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12D miR HR13_24

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Results for En1

Z-value: 1.57

Motif logo

Transcription factors associated with En1

Gene Symbol Gene ID Gene Info
ENSMUSG00000058665.7 engrailed 1

Activity profile of En1 motif

Sorted Z-values of En1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr13_-_71963713 3.04 ENSMUST00000077337.8
Iroquois related homeobox 1 (Drosophila)
chr13_-_3945349 2.69 ENSMUST00000058610.7
urocortin 3
chr1_-_158814469 2.67 ENSMUST00000161589.2
pappalysin 2
chr12_-_119238794 2.49 ENSMUST00000026360.8
integrin beta 8
chr4_-_131672133 2.12 ENSMUST00000144212.1
predicted gene 12962
chr11_+_115154139 2.03 ENSMUST00000021076.5
RAB37, member of RAS oncogene family
chr7_-_101869012 1.91 ENSMUST00000123321.1
folate receptor 1 (adult)
chr7_-_101868667 1.73 ENSMUST00000150184.1
folate receptor 1 (adult)
chr9_+_46998931 1.69 ENSMUST00000178065.1
predicted gene 4791
chr1_+_171155512 1.66 ENSMUST00000111334.1
myelin protein zero
chr10_+_34483400 1.60 ENSMUST00000019913.7
ENSMUST00000170771.1
fyn-related kinase
chr7_+_30699783 1.57 ENSMUST00000013227.7
RIKEN cDNA 2200002J24 gene
chr3_+_141465564 1.38 ENSMUST00000106236.2
ENSMUST00000075282.3
unc-5 homolog C (C. elegans)
chr19_-_32061438 1.38 ENSMUST00000096119.4
N-acylsphingosine amidohydrolase 2
chr8_+_82863351 1.37 ENSMUST00000078525.5
ring finger protein 150
chr2_-_103283760 1.34 ENSMUST00000111174.1
ets homologous factor
chr15_-_75747922 1.31 ENSMUST00000062002.4
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein A (avian)
chr4_-_106799779 1.27 ENSMUST00000145061.1
ENSMUST00000102762.3
acyl-CoA thioesterase 11
chr3_-_113532288 1.27 ENSMUST00000132353.1
amylase 2a1
chr9_-_106891870 1.27 ENSMUST00000160503.1
ENSMUST00000159620.2
ENSMUST00000160978.1
mesencephalic astrocyte-derived neurotrophic factor
chr8_-_24948771 1.24 ENSMUST00000119720.1
ENSMUST00000121438.2
a disintegrin and metallopeptidase domain 32
chr2_+_90885860 1.23 ENSMUST00000111466.2
C1q and tumor necrosis factor related protein 4
chr15_+_85510812 1.22 ENSMUST00000079690.2
predicted pseudogene 4825
chr13_+_67833235 1.22 ENSMUST00000060609.7
predicted gene 10037
chr9_-_95815389 1.21 ENSMUST00000119760.1
plastin 1 (I-isoform)
chr3_-_117868821 1.18 ENSMUST00000167877.1
ENSMUST00000169812.1
sorting nexin 7
chr3_+_141465592 1.16 ENSMUST00000130636.1
unc-5 homolog C (C. elegans)
chr4_-_42168603 1.11 ENSMUST00000098121.3
predicted gene 13305
chr3_+_114904062 1.10 ENSMUST00000081752.6
olfactomedin 3
chr17_+_69969217 1.08 ENSMUST00000060072.5
discs, large (Drosophila) homolog-associated protein 1
chr11_+_114727384 1.06 ENSMUST00000069325.7
dynein, axonemal, intermediate chain 2
chr6_+_29859686 1.05 ENSMUST00000134438.1
S-adenosylhomocysteine hydrolase-like 2
chr3_-_145032765 1.05 ENSMUST00000029919.5
chloride channel calcium activated 3
chr9_-_56928350 1.02 ENSMUST00000050916.5
sorting nexin 33
chr10_-_118295038 1.01 ENSMUST00000163808.1
interleukin 10-related T cell-derived inducible factor beta
chr11_+_69991633 1.00 ENSMUST00000108592.1
gamma-aminobutyric acid receptor associated protein
chr3_-_75270073 0.99 ENSMUST00000039047.4
serine (or cysteine) peptidase inhibitor, clade I, member 2
chr9_-_106891401 0.99 ENSMUST00000069036.7
mesencephalic astrocyte-derived neurotrophic factor
chr4_+_102421518 0.99 ENSMUST00000106904.2
phosphodiesterase 4B, cAMP specific
chr2_-_93452679 0.98 ENSMUST00000111257.1
ENSMUST00000145553.1
CD82 antigen
chr6_+_70726430 0.94 ENSMUST00000103410.1
immunoglobulin kappa constant
chr11_+_93098404 0.93 ENSMUST00000107859.1
ENSMUST00000042943.6
ENSMUST00000107861.1
ENSMUST00000107858.2
carbonic anhydrase 10
chr2_+_120567687 0.92 ENSMUST00000028743.3
ENSMUST00000116437.1
ENSMUST00000153580.1
ENSMUST00000142278.1
synaptosomal-associated protein 23
chr4_-_129614254 0.91 ENSMUST00000106037.2
ENSMUST00000179209.1
doublecortin domain containing 2b
chr4_-_47010781 0.91 ENSMUST00000135777.1
predicted gene 568
chr5_-_88527841 0.90 ENSMUST00000087033.3
immunoglobulin joining chain
chr3_+_94693556 0.88 ENSMUST00000090848.3
ENSMUST00000173981.1
ENSMUST00000173849.1
ENSMUST00000174223.1
selenium binding protein 2
chr15_+_10177623 0.88 ENSMUST00000124470.1
prolactin receptor
chr11_-_59809774 0.87 ENSMUST00000047706.2
ENSMUST00000102697.3
folliculin
chr12_-_50649190 0.87 ENSMUST00000002765.7
protein kinase D1
chr14_+_103513328 0.84 ENSMUST00000095576.3
sciellin
chr17_+_34197715 0.83 ENSMUST00000173441.1
ENSMUST00000025196.8
proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7)
chr19_-_40994133 0.82 ENSMUST00000117695.1
B cell linker
chr3_+_89246397 0.82 ENSMUST00000168900.1
keratinocyte associated protein 2
chr7_-_112159034 0.82 ENSMUST00000033036.5
dickkopf homolog 3 (Xenopus laevis)
chr11_+_108682602 0.82 ENSMUST00000106718.3
ENSMUST00000106715.1
ENSMUST00000106724.3
centrosomal protein 112
chr5_+_23787691 0.77 ENSMUST00000030852.6
ENSMUST00000120869.1
ENSMUST00000117783.1
ENSMUST00000115113.2
RAD50 interactor 1
chr10_-_61273242 0.77 ENSMUST00000120336.1
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 14
chr16_+_17405981 0.76 ENSMUST00000023449.8
synaptosomal-associated protein 29
chr7_+_125707945 0.76 ENSMUST00000148701.1
RIKEN cDNA D430042O09 gene
chr16_+_4886100 0.75 ENSMUST00000070658.8
ENSMUST00000023159.8
mahogunin, ring finger 1
chr12_-_83921809 0.74 ENSMUST00000135962.1
ENSMUST00000155112.1
ENSMUST00000136848.1
ENSMUST00000126943.1
numb gene homolog (Drosophila)
chr9_+_72958785 0.73 ENSMUST00000098567.2
ENSMUST00000034734.8
dyslexia susceptibility 1 candidate 1 homolog (human)
chr4_-_129558387 0.73 ENSMUST00000067240.4
lymphocyte protein tyrosine kinase
chr5_-_120887582 0.72 ENSMUST00000086368.5
2'-5' oligoadenylate synthetase 1G
chr2_+_105130883 0.72 ENSMUST00000111098.1
ENSMUST00000111099.1
Wilms tumor 1 homolog
chrX_-_162643575 0.71 ENSMUST00000101102.1
RALBP1 associated Eps domain containing protein 2
chr7_+_27486910 0.71 ENSMUST00000008528.7
SERTA domain containing 1
chr3_+_89245952 0.70 ENSMUST00000040888.5
keratinocyte associated protein 2
chr13_-_56895737 0.70 ENSMUST00000022023.6
ENSMUST00000109871.1
transient receptor potential cation channel, subfamily C, member 7
chr14_-_51146757 0.69 ENSMUST00000080126.2
ribonuclease, RNase A family, 1 (pancreatic)
chr1_-_40085823 0.69 ENSMUST00000181756.1
predicted gene, 16894
chr5_+_110100414 0.69 ENSMUST00000141066.1
phosphatidylinositol-specific phospholipase C, X domain containing 1
chr6_+_142298419 0.69 ENSMUST00000041993.2
islet amyloid polypeptide
chr7_+_30169861 0.68 ENSMUST00000085668.4
predicted gene 5113
chr2_-_32847231 0.68 ENSMUST00000050000.9
syntaxin binding protein 1
chr4_-_111902754 0.67 ENSMUST00000102719.1
ENSMUST00000102721.1
solute carrier family 5 (sodium/glucose cotransporter), member 9
chr6_+_71282280 0.66 ENSMUST00000080949.7
lysine-rich coiled-coil 1
chr17_-_84682932 0.66 ENSMUST00000066175.3
ATP-binding cassette, sub-family G (WHITE), member 5
chr12_+_8012359 0.65 ENSMUST00000171239.1
apolipoprotein B
chr2_+_174450678 0.65 ENSMUST00000016399.5
tubulin, beta 1 class VI
chr1_+_105780693 0.65 ENSMUST00000027559.6
tumor necrosis factor receptor superfamily, member 11a
chr6_+_29859662 0.64 ENSMUST00000128927.2
S-adenosylhomocysteine hydrolase-like 2
chr3_+_107036156 0.64 ENSMUST00000052718.3
potassium voltage-gated channel, shaker-related subfamily, member 3
chr1_-_156036473 0.63 ENSMUST00000097527.3
ENSMUST00000027738.7
torsin A interacting protein 1
chr16_-_52454074 0.63 ENSMUST00000023312.7
activated leukocyte cell adhesion molecule
chr8_+_23153271 0.63 ENSMUST00000071588.6
NK6 homeobox 3
chr11_-_80779989 0.62 ENSMUST00000041065.7
ENSMUST00000070997.5
myosin ID
chr12_+_59131286 0.62 ENSMUST00000176464.1
ENSMUST00000170992.2
ENSMUST00000176322.1
CTAGE family, member 5
chr15_-_60824942 0.62 ENSMUST00000100635.3
family with sequence similarity 84, member B
chr9_-_103202113 0.61 ENSMUST00000035157.8
signal recognition particle receptor, B subunit
chr11_-_99986593 0.61 ENSMUST00000105050.2
keratin associated protein 16-1
chr2_+_120567652 0.61 ENSMUST00000110711.2
synaptosomal-associated protein 23
chr6_-_142278836 0.60 ENSMUST00000111825.3
solute carrier organic anion transporter family, member 1a5
chr5_-_87569023 0.60 ENSMUST00000113314.2
sulfotransferase family 1D, member 1
chr12_+_84069325 0.60 ENSMUST00000046422.4
ENSMUST00000072505.4
acyl-CoA thioesterase 5
chr1_+_60778743 0.60 ENSMUST00000130082.1
RIKEN cDNA 2310016D23 gene
chr6_+_124493101 0.59 ENSMUST00000049124.9
complement component 1, r subcomponent-like
chr6_+_87730869 0.58 ENSMUST00000159570.2
ENSMUST00000032132.8
EF hand and coiled-coil domain containing 1
chr18_-_15403680 0.56 ENSMUST00000079081.6
aquaporin 4
chr16_-_45953493 0.56 ENSMUST00000136405.1
pleckstrin homology-like domain, family B, member 2
chr10_+_112165676 0.56 ENSMUST00000170013.1
calcyphosphine 2
chr11_+_95010277 0.55 ENSMUST00000124735.1
sterile alpha motif domain containing 14
chr17_+_34914459 0.54 ENSMUST00000007249.8
solute carrier family 44, member 4
chr3_+_40950631 0.54 ENSMUST00000048490.6
La ribonucleoprotein domain family, member 1B
chr4_-_129227883 0.54 ENSMUST00000106051.1
expressed sequence C77080
chr1_+_57774600 0.54 ENSMUST00000167971.1
ENSMUST00000170139.1
ENSMUST00000171699.1
ENSMUST00000164302.1
spermatogenesis associated, serine-rich 2-like
chr17_-_33760306 0.54 ENSMUST00000173860.1
RAB11B, member RAS oncogene family
chr9_-_64341288 0.54 ENSMUST00000068367.7
DIS3 mitotic control homolog (S. cerevisiae)-like
chr10_-_75032528 0.54 ENSMUST00000159994.1
ENSMUST00000179546.1
ENSMUST00000160450.1
ENSMUST00000160072.1
ENSMUST00000009214.3
ENSMUST00000166088.1
rhabdoid tumor deletion region gene 1
chr14_+_44988192 0.53 ENSMUST00000046891.5
prostaglandin E receptor 2 (subtype EP2)
chr5_-_72752763 0.53 ENSMUST00000113604.3
TXK tyrosine kinase
chr1_+_109993982 0.53 ENSMUST00000027542.6
cadherin 7, type 2
chr13_-_110357136 0.53 ENSMUST00000058806.5
Grb2-binding adaptor, transmembrane
chr4_-_154025616 0.52 ENSMUST00000182191.1
ENSMUST00000146543.2
small integral membrane protein 1
chr10_+_127290774 0.51 ENSMUST00000026475.8
ENSMUST00000139091.1
DNA-damage inducible transcript 3
chr17_+_47649621 0.50 ENSMUST00000145314.1
ubiquitin specific peptidase 49
chr3_+_154711125 0.50 ENSMUST00000051862.6
RIKEN cDNA 4922501L14 gene
chr16_-_38800193 0.50 ENSMUST00000057767.4
uroplakin 1B
chr10_-_127311740 0.50 ENSMUST00000037290.5
ENSMUST00000171564.1
methionine-tRNA synthetase
chr16_-_45953565 0.49 ENSMUST00000134802.1
pleckstrin homology-like domain, family B, member 2
chr12_+_11438191 0.49 ENSMUST00000181268.1
RIKEN cDNA 4930511A02 gene
chr11_+_57645417 0.49 ENSMUST00000066987.7
ENSMUST00000108846.1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 10
chr1_-_13660476 0.49 ENSMUST00000027071.5
lactamase, beta 2
chr6_+_29859374 0.49 ENSMUST00000115238.3
S-adenosylhomocysteine hydrolase-like 2
chr19_+_60144682 0.48 ENSMUST00000065383.4
RIKEN cDNA E330013P04 gene
chr9_+_56994932 0.48 ENSMUST00000034832.6
protein tyrosine phosphatase, non-receptor type 9
chr7_+_140218258 0.48 ENSMUST00000084460.6
CD163 molecule-like 1
chr3_-_81975742 0.48 ENSMUST00000029645.8
tryptophan 2,3-dioxygenase
chr11_-_94507337 0.47 ENSMUST00000040692.8
MYCBP associated protein
chr16_-_45844303 0.46 ENSMUST00000036355.6
pleckstrin homology-like domain, family B, member 2
chr13_+_3924686 0.46 ENSMUST00000021639.6
tubulin, alpha-like 3
chr1_+_88211956 0.46 ENSMUST00000073049.6
UDP glucuronosyltransferase 1 family, polypeptide A1
chr2_+_25456830 0.45 ENSMUST00000114265.2
ENSMUST00000102918.2
chloride intracellular channel 3
chr6_-_137571007 0.45 ENSMUST00000100841.2
epidermal growth factor receptor pathway substrate 8
chr16_-_88056176 0.45 ENSMUST00000072256.5
ENSMUST00000023652.8
ENSMUST00000114137.1
glutamate receptor, ionotropic, kainate 1
chrX_-_6320717 0.45 ENSMUST00000024049.7
bone morphogenetic protein 15
chr10_+_118141787 0.45 ENSMUST00000163238.1
ENSMUST00000020437.5
ENSMUST00000164077.1
ENSMUST00000169817.1
transformed mouse 3T3 cell double minute 1
chr4_+_43632185 0.45 ENSMUST00000107874.2
natriuretic peptide receptor 2
chr1_-_52953179 0.44 ENSMUST00000114492.1
RIKEN cDNA 1700019D03 gene
chr15_+_102028216 0.44 ENSMUST00000023803.6
keratin 18
chr11_-_79504078 0.44 ENSMUST00000164465.2
oligodendrocyte myelin glycoprotein
chr7_+_43824519 0.44 ENSMUST00000107966.3
ENSMUST00000177514.1
kallikrein related-peptidase 6
chr5_-_120907510 0.44 ENSMUST00000080322.7
2'-5' oligoadenylate synthetase 1A
chr9_+_122888471 0.43 ENSMUST00000063980.6
zinc finger with KRAB and SCAN domains 7
chr7_+_43824493 0.43 ENSMUST00000107968.3
kallikrein related-peptidase 6
chrX_-_21089229 0.43 ENSMUST00000040667.6
zinc finger protein 300
chr17_-_33760451 0.43 ENSMUST00000057373.7
RAB11B, member RAS oncogene family
chr16_+_20548577 0.43 ENSMUST00000003319.5
ATP-binding cassette, sub-family F (GCN20), member 3
chr1_+_57774842 0.43 ENSMUST00000167085.1
spermatogenesis associated, serine-rich 2-like
chr1_+_151571481 0.43 ENSMUST00000111875.1
family with sequence similarity 129, member A
chr15_-_85581809 0.42 ENSMUST00000023015.7
wingless-related MMTV integration site 7B
chrX_+_145119501 0.42 ENSMUST00000096301.4
zinc finger, CCHC domain containing 16
chr4_-_125127817 0.42 ENSMUST00000036188.7
zinc finger CCCH type containing 12A
chr14_-_20618339 0.41 ENSMUST00000035340.7
ubiquitin specific peptidase 54
chr11_+_72314438 0.41 ENSMUST00000108504.1
F-box protein 39
chr9_+_44326804 0.41 ENSMUST00000054708.3
dolichyl-phosphate (UDP-N-acetylglucosamine) acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)
chr6_-_87809757 0.41 ENSMUST00000032134.7
RAB43, member RAS oncogene family
chr12_+_73997749 0.41 ENSMUST00000110451.2
synaptotagmin XVI
chr16_-_64771146 0.40 ENSMUST00000076991.6
RIKEN cDNA 4930453N24 gene
chr18_-_35662180 0.40 ENSMUST00000025209.4
ENSMUST00000096573.2
spermatogenesis associated 24
chr11_-_69369377 0.40 ENSMUST00000092971.6
ENSMUST00000108661.1
chromodomain helicase DNA binding protein 3
chr8_+_123212857 0.40 ENSMUST00000060133.6
spermatogenesis associated 33
chr17_-_56290499 0.40 ENSMUST00000019726.6
perilipin 3
chr11_+_103133303 0.39 ENSMUST00000107037.1
hexamethylene bis-acetamide inducible 2
chr16_-_43979050 0.39 ENSMUST00000165648.1
ENSMUST00000036321.7
zinc finger, DHHC domain containing 23
chr10_-_82285278 0.39 ENSMUST00000171401.1
RIKEN cDNA 4932415D10 gene
chr4_-_49383576 0.39 ENSMUST00000107698.1
acyl-coenzyme A amino acid N-acyltransferase 2
chr15_-_75888754 0.39 ENSMUST00000184858.1
maestro heat-like repeat family member 6
chr15_+_102407144 0.38 ENSMUST00000169619.1
trans-acting transcription factor 1
chr11_+_101552188 0.38 ENSMUST00000147239.1
neighbor of Brca1 gene 1
chr2_+_4017727 0.38 ENSMUST00000177457.1
FERM domain containing 4A
chr14_-_79223876 0.38 ENSMUST00000040802.4
zinc finger protein 957
chr2_+_172393794 0.38 ENSMUST00000099061.2
ENSMUST00000103073.2
Cas scaffolding protein family member 4
chr7_+_75455534 0.37 ENSMUST00000147005.1
ENSMUST00000166315.1
A kinase (PRKA) anchor protein 13
chr1_+_88138364 0.37 ENSMUST00000014263.4
UDP glucuronosyltransferase 1 family, polypeptide A6A
chr11_+_101552135 0.37 ENSMUST00000103099.1
neighbor of Brca1 gene 1
chr11_-_72796028 0.37 ENSMUST00000156294.1
cytochrome b5 domain containing 2
chr9_-_64341145 0.37 ENSMUST00000120760.1
ENSMUST00000168844.2
DIS3 mitotic control homolog (S. cerevisiae)-like
chr2_-_26140468 0.36 ENSMUST00000133808.1
RIKEN cDNA C330006A16 gene
chr16_-_13903015 0.36 ENSMUST00000115804.2
pyridoxal-dependent decarboxylase domain containing 1
chr2_-_167062981 0.36 ENSMUST00000048988.7
zinc finger, NFX1-type containing 1
chrX_+_139563316 0.36 ENSMUST00000113027.1
ring finger protein 128
chr17_-_42611313 0.36 ENSMUST00000068355.6
opsin 5
chr16_-_20730544 0.36 ENSMUST00000076422.5
thrombopoietin
chr13_+_22035821 0.36 ENSMUST00000110455.2
histone cluster 1, H2bk
chr6_-_3968357 0.36 ENSMUST00000031674.8
tissue factor pathway inhibitor 2
chr9_+_72438534 0.36 ENSMUST00000034746.8
meiosis-specific nuclear structural protein 1
chr17_-_34287770 0.35 ENSMUST00000174751.1
ENSMUST00000040655.6
histocompatibility 2, class II antigen A, alpha
chr16_-_26371828 0.35 ENSMUST00000023154.2
claudin 1
chr1_+_24177610 0.35 ENSMUST00000054588.8
collagen, type IX, alpha 1
chr3_+_93442330 0.35 ENSMUST00000064257.5
trichohyalin
chr13_+_40859768 0.35 ENSMUST00000110191.2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme
chr9_-_58202281 0.35 ENSMUST00000163897.1
immunoglobulin superfamily containing leucine-rich repeat 2
chr1_+_88134786 0.35 ENSMUST00000113134.1
ENSMUST00000140092.1
UDP glucuronosyltransferase 1 family, polypeptide A6A
chr14_+_55559993 0.35 ENSMUST00000117236.1
DDB1 and CUL4 associated factor 11
chr11_-_116828000 0.35 ENSMUST00000047715.5
ENSMUST00000021170.2
matrix-remodelling associated 7
chr3_+_55140033 0.35 ENSMUST00000118963.2
ENSMUST00000061099.7
ENSMUST00000153009.1
coiled-coil domain containing 169
chr11_+_67586520 0.34 ENSMUST00000108682.2
growth arrest specific 7
chr15_+_66670749 0.34 ENSMUST00000065916.7
thyroglobulin

Network of associatons between targets according to the STRING database.

First level regulatory network of En1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.0 GO:0072272 proximal/distal pattern formation involved in metanephric nephron development(GO:0072272)
0.8 2.3 GO:0002014 vasoconstriction of artery involved in ischemic response to lowering of systemic arterial blood pressure(GO:0002014)
0.4 3.6 GO:0003147 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713) cellular response to folic acid(GO:0071231)
0.3 2.5 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.3 1.2 GO:1902896 terminal web assembly(GO:1902896)
0.3 0.9 GO:0045796 negative regulation of intestinal phytosterol absorption(GO:0010949) negative regulation of intestinal cholesterol absorption(GO:0045796) intestinal phytosterol absorption(GO:0060752) negative regulation of intestinal lipid absorption(GO:1904730)
0.3 0.9 GO:1901856 negative regulation of cellular respiration(GO:1901856)
0.3 0.9 GO:0045872 positive regulation of rhodopsin gene expression(GO:0045872)
0.3 2.2 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.3 0.8 GO:0072425 signal transduction involved in G2 DNA damage checkpoint(GO:0072425) signal transduction involved in mitotic G2 DNA damage checkpoint(GO:0072434)
0.2 0.7 GO:0030862 neuroblast division in subventricular zone(GO:0021849) positive regulation of polarized epithelial cell differentiation(GO:0030862)
0.2 1.0 GO:0045054 constitutive secretory pathway(GO:0045054)
0.2 0.7 GO:2001076 negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302) regulation of metanephric ureteric bud development(GO:2001074) positive regulation of metanephric ureteric bud development(GO:2001076)
0.2 0.6 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.2 1.5 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.2 0.8 GO:0016240 autophagosome docking(GO:0016240)
0.2 0.5 GO:1900620 acetylcholine biosynthetic process(GO:0008292) acetate ester biosynthetic process(GO:1900620)
0.2 1.2 GO:0044351 macropinocytosis(GO:0044351)
0.2 1.2 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.2 0.5 GO:2000016 cellular response to nitrosative stress(GO:0071500) negative regulation of determination of dorsal identity(GO:2000016)
0.2 0.7 GO:1903294 regulation of glutamate secretion, neurotransmission(GO:1903294) positive regulation of glutamate secretion, neurotransmission(GO:1903296)
0.2 0.7 GO:0072054 renal outer medulla development(GO:0072054)
0.2 0.8 GO:0032348 negative regulation of aldosterone metabolic process(GO:0032345) negative regulation of aldosterone biosynthetic process(GO:0032348) negative regulation of cortisol biosynthetic process(GO:2000065)
0.2 0.5 GO:0046271 phenylpropanoid catabolic process(GO:0046271)
0.2 0.6 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.2 0.5 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.2 1.1 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.1 0.6 GO:0032789 saturated monocarboxylic acid metabolic process(GO:0032788) unsaturated monocarboxylic acid metabolic process(GO:0032789)
0.1 1.2 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.1 0.1 GO:0072236 metanephric loop of Henle development(GO:0072236)
0.1 0.9 GO:0038161 prolactin signaling pathway(GO:0038161)
0.1 0.4 GO:1990868 response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869)
0.1 0.4 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.1 0.4 GO:0007208 phospholipase C-activating serotonin receptor signaling pathway(GO:0007208)
0.1 1.7 GO:0045217 cell-cell junction maintenance(GO:0045217)
0.1 0.6 GO:0000103 sulfate assimilation(GO:0000103)
0.1 0.4 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.1 0.6 GO:0070295 renal water absorption(GO:0070295)
0.1 0.5 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.1 1.8 GO:0036158 outer dynein arm assembly(GO:0036158)
0.1 0.4 GO:0014054 positive regulation of gamma-aminobutyric acid secretion(GO:0014054)
0.1 0.4 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.1 0.3 GO:1900060 negative regulation of ceramide biosynthetic process(GO:1900060)
0.1 0.3 GO:1904274 tricellular tight junction assembly(GO:1904274)
0.1 0.3 GO:2000229 negative regulation of NAD(P)H oxidase activity(GO:0033861) pancreatic stellate cell proliferation(GO:0072343) regulation of pancreatic stellate cell proliferation(GO:2000229)
0.1 1.2 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.1 0.5 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.1 2.1 GO:0001573 ganglioside metabolic process(GO:0001573)
0.1 0.3 GO:1904980 regulation of endosome organization(GO:1904978) positive regulation of endosome organization(GO:1904980)
0.1 0.6 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.1 0.6 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.1 1.0 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.1 0.5 GO:0044375 regulation of peroxisome size(GO:0044375)
0.1 0.4 GO:0038163 thrombopoietin-mediated signaling pathway(GO:0038163)
0.1 0.4 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
0.1 0.7 GO:0097647 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.1 1.1 GO:0070842 aggresome assembly(GO:0070842)
0.1 0.2 GO:0034147 regulation of granuloma formation(GO:0002631) negative regulation of granuloma formation(GO:0002632) regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) tolerance induction to lipopolysaccharide(GO:0072573)
0.1 0.9 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.1 0.4 GO:0019086 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432) late viral transcription(GO:0019086)
0.1 0.8 GO:0070474 positive regulation of uterine smooth muscle contraction(GO:0070474)
0.1 0.7 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.1 1.0 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 0.3 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.1 1.5 GO:0018195 peptidyl-arginine modification(GO:0018195)
0.1 0.6 GO:0071763 nuclear membrane organization(GO:0071763)
0.1 0.3 GO:0036438 maintenance of lens transparency(GO:0036438)
0.1 0.5 GO:0016266 O-glycan processing(GO:0016266)
0.1 0.2 GO:0097401 synaptic vesicle lumen acidification(GO:0097401)
0.1 0.3 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.1 0.2 GO:0038033 positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway(GO:0038033)
0.1 0.7 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.1 0.5 GO:0060335 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.1 0.2 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.1 0.7 GO:0006642 triglyceride mobilization(GO:0006642)
0.1 0.3 GO:0038001 paracrine signaling(GO:0038001)
0.1 0.2 GO:1990859 cellular response to endothelin(GO:1990859)
0.1 0.3 GO:0097195 pilomotor reflex(GO:0097195)
0.1 0.4 GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.1 0.4 GO:0019348 dolichol metabolic process(GO:0019348)
0.1 0.3 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.1 0.7 GO:1904659 glucose transmembrane transport(GO:1904659)
0.1 3.0 GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189)
0.1 0.3 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.1 0.3 GO:1903367 positive regulation of fear response(GO:1903367) positive regulation of behavioral fear response(GO:2000987)
0.1 0.2 GO:0071879 response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016) positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.1 0.3 GO:0021888 hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888)
0.1 1.2 GO:0007263 nitric oxide mediated signal transduction(GO:0007263)
0.1 0.3 GO:0098528 skeletal muscle fiber differentiation(GO:0098528)
0.1 0.3 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.1 0.5 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168) negative regulation of oocyte maturation(GO:1900194)
0.0 0.3 GO:0006590 thyroid hormone generation(GO:0006590)
0.0 0.3 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.0 0.3 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.1 GO:0061739 protein lipidation involved in autophagosome assembly(GO:0061739)
0.0 0.3 GO:2000252 negative regulation of feeding behavior(GO:2000252)
0.0 0.4 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.2 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.0 0.2 GO:1990034 calcium ion export from cell(GO:1990034)
0.0 0.3 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0 0.1 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.0 0.2 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.0 0.1 GO:0033382 protein localization to secretory granule(GO:0033366) protein localization to mast cell secretory granule(GO:0033367) protease localization to mast cell secretory granule(GO:0033368) maintenance of protein location in mast cell secretory granule(GO:0033370) T cell secretory granule organization(GO:0033371) maintenance of protease location in mast cell secretory granule(GO:0033373) protein localization to T cell secretory granule(GO:0033374) protease localization to T cell secretory granule(GO:0033375) maintenance of protein location in T cell secretory granule(GO:0033377) maintenance of protease location in T cell secretory granule(GO:0033379) granzyme B localization to T cell secretory granule(GO:0033380) maintenance of granzyme B location in T cell secretory granule(GO:0033382)
0.0 1.7 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.3 GO:0031547 brain-derived neurotrophic factor receptor signaling pathway(GO:0031547)
0.0 0.5 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.0 GO:0045014 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.0 0.1 GO:0061734 parkin-mediated mitophagy in response to mitochondrial depolarization(GO:0061734)
0.0 0.1 GO:1903896 regulation of endoplasmic reticulum tubular network organization(GO:1903371) positive regulation of IRE1-mediated unfolded protein response(GO:1903896)
0.0 0.2 GO:0061641 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.1 GO:0033092 positive regulation of immature T cell proliferation in thymus(GO:0033092)
0.0 1.3 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.3 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.0 0.1 GO:0002223 stimulatory C-type lectin receptor signaling pathway(GO:0002223)
0.0 0.2 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 0.2 GO:0060330 regulation of response to interferon-gamma(GO:0060330)
0.0 0.4 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.3 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.7 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.3 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.0 0.1 GO:0015820 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.0 0.3 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0 0.3 GO:0036159 inner dynein arm assembly(GO:0036159)
0.0 0.1 GO:0080154 regulation of fertilization(GO:0080154)
0.0 0.2 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.0 0.2 GO:0006449 regulation of translational termination(GO:0006449)
0.0 0.7 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.0 0.3 GO:0007343 egg activation(GO:0007343)
0.0 0.1 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.3 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.0 0.2 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.2 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.0 0.1 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.0 0.3 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.4 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 0.1 GO:1903416 response to glycoside(GO:1903416)
0.0 0.4 GO:0097284 hepatocyte apoptotic process(GO:0097284)
0.0 0.1 GO:0010747 positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747)
0.0 0.2 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.0 0.5 GO:0097320 membrane tubulation(GO:0097320)
0.0 0.5 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.3 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.4 GO:0003417 growth plate cartilage development(GO:0003417)
0.0 0.3 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.5 GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.0 0.8 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.2 GO:1900378 positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.0 1.5 GO:0035383 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.0 1.8 GO:0060349 bone morphogenesis(GO:0060349)
0.0 0.2 GO:0071420 cellular response to histamine(GO:0071420)
0.0 0.3 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.0 0.4 GO:0022010 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.0 0.6 GO:0030857 negative regulation of epithelial cell differentiation(GO:0030857)
0.0 0.7 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.0 0.4 GO:0045109 intermediate filament organization(GO:0045109)
0.0 0.2 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.0 GO:0033087 negative regulation of immature T cell proliferation(GO:0033087)
0.0 0.1 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.0 0.6 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.3 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.3 GO:0045953 negative regulation of natural killer cell mediated cytotoxicity(GO:0045953)
0.0 0.4 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.1 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.0 GO:0052490 suppression by virus of host apoptotic process(GO:0019050) negative regulation by symbiont of host apoptotic process(GO:0033668) modulation by virus of host apoptotic process(GO:0039526) negative regulation by symbiont of host programmed cell death(GO:0052041) negative regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052490) positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902220)
0.0 0.3 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.0 0.4 GO:0042036 negative regulation of cytokine biosynthetic process(GO:0042036)
0.0 0.4 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.7 GO:0060395 SMAD protein signal transduction(GO:0060395)
0.0 0.6 GO:0045773 positive regulation of axon extension(GO:0045773)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.3 0.8 GO:0070939 Dsl1p complex(GO:0070939)
0.3 0.8 GO:0020016 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.2 0.5 GO:0036488 CHOP-C/EBP complex(GO:0036488)
0.2 0.8 GO:1990111 spermatoproteasome complex(GO:1990111)
0.2 3.6 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.2 1.2 GO:1990357 terminal web(GO:1990357)
0.1 2.7 GO:0043196 varicosity(GO:0043196)
0.1 1.5 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.1 1.5 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 0.9 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 0.3 GO:0032280 symmetric synapse(GO:0032280)
0.1 1.9 GO:0000421 autophagosome membrane(GO:0000421)
0.1 0.4 GO:0005594 collagen type IX trimer(GO:0005594)
0.1 0.3 GO:0035339 SPOTS complex(GO:0035339)
0.1 1.1 GO:0036157 outer dynein arm(GO:0036157)
0.1 1.2 GO:0045180 basal cortex(GO:0045180)
0.1 0.6 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.1 0.7 GO:0031983 vesicle lumen(GO:0031983)
0.1 0.3 GO:1990130 Iml1 complex(GO:1990130) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 0.3 GO:0044279 other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.1 2.6 GO:0008305 integrin complex(GO:0008305)
0.1 0.4 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.1 0.7 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.4 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.3 GO:0044308 axonal spine(GO:0044308)
0.0 1.5 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.0 0.3 GO:0008091 spectrin(GO:0008091)
0.0 0.3 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.6 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 1.0 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.2 GO:0032585 multivesicular body membrane(GO:0032585)
0.0 0.8 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.3 GO:0005796 Golgi lumen(GO:0005796)
0.0 1.3 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.2 GO:0097443 sorting endosome(GO:0097443)
0.0 1.1 GO:0045095 keratin filament(GO:0045095)
0.0 0.5 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.2 GO:0045293 mRNA editing complex(GO:0045293)
0.0 0.3 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.0 0.3 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 2.0 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.5 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.7 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.2 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.0 1.0 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.8 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.3 GO:0036156 inner dynein arm(GO:0036156)
0.0 0.4 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.4 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.5 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.1 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.3 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.7 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.3 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.1 GO:1990769 proximal neuron projection(GO:1990769)
0.0 0.6 GO:0030673 axolemma(GO:0030673)
0.0 0.4 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.1 GO:0042629 mast cell granule(GO:0042629)
0.0 1.1 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)
0.0 0.8 GO:0000786 nucleosome(GO:0000786)
0.0 0.3 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.5 GO:0005042 netrin receptor activity(GO:0005042)
0.4 2.5 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.3 2.7 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429)
0.3 3.6 GO:0051870 methotrexate binding(GO:0051870)
0.3 2.2 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.2 1.4 GO:0017040 ceramidase activity(GO:0017040)
0.2 0.9 GO:0004925 prolactin receptor activity(GO:0004925)
0.2 0.5 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.2 0.8 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.1 0.7 GO:0042610 CD8 receptor binding(GO:0042610)
0.1 0.6 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.1 0.4 GO:0005502 11-cis retinal binding(GO:0005502)
0.1 1.5 GO:0004579 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 1.2 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1 0.4 GO:1902379 chemoattractant activity involved in axon guidance(GO:1902379)
0.1 0.7 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.1 0.4 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.1 0.7 GO:0016892 endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.1 0.3 GO:0023030 MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
0.1 0.7 GO:0097322 7SK snRNA binding(GO:0097322)
0.1 0.3 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.1 0.6 GO:0005047 signal recognition particle binding(GO:0005047)
0.1 0.3 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1 0.6 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.1 0.3 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.1 0.7 GO:0035473 lipase binding(GO:0035473)
0.1 0.3 GO:0003883 CTP synthase activity(GO:0003883)
0.1 0.6 GO:0015288 porin activity(GO:0015288)
0.1 0.5 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.1 0.5 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.1 0.6 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.1 2.3 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.1 0.9 GO:0008430 selenium binding(GO:0008430)
0.1 1.1 GO:0043522 leucine zipper domain binding(GO:0043522)
0.1 0.7 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.1 0.8 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 1.0 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 0.6 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 1.1 GO:0045504 dynein heavy chain binding(GO:0045504)
0.1 0.3 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.1 0.9 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 0.2 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.1 0.3 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 2.3 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.3 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 0.2 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
0.0 0.6 GO:0010857 calcium-dependent protein kinase activity(GO:0010857)
0.0 0.2 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.0 0.3 GO:0031628 opioid receptor binding(GO:0031628)
0.0 0.5 GO:0031543 peptidyl-proline dioxygenase activity(GO:0031543)
0.0 0.5 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 1.5 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.2 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.0 0.1 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.0 0.2 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.0 1.3 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.6 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.3 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.2 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 4.2 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 1.0 GO:0031489 myosin V binding(GO:0031489)
0.0 0.4 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 1.3 GO:0004532 exoribonuclease activity(GO:0004532)
0.0 0.9 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.1 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.0 0.5 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.9 GO:0017127 cholesterol transporter activity(GO:0017127)
0.0 0.6 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.3 GO:1990405 protein antigen binding(GO:1990405)
0.0 0.2 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.4 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993) serotonin binding(GO:0051378)
0.0 0.5 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.3 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0 0.1 GO:0031849 olfactory receptor binding(GO:0031849)
0.0 0.2 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.6 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 1.0 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.6 GO:0005521 lamin binding(GO:0005521)
0.0 0.5 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.7 GO:0043274 phospholipase binding(GO:0043274)
0.0 0.5 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.3 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.0 0.3 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 1.0 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.1 GO:0019864 IgG binding(GO:0019864)
0.0 0.1 GO:0050649 testosterone 6-beta-hydroxylase activity(GO:0050649)
0.0 0.3 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 0.3 GO:0051400 BH domain binding(GO:0051400)
0.0 0.2 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.9 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.7 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 0.4 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.3 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.6 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.3 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.2 GO:0031432 titin binding(GO:0031432)
0.0 0.2 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.1 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.7 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.5 GO:0004812 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 0.4 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.1 GO:0001055 RNA polymerase II activity(GO:0001055)
0.0 0.3 GO:0045503 dynein light chain binding(GO:0045503)
0.0 0.2 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 1.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.6 GO:0035591 signaling adaptor activity(GO:0035591)
0.0 0.2 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.4 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.5 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.1 GO:0004064 arylesterase activity(GO:0004064)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.1 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 0.3 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 2.5 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 1.6 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.8 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.8 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.4 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 6.3 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.9 PID IGF1 PATHWAY IGF1 pathway
0.0 0.7 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 1.0 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.9 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 1.2 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.3 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.2 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.2 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.1 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.6 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.4 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 1.1 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.7 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.5 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.3 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.2 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.0 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 0.8 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1 0.2 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 1.8 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 0.5 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 0.7 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.1 2.0 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 0.6 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 0.5 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.5 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.9 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 2.5 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.7 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.4 REACTOME OPSINS Genes involved in Opsins
0.0 0.4 REACTOME PLATELET AGGREGATION PLUG FORMATION Genes involved in Platelet Aggregation (Plug Formation)
0.0 0.5 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 1.0 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.4 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 2.5 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.7 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.3 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.6 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 1.6 REACTOME TRANS GOLGI NETWORK VESICLE BUDDING Genes involved in trans-Golgi Network Vesicle Budding
0.0 0.2 REACTOME MRNA PROCESSING Genes involved in mRNA Processing
0.0 0.8 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.7 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.8 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.3 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.5 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.2 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.2 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.3 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.2 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.8 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.4 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.5 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.3 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.5 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.1 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.2 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 1.0 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.0 0.4 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.2 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.5 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.2 REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS Genes involved in NRIF signals cell death from the nucleus
0.0 0.2 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.2 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 0.2 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.6 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins