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12D miR HR13_24

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Results for Pbx1_Pbx3

Z-value: 0.81

Motif logo

Transcription factors associated with Pbx1_Pbx3

Gene Symbol Gene ID Gene Info
ENSMUSG00000052534.9 pre B cell leukemia homeobox 1
ENSMUSG00000038718.9 pre B cell leukemia homeobox 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Pbx3mm10_v2_chr2_-_34372004_343720440.422.0e-01Click!
Pbx1mm10_v2_chr1_-_168431896_1684319050.274.3e-01Click!

Activity profile of Pbx1_Pbx3 motif

Sorted Z-values of Pbx1_Pbx3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr8_+_122848367 0.84 ENSMUST00000034443.5
cadherin 15
chr19_-_9899450 0.82 ENSMUST00000025562.7
inner centromere protein
chr11_+_98348404 0.77 ENSMUST00000078694.6
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr11_-_70229677 0.55 ENSMUST00000153449.1
ENSMUST00000000326.5
B cell CLL/lymphoma 6, member B
chr11_-_87108656 0.54 ENSMUST00000051395.8
proline rich 11
chr9_+_106281061 0.52 ENSMUST00000072206.6
POC1 centriolar protein homolog A (Chlamydomonas)
chr4_-_43523388 0.52 ENSMUST00000107913.3
ENSMUST00000030184.5
tropomyosin 2, beta
chr11_+_100334407 0.50 ENSMUST00000017309.1
gastrin
chr3_+_37639945 0.49 ENSMUST00000108109.1
ENSMUST00000038569.1
sprouty homolog 1 (Drosophila)
chr4_-_43523595 0.49 ENSMUST00000107914.3
tropomyosin 2, beta
chr4_+_11579647 0.47 ENSMUST00000180239.1
fibrinogen silencer binding protein
chr3_+_37639985 0.47 ENSMUST00000108107.1
sprouty homolog 1 (Drosophila)
chr4_-_43523746 0.47 ENSMUST00000150592.1
tropomyosin 2, beta
chr7_-_30450864 0.46 ENSMUST00000170152.1
kin of IRRE like 2 (Drosophila)
chr12_+_38780284 0.45 ENSMUST00000162563.1
ENSMUST00000161164.1
ENSMUST00000160996.1
ets variant gene 1
chr9_-_124424154 0.44 ENSMUST00000180270.1
protein phosphatase 2 (formerly 2A), regulatory subunit B'', delta
chr9_-_21760275 0.42 ENSMUST00000098942.4
SPC24, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr1_-_183147461 0.40 ENSMUST00000171366.1
dispatched homolog 1 (Drosophila)
chr9_+_122951051 0.39 ENSMUST00000040717.5
kinesin family member 15
chr8_+_125730005 0.37 ENSMUST00000143504.1
nucleoside-triphosphatase, cancer-related
chr11_+_87109221 0.36 ENSMUST00000020794.5
spindle and kinetochore associated complex subunit 2
chr16_+_22918378 0.34 ENSMUST00000170805.1
fetuin beta
chr14_+_99046406 0.33 ENSMUST00000022656.6
bora, aurora kinase A activator
chrX_-_109013389 0.33 ENSMUST00000033597.8
high-mobility group nucleosome binding domain 5
chr12_-_103863551 0.31 ENSMUST00000085056.6
ENSMUST00000072876.5
ENSMUST00000124717.1
serine (or cysteine) peptidase inhibitor, clade A, member 1A
chr5_-_41764493 0.31 ENSMUST00000060820.6
NK3 homeobox 2
chr15_-_8099182 0.29 ENSMUST00000045766.6
WD repeat domain 70
chr7_+_141475459 0.28 ENSMUST00000138092.1
ENSMUST00000146305.1
tetraspanin 4
chr7_-_18910377 0.27 ENSMUST00000139077.1
coiled-coil domain containing 61
chr11_-_58626044 0.26 ENSMUST00000070804.2
olfactory receptor 323
chr3_-_53657339 0.26 ENSMUST00000091137.4
Fras1 related extracellular matrix protein 2
chr11_-_80080928 0.26 ENSMUST00000103233.3
ENSMUST00000061283.8
cytokine receptor-like factor 3
chr11_-_96005872 0.26 ENSMUST00000013559.2
insulin-like growth factor 2 mRNA binding protein 1
chr14_-_48667508 0.25 ENSMUST00000144465.1
ENSMUST00000133479.1
ENSMUST00000119070.1
ENSMUST00000152018.1
orthodenticle homolog 2 (Drosophila)
chrX_-_60893430 0.25 ENSMUST00000135107.2
SRY-box containing gene 3
chr2_-_114052804 0.24 ENSMUST00000090269.6
actin, alpha, cardiac muscle 1
chr5_-_100500592 0.24 ENSMUST00000149714.1
ENSMUST00000046154.5
lin-54 homolog (C. elegans)
chr17_-_50094277 0.24 ENSMUST00000113195.1
raftlin lipid raft linker 1
chr13_+_15463837 0.24 ENSMUST00000110510.3
GLI-Kruppel family member GLI3
chr7_-_25005895 0.23 ENSMUST00000102858.3
ENSMUST00000080882.6
ATPase, Na+/K+ transporting, alpha 3 polypeptide
chrX_+_110814390 0.23 ENSMUST00000078229.3
POU domain, class 3, transcription factor 4
chr3_-_8667033 0.23 ENSMUST00000042412.3
hairy/enhancer-of-split related with YRPW motif 1
chr4_+_42949814 0.23 ENSMUST00000037872.3
ENSMUST00000098112.2
DnaJ (Hsp40) homolog, subfamily B, member 5
chr8_-_107403197 0.23 ENSMUST00000003947.8
NAD(P)H dehydrogenase, quinone 1
chr5_-_51553896 0.23 ENSMUST00000132734.1
peroxisome proliferative activated receptor, gamma, coactivator 1 alpha
chr11_-_115027012 0.22 ENSMUST00000100240.2
predicted gene 11710
chr15_-_79742518 0.22 ENSMUST00000089311.4
ENSMUST00000046259.7
Sad1 and UNC84 domain containing 2
chr5_+_104202609 0.21 ENSMUST00000066708.5
dentin matrix protein 1
chr5_-_115436508 0.21 ENSMUST00000078701.3
RIKEN cDNA 4930430O22 gene
chr15_-_79742493 0.21 ENSMUST00000100439.3
Sad1 and UNC84 domain containing 2
chr7_+_141475240 0.19 ENSMUST00000026585.7
tetraspanin 4
chr17_-_70853482 0.19 ENSMUST00000118283.1
TGFB-induced factor homeobox 1
chr2_-_125506385 0.19 ENSMUST00000028633.6
fibrillin 1
chr6_-_49214954 0.19 ENSMUST00000031838.7
insulin-like growth factor 2 mRNA binding protein 3
chr10_-_111997204 0.18 ENSMUST00000074805.5
GLI pathogenesis-related 1 (glioma)
chr2_-_174464063 0.18 ENSMUST00000016396.7
ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit
chr11_-_114989854 0.18 ENSMUST00000045075.2
CD300 molecule-like family member d
chr11_+_23256001 0.18 ENSMUST00000020538.6
ENSMUST00000109551.1
ENSMUST00000102870.1
ENSMUST00000102869.1
exportin 1, CRM1 homolog (yeast)
chr17_+_35533194 0.18 ENSMUST00000025273.8
psoriasis susceptibility 1 candidate 2 (human)
chr2_-_165852149 0.18 ENSMUST00000109258.3
zinc finger, MYND-type containing 8
chrX_-_8074720 0.18 ENSMUST00000115636.3
ENSMUST00000115638.3
suppressor of variegation 3-9 homolog 1 (Drosophila)
chr6_+_108660772 0.18 ENSMUST00000163617.1
basic helix-loop-helix family, member e40
chr18_-_77047243 0.18 ENSMUST00000137354.1
ENSMUST00000137498.1
katanin p60 subunit A-like 2
chr2_+_163820832 0.17 ENSMUST00000029188.7
WNT1 inducible signaling pathway protein 2
chr11_-_100441795 0.17 ENSMUST00000107398.1
5'-nucleotidase, cytosolic IIIB
chr13_+_72628831 0.17 ENSMUST00000169028.1
Iroquois related homeobox 2 (Drosophila)
chr11_+_84179852 0.17 ENSMUST00000136463.2
acetyl-Coenzyme A carboxylase alpha
chr5_-_67427794 0.16 ENSMUST00000169190.1
BEN domain containing 4
chr9_+_96258697 0.16 ENSMUST00000179416.1
transcription factor Dp 2
chr10_-_81600857 0.16 ENSMUST00000151858.1
ENSMUST00000142948.1
ENSMUST00000072020.2
transducin-like enhancer of split 6, homolog of Drosophila E(spl)
chr8_-_115707778 0.16 ENSMUST00000109104.1
avian musculoaponeurotic fibrosarcoma (v-maf) AS42 oncogene homolog
chr17_-_14694223 0.16 ENSMUST00000170872.1
thrombospondin 2
chr5_+_115011111 0.16 ENSMUST00000031530.5
signal peptide peptidase 3
chrX_+_58030622 0.15 ENSMUST00000088627.4
zinc finger protein of the cerebellum 3
chr7_-_18910391 0.15 ENSMUST00000150065.1
ENSMUST00000098780.3
coiled-coil domain containing 61
chr11_+_68691906 0.15 ENSMUST00000102611.3
myosin, heavy polypeptide 10, non-muscle
chr13_-_64153194 0.15 ENSMUST00000059817.4
ENSMUST00000117241.1
zinc finger protein 367
chr6_+_58831456 0.15 ENSMUST00000141600.1
ENSMUST00000122981.1
hect domain and RLD 3
chr2_+_162987502 0.15 ENSMUST00000117123.1
serum/glucocorticoid regulated kinase 2
chr11_+_68692097 0.14 ENSMUST00000018887.8
myosin, heavy polypeptide 10, non-muscle
chr17_-_34603675 0.14 ENSMUST00000015622.7
ring finger protein 5
chr19_-_41981119 0.14 ENSMUST00000026168.2
ENSMUST00000171561.1
MMS19 (MET18 S. cerevisiae)
chr3_-_87263703 0.14 ENSMUST00000146512.1
Fc receptor-like S, scavenger receptor
chr7_+_78914216 0.14 ENSMUST00000120331.2
interferon-stimulated protein
chr18_-_77047282 0.14 ENSMUST00000154665.1
ENSMUST00000026486.6
ENSMUST00000123650.1
ENSMUST00000126153.1
katanin p60 subunit A-like 2
chr9_+_109082485 0.14 ENSMUST00000026735.7
coiled-coil domain containing 51
chr1_+_57774842 0.14 ENSMUST00000167085.1
spermatogenesis associated, serine-rich 2-like
chr2_+_27886416 0.13 ENSMUST00000028280.7
collagen, type V, alpha 1
chr2_-_76982455 0.13 ENSMUST00000011934.5
ENSMUST00000099981.2
ENSMUST00000099980.3
ENSMUST00000111882.2
ENSMUST00000140091.1
titin
chr17_-_35085609 0.13 ENSMUST00000038507.6
lymphocyte antigen 6 complex, locus G6F
chr16_+_21204755 0.13 ENSMUST00000006112.6
Eph receptor B3
chr8_-_4678338 0.13 ENSMUST00000058918.4
predicted gene 7461
chr11_-_100441006 0.13 ENSMUST00000092689.2
5'-nucleotidase, cytosolic IIIB
chr10_-_41809607 0.13 ENSMUST00000019951.9
centrosomal protein 57-like 1
chr2_+_110017879 0.13 ENSMUST00000150183.2
coiled-coil domain containing 34
chr16_-_55895279 0.13 ENSMUST00000099705.3
neurexophilin and PC-esterase domain family, member 3
chr5_+_122206792 0.13 ENSMUST00000145854.1
hydrogen voltage-gated channel 1
chr4_-_129189646 0.13 ENSMUST00000106059.1
S100P binding protein
chr10_-_116549101 0.13 ENSMUST00000164088.1
CCR4-NOT transcription complex, subunit 2
chr8_-_116732991 0.13 ENSMUST00000109102.2
chromodomain protein, Y chromosome-like 2
chr2_-_150485091 0.13 ENSMUST00000109914.1
zinc finger protein 345
chr5_+_137030275 0.12 ENSMUST00000041543.8
VGF nerve growth factor inducible
chr11_+_120232921 0.12 ENSMUST00000122148.1
ENSMUST00000044985.7
BAH domain and coiled-coil containing 1
chr11_-_100441058 0.12 ENSMUST00000107399.2
ENSMUST00000092688.5
5'-nucleotidase, cytosolic IIIB
chr13_+_72628802 0.12 ENSMUST00000074372.4
Iroquois related homeobox 2 (Drosophila)
chr13_+_94173992 0.12 ENSMUST00000121618.1
lipoma HMGIC fusion partner-like 2
chr11_-_106998483 0.12 ENSMUST00000124541.1
karyopherin (importin) alpha 2
chr11_-_84068766 0.12 ENSMUST00000018792.5
dual specificity phosphatase 14
chr2_+_121295437 0.12 ENSMUST00000110639.1
microtubule-associated protein 1 A
chr3_+_96601084 0.12 ENSMUST00000062058.3
Lix1-like
chr9_+_113930934 0.12 ENSMUST00000084885.5
ENSMUST00000009885.7
upstream binding protein 1
chr2_+_110017806 0.12 ENSMUST00000028580.5
coiled-coil domain containing 34
chr11_+_68692070 0.12 ENSMUST00000108673.1
myosin, heavy polypeptide 10, non-muscle
chr18_-_84086379 0.12 ENSMUST00000060303.8
teashirt zinc finger family member 1
chr2_+_146855861 0.12 ENSMUST00000099278.2
ENSMUST00000156232.1
polo-like kinase 1 substrate 1
chr2_-_30474199 0.12 ENSMUST00000065134.2
immediate early response 5-like
chr4_-_151861667 0.11 ENSMUST00000169423.2
calmodulin binding transcription activator 1
chr17_+_31564749 0.11 ENSMUST00000175806.1
ENSMUST00000097352.3
Pbx/knotted 1 homeobox
chr17_-_15564322 0.11 ENSMUST00000147532.1
PR domain containing 9
chr11_-_84068554 0.11 ENSMUST00000164891.1
dual specificity phosphatase 14
chr7_-_113347273 0.11 ENSMUST00000117577.1
BTB (POZ) domain containing 10
chr4_+_28813125 0.11 ENSMUST00000029964.5
ENSMUST00000080934.4
Eph receptor A7
chr17_+_57358682 0.11 ENSMUST00000086763.5
ENSMUST00000004850.7
EGF-like module containing, mucin-like, hormone receptor-like sequence 1
chr5_+_139389785 0.11 ENSMUST00000100514.2
G protein-coupled receptor 146
chr14_-_63509092 0.11 ENSMUST00000022522.8
L-threonine dehydrogenase
chr5_-_138172383 0.11 ENSMUST00000000505.9
minichromosome maintenance deficient 7 (S. cerevisiae)
chr13_-_106936907 0.11 ENSMUST00000080856.7
importin 11
chr5_+_120589020 0.11 ENSMUST00000094391.4
IQ motif containing D
chr13_-_25270076 0.11 ENSMUST00000057866.6
neurensin 1
chrX_+_136270253 0.11 ENSMUST00000178632.1
ENSMUST00000053540.4
nerve growth factor receptor (TNFRSF16) associated protein 1
chr12_-_103338314 0.11 ENSMUST00000149431.1
ankyrin repeat and SOCS box-containing 2
chr11_-_84069179 0.10 ENSMUST00000138208.1
dual specificity phosphatase 14
chr9_+_21337828 0.10 ENSMUST00000034697.7
solute carrier family 44, member 2
chr4_-_151861762 0.10 ENSMUST00000097774.2
calmodulin binding transcription activator 1
chrX_+_136270302 0.10 ENSMUST00000113112.1
nerve growth factor receptor (TNFRSF16) associated protein 1
chr11_-_61453992 0.10 ENSMUST00000060255.7
ENSMUST00000054927.7
ENSMUST00000102661.3
ring finger protein 112
chr14_-_122465677 0.10 ENSMUST00000039118.6
zinc finger protein of the cerebellum 5
chr5_+_120589003 0.10 ENSMUST00000069259.2
IQ motif containing D
chrX_+_136224035 0.10 ENSMUST00000113116.2
transcription elongation factor A (SII)-like 7
chr8_+_71464910 0.10 ENSMUST00000048914.6
mitochondrial ribosomal protein L34
chr2_+_150257517 0.10 ENSMUST00000109922.1
predicted gene 14124
chr5_-_138171813 0.10 ENSMUST00000155902.1
ENSMUST00000148879.1
minichromosome maintenance deficient 7 (S. cerevisiae)
chr18_+_23415400 0.10 ENSMUST00000115832.2
ENSMUST00000047954.7
dystrobrevin alpha
chr7_-_101921186 0.10 ENSMUST00000106965.1
ENSMUST00000106968.1
ENSMUST00000106967.1
leucine rich repeat containing 51
chr11_-_100440928 0.10 ENSMUST00000107397.1
5'-nucleotidase, cytosolic IIIB
chr4_-_151861698 0.10 ENSMUST00000049790.7
calmodulin binding transcription activator 1
chr10_-_40302186 0.09 ENSMUST00000099945.4
S-adenosylmethionine decarboxylase 1
chr11_+_16951371 0.09 ENSMUST00000109635.1
ENSMUST00000061327.1
F-box protein 48
chr9_-_109082372 0.09 ENSMUST00000167504.1
translational machinery associated 7 homolog (S. cerevisiae)
chr14_-_61037937 0.09 ENSMUST00000111236.2
tumor necrosis factor receptor superfamily, member 19
chrX_-_74281707 0.09 ENSMUST00000019232.3
deoxyribonuclease 1-like 1
chr11_-_51606840 0.09 ENSMUST00000074669.3
ENSMUST00000101249.2
ENSMUST00000109103.3
heterogeneous nuclear ribonucleoprotein A/B
chr15_+_23036449 0.09 ENSMUST00000164787.1
cadherin 18
chr2_+_160731684 0.09 ENSMUST00000174885.1
ENSMUST00000109462.1
phospholipase C, gamma 1
chr1_+_57774600 0.09 ENSMUST00000167971.1
ENSMUST00000170139.1
ENSMUST00000171699.1
ENSMUST00000164302.1
spermatogenesis associated, serine-rich 2-like
chr17_+_35841668 0.09 ENSMUST00000174124.1
mediator of DNA damage checkpoint 1
chr17_-_45592485 0.08 ENSMUST00000166119.1
solute carrier family 29 (nucleoside transporters), member 1
chr4_+_98546710 0.08 ENSMUST00000102792.3
InaD-like (Drosophila)
chr2_+_160731258 0.08 ENSMUST00000103115.1
phospholipase C, gamma 1
chr3_+_127633134 0.08 ENSMUST00000029587.7
neurogenin 2
chr6_+_134920401 0.08 ENSMUST00000067327.4
ENSMUST00000003115.6
cyclin-dependent kinase inhibitor 1B
chr6_+_34476207 0.08 ENSMUST00000045372.5
ENSMUST00000138668.1
ENSMUST00000139067.1
2,3-bisphosphoglycerate mutase
chr13_-_71963713 0.08 ENSMUST00000077337.8
Iroquois related homeobox 1 (Drosophila)
chr17_-_45592262 0.08 ENSMUST00000164769.1
solute carrier family 29 (nucleoside transporters), member 1
chr7_-_45434590 0.08 ENSMUST00000107771.3
ENSMUST00000141761.1
RuvB-like protein 2
chr8_-_122611419 0.08 ENSMUST00000015171.9
galactosamine (N-acetyl)-6-sulfate sulfatase
chr10_-_41072279 0.08 ENSMUST00000061796.6
G protein-coupled receptor 6
chr2_-_45117349 0.08 ENSMUST00000176438.2
zinc finger E-box binding homeobox 2
chr4_-_129189512 0.08 ENSMUST00000117965.1
ENSMUST00000106061.2
ENSMUST00000072431.6
S100P binding protein
chr17_-_45592569 0.08 ENSMUST00000163492.1
solute carrier family 29 (nucleoside transporters), member 1
chr7_-_135652273 0.08 ENSMUST00000180693.1
RIKEN cDNA 5830432E09 gene
chr15_-_84105662 0.08 ENSMUST00000082365.5
sulfotransferase family 4A, member 1
chr3_+_96525163 0.08 ENSMUST00000049208.9
hemochromatosis type 2 (juvenile) (human homolog)
chr7_+_78913765 0.07 ENSMUST00000038142.8
interferon-stimulated protein
chr2_-_18048347 0.07 ENSMUST00000066885.5
SKI/DACH domain containing 1
chr7_+_25681158 0.07 ENSMUST00000108403.3
B9 protein domain 2
chr12_-_14152038 0.07 ENSMUST00000020926.6
family with sequence similarity 84, member A
chr4_+_129189760 0.07 ENSMUST00000106054.2
ENSMUST00000001365.2
tyrosyl-tRNA synthetase
chr6_+_127577963 0.07 ENSMUST00000071563.4
EF-hand calcium binding domain 4B
chr4_+_98546919 0.07 ENSMUST00000030290.7
InaD-like (Drosophila)
chr11_+_90249426 0.07 ENSMUST00000107887.1
monocyte to macrophage differentiation-associated
chr7_+_4740137 0.07 ENSMUST00000130215.1
ENSMUST00000108582.3
suppressor of variegation 4-20 homolog 2 (Drosophila)
chr13_+_91461050 0.07 ENSMUST00000004094.8
ENSMUST00000042122.8
single-stranded DNA binding protein 2
chr2_+_162987330 0.07 ENSMUST00000018012.7
serum/glucocorticoid regulated kinase 2
chrX_-_73930751 0.07 ENSMUST00000155597.1
ENSMUST00000114379.1
renin binding protein
chr8_-_46152159 0.07 ENSMUST00000110378.2
sorting nexin 25
chr10_+_81183263 0.07 ENSMUST00000047665.6
death-associated protein kinase 3
chrX_+_101429555 0.07 ENSMUST00000033673.6
non-POU-domain-containing, octamer binding protein
chr4_+_28813152 0.07 ENSMUST00000108194.2
ENSMUST00000108191.1
Eph receptor A7
chr8_-_69625503 0.07 ENSMUST00000121886.1
zinc finger protein 868
chr19_-_14598031 0.07 ENSMUST00000167776.2
transducin-like enhancer of split 4, homolog of Drosophila E(spl)
chr9_+_108692116 0.06 ENSMUST00000035220.6
protein kinase, cAMP dependent regulatory, type II alpha
chr3_+_88579602 0.06 ENSMUST00000035785.7
signal sequence receptor, beta
chr7_+_122289297 0.06 ENSMUST00000064989.5
ENSMUST00000064921.4
protein kinase C, beta
chr4_+_140961203 0.06 ENSMUST00000010007.8
succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
chr16_+_17233560 0.06 ENSMUST00000090190.5
ENSMUST00000115698.2
hypermethylated in cancer 2
chr13_+_114818232 0.06 ENSMUST00000166104.2
ENSMUST00000166176.2
ENSMUST00000184335.1
ENSMUST00000184245.1
ENSMUST00000015680.4
ENSMUST00000184214.1
ENSMUST00000165022.2
ENSMUST00000164737.1
ENSMUST00000184781.1
ENSMUST00000183407.1
ENSMUST00000184672.1
molybdenum cofactor synthesis 2
chr14_-_46831984 0.06 ENSMUST00000181311.1
ENSMUST00000074862.2
predicted gene 10101
chr2_+_173737492 0.06 ENSMUST00000067530.4
vesicle-associated membrane protein, associated protein B and C
chr1_+_32172711 0.06 ENSMUST00000027226.5
KH domain containing, RNA binding, signal transduction associated 2

Network of associatons between targets according to the STRING database.

First level regulatory network of Pbx1_Pbx3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.2 1.0 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.1 0.4 GO:0070650 actin filament bundle distribution(GO:0070650)
0.1 0.4 GO:0072272 proximal/distal pattern formation involved in metanephric nephron development(GO:0072272)
0.1 0.4 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.1 0.2 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.1 0.2 GO:2001205 negative regulation of osteoclast development(GO:2001205)
0.1 0.4 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.1 0.2 GO:2000820 negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000820)
0.1 0.2 GO:2000182 regulation of progesterone biosynthetic process(GO:2000182)
0.1 0.3 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.2 GO:0044268 multicellular organismal protein metabolic process(GO:0044268)
0.0 0.1 GO:0043056 forward locomotion(GO:0043056)
0.0 0.2 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.0 0.2 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.0 0.2 GO:0021631 optic nerve morphogenesis(GO:0021631) smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
0.0 0.1 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.0 0.2 GO:1903758 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.0 0.2 GO:0015862 uridine transport(GO:0015862)
0.0 0.2 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.0 0.4 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.1 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.0 0.2 GO:0048852 diencephalon morphogenesis(GO:0048852)
0.0 0.1 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.0 0.1 GO:0006566 threonine metabolic process(GO:0006566)
0.0 0.1 GO:0071733 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.0 0.2 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.0 0.2 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.0 0.1 GO:0031446 regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448)
0.0 0.1 GO:0060023 soft palate development(GO:0060023)
0.0 0.1 GO:0043519 myosin II filament organization(GO:0031038) regulation of myosin II filament organization(GO:0043519)
0.0 0.2 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.2 GO:2001054 negative regulation of mesenchymal cell apoptotic process(GO:2001054)
0.0 0.2 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.0 GO:0021817 nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration(GO:0021817) nuclear migration along microtubule(GO:0030473)
0.0 0.2 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0 0.2 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.0 0.1 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.0 0.1 GO:0001543 ovarian follicle rupture(GO:0001543)
0.0 0.4 GO:0060539 diaphragm development(GO:0060539)
0.0 0.2 GO:0030007 cellular potassium ion homeostasis(GO:0030007)
0.0 0.2 GO:0036123 histone H3-K9 dimethylation(GO:0036123)
0.0 0.1 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.0 0.2 GO:1901339 regulation of store-operated calcium channel activity(GO:1901339)
0.0 0.1 GO:0097298 regulation of nucleus size(GO:0097298)
0.0 0.3 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.0 0.1 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 0.1 GO:0044830 modulation by host of viral RNA genome replication(GO:0044830)
0.0 0.2 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.2 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.0 0.1 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.5 GO:0032094 response to food(GO:0032094)
0.0 0.0 GO:1902445 regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
0.0 0.1 GO:0071294 cellular response to zinc ion(GO:0071294)
0.0 0.2 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 0.0 GO:2000229 pancreatic stellate cell proliferation(GO:0072343) regulation of pancreatic stellate cell proliferation(GO:2000229)
0.0 0.1 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
0.0 0.2 GO:0021854 hypothalamus development(GO:0021854)
0.0 0.1 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.1 GO:0019720 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.0 0.2 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.1 0.8 GO:0000801 central element(GO:0000801)
0.1 0.4 GO:0031262 Ndc80 complex(GO:0031262)
0.1 0.4 GO:0097513 myosin II filament(GO:0097513)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.3 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.5 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.2 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.2 GO:0071556 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.0 0.3 GO:0072687 meiotic spindle(GO:0072687)
0.0 0.4 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.2 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.1 GO:0097361 CIA complex(GO:0097361)
0.0 0.1 GO:0008623 CHRAC(GO:0008623)
0.0 0.2 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0 0.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.1 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.1 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.0 0.1 GO:1990246 uniplex complex(GO:1990246)
0.0 0.2 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.1 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.1 GO:0045281 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.1 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.2 GO:0042555 MCM complex(GO:0042555)
0.0 0.1 GO:0014802 terminal cisterna(GO:0014802)
0.0 0.2 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.1 GO:0031673 H zone(GO:0031673)
0.0 0.1 GO:0097255 R2TP complex(GO:0097255)
0.0 0.2 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 1.0 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.0 GO:0099522 region of cytosol(GO:0099522) postsynaptic cytosol(GO:0099524)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0031752 D3 dopamine receptor binding(GO:0031750) D5 dopamine receptor binding(GO:0031752)
0.1 0.2 GO:0035939 microsatellite binding(GO:0035939)
0.1 0.4 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.1 0.4 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.1 0.2 GO:0008859 exoribonuclease II activity(GO:0008859)
0.0 0.2 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.3 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.2 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.0 0.3 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.5 GO:0043495 protein anchor(GO:0043495)
0.0 1.5 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.5 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.4 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.1 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.0 0.4 GO:0015197 peptide transporter activity(GO:0015197)
0.0 0.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.2 GO:0008556 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.0 0.1 GO:0019808 polyamine binding(GO:0019808)
0.0 0.4 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.2 GO:0043426 MRF binding(GO:0043426)
0.0 0.1 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177) 3 iron, 4 sulfur cluster binding(GO:0051538)
0.0 0.2 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.1 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.0 0.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.2 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.0 0.1 GO:0001226 RNA polymerase II transcription corepressor binding(GO:0001226)
0.0 0.4 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.0 GO:0031531 thyrotropin-releasing hormone receptor binding(GO:0031531)
0.0 0.2 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.0 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.0 0.1 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0 0.0 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.0 GO:0035650 AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651)
0.0 0.1 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.0 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0 0.3 GO:0005549 odorant binding(GO:0005549)
0.0 0.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553) proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 1.7 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.2 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.4 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.2 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.2 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.5 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 1.0 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.9 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.8 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 1.9 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.4 REACTOME KINESINS Genes involved in Kinesins
0.0 0.1 REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE Genes involved in p53-Dependent G1 DNA Damage Response
0.0 0.4 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.2 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.2 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.2 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling