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12D miR HR13_24

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Results for Gli1

Z-value: 0.45

Motif logo

Transcription factors associated with Gli1

Gene Symbol Gene ID Gene Info
ENSMUSG00000025407.6 GLI-Kruppel family member GLI1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Gli1mm10_v2_chr10_-_127341583_127341614-0.412.1e-01Click!

Activity profile of Gli1 motif

Sorted Z-values of Gli1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_107529717 0.94 ENSMUST00000049285.8
leucine rich repeat protein 1, neuronal
chr2_+_70562007 0.80 ENSMUST00000094934.4
glutamate decarboxylase 1
chr8_+_76902277 0.77 ENSMUST00000109912.1
ENSMUST00000128862.1
ENSMUST00000109911.1
nuclear receptor subfamily 3, group C, member 2
chr8_-_72212837 0.76 ENSMUST00000098630.3
calcium and integrin binding family member 3
chr7_-_100656953 0.76 ENSMUST00000107046.1
ENSMUST00000107045.1
ENSMUST00000139708.1
pleckstrin homology domain containing, family B (evectins) member 1
chrX_+_103321398 0.60 ENSMUST00000033689.2
caudal type homeobox 4
chr8_+_54954728 0.57 ENSMUST00000033915.7
glycoprotein m6a
chr2_+_119351222 0.54 ENSMUST00000028780.3
ChaC, cation transport regulator 1
chr2_-_152830615 0.49 ENSMUST00000146380.1
ENSMUST00000134902.1
ENSMUST00000134357.1
ENSMUST00000109820.3
BCL2-like 1
chr14_+_55560480 0.47 ENSMUST00000121622.1
ENSMUST00000143431.1
ENSMUST00000150481.1
DDB1 and CUL4 associated factor 11
chr7_-_118443549 0.47 ENSMUST00000081574.4
synaptotagmin XVII
chr2_-_152831112 0.45 ENSMUST00000128172.1
BCL2-like 1
chr1_+_195017399 0.44 ENSMUST00000181273.1
RIKEN cDNA A330023F24 gene
chr14_+_55560904 0.42 ENSMUST00000072530.4
ENSMUST00000128490.1
DDB1 and CUL4 associated factor 11
chr14_+_55561060 0.41 ENSMUST00000117701.1
DDB1 and CUL4 associated factor 11
chr14_-_55560340 0.40 ENSMUST00000066106.3
RIKEN cDNA A730061H03 gene
chrX_-_7574120 0.35 ENSMUST00000045924.7
ENSMUST00000115742.2
ENSMUST00000150787.1
protein phosphatase 1, regulatory (inhibitor) subunit 3F
chr2_+_105127200 0.35 ENSMUST00000139585.1
Wilms tumor 1 homolog
chr9_-_108305941 0.35 ENSMUST00000044725.7
T cell leukemia translocation altered gene
chr6_-_52012476 0.33 ENSMUST00000078214.5
src family associated phosphoprotein 2
chr4_+_62480025 0.33 ENSMUST00000030088.5
ENSMUST00000107449.3
B-box and SPRY domain containing
chr11_-_58733223 0.32 ENSMUST00000075607.2
olfactory receptor 317
chr3_-_92485886 0.32 ENSMUST00000054599.7
small proline-rich protein 1A
chr12_+_44328882 0.32 ENSMUST00000020939.8
ENSMUST00000110748.2
neuron-glia-CAM-related cell adhesion molecule
chr4_-_58553311 0.31 ENSMUST00000107571.1
ENSMUST00000055018.4
lysophosphatidic acid receptor 1
chr11_-_96824008 0.29 ENSMUST00000142065.1
ENSMUST00000167110.1
ENSMUST00000169828.1
ENSMUST00000126949.1
nuclear factor, erythroid derived 2,-like 1
chr17_+_37045980 0.28 ENSMUST00000174456.1
gamma-aminobutyric acid (GABA) B receptor, 1
chr6_+_125349699 0.26 ENSMUST00000032491.8
tumor necrosis factor receptor superfamily, member 1a
chr5_+_30588078 0.26 ENSMUST00000066295.2
potassium channel, subfamily K, member 3
chr8_-_64733534 0.26 ENSMUST00000141021.1
sterol-C4-methyl oxidase-like
chr10_-_64090265 0.25 ENSMUST00000105439.1
leucine rich repeat transmembrane neuronal 3
chr3_+_90603767 0.25 ENSMUST00000001046.5
ENSMUST00000107330.1
S100 calcium binding protein A4
chr11_+_93098404 0.24 ENSMUST00000107859.1
ENSMUST00000042943.6
ENSMUST00000107861.1
ENSMUST00000107858.2
carbonic anhydrase 10
chr4_-_58553553 0.24 ENSMUST00000107575.2
ENSMUST00000107574.1
ENSMUST00000147354.1
lysophosphatidic acid receptor 1
chr11_-_94704499 0.23 ENSMUST00000069852.1
predicted gene 11541
chr9_+_118506226 0.22 ENSMUST00000084820.4
golgi autoantigen, golgin subfamily a, 4
chr2_+_106693185 0.22 ENSMUST00000111063.1
metallophosphoesterase domain containing 2
chr15_+_99392882 0.21 ENSMUST00000023749.8
transmembrane BAX inhibitor motif containing 6
chr6_+_30738044 0.21 ENSMUST00000128398.1
ENSMUST00000163949.2
ENSMUST00000124665.1
mesoderm specific transcript
chr1_+_191906743 0.20 ENSMUST00000044954.6
solute carrier family 30 (zinc transporter), member 1
chr4_-_58553184 0.20 ENSMUST00000145361.1
lysophosphatidic acid receptor 1
chr15_+_99392948 0.20 ENSMUST00000161250.1
ENSMUST00000160635.1
ENSMUST00000161778.1
transmembrane BAX inhibitor motif containing 6
chr5_-_134456227 0.20 ENSMUST00000111244.1
general transcription factor II I repeat domain-containing 1
chr3_+_92288566 0.20 ENSMUST00000090872.4
small proline-rich protein 2A3
chr9_+_108306205 0.19 ENSMUST00000007959.8
ras homolog gene family, member A
chr4_+_117096049 0.19 ENSMUST00000030443.5
patched homolog 2
chr13_-_53377355 0.19 ENSMUST00000021920.6
serine palmitoyltransferase, long chain base subunit 1
chr4_+_114821722 0.19 ENSMUST00000137570.1
predicted gene 12830
chr11_+_62847111 0.19 ENSMUST00000150989.1
ENSMUST00000176577.1
F-box and WD-40 domain protein 10
chr11_-_42182163 0.19 ENSMUST00000153147.1
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1
chr4_-_43454600 0.19 ENSMUST00000098105.3
ENSMUST00000098104.3
ENSMUST00000030179.4
CD72 antigen
chr18_-_70141568 0.18 ENSMUST00000121693.1
RAB27b, member RAS oncogene family
chr18_-_35662180 0.18 ENSMUST00000025209.4
ENSMUST00000096573.2
spermatogenesis associated 24
chr2_-_151973840 0.18 ENSMUST00000109865.1
ENSMUST00000109864.1
family with sequence similarity 110, member A
chr4_+_12140263 0.16 ENSMUST00000050069.2
ENSMUST00000069128.7
RNA binding motif protein 12 B1
chr4_+_12089373 0.16 ENSMUST00000095143.2
ENSMUST00000063839.5
RNA binding motif protein 12 B2
chr18_+_37477768 0.16 ENSMUST00000051442.5
protocadherin beta 16
chr7_-_24760311 0.16 ENSMUST00000063956.5
CD177 antigen
chr17_+_34187545 0.16 ENSMUST00000170086.1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr7_-_139978709 0.16 ENSMUST00000121412.1
RIKEN cDNA 6430531B16 gene
chr2_-_29253001 0.15 ENSMUST00000071201.4
netrin G2
chr1_-_75232093 0.15 ENSMUST00000180101.1
RIKEN cDNA A630095N17 gene
chr9_-_50752348 0.15 ENSMUST00000042790.3
heat shock protein 2
chr19_+_11404735 0.15 ENSMUST00000153546.1
membrane-spanning 4-domains, subfamily A, member 4C
chr5_-_122900267 0.15 ENSMUST00000031435.7
lysine (K)-specific demethylase 2B
chr16_+_64851991 0.15 ENSMUST00000067744.7
CGG triplet repeat binding protein 1
chrX_-_59568068 0.15 ENSMUST00000119833.1
ENSMUST00000131319.1
fibroblast growth factor 13
chr2_+_164879358 0.15 ENSMUST00000041643.3
PDX1 C-terminal inhibiting factor 1
chr3_-_116007399 0.15 ENSMUST00000067485.3
solute carrier family 30 (zinc transporter), member 7
chr3_-_89402650 0.14 ENSMUST00000168325.1
ENSMUST00000057431.5
lens epithelial protein
chr5_-_122989260 0.14 ENSMUST00000118027.1
lysine (K)-specific demethylase 2B
chr17_+_86963279 0.14 ENSMUST00000139344.1
ras homolog gene family, member Q
chr11_+_62847062 0.14 ENSMUST00000036085.4
F-box and WD-40 domain protein 10
chr13_-_58385190 0.14 ENSMUST00000022032.5
RIKEN cDNA 2210016F16 gene
chr11_+_115420059 0.14 ENSMUST00000103035.3
potassium channel tetramerisation domain containing 2
chr19_-_6084679 0.13 ENSMUST00000161548.1
zinc finger like protein 1
chr10_+_93488766 0.13 ENSMUST00000129421.1
histidine ammonia lyase
chr17_-_24209377 0.13 ENSMUST00000024931.4
netrin 3
chr4_+_40948401 0.13 ENSMUST00000030128.5
charged multivesicular body protein 5
chr6_+_17463749 0.13 ENSMUST00000115443.1
met proto-oncogene
chr2_+_23069210 0.13 ENSMUST00000155602.1
acyl-Coenzyme A binding domain containing 5
chr11_+_80300866 0.13 ENSMUST00000017836.7
rhomboid, veinlet-like 3 (Drosophila)
chr7_-_19770509 0.13 ENSMUST00000003061.7
basal cell adhesion molecule
chr6_+_67115671 0.13 ENSMUST00000181304.1
RIKEN cDNA A430010J10 gene
chrX_+_119927196 0.13 ENSMUST00000040961.2
ENSMUST00000113366.1
poly(A) binding protein, cytoplasmic 5
chr8_+_45658731 0.12 ENSMUST00000143820.1
ENSMUST00000132139.1
sorbin and SH3 domain containing 2
chr17_+_34187789 0.12 ENSMUST00000041633.8
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr5_-_122989086 0.12 ENSMUST00000046073.9
lysine (K)-specific demethylase 2B
chr14_+_25607797 0.12 ENSMUST00000160229.1
zinc finger, MIZ-type containing 1
chr7_+_24370255 0.12 ENSMUST00000171904.1
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr9_+_50752758 0.12 ENSMUST00000034562.7
crystallin, alpha B
chr15_-_95528228 0.12 ENSMUST00000075275.2
NEL-like 2
chr2_-_36104060 0.12 ENSMUST00000112961.3
ENSMUST00000112966.3
LIM homeobox protein 6
chr2_+_181520485 0.12 ENSMUST00000072334.5
DnaJ (Hsp40) homolog, subfamily C, member 5
chr4_-_43454563 0.12 ENSMUST00000107926.1
CD72 antigen
chr2_-_104493690 0.11 ENSMUST00000111124.1
homeodomain interacting protein kinase 3
chr6_-_52246214 0.11 ENSMUST00000048026.8
homeobox A11
chr6_+_95117740 0.11 ENSMUST00000032107.7
ENSMUST00000119582.1
kelch repeat and BTB (POZ) domain containing 8
chr9_+_104063678 0.11 ENSMUST00000047799.5
acyl-Coenzyme A dehydrogenase family, member 11
chr18_-_10610124 0.11 ENSMUST00000097670.3
establishment of cohesion 1 homolog 1 (S. cerevisiae)
chr2_+_32535315 0.11 ENSMUST00000133512.1
ENSMUST00000048375.5
family with sequence similarity 102, member A
chr7_-_6331235 0.11 ENSMUST00000127658.1
ENSMUST00000062765.7
zinc finger protein 583
chr15_-_100584075 0.11 ENSMUST00000184908.1
POU domain, class 6, transcription factor 1 (Pou6f1), mRNA
chrX_+_155262443 0.11 ENSMUST00000026324.9
acyl-CoA thioesterase 9
chr11_+_73240310 0.11 ENSMUST00000138853.1
transient receptor potential cation channel, subfamily V, member 1
chr6_-_122609964 0.11 ENSMUST00000032211.4
growth differentiation factor 3
chr6_-_113531575 0.11 ENSMUST00000032425.5
ER membrane protein complex subunit 3
chr2_+_23069057 0.11 ENSMUST00000114526.1
ENSMUST00000114529.2
acyl-Coenzyme A binding domain containing 5
chr4_-_43454582 0.11 ENSMUST00000107925.1
CD72 antigen
chr11_+_115420138 0.11 ENSMUST00000106533.1
ENSMUST00000123345.1
potassium channel tetramerisation domain containing 2
chr1_-_153900198 0.11 ENSMUST00000123490.1
RIKEN cDNA 5830403L16 gene
chr11_+_60479915 0.10 ENSMUST00000126522.1
myosin XV
chr3_+_116007457 0.10 ENSMUST00000029575.5
ENSMUST00000106501.1
exostoses (multiple)-like 2
chr17_+_37045963 0.10 ENSMUST00000025338.9
gamma-aminobutyric acid (GABA) B receptor, 1
chr14_+_60378242 0.10 ENSMUST00000022561.6
APC membrane recruitment 2
chr2_-_104494400 0.10 ENSMUST00000028600.7
homeodomain interacting protein kinase 3
chr5_+_5573952 0.10 ENSMUST00000101627.2
predicted gene 8773
chr8_+_45658666 0.10 ENSMUST00000134675.1
ENSMUST00000139869.1
ENSMUST00000126067.1
sorbin and SH3 domain containing 2
chr18_-_10610048 0.10 ENSMUST00000115864.1
establishment of cohesion 1 homolog 1 (S. cerevisiae)
chr11_+_96282648 0.10 ENSMUST00000168043.1
homeobox B8
chr11_+_100415722 0.09 ENSMUST00000107400.2
FK506 binding protein 10
chr1_-_125912160 0.09 ENSMUST00000159417.1
Ly6/Plaur domain containing 1
chr2_-_92434027 0.09 ENSMUST00000111278.1
ENSMUST00000090559.5
cryptochrome 2 (photolyase-like)
chr6_+_37870786 0.09 ENSMUST00000120428.1
ENSMUST00000031859.7
tripartite motif-containing 24
chr11_+_4135167 0.09 ENSMUST00000003677.4
ENSMUST00000145705.1
ring finger protein 215
chr6_+_17463826 0.09 ENSMUST00000140070.1
met proto-oncogene
chr6_-_3763618 0.09 ENSMUST00000171613.1
calcitonin receptor
chr5_+_91074611 0.09 ENSMUST00000031324.4
epiregulin
chr19_-_3575708 0.09 ENSMUST00000113997.2
ENSMUST00000025846.8
ENSMUST00000172362.1
protein phosphatase 6, regulatory subunit 3
chr17_+_34238914 0.09 ENSMUST00000167280.1
histocompatibility 2, O region beta locus
chr16_-_91011093 0.09 ENSMUST00000170853.1
ENSMUST00000118390.2
synaptojanin 1
chr7_+_141216626 0.09 ENSMUST00000141804.1
ENSMUST00000148975.1
Ras association (RalGDS/AF-6) domain family (N-terminal) member 7
chr1_+_133350510 0.09 ENSMUST00000094556.2
renin 1 structural
chr11_+_78245743 0.09 ENSMUST00000002133.8
stromal cell derived factor 2
chr2_+_181520533 0.09 ENSMUST00000108797.1
DnaJ (Hsp40) homolog, subfamily C, member 5
chr11_-_99422252 0.08 ENSMUST00000017741.3
keratin 12
chr6_+_17463927 0.08 ENSMUST00000115442.1
met proto-oncogene
chr10_-_64090241 0.08 ENSMUST00000133588.1
leucine rich repeat transmembrane neuronal 3
chr7_-_142372342 0.08 ENSMUST00000059223.8
interferon induced transmembrane protein 10
chr19_-_5085483 0.08 ENSMUST00000140389.1
ENSMUST00000151413.1
ENSMUST00000077066.7
transmembrane protein 151A
chr8_-_25038875 0.08 ENSMUST00000084031.4
HtrA serine peptidase 4
chr4_+_133011506 0.08 ENSMUST00000105915.1
ENSMUST00000105916.1
AT hook, DNA binding motif, containing 1
chr5_-_115436508 0.08 ENSMUST00000078701.3
RIKEN cDNA 4930430O22 gene
chr1_+_152954966 0.08 ENSMUST00000043313.8
nicotinamide nucleotide adenylyltransferase 2
chr15_-_85581809 0.08 ENSMUST00000023015.7
wingless-related MMTV integration site 7B
chr7_-_142372210 0.08 ENSMUST00000084412.5
interferon induced transmembrane protein 10
chr13_-_9764943 0.07 ENSMUST00000110634.1
zinc finger, MYND domain containing 11
chr19_+_55316313 0.07 ENSMUST00000095950.2
vesicle transport through interaction with t-SNAREs 1A
chr7_+_135268579 0.07 ENSMUST00000097983.3
neuropeptide S
chr4_-_83021102 0.07 ENSMUST00000071708.5
Fras1 related extracellular matrix protein 1
chr5_-_123721007 0.07 ENSMUST00000031376.7
zinc finger, CCHC domain containing 8
chr8_-_105966038 0.07 ENSMUST00000116429.2
ENSMUST00000034370.9
solute carrier family 12, member 4
chr11_-_42000532 0.07 ENSMUST00000070735.3
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2
chr17_+_56326045 0.06 ENSMUST00000139679.1
ENSMUST00000025036.4
ENSMUST00000086835.5
lysine (K)-specific demethylase 4B
chr7_+_5020561 0.06 ENSMUST00000085427.3
zinc finger protein 865
chr18_-_10610346 0.06 ENSMUST00000025142.5
establishment of cohesion 1 homolog 1 (S. cerevisiae)
chr17_+_34238896 0.06 ENSMUST00000095342.3
histocompatibility 2, O region beta locus
chr17_-_57031468 0.06 ENSMUST00000007814.8
KH-type splicing regulatory protein
chr3_-_45378206 0.06 ENSMUST00000181047.1
RIKEN cDNA 2610316D01 gene
chr11_+_97840780 0.05 ENSMUST00000054783.4
RIKEN cDNA B230217C12 gene
chr18_+_37355271 0.05 ENSMUST00000051163.1
protocadherin beta 8
chr7_+_80186835 0.05 ENSMUST00000107383.1
ENSMUST00000032754.7
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
chr2_+_129800451 0.05 ENSMUST00000165413.2
ENSMUST00000166282.2
serine/threonine kinase 35
chr11_+_35769462 0.05 ENSMUST00000018990.7
pantothenate kinase 3
chr9_+_55149364 0.05 ENSMUST00000121677.1
ubiquitin-conjugating enzyme E2Q (putative) 2
chr4_-_155863362 0.05 ENSMUST00000030949.3
taste receptor, type 1, member 3
chr4_+_144892813 0.05 ENSMUST00000105744.1
ENSMUST00000171001.1
dehydrogenase/reductase (SDR family) member 3
chr8_+_45658273 0.04 ENSMUST00000153798.1
sorbin and SH3 domain containing 2
chr11_+_85311232 0.04 ENSMUST00000020835.9
protein phosphatase 1D magnesium-dependent, delta isoform
chr6_-_41636389 0.04 ENSMUST00000031902.5
transient receptor potential cation channel, subfamily V, member 6
chr2_+_76369967 0.04 ENSMUST00000046389.4
RNA binding motif protein 45
chr11_-_61494173 0.04 ENSMUST00000101085.2
ENSMUST00000079080.6
ENSMUST00000108714.1
mitogen-activated protein kinase 7
chr4_+_118428078 0.04 ENSMUST00000006557.6
ENSMUST00000167636.1
ENSMUST00000102673.4
elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1
chr17_+_86963077 0.04 ENSMUST00000024956.8
ras homolog gene family, member Q
chr15_-_78544345 0.04 ENSMUST00000053239.2
somatostatin receptor 3
chr16_-_90284412 0.04 ENSMUST00000039280.7
SR-related CTD-associated factor 4
chr15_+_34082664 0.04 ENSMUST00000022865.9
metadherin
chr7_-_140950236 0.04 ENSMUST00000026562.4
interferon induced transmembrane protein 5
chr7_-_138397704 0.03 ENSMUST00000160436.1
transcription elongation regulator 1-like
chr16_-_56024628 0.03 ENSMUST00000119981.1
ENSMUST00000096021.3
PEST proteolytic signal containing nuclear protein
chr1_-_192834719 0.03 ENSMUST00000057543.2
RIKEN cDNA A730013G03 gene
chr16_-_91011029 0.03 ENSMUST00000130813.1
synaptojanin 1
chr1_-_56972437 0.03 ENSMUST00000042857.7
special AT-rich sequence binding protein 2
chr8_+_121127827 0.02 ENSMUST00000181609.1
forkhead box L1
chrX_+_94234594 0.02 ENSMUST00000153900.1
kelch-like 15
chr2_-_121456693 0.02 ENSMUST00000110613.2
ENSMUST00000056312.3
serine incorporator 4
chr4_+_144893077 0.02 ENSMUST00000154208.1
dehydrogenase/reductase (SDR family) member 3
chr11_+_63061599 0.02 ENSMUST00000035732.4
tektin 3
chr3_+_45378396 0.02 ENSMUST00000166126.1
ENSMUST00000170695.1
ENSMUST00000171554.1
protocadherin 10
chr11_+_77009265 0.02 ENSMUST00000129572.2
solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
chr9_-_82975475 0.02 ENSMUST00000034787.5
pleckstrin homology domain interacting protein
chr7_+_73391160 0.02 ENSMUST00000128471.1
RGM domain family, member A
chr11_+_115462464 0.02 ENSMUST00000106532.3
ENSMUST00000092445.5
ENSMUST00000153466.1
solute carrier family 16 (monocarboxylic acid transporters), member 5
chr13_-_117025505 0.01 ENSMUST00000022239.6
poly (ADP-ribose) polymerase family, member 8
chr17_+_25727726 0.01 ENSMUST00000047273.1
RNA pseudouridylate synthase domain containing 1
chr14_+_19751257 0.01 ENSMUST00000022340.3
nidogen 2
chr2_+_120629113 0.01 ENSMUST00000150912.1
ENSMUST00000180041.1
START domain containing 9
chrX_+_101299207 0.01 ENSMUST00000065858.2
neuroligin 3
chr11_+_9191934 0.01 ENSMUST00000042740.6
ATP-binding cassette, sub-family A (ABC1), member 13
chr16_+_92498122 0.01 ENSMUST00000023670.3
chloride intracellular channel 6

Network of associatons between targets according to the STRING database.

First level regulatory network of Gli1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0031959 mineralocorticoid receptor signaling pathway(GO:0031959)
0.2 0.9 GO:0046898 response to cycloheximide(GO:0046898)
0.2 0.7 GO:1904566 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.1 0.3 GO:2001074 negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302) regulation of metanephric ureteric bud development(GO:2001074) positive regulation of metanephric ureteric bud development(GO:2001076)
0.1 0.8 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.1 0.4 GO:0031437 regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.1 0.4 GO:0021993 initiation of neural tube closure(GO:0021993)
0.1 0.2 GO:0071579 regulation of zinc ion transport(GO:0071579)
0.1 0.2 GO:1990868 response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869)
0.1 0.2 GO:0006667 sphinganine metabolic process(GO:0006667)
0.1 0.4 GO:0014053 negative regulation of gamma-aminobutyric acid secretion(GO:0014053)
0.1 0.3 GO:0072675 osteoclast fusion(GO:0072675)
0.1 0.3 GO:0046967 cytosol to ER transport(GO:0046967)
0.1 0.3 GO:0034421 post-translational protein acetylation(GO:0034421)
0.1 0.3 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.0 0.2 GO:0009957 epidermal cell fate specification(GO:0009957)
0.0 0.5 GO:0006751 glutathione catabolic process(GO:0006751)
0.0 0.3 GO:0070495 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.0 0.2 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.0 0.3 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.2 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.1 GO:1904980 regulation of endosome organization(GO:1904978) positive regulation of endosome organization(GO:1904980)
0.0 0.1 GO:0002587 negative regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002587)
0.0 0.2 GO:0030242 pexophagy(GO:0030242)
0.0 0.1 GO:0006548 histidine catabolic process(GO:0006548)
0.0 0.1 GO:2000847 negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850)
0.0 0.1 GO:0002018 renin-angiotensin regulation of aldosterone production(GO:0002018)
0.0 0.1 GO:1901594 detection of temperature stimulus involved in thermoception(GO:0050960) response to capsazepine(GO:1901594)
0.0 0.4 GO:2000465 regulation of glycogen (starch) synthase activity(GO:2000465)
0.0 0.4 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.1 GO:0045196 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.0 0.1 GO:0010841 positive regulation of circadian sleep/wake cycle, wakefulness(GO:0010841)
0.0 0.3 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.0 0.1 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 0.1 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0 0.1 GO:0016332 establishment or maintenance of polarity of embryonic epithelium(GO:0016332) renal outer medulla development(GO:0072054) inner medullary collecting duct development(GO:0072061) metanephric loop of Henle development(GO:0072236)
0.0 0.1 GO:0048165 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.0 0.3 GO:1903140 regulation of endothelial cell development(GO:1901550) regulation of establishment of endothelial barrier(GO:1903140)
0.0 0.5 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.0 0.1 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.1 GO:0061303 cornea development in camera-type eye(GO:0061303)
0.0 0.1 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.1 GO:0061088 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.0 0.1 GO:0034628 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.0 0.7 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.0 0.2 GO:0071420 cellular response to histamine(GO:0071420)
0.0 0.3 GO:0031424 keratinization(GO:0031424)
0.0 0.1 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.0 GO:0070375 ERK5 cascade(GO:0070375)
0.0 0.1 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0 0.2 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.1 GO:0048859 formation of anatomical boundary(GO:0048859)
0.0 0.1 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
0.0 0.1 GO:0014029 neural crest formation(GO:0014029)
0.0 0.1 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0 0.6 GO:0009948 anterior/posterior axis specification(GO:0009948)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 0.4 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.0 0.2 GO:0035339 SPOTS complex(GO:0035339)
0.0 0.2 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 0.2 GO:0032585 multivesicular body membrane(GO:0032585)
0.0 0.3 GO:0042825 TAP complex(GO:0042825)
0.0 0.5 GO:0001533 cornified envelope(GO:0001533)
0.0 1.3 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.8 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.1 GO:1903440 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.0 0.1 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.1 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.2 GO:1902711 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 0.1 GO:0097512 cardiac myofibril(GO:0097512)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0017082 mineralocorticoid receptor activity(GO:0017082)
0.1 0.8 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.1 0.5 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.1 0.7 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.1 0.3 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 0.9 GO:0051434 BH3 domain binding(GO:0051434)
0.1 0.4 GO:2001069 glycogen binding(GO:2001069)
0.1 0.3 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.1 0.3 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.1 0.4 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.1 0.2 GO:0008158 smoothened binding(GO:0005119) hedgehog receptor activity(GO:0008158)
0.1 0.4 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.1 0.3 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433) tapasin binding(GO:0046980)
0.0 0.3 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.0 0.2 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.3 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.1 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.0 0.3 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 0.1 GO:0001888 glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0001888)
0.0 0.2 GO:1904315 GABA-gated chloride ion channel activity(GO:0022851) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.2 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.1 GO:0004948 calcitonin receptor activity(GO:0004948)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.5 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.1 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.0 0.1 GO:0016841 ammonia-lyase activity(GO:0016841)
0.0 0.1 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.0 0.2 GO:0051022 Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0 0.1 GO:1902379 chemoattractant activity involved in axon guidance(GO:1902379)
0.0 0.1 GO:0097603 temperature-gated ion channel activity(GO:0097603)
0.0 0.3 GO:0022841 potassium ion leak channel activity(GO:0022841) S100 protein binding(GO:0044548)
0.0 0.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.1 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0 0.1 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.2 GO:0005522 profilin binding(GO:0005522)
0.0 0.1 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.2 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.2 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.0 0.1 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.3 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.2 PID S1P S1P4 PATHWAY S1P4 pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 1.0 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.4 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.3 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.9 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 0.3 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.3 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.3 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.3 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.2 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation