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12D miR HR13_24

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Results for Hoxa4

Z-value: 0.77

Motif logo

Transcription factors associated with Hoxa4

Gene Symbol Gene ID Gene Info
ENSMUSG00000000942.10 homeobox A4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hoxa4mm10_v2_chr6_-_52191695_52191753-0.691.9e-02Click!

Activity profile of Hoxa4 motif

Sorted Z-values of Hoxa4 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_70563435 1.36 ENSMUST00000123330.1
glutamate decarboxylase 1
chr18_+_37489465 1.11 ENSMUST00000055949.2
protocadherin beta 18
chr3_+_115080965 1.10 ENSMUST00000051309.8
olfactomedin 3
chr2_+_170731807 1.06 ENSMUST00000029075.4
docking protein 5
chr15_+_10249560 1.04 ENSMUST00000134410.1
prolactin receptor
chr6_+_43265582 1.00 ENSMUST00000031750.7
Rho guanine nucleotide exchange factor (GEF) 5
chr2_+_90885860 1.00 ENSMUST00000111466.2
C1q and tumor necrosis factor related protein 4
chr19_-_42752710 0.98 ENSMUST00000076505.3
pyridine nucleotide-disulphide oxidoreductase domain 2
chr13_+_23555023 0.90 ENSMUST00000045301.6
histone cluster 1, H1d
chr12_+_69790288 0.89 ENSMUST00000021378.3
RIKEN cDNA 4930512B01 gene
chr16_+_22857845 0.87 ENSMUST00000004574.7
ENSMUST00000178320.1
ENSMUST00000166487.2
DnaJ (Hsp40) homolog, subfamily B, member 11
chr13_+_89540636 0.85 ENSMUST00000022108.7
hyaluronan and proteoglycan link protein 1
chr9_-_121792478 0.79 ENSMUST00000035110.4
hedgehog acyltransferase-like
chr7_-_100855403 0.76 ENSMUST00000156855.1
RELT tumor necrosis factor receptor
chr18_+_37447641 0.74 ENSMUST00000052387.3
protocadherin beta 14
chr6_+_5390387 0.72 ENSMUST00000183358.1
ankyrin repeat and SOCS box-containing 4
chrX_+_159840463 0.70 ENSMUST00000112451.1
ENSMUST00000112453.2
SH3-domain kinase binding protein 1
chr4_-_62519885 0.69 ENSMUST00000107444.1
ENSMUST00000030090.3
aminolevulinate, delta-, dehydratase
chr13_+_42680565 0.69 ENSMUST00000128646.1
phosphatase and actin regulator 1
chrX_-_38252398 0.67 ENSMUST00000089056.3
ENSMUST00000089054.4
ENSMUST00000066498.7
transmembrane protein 255A
chr18_+_76059458 0.65 ENSMUST00000167921.1
zinc finger and BTB domain containing 7C
chr15_-_34356421 0.65 ENSMUST00000179647.1
RIKEN cDNA 9430069I07 gene
chr13_-_102905740 0.63 ENSMUST00000167462.1
microtubule associated serine/threonine kinase family member 4
chr17_+_39846958 0.62 ENSMUST00000182010.1
predicted gene, 26924
chr13_-_102906046 0.59 ENSMUST00000171791.1
microtubule associated serine/threonine kinase family member 4
chr6_-_138426735 0.57 ENSMUST00000162932.1
LIM domain only 3
chr1_+_165301863 0.57 ENSMUST00000178700.1
G protein-coupled receptor 161
chr9_-_50555170 0.55 ENSMUST00000119103.1
beta-carotene oxygenase 2
chr1_+_109983737 0.54 ENSMUST00000172005.1
cadherin 7, type 2
chr14_-_108914237 0.53 ENSMUST00000100322.2
SLIT and NTRK-like family, member 1
chr1_-_130729249 0.52 ENSMUST00000171479.1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
chr13_+_58807884 0.51 ENSMUST00000079828.5
neurotrophic tyrosine kinase, receptor, type 2
chr14_+_44988192 0.49 ENSMUST00000046891.5
prostaglandin E receptor 2 (subtype EP2)
chr2_+_147187424 0.48 ENSMUST00000144411.1
RIKEN cDNA 6430503K07 gene
chr3_-_122619442 0.46 ENSMUST00000162947.1
formin binding protein 1-like
chr17_-_29078953 0.46 ENSMUST00000133221.1
tumor protein p53 pathway corepressor 1
chr19_-_57197556 0.46 ENSMUST00000099294.2
actin-binding LIM protein 1
chr7_+_90426312 0.44 ENSMUST00000061391.7
coiled-coil domain containing 89
chr7_+_51878967 0.43 ENSMUST00000051912.6
growth arrest specific 2
chr10_-_64090265 0.43 ENSMUST00000105439.1
leucine rich repeat transmembrane neuronal 3
chr12_+_59129757 0.43 ENSMUST00000069430.8
ENSMUST00000177370.1
CTAGE family, member 5
chr12_+_52516077 0.42 ENSMUST00000110725.1
Rho GTPase activating protein 5
chr12_+_55598917 0.42 ENSMUST00000051857.3
insulinoma-associated 2
chr16_+_17331371 0.41 ENSMUST00000023450.6
ENSMUST00000161034.1
serine (or cysteine) peptidase inhibitor, clade D, member 1
chr7_-_109731708 0.40 ENSMUST00000035372.1
achaete-scute complex homolog 3 (Drosophila)
chr6_-_52012476 0.40 ENSMUST00000078214.5
src family associated phosphoprotein 2
chr4_+_114821722 0.40 ENSMUST00000137570.1
predicted gene 12830
chr19_+_11965817 0.38 ENSMUST00000025590.9
oxysterol binding protein
chr7_+_51879041 0.38 ENSMUST00000107591.2
growth arrest specific 2
chr17_-_84187939 0.37 ENSMUST00000060366.6
zinc finger protein 36, C3H type-like 2
chr4_+_19280850 0.37 ENSMUST00000102999.1
cyclic nucleotide gated channel beta 3
chr19_-_57197435 0.37 ENSMUST00000111550.1
actin-binding LIM protein 1
chr12_+_59129720 0.36 ENSMUST00000175912.1
ENSMUST00000176892.1
CTAGE family, member 5
chr11_+_94328242 0.36 ENSMUST00000021227.5
ankyrin repeat domain 40
chr13_-_102958084 0.34 ENSMUST00000099202.3
ENSMUST00000172264.1
microtubule associated serine/threonine kinase family member 4
chr17_+_6007580 0.34 ENSMUST00000115784.1
ENSMUST00000115785.1
synaptojanin 2
chr11_+_94327984 0.34 ENSMUST00000107818.2
ENSMUST00000051221.6
ankyrin repeat domain 40
chr6_+_72304592 0.34 ENSMUST00000183018.1
surfactant associated protein B
chr19_-_57197377 0.33 ENSMUST00000111546.1
actin-binding LIM protein 1
chr10_-_24092320 0.33 ENSMUST00000092654.2
trace amine-associated receptor 8B
chr19_-_28967794 0.33 ENSMUST00000162110.1
RIKEN cDNA 4430402I18 gene
chr11_-_30268169 0.33 ENSMUST00000006629.7
spectrin beta, non-erythrocytic 1
chr16_-_22857514 0.32 ENSMUST00000004576.6
TBCC domain containing 1
chr2_+_4400958 0.32 ENSMUST00000075767.7
FERM domain containing 4A
chr6_-_92534855 0.32 ENSMUST00000113446.1
prickle homolog 2 (Drosophila)
chr5_+_137030275 0.31 ENSMUST00000041543.8
VGF nerve growth factor inducible
chr16_-_36990449 0.31 ENSMUST00000075869.6
F-box protein 40
chr19_-_57197496 0.30 ENSMUST00000111544.1
actin-binding LIM protein 1
chr6_+_77242644 0.29 ENSMUST00000159616.1
leucine rich repeat transmembrane neuronal 1
chr10_-_127121125 0.29 ENSMUST00000164259.1
ENSMUST00000080975.4
amplified in osteosarcoma
chrX_+_48623737 0.29 ENSMUST00000114936.1
solute carrier family 25 (mitochondrial carrier, brain), member 14
chr4_+_144893127 0.29 ENSMUST00000142808.1
dehydrogenase/reductase (SDR family) member 3
chr6_+_77242715 0.29 ENSMUST00000161677.1
leucine rich repeat transmembrane neuronal 1
chr13_-_55362782 0.29 ENSMUST00000021940.7
lectin, mannose-binding 2
chr8_+_46986913 0.28 ENSMUST00000039840.7
ENSMUST00000119686.1
ectonucleotide pyrophosphatase/phosphodiesterase 6
chr14_+_79515618 0.28 ENSMUST00000110835.1
E74-like factor 1
chr4_+_5724304 0.27 ENSMUST00000108380.1
family with sequence similarity 110, member B
chr3_+_134236483 0.27 ENSMUST00000181904.1
ENSMUST00000053048.9
CXXC finger 4
chr10_+_39612934 0.27 ENSMUST00000019987.6
TRAF3 interacting protein 2
chr4_-_134372529 0.27 ENSMUST00000030643.2
exostoses (multiple)-like 1
chr1_-_93478785 0.26 ENSMUST00000170883.1
high density lipoprotein (HDL) binding protein
chr8_-_67974567 0.26 ENSMUST00000098696.3
ENSMUST00000038959.9
ENSMUST00000093469.4
pleckstrin and Sec7 domain containing 3
chr3_+_41564880 0.26 ENSMUST00000168086.1
PHD finger protein 17
chr4_-_129378116 0.26 ENSMUST00000030610.2
zinc finger and BTB domain containing 8a
chr11_-_49114874 0.26 ENSMUST00000109201.1
olfactory receptor 1396
chr10_-_128525859 0.25 ENSMUST00000026427.6
extended synaptotagmin-like protein 1
chr10_-_93311073 0.25 ENSMUST00000008542.5
ELK3, member of ETS oncogene family
chrX_+_56454871 0.25 ENSMUST00000039374.2
ENSMUST00000101553.2
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B
chr11_-_116189542 0.25 ENSMUST00000148601.1
acyl-Coenzyme A oxidase 1, palmitoyl
chr18_+_37355271 0.25 ENSMUST00000051163.1
protocadherin beta 8
chr1_-_5070281 0.24 ENSMUST00000147158.1
ENSMUST00000118000.1
regulator of G-protein signaling 20
chr5_+_17574726 0.24 ENSMUST00000169603.1
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr17_+_45734506 0.24 ENSMUST00000180558.1
RIKEN cDNA F630040K05 gene
chr5_-_122614445 0.24 ENSMUST00000127220.1
ENSMUST00000031426.7
intraflagellar transport 81
chr6_+_56832059 0.23 ENSMUST00000031795.7
FK506 binding protein 9
chr4_-_3872105 0.23 ENSMUST00000105158.1
Moloney sarcoma oncogene
chr18_+_37435602 0.23 ENSMUST00000055495.5
protocadherin beta 12
chr6_-_41035501 0.22 ENSMUST00000031931.5
RIKEN cDNA 2210010C04 gene
chr18_+_37819543 0.22 ENSMUST00000055935.5
protocadherin gamma subfamily A, 9
chr16_+_4639941 0.22 ENSMUST00000038770.3
vasorin
chr10_+_127501707 0.22 ENSMUST00000035839.2
SH3 and cysteine rich domain 3
chr7_-_35056467 0.21 ENSMUST00000130491.1
CCAAT/enhancer binding protein (C/EBP), gamma
chr12_+_109546333 0.21 ENSMUST00000166636.2
maternally expressed 3
chr12_-_84361802 0.21 ENSMUST00000021659.1
ENSMUST00000065536.2
family with sequence similarity 161, member B
chrX_-_112698642 0.20 ENSMUST00000039887.3
premature ovarian failure 1B
chr18_-_37178493 0.20 ENSMUST00000181887.1
ENSMUST00000180516.1
predicted gene 10544
chr10_+_127501672 0.20 ENSMUST00000160019.1
ENSMUST00000160610.1
SH3 and cysteine rich domain 3
chr4_+_86575668 0.20 ENSMUST00000091064.6
Ras-related GTP binding A
chr12_+_10390756 0.19 ENSMUST00000020947.5
retinol dehydrogenase 14 (all-trans and 9-cis)
chr3_+_5218546 0.19 ENSMUST00000026284.6
zinc finger homeodomain 4
chr6_+_58833689 0.19 ENSMUST00000041401.8
hect domain and RLD 3
chr10_+_102158858 0.18 ENSMUST00000138522.1
ENSMUST00000163753.1
ENSMUST00000138016.1
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr1_-_110977366 0.18 ENSMUST00000094626.3
cadherin 19, type 2
chrX_+_20687954 0.18 ENSMUST00000115364.1
cyclin-dependent kinase 16
chr2_-_93849679 0.18 ENSMUST00000068513.4
ENSMUST00000041593.8
ENSMUST00000130077.1
1-aminocyclopropane-1-carboxylate synthase (non-functional)
chr1_+_172555932 0.18 ENSMUST00000061835.3
V-set and immunoglobulin domain containing 8
chr19_+_31868754 0.18 ENSMUST00000075838.5
APOBEC1 complementation factor
chr7_+_144838590 0.18 ENSMUST00000105898.1
fibroblast growth factor 3
chr17_+_80307396 0.17 ENSMUST00000068175.5
Rho guanine nucleotide exchange factor (GEF) 33
chr5_-_146220901 0.17 ENSMUST00000169407.2
ENSMUST00000161331.1
ENSMUST00000159074.2
ENSMUST00000067837.3
ring finger protein (C3H2C3 type) 6
chr14_+_27000362 0.16 ENSMUST00000035433.8
homeobox gene expressed in ES cells
chr6_-_56901870 0.16 ENSMUST00000101367.2
5'-nucleotidase, cytosolic III
chr10_+_127420334 0.16 ENSMUST00000171434.1
R3H domain containing 2
chr4_+_134068429 0.16 ENSMUST00000121391.1
absent in melanoma 1-like
chr11_+_83852135 0.16 ENSMUST00000146786.1
HNF1 homeobox B
chr9_+_75775355 0.16 ENSMUST00000012281.7
bone morphogenetic protein 5
chr6_+_72304625 0.16 ENSMUST00000070437.8
surfactant associated protein B
chr19_+_55894508 0.15 ENSMUST00000142291.1
transcription factor 7 like 2, T cell specific, HMG box
chr17_+_24470393 0.14 ENSMUST00000053024.6
phosphoglycolate phosphatase
chr6_+_106118924 0.14 ENSMUST00000079416.5
contactin 4
chr9_+_77636494 0.14 ENSMUST00000057781.7
kelch-like 31
chr2_-_6884940 0.14 ENSMUST00000183091.1
ENSMUST00000182851.1
CUGBP, Elav-like family member 2
chr12_+_109546409 0.14 ENSMUST00000143847.1
maternally expressed 3
chr1_+_74284930 0.14 ENSMUST00000113805.1
ENSMUST00000027370.6
ENSMUST00000087226.4
paroxysmal nonkinesiogenic dyskinesia
chr6_+_124916863 0.14 ENSMUST00000069553.2
RIKEN cDNA A230083G16 gene
chr9_-_49798729 0.14 ENSMUST00000166811.2
neural cell adhesion molecule 1
chr3_+_5218516 0.14 ENSMUST00000175866.1
zinc finger homeodomain 4
chr5_-_100373484 0.14 ENSMUST00000182433.1
Sec31 homolog A (S. cerevisiae)
chr1_-_86110672 0.14 ENSMUST00000155077.1
5-hydroxytryptamine (serotonin) receptor 2B
chr7_-_34654342 0.14 ENSMUST00000108069.1
potassium channel tetramerisation domain containing 15
chr18_-_15063560 0.14 ENSMUST00000168989.1
potassium channel tetramerisation domain containing 1
chr1_-_23909687 0.14 ENSMUST00000129254.1
small ArfGAP 1
chr2_+_70474923 0.13 ENSMUST00000100043.2
trans-acting transcription factor 5
chr9_-_65885024 0.13 ENSMUST00000122410.1
ENSMUST00000117083.1
thyroid hormone receptor interactor 4
chr17_+_43667389 0.13 ENSMUST00000170988.1
cytochrome P450, family 39, subfamily a, polypeptide 1
chr4_+_144892813 0.13 ENSMUST00000105744.1
ENSMUST00000171001.1
dehydrogenase/reductase (SDR family) member 3
chr18_+_86711520 0.13 ENSMUST00000122464.1
cerebellin 2 precursor protein
chr3_-_146781351 0.13 ENSMUST00000005164.7
protein kinase, cAMP dependent, catalytic, beta
chr7_+_135268579 0.13 ENSMUST00000097983.3
neuropeptide S
chr11_-_21572193 0.13 ENSMUST00000102874.4
malate dehydrogenase 1, NAD (soluble)
chr3_+_93442330 0.12 ENSMUST00000064257.5
trichohyalin
chr18_+_23752333 0.12 ENSMUST00000170802.1
ENSMUST00000155708.1
ENSMUST00000118826.2
microtubule-associated protein, RP/EB family, member 2
chr14_+_46832127 0.12 ENSMUST00000068532.8
cell growth regulator with ring finger domain 1
chr14_+_65266701 0.12 ENSMUST00000169656.1
F-box protein 16
chr3_-_88177671 0.12 ENSMUST00000181837.1
RIKEN cDNA 1700113A16 gene
chr7_+_34251038 0.12 ENSMUST00000105172.1
predicted gene 6096
chr11_-_121673103 0.12 ENSMUST00000067399.7
ENSMUST00000062654.7
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1
chr2_-_116065047 0.12 ENSMUST00000028639.6
ENSMUST00000102538.4
Meis homeobox 2
chr18_+_37307445 0.12 ENSMUST00000056712.2
protocadherin beta 4
chr1_+_180101144 0.11 ENSMUST00000133890.1
CDC42 binding protein kinase alpha
chr11_-_99322943 0.11 ENSMUST00000038004.2
keratin 25
chr7_+_64185459 0.11 ENSMUST00000177102.2
ENSMUST00000107519.1
ENSMUST00000137650.1
ENSMUST00000032737.5
ENSMUST00000107515.1
ENSMUST00000144996.1
transient receptor potential cation channel, subfamily M, member 1
chr9_-_49798905 0.11 ENSMUST00000114476.2
neural cell adhesion molecule 1
chr1_+_180111339 0.11 ENSMUST00000145181.1
CDC42 binding protein kinase alpha
chr2_+_93452796 0.11 ENSMUST00000099693.2
ENSMUST00000162565.1
ENSMUST00000163052.1
predicted gene 10804
chr5_+_105824511 0.10 ENSMUST00000055994.3
RIKEN cDNA D830014E11 gene
chr18_+_46925982 0.10 ENSMUST00000097580.1
ADP-ribosylation factor-like 14 effector protein-like
chr10_-_64090241 0.10 ENSMUST00000133588.1
leucine rich repeat transmembrane neuronal 3
chr7_-_142661858 0.10 ENSMUST00000145896.2
insulin-like growth factor 2
chr4_-_60222580 0.10 ENSMUST00000095058.4
ENSMUST00000163931.1
major urinary protein 8
chr6_+_29467718 0.10 ENSMUST00000004396.6
ATPase, H+ transporting, lysosomal V1 subunit F
chr2_-_6884975 0.10 ENSMUST00000114924.3
ENSMUST00000170438.1
ENSMUST00000114934.4
CUGBP, Elav-like family member 2
chr16_-_50432340 0.10 ENSMUST00000066037.6
ENSMUST00000089399.4
ENSMUST00000089404.3
ENSMUST00000114477.1
ENSMUST00000138166.1
bobby sox homolog (Drosophila)
chr1_+_130731963 0.10 ENSMUST00000039323.6
expressed sequence AA986860
chr6_+_97210689 0.09 ENSMUST00000044681.6
ADP-ribosylation factor-like 6 interacting protein 5
chr5_-_137531204 0.09 ENSMUST00000150063.2
guanine nucleotide binding protein (G protein), beta 2
chr11_+_57011945 0.09 ENSMUST00000094179.4
glutamate receptor, ionotropic, AMPA1 (alpha 1)
chrX_-_9469288 0.09 ENSMUST00000015484.3
cytochrome b-245, beta polypeptide
chr2_+_20737306 0.09 ENSMUST00000114606.1
ENSMUST00000114608.1
enhancer trap locus 4
chr12_-_57546121 0.09 ENSMUST00000044380.6
forkhead box A1
chr14_-_30353468 0.09 ENSMUST00000112249.1
calcium channel, voltage-dependent, L type, alpha 1D subunit
chr5_+_64812336 0.09 ENSMUST00000166409.1
Kruppel-like factor 3 (basic)
chr4_+_144893077 0.09 ENSMUST00000154208.1
dehydrogenase/reductase (SDR family) member 3
chr17_+_34592248 0.08 ENSMUST00000038149.6
pre B cell leukemia homeobox 2
chr1_-_74601345 0.08 ENSMUST00000136078.1
ENSMUST00000132081.1
ENSMUST00000113721.1
ENSMUST00000027357.5
ring finger protein 25
chrX_+_7697131 0.08 ENSMUST00000049896.6
G patch domain and KOW motifs
chr4_+_101550411 0.08 ENSMUST00000094953.4
ENSMUST00000106933.1
DnaJ (Hsp40) homolog, subfamily C, member 6
chr8_+_106059562 0.08 ENSMUST00000109308.1
nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 3
chr13_-_21832194 0.08 ENSMUST00000102979.1
histone cluster 1, H4n
chr11_-_30986326 0.08 ENSMUST00000020553.4
ENSMUST00000101394.4
ChaC, cation transport regulator 2
chr6_+_86527312 0.07 ENSMUST00000181928.1
RIKEN cDNA 1600020E01 gene
chrX_-_59166080 0.07 ENSMUST00000119306.1
fibroblast growth factor 13
chr2_+_109917639 0.07 ENSMUST00000046548.7
ENSMUST00000111037.2
leucine-rich repeat-containing G protein-coupled receptor 4
chr4_-_61674094 0.07 ENSMUST00000098040.3
major urinary protein 18
chr16_-_64786321 0.07 ENSMUST00000052588.4
zinc finger protein 654
chr8_-_60954726 0.07 ENSMUST00000110302.1
chloride channel 3
chr12_+_65075582 0.07 ENSMUST00000058889.4
Fanconi anemia, complementation group M
chr5_+_30814722 0.07 ENSMUST00000114724.1
microtubule-associated protein, RP/EB family, member 3
chr10_-_24101951 0.07 ENSMUST00000170267.1
trace amine-associated receptor 8C
chr4_+_101507947 0.07 ENSMUST00000149047.1
ENSMUST00000106929.3
DnaJ (Hsp40) homolog, subfamily C, member 6

Network of associatons between targets according to the STRING database.

First level regulatory network of Hoxa4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
0.2 1.4 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.2 1.0 GO:0038161 prolactin signaling pathway(GO:0038161)
0.2 0.8 GO:1903059 regulation of protein lipidation(GO:1903059)
0.1 0.9 GO:0016584 nucleosome positioning(GO:0016584)
0.1 0.2 GO:0001928 regulation of exocyst assembly(GO:0001928)
0.1 0.2 GO:1901994 meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.1 1.1 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.1 0.6 GO:0008300 isoprenoid catabolic process(GO:0008300)
0.1 0.7 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.1 0.3 GO:0051684 maintenance of centrosome location(GO:0051661) maintenance of Golgi location(GO:0051684)
0.1 0.5 GO:0031547 brain-derived neurotrophic factor receptor signaling pathway(GO:0031547) trans-synaptic signalling, modulating synaptic transmission(GO:0099550)
0.1 0.7 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.1 0.3 GO:0001830 trophectodermal cell fate commitment(GO:0001830)
0.0 0.1 GO:0006114 glycerol biosynthetic process(GO:0006114)
0.0 0.7 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.0 0.4 GO:1904628 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.0 0.1 GO:0007208 phospholipase C-activating serotonin receptor signaling pathway(GO:0007208)
0.0 1.0 GO:0016556 mRNA modification(GO:0016556)
0.0 0.1 GO:0010841 positive regulation of circadian sleep/wake cycle, wakefulness(GO:0010841)
0.0 0.3 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.2 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0 0.2 GO:0061296 regulation of pronephros size(GO:0035565) mesonephros morphogenesis(GO:0061206) mesonephric nephron development(GO:0061215) mesonephric nephron morphogenesis(GO:0061228) mesenchymal stem cell maintenance involved in mesonephric nephron morphogenesis(GO:0061235) regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061295) negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061296) mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:1901146)
0.0 0.2 GO:0060666 pulmonary myocardium development(GO:0003350) dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0 0.3 GO:0019695 choline metabolic process(GO:0019695)
0.0 0.4 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.0 0.2 GO:0021502 neural fold elevation formation(GO:0021502)
0.0 0.5 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.5 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.0 0.3 GO:0030916 otic vesicle formation(GO:0030916)
0.0 0.2 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 0.2 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.0 0.4 GO:1903301 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.0 0.2 GO:0051775 response to redox state(GO:0051775)
0.0 0.1 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743) alveolar secondary septum development(GO:0061144)
0.0 0.2 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.0 0.4 GO:0032570 response to progesterone(GO:0032570)
0.0 0.1 GO:0072318 clathrin coat disassembly(GO:0072318)
0.0 0.7 GO:0046685 response to arsenic-containing substance(GO:0046685)
0.0 0.2 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.3 GO:0043084 penile erection(GO:0043084)
0.0 0.1 GO:0097401 synaptic vesicle lumen acidification(GO:0097401)
0.0 1.2 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 0.1 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.0 0.6 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.0 0.1 GO:0002036 regulation of L-glutamate transport(GO:0002036)
0.0 0.4 GO:0044126 regulation of growth of symbiont in host(GO:0044126)
0.0 2.2 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.1 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.1 GO:0072282 metanephric nephron tubule morphogenesis(GO:0072282)
0.0 0.1 GO:1904528 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033) positive regulation of microtubule binding(GO:1904528)
0.0 0.2 GO:0044334 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) embryonic genitalia morphogenesis(GO:0030538) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) embryonic hindgut morphogenesis(GO:0048619)
0.0 0.3 GO:0048312 inositol phosphate dephosphorylation(GO:0046855) intracellular distribution of mitochondria(GO:0048312)
0.0 0.1 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.0 0.0 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.0 1.3 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.3 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.1 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.0 0.4 GO:0008340 determination of adult lifespan(GO:0008340)
0.0 0.4 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.0 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0 0.2 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.1 GO:0045196 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200) regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.0 0.3 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.0 0.1 GO:0046929 negative regulation of neurotransmitter secretion(GO:0046929)
0.0 0.2 GO:0042572 retinol metabolic process(GO:0042572)
0.0 0.2 GO:0045109 intermediate filament organization(GO:0045109)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.1 0.9 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.3 GO:0008091 spectrin(GO:0008091) cuticular plate(GO:0032437)
0.0 0.5 GO:0097208 alveolar lamellar body(GO:0097208)
0.0 0.2 GO:1990130 Iml1 complex(GO:1990130) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 1.4 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.1 GO:0035841 new growing cell tip(GO:0035841)
0.0 0.3 GO:0000836 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.0 0.2 GO:0045293 mRNA editing complex(GO:0045293)
0.0 0.3 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0 0.1 GO:0044308 axonal spine(GO:0044308)
0.0 0.2 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 0.9 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.9 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.4 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.3 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 0.3 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.1 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.5 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.3 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.2 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 1.6 GO:0042641 actomyosin(GO:0042641)
0.0 0.2 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.1 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.1 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0004925 prolactin receptor activity(GO:0004925)
0.2 1.4 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.1 0.3 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.1 0.5 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.1 0.4 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.1 0.5 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.1 0.5 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.1 0.3 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.1 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.0 0.4 GO:0004331 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 0.2 GO:0016401 palmitoyl-CoA oxidase activity(GO:0016401)
0.0 0.9 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.1 GO:0008967 phosphoglycolate phosphatase activity(GO:0008967)
0.0 0.3 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 0.3 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.4 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.3 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.0 0.1 GO:1904315 transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.2 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.2 GO:0008106 alcohol dehydrogenase (NADP+) activity(GO:0008106)
0.0 0.5 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.7 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 1.1 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.2 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.1 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.5 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.2 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.1 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.0 0.3 GO:0005537 mannose binding(GO:0005537)
0.0 0.1 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.1 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.3 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.2 GO:0030275 LRR domain binding(GO:0030275)
0.0 0.2 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.4 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.4 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.1 GO:0051378 G-protein coupled serotonin receptor activity(GO:0004993) serotonin binding(GO:0051378)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.0 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 1.1 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 1.3 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.4 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.8 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.3 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.6 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.6 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.1 0.9 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.1 1.5 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.1 1.0 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.5 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.7 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.8 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.4 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 1.0 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.7 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.1 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.6 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.3 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.1 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.2 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism