Project

12D miR HR13_24

Navigation
Downloads

Results for E2f4

Z-value: 2.27

Motif logo

Transcription factors associated with E2f4

Gene Symbol Gene ID Gene Info
ENSMUSG00000014859.8 E2F transcription factor 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
E2f4mm10_v2_chr8_+_105297663_1052977420.701.7e-02Click!

Activity profile of E2f4 motif

Sorted Z-values of E2f4 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr19_+_6084983 7.83 ENSMUST00000025704.2
cell division cycle associated 5
chr4_+_134510999 7.49 ENSMUST00000105866.2
aurora kinase A and ninein interacting protein
chr8_-_53638945 7.02 ENSMUST00000047768.4
nei like 3 (E. coli)
chr18_-_34751502 6.70 ENSMUST00000060710.7
cell division cycle 25C
chr1_-_169531343 6.52 ENSMUST00000028000.7
NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr14_-_47418407 6.45 ENSMUST00000043296.3
discs, large (Drosophila) homolog-associated protein 5
chr6_+_124830217 6.40 ENSMUST00000131847.1
ENSMUST00000151674.1
cell division cycle associated 3
chr1_-_169531447 6.08 ENSMUST00000111368.1
NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr1_-_189688074 5.75 ENSMUST00000171929.1
ENSMUST00000165962.1
centromere protein F
chr17_-_25727364 5.24 ENSMUST00000170070.1
ENSMUST00000048054.7
CTF18, chromosome transmission fidelity factor 18
chr11_-_101551837 5.13 ENSMUST00000017290.4
breast cancer 1
chr10_-_88146867 4.54 ENSMUST00000164121.1
ENSMUST00000164803.1
ENSMUST00000168163.1
ENSMUST00000048518.9
PARP1 binding protein
chr12_+_117843873 4.51 ENSMUST00000176735.1
ENSMUST00000177339.1
cell division cycle associated 7 like
chr4_-_132345686 4.43 ENSMUST00000030726.6
regulator of chromosome condensation 1
chr13_-_73937761 4.39 ENSMUST00000022053.8
thyroid hormone receptor interactor 13
chr4_-_132345715 4.34 ENSMUST00000084250.4
regulator of chromosome condensation 1
chr4_-_116123618 4.32 ENSMUST00000102704.3
ENSMUST00000102705.3
RAD54 like (S. cerevisiae)
chr17_-_24251382 4.15 ENSMUST00000115390.3
cyclin F
chr14_-_87141206 4.03 ENSMUST00000022599.7
diaphanous homolog 3 (Drosophila)
chrX_+_164980592 3.97 ENSMUST00000101082.4
ENSMUST00000167446.1
ENSMUST00000057150.6
Fanconi anemia, complementation group B
chr9_+_106477269 3.63 ENSMUST00000047721.8
RRP9, small subunit (SSU) processome component, homolog (yeast)
chr9_+_107950952 3.43 ENSMUST00000049348.3
TRAF-interacting protein
chr14_-_87141114 3.42 ENSMUST00000168889.1
diaphanous homolog 3 (Drosophila)
chr4_+_11558914 3.40 ENSMUST00000178703.1
ENSMUST00000095145.5
ENSMUST00000108306.2
ENSMUST00000070755.6
RAD54 homolog B (S. cerevisiae)
chr16_-_90727329 3.37 ENSMUST00000099554.4
MIS18 kinetochore protein homolog A (S. pombe)
chr18_+_34751803 3.21 ENSMUST00000181453.1
ENSMUST00000181641.1
RIKEN cDNA 2010110K18 gene
chr1_-_33669745 3.09 ENSMUST00000027312.9
DNA primase, p58 subunit
chr7_-_92874196 3.01 ENSMUST00000032877.9
RIKEN cDNA 4632434I11 gene
chr2_+_163054682 2.82 ENSMUST00000018005.3
myeloblastosis oncogene-like 2
chr11_-_6606053 2.74 ENSMUST00000045713.3
NAC alpha domain containing
chr5_-_112228934 2.74 ENSMUST00000181535.2
myocardial infarction associated transcript (non-protein coding)
chr5_+_33721724 2.69 ENSMUST00000067150.7
ENSMUST00000169212.2
ENSMUST00000114411.2
ENSMUST00000164207.3
fibroblast growth factor receptor 3
chr6_+_113531675 2.44 ENSMUST00000036340.5
ENSMUST00000101051.2
Fanconi anemia, complementation group D2
chr1_-_57377476 2.25 ENSMUST00000181949.1
RIKEN cDNA 4930558J18 gene
chr7_-_127260677 2.23 ENSMUST00000035276.4
dCTP pyrophosphatase 1
chr11_+_98907801 2.15 ENSMUST00000092706.6
cell division cycle 6
chr7_-_38107490 1.99 ENSMUST00000108023.3
cyclin E1
chr15_-_76639840 1.87 ENSMUST00000166974.1
ENSMUST00000168185.1
tonsoku-like, DNA repair protein
chr6_-_56704673 1.87 ENSMUST00000170382.2
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr18_+_56707725 1.83 ENSMUST00000025486.8
lamin B1
chr9_-_123678782 1.83 ENSMUST00000170591.1
ENSMUST00000171647.1
solute carrier family 6 (neurotransmitter transporter), member 20A
chr8_+_18595131 1.82 ENSMUST00000039412.8
microcephaly, primary autosomal recessive 1
chrX_-_8074720 1.80 ENSMUST00000115636.3
ENSMUST00000115638.3
suppressor of variegation 3-9 homolog 1 (Drosophila)
chr15_+_55307743 1.76 ENSMUST00000023053.5
ENSMUST00000110221.2
ENSMUST00000110217.3
collagen, type XIV, alpha 1
chr10_+_127677064 1.72 ENSMUST00000118612.1
ENSMUST00000048099.4
transmembrane protein 194
chr2_+_30286406 1.72 ENSMUST00000138666.1
ENSMUST00000113634.2
nucleoporin 188
chr4_-_133967235 1.60 ENSMUST00000123234.1
high mobility group nucleosomal binding domain 2
chr1_+_157412352 1.58 ENSMUST00000061537.5
RIKEN cDNA 2810025M15 gene
chr5_+_130257029 1.56 ENSMUST00000100662.3
ENSMUST00000040213.6
tRNA-yW synthesizing protein 1 homolog (S. cerevisiae)
chr10_-_117792663 1.55 ENSMUST00000167943.1
ENSMUST00000064848.5
nucleoporin 107
chr10_+_88146992 1.54 ENSMUST00000052355.7
nucleoporin 37
chr5_+_88764983 1.48 ENSMUST00000031311.9
deoxycytidine kinase
chr10_+_88147061 1.45 ENSMUST00000169309.1
nucleoporin 37
chr5_-_138172383 1.44 ENSMUST00000000505.9
minichromosome maintenance deficient 7 (S. cerevisiae)
chr11_+_16951371 1.44 ENSMUST00000109635.1
ENSMUST00000061327.1
F-box protein 48
chr8_+_124023394 1.41 ENSMUST00000034457.8
URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
chr7_+_97371604 1.41 ENSMUST00000098300.4
asparagine-linked glycosylation 8 (alpha-1,3-glucosyltransferase)
chr5_-_138171813 1.37 ENSMUST00000155902.1
ENSMUST00000148879.1
minichromosome maintenance deficient 7 (S. cerevisiae)
chr9_+_72438519 1.30 ENSMUST00000184604.1
meiosis-specific nuclear structural protein 1
chr8_+_18595526 1.26 ENSMUST00000146819.1
microcephaly, primary autosomal recessive 1
chr19_+_46075842 1.20 ENSMUST00000165017.1
nucleolar and coiled-body phosphoprotein 1
chr9_+_44134562 1.19 ENSMUST00000034650.8
ENSMUST00000098852.2
melanoma cell adhesion molecule
chrX_+_8271381 1.17 ENSMUST00000033512.4
solute carrier family 38, member 5
chr2_-_166713758 1.15 ENSMUST00000036719.5
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
chr4_-_133967296 1.15 ENSMUST00000105893.1
high mobility group nucleosomal binding domain 2
chr18_-_60848911 1.15 ENSMUST00000177172.1
ENSMUST00000175934.1
ENSMUST00000176630.1
Treacher Collins Franceschetti syndrome 1, homolog
chr19_+_8735808 1.14 ENSMUST00000049424.9
WD repeat domain 74
chr1_+_179803376 1.12 ENSMUST00000097454.2
predicted gene 10518
chr2_+_181319714 1.12 ENSMUST00000098971.4
ENSMUST00000054622.8
ENSMUST00000108814.1
ENSMUST00000048608.9
ENSMUST00000108815.1
regulator of telomere elongation helicase 1
chrX_+_8271133 1.12 ENSMUST00000127103.1
ENSMUST00000115591.1
solute carrier family 38, member 5
chrX_+_8271642 1.08 ENSMUST00000115590.1
solute carrier family 38, member 5
chr14_-_54517353 1.08 ENSMUST00000023873.5
protein arginine N-methyltransferase 5
chr14_+_70555900 1.08 ENSMUST00000163060.1
hairless
chr14_+_55578123 1.07 ENSMUST00000174484.1
proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
chr7_-_16285454 1.07 ENSMUST00000174270.1
coiled-coil domain containing 9
chr5_-_33652339 1.04 ENSMUST00000075670.6
stem-loop binding protein
chr2_-_3512746 1.02 ENSMUST00000056700.7
ENSMUST00000027961.5
heat shock protein 14
heat shock protein 14
chr4_-_133967893 1.00 ENSMUST00000100472.3
ENSMUST00000136327.1
high mobility group nucleosomal binding domain 2
chr12_+_99884498 0.98 ENSMUST00000153627.1
tyrosyl-DNA phosphodiesterase 1
chr4_-_59783800 0.98 ENSMUST00000107526.1
ENSMUST00000095063.4
INTS3 and NABP interacting protein
chrY_+_90784738 0.95 ENSMUST00000179483.1
erythroid differentiation regulator 1
chr11_+_87405049 0.94 ENSMUST00000060835.5
testis expressed gene 14
chr3_+_88553716 0.93 ENSMUST00000008748.6
ubiquilin 4
chr17_+_34982099 0.92 ENSMUST00000007266.7
LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr4_-_132463873 0.91 ENSMUST00000102567.3
mediator of RNA polymerase II transcription, subunit 18 homolog (yeast)
chr17_+_34982154 0.86 ENSMUST00000173004.1
LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr17_+_50698525 0.85 ENSMUST00000061681.7
predicted gene 7334
chrX_+_38600626 0.85 ENSMUST00000000365.2
malignant T cell amplified sequence 1
chr14_-_33447142 0.84 ENSMUST00000111944.3
ENSMUST00000022504.5
ENSMUST00000111945.2
mitogen-activated protein kinase 8
chr1_-_179803625 0.83 ENSMUST00000027768.7
AT hook containing transcription factor 1
chr4_-_3835595 0.81 ENSMUST00000138502.1
ribosomal protein S20
chr17_-_66101466 0.78 ENSMUST00000024909.8
ENSMUST00000147484.1
ENSMUST00000143987.1
NADH dehydrogenase (ubiquinone) flavoprotein 2
chr2_+_181319806 0.78 ENSMUST00000153112.1
regulator of telomere elongation helicase 1
chr12_-_118198917 0.77 ENSMUST00000084806.6
dynein, axonemal, heavy chain 11
chr2_-_172940299 0.73 ENSMUST00000009143.7
bone morphogenetic protein 7
chr17_-_28350747 0.71 ENSMUST00000080572.7
ENSMUST00000156862.1
TEA domain family member 3
chr9_+_72438534 0.71 ENSMUST00000034746.8
meiosis-specific nuclear structural protein 1
chr15_+_57912199 0.70 ENSMUST00000022992.6
TBC1 domain family, member 31
chr19_-_5366626 0.69 ENSMUST00000025762.8
barrier to autointegration factor 1
chr2_+_126152141 0.65 ENSMUST00000170908.1
DTW domain containing 1
chr4_-_133967953 0.64 ENSMUST00000102553.4
high mobility group nucleosomal binding domain 2
chr17_+_87975044 0.64 ENSMUST00000005503.3
mutS homolog 6 (E. coli)
chr17_+_34981847 0.61 ENSMUST00000114011.4
LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr3_-_107969162 0.61 ENSMUST00000004136.8
ENSMUST00000106678.1
glutathione S-transferase, mu 3
chr5_+_30232581 0.60 ENSMUST00000145167.1
ethanolaminephosphotransferase 1 (CDP-ethanolamine-specific)
chr5_-_112228900 0.59 ENSMUST00000182509.1
myocardial infarction associated transcript (non-protein coding)
chr5_-_33652296 0.54 ENSMUST00000151081.1
ENSMUST00000101354.3
stem-loop binding protein
chr9_+_57708534 0.50 ENSMUST00000043990.7
ENSMUST00000142807.1
enhancer of mRNA decapping 3 homolog (S. cerevisiae)
chr18_-_39490649 0.49 ENSMUST00000115567.1
nuclear receptor subfamily 3, group C, member 1
chr7_+_58658181 0.48 ENSMUST00000168747.1
ATPase, class V, type 10A
chr7_+_45783686 0.47 ENSMUST00000118564.1
ENSMUST00000133428.1
lemur tyrosine kinase 3
chr7_+_6383310 0.46 ENSMUST00000081022.7
zinc finger protein 28
chr13_-_69533839 0.45 ENSMUST00000044081.7
PAP associated domain containing 7
chr4_+_108834601 0.44 ENSMUST00000030296.8
thioredoxin domain containing 12 (endoplasmic reticulum)
chr1_+_57377593 0.42 ENSMUST00000042734.2
RIKEN cDNA 1700066M21 gene
chr1_+_52630692 0.41 ENSMUST00000165859.1
transmembrane protein 194B
chr1_+_86303221 0.38 ENSMUST00000113306.2
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7
chr7_+_45783883 0.38 ENSMUST00000072580.5
lemur tyrosine kinase 3
chr11_-_106999369 0.38 ENSMUST00000106768.1
ENSMUST00000144834.1
karyopherin (importin) alpha 2
chr7_+_24884651 0.36 ENSMUST00000153451.2
ENSMUST00000108429.1
ribosomal protein S19
chr7_+_24884611 0.32 ENSMUST00000108428.1
ribosomal protein S19
chr5_-_25705791 0.32 ENSMUST00000030773.7
X-ray repair complementing defective repair in Chinese hamster cells 2
chr12_+_106010263 0.30 ENSMUST00000021539.8
ENSMUST00000085026.4
ENSMUST00000072040.5
vaccinia related kinase 1
chrX_+_105079761 0.30 ENSMUST00000119477.1
polysaccharide biosynthesis domain containing 1
chr10_-_81427114 0.29 ENSMUST00000078185.7
ENSMUST00000020461.8
ENSMUST00000105321.3
nuclear factor I/C
chr7_-_16286010 0.27 ENSMUST00000145519.2
coiled-coil domain containing 9
chrX_+_105079735 0.26 ENSMUST00000033577.4
polysaccharide biosynthesis domain containing 1
chr4_+_44004438 0.24 ENSMUST00000107846.3
clathrin, light polypeptide (Lca)
chr2_+_140395446 0.23 ENSMUST00000110061.1
MACRO domain containing 2
chr11_+_119602981 0.21 ENSMUST00000026671.6
regulatory associated protein of MTOR, complex 1
chr15_-_98677451 0.21 ENSMUST00000120997.1
ENSMUST00000109149.2
ENSMUST00000003451.4
Rho family GTPase 1
chr15_+_12824841 0.20 ENSMUST00000090292.5
drosha, ribonuclease type III
chr11_-_106999482 0.19 ENSMUST00000018506.6
karyopherin (importin) alpha 2
chrX_-_12762069 0.19 ENSMUST00000096495.4
ENSMUST00000076016.5
mediator complex subunit 14
chr3_+_121953213 0.17 ENSMUST00000037958.7
ENSMUST00000128366.1
Rho GTPase activating protein 29
chr4_-_43562397 0.16 ENSMUST00000030187.7
talin 1
chr2_+_101678403 0.16 ENSMUST00000004949.7
TNF receptor-associated factor 6
chr15_+_12824815 0.15 ENSMUST00000169061.1
drosha, ribonuclease type III
chr7_+_126781483 0.15 ENSMUST00000172352.1
ENSMUST00000094037.4
T-box 6
chr8_-_123158268 0.13 ENSMUST00000000755.7
sulfotransferase family 5A, member 1
chr12_-_87147883 0.13 ENSMUST00000037788.4
protein-O-mannosyltransferase 2
chr6_-_148831395 0.13 ENSMUST00000145960.1
importin 8
chr2_+_174076296 0.12 ENSMUST00000155000.1
ENSMUST00000134876.1
ENSMUST00000147038.1
syntaxin 16
chr12_-_4233958 0.10 ENSMUST00000111169.3
ENSMUST00000020981.5
centromere protein O
chr17_-_87025353 0.10 ENSMUST00000024957.6
phosphatidylinositol glycan anchor biosynthesis, class F
chr1_+_132007606 0.09 ENSMUST00000086556.5
ELK4, member of ETS oncogene family
chr11_-_88864534 0.09 ENSMUST00000018572.4
A kinase (PRKA) anchor protein 1
chr5_+_144100387 0.09 ENSMUST00000041804.7
lemur tyrosine kinase 2
chr9_-_44134481 0.08 ENSMUST00000180670.1
predicted gene 10687
chr8_-_64849818 0.07 ENSMUST00000034017.7
kelch-like 2, Mayven
chr14_+_31019159 0.07 ENSMUST00000112094.1
ENSMUST00000144009.1
polybromo 1
chr11_+_108425192 0.06 ENSMUST00000150863.2
ENSMUST00000061287.5
ENSMUST00000149683.2
centrosomal protein 112
chr17_-_28350600 0.06 ENSMUST00000114799.1
TEA domain family member 3
chr7_+_97579868 0.03 ENSMUST00000042399.7
ENSMUST00000107153.1
remodeling and spacing factor 1
chr17_+_88440711 0.03 ENSMUST00000112238.2
ENSMUST00000155640.1
forkhead box N2
chr10_-_91123955 0.01 ENSMUST00000164505.1
ENSMUST00000170810.1
ENSMUST00000076694.6
solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 3

Network of associatons between targets according to the STRING database.

First level regulatory network of E2f4

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 7.8 GO:0071922 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
1.7 5.1 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
1.0 4.0 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.9 2.7 GO:0061144 alveolar secondary septum development(GO:0061144)
0.8 3.1 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.6 1.8 GO:0031660 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662)
0.6 4.2 GO:0000320 re-entry into mitotic cell cycle(GO:0000320)
0.6 5.2 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.6 3.4 GO:0061641 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.6 2.2 GO:0009223 pyrimidine nucleotide catabolic process(GO:0006244) pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
0.5 4.4 GO:0007144 female meiosis I(GO:0007144)
0.5 1.6 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.5 3.1 GO:0060623 regulation of chromosome condensation(GO:0060623)
0.5 1.9 GO:1904430 mitotic telomere maintenance via semi-conservative replication(GO:1902990) negative regulation of t-circle formation(GO:1904430)
0.5 1.8 GO:0035524 proline transmembrane transport(GO:0035524)
0.4 4.5 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.4 1.5 GO:0046125 pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.4 13.5 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.3 1.7 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
0.3 2.8 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.3 8.4 GO:0008340 determination of adult lifespan(GO:0008340)
0.3 1.1 GO:0060161 positive regulation of dopamine receptor signaling pathway(GO:0060161)
0.3 3.4 GO:0015816 glycine transport(GO:0015816)
0.2 2.4 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.2 0.7 GO:1900106 hyaluranon cable assembly(GO:0036118) kidney mesenchyme morphogenesis(GO:0072131) metanephric mesenchyme morphogenesis(GO:0072133) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.2 3.4 GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway(GO:0010804)
0.2 6.7 GO:1902751 positive regulation of cell cycle G2/M phase transition(GO:1902751)
0.2 0.8 GO:0002188 translation reinitiation(GO:0002188)
0.2 0.8 GO:2000017 positive regulation of determination of dorsal identity(GO:2000017)
0.2 1.9 GO:0007000 nucleolus organization(GO:0007000)
0.2 2.4 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.2 3.3 GO:0035881 amacrine cell differentiation(GO:0035881)
0.2 0.9 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.2 1.8 GO:0036123 histone H3-K9 dimethylation(GO:0036123)
0.2 1.6 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.1 7.0 GO:0006284 base-excision repair(GO:0006284)
0.1 4.1 GO:0006270 DNA replication initiation(GO:0006270)
0.1 5.8 GO:0051310 metaphase plate congression(GO:0051310)
0.1 11.6 GO:0051225 spindle assembly(GO:0051225)
0.1 0.9 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.1 1.9 GO:0031297 replication fork processing(GO:0031297)
0.1 3.7 GO:0040034 regulation of development, heterochronic(GO:0040034)
0.1 0.3 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.1 1.2 GO:0014029 neural crest formation(GO:0014029)
0.1 6.5 GO:0007051 spindle organization(GO:0007051)
0.1 0.8 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.1 1.3 GO:0070986 left/right axis specification(GO:0070986)
0.1 1.4 GO:0006490 oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.1 0.7 GO:0015074 DNA integration(GO:0015074)
0.1 0.5 GO:1900170 negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
0.1 0.8 GO:0003356 regulation of cilium beat frequency(GO:0003356)
0.1 0.3 GO:0043987 histone H3-S10 phosphorylation(GO:0043987)
0.1 1.0 GO:0000012 single strand break repair(GO:0000012)
0.1 0.8 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.1 0.5 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.1 0.4 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.1 1.1 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.1 1.8 GO:0061050 regulation of cell growth involved in cardiac muscle cell development(GO:0061050)
0.0 0.1 GO:1904100 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.0 0.8 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 1.2 GO:0019884 antigen processing and presentation of exogenous antigen(GO:0019884)
0.0 0.2 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.2 GO:0071233 response to leucine(GO:0043201) cellular response to leucine(GO:0071233)
0.0 0.2 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 1.2 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.0 0.1 GO:0014043 negative regulation of neuron maturation(GO:0014043)
0.0 0.6 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 1.2 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.2 GO:0016322 neuron remodeling(GO:0016322)
0.0 1.0 GO:0001825 blastocyst formation(GO:0001825)
0.0 0.1 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.0 1.6 GO:0008033 tRNA processing(GO:0008033)
0.0 0.8 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 3.0 GO:0042254 ribosome biogenesis(GO:0042254)
0.0 0.8 GO:0010923 negative regulation of phosphatase activity(GO:0010923)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 12.6 GO:0031262 Ndc80 complex(GO:0031262)
0.9 7.8 GO:0008278 cohesin complex(GO:0008278)
0.9 5.1 GO:0070531 BRCA1-A complex(GO:0070531)
0.6 1.9 GO:0035101 FACT complex(GO:0035101)
0.6 3.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.6 4.3 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.6 5.2 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.6 2.8 GO:0031523 Myb complex(GO:0031523)
0.5 5.8 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.5 3.6 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.5 5.4 GO:0031080 nuclear pore outer ring(GO:0031080)
0.4 4.0 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.4 1.8 GO:0033553 rDNA heterochromatin(GO:0033553)
0.3 1.7 GO:0044611 nuclear pore inner ring(GO:0044611)
0.3 6.4 GO:0031616 spindle pole centrosome(GO:0031616)
0.3 1.1 GO:0008537 proteasome activator complex(GO:0008537)
0.3 1.8 GO:0005638 lamin filament(GO:0005638)
0.2 4.1 GO:0001673 male germ cell nucleus(GO:0001673)
0.2 1.6 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.2 2.8 GO:0042555 MCM complex(GO:0042555)
0.2 1.0 GO:0070876 SOSS complex(GO:0070876)
0.2 1.1 GO:0070847 core mediator complex(GO:0070847)
0.1 1.1 GO:0034709 methylosome(GO:0034709)
0.1 0.4 GO:1903095 microprocessor complex(GO:0070877) ribonuclease III complex(GO:1903095)
0.1 0.9 GO:0031595 nuclear proteasome complex(GO:0031595)
0.1 0.6 GO:0032300 mismatch repair complex(GO:0032300)
0.1 9.6 GO:0000922 spindle pole(GO:0000922)
0.1 0.2 GO:0099631 postsynaptic endocytic zone cytoplasmic component(GO:0099631)
0.1 1.8 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.3 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.1 4.2 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 2.3 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 5.9 GO:0000793 condensed chromosome(GO:0000793)
0.0 1.1 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 2.0 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 1.2 GO:0015030 Cajal body(GO:0015030)
0.0 4.5 GO:0001650 fibrillar center(GO:0001650)
0.0 3.7 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 1.4 GO:0016235 aggresome(GO:0016235)
0.0 2.0 GO:0005882 intermediate filament(GO:0005882)
0.0 0.8 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 3.1 GO:0000775 chromosome, centromeric region(GO:0000775)
0.0 0.2 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.8 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.8 GO:0030286 dynein complex(GO:0030286)
0.0 10.0 GO:0048471 perinuclear region of cytoplasm(GO:0048471)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 8.8 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
1.4 7.0 GO:0000405 bubble DNA binding(GO:0000405)
0.5 1.6 GO:0071207 histone pre-mRNA stem-loop binding(GO:0071207)
0.5 3.4 GO:0015616 DNA translocase activity(GO:0015616)
0.5 5.2 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.5 1.4 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.5 3.6 GO:0034511 U3 snoRNA binding(GO:0034511)
0.4 4.3 GO:0036310 annealing helicase activity(GO:0036310)
0.4 1.2 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.4 1.5 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.3 2.7 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.3 2.8 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.3 3.4 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.3 1.1 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.3 1.8 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.2 1.8 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.2 2.2 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.2 0.6 GO:0032142 guanine/thymine mispair binding(GO:0032137) single guanine insertion binding(GO:0032142)
0.2 0.8 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.2 5.8 GO:0070840 dynein complex binding(GO:0070840)
0.1 0.4 GO:0019153 protein-disulfide reductase (glutathione) activity(GO:0019153)
0.1 4.3 GO:0070182 DNA polymerase binding(GO:0070182)
0.1 6.7 GO:0050699 WW domain binding(GO:0050699)
0.1 1.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 3.3 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 3.1 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 1.6 GO:0010181 FMN binding(GO:0010181)
0.1 0.5 GO:0038049 glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.1 2.4 GO:0017160 Ral GTPase binding(GO:0017160)
0.1 4.8 GO:0003684 damaged DNA binding(GO:0003684)
0.1 2.8 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.1 0.2 GO:0001156 TFIIIC-class transcription factor binding(GO:0001156)
0.1 0.4 GO:0032296 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.1 1.8 GO:0008432 JUN kinase binding(GO:0008432)
0.1 1.1 GO:0042809 vitamin D receptor binding(GO:0042809)
0.1 0.4 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.1 0.7 GO:0070700 BMP receptor binding(GO:0070700)
0.1 0.3 GO:0000150 recombinase activity(GO:0000150)
0.1 2.0 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 0.3 GO:0035184 nucleosomal histone binding(GO:0031493) histone threonine kinase activity(GO:0035184)
0.0 1.2 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.8 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.8 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.7 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.1 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 4.7 GO:0004721 phosphoprotein phosphatase activity(GO:0004721)
0.0 0.5 GO:0016891 endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891)
0.0 0.2 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.6 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.9 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 7.8 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 0.2 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.6 GO:0004364 glutathione transferase activity(GO:0004364)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 13.9 PID ATM PATHWAY ATM pathway
0.2 6.4 PID AURORA A PATHWAY Aurora A signaling
0.2 4.0 PID FANCONI PATHWAY Fanconi anemia pathway
0.2 7.6 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.1 5.0 PID ATR PATHWAY ATR signaling pathway
0.1 8.3 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.1 0.7 PID ALK2 PATHWAY ALK2 signaling events
0.1 3.9 PID E2F PATHWAY E2F transcription factor network
0.0 1.9 ST GAQ PATHWAY G alpha q Pathway
0.0 1.8 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 1.8 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 2.7 PID FGF PATHWAY FGF signaling pathway
0.0 0.8 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 1.8 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 1.6 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 0.6 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.0 0.2 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 6.7 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.5 11.5 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.3 3.1 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.3 4.8 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.3 7.0 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.2 6.3 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.2 2.8 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.2 2.7 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.1 1.6 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.1 8.8 REACTOME LATE PHASE OF HIV LIFE CYCLE Genes involved in Late Phase of HIV Life Cycle
0.1 8.9 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 0.7 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1 1.5 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 3.4 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 3.1 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1 1.0 REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS Genes involved in NRIF signals cell death from the nucleus
0.1 1.1 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.1 1.8 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.1 0.4 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 1.4 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 1.0 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair
0.0 0.6 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 1.5 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.4 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 1.1 REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.0 0.8 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.5 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 1.1 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 1.1 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.2 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.4 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 1.2 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.2 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.8 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.5 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases