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12D miR HR13_24

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Results for Tcf7l1

Z-value: 0.61

Motif logo

Transcription factors associated with Tcf7l1

Gene Symbol Gene ID Gene Info
ENSMUSG00000055799.7 transcription factor 7 like 1 (T cell specific, HMG box)

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Tcf7l1mm10_v2_chr6_-_72788952_72789061-0.293.9e-01Click!

Activity profile of Tcf7l1 motif

Sorted Z-values of Tcf7l1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_87108656 0.90 ENSMUST00000051395.8
proline rich 11
chr2_+_157560078 0.89 ENSMUST00000153739.2
ENSMUST00000173595.1
ENSMUST00000109526.1
ENSMUST00000173839.1
ENSMUST00000173041.1
ENSMUST00000173793.1
ENSMUST00000172487.1
ENSMUST00000088484.5
neuronatin
chr1_+_136467958 0.89 ENSMUST00000047817.6
kinesin family member 14
chr4_+_11758147 0.83 ENSMUST00000029871.5
ENSMUST00000108303.1
cadherin 17
chr3_+_122895072 0.77 ENSMUST00000023820.5
fatty acid binding protein 2, intestinal
chr4_-_91376433 0.75 ENSMUST00000107109.2
ENSMUST00000107111.2
ENSMUST00000107120.1
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr6_-_148944750 0.70 ENSMUST00000111562.1
ENSMUST00000081956.5
family with sequence similarity 60, member A
chr1_+_158362261 0.68 ENSMUST00000046110.9
astrotactin 1
chr2_+_173022360 0.63 ENSMUST00000173997.1
RNA binding motif protein 38
chrX_+_6415736 0.61 ENSMUST00000143641.3
shroom family member 4
chr6_-_99726392 0.60 ENSMUST00000032152.8
ENSMUST00000101120.4
ENSMUST00000008273.6
prokineticin 2
chr19_-_41802028 0.59 ENSMUST00000026150.8
ENSMUST00000177495.1
ENSMUST00000163265.1
Rho GTPase activating protein 19
chr4_-_91376490 0.58 ENSMUST00000107124.3
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr11_-_54068932 0.57 ENSMUST00000093109.4
ENSMUST00000018755.3
PDZ and LIM domain 4
chr4_+_107367757 0.55 ENSMUST00000139560.1
NDC1 transmembrane nucleoporin
chr11_+_46055973 0.54 ENSMUST00000011400.7
a disintegrin and metallopeptidase domain 19 (meltrin beta)
chr2_+_173021902 0.54 ENSMUST00000029014.9
RNA binding motif protein 38
chr8_-_4259257 0.53 ENSMUST00000053252.7
cortexin 1
chr18_+_21072329 0.53 ENSMUST00000082235.4
meprin 1 beta
chr3_-_144932523 0.52 ENSMUST00000098549.3
expressed sequence AI747448
chr1_+_158362330 0.52 ENSMUST00000170718.1
astrotactin 1
chr1_-_183147461 0.50 ENSMUST00000171366.1
dispatched homolog 1 (Drosophila)
chr6_-_83527452 0.50 ENSMUST00000141904.1
actin, gamma 2, smooth muscle, enteric
chr11_+_3330781 0.46 ENSMUST00000136536.1
ENSMUST00000093399.4
phosphoinositide-3-kinase interacting protein 1
chr15_-_98953541 0.45 ENSMUST00000097014.5
tubulin, alpha 1A
chrX_-_48034842 0.43 ENSMUST00000039026.7
apelin
chr5_-_148392810 0.43 ENSMUST00000138257.1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr9_+_85842852 0.42 ENSMUST00000098500.3
trophoblast glycoprotein
chr19_-_46327121 0.42 ENSMUST00000041391.4
ENSMUST00000096029.5
pleckstrin and Sec7 domain containing
chr2_-_65529275 0.42 ENSMUST00000126837.1
sodium channel, voltage-gated, type III, alpha
chr8_+_70493156 0.42 ENSMUST00000008032.7
cytokine receptor-like factor 1
chr11_-_48946148 0.42 ENSMUST00000104958.1
protease (prosome, macropain) activator subunit 2B
chr12_-_54986363 0.41 ENSMUST00000173433.1
ENSMUST00000173803.1
bromodomain adjacent to zinc finger domain 1A
predicted gene 20403
chr9_+_98490522 0.41 ENSMUST00000035029.2
retinol binding protein 2, cellular
chrX_+_73483602 0.37 ENSMUST00000033741.8
ENSMUST00000169489.1
biglycan
chr12_+_119945957 0.36 ENSMUST00000058644.8
transmembrane protein 196
chr4_+_127172866 0.33 ENSMUST00000106094.2
discs, large (Drosophila) homolog-associated protein 3
chr4_+_141420757 0.33 ENSMUST00000102486.4
heat shock protein family, member 7 (cardiovascular)
chr12_-_98737405 0.33 ENSMUST00000170188.1
protein tyrosine phosphatase, non-receptor type 21
chr11_-_78497734 0.33 ENSMUST00000061174.6
sterile alpha and HEAT/Armadillo motif containing 1
chr7_-_142095266 0.33 ENSMUST00000039926.3
dual specificity phosphatase 8
chr10_-_117063764 0.32 ENSMUST00000047672.7
chaperonin containing Tcp1, subunit 2 (beta)
chr11_-_78497458 0.32 ENSMUST00000108287.3
sterile alpha and HEAT/Armadillo motif containing 1
chr17_+_12119274 0.31 ENSMUST00000024594.2
1-acylglycerol-3-phosphate O-acyltransferase 4 (lysophosphatidic acid acyltransferase, delta)
chr8_-_40511663 0.31 ENSMUST00000135269.1
ENSMUST00000034012.3
CCR4-NOT transcription complex, subunit 7
chr17_+_7925990 0.30 ENSMUST00000036370.7
T cell activation Rho GTPase activating protein
chr7_-_118129567 0.30 ENSMUST00000032888.7
ADP-ribosylation factor-like 6 interacting protein 1
chr5_-_123182704 0.30 ENSMUST00000154713.1
ENSMUST00000031398.7
4-hydroxyphenylpyruvic acid dioxygenase
chr4_-_141599835 0.30 ENSMUST00000141518.1
ENSMUST00000127455.1
ENSMUST00000105784.1
ENSMUST00000147785.1
filamin binding LIM protein 1
chr14_-_31019055 0.29 ENSMUST00000037739.6
guanine nucleotide binding protein-like 3 (nucleolar)
chr10_+_38965515 0.29 ENSMUST00000019992.5
laminin, alpha 4
chr19_-_5894100 0.29 ENSMUST00000055911.4
tigger transposable element derived 3
chr1_-_105659008 0.29 ENSMUST00000070699.8
phosphatidylinositol glycan anchor biosynthesis, class N
chr4_+_85205120 0.28 ENSMUST00000107188.3
SH3-domain GRB2-like 2
chr19_-_46338632 0.28 ENSMUST00000051234.8
ENSMUST00000167861.1
CUE domain containing 2
chr13_-_55488038 0.28 ENSMUST00000109921.2
ENSMUST00000109923.2
ENSMUST00000021950.8
drebrin 1
chr4_+_129513581 0.28 ENSMUST00000062356.6
MARCKS-like 1
chrX_+_151198078 0.28 ENSMUST00000184730.1
ENSMUST00000184392.1
ENSMUST00000096285.4
WNK lysine deficient protein kinase 3
chr5_+_33983534 0.28 ENSMUST00000114382.1
predicted gene 1673
chr9_+_110132015 0.28 ENSMUST00000088716.5
ENSMUST00000111969.1
ENSMUST00000035057.7
ENSMUST00000111966.1
ENSMUST00000111968.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
chr9_+_119402444 0.28 ENSMUST00000035093.8
ENSMUST00000165044.1
activin receptor IIB
chr14_+_50924968 0.27 ENSMUST00000049411.5
ENSMUST00000136753.1
ENSMUST00000154288.1
apurinic/apyrimidinic endonuclease 1
chr17_-_70851189 0.26 ENSMUST00000059775.8
TGFB-induced factor homeobox 1
chr6_-_47594967 0.26 ENSMUST00000081721.6
ENSMUST00000114618.1
ENSMUST00000114616.1
enhancer of zeste homolog 2 (Drosophila)
chr8_-_40511298 0.26 ENSMUST00000149992.1
CCR4-NOT transcription complex, subunit 7
chr14_+_101729907 0.25 ENSMUST00000100337.3
LIM domain only 7
chr5_+_65131184 0.25 ENSMUST00000031089.5
ENSMUST00000101191.3
kelch-like 5
chr12_+_31265279 0.25 ENSMUST00000002979.8
ENSMUST00000170495.1
laminin B1
chr14_-_70524068 0.25 ENSMUST00000022692.3
surfactant associated protein C
chr4_+_85205417 0.25 ENSMUST00000030212.8
ENSMUST00000107189.1
ENSMUST00000107184.1
SH3-domain GRB2-like 2
chr4_+_48585135 0.24 ENSMUST00000030032.6
transmembrane protein with EGF-like and two follistatin-like domains 1
chr4_-_34882919 0.24 ENSMUST00000098163.2
ENSMUST00000047950.5
zinc finger protein 292
chr7_+_45216671 0.24 ENSMUST00000134420.1
TEA domain family member 2
chr1_+_88227005 0.24 ENSMUST00000061013.6
ENSMUST00000113130.1
maestro heat-like repeat family member 2A
chr18_+_4921662 0.24 ENSMUST00000143254.1
supervillin
chr2_+_163658370 0.23 ENSMUST00000164399.1
ENSMUST00000064703.6
ENSMUST00000099105.2
ENSMUST00000152418.1
ENSMUST00000126182.1
ENSMUST00000131228.1
protein kinase inhibitor, gamma
chr11_+_46404720 0.23 ENSMUST00000063166.5
family with sequence similarity 71, member B
chr4_+_107802277 0.23 ENSMUST00000106733.2
ENSMUST00000030356.3
ENSMUST00000106732.2
ENSMUST00000126573.1
low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
chr3_-_50443603 0.22 ENSMUST00000029297.4
solute carrier family 7 (cationic amino acid transporter, y+ system), member 11
chr12_+_31265234 0.22 ENSMUST00000169088.1
laminin B1
chr12_-_84408991 0.22 ENSMUST00000120942.1
ENSMUST00000110272.2
ectonucleoside triphosphate diphosphohydrolase 5
chr14_-_98169542 0.22 ENSMUST00000069334.7
ENSMUST00000071533.6
dachshund 1 (Drosophila)
chr5_+_33983437 0.21 ENSMUST00000114384.1
ENSMUST00000094869.5
ENSMUST00000114383.1
predicted gene 1673
chr11_-_87074055 0.21 ENSMUST00000020804.7
glycerophosphodiester phosphodiesterase domain containing 1
chr13_+_94083490 0.21 ENSMUST00000156071.1
lipoma HMGIC fusion partner-like 2
chr2_+_124610573 0.21 ENSMUST00000103239.3
ENSMUST00000103240.2
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
chr1_-_12991109 0.20 ENSMUST00000115403.2
ENSMUST00000115402.1
solute carrier organic anion transporter family, member 5A1
chr7_+_87246649 0.20 ENSMUST00000068829.5
ENSMUST00000032781.7
NADPH oxidase 4
chr7_+_100493795 0.20 ENSMUST00000129324.1
uncoupling protein 2 (mitochondrial, proton carrier)
chr2_+_121357714 0.20 ENSMUST00000125812.1
ENSMUST00000078222.2
ENSMUST00000125221.1
ENSMUST00000150271.1
creatine kinase, mitochondrial 1, ubiquitous
chr3_-_57575760 0.20 ENSMUST00000029380.7
WW domain containing transcription regulator 1
chr10_-_22731336 0.20 ENSMUST00000127698.1
TATA box binding protein-like 1
chr9_-_65021645 0.19 ENSMUST00000036615.5
protein tyrosine phosphatase-like A domain containing 1
chr3_-_144205165 0.19 ENSMUST00000120539.1
LIM domain only 4
chr9_+_90163057 0.19 ENSMUST00000113059.1
ENSMUST00000167122.1
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 7
chr2_-_20968526 0.19 ENSMUST00000141298.2
ENSMUST00000125783.2
Rho GTPase activating protein 21
chr7_-_83884289 0.19 ENSMUST00000094216.3
mesoderm development candidate 1
chr12_+_84996309 0.18 ENSMUST00000168977.1
ENSMUST00000021670.8
YLP motif containing 1
chr8_-_84773381 0.18 ENSMUST00000109764.1
nuclear factor I/X
chr9_+_35423582 0.18 ENSMUST00000154652.1
cell adhesion molecule-related/down-regulated by oncogenes
chr12_+_84996487 0.17 ENSMUST00000101202.3
YLP motif containing 1
chr1_+_181150926 0.17 ENSMUST00000134115.1
ENSMUST00000111059.1
cornichon homolog 4 (Drosophila)
chr12_+_24498570 0.17 ENSMUST00000075954.7
TATA box binding protein (Tbp)-associated factor, RNA polymerase I, B
chr11_+_69846665 0.16 ENSMUST00000019605.2
phospholipid scramblase 3
chr12_+_84409039 0.16 ENSMUST00000081828.6
coiled-coil domain containing 176
chr17_-_46202576 0.16 ENSMUST00000024749.7
polymerase (DNA directed), eta (RAD 30 related)
chr14_+_101840501 0.16 ENSMUST00000159026.1
LIM domain only 7
chr5_-_138155694 0.16 ENSMUST00000132318.1
ENSMUST00000049393.8
zinc finger protein 113
chr11_+_69846374 0.15 ENSMUST00000108632.1
phospholipid scramblase 3
chr2_+_35582829 0.15 ENSMUST00000135741.1
disabled 2 interacting protein
chr2_+_138278481 0.15 ENSMUST00000075410.4
BTB (POZ) domain containing 3
chr7_-_43489967 0.15 ENSMUST00000107974.1
IgLON family member 5
chr10_+_80151154 0.14 ENSMUST00000146516.1
ENSMUST00000144526.1
midnolin
chr19_-_5729618 0.14 ENSMUST00000116558.2
ENSMUST00000099955.3
ENSMUST00000161368.1
family with sequence similarity 89, member B
chr8_+_79028587 0.14 ENSMUST00000119254.1
zinc finger protein 827
chr11_+_96316684 0.14 ENSMUST00000049241.7
homeobox B4
chr7_-_27195727 0.14 ENSMUST00000163311.2
ENSMUST00000126211.1
small nuclear ribonucleoprotein polypeptide A
chr7_+_27591513 0.14 ENSMUST00000108344.2
thymoma viral proto-oncogene 2
chr12_-_41485751 0.13 ENSMUST00000043884.4
leucine rich repeat protein 3, neuronal
chr13_-_97747399 0.13 ENSMUST00000144993.1
RIKEN cDNA 5330416C01 gene
chr10_-_25536114 0.13 ENSMUST00000179685.1
small leucine-rich protein 1
chrX_+_169879596 0.13 ENSMUST00000112105.1
ENSMUST00000078947.5
midline 1
chr4_+_57782153 0.13 ENSMUST00000124581.1
A kinase (PRKA) anchor protein 2
chr7_+_82867327 0.13 ENSMUST00000082237.5
mex3 homolog B (C. elegans)
chr1_+_59482133 0.13 ENSMUST00000114246.2
ENSMUST00000037105.6
frizzled homolog 7 (Drosophila)
chr7_+_126760591 0.13 ENSMUST00000091328.2
mitogen-activated protein kinase 3
chr5_-_31241215 0.13 ENSMUST00000068997.3
predicted gene 9970
chr4_+_99656299 0.13 ENSMUST00000087285.3
forkhead box D3
chr2_-_65567505 0.13 ENSMUST00000100069.2
sodium channel, voltage-gated, type III, alpha
chr1_+_165788681 0.13 ENSMUST00000161971.1
ENSMUST00000178336.1
ENSMUST00000005907.5
ENSMUST00000027849.4
CD247 antigen
chr4_+_127021311 0.13 ENSMUST00000030623.7
splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated)
chr7_-_105787544 0.12 ENSMUST00000078482.5
ENSMUST00000154659.1
dachsous 1 (Drosophila)
chr14_-_52020698 0.12 ENSMUST00000067549.7
zinc finger protein 219
chr5_+_148265265 0.12 ENSMUST00000071878.5
microtubule associated tumor suppressor candidate 2
chr7_+_98835104 0.12 ENSMUST00000165122.1
ENSMUST00000067495.2
wingless-related MMTV integration site 11
chr8_+_79028317 0.11 ENSMUST00000087927.4
ENSMUST00000098614.2
zinc finger protein 827
chr7_+_73375494 0.11 ENSMUST00000094312.5
ENSMUST00000119206.1
RGM domain family, member A
chr7_-_105787567 0.11 ENSMUST00000144189.1
dachsous 1 (Drosophila)
chr6_-_122340525 0.11 ENSMUST00000112600.2
polyhomeotic-like 1 (Drosophila)
chr19_-_37330613 0.11 ENSMUST00000131070.1
insulin degrading enzyme
chr14_+_101840602 0.11 ENSMUST00000159314.1
LIM domain only 7
chr18_-_12819842 0.11 ENSMUST00000119043.1
oxysterol binding protein-like 1A
chr4_+_108479081 0.11 ENSMUST00000155068.1
zinc finger, CCHC domain containing 11
chr3_-_95106779 0.10 ENSMUST00000005768.7
ENSMUST00000107232.2
ENSMUST00000107236.2
phosphatidylinositol-4-phosphate 5-kinase, type 1 alpha
chr4_+_115057683 0.10 ENSMUST00000161601.1
T cell acute lymphocytic leukemia 1
chr1_+_161142706 0.10 ENSMUST00000111608.1
ENSMUST00000052245.8
ankyrin repeat domain 45
chr1_+_107361929 0.10 ENSMUST00000027566.2
serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 11
chrX_+_71556874 0.10 ENSMUST00000123100.1
high mobility group box 3
chr2_-_65567465 0.10 ENSMUST00000066432.5
sodium channel, voltage-gated, type III, alpha
chr16_-_34513944 0.10 ENSMUST00000151491.1
ENSMUST00000114960.2
kalirin, RhoGEF kinase
chr1_+_131153175 0.09 ENSMUST00000112446.2
ENSMUST00000068805.7
ENSMUST00000068791.4
eukaryotic translation initiation factor 2D
chr9_+_69989466 0.09 ENSMUST00000034754.5
ENSMUST00000085393.6
ENSMUST00000117450.1
BCL2/adenovirus E1B interacting protein 2
chr9_+_90162978 0.09 ENSMUST00000113060.1
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 7
chr5_+_148265307 0.09 ENSMUST00000110514.1
microtubule associated tumor suppressor candidate 2
chr15_-_79328201 0.09 ENSMUST00000173163.1
ENSMUST00000047816.8
ENSMUST00000172403.2
ENSMUST00000173632.1
phospholipase A2, group VI
chr9_+_21616166 0.09 ENSMUST00000034707.8
ENSMUST00000098948.3
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
chr6_+_51432663 0.09 ENSMUST00000005103.5
nuclear factor, erythroid derived 2, like 3
chr4_-_94650092 0.09 ENSMUST00000107101.1
leucine rich repeat containing 19
chr10_+_79988584 0.09 ENSMUST00000004784.4
ENSMUST00000105374.1
calponin 2
chr17_+_28530834 0.09 ENSMUST00000025060.2
armadillo repeat containing 12
chr8_-_85067982 0.09 ENSMUST00000177563.1
predicted gene 5741
chr7_-_49636847 0.09 ENSMUST00000032717.6
developing brain homeobox 1
chrX_-_57392962 0.09 ENSMUST00000114730.1
RNA binding motif protein, X chromosome
chr6_+_38918969 0.08 ENSMUST00000003017.6
thromboxane A synthase 1, platelet
chr5_+_148265202 0.08 ENSMUST00000110515.2
microtubule associated tumor suppressor candidate 2
chr6_-_3498297 0.08 ENSMUST00000183736.1
HEPACAM family member 2
chr1_+_165788746 0.08 ENSMUST00000161559.2
CD247 antigen
chr11_+_108920800 0.08 ENSMUST00000140821.1
axin2
chr10_-_116473418 0.08 ENSMUST00000087965.4
ENSMUST00000164271.1
potassium large conductance calcium-activated channel, subfamily M, beta member 4
chr4_-_94650134 0.08 ENSMUST00000053419.2
leucine rich repeat containing 19
chr8_-_69184177 0.08 ENSMUST00000185176.1
leucine zipper, putative tumor suppressor 1
chr3_+_19957037 0.08 ENSMUST00000091309.5
ENSMUST00000108329.1
ENSMUST00000003714.6
ceruloplasmin
chr17_-_6961156 0.07 ENSMUST00000063683.6
T cell activation GTPase activating protein 1
chr4_-_126468580 0.07 ENSMUST00000097888.3
argonaute RISC catalytic subunit 1
chr14_-_70176787 0.07 ENSMUST00000153735.1
PDZ and LIM domain 2
chr6_+_54039558 0.07 ENSMUST00000046856.7
chimerin (chimaerin) 2
chr14_+_65605267 0.07 ENSMUST00000079469.6
nuclear GTPase, germinal center associated
chr17_+_34031787 0.07 ENSMUST00000044858.8
retinoid X receptor beta
chr9_-_110117303 0.07 ENSMUST00000136969.1
DEAH (Asp-Glu-Ala-His) box polypeptide 30
chr10_+_80300997 0.07 ENSMUST00000140828.1
ENSMUST00000138909.1
adenomatosis polyposis coli 2
chr5_-_147307264 0.07 ENSMUST00000031650.3
caudal type homeobox 2
chr6_-_52218686 0.07 ENSMUST00000134367.2
homeobox A7
chr15_-_79328154 0.07 ENSMUST00000166977.2
phospholipase A2, group VI
chr7_+_35186370 0.07 ENSMUST00000135452.1
ENSMUST00000001854.5
solute carrier family 7 (cationic amino acid transporter, y+ system), member 10
chr3_-_57575907 0.06 ENSMUST00000120977.1
WW domain containing transcription regulator 1
chr18_-_46212595 0.06 ENSMUST00000037011.4
tripartite motif-containing 36
chr7_+_127233227 0.06 ENSMUST00000056232.6
zinc finger protein 553
chr9_-_45984816 0.06 ENSMUST00000172450.1
platelet-activating factor acetylhydrolase, isoform 1b, subunit 2
chr6_+_83137089 0.06 ENSMUST00000121093.1
ENSMUST00000087938.4
rhotekin
chr4_+_125029992 0.06 ENSMUST00000030684.7
guanine nucleotide binding protein-like 2 (nucleolar)
chr11_+_3649759 0.06 ENSMUST00000140242.1
microrchidia 2A
chr2_+_27079371 0.06 ENSMUST00000091233.6
ADAMTS-like 2
chr17_-_34603675 0.06 ENSMUST00000015622.7
ring finger protein 5
chr7_+_127233044 0.06 ENSMUST00000106312.3
zinc finger protein 553
chr1_+_132008285 0.06 ENSMUST00000146432.1
ELK4, member of ETS oncogene family
chr11_-_101302206 0.06 ENSMUST00000140706.1
ENSMUST00000170502.1
ENSMUST00000172233.1
ENSMUST00000130916.1
beclin 1, autophagy related
chr15_-_58214882 0.06 ENSMUST00000022986.6
F-box protein 32
chr2_-_165034821 0.06 ENSMUST00000153905.1
ENSMUST00000040381.8
nuclear receptor coactivator 5
chr10_+_60106452 0.06 ENSMUST00000165024.2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan 2
chr13_+_109903089 0.06 ENSMUST00000120664.1
phosphodiesterase 4D, cAMP specific

Network of associatons between targets according to the STRING database.

First level regulatory network of Tcf7l1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0033624 negative regulation of integrin activation(GO:0033624)
0.3 0.8 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.2 0.6 GO:0060983 epicardium-derived cardiac vascular smooth muscle cell differentiation(GO:0060983)
0.1 0.4 GO:1904020 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397) positive regulation of corticotropin-releasing hormone secretion(GO:0051466) regulation of G-protein coupled receptor internalization(GO:1904020)
0.1 0.6 GO:0046684 response to pyrethroid(GO:0046684)
0.1 0.5 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.1 0.3 GO:0010643 cell communication by chemical coupling(GO:0010643)
0.1 0.3 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.1 1.2 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.1 1.2 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.1 0.6 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.1 0.3 GO:0071707 immunoglobulin heavy chain V-D-J recombination(GO:0071707)
0.1 0.4 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.1 0.3 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.1 0.3 GO:0006572 tyrosine catabolic process(GO:0006572)
0.1 0.2 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.1 0.6 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290) negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.1 0.3 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.1 0.2 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.1 0.4 GO:0006776 vitamin A metabolic process(GO:0006776)
0.1 0.3 GO:0071787 regulation of L-glutamate transport(GO:0002036) endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 0.2 GO:0006235 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212) dTTP metabolic process(GO:0046075)
0.0 0.1 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.0 0.2 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
0.0 0.5 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.0 0.3 GO:0072307 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.0 0.3 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.0 0.2 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.0 0.1 GO:0001712 ectodermal cell fate commitment(GO:0001712)
0.0 0.4 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.2 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.1 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.0 0.1 GO:0042940 D-amino acid transport(GO:0042940)
0.0 0.3 GO:1904816 positive regulation of protein localization to chromosome, telomeric region(GO:1904816)
0.0 0.1 GO:0007403 glial cell fate determination(GO:0007403)
0.0 0.1 GO:0060775 mediolateral intercalation(GO:0060031) planar cell polarity pathway involved in gastrula mediolateral intercalation(GO:0060775)
0.0 0.2 GO:0071494 cellular response to UV-C(GO:0071494)
0.0 0.2 GO:0097473 cellular response to light intensity(GO:0071484) cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.0 0.4 GO:0015809 arginine transport(GO:0015809)
0.0 0.2 GO:2000304 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of arachidonic acid secretion(GO:0090238) positive regulation of ceramide biosynthetic process(GO:2000304)
0.0 0.0 GO:1900368 regulation of RNA interference(GO:1900368)
0.0 0.5 GO:0060539 diaphragm development(GO:0060539)
0.0 0.2 GO:1902475 L-glutamate transmembrane transport(GO:0089711) L-alpha-amino acid transmembrane transport(GO:1902475)
0.0 0.3 GO:0043247 telomere maintenance in response to DNA damage(GO:0043247)
0.0 0.2 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.0 0.3 GO:0048617 embryonic foregut morphogenesis(GO:0048617)
0.0 0.1 GO:0072697 protein localization to cell cortex(GO:0072697)
0.0 0.1 GO:0000189 MAPK import into nucleus(GO:0000189)
0.0 0.3 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.1 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.0 0.8 GO:0050892 intestinal absorption(GO:0050892)
0.0 0.3 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.1 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.0 0.1 GO:0048539 bone marrow development(GO:0048539)
0.0 0.2 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.0 0.3 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.4 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.8 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 0.1 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0 0.2 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 0.1 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.1 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.1 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.2 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.2 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.0 GO:2000646 positive regulation of receptor catabolic process(GO:2000646)
0.0 0.3 GO:0048339 paraxial mesoderm development(GO:0048339)
0.0 0.1 GO:0010992 bradykinin catabolic process(GO:0010815) ubiquitin homeostasis(GO:0010992)
0.0 0.5 GO:1901998 toxin transport(GO:1901998)
0.0 0.1 GO:0014894 response to inactivity(GO:0014854) response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.1 GO:0061366 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0 0.3 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.0 0.1 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.0 GO:0021526 medial motor column neuron differentiation(GO:0021526)
0.0 0.2 GO:0050667 homocysteine metabolic process(GO:0050667)
0.0 0.1 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.0 0.1 GO:0035280 miRNA loading onto RISC involved in gene silencing by miRNA(GO:0035280)
0.0 0.1 GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.3 GO:1902737 dendritic filopodium(GO:1902737)
0.2 0.5 GO:0005607 laminin-2 complex(GO:0005607)
0.1 0.4 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.1 0.4 GO:0008623 CHRAC(GO:0008623)
0.1 0.6 GO:0042025 host cell nucleus(GO:0042025) host cell nuclear part(GO:0044094)
0.1 0.2 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.1 0.3 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.1 0.8 GO:0045179 apical cortex(GO:0045179)
0.0 0.6 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0 0.2 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.2 GO:1990032 parallel fiber(GO:1990032)
0.0 0.6 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.7 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.2 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.0 0.1 GO:0033193 Lsd1/2 complex(GO:0033193)
0.0 0.9 GO:0051233 spindle midzone(GO:0051233)
0.0 0.2 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.3 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.1 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.2 GO:0097208 alveolar lamellar body(GO:0097208)
0.0 0.1 GO:0034271 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 0.1 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.2 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.3 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.0 GO:0042272 nucleocytoplasmic shuttling complex(GO:0031074) nuclear RNA export factor complex(GO:0042272)
0.0 0.1 GO:0042382 paraspeckles(GO:0042382)
0.0 0.6 GO:0016460 myosin II complex(GO:0016460)
0.0 0.2 GO:0071564 npBAF complex(GO:0071564)
0.0 0.9 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.3 GO:0005605 basal lamina(GO:0005605)
0.0 0.3 GO:0045120 pronucleus(GO:0045120)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.1 0.8 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.1 0.5 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.1 0.3 GO:0008311 double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.1 0.3 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.1 0.5 GO:0043208 glycosphingolipid binding(GO:0043208)
0.1 0.2 GO:0038025 reelin receptor activity(GO:0038025)
0.1 0.4 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.1 0.4 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.0 0.2 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.0 0.2 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.5 GO:0015197 peptide transporter activity(GO:0015197)
0.0 0.2 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.0 0.3 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0 0.2 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.2 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.0 0.3 GO:0034711 inhibin binding(GO:0034711)
0.0 0.6 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.7 GO:0031005 filamin binding(GO:0031005)
0.0 0.3 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.4 GO:0019841 retinol binding(GO:0019841)
0.0 0.2 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.6 GO:0031402 sodium ion binding(GO:0031402)
0.0 0.9 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.3 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.1 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.0 0.1 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.0 0.5 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.1 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.0 0.4 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.0 1.1 GO:0042805 actinin binding(GO:0042805)
0.0 0.2 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 0.2 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 0.4 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.2 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.0 GO:0033680 ATP-dependent DNA/RNA helicase activity(GO:0033680)
0.0 1.5 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.4 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.1 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.2 GO:0005522 profilin binding(GO:0005522)
0.0 1.2 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.2 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 0.2 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.3 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.2 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.2 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.3 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.4 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.2 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.5 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.4 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.3 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.5 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.2 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.6 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.5 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.7 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.3 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.5 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.1 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.5 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.3 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.2 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.3 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D