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12D miR HR13_24

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Results for Spdef

Z-value: 1.51

Motif logo

Transcription factors associated with Spdef

Gene Symbol Gene ID Gene Info
ENSMUSG00000024215.7 SAM pointed domain containing ets transcription factor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Spdefmm10_v2_chr17_-_27728889_27728956-0.039.3e-01Click!

Activity profile of Spdef motif

Sorted Z-values of Spdef motif

Promoter Log-likelihood Transcript Gene Gene Info
chr16_+_5007283 4.52 ENSMUST00000184439.1
small integral membrane protein 22
chr16_+_5007306 3.56 ENSMUST00000178155.2
ENSMUST00000184256.1
ENSMUST00000185147.1
small integral membrane protein 22
chr12_-_84698769 3.45 ENSMUST00000095550.2
synapse differentiation inducing 1 like
chr11_+_69965396 2.78 ENSMUST00000018713.6
claudin 7
chr16_-_44016387 2.45 ENSMUST00000036174.3
GRAM domain containing 1C
chr5_+_113735782 2.35 ENSMUST00000065698.5
FIC domain containing
chr10_+_34483400 2.22 ENSMUST00000019913.7
ENSMUST00000170771.1
fyn-related kinase
chr15_-_54278420 2.09 ENSMUST00000079772.3
tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)
chr13_-_9878998 2.01 ENSMUST00000063093.9
cholinergic receptor, muscarinic 3, cardiac
chr9_+_110476985 1.98 ENSMUST00000084948.4
ENSMUST00000061155.6
ENSMUST00000140686.1
ENSMUST00000084952.5
kinesin family member 9
chrX_+_107816477 1.95 ENSMUST00000143975.1
ENSMUST00000144695.1
ENSMUST00000167154.1
family with sequence similarity 46, member D
chr7_+_141079759 1.86 ENSMUST00000066873.4
ENSMUST00000163041.1
plakophilin 3
chr8_+_105305572 1.75 ENSMUST00000109375.2
engulfment and cell motility 3
chr11_-_109722214 1.71 ENSMUST00000020938.7
family with sequence similarity 20, member A
chr2_+_129592914 1.63 ENSMUST00000103203.1
signal-regulatory protein alpha
chr2_+_129592818 1.60 ENSMUST00000153491.1
ENSMUST00000161620.1
ENSMUST00000179001.1
signal-regulatory protein alpha
chr3_-_5576233 1.59 ENSMUST00000059021.4
peroxisomal biogenesis factor 2
chr11_-_105944412 1.56 ENSMUST00000019734.4
ENSMUST00000184269.1
ENSMUST00000150563.1
cytochrome b-561
chr4_-_130279205 1.51 ENSMUST00000120126.2
serine incorporator 2
chr9_+_114978507 1.49 ENSMUST00000183104.1
oxysterol binding protein-like 10
chr3_-_5576111 1.47 ENSMUST00000165309.1
ENSMUST00000164828.1
ENSMUST00000071280.5
peroxisomal biogenesis factor 2
chr6_-_72390659 1.46 ENSMUST00000059983.9
vesicle-associated membrane protein 8
chr13_+_40886758 1.36 ENSMUST00000069958.7
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme
chr15_+_102102926 1.34 ENSMUST00000169627.1
ENSMUST00000046144.9
tensin like C1 domain-containing phosphatase
chr7_-_4546567 1.31 ENSMUST00000065957.5
synaptotagmin V
chr5_+_66968416 1.30 ENSMUST00000038188.7
LIM and calponin homology domains 1
chr11_-_119355484 1.29 ENSMUST00000100172.2
ENSMUST00000005173.4
N-sulfoglucosamine sulfohydrolase (sulfamidase)
chr4_+_45972233 1.26 ENSMUST00000102929.1
tudor domain containing 7
chr4_+_118527229 1.25 ENSMUST00000030261.5
RIKEN cDNA 2610528J11 gene
chr19_+_8920358 1.23 ENSMUST00000096243.5
beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)
chr17_-_35074485 1.13 ENSMUST00000007259.3
lymphocyte antigen 6 complex, locus G6D
chr9_-_50746501 1.12 ENSMUST00000034564.1
RIKEN cDNA 2310030G06 gene
chr5_+_117133567 1.11 ENSMUST00000179276.1
ENSMUST00000092889.5
ENSMUST00000145640.1
TAO kinase 3
chrX_+_153832225 1.11 ENSMUST00000148708.1
ENSMUST00000123264.1
ENSMUST00000049999.8
spindlin family, member 2C
chrX_+_143518576 1.11 ENSMUST00000033640.7
p21 protein (Cdc42/Rac)-activated kinase 3
chr4_+_118526986 1.11 ENSMUST00000106367.1
RIKEN cDNA 2610528J11 gene
chr1_+_135818593 1.11 ENSMUST00000038760.8
ladinin
chr19_-_6840590 1.11 ENSMUST00000170516.2
ENSMUST00000025903.5
ribosomal protein S6 kinase, polypeptide 4
chr4_-_62519885 1.10 ENSMUST00000107444.1
ENSMUST00000030090.3
aminolevulinate, delta-, dehydratase
chr1_+_58802492 1.09 ENSMUST00000165549.1
caspase 8
chr11_+_70647258 1.08 ENSMUST00000037534.7
ring finger protein 167
chr19_-_5106967 1.05 ENSMUST00000025804.5
RAB1B, member RAS oncogene family
chr8_+_105269788 1.05 ENSMUST00000036127.2
ENSMUST00000163734.2
heat shock transcription factor 4
chr1_-_121328024 1.01 ENSMUST00000003818.7
insulin induced gene 2
chr1_-_13589717 1.00 ENSMUST00000027068.4
translocating chain-associating membrane protein 1
chr8_+_72161101 0.99 ENSMUST00000003121.8
RAB8A, member RAS oncogene family
chr5_+_129941949 0.97 ENSMUST00000051758.7
ENSMUST00000073945.4
vitamin K epoxide reductase complex, subunit 1-like 1
chr15_+_88819584 0.95 ENSMUST00000024042.3
cysteine-rich with EGF-like domains 2
chr17_+_48232755 0.93 ENSMUST00000113251.3
ENSMUST00000048782.6
triggering receptor expressed on myeloid cells 1
chr9_-_110476637 0.93 ENSMUST00000111934.1
ENSMUST00000068025.6
kelch-like 18
chr8_+_105269837 0.93 ENSMUST00000172525.1
ENSMUST00000174837.1
ENSMUST00000173859.1
heat shock transcription factor 4
chr5_+_66968559 0.93 ENSMUST00000127184.1
LIM and calponin homology domains 1
chr18_-_3281036 0.93 ENSMUST00000049942.6
ENSMUST00000139537.1
ENSMUST00000124747.1
cAMP responsive element modulator
chr14_-_54253907 0.90 ENSMUST00000128231.1
defender against cell death 1
chrX_+_143518671 0.90 ENSMUST00000134402.1
p21 protein (Cdc42/Rac)-activated kinase 3
chr17_+_80290206 0.87 ENSMUST00000061703.9
MORN repeat containing 2
chr9_-_65908676 0.87 ENSMUST00000119245.1
ENSMUST00000134338.1
ENSMUST00000179395.1
thyroid hormone receptor interactor 4
chr10_-_40025253 0.87 ENSMUST00000163705.2
expressed sequence AI317395
chrX_-_8090442 0.87 ENSMUST00000033505.6
Wiskott-Aldrich syndrome homolog (human)
chr8_+_113635787 0.86 ENSMUST00000035777.8
MON1 homolog b (yeast)
chr13_+_40859768 0.86 ENSMUST00000110191.2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme
chr5_-_123865491 0.85 ENSMUST00000057145.5
niacin receptor 1
chr5_-_30907692 0.84 ENSMUST00000132034.2
ENSMUST00000132253.2
oligosaccharyltransferase 4 homolog (S. cerevisiae)
chr12_+_80644212 0.83 ENSMUST00000085245.5
solute carrier family 39 (zinc transporter), member 9
chr1_+_151755339 0.83 ENSMUST00000059498.5
ER degradation enhancer, mannosidase alpha-like 3
chr14_+_20674311 0.82 ENSMUST00000048657.8
Sec24 related gene family, member C (S. cerevisiae)
chr17_+_27057288 0.82 ENSMUST00000049308.8
inositol 1,4,5-triphosphate receptor 3
chr11_-_48817332 0.81 ENSMUST00000047145.7
tripartite motif-containing 41
chr18_-_46597480 0.81 ENSMUST00000151189.1
transmembrane emp24 protein transport domain containing 7
chr9_+_118040509 0.81 ENSMUST00000133580.1
5-azacytidine induced gene 2
chr3_-_84582616 0.81 ENSMUST00000143514.1
ADP-ribosylation factor interacting protein 1
chr3_-_63964659 0.80 ENSMUST00000161659.1
solute carrier family 33 (acetyl-CoA transporter), member 1
chr11_-_94474088 0.80 ENSMUST00000107786.1
ENSMUST00000107791.1
ENSMUST00000103166.2
ENSMUST00000107792.1
ENSMUST00000100561.3
ENSMUST00000107793.1
ENSMUST00000107788.1
ENSMUST00000107790.1
ENSMUST00000107789.1
ENSMUST00000107785.1
ENSMUST00000021234.8
calcium channel, voltage-dependent, T type, alpha 1G subunit
chr9_+_45055211 0.79 ENSMUST00000114663.2
myelin protein zero-like 3
chrX_-_75416562 0.78 ENSMUST00000033543.7
ENSMUST00000149863.2
ENSMUST00000114081.1
mature T cell proliferation 1
mature T cell proliferation 1
chr4_-_129573637 0.78 ENSMUST00000102596.1
lymphocyte protein tyrosine kinase
chr18_-_46597299 0.78 ENSMUST00000036030.7
transmembrane emp24 protein transport domain containing 7
chr10_+_127290774 0.78 ENSMUST00000026475.8
ENSMUST00000139091.1
DNA-damage inducible transcript 3
chr2_+_62664279 0.77 ENSMUST00000028257.2
grancalcin
chr5_-_29735928 0.77 ENSMUST00000065372.3
predicted gene 5129
chr3_-_89393629 0.76 ENSMUST00000124783.1
ENSMUST00000126027.1
zinc finger and BTB domain containing 7B
chr17_-_25240112 0.76 ENSMUST00000038973.6
ENSMUST00000115154.4
N-acetylglucosamine-1-phosphotransferase, gamma subunit
chr9_+_118040475 0.76 ENSMUST00000044454.5
5-azacytidine induced gene 2
chr3_+_135825788 0.75 ENSMUST00000167390.1
solute carrier family 39 (metal ion transporter), member 8
chr17_-_57247632 0.74 ENSMUST00000005975.6
G protein-coupled receptor 108
chr2_-_52742142 0.74 ENSMUST00000138290.1
signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
chr19_+_6363671 0.74 ENSMUST00000131252.1
splicing factor 1
chr3_-_89393294 0.74 ENSMUST00000142119.1
ENSMUST00000029677.8
ENSMUST00000148361.1
zinc finger and BTB domain containing 7B
chr2_+_145785980 0.73 ENSMUST00000110005.1
ENSMUST00000094480.4
Ras and Rab interactor 2
chr7_-_73537621 0.73 ENSMUST00000172704.1
chromodomain helicase DNA binding protein 2
chr17_+_32506446 0.72 ENSMUST00000165999.1
cytochrome P450, family 4, subfamily f, polypeptide 17
chr9_+_80165079 0.71 ENSMUST00000184480.1
myosin VI
chrX_-_75416533 0.71 ENSMUST00000033542.4
mature T cell proliferation 1
chr8_+_113635550 0.70 ENSMUST00000179926.1
MON1 homolog b (yeast)
chr11_+_109362771 0.69 ENSMUST00000020930.7
ENSMUST00000106702.3
guanine nucleotide binding protein, alpha 13
chr9_+_30427329 0.69 ENSMUST00000164099.1
sorting nexin 19
chrX_-_134276969 0.69 ENSMUST00000087541.5
ENSMUST00000087540.3
TRM2 tRNA methyltransferase 2B
chr11_+_21572221 0.68 ENSMUST00000020568.3
ENSMUST00000131135.1
WD repeat containing planar cell polarity effector
chr3_+_135825648 0.67 ENSMUST00000180196.1
solute carrier family 39 (metal ion transporter), member 8
chr10_-_93311073 0.67 ENSMUST00000008542.5
ELK3, member of ETS oncogene family
chr9_+_111118070 0.67 ENSMUST00000035078.6
ENSMUST00000098340.2
leucine rich repeat (in FLII) interacting protein 2
chr18_+_31609512 0.67 ENSMUST00000164667.1
RIKEN cDNA B930094E09 gene
chr17_+_28207778 0.67 ENSMUST00000002327.5
differentially expressed in FDCP 6
chr5_+_115631902 0.66 ENSMUST00000031492.8
RAB35, member RAS oncogene family
chr15_-_88819279 0.66 ENSMUST00000043087.8
ENSMUST00000162183.1
asparagine-linked glycosylation 12 (alpha-1,6-mannosyltransferase)
chr9_+_107296843 0.65 ENSMUST00000167072.1
cytokine inducible SH2-containing protein
chr10_+_95417352 0.65 ENSMUST00000181781.1
RIKEN cDNA 5730420D15 gene
chr17_-_24527925 0.65 ENSMUST00000176652.1
TNF receptor-associated factor 7
chr4_+_101647712 0.65 ENSMUST00000030254.8
leptin receptor overlapping transcript
chr13_-_22042949 0.64 ENSMUST00000091741.4
histone cluster 1, H2ag
chr11_-_58330319 0.63 ENSMUST00000065533.2
predicted gene 9900
chr8_-_70353243 0.63 ENSMUST00000075666.6
UPF1 regulator of nonsense transcripts homolog (yeast)
chr6_-_128581597 0.63 ENSMUST00000060574.7
cDNA sequence BC048546
chr6_+_29467718 0.62 ENSMUST00000004396.6
ATPase, H+ transporting, lysosomal V1 subunit F
chr4_+_101647763 0.62 ENSMUST00000106927.1
leptin receptor overlapping transcript
chr2_-_52742169 0.62 ENSMUST00000102759.1
ENSMUST00000127316.1
signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
chrX_-_134276888 0.62 ENSMUST00000113252.1
TRM2 tRNA methyltransferase 2B
chr7_+_127841752 0.61 ENSMUST00000033075.7
syntaxin 4A (placental)
chr19_+_6363719 0.61 ENSMUST00000113489.1
ENSMUST00000113488.1
splicing factor 1
chr7_+_127841817 0.61 ENSMUST00000121705.1
syntaxin 4A (placental)
chr18_-_34373313 0.61 ENSMUST00000006027.5
receptor accessory protein 5
chrX_+_101254528 0.61 ENSMUST00000062000.4
forkhead box O4
chr11_-_5542177 0.60 ENSMUST00000020776.4
coiled-coil domain containing 117
chr9_+_80165013 0.60 ENSMUST00000035889.8
ENSMUST00000113268.1
myosin VI
chr10_+_39899304 0.60 ENSMUST00000181590.1
RIKEN cDNA 4930547M16 gene
chr11_+_83302641 0.59 ENSMUST00000176430.1
ENSMUST00000065692.7
adaptor-related protein complex 2, beta 1 subunit
chr5_-_121191365 0.59 ENSMUST00000100770.2
ENSMUST00000054547.7
protein tyrosine phosphatase, non-receptor type 11
chr10_+_17723220 0.58 ENSMUST00000038107.7
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
chr9_+_107296682 0.58 ENSMUST00000168260.1
cytokine inducible SH2-containing protein
chr19_+_40894692 0.58 ENSMUST00000050092.6
zinc finger protein 518A
chr9_+_56994932 0.58 ENSMUST00000034832.6
protein tyrosine phosphatase, non-receptor type 9
chr11_-_6520894 0.58 ENSMUST00000003459.3
myosin IG
chr9_-_21918089 0.58 ENSMUST00000128442.1
ENSMUST00000119055.1
ENSMUST00000122211.1
ENSMUST00000115351.3
RAB3D, member RAS oncogene family
chr11_-_70646972 0.58 ENSMUST00000014750.8
solute carrier family 25 (mitochondrial carrier oxoglutarate carrier), member 11
chr11_-_72795801 0.57 ENSMUST00000079681.5
cytochrome b5 domain containing 2
chr11_-_48816936 0.57 ENSMUST00000140800.1
tripartite motif-containing 41
chr17_-_35979237 0.56 ENSMUST00000165613.2
ENSMUST00000173872.1
proline-rich polypeptide 3
chr9_-_88438940 0.56 ENSMUST00000165315.1
ENSMUST00000173039.1
sorting nexin 14
chr13_+_22043189 0.55 ENSMUST00000110452.1
histone cluster 1, H2bj
chr17_+_47140942 0.55 ENSMUST00000077951.7
transcriptional regulating factor 1
chr3_-_84582476 0.55 ENSMUST00000107687.2
ENSMUST00000098990.3
ADP-ribosylation factor interacting protein 1
chr9_+_45055166 0.55 ENSMUST00000114664.1
ENSMUST00000093856.3
myelin protein zero-like 3
chr17_-_24527830 0.54 ENSMUST00000176353.1
ENSMUST00000176237.1
TNF receptor-associated factor 7
chr1_+_61638819 0.54 ENSMUST00000138768.1
ENSMUST00000075374.3
par-3 partitioning defective 3 homolog B (C. elegans)
chr2_-_127541385 0.54 ENSMUST00000103214.2
prominin 2
chr4_+_43562672 0.54 ENSMUST00000167751.1
ENSMUST00000132631.1
cAMP responsive element binding protein 3
chr7_-_80232479 0.53 ENSMUST00000123279.1
calcium and integrin binding 1 (calmyrin)
chr9_-_88438898 0.53 ENSMUST00000173011.1
ENSMUST00000174806.1
sorting nexin 14
chr19_+_57361009 0.53 ENSMUST00000036407.4
family with sequence similarity 160, member B1
chr16_-_10395476 0.53 ENSMUST00000043415.6
tektin 5
chr5_+_66968961 0.52 ENSMUST00000132991.1
LIM and calponin homology domains 1
chr7_+_143473736 0.52 ENSMUST00000052348.5
solute carrier family 22 (organic cation transporter), member 18
chr4_-_101265236 0.52 ENSMUST00000149297.1
ENSMUST00000102781.3
Janus kinase 1
chr2_+_166805506 0.52 ENSMUST00000099078.3
ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
chr2_+_6322621 0.52 ENSMUST00000114937.1
USP6 N-terminal like
chr6_+_87042838 0.52 ENSMUST00000113658.1
ENSMUST00000113657.1
ENSMUST00000113655.1
ENSMUST00000032057.7
glutamine fructose-6-phosphate transaminase 1
chr18_-_10610124 0.51 ENSMUST00000097670.3
establishment of cohesion 1 homolog 1 (S. cerevisiae)
chr12_+_76533540 0.50 ENSMUST00000075249.4
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr8_+_85840971 0.50 ENSMUST00000053771.7
ENSMUST00000161850.1
phosphorylase kinase beta
chrX_-_17572241 0.50 ENSMUST00000176638.1
ENSMUST00000026016.6
FUN14 domain containing 1
chr9_+_122888471 0.49 ENSMUST00000063980.6
zinc finger with KRAB and SCAN domains 7
chr11_+_100320596 0.49 ENSMUST00000152521.1
eukaryotic translation initiation factor 1
chr15_-_9529868 0.48 ENSMUST00000003981.4
interleukin 7 receptor
chrX_+_161717498 0.48 ENSMUST00000061514.7
retinoic acid induced 2
chr1_+_95313607 0.47 ENSMUST00000059975.6
family with sequence similarity 174, member A
chr18_-_10610048 0.47 ENSMUST00000115864.1
establishment of cohesion 1 homolog 1 (S. cerevisiae)
chr11_-_116077954 0.47 ENSMUST00000106451.1
ENSMUST00000075036.2
unc-13 homolog D (C. elegans)
chr5_-_38561658 0.47 ENSMUST00000005234.9
WD repeat domain 1
chr7_-_13034722 0.47 ENSMUST00000005711.4
charged multivesicular body protein 2A
chr3_-_63964768 0.46 ENSMUST00000029402.8
solute carrier family 33 (acetyl-CoA transporter), member 1
chr8_-_83332416 0.46 ENSMUST00000177594.1
ENSMUST00000053902.3
ELMO/CED-12 domain containing 2
chr12_-_78861636 0.46 ENSMUST00000021536.7
ATPase, H+ transporting, lysosomal V1 subunit D
chr10_-_128821576 0.45 ENSMUST00000026409.3
ORM1-like 2 (S. cerevisiae)
chr11_+_83299005 0.45 ENSMUST00000176944.1
adaptor-related protein complex 2, beta 1 subunit
chr6_-_97179100 0.45 ENSMUST00000095664.3
TATA element modulatory factor 1
chr12_-_84361802 0.45 ENSMUST00000021659.1
ENSMUST00000065536.2
family with sequence similarity 161, member B
chr7_+_28440927 0.44 ENSMUST00000078845.6
glia maturation factor, gamma
chr13_-_21716143 0.44 ENSMUST00000091756.1
histone cluster 1, H2bl
chr17_-_35979679 0.44 ENSMUST00000173724.1
ENSMUST00000172900.1
ENSMUST00000174849.1
proline-rich polypeptide 3
chr2_-_26445175 0.44 ENSMUST00000114082.2
ENSMUST00000091252.4
SEC16 homolog A (S. cerevisiae)
chr2_+_152669461 0.43 ENSMUST00000125366.1
ENSMUST00000109825.1
ENSMUST00000089059.2
ENSMUST00000079247.3
histocompatibility 13
chrX_-_136085206 0.43 ENSMUST00000138878.1
ENSMUST00000080929.6
nuclear RNA export factor 3
chr19_-_40994133 0.43 ENSMUST00000117695.1
B cell linker
chr10_-_95416850 0.43 ENSMUST00000020215.9
suppressor of cytokine signaling 2
chr4_-_122886044 0.42 ENSMUST00000106255.1
ENSMUST00000106257.3
CAP, adenylate cyclase-associated protein 1 (yeast)
chr11_-_83298910 0.42 ENSMUST00000108146.1
ENSMUST00000136369.1
ENSMUST00000018877.2
peroxisomal biogenesis factor 12
chr1_-_183297008 0.42 ENSMUST00000057062.5
BRO1 domain and CAAX motif containing
chr7_+_131032061 0.42 ENSMUST00000084509.3
deleted in malignant brain tumors 1
chr6_-_120822680 0.41 ENSMUST00000019354.8
ATPase, H+ transporting, lysosomal V1 subunit E1
chr8_-_84042540 0.41 ENSMUST00000005601.7
interleukin 27 receptor, alpha
chr2_-_120850598 0.41 ENSMUST00000028740.4
tau tubulin kinase 2
chrX_-_167102059 0.41 ENSMUST00000146929.1
predicted gene 15232
chr8_-_85840877 0.41 ENSMUST00000034140.7
integrin alpha FG-GAP repeat containing 1
chr7_+_45705088 0.40 ENSMUST00000080885.3
D site albumin promoter binding protein
chr17_+_84956718 0.40 ENSMUST00000112305.3
protein phosphatase 1B, magnesium dependent, beta isoform
chr11_+_20201406 0.40 ENSMUST00000020358.5
ENSMUST00000109602.1
ENSMUST00000109601.1
RAB1, member RAS oncogene family
chr2_+_57997884 0.40 ENSMUST00000112616.1
ENSMUST00000166729.1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5
chr4_+_138972885 0.40 ENSMUST00000123636.1
ENSMUST00000043042.3
ENSMUST00000050949.2
transmembrane and coiled-coil domains 4
chr6_+_29468068 0.40 ENSMUST00000143101.1
ATPase, H+ transporting, lysosomal V1 subunit F
chr18_+_12128850 0.39 ENSMUST00000025270.6
RIO kinase 3

Network of associatons between targets according to the STRING database.

First level regulatory network of Spdef

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0019085 early viral transcription(GO:0019085)
0.5 1.5 GO:0070625 zymogen granule exocytosis(GO:0070625)
0.4 1.8 GO:0044565 dendritic cell proliferation(GO:0044565)
0.4 1.3 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.4 1.2 GO:1902568 positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.4 2.0 GO:0007207 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.4 1.5 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.4 2.2 GO:0036438 maintenance of lens transparency(GO:0036438)
0.4 1.1 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.3 1.0 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.3 1.9 GO:0002159 desmosome assembly(GO:0002159)
0.3 1.3 GO:0034421 post-translational protein acetylation(GO:0034421)
0.3 0.8 GO:2000016 negative regulation of determination of dorsal identity(GO:2000016)
0.3 0.8 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.3 1.3 GO:0060398 regulation of growth hormone receptor signaling pathway(GO:0060398)
0.2 1.2 GO:0050651 dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.2 0.7 GO:0071846 actin filament debranching(GO:0071846)
0.2 0.9 GO:2001287 negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.2 1.5 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.2 2.1 GO:0042483 negative regulation of odontogenesis(GO:0042483)
0.2 4.1 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.2 0.8 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.2 0.6 GO:2000850 negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850)
0.2 3.2 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.2 0.5 GO:0019046 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990) establishment of viral latency(GO:0019043) release from viral latency(GO:0019046)
0.2 0.5 GO:0036016 response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016)
0.2 0.5 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.2 0.8 GO:0035977 protein deglycosylation involved in glycoprotein catabolic process(GO:0035977) protein demannosylation(GO:0036507) protein alpha-1,2-demannosylation(GO:0036508) glycoprotein ERAD pathway(GO:0097466) mannose trimming involved in glycoprotein ERAD pathway(GO:1904382)
0.2 0.9 GO:0070945 neutrophil mediated killing of gram-negative bacterium(GO:0070945)
0.2 0.5 GO:1903722 regulation of centriole elongation(GO:1903722)
0.2 0.6 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.2 0.5 GO:1900060 negative regulation of ceramide biosynthetic process(GO:1900060)
0.1 0.4 GO:2000845 positive regulation of testosterone secretion(GO:2000845)
0.1 0.6 GO:0035802 adrenal cortex development(GO:0035801) adrenal cortex formation(GO:0035802) negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.1 1.3 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.1 0.4 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.1 1.4 GO:0070574 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.1 1.7 GO:0070166 enamel mineralization(GO:0070166)
0.1 0.8 GO:0050916 sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
0.1 0.7 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
0.1 0.5 GO:2000256 endomitotic cell cycle(GO:0007113) thrombopoietin-mediated signaling pathway(GO:0038163) positive regulation of male germ cell proliferation(GO:2000256)
0.1 0.4 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.1 0.6 GO:0032201 telomere maintenance via semi-conservative replication(GO:0032201)
0.1 0.5 GO:0030043 actin filament fragmentation(GO:0030043)
0.1 0.6 GO:0038094 Fc-gamma receptor signaling pathway(GO:0038094)
0.1 0.6 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.1 3.6 GO:0006910 phagocytosis, recognition(GO:0006910)
0.1 2.2 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.1 0.7 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.1 1.1 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.1 0.8 GO:0002432 granuloma formation(GO:0002432)
0.1 0.2 GO:0070668 mast cell proliferation(GO:0070662) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.1 0.5 GO:0006041 glucosamine metabolic process(GO:0006041)
0.1 0.6 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.1 0.2 GO:0060599 lateral sprouting involved in mammary gland duct morphogenesis(GO:0060599)
0.1 0.8 GO:0061143 alveolar primary septum development(GO:0061143)
0.1 1.3 GO:0071257 cellular response to electrical stimulus(GO:0071257)
0.1 1.2 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 0.3 GO:0090611 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837) ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.1 2.0 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.1 1.0 GO:0045588 positive regulation of gamma-delta T cell differentiation(GO:0045588) positive regulation of gamma-delta T cell activation(GO:0046645)
0.1 1.4 GO:0033327 Leydig cell differentiation(GO:0033327)
0.1 0.3 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.1 0.2 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.1 0.7 GO:0002756 MyD88-independent toll-like receptor signaling pathway(GO:0002756)
0.1 2.0 GO:0010763 positive regulation of fibroblast migration(GO:0010763)
0.1 0.6 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.1 0.4 GO:0010626 negative regulation of Schwann cell proliferation(GO:0010626)
0.1 0.9 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.1 1.0 GO:0060363 cranial suture morphogenesis(GO:0060363)
0.1 2.0 GO:0071801 regulation of podosome assembly(GO:0071801)
0.1 0.7 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.1 0.6 GO:0071397 cellular response to cholesterol(GO:0071397)
0.1 0.2 GO:0046381 CMP-N-acetylneuraminate metabolic process(GO:0046381)
0.1 0.7 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.1 1.0 GO:1903540 neurotransmitter receptor transport to plasma membrane(GO:0098877) neurotransmitter receptor transport to postsynaptic membrane(GO:0098969) establishment of protein localization to postsynaptic membrane(GO:1903540)
0.1 0.2 GO:1904959 regulation of electron carrier activity(GO:1904732) regulation of cytochrome-c oxidase activity(GO:1904959)
0.1 0.4 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.1 1.1 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.1 0.8 GO:0035278 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.2 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 0.3 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.2 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.0 1.1 GO:0095500 acetylcholine receptor signaling pathway(GO:0095500) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.0 0.1 GO:2000872 positive regulation of progesterone secretion(GO:2000872)
0.0 0.3 GO:0006499 N-terminal protein myristoylation(GO:0006499)
0.0 0.2 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.2 GO:0043652 engulfment of apoptotic cell(GO:0043652)
0.0 0.7 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.0 0.3 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.0 0.1 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.0 1.2 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 1.1 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.2 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.4 GO:0071378 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.0 1.3 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 1.1 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 0.2 GO:0051715 cytolysis in other organism(GO:0051715)
0.0 0.2 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0 1.1 GO:1903020 positive regulation of glycoprotein metabolic process(GO:1903020)
0.0 0.4 GO:1990403 embryonic brain development(GO:1990403)
0.0 1.3 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.7 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 0.5 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.1 GO:1905077 negative regulation of interleukin-17 secretion(GO:1905077)
0.0 0.4 GO:0002829 negative regulation of type 2 immune response(GO:0002829)
0.0 0.2 GO:0042473 outer ear morphogenesis(GO:0042473)
0.0 0.1 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.0 0.2 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.0 0.4 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 2.3 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 0.3 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)
0.0 0.1 GO:2000437 monocyte extravasation(GO:0035696) regulation of monocyte extravasation(GO:2000437) positive regulation of monocyte extravasation(GO:2000439)
0.0 0.1 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.0 0.1 GO:0021506 anterior neuropore closure(GO:0021506) neuropore closure(GO:0021995)
0.0 0.3 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.3 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.0 0.4 GO:0031937 positive regulation of chromatin silencing(GO:0031937)
0.0 0.4 GO:0098543 detection of bacterium(GO:0016045) pyroptosis(GO:0070269) detection of other organism(GO:0098543)
0.0 0.4 GO:0033008 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.0 0.3 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.4 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.8 GO:0006829 zinc II ion transport(GO:0006829)
0.0 0.1 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 0.4 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.3 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0 0.2 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.2 GO:0043415 positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.0 0.1 GO:0006172 ADP biosynthetic process(GO:0006172)
0.0 0.4 GO:0002446 neutrophil mediated immunity(GO:0002446)
0.0 0.2 GO:0031145 anaphase-promoting complex-dependent catabolic process(GO:0031145)
0.0 0.9 GO:0030520 intracellular estrogen receptor signaling pathway(GO:0030520)
0.0 0.5 GO:0072673 lamellipodium morphogenesis(GO:0072673)
0.0 0.2 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.9 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.0 0.1 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.2 GO:0090148 membrane fission(GO:0090148)
0.0 0.3 GO:0006691 leukotriene metabolic process(GO:0006691)
0.0 0.1 GO:0071955 recycling endosome to Golgi transport(GO:0071955)
0.0 0.1 GO:0032811 negative regulation of gamma-aminobutyric acid secretion(GO:0014053) negative regulation of epinephrine secretion(GO:0032811)
0.0 0.2 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.0 0.1 GO:0072015 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.0 0.2 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.0 0.3 GO:0006903 vesicle targeting(GO:0006903)
0.0 0.7 GO:0045761 regulation of adenylate cyclase activity(GO:0045761)
0.0 0.5 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.2 GO:0043372 positive regulation of CD4-positive, alpha-beta T cell differentiation(GO:0043372)
0.0 0.1 GO:0018202 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183) peptidyl-histidine modification(GO:0018202)
0.0 0.3 GO:0005980 glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.0 1.7 GO:0006909 phagocytosis(GO:0006909)
0.0 0.6 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 0.5 GO:0015893 drug transport(GO:0015893)
0.0 0.8 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 0.3 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.0 0.1 GO:0032471 negative regulation of endoplasmic reticulum calcium ion concentration(GO:0032471)
0.0 0.5 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.6 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.2 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.0 0.5 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 0.5 GO:0061512 protein localization to cilium(GO:0061512)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.9 GO:0005914 spot adherens junction(GO:0005914)
0.4 1.1 GO:0030690 Noc1p-Noc2p complex(GO:0030690)
0.3 3.1 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.3 1.3 GO:1990769 proximal neuron projection(GO:1990769)
0.3 0.8 GO:0036488 CHOP-C/EBP complex(GO:0036488)
0.3 1.0 GO:1990415 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.2 0.9 GO:0044393 microspike(GO:0044393)
0.2 1.2 GO:0000322 storage vacuole(GO:0000322)
0.2 0.5 GO:0032280 symmetric synapse(GO:0032280)
0.2 1.9 GO:0005766 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.1 0.4 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.1 1.0 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 0.5 GO:0035339 SPOTS complex(GO:0035339)
0.1 2.8 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 0.3 GO:0000814 ESCRT II complex(GO:0000814)
0.1 0.6 GO:0044530 supraspliceosomal complex(GO:0044530)
0.1 2.0 GO:0032279 asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.1 0.4 GO:0071797 LUBAC complex(GO:0071797)
0.1 1.0 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1 0.4 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.1 0.8 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 1.3 GO:0033391 chromatoid body(GO:0033391)
0.1 0.5 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.1 1.1 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 0.4 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.1 0.2 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
0.1 0.3 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.1 2.0 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.1 0.9 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 1.2 GO:0001891 phagocytic cup(GO:0001891)
0.1 0.4 GO:0072557 IPAF inflammasome complex(GO:0072557)
0.1 0.8 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 1.1 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.2 GO:0017133 mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
0.0 0.3 GO:0019815 B cell receptor complex(GO:0019815)
0.0 0.5 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.3 GO:0097441 basilar dendrite(GO:0097441)
0.0 1.6 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 2.0 GO:0002102 podosome(GO:0002102)
0.0 0.2 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.0 0.5 GO:0031209 SCAR complex(GO:0031209)
0.0 0.2 GO:0005955 calcineurin complex(GO:0005955)
0.0 1.0 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.8 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.8 GO:0042588 zymogen granule(GO:0042588)
0.0 1.6 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.9 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.2 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.7 GO:0005839 proteasome core complex(GO:0005839)
0.0 1.6 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.3 GO:0089701 U2AF(GO:0089701)
0.0 0.3 GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)
0.0 0.6 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.5 GO:0032433 filopodium tip(GO:0032433)
0.0 0.2 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.6 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 1.1 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.3 GO:0090543 Flemming body(GO:0090543)
0.0 0.7 GO:0044447 axoneme part(GO:0044447)
0.0 0.3 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.1 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.0 0.2 GO:0036452 ESCRT complex(GO:0036452)
0.0 0.2 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.5 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.2 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.3 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 1.3 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 1.0 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.4 GO:0035869 ciliary transition zone(GO:0035869)
0.0 0.2 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.2 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 1.7 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.2 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.5 1.6 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
0.4 2.0 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.3 1.4 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.3 1.2 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.3 1.1 GO:0035877 death effector domain binding(GO:0035877)
0.2 1.2 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.2 1.3 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.2 0.8 GO:0000822 inositol hexakisphosphate binding(GO:0000822) inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.2 0.8 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.2 0.6 GO:0015140 malate transmembrane transporter activity(GO:0015140)
0.2 0.8 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.2 0.5 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.2 1.0 GO:0051185 coenzyme transporter activity(GO:0051185)
0.2 0.7 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.2 0.8 GO:0042610 CD8 receptor binding(GO:0042610)
0.2 0.5 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.1 1.1 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.1 0.9 GO:0005131 growth hormone receptor binding(GO:0005131)
0.1 1.9 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 0.3 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.1 1.5 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.1 0.5 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.1 0.4 GO:0030348 syntaxin-3 binding(GO:0030348)
0.1 2.0 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.1 0.8 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 0.3 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.1 1.3 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.1 0.6 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1 0.2 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 0.4 GO:0089720 caspase binding(GO:0089720)
0.1 0.2 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.1 0.8 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 0.9 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.1 0.5 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.1 0.2 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.1 1.2 GO:0048038 quinone binding(GO:0048038)
0.1 0.2 GO:0005110 frizzled-2 binding(GO:0005110)
0.1 2.1 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 1.6 GO:0031489 myosin V binding(GO:0031489)
0.1 0.8 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 1.9 GO:0070566 adenylyltransferase activity(GO:0070566)
0.1 0.2 GO:0016501 prostacyclin receptor activity(GO:0016501)
0.1 0.2 GO:0097003 adipokinetic hormone receptor activity(GO:0097003)
0.1 0.7 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 0.4 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 0.2 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.1 2.7 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 1.1 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.1 0.4 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.1 1.7 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.2 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.0 1.4 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 3.3 GO:0045309 protein phosphorylated amino acid binding(GO:0045309)
0.0 1.2 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 1.4 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.7 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.2 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.0 1.1 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.1 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.0 0.2 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 2.3 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.1 GO:0001888 glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0001888)
0.0 0.4 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.6 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.5 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.3 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.2 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.3 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.7 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.5 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.0 0.3 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.0 0.9 GO:0043274 phospholipase binding(GO:0043274)
0.0 0.7 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.2 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.6 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 1.5 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.8 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.2 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.4 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 1.5 GO:0030276 clathrin binding(GO:0030276)
0.0 0.1 GO:0031711 bradykinin receptor binding(GO:0031711)
0.0 0.2 GO:0070513 death domain binding(GO:0070513)
0.0 0.2 GO:1903136 copper chaperone activity(GO:0016531) cuprous ion binding(GO:1903136)
0.0 0.4 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.2 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.2 GO:0051022 Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0 0.4 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.3 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.3 GO:1990381 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264) ubiquitin-specific protease binding(GO:1990381)
0.0 0.6 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.4 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.5 GO:0015238 drug transmembrane transporter activity(GO:0015238)
0.0 0.2 GO:0046790 virion binding(GO:0046790)
0.0 1.0 GO:0016836 hydro-lyase activity(GO:0016836)
0.0 0.3 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445) inositol trisphosphate phosphatase activity(GO:0046030)
0.0 0.8 GO:0051183 vitamin transporter activity(GO:0051183)
0.0 0.1 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578) Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.4 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.3 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.2 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.4 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.8 GO:0061733 peptide-lysine-N-acetyltransferase activity(GO:0061733)
0.0 0.1 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.4 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.1 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 1.3 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 1.6 GO:0019903 protein phosphatase binding(GO:0019903)
0.0 0.2 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 1.1 GO:0000149 SNARE binding(GO:0000149)
0.0 1.6 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.4 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.4 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.8 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.1 1.1 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 3.2 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.1 1.1 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.8 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.7 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 1.3 PID AURORA A PATHWAY Aurora A signaling
0.0 0.8 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.2 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 1.1 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 1.6 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.5 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 1.6 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.4 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.6 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.5 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.6 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.8 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.3 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.2 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 0.8 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.4 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.6 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.5 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.7 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.2 2.1 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.2 3.2 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 1.3 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.1 0.8 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 0.8 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 1.1 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 0.8 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1 0.8 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 2.0 REACTOME KINESINS Genes involved in Kinesins
0.1 1.2 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 1.3 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.1 1.2 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.1 1.9 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.1 2.8 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 1.4 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 1.3 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.1 0.5 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.1 0.9 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 1.8 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.9 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 1.1 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 1.1 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.8 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 1.2 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 1.3 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.4 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.4 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.8 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.8 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.0 0.4 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0 1.2 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.7 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.2 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.8 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 1.1 REACTOME ASPARAGINE N LINKED GLYCOSYLATION Genes involved in Asparagine N-linked glycosylation
0.0 0.6 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 0.3 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.2 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.0 0.2 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.2 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.0 0.9 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall