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12D miR HR13_24

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Results for Creb3l2

Z-value: 1.68

Motif logo

Transcription factors associated with Creb3l2

Gene Symbol Gene ID Gene Info
ENSMUSG00000038648.5 cAMP responsive element binding protein 3-like 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Creb3l2mm10_v2_chr6_-_37442095_374421540.471.4e-01Click!

Activity profile of Creb3l2 motif

Sorted Z-values of Creb3l2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr13_-_92131494 4.98 ENSMUST00000099326.3
ENSMUST00000146492.1
RAS protein-specific guanine nucleotide-releasing factor 2
chr2_+_180725263 4.97 ENSMUST00000094218.3
solute carrier family 17, member 9
chr4_+_104766308 3.86 ENSMUST00000031663.3
complement component 8, beta polypeptide
chr4_+_104766334 3.77 ENSMUST00000065072.6
complement component 8, beta polypeptide
chr18_+_65800543 3.06 ENSMUST00000025394.6
ENSMUST00000153193.1
SEC11 homolog C (S. cerevisiae)
chr5_-_139814231 2.58 ENSMUST00000044002.4
transmembrane protein 184a
chr2_+_160880642 2.40 ENSMUST00000109456.2
lipin 3
chr4_-_106617232 2.23 ENSMUST00000106788.1
cDNA sequence BC055111
chr4_+_133553370 2.06 ENSMUST00000042706.2
nuclear receptor subfamily 0, group B, member 2
chr14_-_70443442 2.05 ENSMUST00000000793.5
polymerase (RNA) III (DNA directed) polypeptide D
chr2_+_129198757 1.90 ENSMUST00000028880.3
solute carrier family 20, member 1
chr14_-_70443219 1.86 ENSMUST00000180358.1
polymerase (RNA) III (DNA directed) polypeptide D
chr17_-_26199008 1.86 ENSMUST00000142410.1
ENSMUST00000120333.1
ENSMUST00000039113.7
protein disulfide isomerase associated 2
chr9_+_21955747 1.85 ENSMUST00000053583.5
SWIM type zinc finger 7 associated protein 1
chr8_-_106136890 1.84 ENSMUST00000115979.2
epithelial splicing regulatory protein 2
chr19_-_6840590 1.84 ENSMUST00000170516.2
ENSMUST00000025903.5
ribosomal protein S6 kinase, polypeptide 4
chr5_-_139814025 1.83 ENSMUST00000146780.1
transmembrane protein 184a
chr8_+_14911663 1.81 ENSMUST00000084207.5
ENSMUST00000161162.1
ENSMUST00000110800.2
Rho guanine nucleotide exchange factor (GEF) 10
chr3_+_106482427 1.81 ENSMUST00000029508.4
DENN/MADD domain containing 2D
chr7_+_30169861 1.78 ENSMUST00000085668.4
predicted gene 5113
chr15_-_83350151 1.76 ENSMUST00000067215.7
ADP-ribosylation factor GTPase activating protein 3
chr10_-_20725023 1.74 ENSMUST00000020165.7
phosphodiesterase 7B
chrX_+_50841434 1.70 ENSMUST00000114887.2
RIKEN cDNA 2610018G03 gene
chr7_+_78913765 1.67 ENSMUST00000038142.8
interferon-stimulated protein
chr13_-_119408985 1.64 ENSMUST00000099149.3
ENSMUST00000069902.6
ENSMUST00000109204.1
nicotinamide nucleotide transhydrogenase
chr3_+_123267445 1.46 ENSMUST00000047923.7
Sec24 related gene family, member D (S. cerevisiae)
chr6_-_13871459 1.39 ENSMUST00000155856.1
RIKEN cDNA 2610001J05 gene
chr4_-_106800249 1.38 ENSMUST00000148688.1
acyl-CoA thioesterase 11
chr17_-_56276750 1.36 ENSMUST00000058136.8
toll-like receptor adaptor molecule 1
chr6_-_13871477 1.36 ENSMUST00000139231.1
RIKEN cDNA 2610001J05 gene
chr9_-_43239816 1.31 ENSMUST00000034512.5
OAF homolog (Drosophila)
chr11_+_54438188 1.31 ENSMUST00000046835.7
folliculin interacting protein 1
chr5_+_129941949 1.29 ENSMUST00000051758.7
ENSMUST00000073945.4
vitamin K epoxide reductase complex, subunit 1-like 1
chr18_-_40219324 1.26 ENSMUST00000025364.4
Yip1 domain family, member 5
chrX_+_139563316 1.23 ENSMUST00000113027.1
ring finger protein 128
chr7_+_19094594 1.18 ENSMUST00000049454.5
sine oculis-related homeobox 5
chr15_-_34495180 1.18 ENSMUST00000022946.5
heat-responsive protein 12
chr11_-_120572822 1.15 ENSMUST00000168360.1
prolyl 4-hydroxylase, beta polypeptide
chr7_+_78914216 1.14 ENSMUST00000120331.2
interferon-stimulated protein
chr8_-_105255100 1.08 ENSMUST00000093217.2
ENSMUST00000161745.2
ENSMUST00000136822.2
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9
chr15_-_102136225 1.07 ENSMUST00000154032.1
SPRY domain containing 3
chr6_+_87042838 1.07 ENSMUST00000113658.1
ENSMUST00000113657.1
ENSMUST00000113655.1
ENSMUST00000032057.7
glutamine fructose-6-phosphate transaminase 1
chr4_-_119422355 1.07 ENSMUST00000106316.1
ENSMUST00000030385.6
phosphopantothenoylcysteine synthetase
chr12_+_17544873 1.06 ENSMUST00000171737.1
ornithine decarboxylase, structural 1
chr2_-_180334665 1.04 ENSMUST00000015771.2
GATA binding protein 5
chr7_+_27195781 1.04 ENSMUST00000108379.1
ENSMUST00000179391.1
cDNA sequence BC024978
chr9_-_87255536 1.01 ENSMUST00000093802.4
RIKEN cDNA 4922501C03 gene
chr3_-_108086590 0.99 ENSMUST00000102638.1
ENSMUST00000102637.1
adenosine monophosphate deaminase 2
chr15_+_99591028 0.98 ENSMUST00000169082.1
aquaporin 5
chr3_-_27710413 0.96 ENSMUST00000046157.4
fibronectin type III domain containing 3B
chr4_+_155993305 0.95 ENSMUST00000105578.1
stromal cell derived factor 4
chr7_-_30169701 0.95 ENSMUST00000062181.7
zinc finger protein 146
chr9_+_89909775 0.91 ENSMUST00000034912.4
ENSMUST00000034909.4
RAS protein-specific guanine nucleotide-releasing factor 1
chr6_-_83317589 0.89 ENSMUST00000005810.6
methylenetetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofolate cyclohydrolase
chr11_-_103954015 0.89 ENSMUST00000103075.4
N-ethylmaleimide sensitive fusion protein
chr18_+_75018709 0.88 ENSMUST00000039608.7
dymeclin
chr3_+_40540751 0.88 ENSMUST00000091186.3
inturned planar cell polarity effector homolog (Drosophila)
chr8_-_124663368 0.87 ENSMUST00000034464.6
RIKEN cDNA 2310022B05 gene
chr9_-_25151772 0.86 ENSMUST00000008573.7
HERPUD family member 2
chr10_+_61680302 0.85 ENSMUST00000020285.8
SAR1 gene homolog A (S. cerevisiae)
chr5_+_143403819 0.84 ENSMUST00000110731.2
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
chr2_+_144368961 0.84 ENSMUST00000028911.8
ENSMUST00000147747.1
ENSMUST00000183618.1
cysteine and glycine-rich protein 2 binding protein
PET117 homolog (S. cerevisiae)
chr11_+_20201406 0.83 ENSMUST00000020358.5
ENSMUST00000109602.1
ENSMUST00000109601.1
RAB1, member RAS oncogene family
chr3_-_101604580 0.82 ENSMUST00000036493.6
ATPase, Na+/K+ transporting, alpha 1 polypeptide
chr11_-_120643643 0.78 ENSMUST00000141254.1
ENSMUST00000170556.1
ENSMUST00000151876.1
ENSMUST00000026133.8
ENSMUST00000139706.1
pyrroline-5-carboxylate reductase 1
chr11_-_100759740 0.77 ENSMUST00000107361.2
potassium voltage-gated channel, subfamily H (eag-related), member 4
chr19_+_46573362 0.77 ENSMUST00000026011.6
sideroflexin 2
chr15_-_97767798 0.77 ENSMUST00000129223.2
ENSMUST00000126854.2
ENSMUST00000135080.1
Rap guanine nucleotide exchange factor (GEF) 3
chr11_-_100759942 0.76 ENSMUST00000107363.2
potassium voltage-gated channel, subfamily H (eag-related), member 4
chr8_+_111033890 0.75 ENSMUST00000034441.7
alanyl-tRNA synthetase
chr5_-_45857473 0.75 ENSMUST00000016026.7
ENSMUST00000067997.6
ENSMUST00000045586.6
ligand dependent nuclear receptor corepressor-like
chr15_-_97767644 0.72 ENSMUST00000128775.2
ENSMUST00000134885.2
Rap guanine nucleotide exchange factor (GEF) 3
chr17_-_26939464 0.72 ENSMUST00000025027.8
ENSMUST00000114935.1
cutA divalent cation tolerance homolog (E. coli)
chr6_+_13871517 0.72 ENSMUST00000181090.1
ENSMUST00000181225.1
RIKEN cDNA 1110019D14 gene
chr15_-_3995708 0.70 ENSMUST00000046633.8
expressed sequence AW549877
chr15_+_34238026 0.70 ENSMUST00000022867.3
lysosomal-associated protein transmembrane 4B
chr10_-_52382074 0.70 ENSMUST00000020008.8
ENSMUST00000105475.2
golgi associated PDZ and coiled-coil motif containing
chr14_-_55643800 0.70 ENSMUST00000122358.1
transmembrane 9 superfamily member 1
chr3_-_63964659 0.69 ENSMUST00000161659.1
solute carrier family 33 (acetyl-CoA transporter), member 1
chr12_+_84451485 0.67 ENSMUST00000137170.1
lin-52 homolog (C. elegans)
chr2_-_130424242 0.66 ENSMUST00000089581.4
PC-esterase domain containing 1A
chr14_-_55643720 0.66 ENSMUST00000138085.1
transmembrane 9 superfamily member 1
chr11_-_97500340 0.64 ENSMUST00000056955.1
RIKEN cDNA 4933428G20 gene
chr2_-_92370999 0.63 ENSMUST00000176810.1
ENSMUST00000090582.4
glycosyltransferase-like 1B
chr5_+_137641334 0.63 ENSMUST00000177466.1
ENSMUST00000166099.2
sin3 associated polypeptide
chr2_+_150786735 0.63 ENSMUST00000045441.7
brain glycogen phosphorylase
chr18_+_75367529 0.59 ENSMUST00000026999.3
SMAD family member 7
chr13_+_90089705 0.59 ENSMUST00000012566.8
transmembrane protein 167
chr11_+_76672456 0.54 ENSMUST00000056184.1
basic helix-loop-helix family, member a9
chr11_+_44518959 0.54 ENSMUST00000019333.3
ring finger protein 145
chr2_+_132846638 0.54 ENSMUST00000028835.6
ENSMUST00000110122.3
cardiolipin synthase 1
chr6_+_56832059 0.54 ENSMUST00000031795.7
FK506 binding protein 9
chr6_+_87887814 0.54 ENSMUST00000113607.3
ENSMUST00000049966.5
coatomer protein complex, subunit gamma 1
chr2_-_92370968 0.53 ENSMUST00000176774.1
glycosyltransferase-like 1B
chr13_-_90089060 0.51 ENSMUST00000161396.1
X-ray repair complementing defective repair in Chinese hamster cells 4
chr2_-_92371039 0.51 ENSMUST00000068586.6
glycosyltransferase-like 1B
chr13_-_55321928 0.50 ENSMUST00000035242.7
RAB24, member RAS oncogene family
chr14_-_55643523 0.49 ENSMUST00000132338.1
transmembrane 9 superfamily member 1
chr10_+_128909866 0.49 ENSMUST00000026407.7
CD63 antigen
chr15_+_79516396 0.48 ENSMUST00000010974.7
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
chr10_+_80172934 0.48 ENSMUST00000041882.6
RIKEN cDNA 1600002K03 gene
chr12_-_84450944 0.47 ENSMUST00000085192.5
aldehyde dehydrogenase family 6, subfamily A1
chr4_+_148039097 0.47 ENSMUST00000141283.1
5,10-methylenetetrahydrofolate reductase
chr2_+_70661556 0.47 ENSMUST00000112201.1
ENSMUST00000028509.4
ENSMUST00000133432.1
ENSMUST00000112205.1
golgi reassembly stacking protein 2
chr11_+_95712673 0.46 ENSMUST00000107717.1
zinc finger protein 652
chr14_-_55643251 0.46 ENSMUST00000120041.1
ENSMUST00000121937.1
ENSMUST00000133707.1
ENSMUST00000002391.8
ENSMUST00000121791.1
transmembrane 9 superfamily member 1
chr3_-_106483435 0.45 ENSMUST00000164330.1
RIKEN cDNA 2010016I18 gene
chr1_+_119526125 0.45 ENSMUST00000183952.1
Transmembrane protein 185B
chr11_-_59571813 0.44 ENSMUST00000071943.2
olfactory receptor 222
chr13_-_90089556 0.43 ENSMUST00000022115.7
X-ray repair complementing defective repair in Chinese hamster cells 4
chr9_-_67832325 0.43 ENSMUST00000054500.5
C2 calcium-dependent domain containing 4A
chr14_-_78536762 0.42 ENSMUST00000123853.1
A kinase (PRKA) anchor protein 11
chr3_+_96697100 0.42 ENSMUST00000107077.3
protein inhibitor of activated STAT 3
chr8_+_94601928 0.41 ENSMUST00000060389.8
ENSMUST00000121101.1
ring finger and SPRY domain containing 1
chr14_-_78536854 0.41 ENSMUST00000022593.5
A kinase (PRKA) anchor protein 11
chr10_+_78574492 0.40 ENSMUST00000105384.3
ilvB (bacterial acetolactate synthase)-like
chr11_-_96075581 0.39 ENSMUST00000107686.1
ENSMUST00000107684.1
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c1 (subunit 9)
chr4_+_148039035 0.39 ENSMUST00000097788.4
5,10-methylenetetrahydrofolate reductase
chr11_-_96075655 0.38 ENSMUST00000090541.5
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c1 (subunit 9)
chr19_+_8819401 0.38 ENSMUST00000096753.3
heterogeneous nuclear ribonucleoprotein U-like 2
chr3_+_144570409 0.37 ENSMUST00000082437.3
selenoprotein
chr5_+_30869623 0.36 ENSMUST00000114716.1
transmembrane protein 214
chr7_-_16874845 0.35 ENSMUST00000181501.1
RIKEN cDNA 9330104G04 gene
chr6_-_22356176 0.34 ENSMUST00000081288.7
family with sequence similarity 3, member C
chr12_+_69241832 0.34 ENSMUST00000063445.6
kelch domain containing 1
chr6_-_22356068 0.33 ENSMUST00000163963.1
ENSMUST00000165576.1
family with sequence similarity 3, member C
chr3_+_96697076 0.32 ENSMUST00000162778.2
ENSMUST00000064900.9
protein inhibitor of activated STAT 3
chr10_+_111164794 0.32 ENSMUST00000105275.1
ENSMUST00000095310.1
oxysterol binding protein-like 8
chr17_+_35424842 0.31 ENSMUST00000174699.1
histocompatibility 2, Q region locus 6
chr5_+_30869579 0.31 ENSMUST00000046349.7
transmembrane protein 214
chr10_-_34418465 0.29 ENSMUST00000099973.3
ENSMUST00000105512.1
ENSMUST00000047885.7
5'-nucleotidase domain containing 1
chr11_+_5099406 0.29 ENSMUST00000134267.1
ENSMUST00000036320.5
ENSMUST00000150632.1
rhomboid domain containing 3
chr10_-_19014549 0.29 ENSMUST00000146388.1
tumor necrosis factor, alpha-induced protein 3
chr2_+_153875045 0.28 ENSMUST00000028983.2
BPI fold containing family B, member 2
chr11_+_100415722 0.27 ENSMUST00000107400.2
FK506 binding protein 10
chr7_-_31115227 0.25 ENSMUST00000168884.1
ENSMUST00000108102.2
hepsin
chr14_+_26638074 0.24 ENSMUST00000022429.2
ADP-ribosylation factor 4
chr13_-_90089513 0.24 ENSMUST00000160232.1
X-ray repair complementing defective repair in Chinese hamster cells 4
chr10_-_81060134 0.24 ENSMUST00000005067.5
small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
chr4_-_129742275 0.23 ENSMUST00000066257.5
KH domain containing, RNA binding, signal transduction associated 1
chr6_-_38299236 0.23 ENSMUST00000058524.2
zinc finger CCCH-type, antiviral 1-like
chr10_-_19015347 0.23 ENSMUST00000019997.4
tumor necrosis factor, alpha-induced protein 3
chrX_+_157818435 0.23 ENSMUST00000087157.4
kelch-like 34
chr1_+_75142775 0.23 ENSMUST00000097694.4
family with sequence similarity 134, member A
chr6_-_101377342 0.23 ENSMUST00000151175.1
PDZ domain containing RING finger 3
chr3_-_88177671 0.22 ENSMUST00000181837.1
RIKEN cDNA 1700113A16 gene
chr16_+_5050012 0.22 ENSMUST00000052449.5
ubinuclein 1
chr13_-_24206281 0.21 ENSMUST00000123076.1
leucine rich repeat containing 16A
chr5_+_63812447 0.21 ENSMUST00000081747.3
RIKEN cDNA 0610040J01 gene
chr14_+_26638237 0.20 ENSMUST00000112318.3
ADP-ribosylation factor 4
chr11_-_51756378 0.20 ENSMUST00000109092.1
ENSMUST00000064297.4
ENSMUST00000109097.2
Sec24 related gene family, member A (S. cerevisiae)
chr14_-_26638183 0.20 ENSMUST00000166902.1
RIKEN cDNA 4930570N19 gene
chr9_-_115310421 0.20 ENSMUST00000035010.8
STT3, subunit of the oligosaccharyltransferase complex, homolog B (S. cerevisiae)
chr4_+_44756553 0.19 ENSMUST00000107824.2
zinc finger, CCHC domain containing 7
chr11_-_5099223 0.19 ENSMUST00000079949.6
Ewing sarcoma breakpoint region 1
chr17_+_35424870 0.19 ENSMUST00000113879.3
histocompatibility 2, Q region locus 6
chr5_+_108268897 0.18 ENSMUST00000031190.4
down-regulator of transcription 1
chr4_+_44756609 0.17 ENSMUST00000143385.1
zinc finger, CCHC domain containing 7
chr10_-_119240006 0.16 ENSMUST00000020315.6
cullin associated and neddylation disassociated 1
chr3_-_89773221 0.16 ENSMUST00000038450.1
RIKEN cDNA 4632404H12 gene
chr7_+_30421724 0.15 ENSMUST00000108176.1
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, delta
chr19_+_6975048 0.15 ENSMUST00000070850.6
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr2_-_155473788 0.14 ENSMUST00000109670.1
ENSMUST00000123293.1
nuclear receptor coactivator 6
chr4_-_132075250 0.12 ENSMUST00000105970.1
ENSMUST00000105975.1
erythrocyte protein band 4.1
chr1_-_36683115 0.11 ENSMUST00000170295.1
ENSMUST00000114981.1
family with sequence similarity 178, member B
chr5_+_31054821 0.11 ENSMUST00000174367.1
ENSMUST00000170329.1
ENSMUST00000031049.6
carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
chr3_-_20155069 0.11 ENSMUST00000184552.1
ENSMUST00000178328.1
glycogenin
chr15_+_10714836 0.10 ENSMUST00000180604.1
RIKEN cDNA 4930556M19 gene
chr5_-_31154152 0.09 ENSMUST00000114632.1
ENSMUST00000114631.2
ENSMUST00000067186.6
ENSMUST00000137165.1
ENSMUST00000131391.1
ENSMUST00000141823.1
ENSMUST00000154241.1
MpV17 mitochondrial inner membrane protein
chrX_+_7822289 0.09 ENSMUST00000009875.4
potassium voltage-gated channel, Shal-related family, member 1
chr17_-_56074932 0.08 ENSMUST00000019722.5
UBX domain protein 6
chr5_-_100416115 0.08 ENSMUST00000182886.1
ENSMUST00000094578.4
Sec31 homolog A (S. cerevisiae)
chr11_+_70000578 0.08 ENSMUST00000019362.8
dishevelled 2, dsh homolog (Drosophila)
chr11_-_5099053 0.08 ENSMUST00000093365.5
ENSMUST00000073308.4
Ewing sarcoma breakpoint region 1
chr10_+_20148457 0.07 ENSMUST00000020173.8
microtubule-associated protein 7
chr9_-_106887000 0.07 ENSMUST00000055843.7
RNA binding motif protein 15B
chr11_-_5099036 0.06 ENSMUST00000102930.3
Ewing sarcoma breakpoint region 1
chr4_+_128654686 0.05 ENSMUST00000030588.6
ENSMUST00000136377.1
polyhomeotic-like 2 (Drosophila)
chr17_-_24163668 0.05 ENSMUST00000040735.5
amidohydrolase domain containing 2
chr10_+_61648552 0.05 ENSMUST00000020286.6
pyrophosphatase (inorganic) 1
chr11_-_55033398 0.04 ENSMUST00000108883.3
ENSMUST00000102727.2
annexin A6
chr5_+_31054766 0.04 ENSMUST00000013773.5
ENSMUST00000114646.1
carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
chr5_-_35679416 0.03 ENSMUST00000114233.2
HtrA serine peptidase 3
chr2_+_164833781 0.03 ENSMUST00000143780.1
cathepsin A

Network of associatons between targets according to the STRING database.

First level regulatory network of Creb3l2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 4.4 GO:0018992 germ-line sex determination(GO:0018992)
0.6 1.8 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.6 2.8 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.5 7.6 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.4 1.3 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.4 1.5 GO:1904453 regulation of hydrogen:potassium-exchanging ATPase activity(GO:1904451) positive regulation of hydrogen:potassium-exchanging ATPase activity(GO:1904453)
0.4 1.1 GO:0009446 putrescine biosynthetic process(GO:0009446)
0.3 1.4 GO:0035666 TRIF-dependent toll-like receptor signaling pathway(GO:0035666)
0.3 1.0 GO:0070625 zymogen granule exocytosis(GO:0070625)
0.3 0.8 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.2 0.9 GO:0070829 heterochromatin maintenance(GO:0070829)
0.2 1.1 GO:0006041 glucosamine metabolic process(GO:0006041)
0.2 0.8 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.2 0.8 GO:1903416 response to glycoside(GO:1903416)
0.2 1.3 GO:0006621 protein retention in ER lumen(GO:0006621)
0.2 3.1 GO:0006465 signal peptide processing(GO:0006465)
0.2 5.9 GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.2 0.7 GO:0010360 negative regulation of anion channel activity(GO:0010360)
0.2 0.5 GO:0034148 regulation of granuloma formation(GO:0002631) negative regulation of granuloma formation(GO:0002632) regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) tolerance induction to lipopolysaccharide(GO:0072573)
0.2 1.3 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904) regulation of pro-B cell differentiation(GO:2000973)
0.2 0.5 GO:0019859 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.1 1.2 GO:0002328 pro-B cell differentiation(GO:0002328)
0.1 1.3 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.1 1.1 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.1 1.0 GO:0032264 IMP salvage(GO:0032264)
0.1 0.6 GO:2000317 negative regulation of T-helper 17 type immune response(GO:2000317) negative regulation of T-helper 17 cell differentiation(GO:2000320)
0.1 1.0 GO:0015670 carbon dioxide transport(GO:0015670)
0.1 5.0 GO:1903146 regulation of mitophagy(GO:1903146)
0.1 0.3 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.1 1.3 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.1 0.5 GO:2000680 regulation of rubidium ion transport(GO:2000680)
0.1 3.9 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.1 1.2 GO:0014842 regulation of skeletal muscle satellite cell proliferation(GO:0014842)
0.1 0.3 GO:0034769 basement membrane disassembly(GO:0034769)
0.1 0.2 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.1 0.2 GO:0032241 positive regulation of nucleobase-containing compound transport(GO:0032241)
0.1 1.9 GO:0006817 phosphate ion transport(GO:0006817)
0.1 0.9 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.1 0.5 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.1 0.2 GO:0043686 co-translational protein modification(GO:0043686)
0.1 1.1 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.1 1.9 GO:1902175 regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902175)
0.1 1.0 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.1 1.0 GO:0060510 Type II pneumocyte differentiation(GO:0060510)
0.1 0.8 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.1 1.8 GO:0032292 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.1 1.8 GO:0060445 branching involved in salivary gland morphogenesis(GO:0060445)
0.0 0.7 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 0.5 GO:0051683 establishment of Golgi localization(GO:0051683)
0.0 0.8 GO:1903206 negative regulation of hydrogen peroxide-induced cell death(GO:1903206)
0.0 0.9 GO:0046653 tetrahydrofolate metabolic process(GO:0046653)
0.0 1.2 GO:0042036 negative regulation of cytokine biosynthetic process(GO:0042036)
0.0 0.4 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.0 1.4 GO:0006739 NADP metabolic process(GO:0006739)
0.0 0.9 GO:0001921 positive regulation of receptor recycling(GO:0001921)
0.0 0.8 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986) ATP hydrolysis coupled proton transport(GO:0015991)
0.0 0.6 GO:0009251 glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.0 0.1 GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.0 1.1 GO:0009409 response to cold(GO:0009409)
0.0 2.1 GO:0032024 positive regulation of insulin secretion(GO:0032024)
0.0 0.8 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.0 0.7 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.1 GO:0044340 canonical Wnt signaling pathway involved in regulation of cell proliferation(GO:0044340)
0.0 0.2 GO:0070245 positive regulation of thymocyte apoptotic process(GO:0070245)
0.0 1.9 GO:0000724 double-strand break repair via homologous recombination(GO:0000724) recombinational repair(GO:0000725)
0.0 0.5 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0 1.3 GO:0007030 Golgi organization(GO:0007030)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 7.6 GO:0005579 membrane attack complex(GO:0005579)
0.4 3.1 GO:0005787 signal peptidase complex(GO:0005787)
0.4 1.5 GO:0097574 lateral part of cell(GO:0097574) basolateral part of cell(GO:1990794) rod bipolar cell terminal bouton(GO:1990795)
0.3 1.1 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.2 1.2 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) DNA ligase IV complex(GO:0032807)
0.2 3.9 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.2 1.4 GO:0097342 ripoptosome(GO:0097342)
0.1 2.2 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 1.0 GO:0005796 Golgi lumen(GO:0005796)
0.1 0.5 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.1 0.8 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 4.3 GO:0031901 early endosome membrane(GO:0031901)
0.1 1.8 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.1 0.7 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.1 2.8 GO:0015030 Cajal body(GO:0015030)
0.1 0.8 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 1.9 GO:1990391 DNA repair complex(GO:1990391)
0.0 0.6 GO:0016342 catenin complex(GO:0016342)
0.0 0.5 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.9 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.5 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.3 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.8 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 1.0 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.2 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.8 GO:0008859 exoribonuclease II activity(GO:0008859)
0.6 1.9 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.3 1.3 GO:0046923 ER retention sequence binding(GO:0046923)
0.3 0.9 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.3 2.9 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.3 0.9 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.3 0.8 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.2 1.3 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.2 1.2 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.2 0.6 GO:0030617 transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity(GO:0030617)
0.2 3.9 GO:0001056 RNA polymerase III activity(GO:0001056)
0.2 0.8 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.2 1.5 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.2 0.6 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.1 0.8 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 1.0 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 0.7 GO:0051185 coenzyme transporter activity(GO:0051185)
0.1 2.1 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 0.8 GO:0008556 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556) steroid hormone binding(GO:1990239)
0.1 1.3 GO:0048038 quinone binding(GO:0048038)
0.1 1.0 GO:0015250 water channel activity(GO:0015250)
0.1 0.5 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.1 7.7 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.9 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.0 1.7 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.1 GO:0004088 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.0 0.2 GO:1904288 BAT3 complex binding(GO:1904288)
0.0 1.4 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.0 0.8 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.4 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.8 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.5 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 1.8 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.7 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 1.6 GO:0050661 NADP binding(GO:0050661)
0.0 0.8 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.0 1.1 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 1.1 GO:0008378 galactosyltransferase activity(GO:0008378)
0.0 0.7 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.5 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.3 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.5 GO:0016790 thiolester hydrolase activity(GO:0016790)
0.0 1.9 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.8 GO:0005109 frizzled binding(GO:0005109)
0.0 0.2 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.3 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 1.5 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 0.1 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.0 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.2 GO:0008143 poly(A) binding(GO:0008143)
0.0 2.2 GO:0008236 serine-type peptidase activity(GO:0008236)
0.0 0.7 GO:0005507 copper ion binding(GO:0005507)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 6.5 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 2.1 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.1 0.7 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 1.2 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 1.4 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 1.8 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 1.9 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 1.8 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 2.2 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.9 PID RAS PATHWAY Regulation of Ras family activation
0.0 1.2 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.5 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.6 PID ALK1 PATHWAY ALK1 signaling events
0.0 1.0 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.3 PID BARD1 PATHWAY BARD1 signaling events
0.0 1.1 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 7.6 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.2 5.9 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.2 3.9 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.2 3.1 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 1.4 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.1 1.0 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 1.1 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.1 1.2 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.1 1.1 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 1.0 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 0.9 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1 1.1 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.1 2.8 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 1.1 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.8 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 1.5 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.8 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.6 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 1.8 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 1.6 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.8 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.5 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.7 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 1.9 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.1 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.6 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 1.1 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.8 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.5 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.6 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 1.7 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events