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12D miR HR13_24

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Results for Cbfb

Z-value: 0.51

Motif logo

Transcription factors associated with Cbfb

Gene Symbol Gene ID Gene Info
ENSMUSG00000031885.7 core binding factor beta

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Cbfbmm10_v2_chr8_+_105170668_105170686-0.521.0e-01Click!

Activity profile of Cbfb motif

Sorted Z-values of Cbfb motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_83649349 0.74 ENSMUST00000001008.5
chemokine (C-C motif) ligand 3
chr14_-_101729690 0.67 ENSMUST00000066461.3
predicted gene 9922
chr1_-_193264006 0.43 ENSMUST00000161737.1
hydroxysteroid 11-beta dehydrogenase 1
chr2_+_164948219 0.37 ENSMUST00000017881.2
matrix metallopeptidase 9
chr7_-_67803489 0.36 ENSMUST00000181235.1
RIKEN cDNA 4833412C05 gene
chr5_+_90518932 0.35 ENSMUST00000113179.2
ENSMUST00000128740.1
afamin
chr2_+_172393794 0.31 ENSMUST00000099061.2
ENSMUST00000103073.2
Cas scaffolding protein family member 4
chr5_+_104435112 0.31 ENSMUST00000031243.8
ENSMUST00000086833.6
ENSMUST00000112748.1
ENSMUST00000112746.1
ENSMUST00000145084.1
ENSMUST00000132457.1
secreted phosphoprotein 1
chr15_-_101370125 0.29 ENSMUST00000077196.4
keratin 80
chr4_+_83417715 0.23 ENSMUST00000030206.3
ENSMUST00000071544.4
small nuclear RNA activating complex, polypeptide 3
chr1_-_174921813 0.21 ENSMUST00000055294.3
gremlin 2 homolog, cysteine knot superfamily (Xenopus laevis)
chr7_-_90129339 0.20 ENSMUST00000181189.1
RIKEN cDNA 2310010J17 gene
chr2_+_172393900 0.18 ENSMUST00000109136.2
Cas scaffolding protein family member 4
chr2_-_58160495 0.18 ENSMUST00000028175.6
cytohesin 1 interacting protein
chr15_+_99392948 0.17 ENSMUST00000161250.1
ENSMUST00000160635.1
ENSMUST00000161778.1
transmembrane BAX inhibitor motif containing 6
chr8_+_84125989 0.17 ENSMUST00000093380.4
podocan-like 1
chr1_+_151755339 0.17 ENSMUST00000059498.5
ER degradation enhancer, mannosidase alpha-like 3
chr15_+_99393219 0.16 ENSMUST00000159209.1
transmembrane BAX inhibitor motif containing 6
chr9_-_48480540 0.15 ENSMUST00000034524.3
REX2, RNA exonuclease 2 homolog (S. cerevisiae)
chr12_+_95692212 0.15 ENSMUST00000057324.3
fibronectin leucine rich transmembrane protein 2
chr6_+_129408854 0.13 ENSMUST00000058352.8
ENSMUST00000164513.2
ENSMUST00000088075.5
C-type lectin domain family 9, member a
chr6_+_126853091 0.12 ENSMUST00000095440.5
A kinase (PRKA) anchor protein 3
chr8_+_27260327 0.12 ENSMUST00000033880.5
eukaryotic translation initiation factor 4E binding protein 1
chr15_+_99393574 0.12 ENSMUST00000162624.1
transmembrane BAX inhibitor motif containing 6
chr11_+_115440540 0.11 ENSMUST00000093914.4
RIKEN cDNA 4933422H20 gene
chr15_+_99393610 0.10 ENSMUST00000159531.1
transmembrane BAX inhibitor motif containing 6
chr16_-_92826004 0.10 ENSMUST00000023673.7
runt related transcription factor 1
chrX_+_99136119 0.10 ENSMUST00000052839.6
ephrin B1
chr9_+_110849507 0.09 ENSMUST00000119427.2
protease, serine, 46
chr17_-_35643684 0.09 ENSMUST00000095467.3
diffuse panbronchiolitis critical region 1 (human)
chr2_+_126034967 0.09 ENSMUST00000110442.1
fibroblast growth factor 7
chr19_+_6061176 0.08 ENSMUST00000162726.3
zinc finger, HIT domain containing 2
chrX_-_101734125 0.08 ENSMUST00000056614.6
chemokine (C-X-C motif) receptor 3
chr14_-_64949838 0.08 ENSMUST00000067843.3
ENSMUST00000176489.1
ENSMUST00000175905.1
ENSMUST00000022544.7
ENSMUST00000175744.1
ENSMUST00000176128.1
homeobox containing 1
chr5_+_24364804 0.07 ENSMUST00000030834.4
ENSMUST00000115090.1
nitric oxide synthase 3, endothelial cell
chr5_-_147400352 0.07 ENSMUST00000049324.8
ENSMUST00000176456.1
ENSMUST00000110549.1
FMS-like tyrosine kinase 3
chr19_+_12798574 0.07 ENSMUST00000025601.6
leupaxin
chr11_-_17008647 0.06 ENSMUST00000102881.3
pleckstrin
chr19_-_50678485 0.06 ENSMUST00000111756.3
VPS10 domain receptor protein SORCS 1
chr9_+_66126611 0.06 ENSMUST00000034945.5
family with sequence similarity 96, member A
chr14_-_67314711 0.05 ENSMUST00000100448.2
predicted gene 6878
chr17_-_64331817 0.05 ENSMUST00000172733.1
ENSMUST00000172818.1
praja 2, RING-H2 motif containing
chr15_-_66801577 0.05 ENSMUST00000168589.1
src-like adaptor
chr2_+_126034647 0.05 ENSMUST00000064794.7
fibroblast growth factor 7
chr9_-_66126559 0.04 ENSMUST00000137542.1
sorting nexin 1
chr3_+_121291725 0.04 ENSMUST00000039442.7
asparagine-linked glycosylation 14
chr11_-_73326472 0.04 ENSMUST00000155630.2
aspartoacylase
chr11_-_51262940 0.04 ENSMUST00000065950.3
cDNA sequence BC049762
chr19_+_5050807 0.03 ENSMUST00000025818.6
Ras and Rab interactor 1
chr11_-_73326807 0.03 ENSMUST00000134079.1
aspartoacylase
chr4_-_117891994 0.02 ENSMUST00000030265.3
DPH2 homolog (S. cerevisiae)
chr15_-_9529868 0.02 ENSMUST00000003981.4
interleukin 7 receptor
chr2_+_153938218 0.02 ENSMUST00000109757.1
BPI fold containing family B, member 4
chr14_+_64950037 0.01 ENSMUST00000043914.5
integrator complex subunit 9
chr1_+_20730903 0.01 ENSMUST00000027061.4
interleukin 17A
chr15_-_101869695 0.00 ENSMUST00000087996.5
keratin 77

Network of associatons between targets according to the STRING database.

First level regulatory network of Cbfb

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0006713 glucocorticoid catabolic process(GO:0006713)
0.1 0.6 GO:1904721 regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.1 0.3 GO:0006710 androgen catabolic process(GO:0006710) estradiol secretion(GO:0035938) regulation of estradiol secretion(GO:2000864)
0.1 0.2 GO:0060300 regulation of cytokine activity(GO:0060300)
0.1 0.7 GO:0043615 astrocyte cell migration(GO:0043615)
0.0 0.4 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.0 0.1 GO:0061033 secretion by lung epithelial cell involved in lung growth(GO:0061033)
0.0 0.1 GO:2000872 positive regulation of progesterone secretion(GO:2000872)
0.0 0.2 GO:0035977 protein deglycosylation involved in glycoprotein catabolic process(GO:0035977) protein demannosylation(GO:0036507) protein alpha-1,2-demannosylation(GO:0036508) glycoprotein ERAD pathway(GO:0097466) mannose trimming involved in glycoprotein ERAD pathway(GO:1904382)
0.0 0.2 GO:0009301 snRNA transcription(GO:0009301)
0.0 0.1 GO:0002572 pro-T cell differentiation(GO:0002572)
0.0 0.1 GO:1990928 response to amino acid starvation(GO:1990928)
0.0 0.1 GO:0014900 regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900)
0.0 0.1 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.0 0.1 GO:0010920 negative regulation of inositol phosphate biosynthetic process(GO:0010920) protein secretion by platelet(GO:0070560)
0.0 0.1 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.0 0.1 GO:0006083 acetate metabolic process(GO:0006083)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 GO:0030905 retromer, tubulation complex(GO:0030905)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.1 0.3 GO:0008431 vitamin E binding(GO:0008431)
0.1 0.6 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.0 0.1 GO:0034617 nitric-oxide synthase activity(GO:0004517) tetrahydrobiopterin binding(GO:0034617)
0.0 0.1 GO:0019807 aspartoacylase activity(GO:0019807)
0.0 0.7 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.1 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.0 0.2 GO:0036122 BMP binding(GO:0036122)
0.0 0.2 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.1 GO:0019958 C-X-C chemokine binding(GO:0019958)
0.0 0.0 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.1 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.4 GO:0001968 fibronectin binding(GO:0001968)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 PID AVB3 OPN PATHWAY Osteopontin-mediated events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.4 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.2 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.4 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix