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12D miR HR13_24

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Results for Rxrb

Z-value: 1.17

Motif logo

Transcription factors associated with Rxrb

Gene Symbol Gene ID Gene Info
ENSMUSG00000039656.10 retinoid X receptor beta

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Rxrbmm10_v2_chr17_+_34032348_340324010.933.6e-05Click!

Activity profile of Rxrb motif

Sorted Z-values of Rxrb motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_40733373 3.08 ENSMUST00000020579.8
hyaluronan mediated motility receptor (RHAMM)
chr16_-_44333135 2.90 ENSMUST00000047446.6
SID1 transmembrane family, member 1
chr16_-_44332925 2.86 ENSMUST00000136381.1
SID1 transmembrane family, member 1
chr15_-_101562889 2.26 ENSMUST00000023714.4
RIKEN cDNA 4732456N10 gene
chr12_+_91400990 2.17 ENSMUST00000021346.7
ENSMUST00000021343.6
thyroid stimulating hormone receptor
chr4_-_117178726 2.11 ENSMUST00000153953.1
ENSMUST00000106436.1
kinesin family member 2C
chr11_+_79660532 2.04 ENSMUST00000155381.1
RAB11 family interacting protein 4 (class II)
chr4_+_44300876 2.02 ENSMUST00000045607.5
maternal embryonic leucine zipper kinase
chr10_-_88146867 2.00 ENSMUST00000164121.1
ENSMUST00000164803.1
ENSMUST00000168163.1
ENSMUST00000048518.9
PARP1 binding protein
chr14_+_54476100 1.96 ENSMUST00000164766.1
ENSMUST00000164697.1
rad and gem related GTP binding protein 2
chr15_-_79285502 1.89 ENSMUST00000165408.1
BAI1-associated protein 2-like 2
chr15_+_78430086 1.85 ENSMUST00000162808.1
potassium channel tetramerisation domain containing 17
chr5_-_134747241 1.85 ENSMUST00000015138.9
elastin
chr7_-_4778141 1.74 ENSMUST00000094892.5
interleukin 11
chr5_+_110839973 1.72 ENSMUST00000066160.1
checkpoint kinase 2
chr7_-_141434532 1.41 ENSMUST00000133021.1
ENSMUST00000106007.3
ENSMUST00000150026.1
ENSMUST00000133206.2
solute carrier family 25 (mitochondrial carrier, glutamate), member 22
chr6_+_113531675 1.33 ENSMUST00000036340.5
ENSMUST00000101051.2
Fanconi anemia, complementation group D2
chr7_-_141434402 1.33 ENSMUST00000136354.1
solute carrier family 25 (mitochondrial carrier, glutamate), member 22
chr6_+_119236507 1.26 ENSMUST00000037434.6
calcium channel, voltage-dependent, alpha 2/delta subunit 4
chr13_-_28953690 1.25 ENSMUST00000067230.5
SRY-box containing gene 4
chr2_-_136387929 1.14 ENSMUST00000035264.2
ENSMUST00000077200.3
p21 protein (Cdc42/Rac)-activated kinase 7
chr17_-_32388885 1.06 ENSMUST00000087703.5
ENSMUST00000170603.1
widely-interspaced zinc finger motifs
chr13_+_44729794 0.98 ENSMUST00000172830.1
jumonji, AT rich interactive domain 2
chr11_-_3722189 0.88 ENSMUST00000102950.3
ENSMUST00000101632.3
oxysterol binding protein 2
chr2_-_80128834 0.88 ENSMUST00000102654.4
ENSMUST00000102655.3
phosphodiesterase 1A, calmodulin-dependent
chr11_-_97629685 0.87 ENSMUST00000052281.4
RIKEN cDNA E130012A19 gene
chr17_+_48264270 0.87 ENSMUST00000059873.7
ENSMUST00000154335.1
ENSMUST00000136272.1
ENSMUST00000125426.1
ENSMUST00000153420.1
triggering receptor expressed on myeloid cells-like 4
chr11_+_40733936 0.86 ENSMUST00000127382.1
NudC domain containing 2
chr11_-_68973840 0.86 ENSMUST00000038644.4
RAN guanine nucleotide release factor
chr11_+_40733639 0.85 ENSMUST00000020578.4
NudC domain containing 2
chr15_-_5244178 0.83 ENSMUST00000047379.8
prostaglandin E receptor 4 (subtype EP4)
chr19_+_11770415 0.83 ENSMUST00000167199.1
mitochondrial ribosomal protein L16
chr2_+_154548888 0.81 ENSMUST00000045116.4
ENSMUST00000109709.3
RIKEN cDNA 1700003F12 gene
chr15_-_5244164 0.79 ENSMUST00000120563.1
prostaglandin E receptor 4 (subtype EP4)
chr12_-_98737405 0.78 ENSMUST00000170188.1
protein tyrosine phosphatase, non-receptor type 21
chr15_+_101447745 0.77 ENSMUST00000023781.7
RIKEN cDNA 1700011A15 gene
chr1_-_9631092 0.77 ENSMUST00000115480.1
RIKEN cDNA 2610203C22 gene
chr4_+_130047840 0.76 ENSMUST00000044565.8
ENSMUST00000132251.1
collagen, type XVI, alpha 1
chr5_-_110839757 0.70 ENSMUST00000056937.5
HscB iron-sulfur cluster co-chaperone homolog (E. coli)
chr14_-_55106547 0.68 ENSMUST00000036041.8
adaptor protein complex AP-1, gamma 2 subunit
chr1_-_180193653 0.65 ENSMUST00000159914.1
aarF domain containing kinase 3
chr5_+_108065696 0.58 ENSMUST00000172045.1
metal response element binding transcription factor 2
chr18_+_60774675 0.58 ENSMUST00000118551.1
ribosomal protein S14
chr6_-_124863877 0.58 ENSMUST00000046893.7
G protein-coupled receptor 162
chr16_-_30388530 0.57 ENSMUST00000100013.2
ENSMUST00000061350.6
ATPase type 13A3
chr1_-_170306332 0.56 ENSMUST00000179801.1
predicted gene 7694
chr18_+_60774510 0.56 ENSMUST00000025511.3
ribosomal protein S14
chr7_-_142095266 0.55 ENSMUST00000039926.3
dual specificity phosphatase 8
chr15_+_92161343 0.54 ENSMUST00000068378.5
contactin 1
chr2_-_73911323 0.53 ENSMUST00000111996.1
ENSMUST00000018914.2
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C3 (subunit 9)
chr7_+_35802593 0.53 ENSMUST00000052454.2
RIKEN cDNA E130304I02 gene
chr12_+_33314277 0.52 ENSMUST00000133549.1
ataxin 7-like 1
chr1_+_74791516 0.51 ENSMUST00000006718.8
wingless related MMTV integration site 10a
chr2_-_119662756 0.51 ENSMUST00000028768.1
ENSMUST00000110801.1
ENSMUST00000110802.1
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 1
chr11_-_53430779 0.49 ENSMUST00000061326.4
ENSMUST00000109021.3
ubiquinol-cytochrome c reductase, complex III subunit VII
chr10_+_61720592 0.48 ENSMUST00000080099.5
apoptosis-inducing factor, mitochondrion-associated 2
chr11_-_95699143 0.47 ENSMUST00000062249.2
predicted gene 9796
chr14_+_20929416 0.47 ENSMUST00000022369.7
vinculin
chr8_+_105708270 0.46 ENSMUST00000013302.5
RIKEN cDNA 4933405L10 gene
chr17_-_17855188 0.45 ENSMUST00000003762.6
hyaluronan synthase1
chr10_+_88147061 0.45 ENSMUST00000169309.1
nucleoporin 37
chr1_+_6487231 0.45 ENSMUST00000140079.1
ENSMUST00000131494.1
suppression of tumorigenicity 18
chr12_-_111712946 0.44 ENSMUST00000160825.1
ENSMUST00000162953.1
BCL2-associated athanogene 5
chr1_-_140183404 0.44 ENSMUST00000066859.6
ENSMUST00000111976.2
complement component factor h
chr10_+_88146992 0.42 ENSMUST00000052355.7
nucleoporin 37
chr11_-_106973090 0.42 ENSMUST00000150366.1
predicted gene 11707
chr4_+_130047914 0.41 ENSMUST00000142293.1
collagen, type XVI, alpha 1
chr6_-_83054415 0.41 ENSMUST00000113962.1
ENSMUST00000089645.6
ENSMUST00000113963.1
HtrA serine peptidase 2
chr2_+_118900377 0.40 ENSMUST00000151162.1
bromo adjacent homology domain containing 1
chr11_-_29547820 0.39 ENSMUST00000102844.3
ribosomal protein S27A
chr1_-_140183283 0.38 ENSMUST00000111977.1
complement component factor h
chr6_-_124965248 0.38 ENSMUST00000129976.1
COP9 (constitutive photomorphogenic) homolog, subunit 7a (Arabidopsis thaliana)
chr2_-_80129458 0.38 ENSMUST00000102653.1
phosphodiesterase 1A, calmodulin-dependent
chr6_-_124965485 0.38 ENSMUST00000112439.2
COP9 (constitutive photomorphogenic) homolog, subunit 7a (Arabidopsis thaliana)
chr5_-_110839575 0.38 ENSMUST00000145318.1
HscB iron-sulfur cluster co-chaperone homolog (E. coli)
chr4_-_62360524 0.36 ENSMUST00000107461.1
ENSMUST00000084528.3
FK506 binding protein 15
chr9_-_50659780 0.35 ENSMUST00000034567.3
dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex)
chr11_+_29547950 0.35 ENSMUST00000020753.3
clathrin heavy chain linker domain containing 1
chr4_+_136143497 0.35 ENSMUST00000008016.2
inhibitor of DNA binding 3
chr13_+_55209776 0.33 ENSMUST00000099490.2
nuclear receptor-binding SET-domain protein 1
chr6_-_129533267 0.33 ENSMUST00000181594.1
RIKEN cDNA 1700101I11 gene
chr10_+_80148263 0.33 ENSMUST00000099492.3
ENSMUST00000042057.5
midnolin
chr8_-_70792392 0.33 ENSMUST00000166004.1
microtubule associated serine/threonine kinase 3
chr5_-_123666682 0.32 ENSMUST00000149410.1
CAP-GLY domain containing linker protein 1
chrX_-_23365044 0.31 ENSMUST00000115313.1
kelch-like 13
chr13_-_54688246 0.28 ENSMUST00000122935.1
ENSMUST00000128257.1
ring finger protein 44
chr2_-_119477613 0.27 ENSMUST00000110808.1
ENSMUST00000049920.7
INO80 homolog (S. cerevisiae)
chrX_-_100412587 0.27 ENSMUST00000033567.8
acyl-CoA wax alcohol acyltransferase 2
chr6_-_124965207 0.26 ENSMUST00000148485.1
COP9 (constitutive photomorphogenic) homolog, subunit 7a (Arabidopsis thaliana)
chr3_+_96172327 0.26 ENSMUST00000076372.4
splicing factor 3b, subunit 4
chr2_+_102706356 0.25 ENSMUST00000123759.1
ENSMUST00000111212.1
ENSMUST00000005220.4
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr1_+_131910458 0.25 ENSMUST00000062264.6
nuclear casein kinase and cyclin-dependent kinase substrate 1
chr2_+_112265809 0.23 ENSMUST00000110991.2
solute carrier family 12, member 6
chr19_-_57008187 0.22 ENSMUST00000118800.1
ENSMUST00000111584.2
ENSMUST00000122359.1
ENSMUST00000148049.1
actin filament associated protein 1-like 2
chr4_-_106727930 0.22 ENSMUST00000106770.1
ENSMUST00000145044.1
maestro heat-like repeat family member 7
chr5_+_137630116 0.22 ENSMUST00000175968.1
leucine-rich repeats and calponin homology (CH) domain containing 4
chr7_-_134364859 0.21 ENSMUST00000172947.1
DNA segment, Chr 7, ERATO Doi 443, expressed
chr6_+_129533183 0.21 ENSMUST00000032264.6
gamma-aminobutyric acid (GABA) A receptor-associated protein-like 1
chr10_+_81136223 0.21 ENSMUST00000048128.8
zinc finger and BTB domain containing 7a
chr6_+_120836201 0.20 ENSMUST00000009256.2
BCL2-like 13 (apoptosis facilitator)
chr5_+_108065742 0.18 ENSMUST00000081567.4
ENSMUST00000170319.1
ENSMUST00000112626.1
metal response element binding transcription factor 2
chr17_+_28177339 0.18 ENSMUST00000073534.2
ENSMUST00000002318.1
zinc finger protein 523
chr2_+_158794807 0.18 ENSMUST00000029186.7
ENSMUST00000109478.2
ENSMUST00000156893.1
DEAH (Asp-Glu-Ala-His) box polypeptide 35
chr4_+_148000722 0.18 ENSMUST00000103230.4
natriuretic peptide type A
chr4_+_57845240 0.18 ENSMUST00000102903.1
ENSMUST00000107598.3
A kinase (PRKA) anchor protein 2
chr7_-_35802968 0.17 ENSMUST00000061586.4
zinc finger protein 507
chr7_-_105600103 0.17 ENSMUST00000033185.8
hemopexin
chr1_+_167618246 0.17 ENSMUST00000111380.1
retinoid X receptor gamma
chr12_-_113260217 0.16 ENSMUST00000178282.1
immunoglobulin heavy constant alpha
chr4_-_41048124 0.16 ENSMUST00000030136.6
aquaporin 7
chr16_+_31663935 0.16 ENSMUST00000100001.3
ENSMUST00000064477.7
discs, large homolog 1 (Drosophila)
chr11_-_74590065 0.15 ENSMUST00000145524.1
ENSMUST00000047488.7
RAP1 GTPase activating protein 2
chr4_-_58912678 0.14 ENSMUST00000144512.1
ENSMUST00000102889.3
ENSMUST00000055822.8
expressed sequence AI314180
chr14_-_118706180 0.14 ENSMUST00000036554.6
ENSMUST00000166646.1
ATP-binding cassette, sub-family C (CFTR/MRP), member 4
chr12_-_111713185 0.14 ENSMUST00000054636.6
BCL2-associated athanogene 5
chr11_+_105092194 0.13 ENSMUST00000021029.5
EF-hand calcium binding domain 3
chr6_-_124965403 0.12 ENSMUST00000129446.1
ENSMUST00000032220.8
COP9 (constitutive photomorphogenic) homolog, subunit 7a (Arabidopsis thaliana)
chr3_+_38886940 0.12 ENSMUST00000061260.7
FAT tumor suppressor homolog 4 (Drosophila)
chr12_-_111712909 0.12 ENSMUST00000160576.1
BCL2-associated athanogene 5
chr10_-_128547722 0.12 ENSMUST00000040572.3
zinc finger CCCH type containing 10
chr2_+_72054598 0.12 ENSMUST00000028525.5
Rap guanine nucleotide exchange factor (GEF) 4
chr10_-_17947997 0.11 ENSMUST00000037879.6
headcase homolog (Drosophila)
chr17_-_75551838 0.10 ENSMUST00000112507.3
family with sequence similarity 98, member A
chr7_-_45725787 0.10 ENSMUST00000094424.3
sperm acrosome associated 4
chr12_+_86241848 0.10 ENSMUST00000071106.4
G patch domain containing 2 like
chr6_-_88446491 0.10 ENSMUST00000165242.1
eukaryotic elongation factor, selenocysteine-tRNA-specific
chr1_-_191164815 0.10 ENSMUST00000171798.1
family with sequence similarity 71, member A
chr11_+_97315716 0.09 ENSMUST00000019026.3
ENSMUST00000132168.1
mitochondrial ribosomal protein L45
chr3_+_94837533 0.09 ENSMUST00000107270.2
pogo transposable element with ZNF domain
chr16_+_31663841 0.08 ENSMUST00000115201.1
discs, large homolog 1 (Drosophila)
chr11_+_44519405 0.08 ENSMUST00000101327.2
ring finger protein 145
chrX_+_10485121 0.07 ENSMUST00000076354.6
ENSMUST00000115526.1
tetraspanin 7
chrX_-_101263986 0.07 ENSMUST00000101358.2
predicted gene 614
chr8_+_72135247 0.07 ENSMUST00000003575.9
tropomyosin 4
chr19_+_8883910 0.07 ENSMUST00000177826.1
predicted gene, 21743
chr13_-_54688264 0.06 ENSMUST00000150626.1
ENSMUST00000134177.1
ring finger protein 44
chr1_+_131688670 0.05 ENSMUST00000064679.2
ENSMUST00000064664.3
ENSMUST00000136247.1
RIKEN cDNA 5430435G22 gene
chr8_+_12573017 0.05 ENSMUST00000010579.6
sperm acrosome associated 7
chr13_+_5861489 0.05 ENSMUST00000000080.6
Kruppel-like factor 6
chr7_+_19212521 0.05 ENSMUST00000060225.4
G protein-coupled receptor 4
chr14_-_16243309 0.03 ENSMUST00000112625.1
3-oxoacyl-ACP synthase, mitochondrial
chr14_+_21500879 0.03 ENSMUST00000182964.1
K(lysine) acetyltransferase 6B
chr12_+_119945957 0.03 ENSMUST00000058644.8
transmembrane protein 196
chr1_+_84839833 0.02 ENSMUST00000097672.3
F-box protein 36
chr7_+_140093388 0.01 ENSMUST00000026540.8
proline-rich acidic protein 1

Network of associatons between targets according to the STRING database.

First level regulatory network of Rxrb

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 5.8 GO:0033227 dsRNA transport(GO:0033227)
0.6 1.7 GO:0051329 interphase(GO:0051325) mitotic interphase(GO:0051329)
0.5 1.6 GO:2000387 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of integrin activation(GO:0033624) negative regulation of interleukin-1 alpha secretion(GO:0050712) regulation of matrix metallopeptidase secretion(GO:1904464) matrix metallopeptidase secretion(GO:1990773) positive regulation of ovarian follicle development(GO:2000386) regulation of antral ovarian follicle growth(GO:2000387) positive regulation of antral ovarian follicle growth(GO:2000388) negative regulation of eosinophil migration(GO:2000417)
0.5 2.0 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.4 2.1 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.4 2.2 GO:1904587 response to glycoprotein(GO:1904587)
0.3 1.2 GO:0035905 ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910)
0.2 2.0 GO:0070314 G1 to G0 transition(GO:0070314)
0.2 1.1 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.2 0.9 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.2 0.8 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.2 0.5 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.1 0.8 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.1 2.0 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.1 1.3 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.1 1.3 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.1 0.9 GO:0098909 bundle of His cell to Purkinje myocyte signaling(GO:0086028) bundle of His cell action potential(GO:0086043) regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.1 3.0 GO:0015813 L-glutamate transport(GO:0015813)
0.1 0.5 GO:0021539 subthalamus development(GO:0021539)
0.1 0.7 GO:0061084 negative regulation of protein refolding(GO:0061084)
0.1 0.2 GO:0019046 release from viral latency(GO:0019046) regulation of DNA strand elongation(GO:0060382)
0.1 1.9 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.1 0.3 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.1 0.2 GO:1903760 regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760)
0.1 0.2 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.1 1.0 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.1 0.9 GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.1 1.2 GO:0000338 protein deneddylation(GO:0000338)
0.1 0.2 GO:1903764 regulation of potassium ion export across plasma membrane(GO:1903764)
0.1 1.9 GO:0032469 endoplasmic reticulum calcium ion homeostasis(GO:0032469)
0.1 0.4 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.1 1.3 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 1.1 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.3 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.0 0.3 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.3 GO:0010025 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.0 0.2 GO:0015886 heme transport(GO:0015886)
0.0 1.2 GO:0033622 integrin activation(GO:0033622)
0.0 0.5 GO:0048733 sebaceous gland development(GO:0048733)
0.0 0.2 GO:0015793 glycerol transport(GO:0015793)
0.0 1.1 GO:0034391 smooth muscle cell apoptotic process(GO:0034390) regulation of smooth muscle cell apoptotic process(GO:0034391)
0.0 2.0 GO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0008631)
0.0 0.1 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.0 0.1 GO:1904457 positive regulation of neuronal action potential(GO:1904457)
0.0 0.4 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.6 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.5 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 0.2 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.5 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 1.7 GO:0046888 negative regulation of hormone secretion(GO:0046888)
0.0 0.2 GO:0045199 maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0 0.2 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 1.9 GO:0043149 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.0 0.8 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.1 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.3 GO:0030903 notochord development(GO:0030903)
0.0 0.0 GO:0072008 glomerular mesangial cell differentiation(GO:0072008) glomerular mesangial cell development(GO:0072144)
0.0 1.1 GO:2001237 negative regulation of extrinsic apoptotic signaling pathway(GO:2001237)
0.0 0.3 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.9 GO:0071953 elastic fiber(GO:0071953)
0.2 1.9 GO:0071439 clathrin complex(GO:0071439)
0.1 0.4 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.1 0.9 GO:0031080 nuclear pore outer ring(GO:0031080)
0.1 1.7 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 2.0 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.5 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.0 2.0 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.1 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.4 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.5 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.2 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 1.5 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.1 GO:0044316 cone cell pedicle(GO:0044316)
0.0 0.5 GO:0005916 fascia adherens(GO:0005916)
0.0 0.4 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 1.3 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 2.0 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.2 GO:0042629 mast cell granule(GO:0042629)
0.0 0.9 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.2 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.9 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.7 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 1.7 GO:0016605 PML body(GO:0016605)
0.0 0.6 GO:0097440 apical dendrite(GO:0097440)
0.0 1.7 GO:0000776 kinetochore(GO:0000776)
0.0 1.0 GO:0005581 collagen trimer(GO:0005581)
0.0 1.3 GO:0000793 condensed chromosome(GO:0000793)
0.0 0.2 GO:0000421 autophagosome membrane(GO:0000421)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 5.8 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.2 1.6 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.2 3.0 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.2 2.0 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.2 1.3 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.2 2.2 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.1 2.4 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 3.1 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.8 GO:0001851 complement component C3b binding(GO:0001851)
0.1 0.5 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 1.1 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.1 0.5 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.1 0.3 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.1 0.2 GO:0035827 rubidium ion transmembrane transporter activity(GO:0035827)
0.1 1.9 GO:0097602 cullin family protein binding(GO:0097602)
0.1 0.4 GO:0034603 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.1 0.5 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 0.3 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 1.9 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 1.3 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.2 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.2 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.6 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.5 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.2 GO:0015254 glycerol channel activity(GO:0015254)
0.0 0.5 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 2.0 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.6 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 1.1 GO:0001671 ATPase activator activity(GO:0001671)
0.0 1.3 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 1.0 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.2 GO:0030957 Tat protein binding(GO:0030957)
0.0 1.2 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.9 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.5 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.2 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.2 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.9 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.1 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.0 0.2 GO:0003796 lysozyme activity(GO:0003796)
0.0 1.1 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.2 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.8 GO:0019843 rRNA binding(GO:0019843)
0.0 0.5 GO:0005109 frizzled binding(GO:0005109)
0.0 0.8 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.2 GO:0051428 peptide hormone receptor binding(GO:0051428)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.1 PID ATM PATHWAY ATM pathway
0.0 2.4 PID AURORA B PATHWAY Aurora B signaling
0.0 2.2 PID ARF6 PATHWAY Arf6 signaling events
0.0 1.1 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.2 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 1.3 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.6 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.2 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.3 3.1 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.2 1.7 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.2 1.7 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.1 1.6 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.1 2.1 REACTOME KINESINS Genes involved in Kinesins
0.1 0.5 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.1 0.8 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 0.9 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.4 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 1.3 REACTOME CA DEPENDENT EVENTS Genes involved in Ca-dependent events
0.0 0.9 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 1.1 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 1.1 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.2 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 1.2 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.5 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.5 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction