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12D miR HR13_24

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Results for Epas1_Bcl3

Z-value: 1.46

Motif logo

Transcription factors associated with Epas1_Bcl3

Gene Symbol Gene ID Gene Info
ENSMUSG00000024140.9 endothelial PAS domain protein 1
ENSMUSG00000053175.10 B cell leukemia/lymphoma 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Epas1mm10_v2_chr17_+_86753900_86753914-0.784.8e-03Click!
Bcl3mm10_v2_chr7_-_19822698_198227760.058.9e-01Click!

Activity profile of Epas1_Bcl3 motif

Sorted Z-values of Epas1_Bcl3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_3357012 4.49 ENSMUST00000180719.1
predicted gene, 26520
chr1_-_158958367 3.46 ENSMUST00000159861.2
pappalysin 2
chr13_+_89540636 2.80 ENSMUST00000022108.7
hyaluronan and proteoglycan link protein 1
chr11_+_34314757 2.73 ENSMUST00000165963.1
ENSMUST00000093192.3
family with sequence similarity 196, member B
chr2_+_169632996 2.69 ENSMUST00000109159.2
teashirt zinc finger family member 2
chrX_-_38252398 2.53 ENSMUST00000089056.3
ENSMUST00000089054.4
ENSMUST00000066498.7
transmembrane protein 255A
chr3_-_97297778 2.41 ENSMUST00000181368.1
predicted gene, 17608
chr6_-_129233969 2.38 ENSMUST00000181517.1
RIKEN cDNA 2310001H17 gene
chr19_+_16956110 2.27 ENSMUST00000087689.4
prune homolog 2 (Drosophila)
chr1_-_174921813 2.03 ENSMUST00000055294.3
gremlin 2 homolog, cysteine knot superfamily (Xenopus laevis)
chr8_+_82863351 1.98 ENSMUST00000078525.5
ring finger protein 150
chr2_+_174760619 1.77 ENSMUST00000029030.2
endothelin 3
chr5_+_102481546 1.67 ENSMUST00000112854.1
Rho GTPase activating protein 24
chrX_+_164506320 1.63 ENSMUST00000033756.2
ankyrin repeat and SOCS box-containing 9
chr6_-_129385497 1.58 ENSMUST00000032261.6
C-type lectin domain family 12, member B
chr2_+_135659625 1.47 ENSMUST00000134310.1
phospholipase C, beta 4
chr13_-_92131494 1.46 ENSMUST00000099326.3
ENSMUST00000146492.1
RAS protein-specific guanine nucleotide-releasing factor 2
chr5_-_30461902 1.45 ENSMUST00000133509.1
ENSMUST00000074171.6
ENSMUST00000114747.2
ENSMUST00000144125.1
otoferlin
chr1_+_75507077 1.36 ENSMUST00000037330.4
inhibin alpha
chr11_+_61022560 1.36 ENSMUST00000089184.4
potassium inwardly-rectifying channel, subfamily J, member 12
chr6_-_112946754 1.35 ENSMUST00000113169.2
SLIT-ROBO Rho GTPase activating protein 3
chr2_+_105127200 1.34 ENSMUST00000139585.1
Wilms tumor 1 homolog
chrX_-_162159717 1.30 ENSMUST00000087085.3
Nance-Horan syndrome (human)
chr19_+_8664005 1.29 ENSMUST00000035444.3
ENSMUST00000163785.1
cholinergic receptor, muscarinic 1, CNS
chr7_-_100863373 1.25 ENSMUST00000142885.1
ENSMUST00000008462.3
RELT tumor necrosis factor receptor
chr11_+_71750680 1.21 ENSMUST00000021168.7
WSC domain containing 1
chr2_+_106695594 1.19 ENSMUST00000016530.7
metallophosphoesterase domain containing 2
chr1_+_109982710 1.17 ENSMUST00000112701.1
cadherin 7, type 2
chr6_+_47244359 1.17 ENSMUST00000060839.6
contactin associated protein-like 2
chr7_-_141117772 1.16 ENSMUST00000067836.7
anoctamin 9
chr4_-_132144486 1.16 ENSMUST00000056336.1
opioid receptor, delta 1
chr19_+_23758819 1.12 ENSMUST00000025830.7
amyloid beta (A4) precursor protein binding, family A, member 1
chr15_-_68363139 1.10 ENSMUST00000175699.1
predicted gene 20732
chr5_+_35757875 1.09 ENSMUST00000101280.3
ENSMUST00000054598.5
ENSMUST00000114205.1
ENSMUST00000114206.2
actin-binding LIM protein 2
chr6_-_112947246 1.06 ENSMUST00000088373.4
SLIT-ROBO Rho GTPase activating protein 3
chr7_-_100656953 1.01 ENSMUST00000107046.1
ENSMUST00000107045.1
ENSMUST00000139708.1
pleckstrin homology domain containing, family B (evectins) member 1
chr6_-_124768330 1.00 ENSMUST00000135626.1
enolase 2, gamma neuronal
chr3_+_105452326 0.97 ENSMUST00000098761.3
potassium voltage-gated channel, Shal-related family, member 3
chr16_-_52454074 0.96 ENSMUST00000023312.7
activated leukocyte cell adhesion molecule
chr3_-_152668135 0.94 ENSMUST00000045262.6
adenylate kinase 5
chr4_-_134018829 0.93 ENSMUST00000051674.2
lin-28 homolog A (C. elegans)
chr4_-_42661893 0.92 ENSMUST00000108006.3
interleukin 11 receptor, alpha chain 2
chr17_-_28560704 0.90 ENSMUST00000114785.1
ENSMUST00000025062.3
colipase, pancreatic
chr2_-_63184253 0.90 ENSMUST00000075052.3
ENSMUST00000112454.1
potassium voltage-gated channel, subfamily H (eag-related), member 7
chr5_+_64970069 0.90 ENSMUST00000031080.8
family with sequence similarity 114, member A1
chr2_+_119351222 0.89 ENSMUST00000028780.3
ChaC, cation transport regulator 1
chr1_+_195017399 0.89 ENSMUST00000181273.1
RIKEN cDNA A330023F24 gene
chr10_-_5550636 0.88 ENSMUST00000041639.5
spectrin repeat containing, nuclear envelope 1
chr4_-_20778527 0.88 ENSMUST00000119374.1
Na+/K+ transporting ATPase interacting 3
chrX_+_142681398 0.87 ENSMUST00000112889.1
ENSMUST00000101198.2
ENSMUST00000112891.1
ENSMUST00000087333.2
transmembrane protein 164
chr7_+_121392266 0.87 ENSMUST00000084628.3
heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr15_-_3583146 0.86 ENSMUST00000110698.2
growth hormone receptor
chr15_+_57694651 0.84 ENSMUST00000096430.4
zinc fingers and homeoboxes 2
chr1_-_90969644 0.83 ENSMUST00000130042.1
ENSMUST00000027529.5
RAB17, member RAS oncogene family
chrX_+_140664908 0.81 ENSMUST00000112990.1
ENSMUST00000112988.1
midline 2
chr11_+_95010277 0.81 ENSMUST00000124735.1
sterile alpha motif domain containing 14
chr11_-_69695521 0.79 ENSMUST00000181261.1
tumor necrosis factor (ligand) superfamily, member 12
chr12_-_86892540 0.74 ENSMUST00000181290.1
predicted gene, 26698
chrX_+_140664565 0.74 ENSMUST00000128809.1
midline 2
chr4_+_49059256 0.73 ENSMUST00000076670.2
RIKEN cDNA E130309F12 gene
chr12_-_67221221 0.73 ENSMUST00000178814.1
ENSMUST00000179345.2
MAM domain containing glycosylphosphatidylinositol anchor 2
MAM domain-containing glycosylphosphatidylinositol anchor protein 2
chr17_-_29237759 0.71 ENSMUST00000137727.1
ENSMUST00000024805.7
copine V
chr4_-_126325641 0.70 ENSMUST00000131113.1
tektin 2
chr18_+_49979427 0.70 ENSMUST00000148989.2
tumor necrosis factor, alpha-induced protein 8
chr17_+_48932368 0.70 ENSMUST00000046254.2
leucine rich repeat and fibronectin type III domain containing 2
chr3_+_51661167 0.70 ENSMUST00000099106.3
microsomal glutathione S-transferase 2
chr18_+_49979514 0.70 ENSMUST00000179937.1
tumor necrosis factor, alpha-induced protein 8
chr4_+_137862237 0.69 ENSMUST00000102518.3
endothelin converting enzyme 1
chr8_+_62951361 0.68 ENSMUST00000119068.1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan 3
chr11_+_114851814 0.67 ENSMUST00000053361.5
ENSMUST00000021071.7
ENSMUST00000136785.1
G protein-coupled receptor, family C, group 5, member C
chr11_-_101785252 0.65 ENSMUST00000164750.1
ENSMUST00000107176.1
ENSMUST00000017868.6
ets variant gene 4 (E1A enhancer binding protein, E1AF)
chr13_+_58807884 0.64 ENSMUST00000079828.5
neurotrophic tyrosine kinase, receptor, type 2
chr6_+_71199827 0.64 ENSMUST00000067492.7
fatty acid binding protein 1, liver
chr8_-_3694167 0.63 ENSMUST00000005678.4
Fc receptor, IgE, low affinity II, alpha polypeptide
chr10_+_17796256 0.63 ENSMUST00000037964.6
taxilin beta
chr2_+_4300462 0.63 ENSMUST00000175669.1
FERM domain containing 4A
chr4_+_32983417 0.63 ENSMUST00000084747.5
Ras-related GTP binding D
chr6_+_40628824 0.62 ENSMUST00000071535.6
maltase-glucoamylase
chr5_+_81021583 0.62 ENSMUST00000121707.1
latrophilin 3
chr11_-_105944128 0.62 ENSMUST00000184086.1
cytochrome b-561
chr11_-_105944412 0.60 ENSMUST00000019734.4
ENSMUST00000184269.1
ENSMUST00000150563.1
cytochrome b-561
chr17_-_34882094 0.60 ENSMUST00000025230.8
complement component 2 (within H-2S)
chr4_-_126325672 0.59 ENSMUST00000102616.1
tektin 2
chr2_+_105126505 0.59 ENSMUST00000143043.1
Wilms tumor 1 homolog
chr8_+_68880491 0.58 ENSMUST00000015712.8
lipoprotein lipase
chrX_-_64276937 0.58 ENSMUST00000114679.1
ENSMUST00000069926.7
SLIT and NTRK-like family, member 4
chr14_-_60177482 0.58 ENSMUST00000140924.1
ATPase, aminophospholipid transporter-like, class I, type 8A, member 2
chr6_+_124493101 0.57 ENSMUST00000049124.9
complement component 1, r subcomponent-like
chr16_-_59553970 0.57 ENSMUST00000139989.1
beta-gamma crystallin domain containing 3
chr18_-_80713062 0.57 ENSMUST00000170905.1
ENSMUST00000078049.4
nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1
chr15_-_3583191 0.56 ENSMUST00000069451.4
growth hormone receptor
chr11_+_3983636 0.56 ENSMUST00000078757.1
galactose-3-O-sulfotransferase 1
chr5_-_92505518 0.56 ENSMUST00000031377.7
scavenger receptor class B, member 2
chr8_-_33731793 0.56 ENSMUST00000079376.5
RIKEN cDNA 1700104B16 gene
chr17_-_57078490 0.55 ENSMUST00000011623.7
DENN/MADD domain containing 1C
chr3_+_134236483 0.55 ENSMUST00000181904.1
ENSMUST00000053048.9
CXXC finger 4
chr8_+_23153271 0.55 ENSMUST00000071588.6
NK6 homeobox 3
chr6_-_29179584 0.54 ENSMUST00000159200.1
proline-rich transmembrane protein 4
chr7_+_100607410 0.54 ENSMUST00000107048.1
ENSMUST00000032946.3
RAB6A, member RAS oncogene family
chr4_-_97778042 0.53 ENSMUST00000146447.1
RIKEN cDNA E130114P18 gene
chr17_-_34882004 0.52 ENSMUST00000152417.1
ENSMUST00000146299.1
complement component 2 (within H-2S)
predicted gene 20547
chr5_+_81021202 0.52 ENSMUST00000117253.1
ENSMUST00000120128.1
latrophilin 3
chr9_+_89909775 0.50 ENSMUST00000034912.4
ENSMUST00000034909.4
RAS protein-specific guanine nucleotide-releasing factor 1
chr5_-_92083667 0.50 ENSMUST00000113127.3
GTPase activating protein (SH3 domain) binding protein 2
chrX_+_7842056 0.50 ENSMUST00000115667.3
ENSMUST00000115668.3
ENSMUST00000115665.1
OTU domain containing 5
chr5_-_92083455 0.50 ENSMUST00000169094.1
ENSMUST00000167918.1
GTPase activating protein (SH3 domain) binding protein 2
chr1_+_120340569 0.50 ENSMUST00000037286.8
complement component 1, q subcomponent-like 2
chr2_-_113217051 0.50 ENSMUST00000080673.5
ryanodine receptor 3
chr5_-_123141067 0.49 ENSMUST00000162697.1
ENSMUST00000160321.1
ENSMUST00000159637.1
expressed sequence AI480526
chr7_+_100607660 0.49 ENSMUST00000098252.4
RAB6A, member RAS oncogene family
chr9_-_75409951 0.49 ENSMUST00000049355.10
mitogen-activated protein kinase 6
chr3_+_154664096 0.48 ENSMUST00000172865.1
RIKEN cDNA 4922501L14 gene
chr4_+_32983008 0.48 ENSMUST00000098190.3
ENSMUST00000029946.7
Ras-related GTP binding D
chr7_-_141539784 0.47 ENSMUST00000118694.1
ENSMUST00000153191.1
ENSMUST00000166082.1
ENSMUST00000026586.6
chitinase domain containing 1
chr11_+_114851507 0.47 ENSMUST00000177952.1
G protein-coupled receptor, family C, group 5, member C
chr12_-_16800674 0.47 ENSMUST00000162112.1
gene regulated by estrogen in breast cancer protein
chr19_+_55898553 0.46 ENSMUST00000148666.1
transcription factor 7 like 2, T cell specific, HMG box
chrX_+_69360294 0.45 ENSMUST00000033532.6
AF4/FMR2 family, member 2
chr14_+_118137101 0.45 ENSMUST00000022728.2
G protein-coupled receptor 180
chr11_+_71749914 0.44 ENSMUST00000150531.1
WSC domain containing 1
chr9_+_103008479 0.44 ENSMUST00000035148.6
solute carrier organic anion transporter family, member 2a1
chr9_-_121759788 0.44 ENSMUST00000181325.1
RIKEN cDNA E530011L22 gene
chr5_+_135168382 0.44 ENSMUST00000111187.3
ENSMUST00000111188.1
B cell CLL/lymphoma 7B
chrX_+_53607987 0.42 ENSMUST00000063384.3
ENSMUST00000169626.1
CAAX box 1C
chr14_-_70630149 0.42 ENSMUST00000022694.9
dematin actin binding protein
chr4_-_20778852 0.42 ENSMUST00000102998.3
Na+/K+ transporting ATPase interacting 3
chrX_+_23693043 0.42 ENSMUST00000035766.6
ENSMUST00000101670.2
WD repeat domain 44
chrX_+_144688907 0.41 ENSMUST00000112843.1
zinc finger, CCHC domain containing 16
chr5_+_135168283 0.41 ENSMUST00000031692.5
B cell CLL/lymphoma 7B
chr14_-_54994541 0.41 ENSMUST00000153783.1
ENSMUST00000168485.1
ENSMUST00000102803.3
myosin, heavy polypeptide 7, cardiac muscle, beta
chr7_+_99535439 0.41 ENSMUST00000098266.2
ENSMUST00000179755.1
arrestin, beta 1
chr6_+_91684061 0.40 ENSMUST00000032185.7
solute carrier family 6 (neurotransmitter transporter, taurine), member 6
chr7_+_99535652 0.40 ENSMUST00000032995.8
ENSMUST00000162404.1
arrestin, beta 1
chr1_+_166254095 0.39 ENSMUST00000111416.1
immunoglobulin-like domain containing receptor 2
chr7_+_31059342 0.39 ENSMUST00000039775.7
leucine-rich repeat LGI family, member 4
chr2_-_52676571 0.38 ENSMUST00000178799.1
calcium channel, voltage-dependent, beta 4 subunit
chr6_-_84593810 0.38 ENSMUST00000077705.3
ENSMUST00000168003.2
cytochrome P450, family 26, subfamily b, polypeptide 1
chr10_+_102512216 0.38 ENSMUST00000055355.4
Ras association (RalGDS/AF-6) domain family (N-terminal) member 9
chr12_+_4234023 0.38 ENSMUST00000179139.1
peptidyl-tRNA hydrolase domain containing 1
chr5_-_74677792 0.38 ENSMUST00000117525.1
ENSMUST00000153543.1
ENSMUST00000039744.6
ENSMUST00000113531.2
ENSMUST00000121690.1
ligand of numb-protein X 1
chr11_+_100859351 0.37 ENSMUST00000004145.7
ENSMUST00000133036.1
signal transducer and activator of transcription 5A
chr10_+_81628540 0.36 ENSMUST00000123896.1
ankyrin repeat domain 24
chr3_-_30509752 0.36 ENSMUST00000172697.1
MDS1 and EVI1 complex locus
chr15_+_59315030 0.36 ENSMUST00000022977.7
squalene epoxidase
chr2_+_153345809 0.36 ENSMUST00000109790.1
additional sex combs like 1
chr15_+_59315088 0.36 ENSMUST00000100640.4
squalene epoxidase
chr2_+_119237531 0.36 ENSMUST00000110817.2
serine protease inhibitor, Kunitz type 1
chr11_+_95009852 0.35 ENSMUST00000055947.3
sterile alpha motif domain containing 14
chr2_+_71786923 0.35 ENSMUST00000112101.1
ENSMUST00000028522.3
integrin alpha 6
chr18_+_76059458 0.35 ENSMUST00000167921.1
zinc finger and BTB domain containing 7C
chr1_+_87470258 0.35 ENSMUST00000027476.4
RIKEN cDNA 3110079O15 gene
chrX_+_53607918 0.35 ENSMUST00000114827.1
CAAX box 1C
chr6_-_72788952 0.34 ENSMUST00000114053.2
transcription factor 7 like 1 (T cell specific, HMG box)
chr12_-_4233958 0.34 ENSMUST00000111169.3
ENSMUST00000020981.5
centromere protein O
chr15_-_89477400 0.34 ENSMUST00000165199.1
arylsulfatase A
chr19_+_6400611 0.34 ENSMUST00000113467.1
RAS, guanyl releasing protein 2
chr14_+_55765956 0.34 ENSMUST00000057569.3
leukotriene B4 receptor 1
chr2_-_172940299 0.34 ENSMUST00000009143.7
bone morphogenetic protein 7
chr2_+_119237351 0.34 ENSMUST00000028783.7
serine protease inhibitor, Kunitz type 1
chr11_+_100859492 0.34 ENSMUST00000107356.1
signal transducer and activator of transcription 5A
chr2_+_119237453 0.33 ENSMUST00000110816.1
serine protease inhibitor, Kunitz type 1
chr11_+_97799565 0.33 ENSMUST00000043843.5
LIM and SH3 protein 1
chr3_+_105904377 0.33 ENSMUST00000000574.1
adenosine A3 receptor
chr9_+_75410145 0.33 ENSMUST00000180533.1
ENSMUST00000180574.1
RIKEN cDNA 4933433G15 gene
chr18_-_38866702 0.33 ENSMUST00000115582.1
fibroblast growth factor 1
chr2_+_28840406 0.33 ENSMUST00000113853.2
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 31
chr2_-_63184170 0.32 ENSMUST00000112452.1
potassium voltage-gated channel, subfamily H (eag-related), member 7
chr8_-_106136792 0.32 ENSMUST00000146940.1
epithelial splicing regulatory protein 2
chr1_-_9299238 0.32 ENSMUST00000140295.1
syntrophin, gamma 1
chr4_-_129239165 0.32 ENSMUST00000097873.3
expressed sequence C77080
chr15_+_39745926 0.31 ENSMUST00000022913.4
dentrocyte expressed seven transmembrane protein
chr8_-_106136890 0.31 ENSMUST00000115979.2
epithelial splicing regulatory protein 2
chr13_+_55369732 0.31 ENSMUST00000063771.7
regulator of G-protein signaling 14
chr5_-_123140135 0.31 ENSMUST00000160099.1
expressed sequence AI480526
chr4_-_126968124 0.31 ENSMUST00000106108.2
zinc finger, MYM-type 4
chr16_+_64851991 0.31 ENSMUST00000067744.7
CGG triplet repeat binding protein 1
chr1_+_152399824 0.31 ENSMUST00000044311.8
collagen beta(1-O)galactosyltransferase 2
chr13_+_31558157 0.31 ENSMUST00000042118.8
forkhead box Q1
chr5_+_146231211 0.30 ENSMUST00000161181.1
ENSMUST00000161652.1
ENSMUST00000031640.8
ENSMUST00000159467.1
cyclin-dependent kinase 8
chr6_+_88724462 0.30 ENSMUST00000113582.1
monoglyceride lipase
chr9_+_48495345 0.30 ENSMUST00000048824.7
predicted gene 5617
chr1_+_59912972 0.30 ENSMUST00000036540.5
family with sequence similarity 117, member B
chr6_-_128826305 0.29 ENSMUST00000174544.1
ENSMUST00000172887.1
ENSMUST00000032472.4
killer cell lectin-like receptor subfamily B member 1B
chr4_+_117096049 0.29 ENSMUST00000030443.5
patched homolog 2
chr13_-_94358818 0.29 ENSMUST00000059598.2
predicted gene 9776
chr9_-_75409352 0.29 ENSMUST00000168937.1
mitogen-activated protein kinase 6
chr15_+_81936911 0.29 ENSMUST00000135663.1
cold shock domain containing C2, RNA binding
chr8_+_85083269 0.29 ENSMUST00000034121.9
mannosidase 2, alpha B1
chr10_+_127642975 0.28 ENSMUST00000092074.5
ENSMUST00000120279.1
signal transducer and activator of transcription 6
chr6_+_65671590 0.28 ENSMUST00000054351.4
neuron-derived neurotrophic factor
chr17_+_78508063 0.28 ENSMUST00000024880.9
vitrin
chr7_+_43634718 0.28 ENSMUST00000032663.8
carcinoembryonic antigen-related cell adhesion molecule 18
chr12_+_61523889 0.27 ENSMUST00000119481.1
ENSMUST00000055815.7
leucine rich repeat and fibronectin type III domain containing 5
chr10_-_127751707 0.27 ENSMUST00000079692.5
G protein-coupled receptor 182
chr12_+_17690793 0.27 ENSMUST00000071858.3
hippocalcin-like 1
chr9_-_87731248 0.27 ENSMUST00000034991.7
T-box18
chr6_-_142964404 0.27 ENSMUST00000032421.3
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
chr6_+_88724828 0.27 ENSMUST00000089449.2
monoglyceride lipase
chr10_-_117845935 0.27 ENSMUST00000064667.7
RAS related protein 1b
chr7_+_144896523 0.26 ENSMUST00000033389.5
fibroblast growth factor 15

Network of associatons between targets according to the STRING database.

First level regulatory network of Epas1_Bcl3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0060300 regulation of cytokine activity(GO:0060300)
0.6 1.9 GO:0072299 negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302) regulation of metanephric ureteric bud development(GO:2001074) positive regulation of metanephric ureteric bud development(GO:2001076)
0.4 1.6 GO:0002767 immune response-inhibiting cell surface receptor signaling pathway(GO:0002767)
0.4 1.2 GO:2001226 negative regulation of chloride transport(GO:2001226)
0.3 1.5 GO:0007207 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.3 1.8 GO:0003100 regulation of systemic arterial blood pressure by endothelin(GO:0003100) vein smooth muscle contraction(GO:0014826)
0.3 1.4 GO:0046882 negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.3 1.3 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.3 2.5 GO:0000255 allantoin metabolic process(GO:0000255) creatinine metabolic process(GO:0046449)
0.2 0.7 GO:0010816 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.2 0.8 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.2 1.0 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.2 1.2 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.2 0.6 GO:0060854 patterning of lymph vessels(GO:0060854)
0.2 1.7 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.2 0.2 GO:1901074 regulation of engulfment of apoptotic cell(GO:1901074)
0.2 0.8 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.2 1.6 GO:0035372 protein localization to microtubule(GO:0035372)
0.1 0.9 GO:0043578 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1 0.6 GO:1905077 negative regulation of interleukin-17 secretion(GO:1905077)
0.1 0.4 GO:0035585 calcium-mediated signaling using extracellular calcium source(GO:0035585)
0.1 1.1 GO:0071233 response to leucine(GO:0043201) cellular response to leucine(GO:0071233)
0.1 0.3 GO:0072198 mesenchymal cell proliferation involved in ureter development(GO:0072198) regulation of mesenchymal cell proliferation involved in ureter development(GO:0072199)
0.1 0.4 GO:0045796 negative regulation of intestinal phytosterol absorption(GO:0010949) negative regulation of intestinal cholesterol absorption(GO:0045796) intestinal phytosterol absorption(GO:0060752) negative regulation of intestinal lipid absorption(GO:1904730)
0.1 0.4 GO:1902809 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653) cornification(GO:0070268) regulation of skeletal muscle fiber differentiation(GO:1902809)
0.1 1.1 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.1 0.5 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.1 0.2 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.1 0.3 GO:0046021 regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.1 0.3 GO:0072125 negative regulation of glomerular mesangial cell proliferation(GO:0072125) negative regulation of glomerulus development(GO:0090194)
0.1 0.9 GO:0010587 miRNA catabolic process(GO:0010587)
0.1 0.4 GO:0014724 regulation of twitch skeletal muscle contraction(GO:0014724)
0.1 0.7 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.1 1.0 GO:0097623 potassium ion export across plasma membrane(GO:0097623)
0.1 0.3 GO:0035771 interleukin-4-mediated signaling pathway(GO:0035771) positive regulation of isotype switching to IgE isotypes(GO:0048295)
0.1 0.7 GO:0033600 negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.1 0.4 GO:0035521 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.1 0.5 GO:0035063 nuclear speck organization(GO:0035063)
0.1 1.5 GO:0015812 gamma-aminobutyric acid secretion(GO:0014051) gamma-aminobutyric acid transport(GO:0015812)
0.1 0.4 GO:0034436 glycoprotein transport(GO:0034436)
0.1 1.0 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1 1.3 GO:0036159 inner dynein arm assembly(GO:0036159)
0.1 0.3 GO:1901079 positive regulation of relaxation of muscle(GO:1901079)
0.1 0.2 GO:1903972 regulation of macrophage colony-stimulating factor signaling pathway(GO:1902226) regulation of response to macrophage colony-stimulating factor(GO:1903969) regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903972)
0.1 0.6 GO:0099550 trans-synaptic signalling, modulating synaptic transmission(GO:0099550)
0.1 0.3 GO:0034241 positive regulation of macrophage fusion(GO:0034241)
0.1 0.9 GO:0006751 glutathione catabolic process(GO:0006751)
0.1 0.3 GO:0006788 heme oxidation(GO:0006788)
0.1 0.6 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.1 0.2 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.1 0.2 GO:0002266 follicular dendritic cell activation(GO:0002266) follicular dendritic cell differentiation(GO:0002268)
0.1 0.6 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.1 0.3 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.1 0.2 GO:0002270 plasmacytoid dendritic cell activation(GO:0002270) negative regulation of apoptotic cell clearance(GO:2000426)
0.1 2.0 GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.1 0.6 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.1 0.2 GO:0003218 cardiac left ventricle formation(GO:0003218)
0.1 1.5 GO:0016082 synaptic vesicle priming(GO:0016082)
0.1 0.2 GO:0097195 pilomotor reflex(GO:0097195) positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.1 0.2 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582)
0.1 0.2 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.1 0.2 GO:0030070 insulin processing(GO:0030070)
0.1 1.0 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.1 0.7 GO:0019370 glutathione biosynthetic process(GO:0006750) leukotriene biosynthetic process(GO:0019370)
0.1 0.3 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.1 0.3 GO:0061056 sclerotome development(GO:0061056)
0.1 0.5 GO:0044334 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) embryonic hindgut morphogenesis(GO:0048619)
0.0 0.6 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 0.3 GO:0002441 histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
0.0 0.2 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897) regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.0 0.3 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.2 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0 0.2 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.0 0.1 GO:0015855 nucleobase transport(GO:0015851) pyrimidine nucleobase transport(GO:0015855)
0.0 0.1 GO:0006713 glucocorticoid catabolic process(GO:0006713)
0.0 0.2 GO:0044830 modulation by host of viral RNA genome replication(GO:0044830)
0.0 0.1 GO:2000182 regulation of progesterone biosynthetic process(GO:2000182)
0.0 0.2 GO:1903278 regulation of sodium ion export(GO:1903273) positive regulation of sodium ion export(GO:1903275) regulation of sodium ion export from cell(GO:1903276) positive regulation of sodium ion export from cell(GO:1903278)
0.0 0.4 GO:0035878 nail development(GO:0035878)
0.0 1.0 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.6 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.0 0.2 GO:0097167 circadian regulation of translation(GO:0097167)
0.0 0.1 GO:0018199 peptidyl-glutamine modification(GO:0018199)
0.0 0.7 GO:0051481 negative regulation of cytosolic calcium ion concentration(GO:0051481)
0.0 1.5 GO:0043267 negative regulation of potassium ion transport(GO:0043267)
0.0 0.5 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.0 0.7 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 0.8 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.0 0.2 GO:0033058 directional locomotion(GO:0033058)
0.0 0.7 GO:0015732 prostaglandin transport(GO:0015732)
0.0 0.3 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.5 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.0 0.1 GO:0060912 cardiac cell fate specification(GO:0060912)
0.0 0.4 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.0 0.1 GO:0071879 response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016) positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.0 0.2 GO:1904252 negative regulation of bile acid biosynthetic process(GO:0070858) negative regulation of bile acid metabolic process(GO:1904252)
0.0 0.1 GO:0001802 antibody-dependent cellular cytotoxicity(GO:0001788) type III hypersensitivity(GO:0001802) regulation of type III hypersensitivity(GO:0001803) positive regulation of type III hypersensitivity(GO:0001805)
0.0 0.2 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.4 GO:0019236 response to pheromone(GO:0019236)
0.0 0.9 GO:0032094 response to food(GO:0032094)
0.0 0.2 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371) regulation of SA node cell action potential(GO:0098907)
0.0 0.2 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.1 GO:0015722 canalicular bile acid transport(GO:0015722)
0.0 0.2 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.0 0.2 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.2 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.2 GO:0048859 formation of anatomical boundary(GO:0048859)
0.0 1.4 GO:0032611 interleukin-1 beta production(GO:0032611)
0.0 0.3 GO:0002295 T-helper cell lineage commitment(GO:0002295)
0.0 0.1 GO:1903225 tendon development(GO:0035989) negative regulation of endodermal cell differentiation(GO:1903225)
0.0 0.3 GO:0090209 negative regulation of triglyceride metabolic process(GO:0090209)
0.0 0.1 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.0 0.1 GO:0035262 gonad morphogenesis(GO:0035262)
0.0 0.5 GO:0010107 potassium ion import(GO:0010107)
0.0 0.1 GO:0032264 IMP salvage(GO:0032264)
0.0 0.6 GO:0060445 branching involved in salivary gland morphogenesis(GO:0060445)
0.0 0.3 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.1 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.0 0.1 GO:0031629 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.0 0.1 GO:2001015 negative regulation of skeletal muscle cell differentiation(GO:2001015)
0.0 1.1 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.2 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 1.9 GO:0006165 nucleoside diphosphate phosphorylation(GO:0006165)
0.0 0.0 GO:0048239 negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695)
0.0 0.1 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.0 1.3 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.0 1.2 GO:0022900 electron transport chain(GO:0022900)
0.0 0.1 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.0 0.1 GO:0043585 nose morphogenesis(GO:0043585) alveolar primary septum development(GO:0061143)
0.0 0.3 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 0.3 GO:0022011 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0 0.3 GO:0045953 negative regulation of natural killer cell mediated cytotoxicity(GO:0045953)
0.0 0.1 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
0.0 0.4 GO:0048266 behavioral response to pain(GO:0048266)
0.0 0.4 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.4 GO:0001893 maternal placenta development(GO:0001893)
0.0 0.2 GO:0031069 hair follicle morphogenesis(GO:0031069)
0.0 0.3 GO:0034508 centromere complex assembly(GO:0034508)
0.0 0.4 GO:0006958 complement activation, classical pathway(GO:0006958)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0070195 growth hormone receptor complex(GO:0070195)
0.5 1.4 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.3 1.0 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.2 1.1 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 0.4 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.1 1.5 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.1 0.2 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.1 0.6 GO:0043202 lysosomal lumen(GO:0043202)
0.1 1.0 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 0.4 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.1 0.9 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 0.2 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.1 0.7 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 1.3 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 0.2 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.1 0.5 GO:0030314 junctional membrane complex(GO:0030314)
0.1 0.5 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 0.6 GO:0045179 apical cortex(GO:0045179)
0.0 1.0 GO:0034385 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.0 0.8 GO:0031143 pseudopodium(GO:0031143)
0.0 0.1 GO:0046691 intracellular canaliculus(GO:0046691)
0.0 0.8 GO:0032156 septin cytoskeleton(GO:0032156)
0.0 0.7 GO:0032279 asymmetric synapse(GO:0032279)
0.0 0.3 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.2 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.0 1.0 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.1 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.0 0.2 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.7 GO:0043196 varicosity(GO:0043196)
0.0 0.2 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.0 1.0 GO:0042101 T cell receptor complex(GO:0042101)
0.0 1.2 GO:0032590 dendrite membrane(GO:0032590)
0.0 0.3 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.8 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.4 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.0 0.8 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.4 GO:0005859 muscle myosin complex(GO:0005859)
0.0 0.5 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.3 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.7 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.1 GO:0016600 flotillin complex(GO:0016600)
0.0 0.9 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 1.3 GO:0036126 sperm flagellum(GO:0036126)
0.0 1.0 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.3 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.2 GO:0071564 npBAF complex(GO:0071564)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0004903 growth hormone receptor activity(GO:0004903)
0.4 1.8 GO:0031708 endothelin B receptor binding(GO:0031708)
0.4 1.2 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
0.4 1.1 GO:0005118 sevenless binding(GO:0005118)
0.3 1.5 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.3 0.8 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.2 1.9 GO:0010385 double-stranded methylated DNA binding(GO:0010385)
0.2 0.7 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.2 1.2 GO:0004985 opioid receptor activity(GO:0004985)
0.2 1.0 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.2 0.6 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.2 0.9 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.2 0.5 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.1 0.4 GO:0034437 very-low-density lipoprotein particle binding(GO:0034189) glycoprotein transporter activity(GO:0034437)
0.1 0.6 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733)
0.1 1.5 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.1 0.4 GO:0030977 taurine binding(GO:0030977)
0.1 0.6 GO:0019863 IgE binding(GO:0019863)
0.1 0.6 GO:0032450 maltose alpha-glucosidase activity(GO:0032450)
0.1 2.8 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.5 GO:0004568 chitinase activity(GO:0004568)
0.1 0.3 GO:0004974 leukotriene receptor activity(GO:0004974)
0.1 1.0 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 1.0 GO:0034711 inhibin binding(GO:0034711)
0.1 1.5 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 0.4 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.1 0.6 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.1 0.5 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.1 1.6 GO:0030547 receptor inhibitor activity(GO:0030547)
0.1 0.9 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 0.5 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 0.2 GO:0031750 D3 dopamine receptor binding(GO:0031750) D5 dopamine receptor binding(GO:0031752)
0.1 0.3 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.1 0.6 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578) Lys48-specific deubiquitinase activity(GO:1990380)
0.1 0.7 GO:0036122 BMP binding(GO:0036122)
0.1 0.2 GO:0000401 open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402)
0.1 1.5 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.1 1.8 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.1 1.2 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.1 0.4 GO:0015245 fatty acid transporter activity(GO:0015245)
0.1 0.2 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.1 0.4 GO:0038132 neuregulin binding(GO:0038132)
0.0 0.7 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.7 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.2 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.3 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.2 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0 0.9 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)
0.0 0.2 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.6 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.3 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640)
0.0 0.1 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.0 1.4 GO:0008146 sulfotransferase activity(GO:0008146)
0.0 0.1 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 1.0 GO:0031489 myosin V binding(GO:0031489)
0.0 0.8 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.9 GO:0005521 lamin binding(GO:0005521)
0.0 1.2 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 2.2 GO:0019003 GDP binding(GO:0019003)
0.0 0.5 GO:0044548 S100 protein binding(GO:0044548)
0.0 1.1 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 0.1 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
0.0 0.2 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.2 GO:0008494 translation activator activity(GO:0008494)
0.0 0.3 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.3 GO:0097642 calcitonin family receptor activity(GO:0097642)
0.0 0.2 GO:0015198 oligopeptide transporter activity(GO:0015198)
0.0 2.2 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.1 GO:0015389 pyrimidine- and adenine-specific:sodium symporter activity(GO:0015389)
0.0 0.2 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 1.2 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.5 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.1 GO:0019770 IgG receptor activity(GO:0019770)
0.0 0.4 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.4 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.8 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.3 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.0 0.3 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.1 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.1 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.2 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.4 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.3 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.4 GO:0017127 cholesterol transporter activity(GO:0017127)
0.0 0.4 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.1 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 1.6 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.4 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.2 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 1.6 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 1.2 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 1.2 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.3 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.1 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.6 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.5 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.5 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 1.5 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 1.0 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.3 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 0.4 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.3 PID ALK2 PATHWAY ALK2 signaling events
0.0 1.0 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 1.5 PID ENDOTHELIN PATHWAY Endothelins
0.0 0.6 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 1.3 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 1.0 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 2.1 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 1.6 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.5 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.4 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.2 ST GAQ PATHWAY G alpha q Pathway
0.0 0.2 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 1.1 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.2 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.2 3.5 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 1.0 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 2.5 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.1 1.1 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 0.7 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.1 0.3 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.1 2.4 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.1 1.4 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 2.2 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 1.0 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 1.5 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.3 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.9 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.5 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 1.0 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.7 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.7 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.9 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.4 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.2 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 1.0 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 1.3 REACTOME PLC BETA MEDIATED EVENTS Genes involved in PLC beta mediated events
0.0 0.8 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.9 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.3 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.4 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 3.0 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.4 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.6 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.2 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.2 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.4 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.2 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.5 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.3 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 0.6 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.7 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.3 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.4 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.3 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.1 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.9 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.6 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.2 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.6 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions