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12D miR HR13_24

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Results for Nkx2-6

Z-value: 0.23

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Transcription factors associated with Nkx2-6

Gene Symbol Gene ID Gene Info
ENSMUSG00000044186.9 NK2 homeobox 6

Activity profile of Nkx2-6 motif

Sorted Z-values of Nkx2-6 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr15_-_78773452 0.32 ENSMUST00000018313.5
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr4_-_91399984 0.26 ENSMUST00000102799.3
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr2_-_119229885 0.25 ENSMUST00000076084.5
protein phosphatase 1, regulatory (inhibitor) subunit 14D
chr7_-_116237767 0.24 ENSMUST00000182834.1
pleckstrin homology domain containing, family A member 7
chr2_-_119229849 0.19 ENSMUST00000110820.2
protein phosphatase 1, regulatory (inhibitor) subunit 14D
chr5_+_110330697 0.15 ENSMUST00000112481.1
polymerase (DNA directed), epsilon
chr15_+_73723131 0.13 ENSMUST00000165541.1
ENSMUST00000167582.1
protein tyrosine phosphatase 4a3
chr4_-_109665249 0.11 ENSMUST00000063531.4
cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
chr17_-_45599603 0.08 ENSMUST00000171847.1
ENSMUST00000166633.1
ENSMUST00000169729.1
solute carrier family 29 (nucleoside transporters), member 1
chr2_+_3114220 0.08 ENSMUST00000072955.5
family with sequence similarity 171, member A1
chr7_-_116031047 0.08 ENSMUST00000106612.1
SRY-box containing gene 6
chr14_-_73049107 0.07 ENSMUST00000044664.4
ENSMUST00000169168.1
cysteinyl leukotriene receptor 2
chr6_+_70726430 0.05 ENSMUST00000103410.1
immunoglobulin kappa constant
chr3_+_62419668 0.05 ENSMUST00000161057.1
Rho guanine nucleotide exchange factor (GEF) 26
chr14_-_20269162 0.04 ENSMUST00000024155.7
potassium channel, subfamily K, member 16
chr4_+_139653538 0.02 ENSMUST00000030510.7
ENSMUST00000166773.1
taste receptor, type 1, member 2
chr5_-_90223923 0.02 ENSMUST00000118816.1
ENSMUST00000048363.7
cytochrome c oxidase assembly protein 18
chr2_-_147186389 0.01 ENSMUST00000109970.3
ENSMUST00000067075.5
NK2 homeobox 2
chr1_+_179961110 0.01 ENSMUST00000076687.5
ENSMUST00000097450.3
CDC42 binding protein kinase alpha
chr1_+_179960472 0.00 ENSMUST00000097453.2
ENSMUST00000111117.1
CDC42 binding protein kinase alpha
chr14_+_54360826 0.00 ENSMUST00000000985.5
oxidase assembly 1-like

Network of associatons between targets according to the STRING database.

First level regulatory network of Nkx2-6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0045004 DNA replication proofreading(GO:0045004)
0.0 0.2 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.3 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.1 GO:0015862 uridine transport(GO:0015862)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 0.2 GO:0005915 zonula adherens(GO:0005915)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.1 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 0.2 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.2 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.2 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER