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12D miR HR13_24

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Results for Irx4

Z-value: 0.14

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Transcription factors associated with Irx4

Gene Symbol Gene ID Gene Info
ENSMUSG00000021604.9 Iroquois homeobox 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Irx4mm10_v2_chr13_+_73260473_73260497-0.294.0e-01Click!

Activity profile of Irx4 motif

Sorted Z-values of Irx4 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_24345305 0.11 ENSMUST00000114482.1
interleukin 1 receptor antagonist
chr2_+_24345282 0.09 ENSMUST00000114485.2
interleukin 1 receptor antagonist
chr1_+_45311538 0.07 ENSMUST00000087883.6
collagen, type III, alpha 1
chr11_-_11970540 0.05 ENSMUST00000109653.1
growth factor receptor bound protein 10
chr8_+_84872105 0.05 ENSMUST00000136026.1
ENSMUST00000170296.1
synaptonemal complex central element protein 2
chr6_-_83317589 0.05 ENSMUST00000005810.6
methylenetetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofolate cyclohydrolase
chr17_-_27133902 0.04 ENSMUST00000119227.1
ENSMUST00000025045.8
ubiquinol-cytochrome c reductase complex assembly factor 2
chr2_-_79908428 0.03 ENSMUST00000102652.3
ENSMUST00000102651.3
phosphodiesterase 1A, calmodulin-dependent
chr15_-_35938186 0.03 ENSMUST00000014457.8
cytochrome c oxidase subunit VIc
chr15_-_35938009 0.02 ENSMUST00000156915.1
cytochrome c oxidase subunit VIc
chr2_-_79908389 0.02 ENSMUST00000090756.4
phosphodiesterase 1A, calmodulin-dependent
chrX_-_161832112 0.02 ENSMUST00000129329.1
predicted gene 15205
chr3_-_57651667 0.02 ENSMUST00000160959.1
COMM domain containing 2
chr8_-_24725762 0.01 ENSMUST00000171438.1
ENSMUST00000171611.1
ENSMUST00000033958.7
a disintegrin and metallopeptidase domain 3 (cyritestin)
chr4_-_76344227 0.01 ENSMUST00000050757.9
protein tyrosine phosphatase, receptor type, D
chr6_-_3494587 0.01 ENSMUST00000049985.8
HEPACAM family member 2
chr9_-_58202281 0.00 ENSMUST00000163897.1
immunoglobulin superfamily containing leucine-rich repeat 2
chr18_-_37178493 0.00 ENSMUST00000181887.1
ENSMUST00000180516.1
predicted gene 10544

Network of associatons between targets according to the STRING database.

First level regulatory network of Irx4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.0 0.1 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0045352 interleukin-1, Type II receptor binding(GO:0005151) interleukin-1 receptor antagonist activity(GO:0005152) interleukin-1 Type I receptor antagonist activity(GO:0045352) interleukin-1 Type II receptor antagonist activity(GO:0045353)
0.0 0.0 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)