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12D miR HR13_24

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Results for Stat4_Stat3_Stat5b

Z-value: 0.78

Motif logo

Transcription factors associated with Stat4_Stat3_Stat5b

Gene Symbol Gene ID Gene Info
ENSMUSG00000062939.5 signal transducer and activator of transcription 4
ENSMUSG00000004040.10 signal transducer and activator of transcription 3
ENSMUSG00000020919.5 signal transducer and activator of transcription 5B

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Stat3mm10_v2_chr11_-_100939357_100939456-0.794.0e-03Click!
Stat5bmm10_v2_chr11_-_100822525_100822576-0.643.3e-02Click!
Stat4mm10_v2_chr1_+_51987139_51987151-0.431.9e-01Click!

Activity profile of Stat4_Stat3_Stat5b motif

Sorted Z-values of Stat4_Stat3_Stat5b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr9_+_107296843 2.90 ENSMUST00000167072.1
cytokine inducible SH2-containing protein
chrX_-_108664891 2.34 ENSMUST00000178160.1
predicted gene 379
chr14_+_30886476 1.63 ENSMUST00000006703.6
ENSMUST00000078490.5
ENSMUST00000120269.2
inter alpha-trypsin inhibitor, heavy chain 4
chr9_+_107296682 1.32 ENSMUST00000168260.1
cytokine inducible SH2-containing protein
chr9_-_121792478 1.27 ENSMUST00000035110.4
hedgehog acyltransferase-like
chr6_+_78380700 1.27 ENSMUST00000101272.1
regenerating islet-derived 3 alpha
chr14_+_30886521 1.16 ENSMUST00000168782.1
inter alpha-trypsin inhibitor, heavy chain 4
chr15_-_75566608 1.12 ENSMUST00000163116.1
ENSMUST00000023241.5
lymphocyte antigen 6 complex, locus H
chr4_+_120666562 1.10 ENSMUST00000094814.4
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4
chr6_-_5496296 1.04 ENSMUST00000019721.4
pyruvate dehydrogenase kinase, isoenzyme 4
chr16_-_35871544 0.86 ENSMUST00000042665.8
poly (ADP-ribose) polymerase family, member 14
chr10_-_95417099 0.84 ENSMUST00000135822.1
suppressor of cytokine signaling 2
chr10_+_95417352 0.82 ENSMUST00000181781.1
RIKEN cDNA 5730420D15 gene
chr18_-_3281036 0.81 ENSMUST00000049942.6
ENSMUST00000139537.1
ENSMUST00000124747.1
cAMP responsive element modulator
chr1_+_134182404 0.80 ENSMUST00000153856.1
ENSMUST00000082060.3
ENSMUST00000133701.1
ENSMUST00000132873.1
chitinase 3-like 1
chr5_+_135994796 0.73 ENSMUST00000111142.2
ENSMUST00000111145.3
ENSMUST00000111144.1
ENSMUST00000005072.3
ENSMUST00000130345.1
deltex 2 homolog (Drosophila)
chr8_-_105326252 0.72 ENSMUST00000070508.7
leucine rich repeat containing 29
chr8_+_105269837 0.71 ENSMUST00000172525.1
ENSMUST00000174837.1
ENSMUST00000173859.1
heat shock transcription factor 4
chr15_-_75567176 0.71 ENSMUST00000156032.1
ENSMUST00000127095.1
lymphocyte antigen 6 complex, locus H
chr4_+_115088708 0.69 ENSMUST00000171877.1
ENSMUST00000177647.1
ENSMUST00000106548.2
ENSMUST00000030488.2
PDZK1 interacting protein 1
chr1_+_134182150 0.68 ENSMUST00000156873.1
chitinase 3-like 1
chr15_-_75566811 0.66 ENSMUST00000065417.8
lymphocyte antigen 6 complex, locus H
chr1_-_136234113 0.64 ENSMUST00000120339.1
ENSMUST00000048668.8
RIKEN cDNA 5730559C18 gene
chr10_-_127041513 0.64 ENSMUST00000116231.2
methyltransferase like 21B
chr4_+_150927918 0.62 ENSMUST00000139826.1
ENSMUST00000116257.1
tumor necrosis factor receptor superfamily, member 9
chr6_+_41521782 0.61 ENSMUST00000070380.4
protease, serine, 2
chr11_-_109722214 0.60 ENSMUST00000020938.7
family with sequence similarity 20, member A
chr17_+_29090969 0.59 ENSMUST00000119901.1
cyclin-dependent kinase inhibitor 1A (P21)
chr6_-_65144908 0.59 ENSMUST00000031982.4
hematopoietic prostaglandin D synthase
chr15_+_10223974 0.57 ENSMUST00000128450.1
ENSMUST00000148257.1
ENSMUST00000128921.1
prolactin receptor
chr11_+_100860447 0.55 ENSMUST00000107357.2
signal transducer and activator of transcription 5A
chr13_-_67755132 0.55 ENSMUST00000091520.6
zinc finger protein 85, related sequence 1
chr14_-_63245219 0.55 ENSMUST00000118022.1
ENSMUST00000067417.3
GATA binding protein 4
chr17_+_39846958 0.53 ENSMUST00000182010.1
predicted gene, 26924
chr10_-_127070254 0.52 ENSMUST00000060991.4
tetraspanin 31
chr15_+_102102926 0.52 ENSMUST00000169627.1
ENSMUST00000046144.9
tensin like C1 domain-containing phosphatase
chr11_+_120530688 0.52 ENSMUST00000026119.7
glucagon receptor
chr13_-_67755192 0.51 ENSMUST00000144183.1
zinc finger protein 85, related sequence 1
chr10_-_95416850 0.50 ENSMUST00000020215.9
suppressor of cytokine signaling 2
chr1_-_9298499 0.50 ENSMUST00000132064.1
syntrophin, gamma 1
chrX_+_139684980 0.49 ENSMUST00000096313.3
TBC1 domain family, member 8B
chr11_+_82035569 0.49 ENSMUST00000000193.5
chemokine (C-C motif) ligand 2
chr2_-_152830266 0.49 ENSMUST00000140436.1
BCL2-like 1
chr6_+_135198034 0.48 ENSMUST00000130612.1
RIKEN cDNA 8430419L09 gene
chr9_-_105960642 0.48 ENSMUST00000165165.2
collagen, type VI, alpha 5
chr2_-_66634952 0.47 ENSMUST00000100064.2
ENSMUST00000100063.2
sodium channel, voltage-gated, type IX, alpha
chr15_+_89076124 0.47 ENSMUST00000165690.1
TraB domain containing
chr4_-_47010781 0.46 ENSMUST00000135777.1
predicted gene 568
chr10_-_54075702 0.46 ENSMUST00000105470.1
mannosidase 1, alpha
chr7_-_109731708 0.46 ENSMUST00000035372.1
achaete-scute complex homolog 3 (Drosophila)
chr4_-_57916283 0.45 ENSMUST00000063816.5
RIKEN cDNA D630039A03 gene
chr7_-_30924169 0.45 ENSMUST00000074671.6
hepcidin antimicrobial peptide 2
chr10_-_20312239 0.44 ENSMUST00000092680.2
RIKEN cDNA 4933406P04 gene
chr12_-_103631404 0.43 ENSMUST00000121625.1
ENSMUST00000044231.5
serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
chr4_-_64046925 0.43 ENSMUST00000107377.3
tenascin C
chr11_-_82764303 0.42 ENSMUST00000021040.3
ENSMUST00000100722.4
chaperonin containing Tcp1, subunit 6b (zeta)
chr4_+_83417715 0.42 ENSMUST00000030206.3
ENSMUST00000071544.4
small nuclear RNA activating complex, polypeptide 3
chr11_+_78536393 0.41 ENSMUST00000050366.8
ENSMUST00000108275.1
intraflagellar transport 20
chr1_-_171437288 0.41 ENSMUST00000181499.1
predicted gene, 26641
chr6_-_34177048 0.41 ENSMUST00000019143.8
solute carrier family 35, member B4
chr2_-_66634653 0.41 ENSMUST00000164384.2
ENSMUST00000169900.1
sodium channel, voltage-gated, type IX, alpha
chr11_-_69695521 0.40 ENSMUST00000181261.1
tumor necrosis factor (ligand) superfamily, member 12
chr6_+_41354105 0.39 ENSMUST00000072103.5
trypsin 10
chr11_+_78536355 0.39 ENSMUST00000128788.1
intraflagellar transport 20
chr7_-_100856289 0.39 ENSMUST00000139604.1
RELT tumor necrosis factor receptor
chr2_-_30903255 0.39 ENSMUST00000102852.3
prostaglandin E synthase
chr9_-_95815389 0.38 ENSMUST00000119760.1
plastin 1 (I-isoform)
chr6_+_90619241 0.38 ENSMUST00000032177.8
solute carrier family 41, member 3
chr18_-_36726730 0.38 ENSMUST00000061829.6
CD14 antigen
chr7_+_24134148 0.38 ENSMUST00000056549.7
zinc finger protein 235
chr17_-_68004075 0.38 ENSMUST00000024840.5
Rho GTPase activating protein 28
chrX_+_73117047 0.38 ENSMUST00000088459.2
predicted gene 14685
chr7_-_143784500 0.37 ENSMUST00000054048.8
MAS-related GPR, member E
chr9_-_119339989 0.37 ENSMUST00000035092.6
myeloid differentiation primary response gene 88
chr11_-_69695802 0.37 ENSMUST00000108649.1
ENSMUST00000174159.1
ENSMUST00000181810.1
cDNA sequence BC096441
tumor necrosis factor (ligand) superfamily, member 12
chr5_-_24445166 0.36 ENSMUST00000115043.1
ENSMUST00000115041.1
Fas-activated serine/threonine kinase
chr17_+_34187545 0.36 ENSMUST00000170086.1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr5_+_14025305 0.35 ENSMUST00000073957.6
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr1_+_135818593 0.35 ENSMUST00000038760.8
ladinin
chr11_+_53519920 0.35 ENSMUST00000147912.1
septin 8
chr9_+_38718263 0.35 ENSMUST00000001544.5
ENSMUST00000118144.1
von Willebrand factor A domain containing 5A
chr15_-_78305603 0.35 ENSMUST00000096356.3
colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage)
chr17_-_57247632 0.35 ENSMUST00000005975.6
G protein-coupled receptor 108
chr11_+_53519725 0.34 ENSMUST00000108987.1
ENSMUST00000121334.1
ENSMUST00000117061.1
septin 8
chr15_+_100334929 0.34 ENSMUST00000075420.4
methyltransferase like 7A3
chr16_-_42340595 0.34 ENSMUST00000102817.4
growth associated protein 43
chr10_+_99443699 0.34 ENSMUST00000167243.1
glutamate decarboxylase 1, pseudogene
chr17_+_47436731 0.34 ENSMUST00000150819.2
expressed sequence AI661453
chr10_-_54075730 0.33 ENSMUST00000105469.1
ENSMUST00000003843.8
mannosidase 1, alpha
chr5_+_30466044 0.33 ENSMUST00000031078.3
ENSMUST00000114743.1
RIKEN cDNA 1700001C02 gene
chr5_-_24445254 0.32 ENSMUST00000030800.6
Fas-activated serine/threonine kinase
chr11_+_119307764 0.32 ENSMUST00000106250.1
caspase recruitment domain family, member 14
chr8_+_25720054 0.32 ENSMUST00000068916.8
ENSMUST00000139836.1
phosphatidic acid phosphatase type 2 domain containing 1B
chr1_+_110099295 0.32 ENSMUST00000134301.1
cadherin 7, type 2
chr11_+_53519871 0.31 ENSMUST00000120878.2
septin 8
chr5_+_102481546 0.31 ENSMUST00000112854.1
Rho GTPase activating protein 24
chr4_+_49059256 0.31 ENSMUST00000076670.2
RIKEN cDNA E130309F12 gene
chr4_+_130308595 0.31 ENSMUST00000070532.7
fatty acid binding protein 3, muscle and heart
chr15_+_100353149 0.30 ENSMUST00000075675.5
ENSMUST00000088142.5
ENSMUST00000176287.1
cDNA sequence AB099516
methyltransferase like 7A2
chr17_+_43667389 0.30 ENSMUST00000170988.1
cytochrome P450, family 39, subfamily a, polypeptide 1
chr1_-_169747634 0.30 ENSMUST00000027991.5
ENSMUST00000111357.1
regulator of G-protein signaling 4
chr16_-_22161450 0.30 ENSMUST00000115379.1
insulin-like growth factor 2 mRNA binding protein 2
chr17_+_35126316 0.30 ENSMUST00000061859.6
DNA segment, Chr 17, human D6S53E
chr9_+_21015960 0.29 ENSMUST00000086399.4
intercellular adhesion molecule 1
chr15_-_54920115 0.29 ENSMUST00000171545.1
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr13_+_67173156 0.29 ENSMUST00000021997.6
regulator of sex limited protein 1
chr17_+_47436615 0.29 ENSMUST00000037701.6
expressed sequence AI661453
chr17_+_34187789 0.29 ENSMUST00000041633.8
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr11_-_69695753 0.29 ENSMUST00000180946.1
tumor necrosis factor (ligand) superfamily, member 12
chr6_+_56017489 0.29 ENSMUST00000052827.4
protein phosphatase 1, regulatory subunit 17
chr11_+_115912001 0.28 ENSMUST00000132961.1
small integral membrane protein 6
chr4_-_134018829 0.28 ENSMUST00000051674.2
lin-28 homolog A (C. elegans)
chr16_-_24393588 0.28 ENSMUST00000181640.1
RIKEN cDNA 1110054M08 gene
chr6_+_48841476 0.28 ENSMUST00000101426.4
transmembrane protein 176A
chr6_-_124769548 0.28 ENSMUST00000149652.1
ENSMUST00000112476.1
ENSMUST00000004378.8
enolase 2, gamma neuronal
chr8_+_25532125 0.28 ENSMUST00000167764.1
fibroblast growth factor receptor 1
chr7_-_127051948 0.27 ENSMUST00000051122.5
zymogen granule protein 16
chr14_+_65970804 0.27 ENSMUST00000138191.1
clusterin
chr14_+_65970610 0.27 ENSMUST00000127387.1
clusterin
chr4_-_42168603 0.27 ENSMUST00000098121.3
predicted gene 13305
chr8_-_11478618 0.26 ENSMUST00000033900.5
RAB20, member RAS oncogene family
chr16_-_74411776 0.26 ENSMUST00000116586.2
roundabout homolog 2 (Drosophila)
chr5_+_123015010 0.26 ENSMUST00000121652.1
ENSMUST00000051016.4
ORAI calcium release-activated calcium modulator 1
chr6_+_122308684 0.26 ENSMUST00000007602.8
ENSMUST00000112610.1
mannose-6-phosphate receptor, cation dependent
chr19_+_4711153 0.26 ENSMUST00000008991.6
spectrin beta, non-erythrocytic 2
chr16_+_91647859 0.26 ENSMUST00000119368.1
ENSMUST00000114037.2
ENSMUST00000114036.2
ENSMUST00000122302.1
Son DNA binding protein
chr14_+_65971049 0.26 ENSMUST00000128539.1
clusterin
chr9_+_44326804 0.25 ENSMUST00000054708.3
dolichyl-phosphate (UDP-N-acetylglucosamine) acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)
chr7_-_30944017 0.25 ENSMUST00000062620.7
hepcidin antimicrobial peptide
chr15_+_76380492 0.25 ENSMUST00000096385.4
ENSMUST00000160728.1
ENSMUST00000162319.1
maestro heat-like repeat family member 1
chr1_+_11414089 0.25 ENSMUST00000048613.7
ENSMUST00000171690.2
ENSMUST00000137824.1
ENSMUST00000135014.1
ENSMUST00000179089.1
RIKEN cDNA A830018L16 gene
RIKEN cDNA A830018L16 gene
chr9_-_49486209 0.25 ENSMUST00000055096.4
tetratricopeptide repeat domain 12
chr2_-_155729359 0.25 ENSMUST00000040833.4
ER degradation enhancer, mannosidase alpha-like 2
chr16_-_74411292 0.25 ENSMUST00000117200.1
roundabout homolog 2 (Drosophila)
chr6_+_78405148 0.25 ENSMUST00000023906.2
regenerating islet-derived 2
chr10_-_68541842 0.24 ENSMUST00000020103.2
RIKEN cDNA 1700040L02 gene
chr15_+_89075996 0.24 ENSMUST00000081702.5
TraB domain containing
chr14_+_65971164 0.24 ENSMUST00000144619.1
clusterin
chr18_+_80256300 0.24 ENSMUST00000091798.3
ENSMUST00000140594.1
ENSMUST00000070135.7
PQ loop repeat containing 1
chr18_+_80256249 0.24 ENSMUST00000129043.1
PQ loop repeat containing 1
chr14_-_121915774 0.24 ENSMUST00000055475.7
G protein-coupled receptor 18
chr1_-_130729249 0.24 ENSMUST00000171479.1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
chr13_-_17694729 0.24 ENSMUST00000068545.4
RIKEN cDNA 5033411D12 gene
chr6_+_34780412 0.24 ENSMUST00000115016.1
ENSMUST00000115017.1
ATP/GTP binding protein-like 3
chr17_-_34187219 0.23 ENSMUST00000173831.1
proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)
chr17_+_35866056 0.23 ENSMUST00000122899.1
protein phosphatase 1, regulatory subunit 18
chr2_-_37359274 0.23 ENSMUST00000009174.8
phosducin-like
chr2_-_37359235 0.23 ENSMUST00000112940.1
phosducin-like
chr11_+_77765588 0.23 ENSMUST00000164315.1
myosin XVIIIA
chr9_-_21239310 0.23 ENSMUST00000164812.1
ENSMUST00000049567.4
kelch-like ECH-associated protein 1
chr17_+_26715644 0.23 ENSMUST00000062519.7
ENSMUST00000144221.1
ENSMUST00000142539.1
ENSMUST00000151681.1
CREB3 regulatory factor
chr14_+_61607455 0.23 ENSMUST00000051184.8
potassium channel regulator
chr1_+_136624901 0.23 ENSMUST00000047734.8
ENSMUST00000112046.1
zinc finger protein 281
chr9_-_44526397 0.22 ENSMUST00000062215.7
chemokine (C-X-C motif) receptor 5
chr6_+_135197977 0.22 ENSMUST00000111915.1
ENSMUST00000111916.1
RIKEN cDNA 8430419L09 gene
chr4_-_126202335 0.22 ENSMUST00000142125.1
ENSMUST00000106141.2
thyroid hormone receptor associated protein 3
chr15_+_100304782 0.22 ENSMUST00000067752.3
methyltransferase like 7A1
chr15_-_54919961 0.22 ENSMUST00000167541.2
ENSMUST00000041591.9
ENSMUST00000173516.1
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr10_+_42583787 0.22 ENSMUST00000105497.1
ENSMUST00000144806.1
osteopetrosis associated transmembrane protein 1
chr7_+_105554360 0.22 ENSMUST00000046983.8
sphingomyelin phosphodiesterase 1, acid lysosomal
chr5_+_7960445 0.22 ENSMUST00000115421.1
STEAP family member 4
chr2_-_37359196 0.22 ENSMUST00000147703.1
phosducin-like
chr3_-_85741389 0.22 ENSMUST00000094148.4
family with sequence similarity 160, member A1
chr5_+_102724971 0.22 ENSMUST00000112853.1
Rho GTPase activating protein 24
chr6_+_139736895 0.22 ENSMUST00000111868.3
phosphatidylinositol 3-kinase, C2 domain containing, gamma polypeptide
chr4_-_140617062 0.22 ENSMUST00000154979.1
Rho guanine nucleotide exchange factor (GEF) 10-like
chr11_+_21572221 0.22 ENSMUST00000020568.3
ENSMUST00000131135.1
WD repeat containing planar cell polarity effector
chr4_-_126325672 0.22 ENSMUST00000102616.1
tektin 2
chr13_+_112464070 0.21 ENSMUST00000183663.1
ENSMUST00000184311.1
ENSMUST00000183886.1
interleukin 6 signal transducer
chr15_+_99392948 0.21 ENSMUST00000161250.1
ENSMUST00000160635.1
ENSMUST00000161778.1
transmembrane BAX inhibitor motif containing 6
chr17_+_46681038 0.21 ENSMUST00000002845.6
male enhanced antigen 1
chr19_+_22448242 0.21 ENSMUST00000037901.6
transient receptor potential cation channel, subfamily M, member 3
chr4_+_136310936 0.21 ENSMUST00000131671.1
heterogeneous nuclear ribonucleoprotein R
chr1_-_135258449 0.21 ENSMUST00000003135.7
E74-like factor 3
chr1_+_146497614 0.21 ENSMUST00000132847.1
ENSMUST00000166814.1
bone morphogenetic protein/retinoic acid inducible neural specific 3
chr8_-_111338152 0.21 ENSMUST00000056157.7
ENSMUST00000120432.1
mixed lineage kinase domain-like
chrX_-_10216918 0.21 ENSMUST00000072393.2
ENSMUST00000044598.6
ENSMUST00000073392.4
ENSMUST00000115533.1
ENSMUST00000115532.1
retinitis pigmentosa GTPase regulator
chr11_-_51857624 0.21 ENSMUST00000020655.7
ENSMUST00000109090.1
PHD finger protein 15
chr2_+_164403194 0.21 ENSMUST00000017151.1
recombination signal binding protein for immunoglobulin kappa J region-like
chr6_+_91473695 0.21 ENSMUST00000032183.4
transmembrane protein 43
chr11_-_103208542 0.21 ENSMUST00000021323.4
ENSMUST00000107026.2
RIKEN cDNA 1700023F06 gene
chr13_+_96542602 0.21 ENSMUST00000179226.1
collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
chr14_+_33954020 0.21 ENSMUST00000035695.8
retinol binding protein 3, interstitial
chr13_-_67399738 0.20 ENSMUST00000181071.1
ENSMUST00000109732.1
zinc finger protein 429
chr15_+_99392882 0.20 ENSMUST00000023749.8
transmembrane BAX inhibitor motif containing 6
chr8_+_127447669 0.20 ENSMUST00000159511.1
par-3 (partitioning defective 3) homolog (C. elegans)
chr1_-_155146755 0.20 ENSMUST00000027744.8
major histocompatibility complex, class I-related
chr2_-_33371486 0.20 ENSMUST00000113165.1
Ral GEF with PH domain and SH3 binding motif 1
chr18_+_50030977 0.20 ENSMUST00000145726.1
ENSMUST00000128377.1
tumor necrosis factor, alpha-induced protein 8
chr14_+_118137101 0.20 ENSMUST00000022728.2
G protein-coupled receptor 180
chr8_-_111337793 0.20 ENSMUST00000145862.1
mixed lineage kinase domain-like
chr1_-_175692624 0.20 ENSMUST00000027809.7
opsin 3
chr16_+_38902305 0.19 ENSMUST00000023478.7
immunoglobulin superfamily, member 11
chr19_-_58455161 0.19 ENSMUST00000135730.1
ENSMUST00000152507.1
glial cell line derived neurotrophic factor family receptor alpha 1
chr17_-_27728889 0.19 ENSMUST00000167489.1
ENSMUST00000138970.1
ENSMUST00000114870.1
ENSMUST00000025054.2
SAM pointed domain containing ets transcription factor
chr10_-_109010955 0.19 ENSMUST00000105276.1
ENSMUST00000064054.7
synaptotagmin I
chr18_-_43737186 0.19 ENSMUST00000025381.2
serine peptidase inhibitor, Kazal type 3
chr11_-_99986593 0.19 ENSMUST00000105050.2
keratin associated protein 16-1
chr5_-_66150898 0.19 ENSMUST00000113725.1
ENSMUST00000094757.2
RNA binding motif protein 47
chr4_-_15149051 0.19 ENSMUST00000041606.7
N-terminal EF-hand calcium binding protein 1

Network of associatons between targets according to the STRING database.

First level regulatory network of Stat4_Stat3_Stat5b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.4 GO:1903059 regulation of protein lipidation(GO:1903059)
0.3 1.0 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.2 0.7 GO:1905204 negative regulation of connective tissue replacement(GO:1905204)
0.2 0.7 GO:1902605 heterotrimeric G-protein complex assembly(GO:1902605)
0.2 0.9 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.2 0.7 GO:0034760 negative regulation of iron ion transport(GO:0034757) negative regulation of iron ion transmembrane transport(GO:0034760)
0.2 1.0 GO:1902847 regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.2 0.5 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.2 0.5 GO:0002436 immune complex clearance by monocytes and macrophages(GO:0002436) monocyte homeostasis(GO:0035702) regulation of immune complex clearance by monocytes and macrophages(GO:0090264) positive regulation of immune complex clearance by monocytes and macrophages(GO:0090265)
0.2 0.6 GO:2001183 negative regulation of interleukin-12 secretion(GO:2001183)
0.1 0.6 GO:0060376 positive regulation of mast cell differentiation(GO:0060376)
0.1 0.4 GO:0090481 pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.1 0.8 GO:0038161 prolactin signaling pathway(GO:0038161)
0.1 0.6 GO:0046967 cytosol to ER transport(GO:0046967)
0.1 4.5 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.1 0.4 GO:0071725 response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.1 0.9 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
0.1 0.4 GO:0035621 ER to Golgi ceramide transport(GO:0035621) ceramide transport(GO:0035627)
0.1 0.5 GO:0046898 response to cycloheximide(GO:0046898)
0.1 0.6 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.1 1.3 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.1 0.4 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.1 0.3 GO:0001868 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
0.1 0.6 GO:0071493 cellular response to UV-B(GO:0071493)
0.1 0.1 GO:0002434 immune complex clearance(GO:0002434)
0.1 0.3 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.1 0.4 GO:1902896 terminal web assembly(GO:1902896)
0.1 0.4 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.1 0.3 GO:0021837 motogenic signaling involved in postnatal olfactory bulb interneuron migration(GO:0021837) positive regulation of mitotic cell cycle DNA replication(GO:1903465)
0.1 0.4 GO:0072566 chemokine (C-X-C motif) ligand 1 production(GO:0072566) regulation of chemokine (C-X-C motif) ligand 1 production(GO:2000338)
0.1 2.5 GO:1905145 acetylcholine receptor signaling pathway(GO:0095500) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.1 0.3 GO:0016198 axon choice point recognition(GO:0016198)
0.1 0.4 GO:0031438 regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.1 0.2 GO:1904154 trimming of terminal mannose on B branch(GO:0036509) positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.1 0.2 GO:0002304 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.1 0.3 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.1 0.5 GO:0033762 response to glucagon(GO:0033762)
0.1 0.5 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.1 2.8 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.1 0.2 GO:1902524 positive regulation of protein K48-linked ubiquitination(GO:1902524)
0.1 0.2 GO:0070104 negative regulation of interleukin-6-mediated signaling pathway(GO:0070104)
0.1 0.4 GO:0032485 regulation of Ral protein signal transduction(GO:0032485)
0.1 1.5 GO:0071378 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.1 1.1 GO:0006491 N-glycan processing(GO:0006491)
0.1 0.3 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.1 0.8 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.1 0.4 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.1 0.5 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.1 0.2 GO:1903028 regulation of opsonization(GO:1903027) positive regulation of opsonization(GO:1903028)
0.1 0.2 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.1 0.3 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.1 0.2 GO:2000793 cell proliferation involved in heart valve development(GO:2000793)
0.1 0.2 GO:1990859 cellular response to endothelin(GO:1990859)
0.0 0.6 GO:0070166 enamel mineralization(GO:0070166)
0.0 0.6 GO:0070431 nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423) nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070431)
0.0 0.3 GO:0002457 T cell antigen processing and presentation(GO:0002457) receptor-mediated virion attachment to host cell(GO:0046813)
0.0 0.1 GO:2000314 negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.0 0.4 GO:0009301 snRNA transcription(GO:0009301)
0.0 0.1 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.0 0.7 GO:0031000 response to caffeine(GO:0031000)
0.0 0.3 GO:0090383 phagosome acidification(GO:0090383)
0.0 0.3 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 0.2 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
0.0 0.1 GO:2000825 positive regulation of androgen receptor activity(GO:2000825)
0.0 0.1 GO:0045404 positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.0 0.3 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.0 0.1 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.0 0.2 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.0 0.1 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.0 0.1 GO:0033685 negative regulation of luteinizing hormone secretion(GO:0033685)
0.0 0.1 GO:0090285 negative regulation of protein glycosylation in Golgi(GO:0090285)
0.0 0.3 GO:0019348 dolichol metabolic process(GO:0019348)
0.0 0.1 GO:0010980 regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980) bile acid signaling pathway(GO:0038183)
0.0 0.3 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.2 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.2 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.0 0.2 GO:0003383 apical constriction(GO:0003383)
0.0 0.1 GO:1903972 regulation of macrophage colony-stimulating factor signaling pathway(GO:1902226) regulation of response to macrophage colony-stimulating factor(GO:1903969) regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903972)
0.0 0.1 GO:0060416 response to growth hormone(GO:0060416)
0.0 0.3 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.2 GO:0033600 negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.0 0.7 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.1 GO:0035585 calcium-mediated signaling using extracellular calcium source(GO:0035585)
0.0 0.1 GO:0046909 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.0 0.2 GO:0006685 sphingomyelin catabolic process(GO:0006685) termination of signal transduction(GO:0023021)
0.0 0.1 GO:0036016 response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016)
0.0 0.1 GO:0051325 interphase(GO:0051325) mitotic interphase(GO:0051329)
0.0 0.1 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.3 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.0 0.1 GO:0070829 heterochromatin maintenance(GO:0070829)
0.0 0.1 GO:1900738 psychomotor behavior(GO:0036343) positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.0 0.1 GO:0060424 foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492)
0.0 0.1 GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.0 0.1 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.0 0.2 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.3 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.1 GO:0045041 protein import into mitochondrial intermembrane space(GO:0045041)
0.0 0.2 GO:0015808 L-alanine transport(GO:0015808)
0.0 0.1 GO:1901679 nucleotide transmembrane transport(GO:1901679)
0.0 0.1 GO:0006624 vacuolar protein processing(GO:0006624)
0.0 0.2 GO:0086023 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883) adrenergic receptor signaling pathway involved in heart process(GO:0086023)
0.0 0.1 GO:0032385 positive regulation of intracellular lipid transport(GO:0032379) positive regulation of intracellular sterol transport(GO:0032382) positive regulation of intracellular cholesterol transport(GO:0032385) lipid hydroperoxide transport(GO:1901373)
0.0 0.2 GO:0097461 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.0 0.1 GO:0008594 photoreceptor cell morphogenesis(GO:0008594)
0.0 0.1 GO:0036233 glycine import(GO:0036233)
0.0 0.1 GO:2000680 regulation of rubidium ion transport(GO:2000680)
0.0 0.1 GO:0030242 pexophagy(GO:0030242)
0.0 0.1 GO:0035522 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.0 0.1 GO:0014738 regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900) negative regulation of interleukin-8 biosynthetic process(GO:0045415) positive regulation of core promoter binding(GO:1904798)
0.0 0.2 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.1 GO:0035712 T-helper 2 cell activation(GO:0035712) regulation of T-helper 2 cell activation(GO:2000569) positive regulation of T-helper 2 cell activation(GO:2000570)
0.0 0.1 GO:0030423 targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.0 0.1 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.2 GO:1903301 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.0 0.1 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.0 0.1 GO:0052203 modulation by symbiont of host molecular function(GO:0052055) modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
0.0 0.1 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.7 GO:0048266 behavioral response to pain(GO:0048266)
0.0 0.1 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.0 0.1 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.0 0.1 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.0 0.1 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 0.2 GO:0060576 intestinal epithelial cell development(GO:0060576)
0.0 0.1 GO:1901748 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.0 0.1 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.0 0.0 GO:1903659 negative regulation of NAD(P)H oxidase activity(GO:0033861) pancreatic stellate cell proliferation(GO:0072343) regulation of complement-dependent cytotoxicity(GO:1903659) negative regulation of complement-dependent cytotoxicity(GO:1903660) regulation of pancreatic stellate cell proliferation(GO:2000229)
0.0 0.1 GO:0071431 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.0 0.1 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.1 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.1 GO:0009992 cellular water homeostasis(GO:0009992)
0.0 0.2 GO:0060056 mammary gland involution(GO:0060056)
0.0 0.1 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.1 GO:0071318 cellular response to ATP(GO:0071318)
0.0 0.1 GO:0006517 protein deglycosylation(GO:0006517)
0.0 0.2 GO:0036120 cellular response to platelet-derived growth factor stimulus(GO:0036120)
0.0 0.1 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.0 0.5 GO:0070266 necroptotic process(GO:0070266)
0.0 0.3 GO:0001967 suckling behavior(GO:0001967)
0.0 0.3 GO:0046457 prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
0.0 0.2 GO:0036159 inner dynein arm assembly(GO:0036159)
0.0 0.3 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.0 0.0 GO:0072221 distal convoluted tubule development(GO:0072025) metanephric distal convoluted tubule development(GO:0072221) metanephric distal tubule development(GO:0072235)
0.0 0.1 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.0 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.1 GO:0034141 positive regulation of toll-like receptor 3 signaling pathway(GO:0034141) positive regulation of cell adhesion molecule production(GO:0060355) positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.0 0.4 GO:0061157 mRNA destabilization(GO:0061157)
0.0 0.1 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.0 0.3 GO:0032620 interleukin-17 production(GO:0032620)
0.0 0.2 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.2 GO:0016540 protein autoprocessing(GO:0016540)
0.0 0.1 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.0 0.1 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.0 0.7 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.0 0.2 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.0 0.1 GO:0006012 galactose metabolic process(GO:0006012)
0.0 0.1 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 0.2 GO:0007288 sperm axoneme assembly(GO:0007288)
0.0 0.3 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.0 0.1 GO:1900227 positive regulation of NLRP3 inflammasome complex assembly(GO:1900227)
0.0 0.2 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.0 0.1 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.0 0.1 GO:0015791 polyol transport(GO:0015791)
0.0 0.4 GO:0001953 negative regulation of cell-matrix adhesion(GO:0001953)
0.0 1.0 GO:0043627 response to estrogen(GO:0043627)
0.0 0.0 GO:0060729 replication fork protection(GO:0048478) intestinal epithelial structure maintenance(GO:0060729)
0.0 0.3 GO:0071470 cellular response to osmotic stress(GO:0071470)
0.0 0.1 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.1 GO:0045351 type I interferon biosynthetic process(GO:0045351)
0.0 0.0 GO:1904446 transepithelial water transport(GO:0035377) positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161) positive regulation of establishment of Sertoli cell barrier(GO:1904446) negative regulation of type B pancreatic cell development(GO:2000077)
0.0 0.3 GO:0044030 regulation of DNA methylation(GO:0044030)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:1902636 kinociliary basal body(GO:1902636)
0.2 0.6 GO:0070557 PCNA-p21 complex(GO:0070557)
0.2 0.5 GO:0044299 C-fiber(GO:0044299)
0.1 0.6 GO:0042825 TAP complex(GO:0042825)
0.1 1.0 GO:0097418 neurofibrillary tangle(GO:0097418)
0.1 0.2 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.1 0.4 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 0.2 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.0 0.4 GO:1990357 terminal web(GO:1990357)
0.0 0.2 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.5 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.3 GO:0008091 spectrin(GO:0008091)
0.0 0.4 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.1 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.0 0.6 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.1 GO:0036019 endolysosome(GO:0036019)
0.0 0.3 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.1 GO:0070939 Dsl1p complex(GO:0070939) RZZ complex(GO:1990423)
0.0 0.1 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.0 0.2 GO:0033269 internode region of axon(GO:0033269)
0.0 0.4 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.1 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 0.1 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.5 GO:0031527 filopodium membrane(GO:0031527)
0.0 0.1 GO:0031251 PAN complex(GO:0031251)
0.0 0.3 GO:0044754 autolysosome(GO:0044754)
0.0 0.3 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.4 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.1 GO:0001651 dense fibrillar component(GO:0001651)
0.0 0.2 GO:0042599 lamellar body(GO:0042599)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.5 GO:0030673 axolemma(GO:0030673)
0.0 0.1 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.8 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 2.0 GO:0072562 blood microparticle(GO:0072562)
0.0 0.1 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.0 0.2 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 2.5 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.1 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.1 GO:0005827 polar microtubule(GO:0005827)
0.0 0.2 GO:0016600 flotillin complex(GO:0016600)
0.0 0.8 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.2 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.1 GO:0001739 sex chromatin(GO:0001739)
0.0 0.3 GO:0045095 keratin filament(GO:0045095)
0.0 0.2 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.1 GO:0020003 symbiont-containing vacuole(GO:0020003)
0.0 0.2 GO:0031143 pseudopodium(GO:0031143)
0.0 0.2 GO:0031045 dense core granule(GO:0031045)
0.0 0.1 GO:1990909 Wnt signalosome(GO:1990909)
0.0 0.3 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.1 GO:0070578 RISC-loading complex(GO:0070578)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.5 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.3 1.4 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.3 1.0 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.2 1.0 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.2 0.6 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.2 0.5 GO:0004967 glucagon receptor activity(GO:0004967)
0.1 0.8 GO:0002046 opsin binding(GO:0002046)
0.1 0.6 GO:0046980 peptide antigen-transporting ATPase activity(GO:0015433) tapasin binding(GO:0046980)
0.1 2.8 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 1.0 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 0.6 GO:0004925 prolactin receptor activity(GO:0004925)
0.1 0.7 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.1 0.4 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.1 0.4 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.1 0.4 GO:0070976 TIR domain binding(GO:0070976)
0.1 0.5 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.1 0.2 GO:0004923 interleukin-6 receptor activity(GO:0004915) leukemia inhibitory factor receptor activity(GO:0004923) interleukin-6 binding(GO:0019981)
0.1 0.4 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.1 0.4 GO:0071723 lipopeptide binding(GO:0071723)
0.1 0.6 GO:0051434 BH3 domain binding(GO:0051434)
0.1 0.2 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280) L-tyrosine transmembrane transporter activity(GO:0005302)
0.1 0.3 GO:0016972 thiol oxidase activity(GO:0016972)
0.1 0.4 GO:0097001 ceramide binding(GO:0097001)
0.1 0.4 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1 0.5 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 0.9 GO:0070403 NAD+ binding(GO:0070403)
0.1 0.4 GO:0045545 syndecan binding(GO:0045545)
0.1 0.1 GO:0031750 D3 dopamine receptor binding(GO:0031750)
0.0 0.4 GO:0070538 oleic acid binding(GO:0070538)
0.0 0.5 GO:0005338 nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.0 0.2 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.1 GO:1902121 lithocholic acid binding(GO:1902121) D3 vitamins binding(GO:1902271)
0.0 0.1 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.0 1.0 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.3 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.3 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.0 0.1 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.0 0.3 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.3 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.4 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.1 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.0 0.1 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.0 0.1 GO:0031208 POZ domain binding(GO:0031208)
0.0 0.1 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.0 0.2 GO:0017116 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116)
0.0 0.3 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.3 GO:0050700 CARD domain binding(GO:0050700)
0.0 1.0 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.1 GO:0030350 iron-responsive element binding(GO:0030350)
0.0 0.3 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.2 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.1 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 0.2 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 0.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.1 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429)
0.0 3.1 GO:0019210 kinase inhibitor activity(GO:0019210)
0.0 0.6 GO:0031402 sodium ion binding(GO:0031402)
0.0 1.0 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.2 GO:0046790 virion binding(GO:0046790)
0.0 0.2 GO:0046977 TAP binding(GO:0046977)
0.0 0.3 GO:0042301 phosphate ion binding(GO:0042301)
0.0 0.2 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.3 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.3 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.4 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.3 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.1 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.0 0.1 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.0 0.2 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 1.0 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.1 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.0 0.2 GO:0016918 retinal binding(GO:0016918)
0.0 0.6 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.2 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 0.1 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.0 0.1 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.0 0.3 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.0 GO:0008158 hedgehog receptor activity(GO:0008158)
0.0 0.2 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0 0.2 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.0 GO:0004335 galactokinase activity(GO:0004335)
0.0 0.3 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.0 GO:0002060 purine nucleobase binding(GO:0002060)
0.0 0.2 GO:0070628 proteasome binding(GO:0070628)
0.0 0.1 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.1 GO:0050733 RS domain binding(GO:0050733)
0.0 0.2 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.1 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 0.1 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.0 0.1 GO:0070883 pre-miRNA binding(GO:0070883)
0.0 0.1 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.1 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.0 0.3 GO:0005537 mannose binding(GO:0005537)
0.0 0.2 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.1 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.0 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.1 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.3 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.3 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.1 GO:0008430 selenium binding(GO:0008430)
0.0 0.1 GO:0050897 cobalt ion binding(GO:0050897)
0.0 0.0 GO:0070513 death domain binding(GO:0070513)
0.0 0.1 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.1 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.0 0.0 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.0 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.0 0.2 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.0 GO:0004769 steroid delta-isomerase activity(GO:0004769)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 4.2 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.1 0.6 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.7 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.5 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.3 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 0.1 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 0.8 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.7 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.2 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 1.1 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.0 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.8 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.6 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 0.3 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.4 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.5 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 0.1 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.4 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.2 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 0.3 PID IL6 7 PATHWAY IL6-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 6.6 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.1 1.0 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 0.6 REACTOME DEFENSINS Genes involved in Defensins
0.1 0.3 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.6 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.4 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.4 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.3 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.3 REACTOME OPSINS Genes involved in Opsins
0.0 0.4 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.5 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.1 REACTOME INCRETIN SYNTHESIS SECRETION AND INACTIVATION Genes involved in Incretin Synthesis, Secretion, and Inactivation
0.0 0.4 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.5 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.2 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.7 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.3 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.5 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.7 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.2 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.4 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.8 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.0 0.1 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.7 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.4 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.2 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.5 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.2 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.1 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.1 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.0 0.7 REACTOME TRANS GOLGI NETWORK VESICLE BUDDING Genes involved in trans-Golgi Network Vesicle Budding
0.0 0.1 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.3 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis