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12D miR HR13_24

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Results for Srf

Z-value: 1.39

Motif logo

Transcription factors associated with Srf

Gene Symbol Gene ID Gene Info
ENSMUSG00000015605.5 serum response factor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Srfmm10_v2_chr17_-_46556158_465561880.821.9e-03Click!

Activity profile of Srf motif

Sorted Z-values of Srf motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_+_14863495 4.03 ENSMUST00000029076.4
carbonic anhydrase 3
chr6_-_85513586 3.79 ENSMUST00000095759.3
early growth response 4
chr18_+_34861200 3.43 ENSMUST00000165033.1
early growth response 1
chr6_-_83536215 3.03 ENSMUST00000075161.5
actin, gamma 2, smooth muscle, enteric
chr1_-_43163891 2.86 ENSMUST00000008280.7
four and a half LIM domains 2
chr2_+_127336152 2.74 ENSMUST00000028846.6
dual specificity phosphatase 2
chr14_+_3652030 2.47 ENSMUST00000167430.1
predicted gene 3020
chr14_+_4334763 2.42 ENSMUST00000165466.1
RIKEN cDNA 2610042L04 gene
chr14_+_3412614 2.38 ENSMUST00000170123.1
predicted gene 10409
chr2_+_156775409 2.32 ENSMUST00000088552.6
myosin, light polypeptide 9, regulatory
chr14_+_4855576 2.30 ENSMUST00000166776.1
predicted gene 3264
chr14_+_3049285 2.22 ENSMUST00000166494.1
predicted gene 2897
chr14_-_6287250 2.15 ENSMUST00000170104.2
predicted gene 3411
chr14_+_4415448 2.04 ENSMUST00000168866.1
predicted gene 3164
chr14_-_7568566 1.93 ENSMUST00000163790.1
predicted gene 3558
chr14_-_7027449 1.82 ENSMUST00000170738.2
predicted gene 10406
chr14_+_3810074 1.56 ENSMUST00000170480.1
predicted gene 3002
chr14_-_5389049 1.44 ENSMUST00000177986.1
predicted gene 3500
chr11_-_73324616 1.40 ENSMUST00000021119.2
aspartoacylase
chr2_+_31759993 1.36 ENSMUST00000124089.1
c-abl oncogene 1, non-receptor tyrosine kinase
chr14_+_5501674 1.35 ENSMUST00000181562.1
predicted gene, 3488
chr10_-_120899067 1.27 ENSMUST00000092143.5
methionine sulfoxide reductase B3
chr3_+_68468162 1.19 ENSMUST00000182532.1
schwannomin interacting protein 1
chr11_-_12412136 1.18 ENSMUST00000174874.1
cordon-bleu WH2 repeat
chr12_+_86678685 1.12 ENSMUST00000021681.3
vasohibin 1
chr2_-_127521358 1.10 ENSMUST00000028850.8
ENSMUST00000103215.4
Kv channel interacting protein 3, calsenilin
chr10_-_111997204 1.05 ENSMUST00000074805.5
GLI pathogenesis-related 1 (glioma)
chr7_+_101896817 1.04 ENSMUST00000143835.1
anaphase prompoting complex C subunit 15
chr17_+_7925990 1.04 ENSMUST00000036370.7
T cell activation Rho GTPase activating protein
chr14_+_20929416 1.03 ENSMUST00000022369.7
vinculin
chr3_-_152266320 1.01 ENSMUST00000046045.8
nexilin
chr14_-_5741577 0.96 ENSMUST00000177556.1
predicted gene 3373
chr12_-_103355967 0.95 ENSMUST00000021617.7
ankyrin repeat and SOCS box-containing 2
chr4_-_132351636 0.89 ENSMUST00000105951.1
regulator of chromosome condensation 1
chr11_+_101330605 0.89 ENSMUST00000103105.3
amine oxidase, copper containing 3
chr16_+_57549232 0.88 ENSMUST00000159414.1
filamin A interacting protein 1-like
chr1_+_67123015 0.86 ENSMUST00000027144.7
carbamoyl-phosphate synthetase 1
chr12_+_85473883 0.85 ENSMUST00000021674.6
FBJ osteosarcoma oncogene
chr7_-_137314394 0.79 ENSMUST00000168203.1
ENSMUST00000106118.2
ENSMUST00000169486.2
ENSMUST00000033378.5
early B cell factor 3
chr11_-_94973447 0.71 ENSMUST00000100551.4
ENSMUST00000152042.1
sarcoglycan, alpha (dystrophin-associated glycoprotein)
chr11_+_101331069 0.68 ENSMUST00000017316.6
amine oxidase, copper containing 3
chr11_-_120731944 0.68 ENSMUST00000154565.1
ENSMUST00000026148.2
carbonyl reductase 2
chr9_+_75051977 0.67 ENSMUST00000170310.1
ENSMUST00000166549.1
cAMP-regulated phosphoprotein 19
chr2_+_125068118 0.65 ENSMUST00000070353.3
solute carrier family 24, member 5
chr2_+_154548888 0.64 ENSMUST00000045116.4
ENSMUST00000109709.3
RIKEN cDNA 1700003F12 gene
chr7_-_19310035 0.60 ENSMUST00000003640.2
FBJ osteosarcoma oncogene B
chr7_+_128246812 0.56 ENSMUST00000164710.1
ENSMUST00000070656.5
transforming growth factor beta 1 induced transcript 1
chr4_+_43957401 0.55 ENSMUST00000030202.7
GLI pathogenesis-related 2
chr15_-_76229492 0.53 ENSMUST00000074834.5
plectin
chr10_+_79988584 0.51 ENSMUST00000004784.4
ENSMUST00000105374.1
calponin 2
chr14_+_55575617 0.48 ENSMUST00000022826.5
fat storage-inducing transmembrane protein 1
chr11_+_33963013 0.48 ENSMUST00000020362.2
potassium large conductance calcium-activated channel, subfamily M, beta member 1
chr7_+_128246953 0.47 ENSMUST00000167965.1
transforming growth factor beta 1 induced transcript 1
chr7_+_101896340 0.47 ENSMUST00000035395.7
ENSMUST00000106973.1
ENSMUST00000144207.1
anaphase prompoting complex C subunit 15
chr6_+_113378113 0.46 ENSMUST00000171058.1
ENSMUST00000156898.1
actin related protein 2/3 complex, subunit 4
chr18_+_45268876 0.45 ENSMUST00000183850.1
ENSMUST00000066890.7
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chr1_+_63176818 0.44 ENSMUST00000129339.1
eukaryotic translation elongation factor 1 beta 2
chr15_-_77842133 0.44 ENSMUST00000016771.6
myosin, heavy polypeptide 9, non-muscle
chr3_-_57575907 0.42 ENSMUST00000120977.1
WW domain containing transcription regulator 1
chr12_-_110696289 0.42 ENSMUST00000021698.6
heat shock protein 90, alpha (cytosolic), class A member 1
chr12_-_110695860 0.42 ENSMUST00000149189.1
heat shock protein 90, alpha (cytosolic), class A member 1
chr12_-_80968075 0.42 ENSMUST00000095572.4
solute carrier family 10 (sodium/bile acid cotransporter family), member 1
chr10_+_67537861 0.42 ENSMUST00000048289.7
ENSMUST00000105438.2
ENSMUST00000130933.1
ENSMUST00000146986.1
early growth response 2
chr8_-_71381907 0.41 ENSMUST00000002466.8
nuclear receptor subfamily 2, group F, member 6
chr5_-_145191511 0.41 ENSMUST00000161845.1
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F2
chr12_-_110696248 0.39 ENSMUST00000124156.1
heat shock protein 90, alpha (cytosolic), class A member 1
chr3_-_95891938 0.38 ENSMUST00000036360.6
ENSMUST00000090476.3
cDNA sequence BC028528
chr4_+_43957678 0.38 ENSMUST00000107855.1
GLI pathogenesis-related 2
chr7_+_119896292 0.37 ENSMUST00000106517.1
LYR motif containing 1
chr3_+_90072641 0.37 ENSMUST00000121503.1
ENSMUST00000119570.1
ENSMUST00000062193.9
tropomyosin 3, gamma
chr13_+_109260481 0.34 ENSMUST00000153234.1
phosphodiesterase 4D, cAMP specific
chr10_+_4266323 0.33 ENSMUST00000045730.5
A kinase (PRKA) anchor protein (gravin) 12
chr15_-_10714612 0.31 ENSMUST00000169385.1
retinoic acid induced 14
chr9_-_66514567 0.30 ENSMUST00000056890.8
F-box and leucine-rich repeat protein 22
chr2_+_69380431 0.27 ENSMUST00000063690.3
dehydrogenase/reductase (SDR family) member 9
chr14_-_45529964 0.27 ENSMUST00000150660.1
fermitin family homolog 2 (Drosophila)
chr4_+_132351768 0.27 ENSMUST00000172202.1
predicted gene, 17300
chr7_+_19411086 0.27 ENSMUST00000003643.1
creatine kinase, muscle
chr3_-_95891929 0.26 ENSMUST00000171519.1
cDNA sequence BC028528
chr14_+_74732384 0.25 ENSMUST00000176957.1
esterase D/formylglutathione hydrolase
chr1_+_167618246 0.25 ENSMUST00000111380.1
retinoid X receptor gamma
chr1_+_78816909 0.24 ENSMUST00000057262.6
potassium voltage-gated channel, Isk-related subfamily, gene 4
chr7_-_105600103 0.23 ENSMUST00000033185.8
hemopexin
chr14_-_76010863 0.22 ENSMUST00000088922.4
general transcription factor IIF, polypeptide 2
chr16_-_4880284 0.21 ENSMUST00000037843.6
UBA-like domain containing 1
chr17_-_46153517 0.21 ENSMUST00000171172.1
MAD2L1 binding protein
chr11_-_120348475 0.20 ENSMUST00000062147.7
ENSMUST00000128055.1
actin, gamma, cytoplasmic 1
chr11_-_120348091 0.20 ENSMUST00000106215.4
actin, gamma, cytoplasmic 1
chr7_-_44997535 0.20 ENSMUST00000124232.1
ENSMUST00000003290.4
BCL2-like 12 (proline rich)
chr7_+_119895836 0.20 ENSMUST00000106518.1
ENSMUST00000054440.3
LYR motif containing 1
chrX_-_166518567 0.19 ENSMUST00000112187.1
transcription elongation factor A (SII) N-terminal and central domain containing
chr2_+_127208358 0.17 ENSMUST00000103220.3
small nuclear ribonucleoprotein 200 (U5)
chr19_+_5447692 0.17 ENSMUST00000025850.5
fos-like antigen 1
chr4_-_63403330 0.16 ENSMUST00000035724.4
AT-hook transcription factor
chr2_+_164940742 0.16 ENSMUST00000137626.1
matrix metallopeptidase 9
chr7_+_120677579 0.15 ENSMUST00000060175.6
cDNA sequence BC030336
chr1_-_33757711 0.15 ENSMUST00000044691.7
BCL2-associated athanogene 2
chr11_-_120348513 0.14 ENSMUST00000071555.6
actin, gamma, cytoplasmic 1
chr17_-_46556158 0.14 ENSMUST00000015749.5
serum response factor
chr2_+_164833841 0.14 ENSMUST00000152721.1
cathepsin A
chr7_+_19131686 0.13 ENSMUST00000165913.1
F-box protein 46
chr9_+_53537021 0.12 ENSMUST00000035850.7
nuclear protein in the AT region
chr7_-_119720742 0.11 ENSMUST00000033236.7
THUMP domain containing 1
chr1_+_180942325 0.10 ENSMUST00000161847.1
transmembrane protein 63a
chr15_-_36794498 0.09 ENSMUST00000110361.1
ENSMUST00000022894.7
ENSMUST00000110359.1
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr2_-_164833438 0.09 ENSMUST00000042775.4
neuralized-like 2 (Drosophila)
chr9_-_58313189 0.09 ENSMUST00000061799.8
lysyl oxidase-like 1
chr1_-_131097535 0.09 ENSMUST00000016672.4
MAP kinase-activated protein kinase 2
chr11_-_99493112 0.07 ENSMUST00000006969.7
keratin 23
chr1_+_38987806 0.07 ENSMUST00000027247.5
phosducin-like 3
chr19_+_25406661 0.07 ENSMUST00000146647.1
KN motif and ankyrin repeat domains 1
chr10_+_90576872 0.07 ENSMUST00000182550.1
ENSMUST00000099364.5
ankyrin repeat and sterile alpha motif domain containing 1B
chr2_-_13271268 0.05 ENSMUST00000137670.1
ENSMUST00000114791.2
Ras suppressor protein 1
chr5_-_112896350 0.04 ENSMUST00000086617.4
myosin XVIIIb
chr5_-_142905928 0.03 ENSMUST00000106216.2
actin, beta
chr14_-_45530118 0.02 ENSMUST00000045905.6
fermitin family homolog 2 (Drosophila)
chr2_+_20737306 0.00 ENSMUST00000114606.1
ENSMUST00000114608.1
enhancer trap locus 4

Network of associatons between targets according to the STRING database.

First level regulatory network of Srf

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.4 GO:0042222 interleukin-1 biosynthetic process(GO:0042222) positive regulation of metanephric glomerulus development(GO:0072300)
0.6 2.4 GO:0060025 regulation of synaptic activity(GO:0060025)
0.4 1.3 GO:1900275 negative regulation of phospholipase C activity(GO:1900275)
0.3 1.3 GO:0030091 protein repair(GO:0030091)
0.3 1.1 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.2 1.4 GO:0006083 acetate metabolic process(GO:0006083)
0.2 1.2 GO:0045585 regulation of cytotoxic T cell differentiation(GO:0045583) positive regulation of cytotoxic T cell differentiation(GO:0045585)
0.2 2.9 GO:0055015 ventricular cardiac muscle cell development(GO:0055015)
0.2 1.6 GO:0035902 response to immobilization stress(GO:0035902)
0.2 1.2 GO:0001757 somite specification(GO:0001757)
0.2 0.6 GO:0048022 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.1 1.0 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.1 0.4 GO:1903919 regulation of actin filament severing(GO:1903918) negative regulation of actin filament severing(GO:1903919)
0.1 0.9 GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.1 0.7 GO:0006116 NADH oxidation(GO:0006116)
0.1 0.4 GO:0021666 rhombomere formation(GO:0021594) rhombomere 3 formation(GO:0021660) rhombomere 5 morphogenesis(GO:0021664) rhombomere 5 formation(GO:0021666)
0.1 1.5 GO:0090266 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.1 4.0 GO:0006730 one-carbon metabolic process(GO:0006730)
0.1 0.9 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.1 0.5 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.1 0.3 GO:0046294 formaldehyde catabolic process(GO:0046294)
0.1 0.4 GO:0072257 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.1 0.5 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.1 0.2 GO:0015886 heme transport(GO:0015886)
0.1 1.0 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 1.2 GO:0001553 luteinization(GO:0001553)
0.0 0.5 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.9 GO:0035994 response to muscle stretch(GO:0035994)
0.0 0.5 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.3 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.3 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 2.9 GO:0070527 platelet aggregation(GO:0070527)
0.0 1.4 GO:0001706 endoderm formation(GO:0001706)
0.0 1.1 GO:0048266 behavioral response to pain(GO:0048266)
0.0 0.3 GO:1901844 regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.2 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.1 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.0 0.5 GO:0050765 negative regulation of phagocytosis(GO:0050765)
0.0 0.7 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 0.1 GO:1904715 negative regulation of chaperone-mediated autophagy(GO:1904715)
0.0 0.2 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.0 0.1 GO:0090168 Golgi reassembly(GO:0090168)
0.0 0.4 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.9 GO:0051290 protein heterotetramerization(GO:0051290)
0.0 0.4 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 0.2 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.0 0.1 GO:0044351 macropinocytosis(GO:0044351)
0.0 0.2 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 0.5 GO:0010718 positive regulation of epithelial to mesenchymal transition(GO:0010718)
0.0 0.5 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.3 GO:0033622 integrin activation(GO:0033622)
0.0 0.1 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.0 0.6 GO:0071277 cellular response to calcium ion(GO:0071277)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.2 GO:0097226 sperm mitochondrial sheath(GO:0097226)
0.1 1.2 GO:1990357 terminal web(GO:1990357)
0.1 0.9 GO:0035976 AP1 complex(GO:0035976)
0.1 0.9 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.1 2.9 GO:0031430 M band(GO:0031430)
0.1 0.7 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 0.4 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1 0.4 GO:0005826 actomyosin contractile ring(GO:0005826) myosin II filament(GO:0097513)
0.1 1.9 GO:0016460 myosin II complex(GO:0016460)
0.1 1.5 GO:0005680 anaphase-promoting complex(GO:0005680)
0.1 1.0 GO:0005916 fascia adherens(GO:0005916)
0.0 0.5 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.2 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.1 GO:0005927 muscle tendon junction(GO:0005927)
0.0 0.4 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.4 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.5 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.1 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.0 0.9 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.9 GO:0031941 filamentous actin(GO:0031941)
0.0 1.7 GO:0072562 blood microparticle(GO:0072562)
0.0 3.1 GO:0031965 nuclear membrane(GO:0031965)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0052596 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.5 3.4 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.5 1.4 GO:0019807 aspartoacylase activity(GO:0019807)
0.3 4.0 GO:0016151 nickel cation binding(GO:0016151)
0.3 0.9 GO:0004088 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.2 0.6 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.2 1.3 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.2 1.2 GO:0002135 CTP binding(GO:0002135)
0.2 0.7 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.1 0.9 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.1 1.0 GO:0048495 Roundabout binding(GO:0048495)
0.1 2.3 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 0.5 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.1 1.3 GO:0070097 delta-catenin binding(GO:0070097)
0.1 1.4 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 0.3 GO:0018738 S-formylglutathione hydrolase activity(GO:0018738)
0.1 1.0 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 0.4 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 0.3 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.1 0.2 GO:0015232 heme transporter activity(GO:0015232)
0.1 0.3 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.1 GO:0070878 primary miRNA binding(GO:0070878)
0.0 1.1 GO:0003785 actin monomer binding(GO:0003785)
0.0 1.6 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 2.3 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.4 GO:0043495 protein anchor(GO:0043495)
0.0 0.2 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.0 0.2 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.2 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.9 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.3 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.4 GO:0071837 HMG box domain binding(GO:0071837)
0.0 1.0 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.1 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 8.7 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 2.9 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 1.2 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 3.6 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 2.3 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 1.3 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.6 PID RHOA PATHWAY RhoA signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 6.8 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 1.2 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1 0.4 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 2.9 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.9 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 1.3 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 4.3 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.4 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.5 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.4 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.5 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.1 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 0.2 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.4 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.3 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions