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12D miR HR13_24

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Results for Nfatc1

Z-value: 0.90

Motif logo

Transcription factors associated with Nfatc1

Gene Symbol Gene ID Gene Info
ENSMUSG00000033016.9 nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nfatc1mm10_v2_chr18_-_80708115_807081800.643.4e-02Click!

Activity profile of Nfatc1 motif

Sorted Z-values of Nfatc1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_142679533 1.61 ENSMUST00000162317.1
ENSMUST00000125933.1
ENSMUST00000105931.1
ENSMUST00000105930.1
ENSMUST00000105933.1
ENSMUST00000105932.1
ENSMUST00000000220.2
insulin II
chr18_+_37020097 1.37 ENSMUST00000047614.1
protocadherin alpha 2
chr18_-_80713062 1.21 ENSMUST00000170905.1
ENSMUST00000078049.4
nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1
chr3_+_106486009 1.17 ENSMUST00000183271.1
ENSMUST00000061206.3
DENN/MADD domain containing 2D
chr4_-_11386679 1.14 ENSMUST00000043781.7
ENSMUST00000108310.1
epithelial splicing regulatory protein 1
chr4_-_11386757 1.14 ENSMUST00000108313.1
ENSMUST00000108311.2
epithelial splicing regulatory protein 1
chr19_+_52264323 1.11 ENSMUST00000039652.4
insulin I
chrX_+_164438039 1.00 ENSMUST00000033755.5
ankyrin repeat and SOCS box-containing 11
chr11_-_31824463 0.96 ENSMUST00000129425.1
ENSMUST00000126265.1
RIKEN cDNA D630024D03 gene
chr11_-_31824518 0.96 ENSMUST00000134944.1
RIKEN cDNA D630024D03 gene
chr10_+_115817247 0.92 ENSMUST00000035563.7
ENSMUST00000080630.3
ENSMUST00000179196.1
tetraspanin 8
chr3_+_146121655 0.89 ENSMUST00000039450.4
mucolipin 3
chr19_+_22692613 0.89 ENSMUST00000099564.2
ENSMUST00000099566.3
transient receptor potential cation channel, subfamily M, member 3
chr14_+_75242287 0.86 ENSMUST00000022576.8
carboxypeptidase B2 (plasma)
chr2_-_103303179 0.81 ENSMUST00000090475.3
ets homologous factor
chr4_-_11386394 0.81 ENSMUST00000155519.1
epithelial splicing regulatory protein 1
chrX_+_164162167 0.81 ENSMUST00000131543.1
angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
chr2_-_103303158 0.78 ENSMUST00000111176.2
ets homologous factor
chr1_-_60043087 0.75 ENSMUST00000027172.6
islet cell autoantigen 1-like
chr4_-_126325641 0.71 ENSMUST00000131113.1
tektin 2
chrX_+_143664290 0.70 ENSMUST00000112868.1
p21 protein (Cdc42/Rac)-activated kinase 3
chr17_+_52602700 0.67 ENSMUST00000039366.10
potassium voltage-gated channel, subfamily H (eag-related), member 8
chrX_+_143664365 0.66 ENSMUST00000126592.1
ENSMUST00000156449.1
ENSMUST00000155215.1
ENSMUST00000112865.1
p21 protein (Cdc42/Rac)-activated kinase 3
chr8_+_106510853 0.66 ENSMUST00000080797.6
cadherin 3
chr10_+_116986314 0.65 ENSMUST00000020378.4
bestrophin 3
chr4_+_102589687 0.64 ENSMUST00000097949.4
ENSMUST00000106901.1
phosphodiesterase 4B, cAMP specific
chr4_+_134864536 0.64 ENSMUST00000030627.7
Rh blood group, D antigen
chr4_-_49593875 0.63 ENSMUST00000151542.1
transmembrane protein 246
chr16_-_22161450 0.63 ENSMUST00000115379.1
insulin-like growth factor 2 mRNA binding protein 2
chr3_-_129755305 0.62 ENSMUST00000029653.2
epidermal growth factor
chr11_-_58534825 0.61 ENSMUST00000170009.1
olfactory receptor 330
chr9_-_121792478 0.59 ENSMUST00000035110.4
hedgehog acyltransferase-like
chr9_+_100643755 0.59 ENSMUST00000133388.1
stromal antigen 1
chr18_+_36559972 0.59 ENSMUST00000134146.1
ankyrin repeat and KH domain containing 1
chr9_-_96862903 0.59 ENSMUST00000121077.1
ENSMUST00000124923.1
acid phosphatase-like 2
chr15_-_34356421 0.59 ENSMUST00000179647.1
RIKEN cDNA 9430069I07 gene
chr7_+_75643223 0.58 ENSMUST00000137959.1
A kinase (PRKA) anchor protein 13
chr5_-_88527841 0.57 ENSMUST00000087033.3
immunoglobulin joining chain
chr1_-_156204998 0.57 ENSMUST00000015628.3
family with sequence similarity 163, member A
chr9_+_107399858 0.57 ENSMUST00000085092.5
ENSMUST00000164988.2
calcium channel, voltage-dependent, alpha 2/delta subunit 2
chr14_-_16575456 0.57 ENSMUST00000063750.6
retinoic acid receptor, beta
chr11_-_11627824 0.55 ENSMUST00000081896.4
RIKEN cDNA 4930512M02 gene
chr7_-_30821139 0.54 ENSMUST00000163504.1
free fatty acid receptor 2
chr10_+_112172540 0.54 ENSMUST00000132994.1
calcyphosphine 2
chr1_-_120505084 0.54 ENSMUST00000027639.1
macrophage receptor with collagenous structure
chr19_+_58670358 0.53 ENSMUST00000057270.7
pancreatic lipase
chr4_-_126325672 0.52 ENSMUST00000102616.1
tektin 2
chr4_+_143349757 0.52 ENSMUST00000052458.2
leucine rich repeat containing 38
chr17_-_87282793 0.51 ENSMUST00000146560.2
RIKEN cDNA 4833418N02 gene
chr5_+_66968559 0.51 ENSMUST00000127184.1
LIM and calponin homology domains 1
chr10_-_19014549 0.50 ENSMUST00000146388.1
tumor necrosis factor, alpha-induced protein 3
chr13_+_40859768 0.49 ENSMUST00000110191.2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme
chr11_+_118433826 0.49 ENSMUST00000106286.1
C1q and tumor necrosis factor related protein 1
chr11_+_82045705 0.49 ENSMUST00000021011.2
chemokine (C-C motif) ligand 7
chr1_+_150100093 0.48 ENSMUST00000035065.7
prostaglandin-endoperoxide synthase 2
chrX_+_159627534 0.48 ENSMUST00000073094.3
SH3-domain kinase binding protein 1
chr1_-_127840290 0.47 ENSMUST00000061512.2
mitogen-activated protein kinase kinase kinase 19
chr3_-_59635733 0.46 ENSMUST00000177879.1
predicted gene 5709
chr5_+_66968961 0.46 ENSMUST00000132991.1
LIM and calponin homology domains 1
chr4_-_42168603 0.44 ENSMUST00000098121.3
predicted gene 13305
chr17_+_34204080 0.44 ENSMUST00000138491.1
transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
chr13_-_99900645 0.44 ENSMUST00000022150.6
CART prepropeptide
chr12_+_58211772 0.44 ENSMUST00000110671.2
ENSMUST00000044299.2
somatostatin receptor 1
chr7_+_43562256 0.43 ENSMUST00000107972.1
zinc finger protein 658
chr6_-_59426279 0.43 ENSMUST00000051065.4
GPRIN family member 3
chrX_+_103422010 0.42 ENSMUST00000182089.1
predicted gene, 26992
chr14_+_118787894 0.42 ENSMUST00000047761.6
ENSMUST00000071546.7
claudin 10
chr18_+_74442551 0.41 ENSMUST00000121875.1
myosin VB
chr18_+_74442500 0.41 ENSMUST00000074157.6
myosin VB
chr4_-_141825997 0.41 ENSMUST00000102481.3
chymotrypsin-like elastase family, member 2A
chr9_+_107400043 0.41 ENSMUST00000166799.1
ENSMUST00000170737.1
calcium channel, voltage-dependent, alpha 2/delta subunit 2
chr7_-_45510400 0.40 ENSMUST00000033096.7
nucleobindin 1
chr9_-_75597643 0.40 ENSMUST00000164100.1
tropomodulin 2
chr16_-_45492962 0.40 ENSMUST00000114585.2
predicted gene 609
chr2_+_35282380 0.40 ENSMUST00000028239.6
gelsolin
chr13_-_23761223 0.40 ENSMUST00000102964.2
histone cluster 1, H4a
chr17_-_87282771 0.40 ENSMUST00000161759.1
RIKEN cDNA 4833418N02 gene
chr7_+_134670667 0.39 ENSMUST00000084488.4
dedicator of cytokinesis 1
chr6_+_88724667 0.39 ENSMUST00000163271.1
monoglyceride lipase
chr9_-_20385090 0.39 ENSMUST00000068079.7
zinc finger protein 560
chr6_+_88724828 0.38 ENSMUST00000089449.2
monoglyceride lipase
chr10_-_95415283 0.38 ENSMUST00000119917.1
suppressor of cytokine signaling 2
chr11_-_96829959 0.38 ENSMUST00000081775.5
nuclear factor, erythroid derived 2,-like 1
chr12_+_55598917 0.38 ENSMUST00000051857.3
insulinoma-associated 2
chr10_+_19951055 0.37 ENSMUST00000152533.1
mitogen-activated protein kinase kinase kinase 5
chr6_-_41035501 0.36 ENSMUST00000031931.5
RIKEN cDNA 2210010C04 gene
chr17_+_34153072 0.36 ENSMUST00000114232.2
histocompatibility 2, class II, locus Mb1
chr18_+_37484955 0.36 ENSMUST00000053856.4
protocadherin beta 17
chr5_-_44099220 0.35 ENSMUST00000165909.1
prominin 1
chr4_-_56224520 0.35 ENSMUST00000128591.1
RIKEN cDNA 2310081O03 gene
chr10_+_127048235 0.35 ENSMUST00000165764.1
cytochrome P450, family 27, subfamily b, polypeptide 1
chr1_+_170214826 0.35 ENSMUST00000159201.1
ENSMUST00000055830.1
RIKEN cDNA 4930500M09 gene
chr5_-_105343929 0.34 ENSMUST00000183149.1
guanylate binding protein 11
chr6_+_41521782 0.34 ENSMUST00000070380.4
protease, serine, 2
chr8_+_105427634 0.34 ENSMUST00000067305.6
leucine rich repeat containing 36
chr9_+_100643448 0.34 ENSMUST00000146312.1
ENSMUST00000129269.1
stromal antigen 1
chr2_-_77170592 0.34 ENSMUST00000164114.2
ENSMUST00000049544.7
coiled-coil domain containing 141
chr9_+_100643605 0.34 ENSMUST00000041418.6
stromal antigen 1
chrX_+_72987339 0.33 ENSMUST00000164800.1
ENSMUST00000114546.2
zinc finger protein 185
chr17_-_23844155 0.32 ENSMUST00000122936.1
ENSMUST00000024926.7
ENSMUST00000151797.1
protease, serine, 41
chr7_+_51880312 0.31 ENSMUST00000145049.1
growth arrest specific 2
chr11_-_100207507 0.31 ENSMUST00000007272.7
keratin 14
chrX_-_48454152 0.30 ENSMUST00000114958.1
E74-like factor 4 (ets domain transcription factor)
chr14_+_22019712 0.30 ENSMUST00000075639.4
ENSMUST00000161249.1
RIKEN cDNA 1700112E06 gene
chr18_-_3337614 0.30 ENSMUST00000150235.1
ENSMUST00000154470.1
cAMP responsive element modulator
chr14_-_54870913 0.29 ENSMUST00000146642.1
homeodomain leucine zipper-encoding gene
chr15_+_98708187 0.29 ENSMUST00000003444.4
coiled-coil domain containing 65
chr5_+_17574268 0.29 ENSMUST00000030568.7
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr13_+_23738804 0.29 ENSMUST00000040914.1
histone cluster 1, H1c
chr19_-_5845471 0.29 ENSMUST00000174287.1
ENSMUST00000173672.1
nuclear paraspeckle assembly transcript 1 (non-protein coding)
chr4_+_116596672 0.29 ENSMUST00000051869.7
coiled-coil domain containing 17
chr10_-_93310963 0.29 ENSMUST00000151153.1
ELK3, member of ETS oncogene family
chr19_-_57118897 0.29 ENSMUST00000111526.1
actin-binding LIM protein 1
chr4_+_97777780 0.28 ENSMUST00000107062.2
ENSMUST00000052018.5
ENSMUST00000107057.1
nuclear factor I/A
chr18_+_36560581 0.28 ENSMUST00000155329.2
ankyrin repeat and KH domain containing 1
chr7_+_99535652 0.28 ENSMUST00000032995.8
ENSMUST00000162404.1
arrestin, beta 1
chr14_+_25842174 0.28 ENSMUST00000112364.1
annexin A11
chr16_+_21423118 0.28 ENSMUST00000096191.4
ENSMUST00000096192.5
ENSMUST00000115397.1
ENSMUST00000118923.1
ENSMUST00000122235.1
ENSMUST00000117598.1
ENSMUST00000139473.1
vacuolar protein sorting 8 homolog (S. cerevisiae)
chr10_-_54075730 0.28 ENSMUST00000105469.1
ENSMUST00000003843.8
mannosidase 1, alpha
chr7_+_81523531 0.28 ENSMUST00000181903.1
RIKEN cDNA 2900076A07 gene
chr17_+_21423227 0.28 ENSMUST00000165230.1
ENSMUST00000007884.8
ENSMUST00000167749.1
zinc finger protein 54
chr7_+_99535439 0.27 ENSMUST00000098266.2
ENSMUST00000179755.1
arrestin, beta 1
chr1_+_88095054 0.26 ENSMUST00000150634.1
ENSMUST00000058237.7
UDP glucuronosyltransferase 1 family, polypeptide A7C
chr1_-_121328024 0.26 ENSMUST00000003818.7
insulin induced gene 2
chr16_-_3718105 0.26 ENSMUST00000023180.7
ENSMUST00000100222.2
Mediterranean fever
chrX_+_159627265 0.26 ENSMUST00000112456.2
SH3-domain kinase binding protein 1
chr15_-_41869703 0.26 ENSMUST00000054742.5
actin-binding Rho activating protein
chr6_+_91684061 0.25 ENSMUST00000032185.7
solute carrier family 6 (neurotransmitter transporter, taurine), member 6
chr18_+_37742088 0.24 ENSMUST00000003599.6
protocadherin gamma subfamily A, 9
chr3_-_117360876 0.24 ENSMUST00000061071.8
DNA segment, Chr 3, Brigham & Women's Genetics 0562 expressed
chr17_+_8988348 0.24 ENSMUST00000151609.1
RIKEN cDNA 1700010I14 gene
chr9_-_124424154 0.24 ENSMUST00000180270.1
protein phosphatase 2 (formerly 2A), regulatory subunit B'', delta
chr19_-_37176055 0.24 ENSMUST00000142973.1
ENSMUST00000154376.1
cytoplasmic polyadenylation element binding protein 3
chr18_-_15403680 0.23 ENSMUST00000079081.6
aquaporin 4
chr14_+_79515618 0.23 ENSMUST00000110835.1
E74-like factor 1
chr11_-_99493112 0.23 ENSMUST00000006969.7
keratin 23
chr1_-_170927567 0.23 ENSMUST00000046322.7
ENSMUST00000159171.1
Fc receptor-like A
chr10_-_95415484 0.23 ENSMUST00000172070.1
ENSMUST00000150432.1
suppressor of cytokine signaling 2
chr8_-_25038875 0.23 ENSMUST00000084031.4
HtrA serine peptidase 4
chr6_+_30723541 0.23 ENSMUST00000115127.1
mesoderm specific transcript
chr1_+_180330470 0.22 ENSMUST00000070181.6
inositol 1,4,5-trisphosphate 3-kinase B
chr9_-_50528641 0.22 ENSMUST00000034570.5
6-pyruvoyl-tetrahydropterin synthase
chr4_-_82505707 0.22 ENSMUST00000107248.1
ENSMUST00000107247.1
nuclear factor I/B
chr14_+_25842146 0.22 ENSMUST00000022416.8
annexin A11
chrX_-_38635066 0.22 ENSMUST00000058265.7
C1GALT1-specific chaperone 1
chr11_-_100261021 0.22 ENSMUST00000080893.6
keratin 17
chr7_+_81523555 0.22 ENSMUST00000180385.1
ENSMUST00000180879.1
ENSMUST00000181164.1
ENSMUST00000181264.1
RIKEN cDNA 2900076A07 gene
chr3_+_5218546 0.22 ENSMUST00000026284.6
zinc finger homeodomain 4
chr1_+_87264345 0.21 ENSMUST00000118687.1
ENSMUST00000027472.6
EF hand domain containing 1
chr9_+_124102110 0.21 ENSMUST00000168841.1
ENSMUST00000055918.6
chemokine (C-C motif) receptor 2
chr11_+_62879449 0.21 ENSMUST00000014321.4
trans-golgi network vesicle protein 23B
chr15_-_100424092 0.21 ENSMUST00000154676.1
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr15_+_78926720 0.21 ENSMUST00000089377.5
lectin, galactose binding, soluble 1
chr7_+_30423266 0.21 ENSMUST00000046177.8
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, delta
chr3_+_14533788 0.20 ENSMUST00000108370.2
leucine rich repeat and coiled-coil domain containing 1
chr9_-_40455670 0.20 ENSMUST00000165104.1
ENSMUST00000045682.5
GRAM domain containing 1B
chr7_+_90426312 0.20 ENSMUST00000061391.7
coiled-coil domain containing 89
chr7_+_88430257 0.20 ENSMUST00000107256.2
RAB38, member of RAS oncogene family
chr8_-_69373914 0.20 ENSMUST00000095282.1
predicted gene 10311
chr6_-_31218421 0.20 ENSMUST00000115107.1
cDNA sequence AB041803
chr10_-_93311073 0.20 ENSMUST00000008542.5
ELK3, member of ETS oncogene family
chr13_-_105054895 0.20 ENSMUST00000063551.5
regulator of G-protein signalling 7 binding protein
chr1_-_36557517 0.19 ENSMUST00000114990.1
ENSMUST00000128104.1
ENSMUST00000027295.4
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
chr3_+_106113229 0.19 ENSMUST00000079132.5
ENSMUST00000139086.1
chitinase, acidic
chrX_+_161717498 0.19 ENSMUST00000061514.7
retinoic acid induced 2
chr3_+_79884931 0.19 ENSMUST00000135021.1
family with sequence similarity 198, member B
chr8_+_34115030 0.19 ENSMUST00000095345.3
membrane bound O-acyltransferase domain containing 4
chr7_+_5350542 0.19 ENSMUST00000056639.6
predicted gene 5065
chr1_+_88211956 0.19 ENSMUST00000073049.6
UDP glucuronosyltransferase 1 family, polypeptide A1
chr13_-_67637776 0.18 ENSMUST00000012314.8
RIKEN cDNA A530054K11 gene
chr1_+_4808237 0.18 ENSMUST00000131119.1
lysophospholipase 1
chr7_+_122965636 0.18 ENSMUST00000148880.1
retinoblastoma binding protein 6
chr3_-_148989316 0.18 ENSMUST00000098518.2
latrophilin 2
chr2_+_93452796 0.18 ENSMUST00000099693.2
ENSMUST00000162565.1
ENSMUST00000163052.1
predicted gene 10804
chr3_-_116711820 0.18 ENSMUST00000153108.1
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member 3
chr3_+_96696379 0.18 ENSMUST00000107076.3
protein inhibitor of activated STAT 3
chr19_+_46003468 0.18 ENSMUST00000099393.2
Hermansky-Pudlak syndrome 6
chr4_+_102760294 0.18 ENSMUST00000072481.5
ENSMUST00000156596.1
ENSMUST00000080728.6
ENSMUST00000106882.2
SH3-domain GRB2-like (endophilin) interacting protein 1
chr1_+_177444653 0.18 ENSMUST00000094276.3
zinc finger and BTB domain containing 18
chr14_-_21052120 0.17 ENSMUST00000130370.1
ENSMUST00000022371.3
adaptor-related protein complex 3, mu 1 subunit
chr3_+_14533817 0.17 ENSMUST00000169079.1
ENSMUST00000091325.3
leucine rich repeat and coiled-coil domain containing 1
chr14_+_51984857 0.17 ENSMUST00000100639.4
ENSMUST00000182909.1
ENSMUST00000182760.1
ENSMUST00000182061.1
ENSMUST00000182193.1
Rho guanine nucleotide exchange factor (GEF) 40
chr9_+_38752796 0.17 ENSMUST00000074740.2
olfactory receptor 920
chr13_-_67724264 0.17 ENSMUST00000127979.1
ENSMUST00000130891.1
zinc finger protein 71, related sequence
chr17_+_8988333 0.17 ENSMUST00000024650.5
RIKEN cDNA 1700010I14 gene
chr2_+_30237680 0.17 ENSMUST00000113654.1
ENSMUST00000095078.2
leucine rich repeat containing 8A
chr5_+_104508338 0.16 ENSMUST00000096452.4
cDNA sequence BC005561
chr3_-_88334482 0.16 ENSMUST00000001456.4
transmembrane protein 79
chr8_+_45627946 0.16 ENSMUST00000145458.1
sorbin and SH3 domain containing 2
chr1_+_60908993 0.16 ENSMUST00000027164.2
cytotoxic T-lymphocyte-associated protein 4
chr5_-_103629279 0.16 ENSMUST00000031263.1
solute carrier family 10 (sodium/bile acid cotransporter family), member 6
chr15_-_9748777 0.16 ENSMUST00000159368.1
ENSMUST00000159093.1
ENSMUST00000162780.1
ENSMUST00000160236.1
ENSMUST00000041840.7
sperm flagellar 2
chr14_+_120749352 0.16 ENSMUST00000138893.2
predicted gene, 17613
chr4_+_150087365 0.16 ENSMUST00000094451.3
G protein-coupled receptor 157
chrX_-_133688978 0.16 ENSMUST00000149154.1
ENSMUST00000167944.1
protocadherin 19
chr12_+_36090379 0.16 ENSMUST00000071825.5
predicted gene 5434
chr19_+_46623387 0.16 ENSMUST00000111855.4
WW domain binding protein 1 like
chrX_-_9469288 0.16 ENSMUST00000015484.3
cytochrome b-245, beta polypeptide
chr14_+_55560010 0.16 ENSMUST00000147981.1
ENSMUST00000133256.1
DDB1 and CUL4 associated factor 11
chr4_-_12087912 0.16 ENSMUST00000050686.3
transmembrane protein 67

Network of associatons between targets according to the STRING database.

First level regulatory network of Nfatc1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0033861 negative regulation of NAD(P)H oxidase activity(GO:0033861) neuron projection maintenance(GO:1990535)
0.4 1.2 GO:0060854 patterning of lymph vessels(GO:0060854)
0.3 0.9 GO:0003331 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.2 0.7 GO:0051794 regulation of catagen(GO:0051794)
0.2 0.6 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.2 0.8 GO:0015827 angiotensin-mediated drinking behavior(GO:0003051) aromatic amino acid transport(GO:0015801) tryptophan transport(GO:0015827)
0.2 0.5 GO:0002879 cell surface pattern recognition receptor signaling pathway(GO:0002752) positive regulation of acute inflammatory response to non-antigenic stimulus(GO:0002879)
0.2 0.5 GO:0034148 regulation of granuloma formation(GO:0002631) negative regulation of granuloma formation(GO:0002632) regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) tolerance induction to lipopolysaccharide(GO:0072573)
0.2 0.5 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.1 0.4 GO:0046968 positive regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002591) peptide antigen transport(GO:0046968)
0.1 0.4 GO:0070093 negative regulation of glucagon secretion(GO:0070093)
0.1 0.8 GO:0032439 endosome localization(GO:0032439)
0.1 0.4 GO:1903903 positive regulation of keratinocyte apoptotic process(GO:1902174) regulation of establishment of T cell polarity(GO:1903903)
0.1 0.6 GO:0007262 STAT protein import into nucleus(GO:0007262)
0.1 0.4 GO:2000458 immune complex clearance by monocytes and macrophages(GO:0002436) astrocyte chemotaxis(GO:0035700) regulation of immune complex clearance by monocytes and macrophages(GO:0090264) positive regulation of immune complex clearance by monocytes and macrophages(GO:0090265) negative regulation of eosinophil activation(GO:1902567) positive regulation of CD8-positive, alpha-beta T cell extravasation(GO:2000451) regulation of astrocyte chemotaxis(GO:2000458)
0.1 1.0 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.1 0.6 GO:1903059 regulation of protein lipidation(GO:1903059)
0.1 0.4 GO:0072139 glomerular parietal epithelial cell differentiation(GO:0072139)
0.1 0.7 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.1 0.6 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.1 0.8 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.1 0.3 GO:0070268 cornification(GO:0070268)
0.1 0.3 GO:0046271 coumarin metabolic process(GO:0009804) phenylpropanoid catabolic process(GO:0046271)
0.1 0.3 GO:0010980 regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.1 1.2 GO:0036159 inner dynein arm assembly(GO:0036159)
0.1 0.5 GO:0036438 maintenance of lens transparency(GO:0036438)
0.1 3.4 GO:0060445 branching involved in salivary gland morphogenesis(GO:0060445)
0.1 0.6 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.1 0.2 GO:1900248 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.1 0.6 GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.1 0.3 GO:0071608 macrophage inflammatory protein-1 alpha production(GO:0071608)
0.1 0.3 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.1 0.2 GO:0070295 renal water absorption(GO:0070295)
0.1 1.4 GO:0010763 positive regulation of fibroblast migration(GO:0010763)
0.1 0.1 GO:0002884 negative regulation of hypersensitivity(GO:0002884)
0.1 0.3 GO:0098734 protein depalmitoylation(GO:0002084) negative regulation of Golgi to plasma membrane protein transport(GO:0042997) negative regulation of establishment of protein localization to plasma membrane(GO:0090005) macromolecule depalmitoylation(GO:0098734)
0.1 0.2 GO:0033030 negative regulation of neutrophil apoptotic process(GO:0033030)
0.1 0.2 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.1 0.5 GO:2000860 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.1 0.7 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 0.2 GO:0006533 aspartate catabolic process(GO:0006533)
0.1 0.4 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.2 GO:0060155 platelet dense granule organization(GO:0060155)
0.0 0.1 GO:0090481 pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.0 0.1 GO:0045626 negative regulation of T-helper 1 cell differentiation(GO:0045626)
0.0 0.1 GO:0033377 protein localization to secretory granule(GO:0033366) protein localization to mast cell secretory granule(GO:0033367) protease localization to mast cell secretory granule(GO:0033368) maintenance of protein location in mast cell secretory granule(GO:0033370) T cell secretory granule organization(GO:0033371) maintenance of protease location in mast cell secretory granule(GO:0033373) protein localization to T cell secretory granule(GO:0033374) protease localization to T cell secretory granule(GO:0033375) maintenance of protein location in T cell secretory granule(GO:0033377) maintenance of protease location in T cell secretory granule(GO:0033379) granzyme B localization to T cell secretory granule(GO:0033380) maintenance of granzyme B location in T cell secretory granule(GO:0033382)
0.0 0.2 GO:0015676 vanadium ion transport(GO:0015676) lead ion transport(GO:0015692)
0.0 0.2 GO:0015788 UDP-N-acetylglucosamine transport(GO:0015788)
0.0 0.1 GO:0003345 proepicardium cell migration involved in pericardium morphogenesis(GO:0003345)
0.0 0.3 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.1 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.0 0.5 GO:0071361 cellular response to ethanol(GO:0071361)
0.0 0.5 GO:1903818 positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.0 0.3 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.5 GO:0061365 intestinal cholesterol absorption(GO:0030299) positive regulation of triglyceride lipase activity(GO:0061365)
0.0 0.2 GO:0002036 regulation of L-glutamate transport(GO:0002036)
0.0 0.2 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
0.0 0.1 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.0 0.1 GO:0032474 otolith morphogenesis(GO:0032474)
0.0 0.1 GO:0009253 peptidoglycan metabolic process(GO:0000270) natural killer cell differentiation involved in immune response(GO:0002325) peptidoglycan catabolic process(GO:0009253) negative regulation of natural killer cell differentiation(GO:0032824) regulation of natural killer cell differentiation involved in immune response(GO:0032826) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827)
0.0 0.2 GO:0002317 plasma cell differentiation(GO:0002317)
0.0 0.1 GO:0035522 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.0 0.7 GO:0071378 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.0 0.3 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.0 0.4 GO:0061436 establishment of skin barrier(GO:0061436)
0.0 0.1 GO:1904925 positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.0 0.4 GO:1902170 cellular response to reactive nitrogen species(GO:1902170)
0.0 0.1 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.0 0.2 GO:0001866 NK T cell proliferation(GO:0001866)
0.0 0.2 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.2 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729)
0.0 0.5 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.0 0.1 GO:0060084 synaptic transmission involved in micturition(GO:0060084)
0.0 0.4 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.0 0.1 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 0.2 GO:0060019 radial glial cell differentiation(GO:0060019)
0.0 0.2 GO:0070245 positive regulation of thymocyte apoptotic process(GO:0070245)
0.0 0.5 GO:0032506 cytokinetic process(GO:0032506)
0.0 0.3 GO:0031000 response to caffeine(GO:0031000)
0.0 0.2 GO:0042559 pteridine-containing compound biosynthetic process(GO:0042559)
0.0 0.2 GO:0051798 positive regulation of hair follicle development(GO:0051798)
0.0 0.3 GO:0060363 cranial suture morphogenesis(GO:0060363)
0.0 0.2 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.1 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.0 0.1 GO:0060809 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302) mesodermal to mesenchymal transition involved in gastrulation(GO:0060809)
0.0 0.3 GO:0072189 ureter development(GO:0072189)
0.0 0.1 GO:1903976 negative regulation of glial cell migration(GO:1903976)
0.0 0.9 GO:0030195 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.0 0.1 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.0 0.4 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.0 0.2 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.0 0.1 GO:0032227 negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.0 0.1 GO:0061056 sclerotome development(GO:0061056)
0.0 0.2 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.1 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.0 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 0.1 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.1 GO:0036309 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371) regulation of SA node cell action potential(GO:0098907)
0.0 0.1 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 0.1 GO:0015791 polyol transport(GO:0015791)
0.0 0.8 GO:0042491 auditory receptor cell differentiation(GO:0042491)
0.0 0.1 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.0 GO:0021550 medulla oblongata development(GO:0021550) hindbrain tangential cell migration(GO:0021934) sensory system development(GO:0048880)
0.0 0.1 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.2 GO:0010826 negative regulation of centrosome duplication(GO:0010826) negative regulation of centrosome cycle(GO:0046606)
0.0 0.3 GO:0030575 nuclear body organization(GO:0030575)
0.0 0.0 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.0 0.1 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0 0.2 GO:0002329 pre-B cell differentiation(GO:0002329)
0.0 0.0 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.0 0.1 GO:0072318 clathrin coat disassembly(GO:0072318)
0.0 0.1 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.0 GO:1990743 protein sialylation(GO:1990743)
0.0 0.2 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.1 GO:0018916 nitrobenzene metabolic process(GO:0018916)
0.0 0.0 GO:1903542 negative regulation of exosomal secretion(GO:1903542)
0.0 0.2 GO:0007288 sperm axoneme assembly(GO:0007288)
0.0 0.3 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.1 GO:0007341 penetration of zona pellucida(GO:0007341)
0.0 0.4 GO:0051642 centrosome localization(GO:0051642)
0.0 0.0 GO:0032468 cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) manganese ion homeostasis(GO:0055071)
0.0 0.0 GO:1900045 negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0031084 BLOC-2 complex(GO:0031084)
0.1 0.4 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.1 0.4 GO:0071914 prominosome(GO:0071914)
0.1 1.6 GO:0005732 small nucleolar ribonucleoprotein complex(GO:0005732)
0.1 0.4 GO:0042825 TAP complex(GO:0042825)
0.1 0.4 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.1 0.7 GO:0045179 apical cortex(GO:0045179)
0.0 0.2 GO:0070826 paraferritin complex(GO:0070826)
0.0 0.5 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0 0.4 GO:0030478 actin cap(GO:0030478)
0.0 0.1 GO:0070195 growth hormone receptor complex(GO:0070195)
0.0 0.3 GO:0033263 CORVET complex(GO:0033263)
0.0 0.8 GO:0043196 varicosity(GO:0043196)
0.0 0.2 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.3 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 1.7 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.4 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.2 GO:0042382 paraspeckles(GO:0042382)
0.0 0.1 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.0 0.3 GO:0036038 MKS complex(GO:0036038)
0.0 0.3 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.3 GO:0031209 SCAR complex(GO:0031209)
0.0 0.3 GO:0031143 pseudopodium(GO:0031143)
0.0 0.2 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.2 GO:0002177 manchette(GO:0002177)
0.0 0.1 GO:0042629 mast cell granule(GO:0042629)
0.0 0.2 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.2 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.4 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 0.4 GO:0045095 keratin filament(GO:0045095)
0.0 0.4 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 1.2 GO:0036126 sperm flagellum(GO:0036126)
0.0 0.2 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.2 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.6 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.2 GO:1904115 axon cytoplasm(GO:1904115)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.2 0.6 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.1 0.5 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1 0.6 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.1 0.5 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.1 0.4 GO:0035717 chemokine (C-C motif) ligand 7 binding(GO:0035717)
0.1 0.5 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 0.8 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.1 0.7 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.1 0.4 GO:0046980 peptide antigen-transporting ATPase activity(GO:0015433) tapasin binding(GO:0046980)
0.1 0.4 GO:0004994 somatostatin receptor activity(GO:0004994)
0.1 0.2 GO:0030977 taurine binding(GO:0030977)
0.1 0.2 GO:0045159 myosin II binding(GO:0045159)
0.1 0.2 GO:0048030 disaccharide binding(GO:0048030)
0.1 0.2 GO:0035651 AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651)
0.1 0.6 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 1.4 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.1 0.5 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.1 0.3 GO:1990254 keratin filament binding(GO:1990254)
0.1 0.6 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 0.8 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.5 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.2 GO:0015100 cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.0 1.3 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.1 GO:0004903 growth hormone receptor activity(GO:0004903)
0.0 0.2 GO:0003884 D-amino-acid oxidase activity(GO:0003884)
0.0 0.5 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.1 GO:0016019 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745) peptidoglycan receptor activity(GO:0016019)
0.0 0.2 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.0 0.3 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.2 GO:0015288 porin activity(GO:0015288)
0.0 0.2 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 0.9 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.3 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 1.1 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.2 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.6 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.6 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.6 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.0 0.1 GO:0046923 ER retention sequence binding(GO:0046923)
0.0 1.2 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.1 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.0 0.2 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.2 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.4 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.6 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.2 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.1 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211)
0.0 0.2 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 1.0 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.7 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.3 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.4 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.5 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.4 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.0 0.1 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.1 GO:0031849 olfactory receptor binding(GO:0031849)
0.0 0.1 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.2 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.0 GO:0001962 alpha-1,3-galactosyltransferase activity(GO:0001962)
0.0 0.1 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.1 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0 0.1 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
0.0 0.1 GO:0008865 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.4 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 3.1 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 0.2 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.4 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 0.6 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.1 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.1 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.0 0.6 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.1 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.0 GO:0015410 manganese-transporting ATPase activity(GO:0015410)
0.0 0.1 GO:0031685 adenosine receptor binding(GO:0031685)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.2 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.6 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 1.4 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 1.2 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.3 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.4 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.4 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.0 1.0 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 0.7 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.6 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.1 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.4 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.6 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.6 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.1 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.8 PID REG GR PATHWAY Glucocorticoid receptor regulatory network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.8 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 1.4 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.7 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.7 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.7 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.4 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 1.7 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.7 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.3 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.6 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 0.3 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.7 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.6 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.7 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.4 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.2 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.2 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.5 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.2 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.3 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 0.1 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.2 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.1 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.4 REACTOME CELL CELL JUNCTION ORGANIZATION Genes involved in Cell-cell junction organization