.2 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 1.0 GO:0099609 microtubule lateral binding(GO:0099609)
0.1 0.4 GO:0035717 chemokine (C-C motif) ligand 7 binding(GO:0035717)
0.1 1.0 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.1 0.9 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 0.3 GO:0004974 leukotriene receptor activity(GO:0004974)
0.1 0.7 GO:0045322 unmethylated CpG binding(GO:0045322)
0.1 0.7 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 0.4 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1 1.3 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.1 0.7 GO:0030911 TPR domain binding(GO:0030911)
0.1 2.5 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 0.7 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 0.7 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.1 0.5 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.1 1.3 GO:0050811 GABA receptor binding(GO:0050811)
0.1 2.2 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 0.5 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.1 0.9 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 0.6 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.1 2.4 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 0.3 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.1 1.8 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 0.4 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.3 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.7 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.5 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 1.0 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.5 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.7 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.9 GO:0005521 lamin binding(GO:0005521)
0.0 0.4 GO:0070739 protein-glutamic acid ligase activity(GO:0070739)
0.0 0.4 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 1.9 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.4 GO:0005338 nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.0 0.6 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.6 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.2 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
0.0 0.6 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 3.1 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 1.7 GO:0070888 E-box binding(GO:0070888)
0.0 1.1 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.6 GO:0019825 oxygen binding(GO:0019825)
0.0 0.8 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.2 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.7 GO:0015149 hexose transmembrane transporter activity(GO:0015149)
0.0 0.1 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.7 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.3 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.3 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.2 GO:0046790 virion binding(GO:0046790)
0.0 1.0 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.0 0.4 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.1 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.1 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.4 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.8 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.2 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.8 GO:0005109 frizzled binding(GO:0005109)
0.0 0.1 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.2 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.6 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.6 GO:0050699 WW domain binding(GO:0050699)
0.0 0.2 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 1.1 GO:0097110 scaffold protein binding(GO:0097110)
0.0 0.2 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.7 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 4.2 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.3 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.4 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.2 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 0.4 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.1 2.5 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 5.7 PID BCR 5PATHWAY BCR signaling pathway
0.1 2.9 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.7 PID IL5 PATHWAY IL5-mediated signaling events
0.0 1.8 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.7 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 1.3 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 1.5 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.8 PID IL23 PATHWAY IL23-mediated signaling events
0.0 1.0 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.6 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 1.5 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.5 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.4 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.2 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.7 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.3 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 4.2 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.5 PID TNF PATHWAY TNF receptor signaling pathway
0.0 1.1 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.1 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.7 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 1.0 PID P73PATHWAY p73 transcription factor network
0.0 0.6 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.4 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.2 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.1 2.2 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 1.6 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 0.8 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.1 2.0 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 0.7 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 1.3 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.1 3.7 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.1 1.3 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1 1.0 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.1 0.4 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.1 3.2 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1 0.7 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 2.6 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 0.6 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 1.1 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.0 1.0 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 1.5 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 1.5 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.8 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 1.0 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.7 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.5 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.5 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.4 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.8 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.0 0.4 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.3 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 1.2 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 1.3 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 1.2 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.2 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.3 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 0.1 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.2 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 1.5 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.0 0.3 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.3 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.8 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.5 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.6 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.7 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
0.0 1.5 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 0.3 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity