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12D miR HR13_24

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Results for Arid3a

Z-value: 0.78

Motif logo

Transcription factors associated with Arid3a

Gene Symbol Gene ID Gene Info
ENSMUSG00000019564.6 AT rich interactive domain 3A (BRIGHT-like)

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Arid3amm10_v2_chr10_+_79927330_79927370-0.605.3e-02Click!

Activity profile of Arid3a motif

Sorted Z-values of Arid3a motif

Promoter Log-likelihood Transcript Gene Gene Info
chr13_-_3945349 3.17 ENSMUST00000058610.7
urocortin 3
chr1_-_158958367 3.07 ENSMUST00000159861.2
pappalysin 2
chr8_+_84415348 1.65 ENSMUST00000121390.1
ENSMUST00000122053.1
calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
chr4_+_58943575 1.13 ENSMUST00000107554.1
zinc finger with KRAB and SCAN domains 16
chr15_+_10314102 1.02 ENSMUST00000127467.1
prolactin receptor
chr15_+_100334929 0.99 ENSMUST00000075420.4
methyltransferase like 7A3
chr1_-_132139666 0.98 ENSMUST00000027697.5
cyclin-dependent kinase 18
chr1_-_132139605 0.92 ENSMUST00000112362.2
cyclin-dependent kinase 18
chr3_-_85741389 0.91 ENSMUST00000094148.4
family with sequence similarity 160, member A1
chr9_+_108392820 0.85 ENSMUST00000035234.4
RIKEN cDNA 1700102P08 gene
chr1_+_171113918 0.80 ENSMUST00000129651.1
ENSMUST00000151340.1
RIKEN cDNA 1700009P17 gene
chr7_+_140941550 0.77 ENSMUST00000079403.4
ATH1, acid trehalase-like 1 (yeast)
chr15_-_3583191 0.72 ENSMUST00000069451.4
growth hormone receptor
chr13_+_72632597 0.66 ENSMUST00000172353.1
Iroquois related homeobox 2 (Drosophila)
chr18_+_36939178 0.65 ENSMUST00000115662.2
protocadherin alpha 2
chr18_-_6241470 0.62 ENSMUST00000163210.1
kinesin family member 5B
chr11_+_58199556 0.62 ENSMUST00000035266.4
ENSMUST00000094169.4
ENSMUST00000168280.1
ENSMUST00000058704.8
interferon gamma induced GTPase
immunity-related GTPase family M member 2
chr15_-_3582596 0.60 ENSMUST00000161770.1
growth hormone receptor
chr7_+_51878967 0.60 ENSMUST00000051912.6
growth arrest specific 2
chr18_-_6241486 0.59 ENSMUST00000025083.7
kinesin family member 5B
chr17_-_78684262 0.58 ENSMUST00000145480.1
striatin, calmodulin binding protein
chr15_-_3583146 0.55 ENSMUST00000110698.2
growth hormone receptor
chr5_-_70842617 0.55 ENSMUST00000031119.1
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1
chr7_-_121981669 0.53 ENSMUST00000057576.7
component of oligomeric golgi complex 7
chr7_+_51879041 0.53 ENSMUST00000107591.2
growth arrest specific 2
chr6_+_145615757 0.51 ENSMUST00000087445.6
tubulin, alpha 3B
chr11_+_5520652 0.50 ENSMUST00000063084.9
X-box binding protein 1
chr17_-_47421873 0.49 ENSMUST00000073143.6
RIKEN cDNA 1700001C19 gene
chr11_+_117484368 0.49 ENSMUST00000092394.3
predicted gene 11733
chr4_-_147642496 0.47 ENSMUST00000133006.1
ENSMUST00000037565.7
ENSMUST00000105720.1
RIKEN cDNA 2610305D13 gene
chr18_+_32815383 0.43 ENSMUST00000025237.3
thymic stromal lymphopoietin
chr10_-_52194956 0.43 ENSMUST00000117992.2
Ros1 proto-oncogene
chrX_-_141474034 0.42 ENSMUST00000101205.2
collagen, type IV, alpha 6
chr15_+_83563571 0.41 ENSMUST00000047419.6
translocator protein
chr4_-_25281752 0.40 ENSMUST00000038705.7
UFM1 specific ligase 1
chr1_+_40429563 0.39 ENSMUST00000174335.1
interleukin 1 receptor-like 1
chr1_+_60181495 0.39 ENSMUST00000160834.1
neurobeachin like 1
chr13_-_92030897 0.38 ENSMUST00000149630.1
RAS protein-specific guanine nucleotide-releasing factor 2
chr11_+_87664274 0.36 ENSMUST00000092800.5
ring finger protein 43
chr11_+_83175186 0.34 ENSMUST00000000208.5
ENSMUST00000167596.1
schlafen 4
chr19_+_58728887 0.33 ENSMUST00000048644.5
pancreatic lipase related protein 1
chr6_-_89940507 0.33 ENSMUST00000054202.3
vomeronasal 1 receptor 45
chr5_-_149015806 0.33 ENSMUST00000133243.1
predicted gene 15411
chr2_+_164460945 0.32 ENSMUST00000072452.4
SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)
chr16_-_10395476 0.31 ENSMUST00000043415.6
tektin 5
chr11_-_99351086 0.30 ENSMUST00000017732.2
keratin 27
chr11_+_100319880 0.30 ENSMUST00000049385.7
eukaryotic translation initiation factor 1
chr17_+_36837123 0.27 ENSMUST00000179968.1
ENSMUST00000130367.1
ENSMUST00000130801.1
ENSMUST00000144182.1
ENSMUST00000123715.1
ENSMUST00000053434.8
tripartite motif-containing 26
chr4_+_65124174 0.26 ENSMUST00000084501.3
pregnancy-associated plasma protein A
chr2_+_176807362 0.26 ENSMUST00000179435.1
predicted gene 14295
chr13_-_55415166 0.26 ENSMUST00000054146.3
profilin 3
chr8_+_45069137 0.26 ENSMUST00000067984.7
melatonin receptor 1A
chr7_+_45621805 0.25 ENSMUST00000033100.4
izumo sperm-egg fusion 1
chr1_+_155158703 0.25 ENSMUST00000027743.7
syntaxin 6
chr9_+_54538984 0.24 ENSMUST00000060242.5
ENSMUST00000118413.1
SH2 domain containing 7
chr3_+_95282897 0.24 ENSMUST00000039537.7
ENSMUST00000107187.2
family with sequence similarity 63, member A
chr2_-_126500631 0.23 ENSMUST00000129187.1
ATPase, class I, type 8B, member 4
chr16_-_4679703 0.22 ENSMUST00000038552.6
ENSMUST00000090480.4
coronin 7
chr10_-_127751707 0.21 ENSMUST00000079692.5
G protein-coupled receptor 182
chr8_+_95534078 0.20 ENSMUST00000041569.3
coiled-coil domain containing 113
chr8_+_129133702 0.19 ENSMUST00000148621.1
RIKEN cDNA 1700008F21 gene
chr14_+_26894557 0.19 ENSMUST00000090337.4
ENSMUST00000165929.2
ankyrin repeat and SOCS box-containing 14
chr6_+_129350237 0.17 ENSMUST00000065289.4
C-type lectin domain family 12, member a
chr1_+_179961110 0.17 ENSMUST00000076687.5
ENSMUST00000097450.3
CDC42 binding protein kinase alpha
chr10_+_116966274 0.17 ENSMUST00000033651.3
RIKEN cDNA D630029K05 gene
chr4_-_108071327 0.16 ENSMUST00000106701.1
sterol carrier protein 2, liver
chrX_+_162901226 0.16 ENSMUST00000101095.2
cytidine 5'-triphosphate synthase 2
chr10_-_13324250 0.16 ENSMUST00000105543.1
phosphatase and actin regulator 2
chr1_+_17145357 0.16 ENSMUST00000026879.7
ganglioside-induced differentiation-associated-protein 1
chr1_+_179960472 0.15 ENSMUST00000097453.2
ENSMUST00000111117.1
CDC42 binding protein kinase alpha
chr5_+_145083830 0.15 ENSMUST00000031625.8
actin related protein 2/3 complex, subunit 1A
chr10_-_12964252 0.14 ENSMUST00000163425.1
ENSMUST00000042861.5
syntaxin 11
chr11_+_62551676 0.14 ENSMUST00000136938.1
ubiquitin B
chr9_+_114731177 0.14 ENSMUST00000035007.8
CKLF-like MARVEL transmembrane domain containing 6
chr10_+_79996479 0.14 ENSMUST00000132517.1
ATP-binding cassette, sub-family A (ABC1), member 7
chr10_+_123264076 0.13 ENSMUST00000050756.7
family with sequence similarity 19, member A2
chr14_+_59201418 0.13 ENSMUST00000140136.2
ENSMUST00000142326.1
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
chr4_+_134930898 0.13 ENSMUST00000030622.2
SYF2 homolog, RNA splicing factor (S. cerevisiae)
chr13_-_23762378 0.12 ENSMUST00000091701.2
histone cluster 1, H3a
chr12_+_4769375 0.12 ENSMUST00000178879.1
profilin family, member 4
chr7_+_12897800 0.12 ENSMUST00000055528.4
ENSMUST00000117189.1
ENSMUST00000120809.1
ENSMUST00000119989.1
zinc finger and SCAN domain containing 22
chr1_+_134111233 0.12 ENSMUST00000159963.1
ENSMUST00000160060.1
chitinase 1 (chitotriosidase)
chr1_-_150392719 0.11 ENSMUST00000006167.6
ENSMUST00000094477.2
ENSMUST00000097547.3
cDNA sequence BC003331
chr5_-_129708511 0.10 ENSMUST00000182386.1
septin 14
chr10_-_13324160 0.10 ENSMUST00000105545.4
phosphatase and actin regulator 2
chrX_-_75161620 0.09 ENSMUST00000165080.1
small integral membrane protein 9
chr13_-_54399246 0.09 ENSMUST00000124238.1
predicted gene 16248
chr12_-_81485073 0.08 ENSMUST00000166723.1
ENSMUST00000110340.2
ENSMUST00000168463.1
ENSMUST00000169124.1
ENSMUST00000002757.4
cytochrome c oxidase assembly protein 16
chr12_+_104101087 0.07 ENSMUST00000021495.3
serine (or cysteine) peptidase inhibitor, clade A, member 5
chr17_+_29274078 0.06 ENSMUST00000149405.2
cDNA sequence BC004004
chrX_-_147429189 0.04 ENSMUST00000033646.2
interleukin 13 receptor, alpha 2
chr7_+_126976338 0.04 ENSMUST00000032920.3
CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase)
chr13_+_59585259 0.04 ENSMUST00000168367.1
ENSMUST00000022038.7
ENSMUST00000166923.1
N(alpha)-acetyltransferase 35, NatC auxiliary subunit
chr18_-_73754457 0.03 ENSMUST00000041138.2
elaC homolog 1 (E. coli)
chr14_+_47472547 0.03 ENSMUST00000168833.1
ENSMUST00000163324.1
ENSMUST00000043112.7
F-box protein 34
chr2_-_32982007 0.02 ENSMUST00000028129.7
solute carrier family 2, (facilitated glucose transporter), member 8
chr1_-_139781236 0.02 ENSMUST00000027612.8
ENSMUST00000111989.2
ENSMUST00000111986.2
predicted gene 4788
chr12_+_69963452 0.01 ENSMUST00000110560.1
predicted gene 3086
chr4_+_102991784 0.01 ENSMUST00000140654.1
ENSMUST00000169211.1
Tctex1 domain containing 1
chr7_-_126976092 0.01 ENSMUST00000181859.1
RIKEN cDNA D830044I16 gene
chr6_+_30512283 0.01 ENSMUST00000031798.7
serine-rich single-pass membrane protein 1
chr14_+_47472628 0.01 ENSMUST00000095941.2
F-box protein 34
chr2_-_151476153 0.01 ENSMUST00000080132.2
RIKEN cDNA 4921509C19 gene
chrX_-_134111708 0.00 ENSMUST00000159259.1
ENSMUST00000113275.3
NADPH oxidase 1

Network of associatons between targets according to the STRING database.

First level regulatory network of Arid3a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0031335 regulation of sulfur amino acid metabolic process(GO:0031335)
0.2 1.2 GO:0072383 stress granule disassembly(GO:0035617) plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386) regulation of voltage-gated sodium channel activity(GO:1905150)
0.2 1.9 GO:0046449 allantoin metabolic process(GO:0000255) creatinine metabolic process(GO:0046449)
0.2 1.0 GO:0038161 prolactin signaling pathway(GO:0038161)
0.2 0.5 GO:0071332 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990) cellular response to fructose stimulus(GO:0071332)
0.2 0.7 GO:0072272 proximal/distal pattern formation involved in metanephric nephron development(GO:0072272)
0.2 0.6 GO:0061762 CAMKK-AMPK signaling cascade(GO:0061762)
0.1 0.4 GO:0010966 regulation of phosphate transport(GO:0010966)
0.1 0.4 GO:0010940 positive regulation of necrotic cell death(GO:0010940)
0.1 0.4 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.1 3.0 GO:0045838 positive regulation of membrane potential(GO:0045838)
0.1 0.4 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.0 0.1 GO:1901074 regulation of engulfment of apoptotic cell(GO:1901074)
0.0 0.2 GO:0032379 positive regulation of intracellular lipid transport(GO:0032379) positive regulation of intracellular sterol transport(GO:0032382) positive regulation of intracellular cholesterol transport(GO:0032385) lipid hydroperoxide transport(GO:1901373)
0.0 0.4 GO:0002826 negative regulation of T-helper 1 type immune response(GO:0002826)
0.0 0.3 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 0.5 GO:0034067 protein localization to Golgi apparatus(GO:0034067)
0.0 0.1 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 0.1 GO:0021888 hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888)
0.0 0.3 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.0 0.4 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.0 3.1 GO:0060349 bone morphogenesis(GO:0060349)
0.0 0.3 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.0 0.3 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.3 GO:0019236 response to pheromone(GO:0019236)
0.0 0.3 GO:0030828 positive regulation of cGMP biosynthetic process(GO:0030828)
0.0 0.3 GO:0090161 Golgi ribbon formation(GO:0090161)
0.0 0.5 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.1 GO:0043312 neutrophil degranulation(GO:0043312)
0.0 0.3 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.0 0.0 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.0 0.4 GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.0 0.2 GO:0006241 CTP biosynthetic process(GO:0006241) CTP metabolic process(GO:0046036)
0.0 0.3 GO:0040023 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.0 0.0 GO:0015755 fructose transport(GO:0015755)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:0070195 growth hormone receptor complex(GO:0070195)
0.2 3.2 GO:0043196 varicosity(GO:0043196)
0.1 0.4 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.1 1.2 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.6 GO:0020003 symbiont-containing vacuole(GO:0020003)
0.0 0.5 GO:0017119 Golgi transport complex(GO:0017119)
0.0 1.4 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.1 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 0.1 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.0 0.0 GO:0031417 NatC complex(GO:0031417)
0.0 0.2 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0 0.3 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.3 GO:0002080 acrosomal membrane(GO:0002080)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:0004903 growth hormone receptor activity(GO:0004903)
0.4 3.2 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429)
0.2 1.0 GO:0004925 prolactin receptor activity(GO:0004925)
0.2 1.2 GO:0099609 microtubule lateral binding(GO:0099609)
0.1 0.4 GO:0071568 UFM1 transferase activity(GO:0071568)
0.1 0.4 GO:0002113 interleukin-33 binding(GO:0002113)
0.1 1.4 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 0.3 GO:0008502 melatonin receptor activity(GO:0008502)
0.1 0.6 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.1 GO:0030226 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.0 0.2 GO:0050632 propanoyl-CoA C-acyltransferase activity(GO:0033814) propionyl-CoA C2-trimethyltridecanoyltransferase activity(GO:0050632) phosphatidylethanolamine transporter activity(GO:1904121)
0.0 0.2 GO:0003883 CTP synthase activity(GO:0003883)
0.0 1.9 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 3.3 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.5 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.1 GO:0004568 chitinase activity(GO:0004568)
0.0 0.3 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 0.6 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.3 GO:0016503 pheromone receptor activity(GO:0016503)
0.0 0.5 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.2 GO:0097642 calcitonin family receptor activity(GO:0097642)
0.0 0.1 GO:0032190 acrosin binding(GO:0032190)
0.0 0.3 GO:0004806 triglyceride lipase activity(GO:0004806)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 1.9 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.4 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 1.0 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 3.4 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.0 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.6 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 0.0 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 2.9 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.1 0.5 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 1.2 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 1.1 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.4 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.4 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 1.7 REACTOME REGULATION OF INSULIN SECRETION Genes involved in Regulation of Insulin Secretion