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12D miR HR13_24

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Results for Ascl2

Z-value: 2.02

Motif logo

Transcription factors associated with Ascl2

Gene Symbol Gene ID Gene Info
ENSMUSG00000009248.5 achaete-scute family bHLH transcription factor 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Ascl2mm10_v2_chr7_-_142969238_142969264-0.539.0e-02Click!

Activity profile of Ascl2 motif

Sorted Z-values of Ascl2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_128206346 8.52 ENSMUST00000033049.7
cytochrome c oxidase subunit VIa polypeptide 2
chr15_-_71727815 4.09 ENSMUST00000022953.8
family with sequence similarity 135, member B
chr12_-_17176888 3.97 ENSMUST00000170580.1
potassium voltage-gated channel, subfamily F, member 1
chr11_-_120648104 3.75 ENSMUST00000026134.2
myeloid-associated differentiation marker-like 2
chr11_+_69965396 3.62 ENSMUST00000018713.6
claudin 7
chr6_+_107529717 3.55 ENSMUST00000049285.8
leucine rich repeat protein 1, neuronal
chr4_-_138367966 3.47 ENSMUST00000030535.3
cytidine deaminase
chr4_-_141846359 3.22 ENSMUST00000037059.10
chymotrypsin C (caldecrin)
chr7_-_143074037 3.22 ENSMUST00000136602.1
transient receptor potential cation channel, subfamily M, member 5
chr10_+_127866457 3.17 ENSMUST00000092058.3
cDNA sequence BC089597
chr4_-_141846277 3.02 ENSMUST00000105781.1
chymotrypsin C (caldecrin)
chr9_-_62537036 2.83 ENSMUST00000048043.5
coronin, actin binding protein, 2B
chr10_+_69212634 2.80 ENSMUST00000020101.5
Rho-related BTB domain containing 1
chr4_-_8239034 2.72 ENSMUST00000066674.7
carbonic anhydrase 8
chr2_-_25196759 2.63 ENSMUST00000081869.6
torsin family 4, member A
chr5_+_91139591 2.51 ENSMUST00000031325.4
amphiregulin
chr9_-_45204083 2.48 ENSMUST00000034599.8
transmembrane protease, serine 4
chr9_-_62510498 2.34 ENSMUST00000164246.2
coronin, actin binding protein, 2B
chrX_+_143518671 2.29 ENSMUST00000134402.1
p21 protein (Cdc42/Rac)-activated kinase 3
chr16_-_22439570 2.28 ENSMUST00000170393.1
ets variant gene 5
chr4_-_130275542 2.27 ENSMUST00000154846.1
ENSMUST00000105996.1
serine incorporator 2
chr15_-_101850778 2.25 ENSMUST00000023790.3
keratin 1
chr7_-_66427469 2.22 ENSMUST00000015278.7
aldehyde dehydrogenase family 1, subfamily A3
chr4_-_130275213 2.18 ENSMUST00000122374.1
serine incorporator 2
chr10_+_34483400 2.15 ENSMUST00000019913.7
ENSMUST00000170771.1
fyn-related kinase
chr16_-_32797413 2.14 ENSMUST00000115116.1
ENSMUST00000041123.8
mucin 20
chr1_-_156674290 2.10 ENSMUST00000079625.4
torsin family 3, member A
chr11_-_119086221 2.06 ENSMUST00000026665.7
chromobox 4
chr12_+_26469204 2.04 ENSMUST00000020969.3
cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
chrX_+_143518576 1.98 ENSMUST00000033640.7
p21 protein (Cdc42/Rac)-activated kinase 3
chr4_+_58943575 1.97 ENSMUST00000107554.1
zinc finger with KRAB and SCAN domains 16
chr8_-_41374602 1.93 ENSMUST00000110417.1
ENSMUST00000034000.8
ENSMUST00000143057.1
N-acylsphingosine amidohydrolase 1
chr17_+_5492558 1.82 ENSMUST00000089185.4
zinc finger, DHHC domain containing 14
chr12_-_113422730 1.81 ENSMUST00000177715.1
ENSMUST00000103426.1
immunoglobulin heavy constant mu
chr5_-_131538687 1.79 ENSMUST00000161374.1
autism susceptibility candidate 2
chr13_-_103096818 1.78 ENSMUST00000166336.1
microtubule associated serine/threonine kinase family member 4
chr2_+_34772089 1.78 ENSMUST00000028222.6
ENSMUST00000100171.2
heat shock protein 5
chr18_-_82406777 1.76 ENSMUST00000065224.6
galanin receptor 1
chr5_-_69341699 1.75 ENSMUST00000054095.4
potassium channel tetramerisation domain containing 8
chr5_+_102845007 1.75 ENSMUST00000070000.4
Rho GTPase activating protein 24
chr7_-_127993831 1.73 ENSMUST00000033056.3
PYD and CARD domain containing
chr1_-_84696182 1.73 ENSMUST00000049126.6
delta/notch-like EGF-related receptor
chr18_-_61536522 1.72 ENSMUST00000171629.1
Rho guanine nucleotide exchange factor (GEF) 37
chr19_-_5349574 1.72 ENSMUST00000025764.5
cystatin E/M
chr1_-_14918862 1.69 ENSMUST00000041447.4
transient receptor potential cation channel, subfamily A, member 1
chr3_+_106486009 1.67 ENSMUST00000183271.1
ENSMUST00000061206.3
DENN/MADD domain containing 2D
chr2_+_174760619 1.66 ENSMUST00000029030.2
endothelin 3
chr11_+_96929260 1.64 ENSMUST00000054311.5
ENSMUST00000107636.3
proline rich 15-like
chr10_-_128401218 1.62 ENSMUST00000042666.5
solute carrier family 39 (metal ion transporter), member 5
chr1_+_75549581 1.59 ENSMUST00000154101.1
solute carrier family 4 (anion exchanger), member 3
chr5_+_35757875 1.58 ENSMUST00000101280.3
ENSMUST00000054598.5
ENSMUST00000114205.1
ENSMUST00000114206.2
actin-binding LIM protein 2
chr5_+_24428208 1.58 ENSMUST00000115049.2
solute carrier family 4 (anion exchanger), member 2
chr11_+_96929367 1.56 ENSMUST00000062172.5
proline rich 15-like
chr18_-_44662251 1.54 ENSMUST00000164666.1
mutated in colorectal cancers
chr7_+_44207307 1.54 ENSMUST00000077354.4
kallikrein 1-related pepidase b4
chr15_-_32244632 1.53 ENSMUST00000181536.1
RIKEN cDNA 0610007N19
chr1_-_130715734 1.52 ENSMUST00000066863.6
ENSMUST00000050406.4
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
chr15_-_58364148 1.52 ENSMUST00000068515.7
annexin A13
chr13_-_119408985 1.50 ENSMUST00000099149.3
ENSMUST00000069902.6
ENSMUST00000109204.1
nicotinamide nucleotide transhydrogenase
chr4_-_148149684 1.49 ENSMUST00000126615.1
F-box protein 6
chr15_+_59315030 1.48 ENSMUST00000022977.7
squalene epoxidase
chr10_-_61147659 1.48 ENSMUST00000092498.5
ENSMUST00000137833.1
ENSMUST00000155919.1
sphingosine phosphate lyase 1
chr11_+_53519920 1.48 ENSMUST00000147912.1
septin 8
chr1_+_120340569 1.47 ENSMUST00000037286.8
complement component 1, q subcomponent-like 2
chr10_-_61147625 1.47 ENSMUST00000122259.1
sphingosine phosphate lyase 1
chr2_-_170406501 1.47 ENSMUST00000154650.1
breast carcinoma amplified sequence 1
chr5_+_90759299 1.47 ENSMUST00000031318.4
chemokine (C-X-C motif) ligand 5
chr4_+_133553370 1.43 ENSMUST00000042706.2
nuclear receptor subfamily 0, group B, member 2
chr7_+_44225430 1.42 ENSMUST00000075162.3
kallikrein 1
chr11_+_53519871 1.40 ENSMUST00000120878.2
septin 8
chr15_+_59315088 1.39 ENSMUST00000100640.4
squalene epoxidase
chr11_+_71749914 1.39 ENSMUST00000150531.1
WSC domain containing 1
chr9_+_109096659 1.37 ENSMUST00000130366.1
plexin B1
chr7_-_131322292 1.37 ENSMUST00000046611.7
CUB and zona pellucida-like domains 1
chr15_-_98728120 1.34 ENSMUST00000003445.6
FK506 binding protein 11
chr13_-_52981027 1.32 ENSMUST00000071065.7
nuclear factor, interleukin 3, regulated
chr7_+_30977043 1.30 ENSMUST00000058093.4
family with sequence similarity 187, member B
chr17_-_87282793 1.29 ENSMUST00000146560.2
RIKEN cDNA 4833418N02 gene
chr11_+_98664341 1.29 ENSMUST00000017348.2
gasdermin A
chr4_-_130275523 1.29 ENSMUST00000146478.1
serine incorporator 2
chr6_+_125349699 1.29 ENSMUST00000032491.8
tumor necrosis factor receptor superfamily, member 1a
chr1_-_162866502 1.27 ENSMUST00000046049.7
flavin containing monooxygenase 1
chr6_-_124733121 1.27 ENSMUST00000112484.3
protein tyrosine phosphatase, non-receptor type 6
chr19_-_6015152 1.26 ENSMUST00000025891.8
calpain 1
chr5_+_149411749 1.26 ENSMUST00000093110.5
mesenteric estrogen dependent adipogenesis
chr10_+_116986314 1.25 ENSMUST00000020378.4
bestrophin 3
chr15_+_99591028 1.24 ENSMUST00000169082.1
aquaporin 5
chr10_-_75560330 1.24 ENSMUST00000051129.9
family with sequence similarity 211, member B
chr11_+_115163333 1.24 ENSMUST00000021077.3
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1
chr7_+_139213239 1.22 ENSMUST00000106104.1
leucine rich repeat containing 27
chr9_-_43239816 1.22 ENSMUST00000034512.5
OAF homolog (Drosophila)
chr6_-_148444336 1.20 ENSMUST00000060095.8
ENSMUST00000100772.3
transmembrane and tetratricopeptide repeat containing 1
chr3_+_27182965 1.19 ENSMUST00000046515.8
neutral cholesterol ester hydrolase 1
chr12_+_112678803 1.18 ENSMUST00000174780.1
ENSMUST00000169593.1
ENSMUST00000173942.1
zinc finger and BTB domain containing 42
chr7_+_44198191 1.17 ENSMUST00000085450.2
kallikrein 1-related peptidase b3
chr3_+_27182994 1.16 ENSMUST00000091284.4
neutral cholesterol ester hydrolase 1
chr12_+_17690793 1.16 ENSMUST00000071858.3
hippocalcin-like 1
chr7_+_44188205 1.16 ENSMUST00000073713.6
kallikrein 1-related peptidase b24
chr14_+_33923582 1.15 ENSMUST00000168727.1
growth differentiation factor 10
chr5_+_135168382 1.14 ENSMUST00000111187.3
ENSMUST00000111188.1
B cell CLL/lymphoma 7B
chr8_+_62951195 1.14 ENSMUST00000118003.1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan 3
chr13_-_62888282 1.13 ENSMUST00000092888.4
fructose bisphosphatase 1
chr15_-_100599983 1.13 ENSMUST00000073837.6
POU domain, class 6, transcription factor 1
chr5_+_35757951 1.12 ENSMUST00000114204.1
ENSMUST00000129347.1
actin-binding LIM protein 2
chr9_-_108567336 1.12 ENSMUST00000074208.4
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 3
chrX_-_112698642 1.11 ENSMUST00000039887.3
premature ovarian failure 1B
chr1_-_88205674 1.08 ENSMUST00000119972.2
DnaJ (Hsp40) homolog, subfamily B, member 3
chr7_+_78913765 1.08 ENSMUST00000038142.8
interferon-stimulated protein
chr4_-_62434722 1.07 ENSMUST00000107454.1
ring finger protein 183
chr7_-_99626936 1.07 ENSMUST00000178124.1
predicted gene 4980
chr1_-_167393826 1.07 ENSMUST00000028005.2
microsomal glutathione S-transferase 3
chr17_-_21845759 1.06 ENSMUST00000084141.4
zinc finger protein 820
chr17_-_57228003 1.06 ENSMUST00000177046.1
ENSMUST00000024988.8
complement component 3
chr6_+_56017489 1.06 ENSMUST00000052827.4
protein phosphatase 1, regulatory subunit 17
chr8_+_3665747 1.06 ENSMUST00000014118.2
RIKEN cDNA 1810033B17 gene
chr9_+_107975529 1.05 ENSMUST00000035216.4
ubiquitin-like modifier activating enzyme 7
chr7_+_80246375 1.05 ENSMUST00000058266.6
tubulin tyrosine ligase-like family, member 13
chr2_+_174760781 1.04 ENSMUST00000140908.1
endothelin 3
chr8_-_111691002 1.04 ENSMUST00000034435.5
chymotrypsinogen B1
chr10_+_11343387 1.04 ENSMUST00000069106.4
epilepsy, progressive myoclonic epilepsy, type 2 gene alpha
chr1_+_74854954 1.04 ENSMUST00000160379.2
cyclin-dependent kinase 5, regulatory subunit 2 (p39)
chr15_+_102144362 1.04 ENSMUST00000023807.6
insulin-like growth factor binding protein 6
chr5_+_135168283 1.01 ENSMUST00000031692.5
B cell CLL/lymphoma 7B
chr5_-_107726017 1.01 ENSMUST00000159263.2
growth factor independent 1
chr4_-_133263042 1.01 ENSMUST00000105908.3
ENSMUST00000030674.7
synaptotagmin-like 1
chr17_-_57247632 1.00 ENSMUST00000005975.6
G protein-coupled receptor 108
chr2_-_26933781 0.99 ENSMUST00000154651.1
ENSMUST00000015011.3
surfeit gene 4
chr5_-_122502192 0.99 ENSMUST00000179939.1
ENSMUST00000177974.1
ENSMUST00000031423.8
ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
chr11_-_59182810 0.98 ENSMUST00000108793.2
gap junction protein, gamma 2
chr7_+_126950837 0.98 ENSMUST00000106332.1
seizure related 6 homolog like 2
chr7_+_122289297 0.98 ENSMUST00000064989.5
ENSMUST00000064921.4
protein kinase C, beta
chr7_-_67803489 0.97 ENSMUST00000181235.1
RIKEN cDNA 4833412C05 gene
chr4_-_154160632 0.96 ENSMUST00000105639.3
ENSMUST00000030896.8
transformation related protein 63 regulated like
chr15_-_84855093 0.95 ENSMUST00000016768.5
PHD finger protein 21B
chr3_+_108284089 0.94 ENSMUST00000102632.4
sortilin 1
chr10_+_128270546 0.94 ENSMUST00000105238.3
ENSMUST00000085708.2
signal transducer and activator of transcription 2
chr19_-_56822161 0.94 ENSMUST00000118592.1
RIKEN cDNA A630007B06 gene
chr12_+_73286868 0.93 ENSMUST00000153941.1
ENSMUST00000122920.1
ENSMUST00000101313.3
solute carrier family 38, member 6
chr3_-_129969989 0.93 ENSMUST00000146340.1
coiled-coil domain containing 109B
chr9_-_53975246 0.93 ENSMUST00000048409.7
ELMO/CED-12 domain containing 1
chr6_-_29179584 0.93 ENSMUST00000159200.1
proline-rich transmembrane protein 4
chr7_+_3290553 0.91 ENSMUST00000096744.5
myeloid-associated differentiation marker
chr1_+_162639148 0.91 ENSMUST00000028020.9
myocilin
chr1_+_160044564 0.90 ENSMUST00000168359.1
RIKEN cDNA 4930523C07 gene
chr11_-_5837760 0.90 ENSMUST00000109837.1
polymerase (DNA directed), mu
chr10_-_128673896 0.89 ENSMUST00000054764.7
sulfite oxidase
chr2_+_121449362 0.89 ENSMUST00000110615.1
ENSMUST00000099475.5
small EDRK-rich factor 2
chr4_-_147642496 0.88 ENSMUST00000133006.1
ENSMUST00000037565.7
ENSMUST00000105720.1
RIKEN cDNA 2610305D13 gene
chr19_-_41385070 0.88 ENSMUST00000059672.7
phosphoinositide-3-kinase adaptor protein 1
chr3_-_129970152 0.88 ENSMUST00000029624.8
coiled-coil domain containing 109B
chr1_+_127868773 0.88 ENSMUST00000037649.5
RAB3 GTPase activating protein subunit 1
chr1_+_180935022 0.87 ENSMUST00000037361.8
left right determination factor 1
chr7_+_139212974 0.87 ENSMUST00000016124.8
leucine rich repeat containing 27
chr2_-_168741752 0.87 ENSMUST00000029060.4
ATPase, class II, type 9A
chr2_+_164403194 0.86 ENSMUST00000017151.1
recombination signal binding protein for immunoglobulin kappa J region-like
chr4_-_147809788 0.86 ENSMUST00000105734.3
ENSMUST00000176201.1
predicted gene 13157
predicted gene 20707
chr4_-_147702553 0.85 ENSMUST00000117638.1
zinc finger protein 534
chrX_+_36328353 0.85 ENSMUST00000016383.3
LON peptidase N-terminal domain and ring finger 3
chr9_-_57836706 0.85 ENSMUST00000164010.1
ENSMUST00000171444.1
ENSMUST00000098686.3
AT rich interactive domain 3B (BRIGHT-like)
chr11_-_114795888 0.85 ENSMUST00000000206.3
BTB (POZ) domain containing 17
chr3_+_132085281 0.84 ENSMUST00000029665.5
dickkopf homolog 2 (Xenopus laevis)
chr1_-_130462680 0.84 ENSMUST00000027650.6
CD55 antigen
chr2_+_125136692 0.82 ENSMUST00000099452.2
cortexin 2
chr4_-_124850670 0.82 ENSMUST00000163946.1
ENSMUST00000106190.3
RIKEN cDNA 1110065P20 gene
chr2_-_27072175 0.82 ENSMUST00000009358.2
transmembrane protein 8C
chr7_+_142471838 0.82 ENSMUST00000038946.2
lymphocyte specific 1
chr8_-_91133942 0.81 ENSMUST00000120213.1
ENSMUST00000109609.2
thymoma viral proto-oncogene 1 interacting protein
chr7_+_139213003 0.81 ENSMUST00000156768.1
leucine rich repeat containing 27
chr5_+_120861421 0.80 ENSMUST00000072476.6
ENSMUST00000171820.1
2'-5' oligoadenylate synthetase 1H
chr11_+_121434913 0.79 ENSMUST00000026175.2
ENSMUST00000092302.4
ENSMUST00000103014.3
fructosamine 3 kinase
chr3_-_75270073 0.79 ENSMUST00000039047.4
serine (or cysteine) peptidase inhibitor, clade I, member 2
chr6_-_52191695 0.79 ENSMUST00000101395.2
homeobox A4
chr6_-_56362356 0.79 ENSMUST00000044505.7
ENSMUST00000166102.1
ENSMUST00000164037.1
ENSMUST00000114327.2
phosphodiesterase 1C
chr16_+_17276662 0.79 ENSMUST00000069420.4
transmembrane protein 191C
chr9_+_72985568 0.79 ENSMUST00000150826.2
ENSMUST00000085350.4
ENSMUST00000140675.1
cell cycle progression 1
chr1_+_194619815 0.78 ENSMUST00000027952.5
plexin A2
chr6_-_72617000 0.78 ENSMUST00000070524.4
trans-golgi network protein
chr4_-_156050465 0.78 ENSMUST00000184684.1
tubulin tyrosine ligase-like family, member 10
chr4_-_124850652 0.78 ENSMUST00000125776.1
RIKEN cDNA 1110065P20 gene
chr7_+_142472080 0.78 ENSMUST00000105966.1
lymphocyte specific 1
chr8_+_92901387 0.78 ENSMUST00000104947.2
calpain, small subunit 2
chr2_-_77170592 0.77 ENSMUST00000164114.2
ENSMUST00000049544.7
coiled-coil domain containing 141
chr1_-_164458345 0.77 ENSMUST00000027863.7
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr10_-_120201558 0.77 ENSMUST00000020448.4
interleukin-1 receptor-associated kinase 3
chr6_+_105677768 0.77 ENSMUST00000089208.2
contactin 4
chr17_-_22166190 0.77 ENSMUST00000080249.5
zinc finger protein 947
chr4_-_156050785 0.77 ENSMUST00000051509.8
tubulin tyrosine ligase-like family, member 10
chr7_+_121707189 0.76 ENSMUST00000065310.2
RIKEN cDNA 1700069B07 gene
chr4_-_46536134 0.76 ENSMUST00000046897.6
tripartite motif-containing 14
chr16_-_74411292 0.76 ENSMUST00000117200.1
roundabout homolog 2 (Drosophila)
chr5_+_114568016 0.76 ENSMUST00000043650.7
family with sequence similarity 222, member A
chr8_-_91134027 0.75 ENSMUST00000125257.1
thymoma viral proto-oncogene 1 interacting protein
chr11_+_45980309 0.75 ENSMUST00000049038.3
SRY-box containing gene 30
chr6_+_105677745 0.75 ENSMUST00000113261.2
ENSMUST00000113264.2
contactin 4
chr2_-_144011202 0.75 ENSMUST00000016072.5
ENSMUST00000037875.5
ribosome binding protein 1
chrX_+_95711641 0.75 ENSMUST00000150123.1
zinc finger CCCH-type containing 12B
chr13_-_62858364 0.74 ENSMUST00000021907.7
fructose bisphosphatase 2
chr7_+_141461728 0.74 ENSMUST00000167491.1
ENSMUST00000165194.1
EF-hand calcium binding domain 4A
chr15_-_75888754 0.74 ENSMUST00000184858.1
maestro heat-like repeat family member 6
chr16_-_17576206 0.73 ENSMUST00000090165.4
ENSMUST00000164623.1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 4

Network of associatons between targets according to the STRING database.

First level regulatory network of Ascl2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.5 GO:0009972 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.8 5.7 GO:1904222 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.7 2.2 GO:0060166 olfactory pit development(GO:0060166)
0.7 2.0 GO:0009196 dUDP biosynthetic process(GO:0006227) pyrimidine nucleoside diphosphate metabolic process(GO:0009138) pyrimidine nucleoside diphosphate biosynthetic process(GO:0009139) pyrimidine deoxyribonucleoside diphosphate metabolic process(GO:0009196) pyrimidine deoxyribonucleoside diphosphate biosynthetic process(GO:0009197) dUDP metabolic process(GO:0046077)
0.7 2.0 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.7 8.5 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.6 2.5 GO:0060598 dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis(GO:0060598)
0.6 1.9 GO:0046351 disaccharide biosynthetic process(GO:0046351)
0.6 1.8 GO:0002343 peripheral B cell selection(GO:0002343) B cell affinity maturation(GO:0002344)
0.6 1.8 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.6 1.8 GO:0021589 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)
0.6 1.8 GO:0051464 positive regulation of cortisol secretion(GO:0051464)
0.6 1.7 GO:0002588 myeloid dendritic cell activation involved in immune response(GO:0002277) positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002582) positive regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002588)
0.5 1.6 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
0.5 1.5 GO:0070948 regulation of neutrophil mediated cytotoxicity(GO:0070948) regulation of neutrophil mediated killing of symbiont cell(GO:0070949)
0.5 2.8 GO:0050968 detection of chemical stimulus involved in sensory perception of pain(GO:0050968)
0.5 2.7 GO:0003100 regulation of systemic arterial blood pressure by endothelin(GO:0003100)
0.4 1.2 GO:0042939 glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
0.4 2.3 GO:0098728 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.3 1.7 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.3 1.4 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.3 0.9 GO:0097051 establishment of protein localization to endoplasmic reticulum membrane(GO:0097051)
0.3 2.2 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.3 0.8 GO:0030450 regulation of complement activation, classical pathway(GO:0030450)
0.3 1.4 GO:0070103 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) regulation of interleukin-6-mediated signaling pathway(GO:0070103)
0.3 0.8 GO:0021934 hindbrain tangential cell migration(GO:0021934)
0.3 1.0 GO:0021586 pons maturation(GO:0021586)
0.3 0.8 GO:1903279 regulation of calcium:sodium antiporter activity(GO:1903279)
0.3 1.5 GO:0018094 protein polyglycylation(GO:0018094)
0.2 0.7 GO:0071314 cellular response to cocaine(GO:0071314)
0.2 0.9 GO:0014734 skeletal muscle hypertrophy(GO:0014734)
0.2 1.1 GO:0034421 post-translational protein acetylation(GO:0034421)
0.2 1.1 GO:0021564 vagus nerve development(GO:0021564)
0.2 0.7 GO:0006011 UDP-glucose metabolic process(GO:0006011)
0.2 1.1 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
0.2 1.1 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.2 0.6 GO:1903903 positive regulation of keratinocyte apoptotic process(GO:1902174) regulation of establishment of T cell polarity(GO:1903903)
0.2 0.6 GO:0007439 ectodermal digestive tract development(GO:0007439) embryonic ectodermal digestive tract development(GO:0048611)
0.2 0.8 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.2 1.0 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.2 1.8 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.2 0.8 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.2 3.6 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.2 0.9 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.2 0.9 GO:0015692 vanadium ion transport(GO:0015676) lead ion transport(GO:0015692)
0.2 0.9 GO:0044849 estrous cycle(GO:0044849)
0.2 1.1 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.2 1.1 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.2 0.9 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.2 0.5 GO:0009446 putrescine biosynthetic process(GO:0009446)
0.2 3.0 GO:0033327 Leydig cell differentiation(GO:0033327)
0.2 0.2 GO:0072098 intermediate mesoderm development(GO:0048389) pattern specification involved in mesonephros development(GO:0061227) anterior/posterior pattern specification involved in kidney development(GO:0072098)
0.2 0.8 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.2 0.5 GO:0098917 positive regulation of the force of heart contraction(GO:0098735) retrograde trans-synaptic signaling(GO:0098917) trans-synaptic signaling by soluble gas(GO:0099543) regulation of adrenergic receptor signaling pathway involved in heart process(GO:1901204)
0.2 4.3 GO:0010763 positive regulation of fibroblast migration(GO:0010763)
0.2 1.1 GO:0098909 regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.2 0.5 GO:0090004 positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.2 1.4 GO:0006013 mannose metabolic process(GO:0006013)
0.2 2.1 GO:0048012 hepatocyte growth factor receptor signaling pathway(GO:0048012)
0.1 0.6 GO:0021660 rhombomere formation(GO:0021594) rhombomere 3 formation(GO:0021660) rhombomere 5 morphogenesis(GO:0021664) rhombomere 5 formation(GO:0021666)
0.1 1.2 GO:0015670 carbon dioxide transport(GO:0015670)
0.1 1.4 GO:0000255 allantoin metabolic process(GO:0000255) creatinine metabolic process(GO:0046449)
0.1 1.1 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.1 0.4 GO:0090157 lysosomal microautophagy(GO:0016237) piecemeal microautophagy of nucleus(GO:0034727) suppression by virus of host autophagy(GO:0039521) negative regulation of sphingolipid biosynthesis involved in cellular sphingolipid homeostasis(GO:0090157)
0.1 1.5 GO:0033133 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.1 0.1 GO:0006713 glucocorticoid catabolic process(GO:0006713)
0.1 0.7 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.1 0.3 GO:2000097 regulation of lipoprotein oxidation(GO:0034442) negative regulation of lipoprotein oxidation(GO:0034443) regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.1 1.7 GO:0007220 Notch receptor processing(GO:0007220)
0.1 0.7 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.1 0.5 GO:0009814 defense response, incompatible interaction(GO:0009814) defense response to bacterium, incompatible interaction(GO:0009816) regulation of defense response to bacterium, incompatible interaction(GO:1902477)
0.1 0.9 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.1 0.5 GO:0006868 glutamine transport(GO:0006868)
0.1 0.5 GO:0001830 trophectodermal cell fate commitment(GO:0001830)
0.1 1.0 GO:0046959 habituation(GO:0046959)
0.1 0.8 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.1 0.4 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.1 0.2 GO:0061152 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.1 1.3 GO:0070995 NADPH oxidation(GO:0070995)
0.1 0.2 GO:0043686 co-translational protein modification(GO:0043686)
0.1 1.3 GO:0097264 self proteolysis(GO:0097264)
0.1 1.1 GO:1903800 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148) positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.1 0.4 GO:0060447 peripheral nervous system axon regeneration(GO:0014012) bud outgrowth involved in lung branching(GO:0060447)
0.1 0.4 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1 0.3 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.1 0.7 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.1 0.3 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.1 0.3 GO:0050915 sensory perception of sour taste(GO:0050915)
0.1 1.5 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.1 0.7 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.1 0.2 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.1 0.6 GO:0015871 choline transport(GO:0015871)
0.1 0.9 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.1 0.8 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1 0.5 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.1 3.2 GO:0050909 sensory perception of taste(GO:0050909)
0.1 0.5 GO:0016266 O-glycan processing(GO:0016266)
0.1 3.0 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.1 0.7 GO:0014827 intestine smooth muscle contraction(GO:0014827)
0.1 0.7 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.1 0.6 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.1 0.5 GO:0040031 snRNA modification(GO:0040031)
0.1 0.5 GO:0019336 phenol-containing compound catabolic process(GO:0019336)
0.1 0.1 GO:1903972 regulation of macrophage colony-stimulating factor signaling pathway(GO:1902226) regulation of response to macrophage colony-stimulating factor(GO:1903969) regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903972)
0.1 1.0 GO:0010644 cell communication by electrical coupling(GO:0010644)
0.1 1.8 GO:0018345 protein palmitoylation(GO:0018345)
0.1 0.5 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.1 0.5 GO:0007182 common-partner SMAD protein phosphorylation(GO:0007182)
0.1 0.2 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.1 0.5 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.1 0.6 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 0.6 GO:0032119 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.1 0.2 GO:0098528 skeletal muscle fiber differentiation(GO:0098528)
0.1 0.2 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
0.1 0.2 GO:0036118 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.1 0.7 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 0.7 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.1 0.8 GO:0006895 Golgi to endosome transport(GO:0006895)
0.1 0.4 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.1 4.3 GO:0060395 SMAD protein signal transduction(GO:0060395)
0.1 1.7 GO:0006739 NADP metabolic process(GO:0006739)
0.1 0.8 GO:0071941 nitrogen cycle metabolic process(GO:0071941)
0.1 1.1 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.1 0.6 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.1 0.1 GO:0070296 sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.1 0.7 GO:1901550 regulation of endothelial cell development(GO:1901550) regulation of establishment of endothelial barrier(GO:1903140)
0.1 1.2 GO:0006152 purine nucleoside catabolic process(GO:0006152) purine ribonucleoside catabolic process(GO:0046130)
0.0 0.2 GO:0002036 regulation of L-glutamate transport(GO:0002036)
0.0 0.5 GO:0045059 positive thymic T cell selection(GO:0045059)
0.0 0.3 GO:1905146 lysosomal protein catabolic process(GO:1905146)
0.0 0.8 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.7 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0 0.2 GO:0010897 negative regulation of triglyceride catabolic process(GO:0010897)
0.0 1.0 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.0 0.6 GO:0034312 diol biosynthetic process(GO:0034312)
0.0 0.1 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.0 0.5 GO:0042711 maternal behavior(GO:0042711)
0.0 3.8 GO:0051453 regulation of intracellular pH(GO:0051453)
0.0 1.6 GO:0045022 early endosome to late endosome transport(GO:0045022)
0.0 2.7 GO:0016126 sterol biosynthetic process(GO:0016126)
0.0 0.4 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.0 0.7 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.4 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.1 GO:0060139 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139)
0.0 0.3 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.7 GO:0015991 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991)
0.0 0.4 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.9 GO:0070670 response to interleukin-4(GO:0070670) cellular response to interleukin-4(GO:0071353)
0.0 0.9 GO:0060337 type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.0 1.4 GO:0051642 centrosome localization(GO:0051642)
0.0 0.6 GO:0042492 gamma-delta T cell differentiation(GO:0042492)
0.0 0.2 GO:0090527 actin filament reorganization(GO:0090527)
0.0 0.7 GO:0051573 negative regulation of histone H3-K9 methylation(GO:0051573)
0.0 0.5 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.1 GO:0009181 purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
0.0 0.3 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.3 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.1 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.0 0.4 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.0 1.6 GO:0016925 protein sumoylation(GO:0016925)
0.0 1.1 GO:0010257 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 1.0 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.4 GO:0060923 cardiac muscle cell fate commitment(GO:0060923)
0.0 1.5 GO:0010633 negative regulation of epithelial cell migration(GO:0010633)
0.0 0.1 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 0.6 GO:0044062 regulation of excretion(GO:0044062)
0.0 0.2 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.0 1.7 GO:0032024 positive regulation of insulin secretion(GO:0032024)
0.0 0.9 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.1 GO:0040009 replicative cell aging(GO:0001302) regulation of growth rate(GO:0040009) G-quadruplex DNA unwinding(GO:0044806)
0.0 0.3 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.0 0.2 GO:2000465 regulation of glycogen (starch) synthase activity(GO:2000465)
0.0 0.5 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.0 0.1 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.0 0.3 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.0 1.3 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.0 0.9 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.5 GO:1904376 negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376)
0.0 0.3 GO:0045109 intermediate filament organization(GO:0045109)
0.0 0.2 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.1 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.0 0.8 GO:0006040 amino sugar metabolic process(GO:0006040)
0.0 2.8 GO:0071805 potassium ion transmembrane transport(GO:0071805)
0.0 0.1 GO:0015791 polyol transport(GO:0015791)
0.0 0.3 GO:0001921 positive regulation of receptor recycling(GO:0001921)
0.0 0.6 GO:0046677 response to antibiotic(GO:0046677)
0.0 0.1 GO:0048208 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.0 1.1 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.0 0.1 GO:0016340 calcium-dependent cell-matrix adhesion(GO:0016340)
0.0 0.5 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.7 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 1.3 GO:0043271 negative regulation of ion transport(GO:0043271)
0.0 0.2 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.5 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 0.1 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0 1.8 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 1.0 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 3.5 GO:0006874 cellular calcium ion homeostasis(GO:0006874)
0.0 0.2 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.4 GO:0050848 regulation of calcium-mediated signaling(GO:0050848)
0.0 1.1 GO:0007030 Golgi organization(GO:0007030)
0.0 0.3 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 1.0 GO:0048015 phosphatidylinositol-mediated signaling(GO:0048015)
0.0 0.5 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.1 GO:0002634 regulation of germinal center formation(GO:0002634)
0.0 0.9 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 8.5 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.4 1.7 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.4 1.2 GO:0070195 growth hormone receptor complex(GO:0070195)
0.3 1.0 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.3 4.0 GO:0001533 cornified envelope(GO:0001533)
0.3 1.8 GO:0019815 B cell receptor complex(GO:0019815)
0.2 1.6 GO:0070695 FHF complex(GO:0070695)
0.2 0.9 GO:0070826 paraferritin complex(GO:0070826)
0.2 0.6 GO:0032783 ELL-EAF complex(GO:0032783)
0.2 0.6 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.2 1.8 GO:0090533 cation-transporting ATPase complex(GO:0090533)
0.2 0.5 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.2 1.4 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 1.0 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.1 3.3 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 1.8 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 0.6 GO:1990745 EARP complex(GO:1990745)
0.1 1.5 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.1 2.1 GO:0035102 PRC1 complex(GO:0035102)
0.1 0.6 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.1 1.1 GO:0071141 SMAD protein complex(GO:0071141)
0.1 1.0 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.1 1.4 GO:0042589 zymogen granule membrane(GO:0042589)
0.1 1.5 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.6 GO:0030478 actin cap(GO:0030478)
0.1 0.4 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1 0.5 GO:0045098 type III intermediate filament(GO:0045098)
0.1 0.2 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.1 2.5 GO:0030673 axolemma(GO:0030673)
0.1 1.2 GO:0032426 stereocilium tip(GO:0032426)
0.1 0.4 GO:1990462 omegasome(GO:1990462)
0.1 0.9 GO:0035748 myelin sheath abaxonal region(GO:0035748)
0.1 0.2 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.1 0.5 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0 0.7 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 1.1 GO:0030057 desmosome(GO:0030057)
0.0 0.3 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.4 GO:0031983 vesicle lumen(GO:0031983)
0.0 0.1 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.0 1.0 GO:0005922 connexon complex(GO:0005922)
0.0 0.4 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.7 GO:0005767 secondary lysosome(GO:0005767)
0.0 4.2 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.3 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.4 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.4 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.6 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 1.7 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 1.7 GO:0015030 Cajal body(GO:0015030)
0.0 0.8 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 1.0 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 1.0 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.2 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.1 GO:0032389 MutLalpha complex(GO:0032389)
0.0 0.3 GO:0005652 nuclear lamina(GO:0005652)
0.0 0.5 GO:0034451 centriolar satellite(GO:0034451)
0.0 2.1 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 2.9 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.5 GO:0005581 collagen trimer(GO:0005581)
0.0 0.7 GO:0031201 SNARE complex(GO:0031201)
0.0 0.4 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 1.6 GO:0005930 axoneme(GO:0005930)
0.0 0.7 GO:0001772 immunological synapse(GO:0001772)
0.0 0.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.5 GO:0032421 stereocilium bundle(GO:0032421)
0.0 0.2 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 1.2 GO:0005902 microvillus(GO:0005902)
0.0 1.0 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.6 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.2 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.3 GO:0005849 mRNA cleavage factor complex(GO:0005849)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:0030280 structural constituent of epidermis(GO:0030280)
0.7 2.0 GO:0009041 uridylate kinase activity(GO:0009041)
0.7 2.7 GO:0031708 endothelin B receptor binding(GO:0031708)
0.6 1.9 GO:0045159 myosin II binding(GO:0045159)
0.6 3.5 GO:0004126 cytidine deaminase activity(GO:0004126)
0.5 1.5 GO:0070737 protein-glycine ligase activity, elongating(GO:0070737)
0.5 2.8 GO:0097603 temperature-gated ion channel activity(GO:0097603)
0.4 1.7 GO:0008859 exoribonuclease II activity(GO:0008859)
0.4 1.3 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.4 5.7 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.4 1.2 GO:0004903 growth hormone receptor activity(GO:0004903)
0.4 2.2 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.4 1.8 GO:0004966 galanin receptor activity(GO:0004966)
0.4 1.1 GO:0035500 MH2 domain binding(GO:0035500)
0.3 1.9 GO:0017040 ceramidase activity(GO:0017040)
0.3 8.5 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.3 4.4 GO:0019203 carbohydrate phosphatase activity(GO:0019203)
0.3 0.9 GO:0038100 nodal binding(GO:0038100)
0.3 1.1 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.2 1.0 GO:0047710 bis(5'-adenosyl)-triphosphatase activity(GO:0047710)
0.2 0.6 GO:0051373 FATZ binding(GO:0051373)
0.2 4.3 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.2 2.0 GO:0008046 axon guidance receptor activity(GO:0008046)
0.2 3.0 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.2 1.7 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.2 0.9 GO:0015639 cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.2 1.3 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.2 0.5 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.2 0.5 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.2 0.7 GO:0015057 thrombin receptor activity(GO:0015057)
0.2 0.5 GO:0046870 cadmium ion binding(GO:0046870)
0.2 1.5 GO:1901611 phosphatidylglycerol binding(GO:1901611)
0.2 2.4 GO:0042301 phosphate ion binding(GO:0042301)
0.2 3.2 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.2 1.0 GO:1903763 gap junction channel activity involved in cell communication by electrical coupling(GO:1903763)
0.2 1.0 GO:0035184 histone threonine kinase activity(GO:0035184)
0.2 0.9 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.2 2.2 GO:0017154 semaphorin receptor activity(GO:0017154)
0.2 1.1 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 0.9 GO:0043546 molybdopterin cofactor binding(GO:0043546)
0.1 0.5 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.1 0.4 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.1 0.4 GO:0019779 Atg12 activating enzyme activity(GO:0019778) Atg8 activating enzyme activity(GO:0019779)
0.1 0.4 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.1 0.9 GO:0032027 myosin light chain binding(GO:0032027)
0.1 1.3 GO:0039706 co-receptor binding(GO:0039706)
0.1 0.6 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.1 0.6 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
0.1 0.8 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 2.9 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.1 1.5 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 0.8 GO:0048101 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 1.8 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 1.2 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.1 0.9 GO:0001594 trace-amine receptor activity(GO:0001594)
0.1 0.4 GO:0042284 sphingolipid delta-4 desaturase activity(GO:0042284)
0.1 1.4 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.1 0.6 GO:0043559 insulin binding(GO:0043559)
0.1 1.2 GO:0015250 water channel activity(GO:0015250)
0.1 1.5 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.1 0.2 GO:0047936 glucose 1-dehydrogenase [NAD(P)] activity(GO:0047936)
0.1 1.8 GO:0051787 misfolded protein binding(GO:0051787)
0.1 0.8 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1 0.8 GO:0008556 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.1 12.8 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 2.3 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 2.1 GO:0032183 SUMO binding(GO:0032183)
0.1 1.3 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 3.2 GO:0005272 sodium channel activity(GO:0005272)
0.1 0.2 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1 0.5 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.1 0.3 GO:0031800 type 3 metabotropic glutamate receptor binding(GO:0031800)
0.1 1.8 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 1.0 GO:0044548 S100 protein binding(GO:0044548)
0.1 0.4 GO:0045545 syndecan binding(GO:0045545)
0.1 0.7 GO:0070569 uridylyltransferase activity(GO:0070569)
0.1 0.4 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.1 0.2 GO:2001069 glycogen binding(GO:2001069)
0.1 1.4 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 2.5 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 1.3 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 0.9 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.1 0.7 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 0.7 GO:0051378 G-protein coupled serotonin receptor activity(GO:0004993) serotonin binding(GO:0051378)
0.1 1.1 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 0.4 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.1 4.1 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.1 0.3 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.1 2.6 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.5 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.0 0.4 GO:0019966 interleukin-1 binding(GO:0019966)
0.0 1.3 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.4 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.6 GO:0005522 profilin binding(GO:0005522)
0.0 0.7 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.1 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.0 0.7 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 1.1 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.7 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.2 GO:0034432 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.0 0.1 GO:0098809 nitrite reductase activity(GO:0098809)
0.0 0.8 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.5 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.1 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 0.5 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 1.0 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 1.9 GO:0016836 hydro-lyase activity(GO:0016836)
0.0 0.7 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.5 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.8 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.1 GO:0000405 bubble DNA binding(GO:0000405)
0.0 0.2 GO:0070700 BMP receptor binding(GO:0070700)
0.0 4.1 GO:0052689 carboxylic ester hydrolase activity(GO:0052689)
0.0 1.1 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.1 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.0 1.4 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.4 GO:0008329 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0 0.5 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 1.4 GO:0008146 sulfotransferase activity(GO:0008146)
0.0 0.5 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.0 2.6 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.2 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.3 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.3 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.2 GO:0052813 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 0.2 GO:0071253 connexin binding(GO:0071253)
0.0 0.6 GO:0071837 HMG box domain binding(GO:0071837)
0.0 1.3 GO:0051287 NAD binding(GO:0051287)
0.0 0.7 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 0.8 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.7 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 1.1 GO:0061733 peptide-lysine-N-acetyltransferase activity(GO:0061733)
0.0 0.2 GO:0004579 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.5 GO:0017046 peptide hormone binding(GO:0017046)
0.0 0.2 GO:0050780 dopamine receptor binding(GO:0050780)
0.0 0.4 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.1 GO:0043262 adenosine-diphosphatase activity(GO:0043262)
0.0 0.5 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 1.4 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.0 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.2 2.9 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.1 2.5 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 6.6 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 1.3 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.1 0.8 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.1 1.4 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 2.8 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.1 0.9 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.1 4.0 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.1 1.0 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.1 2.2 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 1.3 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.1 0.4 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.1 2.1 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.7 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 1.5 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 7.5 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 2.7 PID ENDOTHELIN PATHWAY Endothelins
0.0 1.5 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.6 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 1.5 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 0.7 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 2.0 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 1.4 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.6 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.4 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 0.5 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.6 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 2.8 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.8 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.2 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.3 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.2 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.3 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.8 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 1.5 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.4 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.6 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.1 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.4 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.4 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.8 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.4 PID TNF PATHWAY TNF receptor signaling pathway
0.0 0.2 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.7 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.1 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.4 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 0.6 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.8 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 1.9 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 2.9 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 1.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 1.8 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.1 3.5 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.1 5.2 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 2.3 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 1.3 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 1.3 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 4.0 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 1.6 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.1 0.6 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.1 1.4 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.1 1.5 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.1 3.0 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 0.7 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.1 0.7 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.1 0.5 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1 0.8 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 1.0 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.1 7.2 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.4 REACTOME OPSINS Genes involved in Opsins
0.0 1.7 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 1.4 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 1.8 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.9 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 1.6 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 1.0 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.2 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 0.5 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 1.6 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.9 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.7 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 1.1 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.6 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 1.1 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 1.1 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.6 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.5 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.9 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 1.2 REACTOME SPHINGOLIPID METABOLISM Genes involved in Sphingolipid metabolism
0.0 2.6 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.0 3.3 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 4.9 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.4 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.0 0.4 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 0.3 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.5 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.2 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.3 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 1.4 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.4 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.6 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.8 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.4 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.1 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.6 REACTOME AMYLOIDS Genes involved in Amyloids