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12D miR HR13_24

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Results for Irf2_Irf1_Irf8_Irf9_Irf7

Z-value: 2.09

Motif logo

Transcription factors associated with Irf2_Irf1_Irf8_Irf9_Irf7

Gene Symbol Gene ID Gene Info
ENSMUSG00000031627.7 interferon regulatory factor 2
ENSMUSG00000018899.10 interferon regulatory factor 1
ENSMUSG00000041515.3 interferon regulatory factor 8
ENSMUSG00000002325.8 interferon regulatory factor 9
ENSMUSG00000025498.8 interferon regulatory factor 7

Activity-expression correlation:

Activity profile of Irf2_Irf1_Irf8_Irf9_Irf7 motif

Sorted Z-values of Irf2_Irf1_Irf8_Irf9_Irf7 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr8_+_61928081 5.73 ENSMUST00000154398.1
ENSMUST00000093485.2
ENSMUST00000156980.1
ENSMUST00000070631.7
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
chr3_-_113574242 4.62 ENSMUST00000142505.2
amylase 1, salivary
chr3_-_113574758 4.12 ENSMUST00000106540.1
amylase 1, salivary
chr7_+_104244496 3.79 ENSMUST00000106854.1
ENSMUST00000143414.1
tripartite motif-containing 34A
chr7_+_104244449 3.78 ENSMUST00000106849.2
ENSMUST00000060315.5
tripartite motif-containing 34A
chr7_+_104244465 3.61 ENSMUST00000106848.1
tripartite motif-containing 34A
chr19_+_34640871 3.47 ENSMUST00000102824.3
interferon-induced protein with tetratricopeptide repeats 1
chr12_-_79007276 3.45 ENSMUST00000056660.6
ENSMUST00000174721.1
transmembrane protein 229B
chr5_-_92348871 2.94 ENSMUST00000038816.6
ENSMUST00000118006.1
chemokine (C-X-C motif) ligand 10
chr8_-_105938384 2.75 ENSMUST00000034369.8
proteasome (prosome, macropain) subunit, beta type 10
chr5_-_105239533 2.57 ENSMUST00000065588.6
guanylate-binding protein 10
chr4_-_40239779 2.18 ENSMUST00000037907.6
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr7_+_78913765 2.07 ENSMUST00000038142.8
interferon-stimulated protein
chr12_-_78980758 2.03 ENSMUST00000174072.1
transmembrane protein 229B
chr1_-_156674290 1.98 ENSMUST00000079625.4
torsin family 3, member A
chr4_-_40239700 1.97 ENSMUST00000142055.1
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr19_+_34607927 1.93 ENSMUST00000076249.5
RIKEN cDNA I830012O16 gene
chr17_+_33919332 1.90 ENSMUST00000025161.7
TAP binding protein
chr19_+_29367447 1.88 ENSMUST00000016640.7
CD274 antigen
chr3_+_142620596 1.87 ENSMUST00000165774.1
guanylate binding protein 2
chr10_-_75797728 1.82 ENSMUST00000139724.1
glutathione S-transferase, theta 1
chr15_+_9436028 1.80 ENSMUST00000042360.3
calcyphosine-like
chr19_+_55741810 1.78 ENSMUST00000111657.3
ENSMUST00000061496.9
ENSMUST00000041717.7
ENSMUST00000111662.4
transcription factor 7 like 2, T cell specific, HMG box
chr12_+_26469204 1.78 ENSMUST00000020969.3
cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
chr8_-_111338152 1.73 ENSMUST00000056157.7
ENSMUST00000120432.1
mixed lineage kinase domain-like
chr5_+_117357274 1.73 ENSMUST00000031309.9
WD repeat and SOCS box-containing 2
chr2_-_103283760 1.70 ENSMUST00000111174.1
ets homologous factor
chr9_+_5298517 1.65 ENSMUST00000027015.5
caspase 1
chr17_-_36042690 1.64 ENSMUST00000058801.8
ENSMUST00000080015.5
ENSMUST00000077960.6
histocompatibility 2, T region locus 22
chr4_-_42773993 1.63 ENSMUST00000095114.4
chemokine (C-C motif) ligand 21A (serine)
chr11_+_29718563 1.62 ENSMUST00000060992.5
reticulon 4
chr4_+_42255767 1.59 ENSMUST00000178864.1
chemokine (C-C motif) ligand 21B (leucine)
chr5_-_105293699 1.59 ENSMUST00000050011.8
guanylate binding protein 6
chr2_-_51972990 1.58 ENSMUST00000145481.1
ENSMUST00000112705.2
N-myc (and STAT) interactor
chr8_+_64947177 1.58 ENSMUST00000079896.7
ENSMUST00000026595.5
transmembrane protein 192
chr12_-_26456423 1.54 ENSMUST00000020970.7
radical S-adenosyl methionine domain containing 2
chr15_-_98728120 1.53 ENSMUST00000003445.6
FK506 binding protein 11
chr6_+_39381175 1.50 ENSMUST00000031986.4
RAB19, member RAS oncogene family
chr6_-_125231772 1.50 ENSMUST00000043422.7
TAP binding protein-like
chr1_+_52119438 1.49 ENSMUST00000070968.7
signal transducer and activator of transcription 1
chr4_+_45972233 1.48 ENSMUST00000102929.1
tudor domain containing 7
chr6_-_39118211 1.45 ENSMUST00000038398.6
poly (ADP-ribose) polymerase family, member 12
chr17_-_34187219 1.42 ENSMUST00000173831.1
proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)
chr19_+_22692613 1.42 ENSMUST00000099564.2
ENSMUST00000099566.3
transient receptor potential cation channel, subfamily M, member 3
chr4_-_145246855 1.38 ENSMUST00000030336.4
tumor necrosis factor receptor superfamily, member 1b
chr14_+_41105359 1.35 ENSMUST00000047286.6
methionine adenosyltransferase I, alpha
chr16_-_24393588 1.35 ENSMUST00000181640.1
RIKEN cDNA 1110054M08 gene
chr3_+_142560351 1.34 ENSMUST00000106221.1
guanylate binding protein 3
chr9_+_107975529 1.34 ENSMUST00000035216.4
ubiquitin-like modifier activating enzyme 7
chr1_+_16688405 1.32 ENSMUST00000026881.4
lymphocyte antigen 96
chr3_+_142560108 1.31 ENSMUST00000128609.1
ENSMUST00000029935.7
guanylate binding protein 3
chr7_-_102565425 1.31 ENSMUST00000106913.1
ENSMUST00000033264.4
tripartite motif-containing 21
chr7_-_141266415 1.29 ENSMUST00000106023.1
ENSMUST00000097952.2
ENSMUST00000026571.4
interferon regulatory factor 7
chr15_+_99392882 1.29 ENSMUST00000023749.8
transmembrane BAX inhibitor motif containing 6
chr1_+_153751859 1.26 ENSMUST00000182538.1
ribonuclease L (2', 5'-oligoisoadenylate synthetase-dependent)
chr16_+_23609895 1.25 ENSMUST00000038423.5
receptor transporter protein 4
chr7_-_104353328 1.24 ENSMUST00000130139.1
ENSMUST00000059037.8
tripartite motif-containing 12C
chr7_+_78914216 1.19 ENSMUST00000120331.2
interferon-stimulated protein
chr10_+_128270546 1.18 ENSMUST00000105238.3
ENSMUST00000085708.2
signal transducer and activator of transcription 2
chr1_+_130826676 1.17 ENSMUST00000027675.7
polymeric immunoglobulin receptor
chr11_+_101582236 1.16 ENSMUST00000039581.7
ENSMUST00000100403.2
ENSMUST00000107194.1
ENSMUST00000128614.1
transmembrane protein 106A
chr5_-_120749848 1.14 ENSMUST00000053909.6
ENSMUST00000081491.6
2'-5' oligoadenylate synthetase 2
chr2_+_24385313 1.13 ENSMUST00000056641.8
pleckstrin and Sec7 domain containing 4
chr5_+_117319292 1.12 ENSMUST00000086464.4
V-set and immunoglobulin domain containing 10
chr1_-_155146755 1.12 ENSMUST00000027744.8
major histocompatibility complex, class I-related
chr3_+_142560052 1.11 ENSMUST00000106222.2
guanylate binding protein 3
chr17_-_34862473 1.07 ENSMUST00000025229.4
ENSMUST00000176203.2
ENSMUST00000128767.1
complement factor B
chr9_+_38718263 1.06 ENSMUST00000001544.5
ENSMUST00000118144.1
von Willebrand factor A domain containing 5A
chr13_+_23738804 1.05 ENSMUST00000040914.1
histone cluster 1, H1c
chr11_+_69964758 1.04 ENSMUST00000108597.1
ENSMUST00000060651.5
ENSMUST00000108596.1
claudin 7
chr2_-_62646146 1.03 ENSMUST00000112459.3
ENSMUST00000028259.5
interferon induced with helicase C domain 1
chr2_-_51973219 1.01 ENSMUST00000028314.2
N-myc (and STAT) interactor
chr6_+_96113146 0.99 ENSMUST00000122120.1
family with sequence similarity 19, member A1
chr11_+_114851142 0.99 ENSMUST00000133245.1
ENSMUST00000122967.2
G protein-coupled receptor, family C, group 5, member C
chr11_-_48871344 0.99 ENSMUST00000049519.3
immunity-related GTPase family M member 1
chr1_+_130826762 0.99 ENSMUST00000133792.1
polymeric immunoglobulin receptor
chr4_-_46536134 0.98 ENSMUST00000046897.6
tripartite motif-containing 14
chr2_-_51934644 0.98 ENSMUST00000165313.1
RNA binding motif protein 43
chr2_-_51934943 0.97 ENSMUST00000102767.1
ENSMUST00000102768.1
RNA binding motif protein 43
chr13_+_56609516 0.97 ENSMUST00000045173.8
transforming growth factor, beta induced
chr5_-_117319242 0.97 ENSMUST00000100834.1
predicted gene 10399
chr3_+_27317028 0.97 ENSMUST00000046383.5
ENSMUST00000174840.1
tumor necrosis factor (ligand) superfamily, member 10
chr5_+_114896936 0.96 ENSMUST00000031542.9
ENSMUST00000146072.1
ENSMUST00000150361.1
2'-5' oligoadenylate synthetase-like 2
chr2_+_122147680 0.96 ENSMUST00000102476.4
beta-2 microglobulin
chr7_+_97453204 0.95 ENSMUST00000050732.7
ENSMUST00000121987.1
potassium channel tetramerisation domain containing 14
chr17_-_34862122 0.95 ENSMUST00000154526.1
complement factor B
chr4_+_41903610 0.95 ENSMUST00000098128.3
predicted gene, 21541
chr6_-_54972603 0.95 ENSMUST00000060655.8
nucleotide-binding oligomerization domain containing 1
chr13_+_33004528 0.94 ENSMUST00000006391.4
serine (or cysteine) peptidase inhibitor, clade B, member 9
chr4_+_42114817 0.93 ENSMUST00000098123.3
predicted gene 13304
chr2_+_58755177 0.92 ENSMUST00000102755.3
uridine phosphorylase 2
chr5_+_117319258 0.92 ENSMUST00000111967.1
V-set and immunoglobulin domain containing 10
chr5_-_134229581 0.92 ENSMUST00000111275.1
ENSMUST00000016094.6
ENSMUST00000144086.1
neutrophil cytosolic factor 1
chr5_+_147269959 0.91 ENSMUST00000085591.5
pancreatic and duodenal homeobox 1
chr11_+_58199556 0.90 ENSMUST00000035266.4
ENSMUST00000094169.4
ENSMUST00000168280.1
ENSMUST00000058704.8
interferon gamma induced GTPase
immunity-related GTPase family M member 2
chr7_+_51878967 0.89 ENSMUST00000051912.6
growth arrest specific 2
chr1_+_58711488 0.89 ENSMUST00000097722.2
ENSMUST00000114313.1
CASP8 and FADD-like apoptosis regulator
chr8_+_127064107 0.89 ENSMUST00000162536.1
ENSMUST00000026921.6
ENSMUST00000162665.1
ENSMUST00000160766.1
ENSMUST00000162602.1
ENSMUST00000162531.1
ENSMUST00000160581.1
ENSMUST00000161355.1
ENSMUST00000159537.1
par-3 (partitioning defective 3) homolog (C. elegans)
chr3_-_137981523 0.89 ENSMUST00000136613.1
ENSMUST00000029806.6
dual adaptor for phosphotyrosine and 3-phosphoinositides 1
chr3_+_68691424 0.89 ENSMUST00000107816.2
interleukin 12a
chr18_-_61536522 0.87 ENSMUST00000171629.1
Rho guanine nucleotide exchange factor (GEF) 37
chr11_-_49064202 0.87 ENSMUST00000046745.6
T cell specific GTPase 2
chr19_-_11050500 0.86 ENSMUST00000099676.4
expressed sequence AW112010
chr16_-_97462903 0.85 ENSMUST00000142883.1
ENSMUST00000113768.1
ENSMUST00000023655.6
myxovirus (influenza virus) resistance 1
chr4_+_102589687 0.84 ENSMUST00000097949.4
ENSMUST00000106901.1
phosphodiesterase 4B, cAMP specific
chr16_+_35938470 0.84 ENSMUST00000114878.1
poly (ADP-ribose) polymerase family, member 9
chr1_+_153751946 0.83 ENSMUST00000183241.1
ribonuclease L (2', 5'-oligoisoadenylate synthetase-dependent)
chr9_-_45204083 0.83 ENSMUST00000034599.8
transmembrane protease, serine 4
chr7_-_45238794 0.83 ENSMUST00000098461.1
ENSMUST00000107797.1
CD37 antigen
chr7_+_51879041 0.83 ENSMUST00000107591.2
growth arrest specific 2
chr13_+_51846673 0.82 ENSMUST00000021903.2
growth arrest and DNA-damage-inducible 45 gamma
chr11_-_100704217 0.81 ENSMUST00000017974.6
DEXH (Asp-Glu-X-His) box polypeptide 58
chr11_-_48992226 0.80 ENSMUST00000059930.2
ENSMUST00000068063.3
predicted gene 12185
T cell specific GTPase 1
chr11_-_48871408 0.79 ENSMUST00000097271.2
immunity-related GTPase family M member 1
chr2_-_24049389 0.78 ENSMUST00000051416.5
histamine N-methyltransferase
chr9_-_111057235 0.78 ENSMUST00000111888.1
chemokine (C-C motif) receptor-like 2
chr4_+_111719975 0.77 ENSMUST00000038868.7
ENSMUST00000070513.6
ENSMUST00000153746.1
spermatogenesis associated 6
chr5_-_120907510 0.77 ENSMUST00000080322.7
2'-5' oligoadenylate synthetase 1A
chr4_+_111720187 0.76 ENSMUST00000084354.3
spermatogenesis associated 6
chr2_+_58754910 0.76 ENSMUST00000059102.6
uridine phosphorylase 2
chr19_+_6164433 0.75 ENSMUST00000045042.7
basic leucine zipper transcription factor, ATF-like 2
chr3_+_60081861 0.75 ENSMUST00000029326.5
succinate receptor 1
chr3_+_106482427 0.75 ENSMUST00000029508.4
DENN/MADD domain containing 2D
chr11_+_58215028 0.74 ENSMUST00000108836.1
immunity-related GTPase family M member 2
chr16_+_97536079 0.73 ENSMUST00000024112.7
myxovirus (influenza virus) resistance 2
chr12_+_52699297 0.73 ENSMUST00000095737.3
A kinase (PRKA) anchor protein 6
chr12_+_103434211 0.73 ENSMUST00000079294.5
ENSMUST00000076788.5
ENSMUST00000076702.5
ENSMUST00000066701.6
ENSMUST00000085065.5
ENSMUST00000140838.1
interferon, alpha-inducible protein 27
chr6_-_34955903 0.72 ENSMUST00000147169.1
RIKEN cDNA 2010107G12 gene
chr9_+_118040475 0.72 ENSMUST00000044454.5
5-azacytidine induced gene 2
chr5_+_114923234 0.72 ENSMUST00000031540.4
ENSMUST00000112143.3
2'-5' oligoadenylate synthetase-like 1
chr1_-_174031712 0.71 ENSMUST00000059226.6
interferon activated gene 205
chr14_-_26066961 0.71 ENSMUST00000100818.5
transmembrane protein 254c
chr10_+_116177351 0.70 ENSMUST00000155606.1
ENSMUST00000128399.1
protein tyrosine phosphatase, receptor type, R
chr1_-_156036473 0.70 ENSMUST00000097527.3
ENSMUST00000027738.7
torsin A interacting protein 1
chr5_+_35056813 0.70 ENSMUST00000101298.2
ENSMUST00000114270.1
ENSMUST00000133381.1
docking protein 7
chr4_+_54947976 0.70 ENSMUST00000098070.3
zinc finger protein 462
chr10_+_116177217 0.69 ENSMUST00000148731.1
protein tyrosine phosphatase, receptor type, R
chr16_+_35938972 0.68 ENSMUST00000023622.6
ENSMUST00000114877.1
poly (ADP-ribose) polymerase family, member 9
chr14_+_30716377 0.68 ENSMUST00000112177.1
Scm-like with four mbt domains 1
chr6_+_34863130 0.68 ENSMUST00000074949.3
transmembrane protein 140
chr11_+_61065798 0.67 ENSMUST00000041944.2
ENSMUST00000108717.2
potassium inwardly-rectifying channel, subfamily J, member 12
chr13_+_42866247 0.67 ENSMUST00000131942.1
phosphatase and actin regulator 1
chrX_-_9469288 0.67 ENSMUST00000015484.3
cytochrome b-245, beta polypeptide
chr18_+_37264998 0.67 ENSMUST00000052366.3
protocadherin beta 1
chr13_-_23710714 0.67 ENSMUST00000091707.6
ENSMUST00000006787.7
ENSMUST00000091706.6
hemochromatosis
chr18_-_60273267 0.67 ENSMUST00000090260.4
predicted gene 4841
chr5_-_65492984 0.66 ENSMUST00000139122.1
small integral membrane protein 14
chr19_+_36409719 0.66 ENSMUST00000062389.5
polycomb group ring finger 5
chr11_-_47379405 0.66 ENSMUST00000077221.5
sarcoglycan, delta (dystrophin-associated glycoprotein)
chr1_+_61638819 0.65 ENSMUST00000138768.1
ENSMUST00000075374.3
par-3 partitioning defective 3 homolog B (C. elegans)
chr9_+_118040509 0.65 ENSMUST00000133580.1
5-azacytidine induced gene 2
chr1_-_69685937 0.64 ENSMUST00000027146.2
IKAROS family zinc finger 2
chr18_-_3299537 0.63 ENSMUST00000129435.1
ENSMUST00000122958.1
cAMP responsive element modulator
chr15_+_83563571 0.62 ENSMUST00000047419.6
translocator protein
chr15_+_57694651 0.62 ENSMUST00000096430.4
zinc fingers and homeoboxes 2
chr11_+_3989924 0.62 ENSMUST00000109981.1
galactose-3-O-sulfotransferase 1
chr10_-_88356990 0.61 ENSMUST00000020249.1
DNA-damage regulated autophagy modulator 1
chr14_+_77904365 0.61 ENSMUST00000169978.1
epithelial stromal interaction 1 (breast)
chr18_-_3299452 0.61 ENSMUST00000126578.1
cAMP responsive element modulator
chr6_-_38354243 0.61 ENSMUST00000114900.1
zinc finger CCCH type, antiviral 1
chr18_+_60376029 0.61 ENSMUST00000066912.5
ENSMUST00000032473.6
interferon inducible GTPase 1
chr11_-_102296618 0.60 ENSMUST00000107132.2
ENSMUST00000073234.2
ataxin 7-like 3
chr4_+_138972885 0.60 ENSMUST00000123636.1
ENSMUST00000043042.3
ENSMUST00000050949.2
transmembrane and coiled-coil domains 4
chrX_+_144688907 0.60 ENSMUST00000112843.1
zinc finger, CCHC domain containing 16
chr10_+_78069351 0.60 ENSMUST00000105393.1
icos ligand
chr6_-_3399545 0.60 ENSMUST00000120087.3
sterile alpha motif domain containing 9-like
chr17_+_30901811 0.59 ENSMUST00000114574.1
glucagon-like peptide 1 receptor
chr5_-_52471534 0.59 ENSMUST00000059428.5
coiled-coil domain containing 149
chr7_-_45239108 0.59 ENSMUST00000033063.6
CD37 antigen
chr16_+_24393350 0.58 ENSMUST00000038053.6
LIM domain containing preferred translocation partner in lipoma
chr8_+_83165348 0.58 ENSMUST00000034145.4
TBC1 domain family, member 9
chr3_+_142530329 0.57 ENSMUST00000171263.1
ENSMUST00000045097.9
guanylate binding protein 7
chr15_+_99392948 0.57 ENSMUST00000161250.1
ENSMUST00000160635.1
ENSMUST00000161778.1
transmembrane BAX inhibitor motif containing 6
chrX_-_104857228 0.57 ENSMUST00000033575.5
melanoma antigen, family E, 2
chr9_-_14381242 0.56 ENSMUST00000167549.1
endonuclease domain containing 1
chr10_+_39612934 0.55 ENSMUST00000019987.6
TRAF3 interacting protein 2
chr6_+_41521782 0.55 ENSMUST00000070380.4
protease, serine, 2
chr3_+_95526777 0.54 ENSMUST00000015667.2
ENSMUST00000116304.2
cathepsin S
chr8_+_35375719 0.54 ENSMUST00000070481.6
protein phosphatase 1, regulatory (inhibitor) subunit 3B
chr18_+_37447641 0.54 ENSMUST00000052387.3
protocadherin beta 14
chr9_-_15045378 0.54 ENSMUST00000164273.1
pannexin 1
chr3_-_88372740 0.54 ENSMUST00000107543.1
ENSMUST00000107542.1
bone gamma-carboxyglutamate protein 3
chr11_-_58534825 0.53 ENSMUST00000170009.1
olfactory receptor 330
chr2_-_167062981 0.53 ENSMUST00000048988.7
zinc finger, NFX1-type containing 1
chr17_+_36042956 0.52 ENSMUST00000097331.1
predicted gene 6034
chr11_-_109298066 0.52 ENSMUST00000106706.1
regulator of G-protein signaling 9
chr7_+_78913436 0.52 ENSMUST00000121645.1
interferon-stimulated protein
chr10_-_75797528 0.52 ENSMUST00000120177.1
glutathione S-transferase, theta 1
chr14_+_103513328 0.51 ENSMUST00000095576.3
sciellin
chr11_-_3931789 0.51 ENSMUST00000109992.1
ENSMUST00000109988.1
transcobalamin 2
chr11_+_49087022 0.51 ENSMUST00000046704.6
interferon gamma inducible protein 47
chr3_+_127791374 0.51 ENSMUST00000171621.1
TRAF-interacting protein with forkhead-associated domain
chr5_-_105139539 0.51 ENSMUST00000100961.4
ENSMUST00000031235.6
ENSMUST00000100962.3
guanylate-binding protein 9
guanylate-binding protein 8
guanylate binding protein 4
chr17_-_31144271 0.51 ENSMUST00000024826.7
trefoil factor 2 (spasmolytic protein 1)
chr2_+_104095796 0.51 ENSMUST00000040423.5
ENSMUST00000168176.1
CD59a antigen
chr11_-_61267177 0.51 ENSMUST00000066277.3
ENSMUST00000074127.7
ENSMUST00000108715.2
aldehyde dehydrogenase family 3, subfamily A2
chr6_+_139843648 0.50 ENSMUST00000087657.6
phosphatidylinositol 3-kinase, C2 domain containing, gamma polypeptide
chr1_+_58802492 0.50 ENSMUST00000165549.1
caspase 8
chrX_-_134161928 0.50 ENSMUST00000033611.4
X Kell blood group precursor related X linked
chr5_-_116024475 0.50 ENSMUST00000111999.1
protein kinase, AMP-activated, beta 1 non-catalytic subunit

Network of associatons between targets according to the STRING database.

First level regulatory network of Irf2_Irf1_Irf8_Irf9_Irf7

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 6.5 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
1.5 1.5 GO:0002589 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589)
1.0 3.8 GO:1901740 negative regulation of myoblast fusion(GO:1901740)
0.9 2.6 GO:1902524 positive regulation of protein K48-linked ubiquitination(GO:1902524)
0.8 5.0 GO:0035546 interferon-beta secretion(GO:0035546) regulation of interferon-beta secretion(GO:0035547) positive regulation of interferon-beta secretion(GO:0035549)
0.8 2.3 GO:0042196 dichloromethane metabolic process(GO:0018900) chlorinated hydrocarbon metabolic process(GO:0042196) halogenated hydrocarbon metabolic process(GO:0042197)
0.8 1.5 GO:0034165 positive regulation of toll-like receptor 9 signaling pathway(GO:0034165)
0.8 3.8 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.7 2.2 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.6 1.9 GO:0006227 dUDP biosynthetic process(GO:0006227) pyrimidine nucleoside diphosphate metabolic process(GO:0009138) pyrimidine nucleoside diphosphate biosynthetic process(GO:0009139) pyrimidine deoxyribonucleoside diphosphate metabolic process(GO:0009196) pyrimidine deoxyribonucleoside diphosphate biosynthetic process(GO:0009197) dUDP metabolic process(GO:0046077)
0.5 2.2 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.5 2.5 GO:1904720 regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.5 5.5 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.4 17.0 GO:0042832 defense response to protozoan(GO:0042832)
0.4 0.4 GO:0002477 antigen processing and presentation of exogenous peptide antigen via MHC class Ib(GO:0002477) antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent(GO:0002481)
0.4 1.7 GO:0044565 dendritic cell proliferation(GO:0044565)
0.4 1.2 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.4 1.8 GO:0034239 regulation of macrophage fusion(GO:0034239)
0.3 1.3 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.3 0.9 GO:0070947 neutrophil mediated killing of fungus(GO:0070947)
0.3 0.6 GO:0045404 positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.3 2.1 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.3 0.8 GO:0002014 vasoconstriction of artery involved in ischemic response to lowering of systemic arterial blood pressure(GO:0002014)
0.3 2.1 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.3 3.7 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.3 1.3 GO:0034124 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124)
0.3 1.5 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.2 1.6 GO:0002606 positive regulation of dendritic cell antigen processing and presentation(GO:0002606)
0.2 1.4 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.2 0.2 GO:1990009 retinal cell apoptotic process(GO:1990009)
0.2 1.3 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.2 1.9 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.2 0.9 GO:1904124 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.2 2.7 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.2 1.2 GO:0003383 apical constriction(GO:0003383)
0.2 0.8 GO:1903896 positive regulation of IRE1-mediated unfolded protein response(GO:1903896)
0.2 0.8 GO:0001692 histamine metabolic process(GO:0001692)
0.2 1.3 GO:0090086 negative regulation of protein deubiquitination(GO:0090086)
0.2 0.5 GO:0034769 basement membrane disassembly(GO:0034769)
0.2 0.4 GO:0045351 type I interferon biosynthetic process(GO:0045351)
0.2 0.4 GO:0060300 regulation of cytokine activity(GO:0060300)
0.2 0.5 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.2 1.1 GO:0018377 protein myristoylation(GO:0018377)
0.2 0.5 GO:0031296 B cell costimulation(GO:0031296)
0.1 0.4 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.1 0.7 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.1 0.4 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.1 0.3 GO:0039533 regulation of MDA-5 signaling pathway(GO:0039533)
0.1 0.6 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.1 0.7 GO:0001969 activation of membrane attack complex(GO:0001905) regulation of activation of membrane attack complex(GO:0001969)
0.1 2.0 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 0.1 GO:0045626 negative regulation of T-helper 1 cell differentiation(GO:0045626)
0.1 0.4 GO:0046351 disaccharide biosynthetic process(GO:0046351)
0.1 0.4 GO:2000642 negative regulation of early endosome to late endosome transport(GO:2000642)
0.1 0.4 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990) cellular response to fructose stimulus(GO:0071332)
0.1 2.5 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.1 0.5 GO:1902896 terminal web assembly(GO:1902896)
0.1 0.5 GO:0016332 establishment or maintenance of polarity of embryonic epithelium(GO:0016332)
0.1 0.5 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.1 0.4 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.1 0.4 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.1 0.5 GO:0015889 cobalamin transport(GO:0015889)
0.1 1.1 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.1 0.3 GO:0019085 early viral transcription(GO:0019085)
0.1 0.6 GO:0010940 positive regulation of necrotic cell death(GO:0010940)
0.1 0.4 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.1 0.3 GO:0002730 regulation of dendritic cell cytokine production(GO:0002730)
0.1 0.3 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.1 0.7 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.1 0.3 GO:0048239 negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695)
0.1 0.4 GO:0009992 cellular water homeostasis(GO:0009992)
0.1 0.3 GO:0071211 protein targeting to vacuole involved in autophagy(GO:0071211)
0.1 0.8 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.1 0.7 GO:0046292 formaldehyde metabolic process(GO:0046292)
0.1 0.3 GO:1904933 regulation of cell proliferation in midbrain(GO:1904933)
0.1 0.3 GO:0007161 substrate-dependent cell migration, cell attachment to substrate(GO:0006931) calcium-independent cell-matrix adhesion(GO:0007161)
0.1 0.8 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 0.3 GO:1900020 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.1 0.4 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.1 1.2 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.1 0.4 GO:0048496 maintenance of organ identity(GO:0048496)
0.1 0.3 GO:2000338 positive regulation of interleukin-23 production(GO:0032747) chemokine (C-X-C motif) ligand 1 production(GO:0072566) regulation of chemokine (C-X-C motif) ligand 1 production(GO:2000338)
0.1 0.3 GO:0090126 protein complex assembly involved in synapse maturation(GO:0090126)
0.1 0.5 GO:0060455 negative regulation of gastric acid secretion(GO:0060455)
0.1 0.9 GO:0003374 dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374)
0.1 0.6 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.1 2.3 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.1 0.3 GO:0046098 guanine metabolic process(GO:0046098)
0.1 0.5 GO:1903207 neuron death in response to hydrogen peroxide(GO:0036476) regulation of hydrogen peroxide-induced neuron death(GO:1903207) negative regulation of hydrogen peroxide-induced neuron death(GO:1903208)
0.1 1.0 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.1 0.4 GO:0015692 vanadium ion transport(GO:0015676) lead ion transport(GO:0015692)
0.1 0.5 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.1 0.2 GO:0072733 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.1 0.4 GO:0097106 postsynaptic density organization(GO:0097106)
0.1 0.3 GO:0006680 glucosylceramide catabolic process(GO:0006680)
0.1 0.3 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.1 0.7 GO:0035878 nail development(GO:0035878)
0.1 1.6 GO:0044458 motile cilium assembly(GO:0044458)
0.1 0.4 GO:0007258 JUN phosphorylation(GO:0007258)
0.1 0.6 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.1 0.1 GO:1902938 regulation of intracellular calcium activated chloride channel activity(GO:1902938)
0.1 0.7 GO:0071763 nuclear membrane organization(GO:0071763)
0.1 0.4 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.1 0.5 GO:1990504 dense core granule exocytosis(GO:1990504)
0.1 0.9 GO:0071360 cellular response to exogenous dsRNA(GO:0071360)
0.1 0.1 GO:0018307 enzyme active site formation(GO:0018307)
0.1 1.5 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.1 0.2 GO:0061518 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518)
0.1 1.4 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 0.3 GO:0038094 Fc-gamma receptor signaling pathway(GO:0038094)
0.1 0.4 GO:0044375 regulation of peroxisome size(GO:0044375)
0.1 1.0 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.1 0.8 GO:0035455 response to interferon-alpha(GO:0035455)
0.1 0.2 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.1 0.8 GO:0060330 regulation of response to interferon-gamma(GO:0060330)
0.1 0.4 GO:1900227 positive regulation of NLRP3 inflammasome complex assembly(GO:1900227)
0.1 0.4 GO:0031642 negative regulation of myelination(GO:0031642)
0.1 0.4 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.1 0.3 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.1 9.4 GO:0016052 carbohydrate catabolic process(GO:0016052)
0.1 0.2 GO:0009814 defense response, incompatible interaction(GO:0009814) defense response to bacterium, incompatible interaction(GO:0009816) regulation of defense response to bacterium, incompatible interaction(GO:1902477)
0.1 1.0 GO:0030238 male sex determination(GO:0030238)
0.1 0.3 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.1 0.2 GO:1905204 negative regulation of connective tissue replacement(GO:1905204)
0.1 0.7 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 8.5 GO:0051607 defense response to virus(GO:0051607)
0.1 0.4 GO:0019348 dolichol metabolic process(GO:0019348)
0.1 2.8 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.0 0.1 GO:0070459 prolactin secretion(GO:0070459)
0.0 0.8 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.1 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.1 GO:0006583 melanin biosynthetic process from tyrosine(GO:0006583)
0.0 0.1 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
0.0 0.3 GO:0032439 endosome localization(GO:0032439)
0.0 0.1 GO:1901026 ripoptosome assembly(GO:0097343) ripoptosome assembly involved in necroptotic process(GO:1901026)
0.0 0.3 GO:0008300 isoprenoid catabolic process(GO:0008300)
0.0 0.8 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.4 GO:0044336 canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
0.0 0.2 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.3 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.0 0.1 GO:0006011 UDP-glucose metabolic process(GO:0006011)
0.0 1.0 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.0 0.1 GO:0002370 natural killer cell cytokine production(GO:0002370) regulation of natural killer cell cytokine production(GO:0002727)
0.0 0.7 GO:0070266 necroptotic process(GO:0070266)
0.0 0.2 GO:0032074 negative regulation of nuclease activity(GO:0032074)
0.0 0.3 GO:0034242 negative regulation of syncytium formation by plasma membrane fusion(GO:0034242)
0.0 0.2 GO:0039019 pronephric nephron development(GO:0039019)
0.0 0.2 GO:0019532 oxalate transport(GO:0019532)
0.0 0.4 GO:0007343 egg activation(GO:0007343)
0.0 0.1 GO:0070425 regulation of granuloma formation(GO:0002631) negative regulation of granuloma formation(GO:0002632) regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070425) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070433) tolerance induction to lipopolysaccharide(GO:0072573)
0.0 0.0 GO:2000562 negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.0 0.4 GO:0031000 response to caffeine(GO:0031000)
0.0 0.2 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.0 0.2 GO:0035608 protein deglutamylation(GO:0035608) protein side chain deglutamylation(GO:0035610)
0.0 0.4 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.4 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.0 0.4 GO:0034626 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.1 GO:0061743 motor learning(GO:0061743)
0.0 1.0 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.0 0.2 GO:1902856 negative regulation of nonmotile primary cilium assembly(GO:1902856)
0.0 0.8 GO:0061462 protein localization to lysosome(GO:0061462)
0.0 0.4 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.0 1.4 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.0 0.1 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.4 GO:0031953 negative regulation of protein autophosphorylation(GO:0031953)
0.0 0.1 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.0 0.2 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.0 0.2 GO:0042758 long-chain fatty acid catabolic process(GO:0042758)
0.0 0.2 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.4 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.3 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.0 0.3 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.1 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.3 GO:0042126 nitrate metabolic process(GO:0042126)
0.0 0.1 GO:0051204 protein insertion into mitochondrial membrane(GO:0051204)
0.0 1.2 GO:0070306 lens fiber cell differentiation(GO:0070306)
0.0 0.1 GO:0060809 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302) mesodermal to mesenchymal transition involved in gastrulation(GO:0060809)
0.0 0.3 GO:0010529 regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529)
0.0 0.3 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.3 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.1 GO:0060664 epithelial cell proliferation involved in salivary gland morphogenesis(GO:0060664)
0.0 0.1 GO:0060022 hard palate development(GO:0060022)
0.0 0.2 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.0 0.1 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.0 0.1 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.0 0.1 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.0 0.3 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.0 0.1 GO:0051342 regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.0 0.1 GO:0060744 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.0 0.1 GO:1904959 regulation of electron carrier activity(GO:1904732) regulation of cytochrome-c oxidase activity(GO:1904959)
0.0 0.2 GO:0006983 ER overload response(GO:0006983)
0.0 0.5 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 1.6 GO:0009166 nucleotide catabolic process(GO:0009166)
0.0 0.0 GO:0061428 negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.0 0.2 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.1 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.0 0.1 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.0 0.7 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.3 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.0 0.2 GO:1904220 regulation of serine C-palmitoyltransferase activity(GO:1904220)
0.0 0.3 GO:1990118 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.7 GO:0010107 potassium ion import(GO:0010107)
0.0 0.1 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.0 0.1 GO:1905051 regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053)
0.0 0.2 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.1 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.0 0.3 GO:0051601 exocyst localization(GO:0051601)
0.0 1.0 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 0.7 GO:0051642 centrosome localization(GO:0051642)
0.0 0.2 GO:1904424 regulation of GTP binding(GO:1904424)
0.0 0.1 GO:0036414 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.0 0.3 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.1 GO:0070460 thyroid-stimulating hormone secretion(GO:0070460)
0.0 0.0 GO:0009730 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.0 0.3 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0 0.3 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.1 GO:0031937 positive regulation of chromatin silencing(GO:0031937)
0.0 0.1 GO:0002154 thyroid hormone mediated signaling pathway(GO:0002154) regulation of thyroid hormone mediated signaling pathway(GO:0002155)
0.0 0.6 GO:0045823 positive regulation of heart contraction(GO:0045823)
0.0 2.4 GO:0007601 visual perception(GO:0007601)
0.0 0.1 GO:0045836 positive regulation of meiotic nuclear division(GO:0045836)
0.0 0.0 GO:0006624 vacuolar protein processing(GO:0006624)
0.0 0.1 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.1 GO:0070495 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.0 0.1 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.3 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.0 0.2 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.0 GO:2000821 regulation of grooming behavior(GO:2000821)
0.0 0.5 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.4 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.5 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.0 GO:1904569 regulation of selenocysteine incorporation(GO:1904569)
0.0 0.2 GO:0098543 detection of bacterium(GO:0016045) detection of other organism(GO:0098543)
0.0 0.1 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.6 GO:0009250 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 0.2 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.0 0.9 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.0 0.0 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.1 GO:0098795 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.0 0.1 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.0 0.1 GO:0021678 third ventricle development(GO:0021678)
0.0 0.3 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.1 GO:0060923 cardiac muscle cell fate commitment(GO:0060923)
0.0 0.3 GO:0036344 platelet formation(GO:0030220) platelet morphogenesis(GO:0036344)
0.0 0.2 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.1 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 0.3 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.0 0.1 GO:0035902 response to immobilization stress(GO:0035902)
0.0 0.2 GO:0035067 negative regulation of histone acetylation(GO:0035067)
0.0 0.1 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.3 GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.0 0.1 GO:0032836 glomerular basement membrane development(GO:0032836)
0.0 0.6 GO:0035019 somatic stem cell population maintenance(GO:0035019)
0.0 0.0 GO:0001712 ectodermal cell fate commitment(GO:0001712)
0.0 0.0 GO:1904109 positive regulation of intracellular lipid transport(GO:0032379) positive regulation of intracellular sterol transport(GO:0032382) positive regulation of intracellular cholesterol transport(GO:0032385) lipid hydroperoxide transport(GO:1901373) positive regulation of cholesterol import(GO:1904109) positive regulation of sterol import(GO:2000911)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 4.2 GO:1990111 spermatoproteasome complex(GO:1990111)
0.8 11.1 GO:0020003 symbiont-containing vacuole(GO:0020003)
0.4 3.0 GO:0042825 TAP complex(GO:0042825)
0.3 1.2 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.3 3.3 GO:0042612 MHC class I protein complex(GO:0042612)
0.2 1.4 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.2 1.6 GO:1990462 omegasome(GO:1990462)
0.2 1.7 GO:0045098 type III intermediate filament(GO:0045098)
0.2 1.8 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.2 1.3 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.2 1.2 GO:0033269 internode region of axon(GO:0033269)
0.1 1.1 GO:1990357 terminal web(GO:1990357)
0.1 2.1 GO:0044754 autolysosome(GO:0044754)
0.1 0.4 GO:0042584 chromaffin granule membrane(GO:0042584)
0.1 2.0 GO:0043186 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.1 0.4 GO:1990696 USH2 complex(GO:1990696)
0.1 0.4 GO:0097447 dendritic tree(GO:0097447)
0.1 0.5 GO:1990037 Lewy body core(GO:1990037)
0.1 0.7 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 0.4 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.1 0.3 GO:0032127 dense core granule membrane(GO:0032127)
0.1 0.6 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.1 0.8 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.1 0.4 GO:0070826 paraferritin complex(GO:0070826)
0.1 0.3 GO:0043202 lysosomal lumen(GO:0043202)
0.1 1.5 GO:0043196 varicosity(GO:0043196)
0.1 0.4 GO:0071986 Ragulator complex(GO:0071986)
0.1 0.4 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.1 0.2 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.1 0.7 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.1 0.7 GO:0042611 MHC protein complex(GO:0042611)
0.1 2.2 GO:0055038 recycling endosome membrane(GO:0055038)
0.1 1.3 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.1 1.3 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 0.3 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.2 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.0 0.5 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0 2.4 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.7 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.4 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.3 GO:0005787 signal peptidase complex(GO:0005787)
0.0 5.3 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.0 0.4 GO:0001533 cornified envelope(GO:0001533)
0.0 0.1 GO:0000814 ESCRT II complex(GO:0000814)
0.0 0.4 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.3 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.3 GO:0042587 glycogen granule(GO:0042587)
0.0 0.1 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 3.8 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.5 GO:0000124 SAGA complex(GO:0000124)
0.0 0.2 GO:0072557 IPAF inflammasome complex(GO:0072557)
0.0 1.4 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 4.9 GO:0005923 bicellular tight junction(GO:0005923)
0.0 0.9 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.5 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.3 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 1.3 GO:0015030 Cajal body(GO:0015030)
0.0 0.4 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.3 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.3 GO:0097542 ciliary tip(GO:0097542)
0.0 0.8 GO:0005921 gap junction(GO:0005921)
0.0 0.2 GO:0070695 FHF complex(GO:0070695)
0.0 0.2 GO:0031105 septin complex(GO:0031105)
0.0 1.4 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.2 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.8 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.5 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 1.1 GO:0001772 immunological synapse(GO:0001772)
0.0 0.1 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.0 0.2 GO:0045179 apical cortex(GO:0045179)
0.0 0.4 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.1 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.1 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.1 GO:0097441 basilar dendrite(GO:0097441)
0.0 1.5 GO:0005811 lipid particle(GO:0005811)
0.0 0.1 GO:0002177 manchette(GO:0002177)
0.0 0.4 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.0 0.4 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.7 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.1 GO:0044307 dendritic branch(GO:0044307)
0.0 0.6 GO:0009925 basal plasma membrane(GO:0009925)
0.0 1.4 GO:0036126 sperm flagellum(GO:0036126)
0.0 1.4 GO:0005604 basement membrane(GO:0005604)
0.0 0.1 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.8 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 8.7 GO:0004556 alpha-amylase activity(GO:0004556)
0.9 3.8 GO:0008859 exoribonuclease II activity(GO:0008859)
0.8 2.3 GO:0019120 hydrolase activity, acting on acid halide bonds(GO:0016824) hydrolase activity, acting on acid halide bonds, in C-halide compounds(GO:0019120) alkylhalidase activity(GO:0047651)
0.6 1.9 GO:0009041 uridylate kinase activity(GO:0009041)
0.6 2.9 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.5 4.9 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.4 3.0 GO:0046978 TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
0.4 2.5 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.3 1.7 GO:0004850 uridine phosphorylase activity(GO:0004850)
0.3 1.3 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.3 1.0 GO:0005118 sevenless binding(GO:0005118)
0.3 4.1 GO:0050700 CARD domain binding(GO:0050700)
0.3 1.3 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.2 1.2 GO:0031849 olfactory receptor binding(GO:0031849)
0.2 2.1 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.2 1.5 GO:0032027 myosin light chain binding(GO:0032027)
0.2 0.6 GO:0004967 glucagon receptor activity(GO:0004967)
0.2 1.6 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.2 0.5 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.2 0.7 GO:0070976 TIR domain binding(GO:0070976)
0.2 1.7 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.2 1.9 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.2 0.6 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733)
0.1 0.1 GO:1903135 cupric ion binding(GO:1903135)
0.1 0.4 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.1 1.6 GO:0038187 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.1 0.5 GO:0008147 structural constituent of bone(GO:0008147)
0.1 2.9 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.1 2.0 GO:0042605 peptide antigen binding(GO:0042605)
0.1 0.5 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.1 0.3 GO:0070401 NADP+ binding(GO:0070401)
0.1 0.4 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 0.4 GO:0003844 1,4-alpha-glucan branching enzyme activity(GO:0003844)
0.1 0.8 GO:0015288 porin activity(GO:0015288)
0.1 0.4 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.1 0.9 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 0.3 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.1 0.3 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.1 8.0 GO:0003725 double-stranded RNA binding(GO:0003725)
0.1 0.4 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.1 2.3 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 0.3 GO:0034584 piRNA binding(GO:0034584)
0.1 0.3 GO:0098809 nitrite reductase activity(GO:0098809)
0.1 0.7 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 0.4 GO:0015639 cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.1 0.3 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.1 1.8 GO:0045295 gamma-catenin binding(GO:0045295)
0.1 0.2 GO:0008176 tRNA (guanine-N7-)-methyltransferase activity(GO:0008176)
0.1 0.2 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.1 0.2 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.1 0.4 GO:0045340 mercury ion binding(GO:0045340)
0.1 1.6 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 0.2 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
0.1 0.4 GO:0042296 ISG15 transferase activity(GO:0042296)
0.1 1.2 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 0.7 GO:0043495 protein anchor(GO:0043495)
0.1 1.4 GO:0005521 lamin binding(GO:0005521)
0.1 0.5 GO:0031419 cobalamin binding(GO:0031419)
0.1 0.8 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 0.4 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.1 0.3 GO:0089720 caspase binding(GO:0089720)
0.1 0.2 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.1 2.1 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.2 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.0 0.2 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.0 0.4 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.0 0.1 GO:0004658 propionyl-CoA carboxylase activity(GO:0004658)
0.0 0.2 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.0 0.3 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.7 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.6 GO:0050308 sugar-phosphatase activity(GO:0050308)
0.0 2.4 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.3 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 1.1 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.2 GO:0005093 Rab GDP-dissociation inhibitor activity(GO:0005093)
0.0 0.7 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.2 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.3 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 0.2 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.0 0.3 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.4 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.3 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.5 GO:0031386 protein tag(GO:0031386)
0.0 0.1 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.1 GO:0031531 thyrotropin-releasing hormone receptor binding(GO:0031531)
0.0 0.2 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.5 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 1.9 GO:0016836 hydro-lyase activity(GO:0016836)
0.0 1.1 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.2 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.0 0.3 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.8 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.1 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.0 0.1 GO:0032129 histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969)
0.0 9.4 GO:0003924 GTPase activity(GO:0003924)
0.0 1.3 GO:0043531 ADP binding(GO:0043531)
0.0 5.1 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.3 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.1 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.1 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.0 0.1 GO:0036004 GAF domain binding(GO:0036004)
0.0 2.0 GO:0019843 rRNA binding(GO:0019843)
0.0 0.7 GO:0001848 complement binding(GO:0001848)
0.0 0.3 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.3 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 1.5 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.3 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
0.0 1.0 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.1 GO:1902379 chemoattractant activity involved in axon guidance(GO:1902379)
0.0 0.7 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.1 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.0 0.3 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 0.2 GO:0004396 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.2 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.8 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.1 GO:0008494 translation activator activity(GO:0008494)
0.0 0.0 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.0 0.1 GO:0035174 histone serine kinase activity(GO:0035174)
0.0 0.1 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.1 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0 0.3 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.1 GO:1903136 cuprous ion binding(GO:1903136)
0.0 0.2 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.1 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.4 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.1 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.1 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
0.0 0.2 GO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor(GO:0016624)
0.0 0.8 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.1 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.0 0.2 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.2 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.7 GO:0050699 WW domain binding(GO:0050699)
0.0 1.7 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.2 GO:0051400 BH domain binding(GO:0051400)
0.0 0.1 GO:0050897 cobalt ion binding(GO:0050897)
0.0 0.3 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.1 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.5 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.8 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.1 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.2 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.2 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.1 GO:0034711 inhibin binding(GO:0034711)
0.0 1.5 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.2 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.1 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.1 GO:0004661 protein geranylgeranyltransferase activity(GO:0004661)
0.0 0.4 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.2 GO:0046527 glucosyltransferase activity(GO:0046527)
0.0 0.0 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.1 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0 0.1 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.0 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.0 GO:0050632 propanoyl-CoA C-acyltransferase activity(GO:0033814) propionyl-CoA C2-trimethyltridecanoyltransferase activity(GO:0050632) phosphatidylethanolamine transporter activity(GO:1904121)
0.0 0.1 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.0 0.2 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.0 1.5 GO:0047485 protein N-terminus binding(GO:0047485)
0.0 0.3 GO:0005112 Notch binding(GO:0005112)
0.0 0.1 GO:0005536 glucose binding(GO:0005536)
0.0 0.0 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0 0.1 GO:0016936 galactoside binding(GO:0016936)
0.0 0.4 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.0 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.1 0.1 PID GLYPICAN 1PATHWAY Glypican 1 network
0.1 2.9 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 1.2 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 1.6 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 1.7 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 6.4 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 0.9 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.1 0.8 PID TRAIL PATHWAY TRAIL signaling pathway
0.1 2.0 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 0.9 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.1 1.4 PID CONE PATHWAY Visual signal transduction: Cones
0.0 2.8 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 1.1 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.5 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 1.0 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.3 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.9 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 1.2 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.3 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.6 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 1.9 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.3 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 1.6 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 0.8 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 0.4 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 2.1 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 1.4 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.4 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.7 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.7 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.6 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.6 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.4 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.6 PID AURORA A PATHWAY Aurora A signaling
0.0 0.2 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.1 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.3 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 0.1 PID IGF1 PATHWAY IGF1 pathway
0.0 0.2 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.6 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.4 PID FGF PATHWAY FGF signaling pathway
0.0 0.5 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.5 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 2.6 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.3 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.1 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.9 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.3 5.6 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.3 14.5 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.2 2.4 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.2 1.6 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.2 2.3 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.2 2.2 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.2 2.1 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 1.0 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 1.8 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.1 3.3 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.1 2.2 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1 2.0 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 1.1 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.1 0.5 REACTOME DEFENSINS Genes involved in Defensins
0.1 1.2 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 1.0 REACTOME RIG I MDA5 MEDIATED INDUCTION OF IFN ALPHA BETA PATHWAYS Genes involved in RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
0.1 0.8 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.1 2.5 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 0.3 REACTOME P75NTR SIGNALS VIA NFKB Genes involved in p75NTR signals via NF-kB
0.1 1.3 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.1 0.4 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.3 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.0 0.4 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.2 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
0.0 1.3 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.7 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 1.5 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 1.2 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 1.2 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.7 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.4 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.8 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.5 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 0.5 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.5 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 1.1 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.3 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 1.2 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.0 0.3 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.6 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.2 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.2 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.3 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.3 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.6 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.1 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 1.1 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.0 0.2 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.5 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.3 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0 1.5 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.0 0.2 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.3 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.3 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.1 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.3 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.5 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.3 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.4 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.2 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.2 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.2 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.0 REACTOME MRNA PROCESSING Genes involved in mRNA Processing