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12D miR HR13_24

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Results for Hes1

Z-value: 1.28

Motif logo

Transcription factors associated with Hes1

Gene Symbol Gene ID Gene Info
ENSMUSG00000022528.7 hes family bHLH transcription factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hes1mm10_v2_chr16_+_30065333_30065351-0.402.2e-01Click!

Activity profile of Hes1 motif

Sorted Z-values of Hes1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_17176888 2.78 ENSMUST00000170580.1
potassium voltage-gated channel, subfamily F, member 1
chr11_+_61022560 2.69 ENSMUST00000089184.4
potassium inwardly-rectifying channel, subfamily J, member 12
chr8_+_106603351 2.27 ENSMUST00000000312.5
ENSMUST00000167688.1
cadherin 1
chr2_+_157914618 2.09 ENSMUST00000109523.1
V-set and transmembrane domain containing 2-like
chr4_+_137277489 1.98 ENSMUST00000045747.4
wingless-related MMTV integration site 4
chr16_+_97356721 1.82 ENSMUST00000047275.6
beta-site APP-cleaving enzyme 2
chr5_+_141241490 1.74 ENSMUST00000085774.4
sidekick homolog 1 (chicken)
chr2_+_180725263 1.73 ENSMUST00000094218.3
solute carrier family 17, member 9
chr7_-_101864093 1.60 ENSMUST00000106981.1
folate receptor 1 (adult)
chr7_-_19796789 1.54 ENSMUST00000108449.2
ENSMUST00000043822.7
Casitas B-lineage lymphoma c
chr1_+_36511867 1.53 ENSMUST00000001166.7
ENSMUST00000097776.3
cyclin M3
chr5_-_138996087 1.42 ENSMUST00000110897.1
platelet derived growth factor, alpha
chr9_+_35211155 1.41 ENSMUST00000034541.5
signal recognition particle receptor ('docking protein')
chr16_+_30008657 1.36 ENSMUST00000181485.1
RIKEN cDNA 4632428C04 gene
chr12_-_50649190 1.33 ENSMUST00000002765.7
protein kinase D1
chr9_+_46012810 1.33 ENSMUST00000126865.1
SIK family kinase 3
chr11_-_89302545 1.29 ENSMUST00000061728.3
noggin
chr11_+_113619318 1.27 ENSMUST00000146390.2
ENSMUST00000106630.1
somatostatin receptor 2
chr5_+_104459450 1.24 ENSMUST00000086831.3
polycystic kidney disease 2
chr11_+_114765363 1.19 ENSMUST00000138804.1
ENSMUST00000084368.5
kinesin family member 19A
chr7_-_134938264 1.18 ENSMUST00000171394.1
family with sequence similarity 196, member A
chr5_-_93045022 1.17 ENSMUST00000061328.5
sosondowah ankyrin repeat domain family member B
chr2_+_155381808 1.15 ENSMUST00000043237.7
ENSMUST00000174685.1
transformation related protein 53 inducible nuclear protein 2
chr5_+_113735782 1.13 ENSMUST00000065698.5
FIC domain containing
chr9_-_75409951 1.06 ENSMUST00000049355.10
mitogen-activated protein kinase 6
chr15_+_85017138 1.04 ENSMUST00000023070.5
uroplakin 3A
chr17_-_87282793 1.03 ENSMUST00000146560.2
RIKEN cDNA 4833418N02 gene
chrX_-_106221145 1.02 ENSMUST00000113495.2
TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr18_+_65800543 0.99 ENSMUST00000025394.6
ENSMUST00000153193.1
SEC11 homolog C (S. cerevisiae)
chr10_+_26078255 0.98 ENSMUST00000041011.3
predicted gene 9767
chr1_-_84696182 0.96 ENSMUST00000049126.6
delta/notch-like EGF-related receptor
chr7_+_78913765 0.95 ENSMUST00000038142.8
interferon-stimulated protein
chr2_+_34772089 0.94 ENSMUST00000028222.6
ENSMUST00000100171.2
heat shock protein 5
chr2_+_155382186 0.92 ENSMUST00000134218.1
transformation related protein 53 inducible nuclear protein 2
chr17_-_87282771 0.92 ENSMUST00000161759.1
RIKEN cDNA 4833418N02 gene
chr17_-_26199008 0.90 ENSMUST00000142410.1
ENSMUST00000120333.1
ENSMUST00000039113.7
protein disulfide isomerase associated 2
chr11_-_12026237 0.86 ENSMUST00000150972.1
growth factor receptor bound protein 10
chr12_+_116077720 0.85 ENSMUST00000011315.3
vasoactive intestinal peptide receptor 2
chr19_-_5845471 0.83 ENSMUST00000174287.1
ENSMUST00000173672.1
nuclear paraspeckle assembly transcript 1 (non-protein coding)
chr11_+_95010277 0.83 ENSMUST00000124735.1
sterile alpha motif domain containing 14
chr2_-_172043466 0.83 ENSMUST00000087950.3
cerebellin 4 precursor protein
chrX_+_103356464 0.82 ENSMUST00000116547.2
cysteine-rich hydrophobic domain 1
chr11_+_53457184 0.82 ENSMUST00000109013.2
shroom family member 1
chr2_+_105127200 0.82 ENSMUST00000139585.1
Wilms tumor 1 homolog
chr10_+_11343387 0.80 ENSMUST00000069106.4
epilepsy, progressive myoclonic epilepsy, type 2 gene alpha
chr12_+_108792946 0.79 ENSMUST00000021692.7
YY1 transcription factor
chr14_-_29721835 0.78 ENSMUST00000022567.7
calcium channel, voltage-dependent, alpha2/delta subunit 3
chr11_-_108343917 0.78 ENSMUST00000059595.4
protein kinase C, alpha
chrX_+_20688379 0.75 ENSMUST00000033380.6
cyclin-dependent kinase 16
chr19_-_8723356 0.75 ENSMUST00000170157.1
solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2
chr8_-_107096510 0.75 ENSMUST00000068388.8
ENSMUST00000133925.1
ENSMUST00000068421.6
ENSMUST00000116425.2
telomeric repeat binding factor 2
chr11_+_100860447 0.75 ENSMUST00000107357.2
signal transducer and activator of transcription 5A
chr7_+_19083842 0.74 ENSMUST00000032568.7
ENSMUST00000122999.1
ENSMUST00000108473.3
ENSMUST00000108474.1
dystrophia myotonica-protein kinase
chr2_+_105126505 0.74 ENSMUST00000143043.1
Wilms tumor 1 homolog
chr6_-_65144908 0.74 ENSMUST00000031982.4
hematopoietic prostaglandin D synthase
chr18_-_80713062 0.73 ENSMUST00000170905.1
ENSMUST00000078049.4
nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1
chr12_+_110279228 0.72 ENSMUST00000097228.4
deiodinase, iodothyronine type III
chr2_+_69789621 0.72 ENSMUST00000151298.1
ENSMUST00000028494.2
phosphatase, orphan 2
chr2_+_69789647 0.72 ENSMUST00000112266.1
phosphatase, orphan 2
chr1_+_95313607 0.72 ENSMUST00000059975.6
family with sequence similarity 174, member A
chr10_-_24092320 0.71 ENSMUST00000092654.2
trace amine-associated receptor 8B
chr1_-_156035891 0.71 ENSMUST00000126448.1
torsin A interacting protein 1
chr3_+_144570687 0.70 ENSMUST00000106211.1
selenoprotein
chr9_-_108305941 0.70 ENSMUST00000044725.7
T cell leukemia translocation altered gene
chr15_-_78468620 0.69 ENSMUST00000017086.3
transmembrane serine protease 6
chr15_+_89322969 0.69 ENSMUST00000066991.5
adrenomedullin 2
chr4_-_58553311 0.69 ENSMUST00000107571.1
ENSMUST00000055018.4
lysophosphatidic acid receptor 1
chr7_-_99626936 0.68 ENSMUST00000178124.1
predicted gene 4980
chr5_+_107437908 0.68 ENSMUST00000094541.2
BTB (POZ) domain containing 8
chr2_-_52742169 0.67 ENSMUST00000102759.1
ENSMUST00000127316.1
signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
chr4_+_41762309 0.67 ENSMUST00000108042.2
interleukin 11 receptor, alpha chain 1
chr12_-_3357012 0.66 ENSMUST00000180719.1
predicted gene, 26520
chr13_-_48625571 0.66 ENSMUST00000035824.9
protein tyrosine phosphatase domain containing 1
chr4_-_53262547 0.66 ENSMUST00000098075.2
expressed sequence AI427809
chr7_+_28766747 0.65 ENSMUST00000170068.1
ENSMUST00000072965.4
sirtuin 2
chr7_+_78914216 0.65 ENSMUST00000120331.2
interferon-stimulated protein
chr2_-_52742142 0.65 ENSMUST00000138290.1
signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
chr4_+_65124174 0.64 ENSMUST00000084501.3
pregnancy-associated plasma protein A
chr14_-_51146757 0.64 ENSMUST00000080126.2
ribonuclease, RNase A family, 1 (pancreatic)
chr19_-_24555819 0.64 ENSMUST00000112673.2
ENSMUST00000025800.8
phosphatidylinositol-4-phosphate 5-kinase, type 1 beta
chr4_+_43562672 0.63 ENSMUST00000167751.1
ENSMUST00000132631.1
cAMP responsive element binding protein 3
chr1_-_156036473 0.63 ENSMUST00000097527.3
ENSMUST00000027738.7
torsin A interacting protein 1
chr18_+_75820174 0.62 ENSMUST00000058997.7
zinc finger and BTB domain containing 7C
chr13_+_37826904 0.61 ENSMUST00000149745.1
ras responsive element binding protein 1
chr4_-_58553553 0.60 ENSMUST00000107575.2
ENSMUST00000107574.1
ENSMUST00000147354.1
lysophosphatidic acid receptor 1
chr5_+_28071356 0.59 ENSMUST00000059155.10
insulin induced gene 1
chr4_-_58553184 0.58 ENSMUST00000145361.1
lysophosphatidic acid receptor 1
chr13_-_56296551 0.57 ENSMUST00000021970.9
chemokine (C-X-C motif) ligand 14
chr16_-_97922582 0.57 ENSMUST00000170757.1
C2 calcium-dependent domain containing 2
chr8_-_70353243 0.56 ENSMUST00000075666.6
UPF1 regulator of nonsense transcripts homolog (yeast)
chr10_+_77606571 0.56 ENSMUST00000099538.5
SMT3 suppressor of mif two 3 homolog 3 (yeast)
chr14_-_79301623 0.56 ENSMUST00000022595.7
regulator of cell cycle
chr5_+_143403819 0.54 ENSMUST00000110731.2
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
chr2_-_90580578 0.54 ENSMUST00000168621.2
protein tyrosine phosphatase, receptor type, J
chr10_-_81545175 0.53 ENSMUST00000043604.5
guanine nucleotide binding protein, alpha 11
chr8_+_83608175 0.52 ENSMUST00000005620.8
DnaJ (Hsp40) homolog, subfamily B, member 1
chr7_-_45459839 0.52 ENSMUST00000094434.4
ferritin light chain 1
chr17_+_44188564 0.52 ENSMUST00000024755.5
chloride intracellular channel 5
chr8_-_111743799 0.51 ENSMUST00000166232.2
breast cancer anti-estrogen resistance 1
chr6_+_88084473 0.51 ENSMUST00000032143.6
ribophorin I
chr2_+_28205648 0.50 ENSMUST00000102879.3
ENSMUST00000028177.4
olfactomedin 1
chr8_+_75033673 0.50 ENSMUST00000078847.5
ENSMUST00000165630.1
target of myb1 homolog (chicken)
chr9_+_46012822 0.49 ENSMUST00000120463.2
ENSMUST00000120247.1
SIK family kinase 3
chr3_+_107036156 0.49 ENSMUST00000052718.3
potassium voltage-gated channel, shaker-related subfamily, member 3
chr11_-_116086929 0.49 ENSMUST00000074628.6
ENSMUST00000106444.3
WW domain binding protein 2
chr1_+_191906743 0.48 ENSMUST00000044954.6
solute carrier family 30 (zinc transporter), member 1
chr6_-_88518760 0.48 ENSMUST00000032168.5
Sec61 alpha 1 subunit (S. cerevisiae)
chr3_+_28781305 0.47 ENSMUST00000060500.7
eukaryotic translation initiation factor 5A2
chr14_-_30626196 0.47 ENSMUST00000112210.3
ENSMUST00000112211.2
ENSMUST00000112208.1
protein kinase C, delta
chr1_-_93478785 0.47 ENSMUST00000170883.1
high density lipoprotein (HDL) binding protein
chrX_-_141725181 0.47 ENSMUST00000067841.7
insulin receptor substrate 4
chr3_-_108086590 0.46 ENSMUST00000102638.1
ENSMUST00000102637.1
adenosine monophosphate deaminase 2
chr2_-_38712195 0.46 ENSMUST00000112883.1
nuclear receptor subfamily 5, group A, member 1
chr9_+_111118070 0.45 ENSMUST00000035078.6
ENSMUST00000098340.2
leucine rich repeat (in FLII) interacting protein 2
chr17_-_26090251 0.45 ENSMUST00000040907.6
2-4-dienoyl-Coenzyme A reductase 2, peroxisomal
chr11_+_77462325 0.45 ENSMUST00000102493.1
coronin 6
chr4_+_115737738 0.45 ENSMUST00000106525.2
EF-hand calcium binding domain 14
chr18_-_15403680 0.44 ENSMUST00000079081.6
aquaporin 4
chr1_+_93754899 0.44 ENSMUST00000027502.9
autophagy related 4B, cysteine peptidase
chr15_+_79028212 0.44 ENSMUST00000180086.1
H1 histone family, member 0
chr2_-_168741752 0.44 ENSMUST00000029060.4
ATPase, class II, type 9A
chr5_-_36695969 0.44 ENSMUST00000031091.9
ENSMUST00000140063.1
DNA segment, Chr 5, ERATO Doi 579, expressed
chr10_+_79854658 0.43 ENSMUST00000171599.1
ENSMUST00000095457.4
polypyrimidine tract binding protein 1
chr17_+_28232723 0.43 ENSMUST00000002320.8
peroxisome proliferator activator receptor delta
chr6_+_86526271 0.43 ENSMUST00000180896.1
RIKEN cDNA 1600020E01 gene
chr4_+_126753770 0.43 ENSMUST00000102607.3
ENSMUST00000047431.4
ENSMUST00000132660.1
expressed sequence AU040320
chr15_-_39112642 0.42 ENSMUST00000022908.8
solute carrier family 25, member 32
chr10_+_79854618 0.42 ENSMUST00000165704.1
polypyrimidine tract binding protein 1
chr1_+_120340569 0.42 ENSMUST00000037286.8
complement component 1, q subcomponent-like 2
chr9_+_118040509 0.41 ENSMUST00000133580.1
5-azacytidine induced gene 2
chr11_+_98348404 0.41 ENSMUST00000078694.6
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr7_-_29906087 0.41 ENSMUST00000053521.8
zinc finger protein 27
chr19_+_3851972 0.41 ENSMUST00000025760.6
choline kinase alpha
chr11_+_53457209 0.41 ENSMUST00000018531.5
shroom family member 1
chr15_-_95528228 0.41 ENSMUST00000075275.2
NEL-like 2
chr1_-_175692624 0.41 ENSMUST00000027809.7
opsin 3
chr7_+_99535652 0.40 ENSMUST00000032995.8
ENSMUST00000162404.1
arrestin, beta 1
chr11_+_121434913 0.40 ENSMUST00000026175.2
ENSMUST00000092302.4
ENSMUST00000103014.3
fructosamine 3 kinase
chr4_-_145246855 0.40 ENSMUST00000030336.4
tumor necrosis factor receptor superfamily, member 1b
chr11_-_100527862 0.40 ENSMUST00000107385.1
ATP citrate lyase
chr5_-_108629712 0.39 ENSMUST00000046603.8
cyclin G associated kinase
chr4_+_116877376 0.39 ENSMUST00000044823.3
zinc finger SWIM-type containing 5
chr7_+_80343091 0.39 ENSMUST00000032747.5
HD domain containing 3
chr5_+_110176640 0.39 ENSMUST00000112512.1
golgi autoantigen, golgin subfamily a, 3
chr11_-_116828000 0.39 ENSMUST00000047715.5
ENSMUST00000021170.2
matrix-remodelling associated 7
chr9_+_75410145 0.38 ENSMUST00000180533.1
ENSMUST00000180574.1
RIKEN cDNA 4933433G15 gene
chrX_+_42067876 0.38 ENSMUST00000126375.1
X-linked inhibitor of apoptosis
chr11_+_69095217 0.38 ENSMUST00000101004.2
period circadian clock 1
chr6_-_70792155 0.38 ENSMUST00000066134.5
ribose 5-phosphate isomerase A
chr11_-_66525964 0.37 ENSMUST00000066679.6
shisa homolog 6 (Xenopus laevis)
chr9_-_87255536 0.37 ENSMUST00000093802.4
RIKEN cDNA 4922501C03 gene
chr11_-_106788845 0.37 ENSMUST00000123339.1
DEAD (Asp-Glu-Ala-Asp) box polypeptide 5
chr7_+_99535439 0.37 ENSMUST00000098266.2
ENSMUST00000179755.1
arrestin, beta 1
chr14_-_70443442 0.36 ENSMUST00000000793.5
polymerase (RNA) III (DNA directed) polypeptide D
chr2_+_23069057 0.36 ENSMUST00000114526.1
ENSMUST00000114529.2
acyl-Coenzyme A binding domain containing 5
chr5_-_31220491 0.36 ENSMUST00000031032.7
protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform
chr3_+_127633134 0.36 ENSMUST00000029587.7
neurogenin 2
chr4_+_115737754 0.36 ENSMUST00000106522.2
EF-hand calcium binding domain 14
chr11_-_21371143 0.35 ENSMUST00000060895.5
UDP-glucose pyrophosphorylase 2
chr7_+_19004047 0.35 ENSMUST00000053713.3
interferon regulatory factor 2 binding protein 1
chr4_-_129696817 0.35 ENSMUST00000102588.3
transmembrane protein 39b
chrX_-_155338460 0.35 ENSMUST00000026328.4
peroxiredoxin 4
chr14_-_70443219 0.35 ENSMUST00000180358.1
polymerase (RNA) III (DNA directed) polypeptide D
chr8_-_105938384 0.34 ENSMUST00000034369.8
proteasome (prosome, macropain) subunit, beta type 10
chr15_+_76331288 0.34 ENSMUST00000172281.1
GPI anchor attachment protein 1
chr6_+_17636983 0.33 ENSMUST00000015877.7
capping protein (actin filament) muscle Z-line, alpha 2
chr1_+_88095054 0.33 ENSMUST00000150634.1
ENSMUST00000058237.7
UDP glucuronosyltransferase 1 family, polypeptide A7C
chrX_-_49886401 0.33 ENSMUST00000070304.2
olfactory receptor 1322
chr11_+_120673018 0.33 ENSMUST00000106158.2
ENSMUST00000103016.1
ENSMUST00000168714.1
alveolar soft part sarcoma chromosome region, candidate 1 (human)
chr1_+_33908172 0.33 ENSMUST00000182513.1
ENSMUST00000183034.1
dystonin
chr10_-_53750880 0.33 ENSMUST00000020003.7
family with sequence similarity 184, member A
chr7_-_35585577 0.32 ENSMUST00000069912.4
regulator of G-protein signalling 9 binding protein
chr4_-_45012287 0.32 ENSMUST00000055028.8
ENSMUST00000180217.1
ENSMUST00000107817.2
zinc finger and BTB domain containing 5
chr2_+_153345809 0.32 ENSMUST00000109790.1
additional sex combs like 1
chr7_+_25897620 0.32 ENSMUST00000072438.6
ENSMUST00000005477.5
cytochrome P450, family 2, subfamily b, polypeptide 10
chr3_-_146685592 0.32 ENSMUST00000125965.1
sterile alpha motif domain containing 13
chr2_+_162931520 0.32 ENSMUST00000130411.1
serine/arginine-rich splicing factor 6
chr15_+_66577536 0.32 ENSMUST00000048188.8
PHD finger protein 20-like 1
chr10_-_78487842 0.31 ENSMUST00000069431.4
predicted gene 9978
chr3_+_90254163 0.31 ENSMUST00000029545.8
CREB regulated transcription coactivator 2
chr2_+_156840966 0.31 ENSMUST00000109564.1
TGFB-induced factor homeobox 2
chr12_-_87200200 0.31 ENSMUST00000037418.5
transmembrane emp24 domain containing 8
chr2_+_158028687 0.30 ENSMUST00000109518.1
ENSMUST00000029180.7
regulation of nuclear pre-mRNA domain containing 1B
chr7_-_34655500 0.30 ENSMUST00000032709.1
potassium channel tetramerisation domain containing 15
chr18_+_70568189 0.30 ENSMUST00000074058.4
ENSMUST00000114946.3
methyl-CpG binding domain protein 2
chr5_+_34369909 0.30 ENSMUST00000180376.1
family with sequence similarity 193, member A
chr3_-_116712198 0.30 ENSMUST00000120120.1
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member 3
chr14_+_34673888 0.30 ENSMUST00000048263.7
wings apart-like homolog (Drosophila)
chr5_+_93093428 0.29 ENSMUST00000074733.7
septin 11
chr2_+_158028481 0.29 ENSMUST00000103123.3
regulation of nuclear pre-mRNA domain containing 1B
chr11_-_100759942 0.29 ENSMUST00000107363.2
potassium voltage-gated channel, subfamily H (eag-related), member 4
chr5_+_135149657 0.29 ENSMUST00000153183.1
transducin (beta)-like 2
chr6_-_149101674 0.29 ENSMUST00000111557.1
DENN/MADD domain containing 5B
chr2_+_144368961 0.29 ENSMUST00000028911.8
ENSMUST00000147747.1
ENSMUST00000183618.1
cysteine and glycine-rich protein 2 binding protein
PET117 homolog (S. cerevisiae)
chr11_+_51763682 0.28 ENSMUST00000020653.5
SAR1 gene homolog B (S. cerevisiae)
chr11_+_11685909 0.28 ENSMUST00000065433.5
IKAROS family zinc finger 1
chr8_-_124949165 0.28 ENSMUST00000034469.5
EGL nine homolog 1 (C. elegans)
chr17_+_28769307 0.28 ENSMUST00000004986.6
mitogen-activated protein kinase 13
chr4_+_32983008 0.28 ENSMUST00000098190.3
ENSMUST00000029946.7
Ras-related GTP binding D
chr11_-_106789157 0.28 ENSMUST00000129585.1
DEAD (Asp-Glu-Ala-Asp) box polypeptide 5

Network of associatons between targets according to the STRING database.

First level regulatory network of Hes1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0061054 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748) dermatome development(GO:0061054) regulation of dermatome development(GO:0061183) renal vesicle induction(GO:0072034) metanephric mesenchymal cell differentiation(GO:0072162)
0.5 1.6 GO:0072302 posterior mesonephric tubule development(GO:0072166) negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302) regulation of metanephric ureteric bud development(GO:2001074) positive regulation of metanephric ureteric bud development(GO:2001076)
0.5 1.4 GO:0010512 negative regulation of phosphatidylinositol biosynthetic process(GO:0010512)
0.5 1.9 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.5 2.3 GO:0060066 oviduct development(GO:0060066)
0.4 1.3 GO:0060300 regulation of cytokine activity(GO:0060300)
0.4 1.2 GO:0009726 detection of nodal flow(GO:0003127) detection of endogenous stimulus(GO:0009726)
0.3 1.6 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.3 0.9 GO:0021577 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)
0.3 0.8 GO:1902530 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
0.3 0.8 GO:0071707 immunoglobulin heavy chain V-D-J recombination(GO:0071707)
0.3 1.8 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.2 0.7 GO:0072695 negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695)
0.2 0.7 GO:0060854 patterning of lymph vessels(GO:0060854)
0.2 0.4 GO:0070295 renal water absorption(GO:0070295)
0.2 1.1 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.2 0.6 GO:0019046 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990) establishment of viral latency(GO:0019043) release from viral latency(GO:0019046)
0.2 0.4 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.2 0.8 GO:2000705 negative regulation of anion channel activity(GO:0010360) regulation of dense core granule biogenesis(GO:2000705)
0.2 1.3 GO:0089700 protein kinase D signaling(GO:0089700)
0.2 0.7 GO:0060376 positive regulation of mast cell differentiation(GO:0060376)
0.2 0.7 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.2 0.6 GO:0003331 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.2 1.6 GO:0003147 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713) cellular response to folic acid(GO:0071231)
0.2 0.5 GO:1990859 cellular response to endothelin(GO:1990859)
0.2 0.7 GO:0061428 positive regulation of oocyte development(GO:0060282) negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428) negative regulation of defense response to bacterium(GO:1900425)
0.2 0.5 GO:0071579 regulation of zinc ion transport(GO:0071579)
0.2 0.8 GO:0015820 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.1 1.0 GO:0015840 urea transport(GO:0015840)
0.1 0.6 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.1 0.6 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.1 0.6 GO:0044565 dendritic cell proliferation(GO:0044565)
0.1 1.9 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.1 1.3 GO:0071763 nuclear membrane organization(GO:0071763)
0.1 0.3 GO:0060423 foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492)
0.1 0.4 GO:0006011 UDP-glucose metabolic process(GO:0006011) glucose 1-phosphate metabolic process(GO:0019255)
0.1 0.7 GO:0072675 osteoclast fusion(GO:0072675)
0.1 0.5 GO:2000195 negative regulation of female gonad development(GO:2000195)
0.1 0.6 GO:0032201 telomere maintenance via semi-conservative replication(GO:0032201)
0.1 0.3 GO:0009804 coumarin metabolic process(GO:0009804) phenylpropanoid catabolic process(GO:0046271)
0.1 0.4 GO:0051697 protein delipidation(GO:0051697)
0.1 1.3 GO:0030432 peristalsis(GO:0030432)
0.1 0.5 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.1 0.4 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.1 0.3 GO:0045660 positive regulation of neutrophil differentiation(GO:0045660)
0.1 0.3 GO:0033122 negative regulation of purine nucleotide catabolic process(GO:0033122)
0.1 0.5 GO:0060697 glucosylceramide catabolic process(GO:0006680) positive regulation of phospholipid catabolic process(GO:0060697)
0.1 0.4 GO:0006014 D-ribose metabolic process(GO:0006014)
0.1 0.7 GO:0019336 phenol-containing compound catabolic process(GO:0019336)
0.1 0.3 GO:1903722 regulation of centriole elongation(GO:1903722)
0.1 1.0 GO:0007220 Notch receptor processing(GO:0007220)
0.1 0.6 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.1 0.4 GO:0030423 targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.1 0.4 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.1 0.9 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719)
0.1 0.5 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.1 1.5 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.1 1.8 GO:0048148 behavioral response to cocaine(GO:0048148)
0.1 0.3 GO:0035522 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.1 0.8 GO:0046959 habituation(GO:0046959)
0.1 0.3 GO:0042738 exogenous drug catabolic process(GO:0042738)
0.1 0.8 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.1 0.5 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.1 0.2 GO:0090265 immune complex clearance by monocytes and macrophages(GO:0002436) astrocyte chemotaxis(GO:0035700) regulation of immune complex clearance by monocytes and macrophages(GO:0090264) positive regulation of immune complex clearance by monocytes and macrophages(GO:0090265) negative regulation of eosinophil activation(GO:1902567) positive regulation of CD8-positive, alpha-beta T cell extravasation(GO:2000451) regulation of astrocyte chemotaxis(GO:2000458)
0.1 0.5 GO:0035437 protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.1 2.7 GO:0010107 potassium ion import(GO:0010107)
0.1 0.2 GO:0006222 UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.1 0.4 GO:0097167 circadian regulation of translation(GO:0097167)
0.1 0.2 GO:0015680 intracellular copper ion transport(GO:0015680)
0.1 0.8 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.1 0.7 GO:0097264 self proteolysis(GO:0097264)
0.1 0.3 GO:0015788 UDP-N-acetylglucosamine transport(GO:0015788)
0.1 0.6 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.1 0.4 GO:0060468 prevention of polyspermy(GO:0060468)
0.1 0.4 GO:0019695 choline metabolic process(GO:0019695)
0.1 0.2 GO:2000611 basement membrane disassembly(GO:0034769) positive regulation of thyroid hormone generation(GO:2000611)
0.1 1.0 GO:0006465 signal peptide processing(GO:0006465)
0.1 0.5 GO:0032264 IMP salvage(GO:0032264)
0.1 0.2 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
0.1 0.2 GO:0043686 co-translational protein modification(GO:0043686)
0.1 0.5 GO:0031547 brain-derived neurotrophic factor receptor signaling pathway(GO:0031547)
0.1 0.2 GO:0021506 anterior neuropore closure(GO:0021506) neuropore closure(GO:0021995)
0.1 0.2 GO:1900738 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.1 0.4 GO:0043415 vitamin A metabolic process(GO:0006776) positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.1 0.4 GO:0030242 pexophagy(GO:0030242)
0.1 0.2 GO:1904798 regulation of core promoter binding(GO:1904796) positive regulation of core promoter binding(GO:1904798)
0.1 0.5 GO:0002756 MyD88-independent toll-like receptor signaling pathway(GO:0002756)
0.0 0.1 GO:0007308 oocyte construction(GO:0007308) oocyte axis specification(GO:0007309) oocyte anterior/posterior axis specification(GO:0007314) pole plasm assembly(GO:0007315) maternal determination of anterior/posterior axis, embryo(GO:0008358) P granule organization(GO:0030719)
0.0 0.5 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.0 0.1 GO:0032241 positive regulation of nucleobase-containing compound transport(GO:0032241)
0.0 0.3 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.0 0.5 GO:0023041 neuronal signal transduction(GO:0023041)
0.0 0.3 GO:0045583 regulation of cytotoxic T cell differentiation(GO:0045583) positive regulation of cytotoxic T cell differentiation(GO:0045585)
0.0 0.6 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.0 0.5 GO:0090084 chaperone cofactor-dependent protein refolding(GO:0070389) negative regulation of inclusion body assembly(GO:0090084)
0.0 0.3 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.0 1.8 GO:0060351 cartilage development involved in endochondral bone morphogenesis(GO:0060351)
0.0 0.4 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.0 0.3 GO:0043201 response to leucine(GO:0043201) cellular response to leucine(GO:0071233)
0.0 0.2 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.7 GO:0046697 decidualization(GO:0046697)
0.0 0.8 GO:0030575 nuclear body organization(GO:0030575)
0.0 0.1 GO:0060168 positive regulation of adenosine receptor signaling pathway(GO:0060168) regulation of G-protein coupled receptor internalization(GO:1904020)
0.0 0.8 GO:0030252 growth hormone secretion(GO:0030252)
0.0 0.5 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.0 0.4 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.1 GO:0035905 ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910)
0.0 0.6 GO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060)
0.0 0.2 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.0 0.5 GO:0002024 diet induced thermogenesis(GO:0002024)
0.0 0.3 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 0.3 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.0 0.2 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.9 GO:1902175 regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902175)
0.0 2.1 GO:1903008 organelle disassembly(GO:1903008)
0.0 0.2 GO:1901750 cysteine biosynthetic process(GO:0019344) leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.0 0.3 GO:0043970 histone H3-K9 acetylation(GO:0043970)
0.0 0.3 GO:0042711 maternal behavior(GO:0042711)
0.0 2.2 GO:0000045 autophagosome assembly(GO:0000045)
0.0 0.2 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0 0.4 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.4 GO:0006085 acetyl-CoA biosynthetic process(GO:0006085)
0.0 0.3 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.1 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0 0.1 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.0 0.1 GO:0003416 endochondral bone growth(GO:0003416)
0.0 0.2 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0 0.4 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.1 GO:0043519 myosin II filament organization(GO:0031038) regulation of myosin II filament organization(GO:0043519)
0.0 0.4 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.3 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.2 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.2 GO:0032836 glomerular basement membrane development(GO:0032836)
0.0 0.1 GO:0032227 negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.0 0.1 GO:0050915 sensory perception of sour taste(GO:0050915)
0.0 0.2 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.2 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.0 0.0 GO:0060466 activation of meiosis involved in egg activation(GO:0060466)
0.0 0.3 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.7 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.1 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.0 0.3 GO:0038092 nodal signaling pathway(GO:0038092)
0.0 0.2 GO:0036010 protein localization to endosome(GO:0036010)
0.0 0.1 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.1 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0 0.8 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.0 0.0 GO:0090649 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.0 0.4 GO:0070498 interleukin-1-mediated signaling pathway(GO:0070498)
0.0 0.0 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.0 0.7 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.3 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.1 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.0 0.4 GO:0006636 unsaturated fatty acid biosynthetic process(GO:0006636)
0.0 0.1 GO:0043981 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 0.0 GO:0006499 N-terminal protein myristoylation(GO:0006499) N-terminal peptidyl-glycine N-myristoylation(GO:0018008)
0.0 0.6 GO:0006661 phosphatidylinositol biosynthetic process(GO:0006661)
0.0 0.4 GO:0006040 amino sugar metabolic process(GO:0006040)
0.0 2.1 GO:0043524 negative regulation of neuron apoptotic process(GO:0043524)
0.0 0.4 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.5 GO:0018196 peptidyl-asparagine modification(GO:0018196) protein N-linked glycosylation via asparagine(GO:0018279)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.0 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.2 2.9 GO:0043219 lateral loop(GO:0043219)
0.2 1.4 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.1 0.5 GO:0099522 region of cytosol(GO:0099522) postsynaptic cytosol(GO:0099524)
0.1 0.7 GO:0030870 Mre11 complex(GO:0030870)
0.1 1.0 GO:0005787 signal peptidase complex(GO:0005787)
0.1 0.8 GO:0042382 paraspeckles(GO:0042382)
0.1 0.6 GO:0044530 supraspliceosomal complex(GO:0044530)
0.1 0.5 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.1 0.4 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.1 0.6 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 0.4 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.1 0.4 GO:0044308 axonal spine(GO:0044308)
0.1 0.3 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 0.9 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 0.3 GO:0031673 H zone(GO:0031673)
0.1 0.6 GO:0071141 SMAD protein complex(GO:0071141)
0.1 1.3 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.1 1.1 GO:0032156 septin cytoskeleton(GO:0032156)
0.1 1.3 GO:0000421 autophagosome membrane(GO:0000421)
0.1 0.3 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 0.8 GO:0031011 Ino80 complex(GO:0031011)
0.1 0.7 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.6 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.8 GO:0031143 pseudopodium(GO:0031143)
0.0 0.5 GO:0044754 autolysosome(GO:0044754)
0.0 0.7 GO:0000124 SAGA complex(GO:0000124)
0.0 2.1 GO:0005776 autophagosome(GO:0005776)
0.0 3.6 GO:0030315 T-tubule(GO:0030315)
0.0 0.5 GO:0090543 Flemming body(GO:0090543)
0.0 0.7 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 1.2 GO:0016460 myosin II complex(GO:0016460)
0.0 0.3 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 1.6 GO:0015030 Cajal body(GO:0015030)
0.0 0.1 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.3 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.2 GO:0098642 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.0 0.1 GO:0035061 interchromatin granule(GO:0035061)
0.0 0.2 GO:0045098 type III intermediate filament(GO:0045098)
0.0 0.2 GO:1903439 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.0 0.7 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.1 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.0 2.4 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.1 GO:0044194 cytolytic granule(GO:0044194)
0.0 0.5 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.4 GO:0043196 varicosity(GO:0043196)
0.0 0.6 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.3 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 1.4 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.2 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.2 GO:0036038 MKS complex(GO:0036038)
0.0 0.6 GO:0032420 stereocilium(GO:0032420)
0.0 0.3 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.5 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.5 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 1.0 GO:0005902 microvillus(GO:0005902)
0.0 0.5 GO:0001772 immunological synapse(GO:0001772)
0.0 0.9 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.1 GO:0000782 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.6 GO:0008859 exoribonuclease II activity(GO:0008859)
0.4 1.4 GO:0033883 pyridoxal phosphatase activity(GO:0033883)
0.3 1.2 GO:0048763 calcium-induced calcium release activity(GO:0048763)
0.3 1.9 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.3 0.8 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
0.3 0.8 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.3 1.3 GO:0004994 somatostatin receptor activity(GO:0004994)
0.2 0.7 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.2 0.7 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.2 1.6 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.2 0.6 GO:0035500 MH2 domain binding(GO:0035500)
0.2 0.8 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.2 0.6 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.2 1.4 GO:0005047 signal recognition particle binding(GO:0005047)
0.2 0.7 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.2 0.7 GO:0004921 interleukin-11 receptor activity(GO:0004921) interleukin-11 binding(GO:0019970)
0.2 0.7 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.2 0.8 GO:2001070 starch binding(GO:2001070)
0.1 0.4 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.1 1.6 GO:0051870 methotrexate binding(GO:0051870)
0.1 0.4 GO:0016501 prostacyclin receptor activity(GO:0016501)
0.1 2.3 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 0.8 GO:0001069 regulatory region RNA binding(GO:0001069)
0.1 0.4 GO:0031750 D3 dopamine receptor binding(GO:0031750) D5 dopamine receptor binding(GO:0031752)
0.1 0.5 GO:0046923 ER retention sequence binding(GO:0046923)
0.1 1.0 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.1 1.2 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.1 0.5 GO:0070976 TIR domain binding(GO:0070976)
0.1 0.4 GO:0004104 cholinesterase activity(GO:0004104)
0.1 1.4 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 2.7 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.1 0.6 GO:0016892 endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.1 0.6 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.1 0.5 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.1 0.7 GO:0001594 trace-amine receptor activity(GO:0001594)
0.1 0.2 GO:0035717 chemokine (C-C motif) ligand 7 binding(GO:0035717)
0.1 0.7 GO:0003720 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.1 1.8 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.1 0.4 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.1 0.4 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.1 0.4 GO:0015288 porin activity(GO:0015288)
0.1 1.3 GO:0004697 protein kinase C activity(GO:0004697)
0.1 0.5 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 0.2 GO:0043682 copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682)
0.1 0.5 GO:0070097 delta-catenin binding(GO:0070097)
0.1 0.2 GO:0004948 calcitonin receptor activity(GO:0004948)
0.1 0.7 GO:0004579 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 2.0 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.9 GO:0051787 misfolded protein binding(GO:0051787)
0.0 2.2 GO:0005109 frizzled binding(GO:0005109)
0.0 0.4 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.3 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0 0.9 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.2 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.0 0.5 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.0 3.4 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 0.6 GO:0031386 protein tag(GO:0031386)
0.0 0.0 GO:0098847 sequence-specific single stranded DNA binding(GO:0098847)
0.0 1.8 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.4 GO:0008517 folic acid transporter activity(GO:0008517)
0.0 0.5 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.3 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.4 GO:0032557 pyrimidine ribonucleotide binding(GO:0032557)
0.0 1.2 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.7 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.8 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 0.7 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.4 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 1.1 GO:0070566 adenylyltransferase activity(GO:0070566)
0.0 0.2 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.0 0.2 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.4 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.2 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.0 0.5 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.4 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.2 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.1 GO:0031687 A2A adenosine receptor binding(GO:0031687)
0.0 0.9 GO:0005112 Notch binding(GO:0005112)
0.0 1.4 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.1 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 0.3 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.1 GO:0035939 microsatellite binding(GO:0035939)
0.0 0.1 GO:0016401 palmitoyl-CoA oxidase activity(GO:0016401)
0.0 0.2 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 0.1 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.0 0.1 GO:0070012 oligopeptidase activity(GO:0070012)
0.0 2.1 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.3 GO:0070330 aromatase activity(GO:0070330)
0.0 2.0 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.3 GO:0051920 peroxiredoxin activity(GO:0051920)
0.0 0.6 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.6 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.3 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.3 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.6 GO:0008009 chemokine activity(GO:0008009)
0.0 0.1 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.8 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.4 GO:0030332 cyclin binding(GO:0030332)
0.0 0.3 GO:0005549 odorant binding(GO:0005549)
0.0 0.2 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.2 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.7 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.2 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.1 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.4 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.6 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 0.0 GO:0019107 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107)
0.0 0.3 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.3 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.8 GO:0097110 scaffold protein binding(GO:0097110)
0.0 0.4 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 1.0 GO:0019955 cytokine binding(GO:0019955)
0.0 0.3 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.1 GO:0043995 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.3 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.1 3.2 PID IGF1 PATHWAY IGF1 pathway
0.0 0.8 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.7 PID IL5 PATHWAY IL5-mediated signaling events
0.0 2.1 PID BMP PATHWAY BMP receptor signaling
0.0 0.6 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.6 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 1.4 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.8 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 2.1 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.4 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 1.6 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 2.0 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 1.8 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 2.0 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.8 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.2 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.4 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.7 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.4 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 2.1 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.5 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.2 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 0.1 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.6 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 0.2 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.8 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.3 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.4 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.1 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.8 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.3 PID RHODOPSIN PATHWAY Visual signal transduction: Rods

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.3 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 1.3 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 0.9 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 1.0 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.1 3.6 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 1.1 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 0.8 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.1 0.7 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.1 2.6 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 3.7 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.4 REACTOME OPSINS Genes involved in Opsins
0.0 0.9 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.7 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 1.3 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.7 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.4 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.2 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 1.8 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.5 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 0.4 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.7 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.3 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.3 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 1.6 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.4 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 0.4 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.5 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.4 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.3 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.4 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.5 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 1.6 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.0 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.3 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.3 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.3 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.5 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.6 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.5 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.6 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.5 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.1 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.6 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.3 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.9 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.2 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.0 0.4 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.4 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 1.6 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events